31st week of 2015 patent applcation highlights part 10 |
Patent application number | Title | Published |
20150209470 | Oxygenated Oil Ointment - An oxygenated oil ointment is made, for example, by stirring or agitating plant-based oil while injecting a gas into the plant-based oil, resulting in a coagulated ointment that is beneficial for topical application. In one example, the plant-based oil is olive oil and the gas includes ozone, which is known to kill pathogens. For some plant-based oils, the ozone increases amounts of peroxide in the plant-based oils. Once the olive oil coagulates with the ozone, the resulting ointment retains some of the ozone gas until the ointment is applied on the skin for treatment of, for example, cuts and sores. In some ointments, the pH of the plant-based oil is increased by adding one or more alkaline materials to the plant-based oil before coagulation occurs. This increase in alkalinity improves the ointment's ability to give off ozone and oxygen. | 2015-07-30 |
20150209471 | Metal Oxide Scaffolds - The present invention relates to a metal oxide scaffold comprising titanium oxide. The scaffolds of the invention are useful for implantation into a subject for tissue regeneration and for providing a framework for cell growth and stabilization to the regenerating tissue. The invention also relates to methods for producing such metal oxide scaffolds and their uses. | 2015-07-30 |
20150209472 | COLLAGEN PERMEATED MEDICAL IMPLANTS - The invention herein relates to the field of attaching and securing manmade material onto or into bone in correcting bone defects by implanting stress-bearing bone replacements. In particular, the invention relates to applying a coating of collagen securely onto the implant to ensure the collagen material will not be removed from the implant during installation, such as screwing the anchor into the bone. This addresses the removal of the coatings by the scraping action of the bone on the soft collagen. In the past, it has not been possible to provide adequate adhesive strength to the bone collagen/implant interface or the cohesive force of the collagen itself to prevent the removal of the coating by the abrasive action between bone and known implants. | 2015-07-30 |
20150209473 | METHODS OF MODIFYING MYOCARDIAL INFARCTION EXPANSION - A bioscaffolding can be formed within a post-myocardial infarct region sufficient to cause attenuation of a rate of myocardial infarct expansion. A bioscaffolding may further be formed in the post-myocardial infarct region to cause an increase in posterior left ventricular wall thickness. The gel or bioscaffolding can be formed from a mixture of gel components of different gelation systems. For example, a bioscaffolding can be formed by mixing at least two different components of at least two different two-component gelation systems to form a first mixture and by mixing at least two different components (other than the components that make up the first mixture) of the at least two different two-component gelation systems to form a second mixture. | 2015-07-30 |
20150209474 | METHOD FOR PRODUCING AN ALGINATE COATED TITANIUM DIOXIDE SCAFFOLD - The present document is directed to medical prosthetic devices used for implantation to replace and/or restore lost functions in a body. The document discloses a method for producing an alginate coated titanium dioxide scaffold wherein the alginate coating optionally comprises a biologically active substance. | 2015-07-30 |
20150209475 | PLACENTAL TISSUE GRAFTS - A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion. | 2015-07-30 |
20150209476 | Method For Manufacturing Allogeneic Soft-Tissue Transplant Having Autologous Stem Cell Transplanted Therein - Provided is a method of manufacturing an allogeneic soft-tissue transplant having autologous stem cells transplanted therein using an allogeneic soft-tissue support that is obtained from an allogeneic organism. In this regard, an allogeneic soft-tissue transplant that can replace a damaged soft-tissue of a human body is manufactured. | 2015-07-30 |
20150209477 | COMPOSITIONS FOR BIOMEDICAL APPLICATIONS - The invention relates to composite materials that contain a polymer matrix and aggregates, and in some embodiments, methods of making, and methods of using these materials. Preferably, the aggregates are calcium phosphate aggregates. Preferably, the material is resistant to fracture. In further embodiments, the materials are used in surgical procedures of bone replacement. In further embodiments, the materials contain polyhedral silsesquioxanes and/or biodegradable segments. In further embodiments, the polymer matrix comprises biomolecules. | 2015-07-30 |
20150209478 | Articles for Tissue Regeneration with Biodegradable Polymer - The invention is to articles made from extracellular matrix sheets that encase biodegradable polymeric material. Methods of healing wounds or regenerating tissue at sites of defect by placing said articles in mammals are claimed. The biodegradable polymer can change quality upon contact with a physiological parameter such as temperature or pH that causes, for example, a liquid polymer to gel or harden. The degradation of the polymer can be controlled to suit a tissue regeneration or wound healing time course. Additional components such as proteins, cells and drugs can be added to the biopolymer composition. | 2015-07-30 |
20150209479 | METHODS AND DEVICES FOR CELLULAR TRANSPLANTATION - Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold. | 2015-07-30 |
20150209480 | OSSEO-INDUCTIVE METAL IMPLANTS FOR A LIVING BODY AND THE PRODUCING METHOD THEREOF - Discussed is a an Osseo-inductive metal implant for a living body having a layer of metal oxide and a layer of bio-active material formed in this order on the surface of the metal implant. | 2015-07-30 |
20150209481 | Antiadhesive Material - An antiadhesive material is provided and contains a poly-γ-glutamic acid having a weight-average molecular weight of 600,000 to 13,000,000, or a kinematic viscosity at 37° C. of 2 cSt to 15 cSt when dissolved in distilled water at a concentration of 0.05% by mass and/or a salt thereof, as an effective ingredient. The antiadhesive material may have any form such as powder or gel form, and therefore, for example, is easy to handle even in relatively localized surgery such as endoscopic surgery and can more reliably prevent adhesion. | 2015-07-30 |
20150209482 | CROSS-LINKED FATTY ACID-BASED BIOMATERIALS - Fatty acid-based, pre-cure-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided. | 2015-07-30 |
20150209483 | BIOABSORBABLE MEDICAL DEVICES AND METHODS OF USE THEREOF - One aspect provides implantable medical devices including a bioabsorbable structure having a surface and having a coating layer on at least a portion of the surface. In certain embodiments, the coating layer includes a releasable bioactive and provides for a controlled absorption of the bioabsorbable structure upon implantation in a human or veterinary patient. Another aspect provides methods treating a disease including implanting such a device in a vessel of a human or veterinary patient. | 2015-07-30 |
20150209484 | BONE CONNECTION MATERIAL - The present invention provides a bone connection material that includes an internal layer. The internal layer is formed by braiding a plurality of filaments. The internal layer that is formed by braiding filaments is resistant to lateral shearing forces and may provide flexibility so as to achieve wide applications. Further, the present invention overcomes the drawback of the conventionally used metallic materials that are rigid and inelastic and also overcomes the problem of polylactic acid material of being brittle. Thus, the bone formed according to the present invention is close to a natural bone and is more suitable for uses in portions where frequent movements are made and scaffolds of stem cells. | 2015-07-30 |
20150209485 | INTERVENTIONAL MEDICAL DEVICE AND MANUFACTURING METHOD THEREOF - An interventional medical device and manufacturing method thereof. The interventional medical device comprises: a stent body ( | 2015-07-30 |
20150209486 | Methacrylate Copolymers For Medical Devices - A polymer of hydrophobic monomers and hydrophilic monomers is provided. It is also provided a polymer blend that contains the polymer and another biocompatible polymer. The polymer or polymer blend and optionally a biobeneficial material and/or a bioactive agent can form a coating on an implantable device such as a drug delivery stent. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof. | 2015-07-30 |
20150209487 | DRUG DELIVERY DEVICES AND METHODS OF MAKING AND USING SAME - The disclosure provides drug delivery devices and methods of making and using the drug delivery devices. The devices include single and multi-layer polymer films made by a breath figure technique having therapeutic agents associated therewith. For example, the devices may be a dual layer polymer film wherein the first layer includes a therapeutic agent incorporated into it by spin coating the first agent with a polymer solution and the second agent is incorporated into the second layer by loading the agent into pores of the second layer after it is spin coated onto the first layer. In some cases one layer provides a burst release and the second layer provides a slow release drug delivery profile. The devices may take on the form of a surgical mesh with a slow release therapeutic drug. | 2015-07-30 |
20150209488 | POLYMER-BASED SURGICALLY IMPLATABLE HALOPERIDOL DELIVERY SYSTEMS AND METHODS FOR THEIR PRODUCTION AND USE - Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia. | 2015-07-30 |
20150209489 | DRUG RELEASING COATINGS FOR MEDICAL DEVICES - The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent, an antioxidant, and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In some embodiments, the additive is a liquid. In other embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has one or more hydroxyl, amino, carbonyl, carboxyl, acid, amide or ester groups. | 2015-07-30 |
20150209490 | SURGICAL CASSETTE APPARATUS - A surgical cassette arrangement is provided. The arrangement includes a flow selector valve configured to operate with a handpiece to selectively irrigate and aspirate fluid with respect to an ocular region. The flow selector valve includes at least three ports, with one port fluidly connectable to the handpiece. The arrangement further includes a reservoir fluidly connected to a second port of the flow selector valve via a first flow segment and configured to receive fluid from the flow selector valve, and a collector fluidly connected to a third port of the flow selector valve via a second flow segment and configured to receive fluid from the flow selector valve and from the reservoir. The flow selector valve selectively controls irrigation and aspiration flow to the handpiece and ocular region. | 2015-07-30 |
20150209491 | SYSTEM AND METHOD FOR TISSUE SPECIMEN COLLECTION - A system and method for retaining a tissue specimen obtained via a collection tube is provided. Embodiments provide a system including a collection device removably and serially disposed between a collection tube and a suction tube so as to allow fluid communication therebetween via the collection device. The collection device includes a screen for retaining a tissue specimen drawn into the collection device by and towards the suction tube while allowing any fluid accompanying the tissue to be drawn through the collection device and into the suction tube. The system also includes one or more end caps for sealing the collection device such that the collection device may store and/or transport the retained tissue specimen in a preservation fluid. A system for identifying and organizing collection devices retaining tissue specimens from various anatomical regions is also provided. | 2015-07-30 |
20150209492 | APPARATUS FOR ASPIRATING, IRRIGATING AND CLEANSING WOUNDS - An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g. microfiltration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing and a method of treatment using the apparatus. | 2015-07-30 |
20150209493 | NEGATIVE PRESSURE DRESSING AND METHOD OF USING SAME - Disclosed herein are apparatuses and methods for treating a wound by applying reduced or negative pressure to the wound. The apparatus can include a wound cover, a fluid collection container, a vacuum pump, an inflation pump, and one or more conduits. The wound cover can be configured to move between at least a relatively rigid, generally raised position and a relatively flexible, generally collapsed position according to a predetermined program or in response to input from a user or one or more sensors. In some embodiments, the wound cover can be configured to move between at least the relatively rigid, generally raised position and the relatively flexible, generally collapsed position by adjusting the air pressure in one or more channels in the wound cover or by adjusting the length of piezoelectric or other length changing material supported by the wound cover. | 2015-07-30 |
20150209494 | MOBILE SYSTEM FOR SEPARATING DONOR BLOOD BY MEANS OF GRAVITATIONAL FORCE - A mobile system for separating donor blood by gravitational force into erythrocyte concentrate and plasma. The system includes a first bag serving as a reservoir for the blood to be separated and at least a second and third bag for respectively receiving the erythrocyte concentrate and plasma, and also multiple tubes for connecting the flexible bags to a separator module having a separating membrane in the form of a bundle of hollow fibers. This system is divided into at least one first and one second sterilely packaged, individual subsystem. The first subsystem includes the individual bags and associated connection tubes and the second subsystem includes the separator module, and male/female connectors. | 2015-07-30 |
20150209495 | BLOOD BAG SYSTEM AND CASSETTE - A blood bag system includes a BC pooling bag for centrifugation of a buffy coat, a filter for removing white blood cells from a supernatant liquid transferred from the BC pooling bag, a platelet preserving bag for reserving the supernatant liquid that has passed through the filter, a first tube connecting the BC pooling bag and an inlet of the filter, a second tube connecting the platelet preserving bag and an outlet of the filter, and a cassette to be fixed in the centrifugation and separation apparatus. The first tube and the second tube are disposed within the cassette. The cassette includes a first clamp section for closing and opening the first tube, and a second clamp section for closing and opening the second tube. | 2015-07-30 |
20150209496 | BLOOD BAG SYSTEM AND CASSETTE - A blood bag system includes a BC pooling bag for centrifugation of a buffy coat, a filter for removing white blood cells from a supernatant liquid transferred from the BC pooling bag, a platelet preserving bag for reserving the supernatant liquid that has passed through the filter, a first tube connecting the BC pooling bag and an inlet of the filter, a second tube connecting the platelet preserving bag and an outlet of the filter, and a cassette to be fixed in the centrifugation and separation apparatus. The first tube and the second tube are disposed within the cassette. The cassette includes a first clamp section for closing and opening the first tube, and a second clamp section for closing and opening the second tube. | 2015-07-30 |
20150209497 | ACTUATOR CONTROL IN A BREAST PUMP SYSTEM - The present application relates to a breast pump system comprising a pump unit, an actuator for driving the pump unit, and a power supply for supplying electrical power to the actuator, and also to a method for use in such as system. An actuator speed regulating module is provided to drive the actuator at a first speed when the pump unit is turned on, and to continue to drive the actuator at a second speed higher than the first speed after a load on the actuator reaches a predetermined level. | 2015-07-30 |
20150209498 | BLOOD PUMP SYSTEMS AND METHODS - The present invention relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min. The rotary blood pump is part of a blood pump system that includes blood conduit(s), a control system with optional sensors, and a power source. Embodiments of the present invention may include elements such as wear resistant bearing materials, a rotor back plate for magnetic attraction of the rotor to reduce bearing pivot bearing forces and wear, a rotor size and shape and a bearing gap that combine to create a hydrodynamic bearing effect and reduce bearing pivot bearing forces and wear, improved intravascular conduits with increased resistance to thrombosis, conduit insertion site cuffs to resist infection, and conduit side ports amenable to the easy insertion of guidewire and catheter-based medical devices. | 2015-07-30 |
20150209499 | DIALYSIS SYSTEM WITH CASSETTE BASED BALANCE CHAMBERS AND VOLUMETRIC PUMPS - A dialysis system includes a fresh dialysis fluid pump, a used dialysis fluid pump, a fresh fluid flow path, a used fluid flow path, and a dialysis fluid cassette carrying a balance chamber, the balance chamber including a first rigid portion, a second rigid portion, and a flexible sheet located between the first and second rigid portions, the flexible sheet dividing the balance chamber into (i) a fresh dialysis fluid compartment connected fluidly to the fresh dialysis fluid pump via the fresh fluid flow path, wherein fresh dialysis fluid contacts the first rigid portion and a first side of the flexible sheet, and (ii) a used dialysis fluid compartment connected fluidly to the used dialysis fluid pump via the used fluid flow path, wherein used dialysis fluid contacts the second rigid portion and a second side of the flexible sheet. | 2015-07-30 |
20150209500 | HEMODIALYSIS AND PERITONEAL DIALYSIS SYSTEMS HAVING ELECTRODIALYSIS AND ELECTRODEIONIZATION CAPABILITIES - Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodialysis and electrodeionization capabilities are provided. In an embodiment, the dialysis system includes a carbon source, a urease source, an ED/EDI unit. The carbon source, urease source, and/or the ED/EDI unit can be in the form of removable cartridges. | 2015-07-30 |
20150209501 | SAFETY FEATURES FOR MEDICAL DEVICES REQUIRING ASSISTANCE AND SUPERVISION - An automatic locking system for a medical treatment device helps to ensure that an assistant is present during treatment of a patient. Among the features disclosed biometric authentication to verify that a trained assistant is present, a presence detector to ensure the assistant is continuously present during treatment, and warning and recovery processes that allow intermittent lapses in the continuous presence of the assistant. | 2015-07-30 |
20150209502 | TRIPLE SYRINGE AND METHODS OF MAKING PLATELET-ENRICHED PLASMA AND USE THEREOF - A triple syringe system that allows for either a larger volume of ACP, or a larger combined output of PRP (platelet rich plasma) and PPP (platelet poor plasma). The different outputs are based upon different centrifuge spin regimes. The system of the present invention produces up to 15 mL of ACP, or 3 mL of PRP plus 25 mL of PPP. The system of the present invention solves the problem of a larger volume of ACP and with a higher cellular concentration. The multi-syringe system allows for the connection of two or more additional syringes. The fractions may be extracted with the multi-syringe system of the present invention at different sequential times, or at the same time. | 2015-07-30 |
20150209503 | Syringe Packaging System Including Oxygen Absorber - A syringe packaging system that includes a packaging member defining a first compartment, a second compartment, and a third compartment that are in gaseous communication theretogether is disclosed. The first compartment is structured to receive a syringe barrel therein, the second compartment is structured to receive a plunger rod therein, and the third compartment is structured to receive an oxygen absorber therein. With the packaging member enclosing the syringe barrel, the plunger rod, and the oxygen absorber, the oxygen absorber is adapted to draw oxygen from within the syringe barrel and to absorb oxygen contained within at least one of the first compartment, the second compartment, and the third compartment of the packaging member. The syringe packaging system of the present disclosure also allows for reduced storage space of a syringe assembly. | 2015-07-30 |
20150209504 | MEDICAL UNIT FOR INJECTING A PATIENT WITH RUBIDIUM 82 - A medical unit for injecting a patient with an elution solution containing rubidium 82, includes, elements for receiving a strontium/rubidium generator capable of producing an elution solution that contains the rubidium 82 and that is capable of being contaminated by strontium 82 and/or strontium 85. This medical unit includes: —own elements thereof for acquiring a value related to at least one safety parameter that is associated with a maximum threshold value corresponding to a potentially excessive contamination of the elution solution with strontium 82 and/or strontium 85, and —control elements including safety elements that are controlled in an active configuration when the acquired value reaches the maximum threshold value of the safety parameter, the safety elements being capable, in the active configuration, of operating the infusion elements to the stop position in order to prevent an injection of the elution solution into the patient. | 2015-07-30 |
20150209505 | CONTROLLED DELIVERY DRIVE MECHANISMS FOR DRUG DELIVERY PUMPS - A controlled delivery drive mechanism includes a drive housing, a piston, and a biasing member initially retained in an energized state and is configured to bear upon an interface surface of the piston. The piston is configured to translate a plunger seal and a barrel. A tether is connected between the piston and the winch drum to restrain the free expansion of the biasing member and the free axial translation of the piston upon which the biasing member bears upon. The drive mechanism may further include a gear assembly having a motor configured to drive the gear assembly to release the tether from the winch drum. The metering of the tether by the motor controls the rate or profile of drug delivery to a user. A drug delivery pump includes such a controlled delivery drive mechanism. A control system may be utilized to control the desired drug delivery rate/profile. | 2015-07-30 |
20150209506 | ELASTIC BAND POWERED FLUID DELIVERY APPARATUS - This invention relates to a fluid delivery apparatus, system and method, in particular the use of elastic bands to generate the force required to push fluid out from a container. The fluid that is delivered from the container maybe prefilled and stored prior to its actuation by the elastic band driver or it could be filled just before use. In one embodiment disclosed, a prefilled option would require the user to attach an appropriate extension tubing that acts as a flow control tube to the fluid container which in one embodiment is tubular shaped. In the application where the device is filled just before use, the fluid container that would be engaged with the actuating housing is presented with a fixed rate flow tube. The selection of a particular device configuration replaces the need for programming a flow rate into an electronic syringe pump. | 2015-07-30 |
20150209507 | SYRINGE - A syringe for a power injector includes a barrel having a distal end and a proximal end. The barrel defines an interior volume therebetween the distal and proximal ends. A circumferential flange extends about the proximal end. A delivery tip extends from the distal end. The barrel includes a thick wall section adjacent the distal end and a thin wall section adjacent the proximate end. | 2015-07-30 |
20150209508 | SELF-CONTAINED SPRING INSERTER FOR DRUG DELIVERY INFUSION SET - An infusion set includes a base ( | 2015-07-30 |
20150209509 | METHODS AND DEVICES FOR INSERTING A NEEDLE - An apparatus provides targeted placement of openings for infusing fluids into a body. The apparatus provides a driving force to a penetrating medical device, such as a needle, when the apparatus tip encounters material of high resistance. When the apparatus tip encounters a low resistance material, no further driving force is applied to the apparatus due to contraction of an element made of interlaced flexible elements. A multi-opening needle is provided in some embodiments wherein placement of one of the openings in a target region with a relatively lower external pressure allows pressurized fluid to exit the needle while openings remaining in higher pressure, non-target regions do not release substantial amounts of the fluid. | 2015-07-30 |
20150209510 | System and Method for Assuring Patient Medication and Fluid Delivery at the Clinical Point of Use - A system for confirmation of fluid delivery to a patient at the clinical point of use is provided. The system includes a wearable electronic device. The wearable electronic device has a housing; at least one imaging sensor associated with the housing; a data transmission interface; a data reporting accessory for providing data to the user; a microprocessor for managing the at least one imaging sensor, the data transmission interface, and the data reporting accessory; and a program for acquiring and processing images from the at least one imaging sensor. The system further includes a fluid delivery apparatus; and one or more identification tags attached to or integrally formed with the fluid delivery apparatus. The program processes an image captured by the at least one imaging sensor to identify the one or more identification tags and acquires fluid delivery apparatus information from the one or more identification tags. | 2015-07-30 |
20150209511 | FLUID TRANSPORT APPARATUS, AND METHOD OF CONTROLLING FLUID TRANSPORT APPARATUS - A fluid transport apparatus includes: a pump configured to change a volumetric capacity of a container in which a fluid is stored to cause the fluid to flow; a flow channel connected to a downstream side of the pump in a direction of flow of the fluid and configured to allow the fluid to flow therein; a pressure transmitting plate arranged so as to be capable of coming into abutment with a first member which constitutes at least part of the flow channel; and a pressure sensor configured to detect a force for displacing the pressure transmitting plate. The fluid transport apparatus is capable of detecting an abnormality in transportation of the fluid. | 2015-07-30 |
20150209512 | Prefilled Syringes and Kits Thereof - The present disclosure relates, in part, to a kit including at least two prefilled syringes. The first prefilled syringe includes a dose of a hazardous agent in a first volume of a pharmaceutical composition comprising a pharmaceutically acceptable solvent. | 2015-07-30 |
20150209513 | MONITORING CONDITIONS OF AN IMPLANTABLE MEDICAL FLUID DELIVERY DEVICE - A programmer device includes an interface that communicates with an implantable fluid delivery device and a user interface that allows a user to troubleshoot a catheter connected to the fluid delivery device by measuring a pressure associated with the catheter. A processor may compare the measured pressure waveform to a previously-acquired waveform or the user interface may display the measured pressure waveform for the user to compare the displayed pressure waveform to a previously-acquired baseline waveform. The comparison between the two waveforms may be based on the pressure decay time. A historical log of measured pressure decays associated with the catheter may be maintained by the programmer device or the implantable fluid delivery device and displayed for the user to determine whether the performance of the catheter is deteriorating. | 2015-07-30 |
20150209514 | SYSTEM AND METHOD FOR CLOSED-LOOP PATIENT-ADAPTIVE HEMODYNAMIC MANAGEMENT - A system and method for patient-adaptive hemodynamic management is described. One embodiment includes a system for hemodynamic management including transfusion, volume resuscitation with intravenous fluids, and medications, utilizing monitored hemodynamic parameters including the described dynamic predictors of fluid responsiveness, and including an intelligent algorithm capable of adaptation of the function of the device to specific patients. | 2015-07-30 |
20150209515 | Power Injector Device and Method of Use - Automated injection system disclosed in this application advantageously provides physicians with a simplified interface for selecting fluid sources, such as saline, contrast, or a mixture of both, to inject at high pressures. The injector system may comprise a multi-use subassembly, a single-use subassembly, a fitting to fluidly connect the multi-use and single-use subassemblies, a hand held controller, a user interface, and an injector housing. | 2015-07-30 |
20150209517 | Medicament Delivery Device - A medicament delivery device has a drive mechanism that includes a first resilient member and a delay plunger rod assembly that includes a proximal plunger, a distal plunger, a chamber formed between the proximal and the distal plungers, an aperture, and a delay device in the chamber. The distal plunger is positioned and configured in relation to a hold and release mechanism such that, as the drive mechanism exerts a pressure on the medicament container, the distal plunger acts against the delay device, delaying a release of a signal generating member after a release of the drive mechanism to allow remaining contents of medicament in a medicament container to be completely expelled before the signal generating member is released. | 2015-07-30 |
20150209518 | INJECTION DEVICE FOR METERING AND DISCHARGING A FIXED DOSE OF A LIQUID PRODUCT - An injection device for metering and discharging a fixed dose of a liquid product includes a metering element or a setting button for setting and for discharging a fixed dose by means of a guide element, and a holding element having a counter guide element and a first holding member and a second holding member. In an initial position, in a retracted and in a discharged position of the metering element or the setting button, the guide element of the metering element or of the setting button engages in a guiding manner with or engages in a slotted guide system with the counter guide element of the holding element. | 2015-07-30 |
20150209519 | DISPOSABLE INJECTOR FOR INJECTING A LIQUID INTO A PATIENT - The present invention relates to a disposable automatic injector for injecting an injection liquid. | 2015-07-30 |
20150209520 | ARTICULATING APPLICATORS/INJECTORS FOR ADMINISTRATION OF LIQUID ANESTHETIC AND OTHER LIQUIDS - Disclosed are applicators and methods for injecting a liquid, such as anesthetic, into a patient with no or minimal pain. The applicator includes a coupling and a blade rotatably mounted on the coupling. The coupling is arranged to receive a cartridge in which a cannula is mounted such that the cannula extends through a proximal channel of the coupling and into a distal channel of the blade. The coupling is further arranged to secure the applicator to a source of liquid such that the liquid can be selectively introduced into and through the cannula into the tissue of the patient. The blade is thin enough for atraumatic insertion into a gingival sulcus of the patient. | 2015-07-30 |
20150209521 | Plunger Assembly Including a Plunger Rod for Advancing a Stopper Through a Syringe - Provided herein is a plunger assembly for advancing a plunger through a barrel, such as the barrel of a pre-filled syringe. The plunger assembly includes a stopper adapter defining an aperture. The stopper adapter includes a first restraining member adjacent to the aperture. The plunger assembly also includes a plunger rod having a first end, a second end, and a plunger rod head disposed adjacent the first end of the plunger rod. The plunger rod head includes a second restraining member engageable with the first restraining member of the stopper adapter. The plunger assembly is configured such that as the plunger rod head is moved axially within the aperture of the stopper adapter, the first restraining member of the stopper adapter engages the second restraining member of the plunger rod head to secure the plunger rod head within the aperture. A syringe assembly with a plunger assembly is also disclosed. | 2015-07-30 |
20150209522 | DRUG DELIVERY DEVICE AND METHOD FOR DETECTING CONTACT BETWEEN PISTON ROD AND CARTRIDGE BUNG VIA VIBRATION EXCITATION AND MONITORING - The present invention is directed to a method for detecting a contact between a drive mechanism and a bung in a drug delivery device. The bung is movably provided in a cartridge and the drive mechanism includes a piston rod and a bearing for driving the bung in a distal direction. The contact is indicated by a change in a vibration behavior, wherein the method includes the steps of inducing vibration excitations into the drug delivery device, displacing the piston rod relative to the bung such that a gap between the bearing and the bung is reduced and monitoring vibration of the drug delivery device. The invention is further directed to drug delivery device produced according to the respective method. | 2015-07-30 |
20150209523 | SUBSTANCE DELIVERY DEVICE - A substance delivery device that includes a hypodermic needle with a tube for receiving and containing a volume of a substance. The substance delivery device includes a rod, a portion of which is of a size and shape to fit within the tube of the hypodermic needle. The rod can be displaced into and within the tube to contact and apply a force to a volume of substance contained within the tube to cause, at least in part, the volume of substance to be discharged out of the tube. The substance delivery device includes a rod displacement mechanism that applies a force to the rod to cause the rod to be displaced into and within the tube. The substance delivery device also includes a needle retraction mechanism that is configured to apply a force to the hypodermic needle to cause the hypodermic needle to retract from within a patient. | 2015-07-30 |
20150209524 | Non-Axial Return Spring for Safety Needle - A needle safety device is provided having a housing, a needle assembly movably mounted within the housing and a spring for biasing the needle assembly within the housing. The needle assembly is movable along a first axis and the spring is movable along the second axis different from the first. There is also provided a lens for enhancing visualization of the flow of fluid through the needle safety device. There is further provided a safety sheath for covering a needle of the needle assembly and restraining the needle assembly against movement due to the bias of the spring. | 2015-07-30 |
20150209525 | INJECTION DEVICES - An injection device includes a forward housing, a drive housing that has a forward end configured to be attached to and detached from a rear end of the forward housing, a syringe holder mounted within the forward housing for longitudinal movement with respect to the forward housing, and a syringe with a needle that is mounted in the syringe holder. The drive housing includes a drive mechanism, and the syringe holder includes detent means for engaging the syringe to prevent or limit relative axial movement of the syringe relative to the syringe holder. | 2015-07-30 |
20150209526 | DEVICES AND METHODS FOR FORMING VASCULAR ACCESS - The invention generally relates to catheter systems and methods for guided formation of vascular access sites (such as fistulas and grafts). According to certain aspects, a catheter system for forming a vascular access site include an elongate body comprising a distal end and configured to be inserted into a first vessel. The elongate body includes an exit port along its side that is proximal to the distal end. An imaging assembly is associated with the elongate body and configured to generate image data of the first vessel and a second vessel positioned next to the first vessel. For vascular access formation, a penetrating member of the catheter system extends out of the exit port and through a wall of the first vessel and a wall of the second vessel. | 2015-07-30 |
20150209527 | FIBER OPTIC DISTAL SENSOR CONTROLLED DRUG INJECTOR - A motion-compensated injector system includes a handheld tool having a hollow shaft with a distal end for insertion into tissue of a subject. The system also includes an optical coherence tomography-based optical detection system having an optical fiber with a distal end at a fixed distance from the distal end of the hollow shaft, and an optical sensor to receive a signal from the optical fiber. The system further includes an actuator to move the hollow shaft in an axial direction, and a control unit to control the actuator. The optical detection system can monitor a distance between the distal end of the optical fiber and a reference portion of the tissue of the subject, and the control unit can control the actuator to move the hollow shaft to compensate for relative motion between the handheld tool and the portion of the tissue. | 2015-07-30 |
20150209528 | APPARATUS FOR INHALATION OF MEDICINE - Provided is an apparatus for inhalation of medicine, in which particles in a medicinal aqueous solution, in a liquid aerosol form, are converted to dry medicinal particles by removing moisture therefrom by means of an evaporation unit so as to be inhaled by means of an inhalation device, thereby allowing medicinal particles to penetrate deeply along the respiratory track to the lungs, and thus can be used in the treatment of lung diseases or a variety of other treatments using same, and in which particles of a medicinal aqueous solution in a liquid aerosol form, flowing in from an aerosol unit, are converted to dry medicinal particles by means of a moisture absorbent, thereby allowing simplification and reduction in size of the apparatus for inhalation, and in which a continuous use thereof is possible by means of a simple swap of the moisture absorbent, thereby making maintenance convenient. | 2015-07-30 |
20150209529 | Medication Delivery Apparatus and Accompanying System for the Application of Local Anesthetics to a Treatment Site and Method for Use of Same - A medication delivery apparatus and system for the application of a local anesthetic to a treatment site, such as an airway, and method for use of same are disclosed. In one embodiment of the medication delivery apparatus and system, a reservoir supplies a local anesthetic to a lower chamber of a housing wherein an ultrasonic transducer applies ultrasonic energy thereto, thereby nebulizing the local anesthetic. A control valve is interposed between a source of positive pressure air and an upper chamber of the housing to selectively apply positive air pressure to the upper chamber. Upon the application of positive air pressure, the airflow delivers the nebulized anesthetic to a patient's airway by way of a laryngoscope side port coupling, laryngoscope vacuum port coupling, or catheter coupling, for example. The application of local anesthetic, itself, in this nebulized manner mitigates gaging, chocking, aspirating, bucking and laryngospasms. | 2015-07-30 |
20150209530 | SUBSTRATES FOR VAPORIZING AND DELIVERING AN AEROSOL AGENT - Substrates configured for use with an aerosol agent delivery device to vaporize and deliver an aerosol agent to a user include a carrier and a paste applied to the carrier. The carrier is formed from a non-combustible, thermally conductive, non-toxic and non-off gassing material, such as glass, ceramic or metal. The carrier may be formed in the shape of a solid or porous disc, cupped disc, cylinder or spiral cylinder and the paste may be applied to at least one surface of the carrier. The paste composition may include a binder material, an aerosol agent, such as a therapeutic drug or nicotine, an aerosol forming agent, and an inorganic, inert filler material. The aerosol agent may be derived from an organic plant material, such as ground tobacco, coffee, tea or the like. The aerosol agent may also be provided as a liquid additive, such as liquid nicotine and tobacco flavor. | 2015-07-30 |
20150209531 | Inhaler - An inhaler comprising a housing defining a chamber to receive a strip having a plurality of blisters each containing a dose of medicament for inhalation by a user is disclosed. It comprises an actuating lever and a blister strip drive member rotatably mounted in the chamber to sequentially move each blister into a blister opening position. The blister strip drive member and the actuating lever comprise a drive gear and a drive gear element, respectively, that cooperate to effect rotation of the blister strip drive member in response to rotation of the actuating lever. The drive gear and drive gear element are disposed on the outside of the housing remote from the chamber. | 2015-07-30 |
20150209532 | METHOD OF DETECTING ENDOTRACHEAL TUBE MISPLACEMENT - A method of intubating a subject is disclosed. The method comprises inserting an endotracheal tube into the tracheal airway of the subject; inflating a cuff associated with the endotracheal tube within the airway below the vocal cords; measuring a level of at least one measure being indicative of leakage of secretion past the cuff to the lungs; comparing the level of the measure with an optimal level of the measure; and adjusting inflation of the cuff based on the comparison so as to generally minimize leakage of secretion from above the cuff to the lungs, while minimizing pressure associated damages to the airway. The measure(s) can be carbon dioxide concentration, a proxy measure from which such concentration can be inferred, or the level of one or more additives delivered to a subject during intubation. | 2015-07-30 |
20150209533 | RESPIRATORY ASSISTANCE DEVICE, NASAL APPLIANCE AND RESPIRATORY ASSISTANCE MASK - A device for respiratory assistance of a patient includes a tubular element forming a main channel for connection by its distal end to a respiratory tract of the patient, the main channel connecting the patient's respiratory system by its proximal end to the outside, the device further including at least one auxiliary channel for injecting a jet or jets of respirable gas through one or more distal outlet holes of the auxiliary channel or channels, the one or more outlet holes opening-out in the main channel in the vicinity of the distal end of the latter, deflecting elements for deflecting the jets of respirable gas toward the interior of the main channel. The diameter of the outlet hole of each auxiliary channel is less than 150 microns. The outlet holes of the device are shaped as an annular or semi annular strip resulting from assembling/uniting together certain distal outlet holes. | 2015-07-30 |
20150209534 | COMPRESSIBLE CONNECTOR FOR AN INNER CANNULA - A tracheal tube assembly includes an outer cannula configured to be positioned in a patient airway and an inner cannula configured to be disposed inside the outer cannula. The tracheal tube assembly further includes a flange member secured about the outer cannula, and an outer cannula connector coupled to a proximal end of the outer cannula. The inner cannula includes a compressible proximal end region that is compressed while secured inside the outer cannula connector. | 2015-07-30 |
20150209535 | ORAL SUCTION DEVICE - An oral suction device includes a suction catheter having a suction portion at a first end, a shell surrounding the suction portion, and a suction tubing connector on a second end opposite the first end. The shell includes a hydrogel. | 2015-07-30 |
20150209536 | ENDOTRACHEAL TUBE WITH DUAL PORT SUBGLOTTIC SECRETION SUCTIONING - An endotracheal tube assembly comprises an elongate tube having an outer wall defining an outer surface, the tube defining an elongate central lumen and an elongate suction lumen, and an inflatable cuff attached on a distal end portion of the elongate tube. The elongate tube defines a first suction opening having a normal vector parallel to a tangent to an outer circumference of a transverse cross-section of the outer wall of the tube next to said first suction opening, the first suction opening being in fluid communication with the suction lumen. | 2015-07-30 |
20150209537 | MEDICO-SURGICAL TUBE ASSEMBLIES - A tracheostomy tube assembly has a flange arrangement ( | 2015-07-30 |
20150209538 | LARYNGEAL MASK WITH A BITE ABSORBING CONNECTOR - A laryngeal mask insertable into a patient, an airway tube of the laryngeal mask having a bore extending from a proximal to a distal end of the airway tube, a connector provided at the proximal end of the airway tube, the connector comprising a connector body with a longitudinal bore, at least two wall portions extending longitudinally from a first continuous wall to a second continuous wall, and two parallel and opposite longitudinal wall cut-away portions intermediate the at least two wall portions, the length of the longitudinal wall cut-away portions being greater than the length of the first continuous wall. | 2015-07-30 |
20150209539 | PATIENT INTERFACE SYSTEMS - A patient interface system for delivery of a supply of air at positive pressure to the entrance of a patient's airways for treatment of sleep disordered breathing includes an air delivery tube connected to a flexible portion of a plenum; a vent structure having sufficient rigidity to support its own weight under gravity and/or not to block or fold under tube movement or tube drag; and a patient interface structure. The patient interface structure includes a seal forming structure arranged on a top portion of the plenum; and a seal positioning and stabilizing structure connected to a flexible portion of the plenum. The seal-forming structure is substantially decoupled from a tube drag force. | 2015-07-30 |
20150209540 | PATIENT INTERFACE WITH CUSHION FOR RED MARK PREVENTION - The present invention relates to a patient interface and a patient interface system comprising a responsive material and a method for preventing the formation of red marks due to wearing a patient interface ( | 2015-07-30 |
20150209541 | NASAL INTERFACES FOR RESPIRATORY THERAPY - Patient interfaces for respiratory therapy in the form of nasal interfaces or nasal masks include features that enhance or provide lateral stability of the interface. At least some of the embodiments provide multiple facial contact points or areas located in the general areas of the user's cheeks and/or upper lip. Some embodiments of the nasal interfaces provide advantageous sealing characteristics. The nasal interfaces may provide a controlled expiratory flow to reduce noise. Some embodiments include nasal pillows instead of or in addition to nasal prongs. The nasal pillows can have exhaust vents or can change in length in response to a pressure level within the nasal pillow. | 2015-07-30 |
20150209542 | NASAL CANNULA - A nasal cannula arrangement for use as part of systems for delivery respiratory gases to a patient is disclosed. The nasal cannula arrangement includes a manifold part adapted to receive gases from a delivery conduit. The manifold includes one but preferably a pair of prongs extending upward and curving towards the rear of the manifold. The prongs are inserted into the nostrils of the patient and deliver gases to a patient. The prongs have a cut out on the rear side of the prongs. The cut out forms a gases outlet in the prongs and are shaped such that the area of the cut out area is greater than the cross sectional area of the prongs at the entry point to the prongs. | 2015-07-30 |
20150209543 | DEVICE FOR SECURING A BREATHING TUBE AND METHOD OF MANUFACTURING THE SAME - A device for securing a tube includes a strip defining upper and lower surfaces and an attachment array on the lower surface thereof. First and second attachment members are coupled to the strip adjacent end portions thereof and define attachment arrays facing in the same direction as the upper surface of the strip. A third attachment member defines opposed surfaces having respective attachment arrays. A first of the attachment arrays is releasably engaged with the attachment array of the strip. The strip is configured to wrap around a tube with the attachment arrays of the attachment members and a second attachment array of the third attachment member releasably engaged with a strap member for securing the tube therebetween. The first and second attachment arrays of the third attachment member are configured such that the first attachment array defines a greater holding force than the second attachment array. | 2015-07-30 |
20150209544 | OXYGEN CONCENTRATOR - Branch flow channels configured respectively to supply compressed air to two sieve beds respectively are provided with air supply valves each including a diaphragm valve and an electromagnetic pilot valve for driving the diaphragm valve and configured to open and close the respective branch flow channels, a pilot flow channel configured to supply pilot air to the electromagnetic pilot valves is branched from the branch flow channels, and a check valve for preventing pilot air from flowing reversely is provided in the pilot flow channel. | 2015-07-30 |
20150209545 | Delivery Apparatus and Accompanying System for the Application of a Medical Agent to a Treatment Site and Method for Use of Same - A medication delivery apparatus and system for the application of a medical agent to a treatment site, such as an airway, and method for use of same are disclosed. In one embodiment of the medication delivery apparatus and system, a reservoir supplies a medical agent to a lower chamber of a housing wherein an ultrasonic transducer applies ultrasonic energy thereto, thereby nebulizing the medical agent. A control valve is interposed between a source of positive pressure air and an upper chamber of the housing to selectively apply positive air pressure to the upper chamber. Upon the application of positive air pressure, the airflow delivers the nebulized medical agent to a target location, such as the airway. | 2015-07-30 |
20150209546 | Anesthesia Machine - Disclosed is an anesthesia gas delivery device and methods of use therefor. The device comprises an aluminum cover plate, a gas inlet for a carrier gas, a gas outlet for a diluent anesthetic gas, a gas corridor in fluid communication with and extending between the gas inlet and the gas outlet, at least four ultrasound acoustic sensors, at least 2 thermistors, a reservoir comprising a reservoir housing for a liquid inhalational anesthetic, a controller, a graphical user interface, and means for transferring a sample of a liquid inhalational anesthetic from the reservoir to the gas corridor. Methods of providing anesthesia to a subject using the device are also disclosed. These methods comprise using ultrasound and temperature data to determine anesthetic gas velocity, composition and concentration. | 2015-07-30 |
20150209547 | FLEXIBLE TIP CATHETER WITH EXTENDED FLUID LUMEN - A lumen extension member is provided for a catheter having a catheter body and an elongate electrode coupled to the catheter body. The elongate electrode defines an electrode lumen extending therethrough. The lumen extension member is positioned within the electrode lumen and is coupled to the catheter body. The lumen extension member includes a tubular member including a sidewall and at least one opening that extends through the sidewall. | 2015-07-30 |
20150209548 | DIRECTIONAL SUBINTIMAL ACCESS FOR CHEMICAL AGENT DELIVERY - Various devices, systems, and methodologies are disclosed for delivering a chemical agent to tissue, e.g., for delivering an anti-restenotic agent to tissue comprising a wall of a blood vessel. In one embodiment of the disclosure, a delivery member is disclosed comprising a body that includes a plurality of discrete, separable sections, wherein each section includes a housing defining an internal cavity, and a penetrating member that extends from the housing. | 2015-07-30 |
20150209549 | NEUROSURGICAL APPARATUS AND METHOD - A method for delivering fluid to the brain of a subject using an intraparenchymal catheter, the method comprising the step of inserting the catheter into the brain using a posterior to anterior approach and methods of treating neurodegenerative disorders using this delivery method, as well as methods for delivering fluid to an elongate structure of the brain using an intraparenchymal catheter, the method comprising the step of inserting a catheter into the brain along an insertion axis that is substantially aligned with a long axis of the elongate structure. | 2015-07-30 |
20150209550 | CATHETER HAVING DISSOLVABLE PORTIONS AND RELATED METHODS - A catheter has a distal tip having a primary opening formed as the distal opening formed along the axis of the catheter. One or more secondary openings are formed through a side wall of the catheter proximal of the distal opening. A dissolvable portion made up of a resorbable material is disposed within the one or more secondary openings and aligned with the outer surface of the catheter so that the outer surface of the catheter and outer surface of the dissolvable portion combine to present a substantially smooth outer surface. When the catheter distal tip is arranged in a patient's blood vessel, the resorbable material dissolves, so that the fluid delivered by the catheter can exit the catheter through the primary and secondary openings. In some embodiments the secondary openings can be contiguous with the primary opening. | 2015-07-30 |
20150209551 | MRI COMPATIBLE ABLATION CATHETER SYSTEM INCORPORATING DIRECTIONAL HIGH-INTENSITY ULTRASOUND FOR TREATMENT - A magnetic resonance compatible catheter. The catheter incorporates directional high intensity ultrasound. The catheter may include imaging coils visible through magnetic resonance imaging. The location and placement of the catheter may be controlled by steering wires within lumen in the catheter guided by the location information from the magnetic resonance imaging. | 2015-07-30 |
20150209552 | MEDICAL DEVICE SECUREMENT SYSTEM AND METHOD - A medical device securement system is configured to secure medical devices such as catheters in place. The securement system includes an anchor pad that attaches to a patient's skin. A malleable support base is attached to an upper surface of the anchor pad. The support base has front and back inclined surfaces that are separated by an offset surface that extends generally normal to both of the inclined surfaces. A spot of adhesive is applied to one or more of the inclined surfaces. A catheter assembly includes a connector having a first connector portion with a diameter larger than an adjacent second structure. The catheter assembly is attached to the support base with the first connector portion engaged with and supported by the back inclined surface, and the second connector portion engaged with and supported by the front inclined surface. | 2015-07-30 |
20150209553 | DRUG RELEASING COATINGS FOR MEDICAL DEVICES - Medical devices are provided for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. The additive has a hydrophilic part and a hydrophobic part and the therapeutic agent is not enclosed in micelles or encapsulated in particles or controlled release carriers. | 2015-07-30 |
20150209554 | DRUG RELEASING COATINGS FOR BALLOON CATHETERS - Balloon catheters, methods for preparing balloon catheters, and uses of balloon catheters are disclosed. The balloon catheter includes an elongate member, an expandable balloon, and a coating layer overlying an exterior surface of the expandable balloon. The coating layer includes a total drug load of a hydrophobic therapeutic agent and a combination of additives including a first additive and a second additive. The hydrophobic therapeutic agent is paclitaxel, rapamycin, or paclitaxel and rapamycin. The first additive is a surfactant. The second additive is a chemical compound having one or more hydroxyl, amino, carbonyl, carboxyl, acid, amide, or ester groups. | 2015-07-30 |
20150209555 | COATINGS FOR MEDICAL DEVICES - A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which includes an amphiphilic polymer or copolymer, in embodiments polyethylene glycol, having a substantially water-insoluble therapeutic agent dispersed therein. In some embodiments, the coating may also include iodine. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue. | 2015-07-30 |
20150209556 | FLEXIBLE HIGH-PRESSURE ANGIOPLASTY BALLOONS - Flexible high-pressure angioplasty balloons are disclosed herein which utilize an inflatable balloon positioned upon the catheter and a supporting structure secured over or along the catheter at a first location proximal to the balloon and at a second location distal to the balloon. Inflation of the balloon reconfigures the supporting structure to urge the first location and the second location towards one another thereby inhibiting longitudinal elongation of the balloon relative to the catheter. The supporting structure may surround, support, or otherwise extend over the entire length of the balloon and allows for the balloon to retain increased flexibility which enables the balloon to bend or curve even at relatively high inflation pressures. | 2015-07-30 |
20150209557 | SYSTEMS FOR BLOOD VESSEL DILATATION AND VISUALIZATION - A percutaneous transluminal angioplasty (PTA) catheter may be configured to perform vein expansion and occlusion. A infusion port ( | 2015-07-30 |
20150209558 | Articulating Balloon Catheter and Method for Using the Same - Articulating balloon catheters and methods of using articulating balloon catheters are described herein. An embodiment of an articulating balloon catheter comprises an elongate member and a balloon. The balloon is attached to the elongate member and is adapted to move between a deflated configuration and an inflated configuration. The balloon has a proximal portion, a distal portion, and an articulating region disposed between the proximal portion and the distal portion. The articulating region of the balloon is configured to provide articulation between the proximal portion and the distal portion of the balloon. | 2015-07-30 |
20150209559 | WEEPING BALLOON CATHETER WITH DRUG DELIVERY BALLOON IN FLUID COMMUNICATION WITH COMBINATION LUMEN - A weeping balloon catheter includes a catheter having an elongate tubular body defining an inflation lumen and a combination lumen that terminates at an open distal end of the elongate tubular body. A dilation balloon is disposed at a distal end of the elongate tubular body and is in fluid communication with the inflation lumen. A drug delivery balloon is disposed at least partially over the dilation balloon and includes at least one drug release opening through an outer wall of the drug delivery balloon. The drug delivery balloon is in fluid communication with the combination lumen through a sidewall opening of the elongate tubular body. | 2015-07-30 |
20150209560 | OCCLUSION PERFUSION CATHETER - Catheters for occluding, visualizing, irrigating, evacuating, and delivering agents to a treatment area are disclosed. The catheters comprise a catheter body comprising five lumens, first and second occlusion balloons coupled to the catheter body, an optional space-occupying balloon coupled to the catheter body and disposed between the first and second occlusion balloons, and an optional visualization means that enables visualization between the first and second occlusion balloons. Methods for using these catheters are also disclosed. A method comprises inflating the first and second occlusion balloons, inflating the space-occupying balloon, allowing fluid to exit via an evacuation lumen, optionally irrigating or aspirating to facilitate fluid exit via said lumen, and delivering an agent to a treatment area via the agent lumen. | 2015-07-30 |
20150209561 | Wearable Topical Drug Delivery Device - The present invention provides a wearable drug delivery device that is adapted to be worn by a user. The device can be provided as strips of a porous mesh material for wrapping around the body or as wearable garments that are impregnated with natural medications and stimulants. The materials may be wrapped around the desired portion of the body such as the forehead, chest, hands, wrists, knees, or feet in a variety of ways. The material may be impregnated with a multitude of natural medications and stimulants including iodine, caffeine, hormones, pain medication, diet drugs, argentine, taurine, vitamin B, vitamin D, ginseng, and green tea, among others. The present invention enables the localized application of topical medications, thereby providing direct treatment to the area of the body in need. | 2015-07-30 |
20150209562 | TREATMENT OF CAVITIES IN A HUMAN BODY - Apparatus and methods are described, including apparatus for treating a cavity in a human body, the apparatus including a delivery tube. A barrier device has a collapsed and an expanded configuration, the barrier device moving from the collapsed to the expanded configuration upon being deployed from the delivery tube. A pushing element, slidably disposed within a lumen of the delivery tube, deploys the barrier device from the delivery tube by pushing the barrier device. One or more barrier-deployment elements are coupled to the barrier device and to the pushing element, the barrier-deployment elements being configured to conformingly contact the barrier device with tissue surrounding the cavity. The barrier device is configured to isolate the cavity from surrounding body fluid that is between the barrier device and the pushing element, following deployment of the barrier device from the delivery tube. Other applications are also described. | 2015-07-30 |
20150209563 | DELIVERY DEVICES AND METHODS FOR SKIN AUGMENTATION - The present invention provides, inter-alia, applicators comprising an array of microneedles for administration of a composition comprising a biocompatible ceramic material effective in augmentation of skin. In particular, the applicators and methods of the present invention are aimed at filling the undesired lines, wrinkles, depressed scars and folds of a subject's skin and restoring youthful fullness to the skin. | 2015-07-30 |
20150209564 | ULTRASOUND DEVICE AND THERAPEUTIC METHODS - The present invention is directed to an ultrasound device for use in implementing therapeutic treatments and transdermal analyte delivery. The device includes a piezoelectric transducer that efficiently and safely converts electrical energy to ultrasonic waves, and has a unique structure including a piezoelectric element positioned between two opposing, flexible concave covers. The device may be used for various therapeutic purposes including wound healing, tissue stimulation and transdermal analyte delivery. The invention is further directed to a novel analyte delivery system including the ultrasound device and an encapsulated analyte. | 2015-07-30 |
20150209565 | APPARATUS FOR EXTRACTING AND RE-INJECTING ADIPOSE TISSUE - Example kits of parts, apparatus and methods for liposuction and lipofilling of adipose tissue are disclosed. An example kit includes an extraction unit comprising a liposuction device having a cannula coupled to a handpiece, which imparts movement to an inlet end of the cannula. The example kit includes a separation unit, a re-injection unit, a vacuum pump, a re-injection pump, and tubing for connecting the elements of the kit of parts to form an apparatus for liposuction and lipofilling of adipose tissue. The example handpiece imparts to the inlet end of the cannula a vibrational movement comprising a first, linear component and a second, orbital component. The example kit also includes a three-way valve having an aspiration position to bring a retentate volume of the separation unit in communication with the re-injection pump, and an injection position to bring the re-injection pump in communication with the lipofilling device. | 2015-07-30 |
20150209566 | METHOD AND COMPOSITION FOR HYPERTHERMALLY TREATING CELLS - A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells. | 2015-07-30 |
20150209567 | Antimicrobial Straw - A polymeric tubular conduit including a polymeric tubular conduit wall having an outer tubular layer coaxially overlaying an inner tubular layer which defines a continuous tubular passage along a polymeric tubular conduit length of the polymeric tubular conduit; whereby the outer tubular layer, the inner tubular layer, or combinations thereof, include an amount of antimicrobial agent. The amount of antimicrobial agent can be sufficient to kill or inhibit growth of microorganisms in contact with a corresponding polymeric tubular conduit wall external surface, polymeric tubular conduit wall internal surface, or combinations thereof, of the polymeric tubular conduit wall. | 2015-07-30 |
20150209568 | Arrangement in a Medical Connector Device - A medical transfer and connecting device ( | 2015-07-30 |
20150209569 | Luer Connectors - Luer connector including a primary Luer male connector, having a secondary female section extending from a top distal part of the primary Luer male connector back towards a proximal part thereof, the primary Luer male connector including a first inner fluid flow channel extending from a proximal end thereof to the secondary female section, the primary Luer male connector being configured to mate with a primary Luer female connector having a secondary male section including a second inner fluid flow channel. | 2015-07-30 |
20150209570 | COMPRESSION ELEMENT DRIVEN FLUID DELIVERY APPARATUS - The present invention relates to a medical apparatus, methods and system for fluid medication delivery. The apparatus has a drive mechanism module and a fluid container engaged to the drive mechanism. The drive mechanism includes a resilient member compressed to act against a gasket movably disposed in the fluid container. When extending to its original shape, the resilient member pushes the gasket to move inside the fluid container to eject the fluid out of the fluid container. The fluid container is connected to a flow restrictor tube that allows a predetermined flow rate of medication to be infused or injected to a patient. | 2015-07-30 |