30th week of 2018 patent applcation highlights part 10 |
Patent application number | Title | Published |
20180207283 | DISPERSION COMPRISING AN ESTERIFIED CELLULOSE ETHER - Capsule shells and coatings can be prepared from an aqueous composition comprising a) at least 20 percent, based on the total weight of the aqueous composition, of a dispersed esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, b) from 0.05 to 20 percent of a salt of a fatty acid, based on the weight of the dispersed esterified cellulose ether, and c) from 0.01 to 10 percent of an anionic surfactant comprising a sulfate or sulfonate group, based on the weight of the dispersed esterified cellulose ether. | 2018-07-26 |
20180207284 | FLUORESCENT PRODRUGS - The invention provides a drug conjugate comprising: 1) a therapeutic agent that comprises a phosphate, phosphonate, carboxy, or phosphoramidate group, and 2) a fluorescent group linked to the phosphate, phosphonate, carboxy, or phosphoramidate group to form the corresponding ester and salts thereof. The conjugates are useful for therapy and as probes. The invention also provides therapeutic methods for treating diseases with conjugates of the invention as well as methods for determining optimal dosages of a conjugate or a therapeutic agent for a given patient using a conjugate of the invention | 2018-07-26 |
20180207285 | CELL PENETRATING PEPTIDE INHIBITORS OF p53-MDM2 INTERACTION - Provided are compounds having the Formula I or II: | 2018-07-26 |
20180207286 | CONJUGATES OF A CHOLINESTERASE MOIETY AND A POLYMER - Conjugates of a cholinesterase moiety and one or more nonpeptidic, water-soluble polymers are provided. Typically, the nonpeptidic, water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to a patient. | 2018-07-26 |
20180207287 | TARGETED PEPTIDE CONJUGATES - The present invention relates to the preparation and use of therapeutic compounds for the treatment of diseases at specific subcellular target areas such as specific cellular organelles. In particular, the therapeutic compounds of the invention are specific for modifying enzyme activity within targeted organelles or structures of cells and tissues. Subcellular organelles and structures that may be specifically targeted by compounds of the present invention include lysosomes, autophagasomes, the endoplasmic reticulum, the Golgi complex, peroxisomes, the nucleus, membranes and the mitochondria. | 2018-07-26 |
20180207288 | METHOD FOR TREATING IFNALPHA RELATED CONDITIONS - An immunogenic product including IFNα coupled to a carrier protein molecule is capable to induce in vivo anti-IFNα antibodies and is useful in treating IFNα related conditions. | 2018-07-26 |
20180207289 | A Method for Mitigating Osteoporosis Using Metallic Gold Cluster Molecules - A therapeutic method for mitigating bone loss. This method includes preparing and administering to animals intraperitoneally or orally a therapeutic agent containing metallic gold cluster molecules as an active ingredient. | 2018-07-26 |
20180207290 | ANTI-NKP46 ANTIBODIES, TOXIN CONJUGATES, AND THERAPEUTIC USE OF SAME - An affinity binding moiety comprising an antigen recognition region which comprises complementarity determining region (CDR) amino acid sequences as set forth in heavy chain ordered N to C terminus: SEQ ID NOs: 4, 6 and 8, and light chain ordered N to C terminus: SEQ ID NOs: 12, 14 and 16 is disclosed. A pharmaceutical compositions comprising as an active ingredient the affinity binding moiety is also disclosed. Methods of diagnosing, preventing or treating an autoimmune disease or a cancer associated with an expression of NKp46 are also disclosed. | 2018-07-26 |
20180207291 | ANTI-TUMOUR IMMUNE RESPONSES TO MODIFIED SELF-EPITOPES - The present invention relates to modified citrullinated enolase peptides that can be used as targets for cancer immunotherapy. These peptides can be used as vaccines or as targets for monoclonal antibody (mAb) therapy. Such vaccines or mAbs may be used in the treatment of cancer. | 2018-07-26 |
20180207292 | METHODS FOR TREATING DISORDERS ASSOCIATED WITH ANGIOGENESIS AND NEOVASCULARIZATION - Provided herein are methods and immunoconjugate dimer compositions for the treatment of diseases associated with angiogenesis and neovascularization. In one aspect, the invention relates to a method for treating wet age-related macular degeneration (AMD) in an eye of a patient in need thereof. The method comprises administering to the patient in multiple dosing sessions, a composition comprising an effective amount of an immunoconjugate dimer, wherein the monomer subunits of the dimer each comprises a mutated human factor VIIa (fVIIa) protein conjugated to the human immunoglobulin G1 (IgG1) Fc domain. | 2018-07-26 |
20180207293 | NANOPARTICLES FOR SUSTAINED OPHTHALMIC DRUG DELIVERY AND METHODS OF USE - Disclosed is a method of treating an ocular disorder, comprising contacting the eye of a subject in need thereof with an effective amount of a therapeutic nanoparticle composition, the therapeutic nanoparticle composition comprising (i) at least one population of nanostructures, (ii) a peptide attached to the at least at least one population of nanostructures, (iii) a therapeutic agent useful for the treatment of the ocular disorder attached to the at least one population of nanostructures or to the peptide; and (iv) optionally, a linkage between the at least one population of nanostructures or the peptide and the therapeutic agent. | 2018-07-26 |
20180207294 | NON-ALCOHOLIC FATTY LIVER REGULATING FACTOR 14-3-3 PROTEIN - The present invention relates to the 14-3-3 protein which is a non-alcoholic fatty liver regulating factor. According to the present invention, two isoform proteins of 14-3-3, i.e., 14-3-3β and 14-3-3γ, are different regulating factors for regulating the transcriptional activity of PPARγ | 2018-07-26 |
20180207295 | RNA CONTAINING COMPOSITION FOR TREATMENT OF TUMOR DISEASES - The present invention relates to RNA containing compositions for use in the treatment or prophylaxis of tumor and/or cancer diseases, to a pharmaceutical composition, to a kit and to uses of the RNA containing compositions for the treatment or prophylaxis of tumor and/or cancer diseases. | 2018-07-26 |
20180207296 | Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases - This invention relates to biotechnology, more particularly, to water-soluble polymeric delivery systems for the imaging, evaluation and/or treatment of rheumatoid arthritis and other inflammatory diseases. Using modern MR imaging techniques, the specific accumulation of macromolecules in arthritic joints in adjuvant-induced arthritis in rats is demonstrated. The strong correlation between the uptake and retention of the MR contrast agent labeled polymer with histopathological features of inflammation and local tissue damage demonstrates the practical applications of the macromolecular delivery system of the invention. | 2018-07-26 |
20180207297 | Plastic Containers - The present invention provides a method for the commercial presentation of a solution of gadolinium-DOTA that provides certain advantages over the known methods. | 2018-07-26 |
20180207298 | Chelated PSMA Inhibitors - Compounds as defined herein are provided which are useful in (1) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable diluent; and (3) methods for imaging prostate cancer cells. | 2018-07-26 |
20180207299 | ORGAN PROTECTION IN PSMA-TARGETED RADIONUCLIDE THERAPY OF PROSTATE CANCER - A method of reducing radiation exposure of a non-cancerous tissue of a patient diagnosed with a cancer includes administering to the patient an agent capable of competing for binding sites on a surface of the non-cancerous tissue, provided that the administration is carried out after a waiting period that follows administration of a compound including a radionuclide to the patient, the compound having affinity for both a cancerous tissue and the non-cancerous tissue, and, further provided that the binding sites have an affinity for both the agent and the compound. | 2018-07-26 |
20180207300 | APPARATUS AND METHODS FOR MAINTAINING STERILITY OF A SPECIMEN CONTAINER - An apparatus includes a fluid reservoir, a sterilization member, and a transfer adapter. The sterilization member operably couples to the fluid reservoir. The sterilization member is configured to be transitioned between a first configuration, in which the sterilization member obstructs an inlet surface of the fluid reservoir and maintains the inlet surface in a substantially sterile environment, and a second configuration, in which the inlet surface is unobstructed. The transfer adapter is configured to be placed in fluid communication with a portion of a patient. The transfer adapter is configured to move relative to the sterilization member from a first position to a second position such that a surface of the transfer adapter contacts the sterilization member to transition the sterilization member to the second configuration. The fluid reservoir is placed in fluid communication with the transfer adapter when the transfer adapter is in the second position. | 2018-07-26 |
20180207301 | ELECTROCHEMICAL REDUCTION OR PREVENTION OF INFECTIONS - Treatment systems, devices, articles, and associated methods of operation for treating open wounds are disclosed herein. In one embodiment, a method includes applying a first material and a second material to be in contact with a surface of the open wound having a water content at the surface and applying a voltage differential to the first and second materials, thereby producing hydrogen peroxide (H2O2) at the surface via an electrochemical reaction between oxygen (O2) in air and water (H2O) in the water content at the surface. The voltage differential is calibrated to correspond to a concentration of the produced hydrogen peroxide in the water content effective in reducing or preventing a bacterial infection at the surface of the open wound. | 2018-07-26 |
20180207302 | Methods and Devices for Sanitation, Disinfection and Sterilization - The present invention relates to methods and devices for diminishing microbes. The invention provides methods and devices to sanitize, disinfect and sterilize areas, spaces, surfaces and items as well as to sanitize human skin. The methods and devices will be of major importance to the healthcare industry and to other industries or physical environments that require sanitizing, disinfecting or sterilizing. The methods comprise the use of near infrared light (NIR), UV, violet and blue emitting LED elements as well as OLED (Organic Light-Emitting Diodes) as a stand-alone technology. Optionally the system may be used in combination with ozone and ionized silver. | 2018-07-26 |
20180207303 | UV DEVICES, SYSTEMS, AND METHODS OF MAKING AND USE - Provided herein are portable ultraviolet (UV) devices, systems, and methods of use and manufacturing same. Methods of use include methods for UV disinfection and sterilization, more specifically, methods for UV disinfection and sterilization of a container, a room, a space or a defined environment. The portable UV devices, systems and methods are particularly useful for the UV disinfection and sterilization of a container, a room, a space or defined environment used in the food, beverage and dairy industry and in the process of fermentation for an alcoholic beverage. Provided are also portable UV devices, systems, and methods for inhibiting the growth of one or more species of microorganisms present in a container, a room, a space or a defined environment, preferably for inhibiting the growth of one or more species of microorganisms present on an interior surface of a container, a room, a space or a defined environment. | 2018-07-26 |
20180207304 | MEDICAL CONDUIT - A catheter which is one mode of a medical conduit of the present invention is placed inside a human body from the outside of the human body through human tissue. The catheter has a light introducing portion. The light introducing portion is provided on an outer wall surface of the catheter located on the outside-of-human-body side, and allows at least a part of ultraviolet light irradiated from the outside of the catheter to be totally reflected at an inner wall surface of the catheter toward the inside-of-human-body side. | 2018-07-26 |
20180207305 | CLEAN IN PLACE ICE MAKING SYSTEM - An ice machine prevents micro-organism growth by utilizing a clean-in-place process. The ice making process of the ice making machine is turned OFF, and then ozonated water, from an ozonated water generation system, is pumped into a distribution system, within the ice making machine so that the ozonated water is sprayed onto surfaces of the ice making machine which are susceptible to micro-organism growth and/or scale. Exposing the surfaces to ozonated water kills the micro-organisms and rinses the dead micro-organisms out of the ice making machine. | 2018-07-26 |
20180207306 | METHOD FOR LIQUID DETECTION AND DRYING - Liquid water detection in a sterilization chamber that can distinguish liquid water from material in the load that is outgassing and can dry the liquid, is independent of the vacuum pump and chamber leak rate, and that is capable of detecting small amounts of liquid and drying the liquid without freezing the liquid in the process is achieved by monitoring conditions in the chamber at two different pressures, one above the boiling point of water and another below the boiling point of water at a given load temperature. | 2018-07-26 |
20180207307 | Disinfecting Articles With Ozone - The present invention extends to methods, apparatus, and systems for disinfecting articles with ozone. Aspects of the invention use increased concentrations ozone in sealed, confined volumes, such as, for example, carts, lockers, cabinets, etc. to disinfect or sterilize medical articles. A medical article is placed in a confined volume. The confined volume is sealed so that the atmosphere inside the sealed, confined volume is isolated from the external atmosphere. The concentration of ozone in the sealed, confined volume is rapidly increased to a threshold concentration. At the threshold ozone concentration, the medical article can be disinfection or sterilized in a reduce amount of time. When disinfection or sterilization is complete, the concentration of ozone in the sealed, confined volume is rapidly reduced to a safe level. The sealed, confined volume is unsealed. The disinfected or sterilized medical article can be removed from the confined volume. | 2018-07-26 |
20180207308 | MEDICAL DEVICE PACKAGING CONTAINER, MEDICAL DEVICE PACKAGING, AND OUTER CYLINDER PACKAGING FOR PRE-FILLED SYRINGES - A medical device packaging container housing a medical device and being configured for high pressure steam sterilization includes: a main body part that includes an open upper face part and a bottom part, wherein the upper face part includes a lid member fixing part for attachment of a peelable sheet-shaped lid member; and a water dispersion part disposed in a peripheral part of the bottom part along a side wall of the main body part, and being configured to disperse water stored in the peripheral part. | 2018-07-26 |
20180207309 | WATER-BASED FRAGRANCE COMPOSITION, FRAGRANCE DELIVERY DEVICE, AND METHOD OF PROVIDING A LONG-LASTING SCENT - A water-based fragrance composition comprises at least about 67 wt % water and between about 5 and about 17 wt % of a first organic solvent, wherein the first organic solvent comprises one or more relatively volatile, water soluble, low molecular weight organic compound(s) having a boiling point less than about 100° C. The water-based fragrance composition further comprises about 5 wt % or less of at least one fragrance formulation and between about 0 and about 22 wt % of a second organic solvent, wherein the second organic solvent comprises one or more moderately volatile, water soluble organic compound(s) having a boiling point greater than or equal to about 100° C. and less than or equal to about 300° C. | 2018-07-26 |
20180207310 | Moisture and Odour Removing Insert - A pod for removing odor and moisture from a substantially confined area has deodorant and moisture adsorbing properties to counteract unpleasant odours, especially odours due to microbial growth. The pod is removably insertable into footwear, gloves, skates, lockers, sports gear, workout gear or any gear or enclosure. The pod has a fabric pouch with anti-microbial properties and contains fragrance-releasing particles and desiccant granules. The moisture adsorbing properties of the pod may be thermally rechargeable. The pods may be attached to other pods in use. | 2018-07-26 |
20180207311 | ELECTRONIC APPARATUS HAVING PHOTOCATALYTIC FILTER - An electronic apparatus capable of controlling the air purification performance of a photocatalytic filter according to an air volume of a blowing fan and a concentration of a specific gas. An electronic apparatus having a deodorizing performance recovery function of a photocatalytic filter. The electronic apparatus includes a blowing fan, a filter apparatus configured to purify air introduced by the blowing fan and a controller configured to adjust a current applied to the filter apparatus, wherein the filter apparatus comprises a light emitting module to which a plurality of light emitting portions configured to output ultraviolet light is mounted, a photocatalytic filter provided to face the light emitting portion and a support frame configured to support the light emitting module and the photocatalytic filter to be apart from each other by a predetermined distance. | 2018-07-26 |
20180207312 | Filtering Apparatus - A filtering apparatus includes a filter with meshes having a periphery enclosed by a metal frame, an antibacterial material layer formed on the filter, a negative ions generator stretching into the filter for generating negative oxygen ions, and an electrode plate disposed on the metal frame. The metal frame is affected by the electrode plate to produce a high voltage electric field, thereby activating the antibacterial material layer under a piezoelectric effect to release more negative oxygen ions and silver ions. The negative oxygen ions and the silver ions collide together within the filter and become finer, thereby absorbing smelly odor passing through the filter to the maximum extent, purifying air, destroying germs, and promoting the air quality of the environment. | 2018-07-26 |
20180207313 | THERMOPLASTIC ARTICLE WITH ACTIVE AGENT - An extruded water-soluble article is made from homogeneous material that includes a water-soluble polymer having an extrusion temperature of 50 to 150° C. This relatively low extrusion temperature is compatible with actives that would otherwise be destroyed in a high temperature extrusion process. The article further includes between 0.1% to 50% by weight of an active agent. Potential active agents include, isothiazolone, alkyl dimethyl ammonium chloride, a triazine, 2-thiocyanomethylthio benzothiazol, methylene bis thiocyanate, acrolein, dodecylguanidine hydrochloride, a chlorophenol, a quaternary ammonium salt, gluteraldehyde, a dithiocarbamate, 2-mercatobenzothiazole, para-chloro-meta-xylenol, silver-based compounds, chlorohexidine, polyhexamthylene biguanide, a n-halamine, triclosan, a phospholipid, an alpha hydroxyl acid, 2,2-dibromo-3-nitrilopropionamide, 2-bromo-2-nitro-1,3-propanediol, iodine, bromine, hydrogen peroxide, chlorine dioxide, ozone, a botanical oil, a botanical extract, chlorine, sodium hypochlorite, farnasol, inulin, prebiotics, benzalkonium chloride, and combinations thereof. The article may be in the form of a film, and in one potential use, be disposed in an absorbent article. | 2018-07-26 |
20180207314 | FASCIA FIBROUS COMPOSITIONS AND METHODS FOR THEIR USE AND MANUFACTURE - Embodiments of the present technology may permit for native, intact, natural, human-derived, or allograft-derived fibers to be used as threads for suturing. Embodiments may include a thread for suturing. The thread may include a first portion, which includes a fascia fiber. The first portion may have a first end that includes the fascia fiber. The thread may also include a second portion including a non-human-derived fiber. The second portion may have a first end that includes the non-human-derived fiber. The first end of the second portion may be attached to the first end of the first portion. Embodiments may include a method of forming a thread. The method may include attaching a first end of a fascia fiber to a first end of a first non-human-derived fiber. The method may also include attaching a second end of the fascia fiber to a first end of a second non-human-derived fiber. | 2018-07-26 |
20180207315 | SPATIAL CONTROL OF ADDITIVES BY HIGH TEMPERATURE - Provided is a method of making a polymeric material with a spatially controlled distribution of one or more additives including the steps of blending the one or more additives with a polymeric material, consolidating the polymeric material, heating at least a portion of at least one surface of the consolidated additive-blended polymeric material, and cooling the heated consolidated additive-blended polymeric material, thereby forming a polymeric material with a spatially controlled distribution of additive. | 2018-07-26 |
20180207316 | METHODS AND COLLAGEN PRODUCTS FOR TISSUE REPAIR - Methods and devices for the repair of articular tissue using collagen material are provided. Compositions of collagen material and related kits are also provided. | 2018-07-26 |
20180207317 | METHOD FOR FUSION OF FRACTURED OR VOIDED STERNUM POST STERNOTOMY - Disclosed herein are improved surgical techniques for repairing bone defects in a sternum during a sternotomy procedure and implants adapted for such techniques. In an exemplary embodiment, provided is a fusion strip made of an osteoconductive material and of a dimension that is especially adapted for improved repair of sternal bone defects. | 2018-07-26 |
20180207318 | TISSUE DECELLULARIZATION METHODS - Provided herein are methods of producing an acellular tissue product wherein the method can include the step of inducing apoptosis and washing the tissue after induction of apoptosis with a tonic solution. Also provided herein are acellular tissue products produced by the methods provided herein and methods of administering the acellular tissue products to a subject in need thereof. | 2018-07-26 |
20180207319 | HYDROGEL FOR CARTILAGE TISSUE REGENERATION - A method for cartilage tissue engineering including fabricating a nanocomposite, injecting the nanocomposite into a defect site of cartilage, and forming a hydrogel in the defect site of the cartilage using a sol-gel transition responsive to increasing temperature of the nanocomposite from room temperature to 37° C. Fabricating a nanocomposite includes forming an activated copolymer by functionalizing a copolymer, forming a conjugated copolymer by grafting the activated copolymer to a polysaccharide, forming a protein-conjugated copolymer by crosslinking a protein with the conjugated copolymer, forming the nanocomposite by adding a plurality of nanoparticles to the protein-conjugated copolymer. | 2018-07-26 |
20180207320 | IMPLANT WITH AN BIOACTIVE COATING AND METHOD FOR PROVIDING THE SAME - The present invention relates to an implant having a surface comprising a coating on at least a portion of the surface of the implant, wherein the coating comprises at least two coating layers of bioactive compounds adjacent to each other, obtainable in a process comprising the following steps: providing an implant with a surface, providing a first suspension comprising at least one first bioactive compound in a first solvent, wherein the first bioactive compound is non-soluble or partially soluble in the first solvent, applying said first suspension comprising the at least one first bioactive compound onto at least a part of the implant surface forming a first coating layer; drying the first coating layer, providing a second solution comprising at least one second bioactive compound in a second solvent, wherein the second bioactive compound is soluble or readily soluble in the second solvent; applying said second solution comprising the at least one second bioactive compound onto the first coating layer forming a second coating layer, and drying the second coating layer. | 2018-07-26 |
20180207321 | DRUG ELUTING MEDICAL DEVICE - The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom. | 2018-07-26 |
20180207322 | Biocompatible Self-Lubricating Polymer Compositions and Their Use in Medical and Surgical Devices - The invention comprises self-lubricating polymer compositions that are especially useful in medical devices and valves and gaskets of medical devices. In a preferred embodiment, the polymer compositions comprise a thermosetting or thermoplastic silicone elastomer in combination with a lubricity enhancing polyfluoropolyether fluid or hydrocarbon-based synthetic oil. In other preferred embodiments, the polymer compositions contain only biocompatible components. The improved anti-friction properties of the self-lubricating polymers can be demonstrated over a course of insertion and withdrawal cycles, where conventional polymers have changing and mostly increasing force required for each insertion and withdrawal, while the polymer compositions of the invention remain stable. | 2018-07-26 |
20180207323 | MEDICAL PRODUCTS AND METHODS CONFIGURED FOR CONTROLLED RELEASE OF NITRIC OXIDE - The disclosure concerns various medical devices implemented to provide a nitric oxide rich environment for anti-microbial or anti-thrombogenic benefits. The medical device generally includes a nitric oxide donor material that is contained within a sealed cavity, and a transport medium that defines and captivates the entirety of the cavity, wherein the transport medium is permeable to both water and nitric oxide. As the nitric oxide donor material becomes saturated with water from the surrounding tissue or fluids, nitric oxide is chemically released, and the resulting nitric oxide is communicated through the transport medium to a treatment site for anti-microbial and anti-thrombogenic benefits. | 2018-07-26 |
20180207324 | SYRINGE INCLUDING DIFFERENT MATERIALS - A syringe includes a syringe body, a syringe cone having a distal opening, and a connection arranged in the region of the syringe cone, wherein the syringe body includes a first material and the connection includes a second material, and wherein the first material is different from the second material and the second material is a softer material than the first material. | 2018-07-26 |
20180207325 | NOVEL COATINGS FOR MEDICAL DEVICES - The present invention is directed to improved coatings and coating methods for medical devices. | 2018-07-26 |
20180207326 | Coated endovascular devices - The present disclosure relates to the field of medical treatment. More particularly, the current invention delivers medication via a coating via a hydrogel infused with pharmaceutical compounds into the bloodstream to promote the supply to the distal vascular bed beyond the stent. The present invention uses in a preferred embodiment a stent with a thin coating of biodegradable or non-biodegradable hydrogel designed to ameliorate or eliminate vasospasms or thromboses, or to treat cancer, which hydrogel may optionally be impregnated with pharmaceutical compounds. The present invention also teaches the use of thin hydrogel coatings to ameliorate treatment related difficulties. | 2018-07-26 |
20180207327 | Hybrid Implant System and Manufacturing Method Therefor - The present disclosure discloses a hybrid implant system for fixing and repairing orthopedic fracture and a manufacturing method therefor. The hybrid implant system comprises an implant body having holes on both ends and a locking part configured for attaching the implant body to a broken bone through the holes. The hybrid implant system further comprises a healing assembly made from a material promoting healing of the bone. The implant body has at least one window on a side, the at least one window is aligned with a broken location of the bone, and the healing assembly is inserted into the window in a self-locking manner towards an interior of the implant body. | 2018-07-26 |
20180207328 | Implantable Compositions for Pain Management - The invention includes an implantable composition for management of pain in animals. The composition includes one or more active ingredients, a biocompatible polymer based drug delivery matrix, and other compounds to facilitate composition manufacture and durability. The composition disclosed herein is administered as a veterinary implant device. The implant is inserted subcutaneously into a patient and is designed to function in vivo for prolonged periods of time ranging from multiple weeks to months or even years. Accordingly, the composition must provide a constant release of one or more active ingredients over an extended period of time. To enable combination therapy for pain management, the composition may also include one or more layers of active ingredients seeded into one or more drug delivery systems. Multiple compositions having one or more layers loaded with different active ingredients may also be used in combination therapies. | 2018-07-26 |
20180207329 | MANUALLY-ACTUATED REDUCED PRESSURE TREATMENT SYSTEM WITH AUDIBLE LEAK INDICATOR - Illustrative embodiments of new and useful systems and methods for reduced-pressure therapy are described. One example embodiment is a manually-actuated pump for applying reduced-pressure therapy. The pump generally comprises a charging chamber, a regulated chamber, and a regulator passage between the charging chamber and the regulated chamber. A valve body controls fluid communication through the regulator passage, and a regulator spring may be engaged with the valve body to bias the valve body against a differential between a pressure in the regulated chamber and an ambient pressure. The regulator passage may have a bore size adapted deflect the valve body to cause an audible indication of a leak. | 2018-07-26 |
20180207330 | ON-DEMAND FLUIDICS SYSTEM CONTROL BASED ON FREQUENCY-DOMAIN PROCESSING - Frequency-domain signal processing of pressure sensor signals and/or flow signals is used to provide on-demand control of a multi-component fluidic system. An example method, implemented in a phacoemulsification system comprises receiving a signal from each of one or more sensors, the one or more sensors comprising at least one pressure sensor, and converting each of one or more of the received signals, including at least one signal from a pressure sensor, to a frequency-domain representation of the received signal. The method further comprises identifying, based on the frequency-domain representations of received signals, at least one event from a set of predetermined events, and controlling one or more fluid control devices, responsive to the identifying. | 2018-07-26 |
20180207331 | CHAMBER FOR THE COLLECTION OF LIPOASPIRATE - Embodiments of the present invention disclose a device for collection and purification of adipose tissue and methods of making and using the same. | 2018-07-26 |
20180207332 | MEDICAL DEVICES AND RELATED METHODS - A medical system includes an irrigation system including an irrigation bag containing irrigation fluid and an irrigation line, and a medical device with at least two internal lumens connecting at least two ports on a handle to a distal end of the medical device. The medical system also includes a suction system including a suction source, a waste container, and a suction line, and a controller that controls at least one of the irrigation system and the suction system. The irrigation line is coupled to a first port, and the suction line is coupled to a second port. | 2018-07-26 |
20180207333 | RELEASABLY SEALABLE WOUND DRESSING FOR NPWT - A therapeutic device having a hydrogel drape and a method of treatment using the same. | 2018-07-26 |
20180207334 | INTRACARDIAC PUMPING DEVICE - The invention relates to an intercardiac pump device comprising a pump ( | 2018-07-26 |
20180207335 | CARDIAC ASSIST DEVICE - A cardiac pump and an assist system is provided that increases blood ejection from a compromised heart. An implantable cardiac pump acting as an assist device provided includes an attachment system and locating features that enable a minimally invasive procedure to implant and deploy one or more aortic blood pumps in a patient. The insertable cardiac pump is replaceable without resort to a conventional open surgical procedure. Monitoring of cardiac pump operation allows for replacement in advane of chamber failure. The dynamics of blood-contacting interface of the cardiac assist device mimic the dynamics of the blood-contacting interface of a naturally occurring left ventricle, thereby minimizing flow-related device-associated pathologic disturbances of intravascular clotting mechanisms. A process of operating a cardiac assist device includes cyclically inflating and deflating one or more inflatable cardiac pumping chambers with timing and parameters as to pressure, deflection, and speed of inflation to in crease patient cardiac output. | 2018-07-26 |
20180207336 | Device And A Method For Augmenting Heart Function - A device, a kit and a method are presented for permanently augmenting the pump function of the left heart. The basis for the presented innovation is an augmentation of the physiologically up and down movement of the mitral valve during each heart cycle. By means of catheter technique, minimal surgery, or open heart surgery implants are inserted into the left ventricle, the mitral valve annulus, the left atrium and adjacent tissue in order to augment the natural up and down movement of the mitral valve and thereby increasing the left ventricular diastolic filling and the piston effect of the closed mitral valve when moving towards the apex of said heart in systole and/or away from said apex in diastole. | 2018-07-26 |
20180207337 | COUNTERPULSATION DEVICE DRIVER APPARATUS, METHOD AND SYSTEM - A method of operating a counterpulsation device (CPD) in a human or animal subject is disclosed, the method including: receiving a heart beat signal indicative of the heart beat of the subject; providing counterpulsation therapy by controlling the pressure supplied to a CPD drive line in pneumatic communication with the CPD to cause the CPD to alternately fill with blood and eject blood with a timing that is determined at least in part based on the heart beat signal; while providing counterpulsation therapy, receiving a CPD drive line pressure signal indicative of the pressure in the CPD drive line; and adjusting the pressure supplied to the drive line based at least in part on the drive line pressure signal. | 2018-07-26 |
20180207338 | POWER SCALING - Disclosed are systems and methods for measuring and calculating parameters to control and monitor a power transfer in an implanted medical device, including operating the device in a plurality of scalable power modes and/or coupling modes. The system may shift between or among power and/or coupling modes based on input such as data received over system communication lines, programmable timers, or electrical loading information. The system may also shift between or among power and/or coupling modes based on calculated amounts of coupling, levels of detected heat flux, and/or amounts of estimated temperature changes. | 2018-07-26 |
20180207339 | DIALYSIS DEVICE - A dialysis device comprising a prescriber interface and a programming means configured to allow, via the prescriber interface, input of a set of therapeutic objectives and a treatment plan and a re-evaluation means configured to, as a function of the therapeutic objectives and the treatment plan, suggest at least one treatment option comprising a set of settings of a treatment session to achieve said set of therapeutic objectives. | 2018-07-26 |
20180207340 | ENHANCED BACKFLOW PREVENTION IN A HEMODIALYSIS DEVICE - A hemodialysis system according to an embodiment of the present invention includes a hydrochamber, and a water circuit for water to flow from an external water source into the hydrochamber via a water inlet valve. The hemodialysis system further includes a spent dialysate circuit for a disinfecting agent to flow to the hydrochamber via a recirculation valve during a disinfectant operation, and a drain valve disposed in the spent dialysate circuit. During the disinfectant operation, the hemodialysis system is adapted to replace a volume of the disinfecting agent exiting the spent dialysate circuit via the drain valve with an equal volume of water via the water inlet valve. The recirculation valve is directly connected to the hydrochamber such that in response to a pressure drop at the external water source, the disinfecting agent is prevented from backflowing through the water inlet valve. | 2018-07-26 |
20180207341 | MEDICAL APPARATUS FOR EXTRACORPOREAL TREATMENT OF FLUID AND A PROCESS OF CALCULATING SET FLOW RATES IN A MEDICAL APPARATUS FOR DELIVERY OR COLLECTION OF FLUIDS - An apparatus for extracorporeal treatment of fluid and a process of setting up a medical apparatus for the delivery or collection of fluids are disclosed. According to the apparatus and the process, a control unit ( | 2018-07-26 |
20180207342 | Water Treatment Systems, Devices, and Methods for Fluid Preparation - A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water. | 2018-07-26 |
20180207343 | BLOOD TREATMENT DEVICE - The present invention relates to a blood treatment device having a heat exchanger which has a first space and a second space, wherein the first space is flowed through by a first fluid and the second space is flowed through by a second fluid, and wherein the heat exchanger has a membrane which separates the first space from the second space, wherein the membrane forms a component of a capacitor which has two capacitor plates between which the membrane is located, and wherein monitoring means are provided which are connected to the capacitor and which are configured such that they detect an electrical property of the capacitor for the purpose of detecting a leak from the first space to the second space. | 2018-07-26 |
20180207344 | ARTIFICIAL LUNG - An artificial lung | 2018-07-26 |
20180207345 | Portable Ultrafiltration Unit And Device For Supplying The Ultrafiltration Unit With Dialysis Fluid - The invention relates to a portable ultrafiltration unit A which comprises a blood pump | 2018-07-26 |
20180207346 | CONTACTLESS ACTUATION FOR VALVE IMPLANT - An example magnetically activated implantable valve according to the present disclosure includes an implantable valve, the implantable valve including a first set of passive magnets, and an actuator configured to actuate the implantable valve. The actuator includes a second set of passive magnets corresponding to the first set of passive magnets. The first set of passive magnets is configured to interact with the second set of passive magnets to actuate the valve. Another example magnetically activated implantable valve and an implantable valve for controlling flow of an active fluid are also disclosed. | 2018-07-26 |
20180207347 | HEMODIALYSIS CATHETER WITH CORRUGATED TIPS - Hemodialysis catheter with corrugated tips. Includes elongated body having first and second distal end regions terminating in tips opened to lumens extending continuously along both elongated body and distal end regions. Each tip includes a tip edge extending from tip tubular wall and surrounding tip opening. Each tip tubular wall has a corrugated configuration with at least two grooves, including outer and inner grooves, merging into the tip edge. Grooves may have same or different lengths, widths, or/and spatial configurations. Distal end regions may be elastic and configured to have non-stressed form when divergent, via diverging angles, from elongated body longitudinal axis, and may be rotationally symmetric relative to the axis. In some embodiments, tip inner wall and hollow outer surfaces merge into a corrugated form having alternating grooves and ridges along distal ends of the tip, that enable the catheter to facilitate active lateral or frontal fluid traversability therethrough. | 2018-07-26 |
20180207348 | Control System - A cardioplegic agent delivery system comprises a supply reservoir ( | 2018-07-26 |
20180207349 | CELL WASHING USING ACOUSTIC WAVES - Disclosed is a device for separating a cellular component from a multicomponent fluid. The device can comprise a body, a first acoustic wave generator, and a second acoustic wave propagating component. The body can define a channel having a first surface and a second surface opposite the first surface. The channel can extend along a longitudinal axis from a first end to a second end. The first acoustic wave generator can be coupled to the first surface. The first acoustic wave generator can be configured to generate an acoustic wave having a wavelength. The second acoustic wave propagating component can be coupled to the second surface. The second surface can be spaced an integer fractional multiple of the wavelength from the first surface and each integer factional multiple equals a number of pressure nodes within the channel. | 2018-07-26 |
20180207350 | MICROPOROUS ZIRCONIUM SILICATE AND ITS METHOD OF PRODUCTION - The present invention relates to novel microporous zirconium silicate compositions having a desired particle size distribution and methods of making those compositions. These compositions have an ideal particle size distribution for use ex vivo, for example in a dialysis exchange cartridge, yet retain many of the desirable properties of prior improved absorbers including high cation exchange capacity. Further, the new zirconium silicate molecular sieve absorbers can be manufactured using a technique that achieves the desired particle size distribution while eliminating the screening step that was previously necessary. | 2018-07-26 |
20180207351 | Rectal Catheter Plastic Component for a Rectal Catheter Assembly, and Method for Producing a Rectal Catheter Plastic Component - A rectal catheter plastic component is a constituent part of a rectal catheter assembly. The one piece plastic component has a cylindrical main body with an outer jacket wall. A connector component end serves for the attachment of a peripheral hose. A free component end serves for rectal insertion. At least one media lumen, extending along the main body, is arranged between at least one media connector port and at least one media opening. The media connector port is located at the connector component end, and the media opening is configured in the free component end. A further balloon-filling lumen, extending along the main body, extends between a filling connector port and a balloon-filling opening. The filling connector port is located at the connector component end, and the balloon-filling opening is configured in a balloon attachment region of the plastic component for the attachment of a balloon cuff. | 2018-07-26 |
20180207352 | FLUID CONTROL APPARATUS - A fluid control apparatus comprises a housing; an inlet and an outlet coupled to the housing. A first flow path and a second flow path each having a front end connected to the inlet and a back end connected to the outlet to establish fluid communication between the inlet and the outlet through the first flow path and the second flow path. A flow controller is coupled to the second flow path, and a reservoir is in fluid communication with the second flow path via the flow controller. The flow controller is operable to fill fluid from the inlet to the reservoir, and to supply fluid from the reservoir to the outlet to provide a dose of supplementary medication to a patient. The apparatus may include a flow selector coupled to the first flow path to vary the flow rate of the fluid passing through the first flow path. | 2018-07-26 |
20180207353 | Portable Canister Holder with a Collapsible Body - A portable canister holder is disclosed. The portable canister system comprises a collapsible substantially cylindrical, non-rigid body assembly comprising a plurality of vertical support rods configured to support a plurality of horizontal support restraints. The vertical support rods pivot along with the horizontal supporting restraints, thereby collapsing the body assembly. The lowest horizontal support restraint further comprises a stopper to prevent the canister from being disconnected from the body assembly when in use. The portable canister holder further comprises an articulating joint member having a first end configured to attach to the body assembly and a second end configured to attach to a clamping device. The portable canister holder comprises an IV holder configured to attach to the body assembly, the IV holder having a plurality of rods configured to support an IV bag. The portable canister holder comprises a second IV holder configured to attach to the clamping device. | 2018-07-26 |
20180207355 | CANNULAS FOR DRUG DELIVERY DEVICES - Embodiments relate to a cannula that is provided for delivering a substance, such as a medicine (e.g., insulin) to a patient, where the cannula has reduced likelihood of kinking or occlusions when implanted in a patient. The cannula may have a reduced number of stress concentrations along its length, an angled tip and/or a curve in its length. The cannula may include other designs to reduce kinking, such as internal ribbing and/or a slit along its wall. | 2018-07-26 |
20180207356 | CONTINUOUS SUBCUTANEOUS INSULIN INFUSION CATHETER - A continuous subcutaneous infusion catheter includes an elongate flexible cannula and a plurality of holes through the cannula wall that are positioned both along the axial length of the cannula and radially around the cannula. The proximal end of the cannula is configured to be attached to a pump, and the distal end of the flexible cannula is atraumatic. The catheter can be used to deliver insulin to a patient. | 2018-07-26 |
20180207357 | Medical Drug Delivery Systems with Mixing Chamber - A drug delivery system provides for controlled mixing of drugs, using at least one mixing chamber. Flow controllers guide drugs into single or multiple catheters, enabling a single lumen catheter to dispense multiple drugs, diluting a concentrated drug to provide varying drug concentration. A buffer fluid can deliver precise drug amounts or can separate drugs within a catheter. A patient's bodily fluid can serve as a diluent or buffer fluid. A drug testing/filler apparatus may be used to facilitate filling of multiple reservoirs. Bolus or continuous delivery of drug to selected distal locations can occur at independent rates. New catheter systems, hub assemblies, and uses therefore are also described. New methods for promotion of healthy pregnancy and treatment of a developing fetus are disclosed. | 2018-07-26 |
20180207358 | LIQUID MEDICINE ADMINISTRATION APPARATUS AND LIQUID MEDICINE ADMINISTRATION UNIT - A liquid medicine administration apparatus includes: a drive section; an operation section configured to operate a pusher member that is slidably located in a liquid medicine container; a transmission mechanism configured to transmit a driving force of the drive section to the operation section; an occlusion detection mechanism located in the transmission mechanism and configured to detect occlusion of a passage of liquid medicine administered from the liquid medicine container; a rotation detector configured to detect rotation of the drive section; and a notification section configured to notify a user when the rotation detector detects stoppage of rotation of the drive section. | 2018-07-26 |
20180207359 | MEDICAL FLUID THERAPY SYSTEM HAVING MULTI-STATE ALARM FEATURE - A medical fluid therapy system includes a medical fluid pumping apparatus; a first medical fluid container holding a first medical fluid and including a first line extending to the pumping apparatus; a second medical fluid container holding a second medical fluid and including a second line extending to the pumping apparatus; and an alarm feature provided with the pumping apparatus and including a first alarm signal associated with a first low level event of the first or second fluid, a second alarm signal associated with a second low level event of the first or second fluid, and a snooze element configured to deactivate the first alarm signal after the first low level event has occurred and to enable the second alarm level to be activated upon occurrence of the second low level event. | 2018-07-26 |
20180207360 | MAGNETIC PRESSURE SENSING SYSTEM FOR AN INFUSION PUMP - An infusion pump having one or more magnetic pressure sensors for detecting tubing occlusions is provided with at least one corresponding secondary Hall effect sensor arranged to detect an ambient magnetic field influencing pressure measurements so that corrective action may be taken to mitigate the effects of the ambient magnetic field. | 2018-07-26 |
20180207361 | ACTUATING DEVICE FOR ADMINISTERING A BOLUS - A device for administering a bolus, includes an actuating element to actuate a closing mechanism which opens and closes a hose segment. The hose segment can be connected to a fluid source and to a patient. The device also includes a movable element, a blocking element which locks the movable element in an upper position and which can be released by the actuating element, an elastic element which pushes the actuating element and movable element apart, a first actuation blocking element which locks the actuating element in a lower position and can be released by the movable element, and a bolus reservoir for holding a bolus quantity of fluid. The volume of the bolus reservoir can be reduced by displacing the movable element. A second actuation blocking element locks the actuating element in the upper position can be released by the movable element. | 2018-07-26 |
20180207362 | LIQUID PARAMETER DETECTING METHOD AND SYSTEM - The present disclosure provides a liquid detection system for detecting a liquid level position of a liquid in a hanging bottle. The system includes a hanging bottle casing unit for determining the overall gravity of the hanging bottle, a hanging bottle cap unit for determining the liquid density in the hanging bottle, and a transmission unit for transmitting the overall gravity and liquid density of the hanging bottle to a server, and the server. The server is configured to determine the liquid gravity in the hanging bottle, calculate the liquid volume in the hanging bottle based on the liquid gravity and the liquid density, and determine a liquid level position based on the liquid volume. | 2018-07-26 |
20180207363 | AUTO-INJECTOR - An autoinjector having a body ( | 2018-07-26 |
20180207364 | Dose Setting Mechanism for Priming a Drug Delivery Device - A method and system for providing a drug delivery device. The drug delivery device comprises a dose setting mechanism comprising a spindle and a cartridge holder coupled to the dose setting mechanism. The cartridge holder comprising a cartridge having a movable bung at one end of the cartridge. The cartridge holder must be rotated before a dose may set with the dose setting mechanism. | 2018-07-26 |
20180207365 | HYPODERMIC SYRINGE WITH VIAL ATTACHMENTS - A medical syringe apparatus includes a syringe unit, a hypodermic needle attached to the syringe unit and at least one interfacing member for mating a labeled medication container to the syringe unit. A filling needle is attached to the syringe unit for drawing fluid from a container. A movable needle sheath protects the hypodermic needle when not in use and may be moved out of the way when administering an injection. The medication label is visible. The container remains mated to the syringe when the syringe is in use. Risk of mislabeling the syringe may therefore be substantially reduced or eliminated and patient safety may accordingly be improved. | 2018-07-26 |
20180207366 | DOSE CONTROL SYSTEM FOR INJECTABLE-DRUG DELIVERY DEVICES AND ASSOCIATED METHODS OF USE - The present invention relates to a dose control system adapted for an injectable drug delivery device, the drug delivery device comprising a substantially elongate drug delivery body, at least one injectable drug held by the body, the body having a distal and proximal extremity, wherein the dose control system comprises three-dimensional magnetic field producing means for producing a magnetic field along three axes (x,y,z); magnetic field detection means configured to detect changes in at least the magnetic field produced by the three-dimensional magnetic field producing means; displacement detection means configured to measure a relative displacement or relative movement of the drug delivery device, and an integrated control unit, wherein the integrated control unit is connected to the magnetic field detection means, and to the displacement detection means, for processing information received from both the magnetic field detection means and the displacement detection means; wherein the three-dimensional magnetic field producing means is configured to effect a rotating coaxial displacement around, and along, a longitudinal axis of the drug delivery system; the magnetic field detection means are located along said longitudinal axis; and the three-dimensional magnetic field producing means is located at, or near, a proximal extremity of the body of the drug delivery device. | 2018-07-26 |
20180207367 | CAP AND CAP REMOVAL DEVICE - A cap removal device for removing and retaining a plurality of caps from a drug delivery device includes a body having a plurality of recesses. Each of the plurality of recesses comprises a shape corresponding to a shape of one of the plurality of caps and each recess is provided with an engagement member adapted to engage a cap. Furthermore, a cap adapted to be mounted to a distal end of a drug delivery device includes a distal portion comprising a shape corresponding to a shape of a recess of the cap removal device. | 2018-07-26 |
20180207368 | DEVICES, SYSTEMS AND METHODS FOR CONTROLLING CONDITIONS AND DELIVERY OF SUBSTANCES - Embodiments of the present disclosure are directed to devices, systems, and methods for controlling environmental conditions for a volume of material. In some embodiments, a handheld, portable environmental control sleeve (ECS) is disclosed which is configured for controlling at least one environmental condition of a drug contained within a drug delivery or storage device (DDSD). The ECS includes an environmental control mechanism (ECM), thermal insulation material, at least one of a power source, a processor, at least one electrical contact, at least one indicator, at least one switch, at least one environmental condition sensor, a wireless transceiver, a phase change material and at least one heat dissipater. Upon the ECS receiving at least a portion of the DDSD, the at least one environmental condition of a drug contained within the DDSD is controlled by the ECM to be within a predetermined range. | 2018-07-26 |
20180207369 | MEDICAL FLUID INJECTION DEVICE WITH FILL INDICATOR - An injection device has a generally disc-shaped housing including an arcuate clear section and graduated markings in an arcuate arrangement on or adjacent to the clear section. An arcuately expandable member is contained within the housing and is configured to hold a volume of liquid. An indicator is connected to the expandable member and positioned within the housing. The indicator is configured to move along an arcuate path adjacent to the clear section such that alignment of the indicator with the graduated markings indicates a volume of liquid within the expandable member. | 2018-07-26 |
20180207370 | INHALER DEVICE FOR INHALABLE LIQUIDS - The present invention provides a new inhaler device for the storage and administration of inhalable liquids to a patient, such as halogenated volatile liquids, particularly methoxyflurane for use as an analgesic, the device having one or more advantages or improvements over known inhalers. | 2018-07-26 |
20180207371 | ATOMIZER, ATOMIZING ASSEMBLY AND INHALER - An atomizer for an inhaler includes a housing, a gasket, a liquid absorbing sheet, a wick, and an atomizing element. The housing includes a first housing and a second housing, the first housing and the second housing form a liquid reservoir therebetween for storing liquid. The gasket is sleeved on the first housing, the gasket defines a liquid conducting hole in communication with the liquid reservoir. The liquid absorbing sheet is sleeved on the first housing in contact with the gasket, the liquid absorbing sheet is configured to absorb the liquid in the liquid reservoir via the liquid conducting hole. The wick is in contact with the liquid absorbing sheet and configured to draw the liquid from the liquid absorbing sheet. The atomizing element is fixed to the wick and configured to atomize the liquid in the wick. | 2018-07-26 |
20180207372 | INSUFFLATION STABILIZATION SYSTEM - Pressure conditioning systems for supplying insufflation gas to an open-ended body conduit such as a rectal cavity during a transanal minimally invasive surgery (TAMIS) procedure can reduce billowing of walls of the body conduit. A pressure conditioning system can include a pressure storage component, an accumulator, and a flow restrictor. The pressure storage component can include a variable volume reservoir that is biased to a relatively low volume state. The flow restrictor can include insufflation tubing with a restrictor plate having a relatively low diameter orifice. The pressure storage component, accumulator, and flow restrictor can be fluidly connected in various orders in series or as side branches from a gas flow conduit. Despite a pulsed or otherwise discontinuous insufflation gas flow and leakage and absorption from the body conduit, the pressure conditioning system can maintain a constant pressure within the body conduit. | 2018-07-26 |
20180207373 | MEDICAL DEVICE NOTIFICATION SYSTEM - A system and method for communicating data from a medical device to a lighting device is provided. The system may include the medical device, the lighting device, and/or one or more interface devices. The medical device may be configured to transmit data to the lighting device, which for example, may include information relating to the medical device, dosage information, diagnostic data, medical device training feedback, health monitoring information, and/or air quality information. The lighting device may be configured to receive data from the medical device and control one or more lighting characteristics based on the received data. A characteristic of the light may include one or more of color, color temperature, intensity, flashing or steady-state, on or off, and/or the like. The system may provide for a home based adherence and/or compliance monitoring system, in which a patient's interaction with a medical device may be monitored and an alert/indication provided. | 2018-07-26 |
20180207374 | Dose Delivery Device for Inhalation with First and Second Portions to Open a Dose Chamber - A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. | 2018-07-26 |
20180207375 | PRESSURIZED METERED DOSE INHALERS AND METHOD OF MANUFACTURE - The invention relates to a method for the manufacture of a pressurized Metered Dose Inhaler (pMDI) and components for use in the method, in particular, a pMDI compatible tablet (i.e. one that is able to be dispersed or disintegrates within a liquid phase, such as a propellant, used in a pMDI formulation) which contains at least one active pharmaceutical ingredient (API) and, potentially, one or more excipients. | 2018-07-26 |
20180207376 | AEROSOL GENERATING SYSTEM WITH A RUPTURING SYSTEM FOR A CONTAINER - An aerosol-generating system is provided, including a first container including at least one aerosol-generating substrate; a rupturing system including a first tube and a second tube, the first and second tubes being arranged in operational engagement defining a volume, wherein the first and second tubes are movable relative to each other along a first motion path from a first position to a second position, such that the defined volume is larger in the first position than in the second position, wherein the first tube includes a first rupturing member disposed at least partially inside the first tube, such that in the first position, the first rupturing member is contained completely in the defined volume of the first and second tubes, and wherein in the second position, the first rupturing member at least partially protrudes from the defined volume to rupture the container including said substrate. | 2018-07-26 |
20180207377 | A RUPTURING SYSTEM FOR AN AEROSOL-GENERATING SYSTEM - A rupturing system for an aerosol-generating system is provided, the rupturing system including a first tube and a second tube being movable relative to each other along a first motion path from a first position to a second position, such that the defined volume is larger in the first position than in the second position; a rupturing member connected to one of the first tube and the second tube, the rupturing member being arranged such that in the first position the rupturing member is contained completely in the defined volume of the first tube and the second tube, and in the second position the rupturing member at least partially protrudes from the defined volume and is configured to rupture a container; and a first wrapper overlying at least a portion of the first tube and being attached to the first tube. | 2018-07-26 |
20180207378 | SYSTEMS AND METHODS FOR TRIGGERING AND CYCLING A VENTILATOR BASED ON RECONSTRUCTED PATIENT EFFORT SIGNAL - Various embodiments of the present disclosure provide systems, methods and devices for respiratory support. As one example, a method for respiratory support is described that includes providing a measured pressure, and calculating a net flow based on at least one measured inlet flow and measured outlet flow. A relationship between a first value related to the measured pressure, a second value related to the measured net flow and a third value related to patient effort is used to provide a prediction of patient effort. An interim value is updated based at least in part on the prediction of the patient effort, and used to help compute a patient effort. A ventilation cycle is initiated using the computed patient effort. | 2018-07-26 |
20180207379 | SYSTEMS AND METHODS FOR DETERMINING PATIENT EFFORT AND/OR RESPIRATORY PARAMETERS IN A VENTILATION SYSTEM - Various embodiments of the present disclosure provide systems, methods and devices for respiratory support. As one example, a method for respiratory support is described that includes measuring a pressure, providing a measured pressure, measuring an inlet flow and an outlet flow, and providing a measured net flow. A relationship between a first value related to the measured pressure, a second value related to the measured net flow and a third value related to patient effort is used to provide a prediction of patient effort. An interim value is updated based at least in part on the prediction of the patient effort. | 2018-07-26 |
20180207380 | TOUCH-SENSITIVE USER INTERFACE INTENDED FOR A TRACHEOBRONCHIAL-AIR STIMULATION DEVICE - Disclosed is a touch-sensitive user interface intended to interact with a tracheobronchial-air stimulation device including: —a touch-sensitive display screen for providing the user with information about the use of the tracheobronchial-air stimulation device, —a communication module for communicating data between the touch-sensitive user interface and the tracheobronchial-air stimulation device, —a memory in which biofeedback software and data, referred to as input data, may be saved, and —a data processing unit configured by the biofeedback software. | 2018-07-26 |
20180207381 | Tracheostomy tube with removable neck flange - A tracheal tube assembly includes an outer cannula configured to be positioned in a patient airway and an inner cannula configured to be disposed inside the outer cannula. The tracheal tube assembly includes a removable neck flange bracket with trach tie adapter points secured about the outer cannula, and a connector coupled to a proximal end of the outer cannula. The connector can include a swivel design feature and a flexible tubing connector may be formed with the connecter. The connector is constructed and arranged to provide a view of the inner cannula, and the inner cannula and the connector form a contiguous passageway for exchanging fluid with the patient airway in operation. | 2018-07-26 |
20180207382 | ADJUSTABLE TRACHEOSTOMA VALVE - An adjustable tracheostoma valve is disclosed. The adjustable tracheostoma valve includes a passageway for connecting the trachea with the surroundings. A valve disk is provided in the passageway. The disk is moveable to allow for inhalation and exhalation through the passageway and is configured to close in response to pressure to direct air to the patient's pharynx, esophagus, sinuses, and mouth for speech following surgical removal of the larynx. | 2018-07-26 |
20180207383 | ENDOTRACHEAL TUBE INSERTION DEVICE - An endotracheal tube insertion device includes an insertion member, a flexible optical assembly member movably mounted to the insertion member, an endotracheal tube, and an endotracheal tube attachment member attached to the insertion member and configured to receive and retain the endotracheal tube. | 2018-07-26 |