29th week of 2014 patent applcation highlights part 40 |
Patent application number | Title | Published |
20140200091 | METHODS, APPARATUS, AND SYSTEMS TO CUSTOM FIT GOLF CLUBS - Embodiments of methods, apparatus, and systems to custom fit golf clubs are generally described herein. Other embodiments may be described and claimed. | 2014-07-17 |
20140200092 | METHOD AND APPARATUS FOR DETERMINING A RELATIVE ORIENTATION OF POINTS ON A RIGID BODY - An inertial measurement unit is affixed to a rigid body. The inertial measurement includes a gyroscope that measures a first angular velocity and an angular acceleration; a first accelerometer that measures a first acceleration; a communications unit that receives a measurement signal, the measurement signal including a second acceleration transmitted from a second accelerometer, the second accelerometer being affixed to the rigid body; and a controller that calculates a relative orientation of the inertial measurement unit and the second accelerometer, and a distance separating the inertial measurement unit and the second accelerometer. | 2014-07-17 |
20140200093 | APPARATUS FOR PROVIDING MOTION SENSORS ON A GOLF CLUB - A fixed clamping member has a first interior surface and is constructed of a first material. A sensor unit formed on an exterior surface of the fixed clamping member detects a motion of the motion analysis device. A pivoting clamping member secured to a first end of the fixed clamping member has a second interior surface that opposes the first interior surface when the pivoting clamping member is in a secured position. A gripping element constructed of a second material different than the first material is formed over the first interior surface and the second interior surface. A tightening member having a threaded portion is secured to a second end of the fixed clamping member. A knob has a threaded interior portion with a diameter corresponding to the cylindrical threaded portion. An opening on the pivoting clamping member has a shape and a size corresponding to the tightening member. | 2014-07-17 |
20140200094 | DEVICE AND METHOD FOR RECONSTRUCTING AND ANALYZING MOTION OF A RIGID BODY - An information processing apparatus includes circuitry configured to acquire information corresponding to a reference orientation that indicates a spatial position of a sensor unit attached to a golf club. The reference orientation is determined based on a vector projecting in a normal direction from a planar surface of the golf club. The circuitry acquires a measurement signal generated by the sensor unit in response to a movement of the golf club, the measurement signal including measurements of one or more of an angular acceleration, a linear acceleration, and an angular velocity. The circuitry generates data corresponding to a motion path of the golf club based on the measurement signal and the reference orientation. The circuitry controls an interface to output the generated data corresponding to the motion path. | 2014-07-17 |
20140200095 | GOLF PUTTER - Disclosed is a golf putter which includes a putter head which includes a toe and a heel and is formed with a putting line groove on an upper surface of a plane portion; and a support which connects the putter head and a shaft and is formed with an upper horizontal line parallel with the putting line groove. | 2014-07-17 |
20140200096 | Transition Pilot - A protruding device is used to encumber a user's ability to maneuver his/her hips beyond its position while executing/simulating a golf swing. The protruding device comprises a telescopic beam, having a ball affixed to one end and a pointed, coaxial, coned tip affixed to the other. Additionally, options exist for attachment to a weighted base, specifically designed for indoor application or operability on non-penetrable surfaces. | 2014-07-17 |
20140200097 | Golf putter grip - A golf putter grip comprises a main tubular body having a non-circular cross-section being symmetrical and remaining similar throughout its axial length, and a flat front area also along and throughout its axial length. The non-circular cross-section and the flat front area respectively have a width dimension sufficient to have two hands cupped together at the same height and two thumbs placed side by side on the flat front area to hold the putter grip comfortably with minimal wrist breaking-down. The main tubular body has flat-topped arch cross-section and is reversely tapered, and its reverse taper is sufficient in certain degrees to accommodate different finger lengths of two hands for reducing the gripping pressure, so as to make the gripping comfortable. | 2014-07-17 |
20140200098 | GOLF BALL WITH SOFT FEEL - A golf ball comprising:
| 2014-07-17 |
20140200099 | Multi-Arm Dimple and Dimple Patterns Including Same - A golf hall dimple having a plurality of arms wherein each arm includes a leading edge, a trailing edge, side walls, and a sloped floor. The dimples of the invention may be included in a dimple pattern that may also include other types of dimples. | 2014-07-17 |
20140200100 | GOLF BALL - In a golf ball having a core and a cover of at least one layer, an outermost layer of the cover is formed to a specific thickness using a resin composition containing a light-harvesting fluorescent dye and a light-reflecting pigment. The golf ball is elegant and highly stylish, and moreover has an excellent visibility. | 2014-07-17 |
20140200101 | BASEBALL HITTING AID - A baseball hitting aid is a device that includes a base plate and a rear pole that can be moved progressively forward to aid a batter in learning to shorten his swing and become a better hitter. The device can include a tee portion for practice or it can be used when the ball is pitched to the batter. | 2014-07-17 |
20140200102 | Adjustable Basketball Training Apparatus - An adjustable basketball training apparatus comprising an upper portion having a horizontal obstruction supported by one or more support members and a lower portion movably attached to said support members such that the height of the horizontal obstruction may be adjusted to force a player to release a basketball with a desirable trajectory toward the intended target, such as a basket or another player, and methods for use thereof. The training apparatus is adjustable and may include vertical obstructions extending from the horizontal obstruction, attachments that simulate all or part of a defender, means for distracting a player, and a ball storage rack. | 2014-07-17 |
20140200103 | BASKETBALL ELECTRONICS SUPPORT - A game ball supports electronics. In one implementation, the electronics sense motion of the game ball and are encapsulated by potting compound which forms an encapsulating body sized and shaped to fit within a cavity of the game ball. In one implementation, a game ball comprises an inflatable body which supports the electronics, wherein an electrical conductive line is electrically connected to electronics extends along a surface of the inflatable body at least 60 degrees about the inflatable body. | 2014-07-17 |
20140200104 | CHAIN TENSIONER - To provide a chain tensioner that has a simple structure, is universally usable, is capable of supplying sufficient and necessary oil when restarted after a long time after the stop of oil supply, enables reduction in entire length and size, and enables easy production and reduction in production cost. An urging unit | 2014-07-17 |
20140200105 | SAFETY APPARATUS FOR USE WITH A SHEAVE - A safety apparatus safety apparatus for use with a sheave has a first plate suitable for placement over one side of the sheave, a second plate suitable for placement on an opposite side of the sheave, and a carriage positioned at a periphery of the first and second plates. The carriage extends across a gap between the plates. The carriage is movable along the peripheries of the first and second plates. The carnage includes a lust carriage and a second carriage which are independently movable with respect to each other. The carriage includes a first body, a second body, and a discoidal member pivotally mounted to the first and second bodies. The discoidal member has a hole suitable for allowing the cable of the sheave to pass freely therethrough. | 2014-07-17 |
20140200106 | INVERTED TOOTH CHAIN AND SPROCKET DRIVE SYSTEM WITH REDUCED MESHING IMPACT - An inverted tooth chain and sprocket drive system in which the initial contact distance IC | 2014-07-17 |
20140200107 | V-BELT FOR TRANSMITTING HIGH LOAD - On each block side face of the blocks of a V-belt for transmitting high load, a ratio of a dimension extending in a belt thickness direction from a buried cord center line of a corresponding tension band to an upper end of an upper pulley-contact face to a dimension extending in the belt thickness direction from the buried cord center line to a lower end of the upper pulley-contact face is larger than or equal to 4.0, and a dimension extending in the belt thickness direction from the buried cord center line to a middle of the upper pulley-contact face is smaller than or equal to 2.3 mm. | 2014-07-17 |
20140200108 | CVT BELT - A vulcanized rubber CVT belt in the form of an endless V-belt having a belt body with angled sides, a tensile cord layer of helically spiraled tensile cord embedded in the belt body, an overcord rubber layer, and an undercord rubber layer, wherein the tensile cord is a twisted, single-tow bundle of continuous-filament, carbon fiber impregnated with an adhesive treatment and/or overcoated with adhesive compatible with the rubber of the tensile cord layer. The tow may be 18K. The carbon fiber may have a filament diameter of from about 6.0 to about 6.4-micron, a tensile modulus of from about 200 to about 300 GPa, an elongation at break of from about 1.9% to about 2.3%. | 2014-07-17 |
20140200109 | Planetary Gear Pump - A planetary gear pump comprising a central gear and a plurality of planet pairs provides a space efficient transducer between hydraulic and mechanical energy. When it is configured as a pump, a high flow rate is provided. When it is configured as an actuator, a high torque is provided. A dual-stage configuration may be used as a low speed high torque actuator with high energy efficiency, high pitch velocity, and low slippage. | 2014-07-17 |
20140200110 | CONTINUOUSLY VARIABLE TRANSMISSION - A continuously variable transmission includes each planetary ball sandwiched between first and second rotation members on a shaft and a sun roller; a first carrier configured to be rotatable relatively with the shaft as a center and formed with a first guide portion that guides one projection of each support shaft of each planetary ball in a radial direction; a second carrier formed with a second guide portion that guides the other projection of each support shaft in the radial direction; and an iris plate configured to include a throttle portion that holds one projection of the support shaft at an intersection point with the first guide portion formed when seen in an axis line direction, the intersection point being moved in the radial direction with the rotation. | 2014-07-17 |
20140200111 | HYBRID VEHICLE CONTROL APPARATUS - A hybrid vehicle control apparatus ( | 2014-07-17 |
20140200112 | CONTROL APPARATUS FOR VEHICLE - Disclosed is a control apparatus for a vehicle including: a belt continuously variable transmission capable of continuously changing a gear ratio; and a forward/reverse switching mechanism capable of controlling a state of power transmission between an engine and the belt continuously variable transmission. The control apparatus is configured to, at re-acceleration following deceleration, perform an input clutch slip control to place a forward clutch of the forward/reverse switching mechanism in a slipping engagement position and thus increase an engine revolution speed. | 2014-07-17 |
20140200113 | COASTING DOWNSHIFT CONTROL DEVICE FOR AUTOMATIC TRANSMISSION - Under a specified condition where a torque converter is kept in a lockup state to prolong the fuel-cutoff time, because of vehicle coasting with an accelerator opening APO=0, a downshift command is generated and then an automatic transmission causes a reengagement downshift by a drop in a release-side clutch hydraulic pressure Poff and a rise in an engagement-side clutch hydraulic pressure Pon. During the reengagement downshift, the engagement-side clutch hydraulic pressure Pon is reduced from a high lockup-ON hydraulic pressure to a low lockup-OFF hydraulic pressure after the time when the lockup is predicted to be released, thus preventing a torque drawing-in tendency of transmission output torque, which may occur at the time of the beginning of the inertia phase, from increasing, and also reducing in the width of a subsequent change in vehicle deceleration G, and consequently enhancing the shift quality. | 2014-07-17 |
20140200114 | Method Of Calibration Of A Park Brake Of A Continuously Variable Transmission - A method of calibrating a hydraulically operated park brake of a continuously variable transmission of a vehicle. With the vehicle moving at a set, slow speed within a specified range, and the park brake off, a search technique is used, wherein the brake hydraulic pressure is reduced by application of a control signal of a selected test value to apply the brake. When the selected test value is reached, it is held constant, and a condition in a HSU of the transmission is monitored for a change indicative of engagement of the park brake. This will expectedly be in the form of a pressure change and more particularly an increase indicating initial contact between the plates of the brake, and if the HSU change is not detected, the step will time out and another control signal value will be tested. | 2014-07-17 |
20140200115 | WRIST TRAINING BALL AND INFORMATION DISPLAY AND DETECTING MODULE THEREOF - A wrist training ball includes a housing, a rotating body rotatably disposed in the housing, a magnetic component and an information display and detecting module. The magnetic component, disposed at the rotating body, spins with the rotating body. The information display and detecting module, disposed at the housing, includes a sensing unit, a rectifying unit, a signal transforming unit and a processing unit. The sensing unit generates an induced current when the rotating body is spun. The rectifying unit, electrically connected to the sensing unit, rectifies the induced current into an operating power. The signal transforming unit, electrically connected to the sensing unit, transforms the induced current into a motion datum. The processing unit, electrically connected to the rectifying unit and the signal transforming unit, receives the operating power for operation and processes the motion datum to determine a relative motion relationship between the rotating body and the housing. | 2014-07-17 |
20140200116 | Real Time Feedback Swim Training System and Method Based on Instantaneous Speed - A swim training system and method includes a signal delivery sub-system configured to deliver signals to the swimmer and a machine vision sub-system with a detector and a target marker to be worn by a swimmer. The detector is configured to detect the target marker. A controller is configured to operably control the machine vision sub-system. A data processing sub-system is configured to process data collected by the machine vision sub-system and to generate signals for the signal delivery system. During a swim training session, the detector tracks a location of the target marker and transmits speed data to the data processing sub-system. The data processing sub-system processes the speed data and generates signals that are transmitted to the swimmer via the signal delivery sub-system in real time during the swim session. The signals are representative of a real time speed characteristic of the swimmer. | 2014-07-17 |
20140200117 | Moveable Bar Catch with Support - A gym system is described. The gym system includes multiple vertical support members, each support member comprising a set of locking receptacles, and a moveable bar catch having a tubular body adapted to slide along at least one vertical support member, and a pivoting locking feature comprising a protuberance adapted to engage a particular locking receptacle from among the set of locking receptacles. A bar catch including a tubular body adapted to be able to be positioned along a support member of a weightlifting support apparatus is also described. The bar catch includes a solid hook adapted to support a weightlifting bar and to pivot at one end, allowing the solid hook to be placed in a moveable first position and a locked second position, a safety support adapted to provide support to the solid hook and the weightlifting bar, and a handle coupled to the tubular body. | 2014-07-17 |
20140200118 | WEIGHTED BODY SUIT - A weighted body suit for exercise purposes comprising: a pair of sleeves; a pair of pants legs; a zipper; ankle level weight attachments; pants leg weight attachments; a detachable waist weight; and a chest and shoulder weight harness. The waist weight may include a belt connector to enable attachment and de-attachment of the waist weight around the waist area of the weighted body suit. The chest and shoulder harness may alo include a connector to enable attachment and de-attachment of the chest and shoulder harness around the chest and shoulder area of the weighted body suit. Each weight attachment weighs in a range of about 5 pounds to about 10 pounds. | 2014-07-17 |
20140200119 | BARBELL ASSEMBLY HAVING IMPACT ABSORBING WEIGHTS AND SWIVEL END - A barbell assembly includes a bar and a weight subassembly adjacent each end of the bar. Each weight subassembly includes a wheel with a predetermined pattern of through holes and an inflatable component around the periphery of the wheel. A hub defines a flange having a plurality of through holes corresponding to the through holes on the wheel for securing the wheel to the hub with fasteners. The hub is secured to the bar with fasteners, or the flange is secured to the bar by welding or with fasteners. An outer end of the bar is provided with a U-shaped swivel having a hook that rotates freely relative to the outer end and the grip portion of the bar. The barbell assembly may be utilized to perform weight training exercises without causing damage to an exercise surface, and may be locked to an immovable fixture using a tether and a lock. | 2014-07-17 |
20140200120 | MODULAR RESISTANCE FORCE SYSTEM - A modular resistance force system includes an axle configured to be rotatable around a rotational axis and one or more resistance mechanisms. Each of the one or more resistance mechanisms includes a resistance element disposed about a portion of the axle, a resistance element housing configured to house the resistance element and a resistance substance disposed between the resistance element and the resistance element housing. Either the resistance element or the resistance element housing is selectively engaged to rotate with the axle. A resistance between the resistance element and the resistance substance causes a force to be applied to the axle when the resistance element and the resistance element housing move relative to each other. | 2014-07-17 |
20140200121 | DETACHABLE COMPONENT MUSCLE TONING GARMENT - Disclosed is a muscle toning garment with detachable, interchangeable resistance elements. The garment provides resistance training throughout an angular range of motion. The garment may be low profile, and worn by a wearer as a primary garment or beneath conventional clothing. Toning may thereby be accomplished throughout the wearer's normal daily activities, without the need for access to conventional exercise equipment. Alternatively, the device may be worn as a supplemental training tool during conventional training techniques. | 2014-07-17 |
20140200122 | Mobile Training Device - The present invention relates to a mobile training device having bi-directional, variable resistive forces for training a baseball swing and other sports involving weight transfer and hip rotation. | 2014-07-17 |
20140200123 | EXERCISE APPARATUS INCLUDING A DIP BAR - An exercise apparatus that includes a plurality of dip bars arranged in a non-parallel orientation and supported on an elongated self-supporting stand, which is supported on a base. The self-supporting stand may include a plurality of elongated supports that are spaced from one another. The support and the dip bars may be arranged along first and second parallel planes that extend away from the self-supporting stand in the same direction. | 2014-07-17 |
20140200124 | Physical Therapy Device and Methods for Use Thereof - The present application relates to a physical therapy device to strengthen and prevent atrophy in muscles for use while seated in a chair or a wheelchair or while lying in a bed. The physical therapy device includes a back rest; right and left upper arm rests coupled to the back rest by a first connector; and right and left lower arm rests coupled to the right and left upper arm rests, respectively, by a second connector. Each lower arm rest comprises a handle. Each upper arm rest is configured to move towards the back rest at the first connector to fold flush against the back rest. The physical therapy device further comprises an extender coupled to the back rest; right and left upper leg units coupled to the extender by a third connector; and right and left lower leg units coupled to the right and left upper leg units, respectively, by a fourth connector. Each lower leg unit comprises a stirrup. | 2014-07-17 |
20140200125 | Bed Exercise Apparatus - An exercise apparatus that may be used in a bed, primarily for stretching and resistance exercises. The exercise apparatus may be configured with a lower frame and an upper frame. The lower frame is disposed between and connected to a bed frame and a headboard. The upper frame is connected to the lower frame and has exercise equipment attachment couplers. | 2014-07-17 |
20140200126 | MACHINE TOOL HAVING A MACHINE MAGAZINE AND A BACKGROUND MAGAZINE - In a machine tool having at least one tool spindle which is displaceable in relation to a device for holding workpieces in at least one of three spatial directions and in which the tools (W | 2014-07-17 |
20140200127 | System for Producing Packaging Cushioning - A system for producing packaging cushioning generally includes a cushion conversion machine and a supply structure for a stack of fan-folded sheet stock material. The structure is positioned relative to the machine to supply thereto the fan-folded sheet stock material for conversion thereof into packaging cushioning, and includes an inclined, load-bearing support. The load-bearing support includes a base and a riser extending upwardly from the base, the base and the riser being structured and arranged to cooperatively accommodate the stack of fan-folded sheet stock material such that the sheet stock material is supplied to the cushion conversion machine from a top of the stack and a bottom of the stack is supported by the base. The riser is inclined at an angle relative to vertical such that the stack of fan-folded sheet stock material is also inclined at the angle, whereby, the stack is urged against the riser by force of gravity. | 2014-07-17 |
20140200128 | Centrifuge - A centrifuge, in particular a separator, includes a rotatable centrifuge drum with a vertical axis of rotation and a non-rotatable fixed housing with a hood and preferably a solids collector. In the centrifuge, the housing, in particular the fixed hood and/or at least one other part of the housing, have at least one first inner wall and a first outer wall which delimit a first cavity. The cavity is at least partly filled with damping/insulation agents that are solid at a process or ambient temperature. A coolant that has a fluid form at a process and/or ambient temperature can be introduced into the first cavity filled with the solid damping/insulation agents. | 2014-07-17 |
20140200129 | DENTAL RESTORATION, METHOD FOR PRODUCTION THEREOF AND GLASS CERAMIC - The invention relates to glass ceramics, which show high strength, high translucency, high chemical stability and which are still mechanically processible. The invention further refers to a method for producing a dental restoration comprising such glass or glass ceramic as well as the dental restoration itself. | 2014-07-17 |
20140200130 | METHODS OF FORMING CERAMIC MATRIX COMPOSITE STRUCTURES, AND RELATED SYSTEMS, APPARATUSES, AND CERAMIC MATRIX COMPOSITE STRUCTURES - A method of forming a ceramic matrix composite structure. The method comprises forming at least one prepregged composite material comprising a ceramic fiber preform and a pre-ceramic matrix slurry. The at least one prepregged composite material is placed over at least one surface of a tool using an advanced fiber placement apparatus to form an at least partially uncured composite material structure. The at least partially uncured composite material structure is exposed at least to elevated temperatures to convert the at least partially uncured composite material structure into a ceramic matrix composite structure. A system for forming a ceramic matrix composite structure, an advanced fiber placement apparatus, and a ceramic matrix composite structure are also described. | 2014-07-17 |
20140200131 | Si3N4 INSULATOR MATERIAL FOR CORONA DISCHARGE IGNITER SYSTEMS - A silicon nitride material is disclosed which has properties beneficial for efficient operation of a corona discharge igniter system in an internal combustion gas engine. | 2014-07-17 |
20140200132 | MEMBER COVERED WITH HARD COATING - A member covered with a hard coating according to the present invention has a hard coating which has excellent erosion resistance, a hardness (H) of 20 GPa or more as measured using a nano indenter and a ratio of the hardness (H) to a Young's modulus (E) (i.e., H/E) of 0.06 or more, and comprises Ti and/or Cr, Al and N, wherein the total amount of Ti and Cr relative to the total amount of elements other than non-metal elements in the coating is 0.1 to 0.6 inclusive in terms of atomic ratio and the amount of Al relative to the total amount of the elements other than the non-metal elements in the coating is 0.4 to 0.7 inclusive in terms of atomic ratio. | 2014-07-17 |
20140200133 | CORE-SHELL TYPE METAL NANOPARTICLES AND METHOD FOR PRODUCING THE SAME - The present invention provides core-shell type metal nanoparticles having a high surface coverage of the core portion with the shell portion, and a method for producing the same. Disclosed is core-shell type metal nanoparticles comprising a core portion comprising a core metal material and a shell portion covering the core portion, wherein the core portion substantially has no {100} plane of the core metal material on the surface thereof. | 2014-07-17 |
20140200134 | Anthranilamide Compounds and their use as Pesticides - The present invention relates to anthranilamide compounds and the stereoisomers, salts, tautomers and N-oxides thereof and to compositions comprising the same. The invention also relates to the use of the anthranilamide compounds or of the compositions comprising such compounds for combating invertebrate pests. Furthermore, the invention relates to methods of applying such compounds. | 2014-07-17 |
20140200135 | Carbamoylmethoxy- and carbamoylmethylthio- and carbamoylmethylamino benzamides for combating invertebrate pests - The present invention relates to substituted carbamoylmethoxy and carbamoylmethylthio benzamide compounds and the stereoisomers, salts, tautomers and N-oxides thereof and to compositions comprising the same. The invention also relates to the use of the carbamoylmethoxy- and carbamoylmethylthio-benzamide compounds or of the compositions comprising such compounds for combating invertebrate pests. Furthermore, the invention relates to methods of applying such compounds. | 2014-07-17 |
20140200136 | Agricultural mixtures comprising arylquinazolinone compounds - The present invention relates to pesticidal mixtures comprising as active compounds | 2014-07-17 |
20140200137 | TREATMENT OF STORED TUBERS WITH COMPOSITIONS OF ALKYL NAPHTHALENES AND HIGHER ALCOHOLS - A method and composition of treating post-harvest tubers with a higher alcohol and a lower alkyl naphthalene to suppress sprouting. | 2014-07-17 |
20140200138 | MICRO-COLLOIDAL SILICIC ACID / BORIC ACID COMPOSITION AND A METHOD OF PREPARING A BIOENHANCING SOLUTION AND POWDER - The present invention provides a composition comprising an acidified aqueous solution of (1) micro colloidal silicic acid, (2) boric acid, and (3) a water absorbing additive, having a pH value of equal to or less than 1, wherein the micro colloidal silicic acid has particle sizes in the range of 1-8 nm, especially in the range of 1.5-6 nm. The invention also provides a particulate product obtainable by the method according to claim | 2014-07-17 |
20140200139 | HIGH RESIDUAL EFFECT AND LOW OFF-SITE MOVEMENT AUXIN HERBICIDE FORMULATIONS - The present invention generally relates to high residual effect and/or low off-site movement anionic herbicide formulations and, more particularly, auxin herbicide formulations. Generally, the formulations of the present invention include an anionic herbicide (e.g., an auxin herbicide), a particulate sorbent (e.g., silica), a cationic surfactant, and water. | 2014-07-17 |
20140200140 | METHOD OF CONTROLLING PESTS - The present invention relates to a method of controlling weeds in a crop field, the method including treating the crop field with crystal of flumioxazin described in the specification, before sowing or planting, at the same time of sowing or planting, or after sowing or planting crop seeds or vegetative organs such as tubers, bulbs, or stem fragments which are treated with one or more compounds selected from the following group B;
| 2014-07-17 |
20140200141 | HERBICIDAL FORMULATION - A capsule suspension formulation comprising microencapsulated pendimethalin comprising a herbicidally effective amount of pendimethalin being encapsulated within a polymeric wall, said polymeric wall being in-situ formed by an interfacial polymerization reaction occurring between a first phase dispersed in a second phase, at least one of said first and second phases being characterized in comprising a pre-defined amount of at least one alkali or alkaline earth metal salt of an organic acid; and a herbicidally effective amount of a second herbicide. | 2014-07-17 |
20140200142 | TREATMENT OF STORED TUBERS WITH AEROSOLS OF HIGHER ALCOHOLS - A method and composition of treating post-harvest tubers with a higher alcohol as a thermofogged aerosol to suppress sprouting is disclosed. | 2014-07-17 |
20140200143 | LOW-CONCENTRATION PHYTOTOXIC MICRONUTRIENT COMPOUNDS FOR SELECTIVE CONTROL OF INVASIVE PLANT SPECIES - This invention provides low-dose, low-concentration formulations of phytotoxic trace inorganic compounds for use in methods and systems for selectively and effectively controlling invasive plants. | 2014-07-17 |
20140200144 | TREATMENT OF CROPS WITH A LOWER ALKYL NAPHTHALENE TO ALTER CELL CYCLE AND WATER REGULATION - The instant invention relates to identification of certain genes in potatoes, which are activated by treatment of said potatoes with a preselected dosage of a lower alkyl naphthalene, especially 1,4 dimethyl naphthalene. The activation of these genes produces a dormancy-like state in said potatoes. Particular embodiments relate to the identification of dehydration-resistant genes in said potatoes, which were also activated by said treatment with a lower alkyl naphthalene, such as 1,4 dimethyl naphthalene. | 2014-07-17 |
20140200145 | METHOD OF METABOLIC EVOLUTION - The invention relates to a method for metabolic evolution of a variant of a natural small aromatic molecule product of a metabolic pathway, by somatic in vivo assembly and recombination of said metabolic pathway employing a gene mosaic of at least one gene A, which comprises a) in a single step procedure (i) transforming a cell with at least one gene A having a sequence homology of less than 99.5% to another gene to be recombined that is an integral part of the cell genome or presented in the framework of a genetic construct, (ii) recombining said genes, (iii) generating a gene mosaic of the genes at an integration site of a target genome, wherein said at least one gene A has a single flanking target sequence either at the 5′ end or 3′ end anchoring to the 5′ or 3′ end of said integration site, (iv) recombining eventual further genes of said metabolic pathway, and b) selecting clones comprising said gene mosaic and said eventual further genes capable of expressing said variant, methods of preparing a library of cells producing variants of natural small aromatic molecule products of a metabolic pathway, the libraries so produced and used to prepare said variants. | 2014-07-17 |
20140200146 | Methods of Amplifying Whole Genome of a Single Cell - Methods and compositions for amplifying the whole genome of a single cell are provided. | 2014-07-17 |
20140200147 | Methods and Systems for Genetic Analysis - This disclosure provides systems and methods for sample processing and data analysis. Sample processing may include nucleic acid sample processing and subsequent sequencing. Some or all of a nucleic acid sample may be sequenced to provide sequence information, which may be stored or otherwise maintained in an electronic storage location. The sequence information may be analyzed with the aid of a computer processor, and the analyzed sequence information may be stored in an electronic storage location that may include a pool or collection of sequence information and analyzed sequence information generated from the nucleic acid sample. Methods and systems of the present disclosure can be used, for example, for the analysis of a nucleic acid sample, for producing one or more libraries, and for producing biomedical reports. Methods and systems of the disclosure can aid in the diagnosis, monitoring, treatment, and prevention of one or more diseases and conditions. | 2014-07-17 |
20140200148 | Apparatuses, Methods, Computer Program Products, And Kits for Hi-Throughput Glycan Analysis - An apparatus for glycan analysis is disclosed. The apparatus includes a plurality of loading wells adapted to receive a plurality of samples; a plurality of capillaries arranged in correspondence with the loading wells, each of the capillaries including a first portion including a stacking gel and a second portion including a resolving gel; and a plurality of eluting wells arranged in correspondence with the capillaries and adapted to receive a portion of the samples having traversed the capillaries. | 2014-07-17 |
20140200149 | Methods and compositions for identification of source of microbial contamination in a sample - Herein are described 1058 different bacterial taxa that were unique to either human, grazing mammal, or bird fecal wastes. These identified taxa can serve as specific identifier taxa for these sources in environmental waters. Two field tests in marine waters demonstrate the capacity of phylogenetic microarray analysis to track multiple sources with one test. | 2014-07-17 |
20140200150 | BIOMARKERS - The invention relates to a method of differentially diagnosing schizophrenia, bipolar disorder and major depressive disorder. | 2014-07-17 |
20140200151 | BIOMARKERS - The invention relates to a method of differential diagnosis of schizophrenia or other psychotic disorder from a further psychiatric disorder. | 2014-07-17 |
20140200152 | METHOD FOR SCREENING ANTI-LIGAND LIBRARIES FOR IDENTIFYING ANTI-LIGANDS SPECIFIC FOR DIFFERENTIALLY AND INFREQUENTLY EXPRESSED LIGANDS - The present invention relates to screening methods and, in particular, to methods of screening anti-ligand libraries for identifying anti-ligands specific for differentially and/or infrequently expressed ligands. The method comprises the steps of providing a library of anti-ligands; providing a first subtractor ligand; providing a second target ligand; determining the amount of the first and second target ligands using one or more equations derived from the universal law of mass action; providing the determined amount of a first subtractor ligand; providing the determined amount of a second target ligand; providing separation means capable of use to isolate anti-ligand bound to the second target ligand from anti-ligand bound to the first subtractor ligand; exposing the library of to the first and second target ligands to permit binding of anti-ligands to ligands; and using the separation means to isolate the anti-ligand bound to second target ligand. | 2014-07-17 |
20140200153 | METHODS OF DETECTING LUNG CANCER - Methods of lung cancer in a sample from a patient are provided. Methods of detecting changes in expression of one or more target RNAs associated with lung cancer are also provided. Compositions and kits are also provided. | 2014-07-17 |
20140200154 | LOW-COST POINT-OF-CARE ASSAY DEVICE - The present disclosure provides methods and systems for analyzing a liquid sample. A micro-fluidic device to perform an assay of a liquid sample is described that includes a sample application site and a vent outlet in fluid communication with the capillary channel. A cap is provided that is configured to seal both the vent outlet and the sample application site in a shared volume and separate from an outside environment. | 2014-07-17 |
20140200155 | Prognostic marker for endometrial carcinoma - The present invention relates to a method for diagnosing or determining the status of endometrial carcinoma in an individual afflicted with or suspected to be afflicted with endometrial carcinoma based on the phosphorylated stathmin compound whereby said stathmin is phosphorylated at position Serine 38. Moreover, the present invention relates to a method for evaluating the probability of survival, the clinical outcome or the treatment course of an individual afflicted with or suspected to be afflicted with endometrial carcinoma. In another aspect, the present invention relates to the stratification of the therapeutic regimen of an individual with endometrial carcinoma. In particular, the present invention provides a method for diagnosing or identifying endomentrial carcinoma with high grade aggressive phenotype, in particular, having low response and susceptibility to chemotherapeutic regimen, in particular, with respect to microtubule stabilization based regimen including treatment with taxanes. Moreover, the present invention relates to a kit for use in any of the above-referenced methods comprising means for determining the level or amount of phosphorylated pStathmin(S38) as well as assays for conducting the method according to the present invention. In one embodiment, the methods according to the present invention include the combined determination of stathmin and phosphorylated stathmin (pStathmin(S38)). | 2014-07-17 |
20140200156 | GENES INDUCING AGONISTIC EFFECTS BY ANTI-C-MET ANTIBODY TREATMENT AND DRUG SCREENING METHOD USING THE GENES - Biomarkers for screening drugs reducing side effects of anti-c-Met antibodies and a method of screening using the biomarkers, and more particularly, biomarkers commonly enhancing or reducing gene expression and a method of screening anti-c-Met antibodies having reduced side effects using the biomarkers or a method of screening drugs that reduce side effects of anti-c-Met antibodies. | 2014-07-17 |
20140200157 | Array with Extended Dynamic Range and Associated Method - A system and method of quantitating the concentration of a molecule of interest in one embodiment includes establishing a plurality of test environments at a plurality of test sites, each of the plurality of test environments associated with one of a plurality of response curves, each of the plurality of response curves different from the other of the plurality of response curves, storing a combined response curve resulting from a summation of the plurality of response curves, exposing the plurality of test sites to a sample having a concentration of a molecule of interest, obtaining a plurality of quantitation signals, each of the plurality of quantitation signals associated with one of the plurality of test sites, associating a summation of the plurality of quantitation signals with the stored combined response curve, and generating a signal related to the concentration of the molecule of interest based upon the association. | 2014-07-17 |
20140200158 | MICROARRAY FABRICATION SYSTEM AND METHOD - A microarray is designed capture one or more molecules of interest at each of a plurality of sites on a substrate. The sites comprise base pads, such as polymer base pads, that promote the attachment of the molecules at the sites. The microarray may be made by one or more patterning techniques to create a layout of base pads in a desired pattern. Further, the microarrays may include features to encourage clonality at the sites. | 2014-07-17 |
20140200159 | IDENTIFYING ANTIGEN CLUSTERS FOR MONITORING A GLOBAL STATE OF AN IMMUNE SYSTEM - Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment. | 2014-07-17 |
20140200160 | MOLECULAR-BASED METHOD OF CANCER DIAGNOSIS AND PROGNOSIS - A gene profiling signature for diagnosis and prognosis of cancer patients is disclosed herein. In one embodiment, the gene signature includes 32 or 79 cancer survival factor-associated genes. Thus, provided herein is a method of determining the prognosis of a subject with a tumor by detecting expression of five of more cancer survival factor-associated genes in a tumor sample and comparing expression of the five or more cancer survival factor-associated genes in the tumor sample to a control. In some examples, an increase in expression of ABCF1, CORO1C, DPP3, PREB, UBE3A, and PTDSS1 in a tumor sample compared to a control sample indicates poor prognosis. Further provided are arrays including probes or antibodies specific for a plurality of cancer survival factor-associated genes or proteins. | 2014-07-17 |
20140200161 | METHOD OF PREPARING AN ADDUCT - A method for identifying one or several molecular structure(s) having a high-affinity for a target of interest, the molecular structure(s) each including one nucleotide chain onto which is hybridized at least one PNA-encoded molecule. | 2014-07-17 |
20140200162 | METHOD AND APPARATUS FOR NUCLEIC ACID ANALYSIS - A convenient method for nucleic acid analysis is provided, which enables 1000 or more types of nucleic acid to be analyzed collectively with high comprehensiveness and with a dynamic range of at least four digits. In particular, provided is a very effective analytical method especially for untranslated RNAs and microRNAs, of which the types of target nucleic acids is 10000 or lower. Nucleic acids can be analyzed conveniently and rapidly with high comprehensiveness and quantitative performance at single-molecule sensitivity and resolution by following the steps of: preparing a group of target nucleic acid fragments one molecule at a time and hybridizing the nucleic acid molecules, which have known base sequences and have been labeled with the fluorescence substances, with the group of the target nucleic acid fragments to detect the fluorescence substances labeling the hybridized nucleic acid molecules. | 2014-07-17 |
20140200163 | MULTIPLEXED GENETIC REPORTER ASSAYS AND COMPOSITIONS - The invention provides methods for determining the activity of a plurality of nucleic acid regulatory elements. These methods may facilitate, e.g., the systematic reverse engineering, and optimization of mammalian cis-regulatory elements at high resolution and at a large scale. The method may include integration of multiplexed DNA synthesis and sequencing technologies to generate and quantify the transcriptional regulatory activity of e.g., thousands of arbitrary DNA sequences in parallel in cell-based as says (e.g., mammalian cell based assays). | 2014-07-17 |
20140200164 | SYSTEM FOR DETECTION OF SPACED DROPLETS - System, including methods and apparatus, for detection of spaced droplets. | 2014-07-17 |
20140200165 | NOVEL FAB FRAGMENT LIBRARIES AND METHODS FOR THEIR USE - The present invention provides Fab libraries and methods for using the Fab libraries to obtain antibodies against a target. The Fab library of the invention contains at least 10 | 2014-07-17 |
20140200166 | BIOINFORMATICS SYSTEMS, APPARATUSES, AND METHODS EXECUTED ON AN INTEGRATED CIRCUIT PROCESSING PLATFORM - A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes an integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the integrated circuit connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline. | 2014-07-17 |
20140200167 | FUNCTIONALLY INTEGRATED DEVICE FOR MULTIPLEX GENETIC IDENTIFICATION - A biochip for multiplex genetic identification is disclosed. An biochip for separating and detecting a plurality of DNA fragments includes a set of inputs and chambers for receiving a sample matrix of genetic material and reagents needed to conduct a polymerase chain reaction amplification of the genetic material. The biochip also includes a plurality of separation and detection chambers that physically separate different DNA fragments that have been marked with labels that emit similar colors, thereby enabling the independent detection of the different DNA fragments. | 2014-07-17 |
20140200168 | TREATMENT FLUID CONTAINING A CORROSION INHIBITOR POLYMER OF A CARBOHYDRATE AND QUATERNARY AMINE - A treatment fluid comprises: water; a carboxylate; and a corrosion inhibitor, wherein the corrosion inhibitor is environmentally-friendly, biodegradable, and is a polymer, wherein the polymer comprises a carbohydrate backbone and a quaternary amine functional group; wherein a test fluid consisting essentially of the water, the carboxylate, and the corrosion inhibitor, and in the same proportions as in the treatment fluid, is capable of providing a corrosion weight loss to a metal plate of less than 0.05 pounds per square feet (lb/ft | 2014-07-17 |
20140200169 | High Temperature Oil - The invention relates to novel high temperature oils based on aromatic esters, such as trimellitic acid esters, pryomellitic acid esters, trimesic acid esters or a mixture thereof or derivatives of phloroglucinol and a fully hydrated or a hydrated polyisobutylene or a mixture thereof. | 2014-07-17 |
20140200170 | General purpose vehicle detail cleaning solution - A general purpose detail cleaning solution contains a blend of chemicals in one solution to remove water spots, swirls, dust and fingerprints in existing waxes, polishes and sealants, and revitalize paint. The solution will preferably be available in both squeeze bottles and spray bottles. The user sprays one section of the vehicle at a time, and gently spreads the solution over the entire surface of the vehicle section using a folded microfiber towel. The user then flips over the microfiber towel to reveal a dry section of the towel, and buffs the vehicle section until it is dry. This process is repeated until the entire vehicle has been detail cleaned. | 2014-07-17 |
20140200171 | CLEANING SOLUTION - Disclosed are cleaning solutions. More particularly, non-toxic solutions of base, water, alcohol and detergent, that effectively and surprisingly eliminate contaminating aliphatic acids in aqueous solutions. When present as a foam or even a contaminating film remaining on various parts and surfaces, aliphatic acid contaminants can be present a large and costly problem in manufacturing operations, cleaning tasks, personal hygiene. The need to remove such contaminants arises in a myriad environments and situations, such as during the manufacture of detergents, pharmaceuticals, consumer products, coring and core analysis, manipulation of oils, fuels, fermentation applications, manufacture of emollients, moisturizers, liquors, foods such as seafood, milk, butter and other dairy products, water processing, paper products, tissue culture, reusable clinical equipment, and the like. Presented are cleaning compositions and methods that effectively eliminate and prevent build up of such dangerous and costly contaminants in aqueous solutions. | 2014-07-17 |
20140200172 | Alpha-Amylase Mutants - The invention relates to a novel Termamyl-like alpha-amylase, and Termamyl-like alpha-amylases comprising mutations in two, three, four, five or six regions/positions. The variants have increased thermostability at acidic pH and/or at low Ca | 2014-07-17 |
20140200173 | Stain removing solution - A solution having improved stain removing properties on hard surfaces, carpets and fabrics, that is easier to handle (stored or transported at lower temperatures and less corrosive) and that is environmentally friendly. The stain removing solution includes the following components: a surfactant selected from the group consisting of alcohol ethoxylates, alkyl sulfates, alkyl ether sulfates, alpha olefin sulfonates, alkyl phosphates, alkyl amidopropyl betaines, alkyl betaines, amphoacetates, amphoproprionates, amphosulfonates, amine oxides, alkanolamides, sulfosuccinates, and sultaines, a hydrotrope, and a solvent. The surfactant is preferably an alcohol ethoxylate. The hydrotrope is preferably lauramine oxide. The solvent is preferably a dibasic ester or a glycol ether. The solution may further comprise a diluent, a mild acid, and/or a preservative. A mild acid can be added to lower the pH of the solution. | 2014-07-17 |
20140200174 | PEPTIDE BFP4 FOR PROMOTING OSTEOGENESIS OR VASCULARIZATION AND USE THEREOF - Disclosed are a peptide for promoting osteogenesis and vascularization, and the use thereof. The peptide has a low molecular weight so that it can be economically produced. In addition, it promotes osteoblastic differentiation, thus inducing osteogenesis. Further, the peptide can promote the expression of VEGF, resulting in vascularization. Accordingly, the peptide is useful for the delay of the onset of ischemic diseases and the therapy of ischemic diseases. | 2014-07-17 |
20140200175 | SUPPRESSION OF TOXIN PRODUCTION OF CLOSTRIDIUM DIFFICLE - Disclosed in an embodiment herein is a method of treating symptoms of | 2014-07-17 |
20140200176 | NUTRITIONAL COMPOSITIONS CONTAINING MAGNESIUM THREONATE AND USES THEREOF - The present disclosure relates to nutritional composition(s) comprising a carbohydrate source, a protein source, a fat source and magnesium threonate. Magnesium threonate may provide neurological health benefits when consumed. The disclosure further relates to methods of promoting neurological health by providing a nutritional composition comprising magnesium threonate. Additionally, the disclosure relates to methods of promoting GI tolerance in a pediatric subject by providing a nutritional composition comprising magnesium threonate. | 2014-07-17 |
20140200177 | METHOD OF DETECTION OF OCCULT PANCREATIC BETA CELL DYSFUNCTION IN NORMOGLYCEMIC PATIENTS - This invention relates to a method for detecting the presence of or likelihood of a patient of developing occult pancreatic beta cell dysfunction, and a method for detecting the presence of or likelihood of a patient of developing clinically significant post-prandial hyperglycemia. The methods involve (a) measuring a level of alpha-hydroxybutyrate (AHB) in a single fasting baseline biological sample of the patient; (b) comparing the level of AHB in the single fasting baseline biological sample to a reference AHB level; and (c) determining the presence of or likelihood of developing the disorder in the patient based on the comparison in step (b). An increased AHB level at fasting baseline indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing occult pancreatic beta cell dysfunction. An increased AHB level at fasting baseline and an elevated glucose level of at least about 155 mg/dL at 30 minutes and/or 1 hour indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing clinically significant post-prandial hyperglycemia. | 2014-07-17 |
20140200178 | METHOD OF DETECTION OF CLINICALLY SIGNIFICANT POST-PRANDIAL HYPERGLYCEMIA IN NORMOGLYCEMIC PATIENTS - This invention relates to a method for detecting the presence of or likelihood of a patient of developing occult pancreatic beta cell dysfunction, and a method for detecting the presence of or likelihood of a patient of developing clinically significant post-prandial hyperglycemia. The methods involve (a) measuring a level of alpha-hydroxybutyrate (AHB) in a single fasting baseline biological sample of the patient; (b) comparing the level of AHB in the single fasting baseline biological sample to a reference AHB level; and (c) determining the presence of or likelihood of developing the disorder in the patient based on the comparison in step (b). An increased AHB level at fasting baseline indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing occult pancreatic beta cell dysfunction. An increased AHB level at fasting baseline and an elevated glucose level of at least about 155 mg/dL at 30 minutes and/or 1 hour indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing clinically significant post-prandial hyperglycemia. | 2014-07-17 |
20140200179 | WNT COMPOSITIONS AND METHODS OF USE THEREOF - Wnt compositions and methods for their use are provided. Compositions of the invention comprise fragments of wnt polypeptides having a desired biological activity, which fragments are referred to herein as “mini-wnts”. These compositions and methods find particular use in determining bind to Wnt receptors; inhibiting Wnt signaling in a cell that expresses a Wnt receptor; in delivering a functional moiety to a cell that expresses a Wnt receptor; and as an immunogen for producing Wnt-specific antibodies. | 2014-07-17 |
20140200180 | METHOD FOR PRODUCING PROTEINS IN PICHIA PASTORIS THAT LACK DETECTABLE CROSS BINDING ACTIVITY TO ANTIBODIES AGAINST HOST CELL ANTIGENS - Methods for producing proteins and glycoproteins in | 2014-07-17 |
20140200181 | SYSTEM AND METHOD OF MODELING ERYTHROPOIESIS AND ITS MANAGEMENT - A method of adjusting a patient's undesired hematocrit and/or hemoglobin concentration to a value within a desired range at a predetermined time with an erythropoiesis stimulating agent (ESA) regimen includes obtaining patient parameters required for input into a model for predicting the patient's hematocrit and/or hemoglobin concentration at a predetermined time with a selected ESA administration regimen, and employing the patient parameters and an initially selected EPO administration regimen in the model to predict the patient's hematocrit and/or hemoglobin concentration at the predetermined time with the initially selected ESA administration regimen. Optionally, if the patient's hematocrit and/or hemoglobin concentration is not predicted by the model to be in the desired range at the predetermined time, the method includes employing the model with one or more different ESA administration regimens until the model predicts that the patient's hematocrit and/or hemoglobin concentration will be in the desired range at the predetermined time. The method then includes administering ESA to the patient with an ESA administration regimen predicted to adjust the patient's hematocrit and/or hemoglobin concentration to the desired range at the predetermined time. The method can be implemented in a computer system for adjusting a patient's undesired hematocrit and/or hemoglobin concentration to a desired range at a predetermined time with an erythropoiesis stimulating agent (ESA) regimen. | 2014-07-17 |
20140200182 | METHODS OF ADMINISTERING BONE MORPHOGENETIC PROTEIN COMPOSITIONS - The present invention relates to compositions of bone morphogenetic proteins, particularly solid and liquid formulations of such proteins comprising one or more stabilizing excipients. The invention further provides methods of producing the compositions, kits comprising the compositions and methods of using the compositions in the treatment of diseases of skeletal and non-skeletal tissues. | 2014-07-17 |
20140200183 | TREATMENT OF CARDIAC ARRHYTHMIAS - Compositions of the invention, including compounds that bind to a receptor for a glucagon-like peptide-1, an incretin, a glucagon-like peptide-1 (GLP-1), an exendin, or an agonist, an analog (preferably an agonist analog), a derivative, or a variant of any of aforementioned compounds, are used in the prevention and treatment of arrhythmias associated with cardiac ischemia, cardiac ischemia-perfusion and/or congestive heart failure. The invention relates to both the method and compositions for such treatment. | 2014-07-17 |
20140200184 | Chitinase-3-Like Protein 1 as a Biomarker of Recovery from Kidney Injury - The present invention provides compositions and methods for the detection, treatment, and prevention of a kidney injury. The invention relates to the discovery that chitinase 3-like 1/Brp-39/YKL-40 serves as both a biomarker for the degree of kidney injury and a critical mediator of a reparative response in the kidney. | 2014-07-17 |
20140200185 | CYCLOSPORIN DERIVATIVES FOR TREATING OCULAR AND DERMAL DISEASES AND CONDITIONS - The present invention provides a method for the treatment of ocular or dermal diseases and/or conditions, e.g. an aqueous deficient dry eye state, uveitis or phacoanaphylactic endophthalmitis in an eye, or balanitis, psoriasis, or atopic dermatitis of the skin, said method comprising administering, topically to the eye or the skin, a therapeutically effective amount of a novel cyclosporin A derivative selected from the group consisting of compounds represented by the formula: | 2014-07-17 |
20140200186 | SMALL MOLECULE COMPOSITE SURFACES AS INHIBITORS OF PROTEIN-PROTEIN INTERACTIONS - A method of inhibiting a binding event between a target protein and a binding protein, comprising administering to a cell in vitro an effective amount of a non-naturally occurring bifunctional inhibitor molecule including (a) protein binding moiety, and (b) an effector region, wherein the protein binding moiety binds to a blocking protein, and wherein the effector region binds to the target protein in order to bind the target protein and the blocking protein and prevent access of the binding protein to the target protein. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 2014-07-17 |
20140200187 | Cell-Permeable Peptide Inhibitors of the JNK Signal Transduction Pathway - The present invention refers to protein kinase inhibitors and more specifically to inhibitors of the protein kinase c-Jun amino terminal kinase. Additionally, the present invention provides JNK inhibitor sequences, chimeric peptides, nucleic acids encoding same as well as pharmaceutical compositions for treating pathophysiologies associated with JNK signaling. | 2014-07-17 |
20140200188 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT - Provided are methods for treating Orthomyxoviridue virus infections by administering ribosides, riboside phosphates and prodrugs thereof, of Formula I: | 2014-07-17 |
20140200189 | ARTONI I TO TREAT RESISTANT INFECTIOUS STAPHYLOCOCCUS AUREUS - Artonin I is reported to treat multi-drug resistant | 2014-07-17 |
20140200190 | NOVEL GALACTOSIDE INHIBITORS OF GALECTINS - Compounds having an effect as i.a. galectin inhibitors, to the use of said compounds as a medicament, as well as for the manufacture of a medicament for treatment of disorders relating to the binding of galectin to receptors in a mammal, wherein the galectin is preferably a galectin-3. The novel compounds are defined by the general formula: | 2014-07-17 |