32nd week of 2009 patent applcation highlights part 37 |
Patent application number | Title | Published |
20090197161 | BATTERY ASSEMBLY - A battery assembly includes a plate shaped first collector electrode provided between first and second secondary batteries for electrically connecting the first and second secondary batteries; a second collector electrode of a polarity different from the first collector electrode, provided on a surface opposite to the surface of the first secondary battery on which the first collector electrode is provided; a first terminal portion provided at the first collector electrode and connected to a first conductive member; and a second terminal portion provided at the second collector electrode and connected to a second conductive member; wherein the first and second terminal portions are arranged staggered in a direction of stacking. | 2009-08-06 |
20090197162 | Stack type battery - A stack type battery has positive electrode current collector tabs ( | 2009-08-06 |
20090197163 | High rate primary lithium battery with solid cathode - A safe high rate primary lithium battery with solid cathode and a lithium anode is provided, having a high rate of discharge and higher energy density due to the lithiated cathode materials contained therein. | 2009-08-06 |
20090197164 | PLATED STEEL PLATE FOR CELL CAN, BATTERY, ALKALINE DRY BATTERY - The invention provides a plated steel plate for a cell can in which stable and good electrical contact can be provided on an outer surface of the cell can, and the evolution of gas within a battery can be suppressed by reducing damage to a plated surface of the steel plate when the cell can is formed by drawing press. In this manner, it is possible to provide a battery and an alkaline dry battery that can realize stable electrical contact with devices and reduce the evolution of gas. In a plated steel plate | 2009-08-06 |
20090197165 | ALKALINE BATTERY - An alkaline battery includes: a battery can ( | 2009-08-06 |
20090197166 | BATTERY MODULE CASE - A battery module case includes: a first case in which a plurality of first battery cells are held in a stacked state and which includes a first plate formed with a first cutout portion from which an end surface of one of the first battery cells which is adjacent to the first plate is exposed; and a second case in which a plurality of second battery cells are held in a stacked state and which includes a second plate confronting the first plate and formed with a second cutout portion from which an end surface of one of the second battery cells which is adjacent to the second plate is exposed. When the first plate and the second plate are arranged adjacent to each other, the first cutout portion and the second cutout portion define a passage in which cooling fluid can flow between the first plate and the second plate. | 2009-08-06 |
20090197167 | Fluorinated Additives For Lithium Ion Batteries - The usability of certain fluorinated organic compounds which have aromatic radicals, C═C double bonds, C═O groups or organosilicon groups as an additive for Li ion batteries is disclosed. | 2009-08-06 |
20090197168 | STORAGE ELEMENT - There is provided a battery device having a high operating voltage and a low capacity degradation rate. The battery device comprising: a positive electrode having at least a positive electrode active material layer and a positive electrode collector; a negative electrode; a separator; and an organic electrolytic solution, wherein the positive electrode active material layer contains non-porous carbon having a specific surface area of 500 m | 2009-08-06 |
20090197169 | ALKALINE BATTERY - An alkaline battery comprising a positive electrode, a negative electrode, a separator disposed between the positive electrode and the negative electrode; and an alkaline electrolyte, wherein the positive electrode includes manganese dioxide and graphite; the cumulative pore volume of pores with diameters of 3 to 5 nm in the manganese dioxide is X (cm | 2009-08-06 |
20090197170 | MAXIMIZATION OF ACTIVE MATERIAL TO COLLECTOR INTERFACIAL AREA - A current collector for a battery in an implantable medical device is presented. The current collector comprises a conductive layer which includes a first surface and a second surface. A plurality of apertures are formed in the conductive layer such that a surface area of the conductive layer with the plurality of apertures to a surface area without the plurality of apertures is greater than 0.65. | 2009-08-06 |
20090197171 | ELECTRIC STORAGE DEVICE - An electric storage device | 2009-08-06 |
20090197172 | METHOD FOR MANUFACTURING LITHIUM ION SECONDARY BATTERY - A method for manufacturing a lithium ion secondary battery comprises the step of sintering a laminate sandwiched by setters disposed on both sides of the laminate having only interfaces between an electrolyte green sheet and a positive electrode green sheet and/or a negative electrode green sheet. A lithium ion secondary battery manufactured by the method described above is also provided. | 2009-08-06 |
20090197173 | COMPOSITE CARBONATE AND METHOD FOR PRODUCING THE SAME - The present invention provides a nickel atom-, manganese atom- and cobalt atom-containing composite carbonate that is high in specific surface area and large in tap density, and useful as a raw material for producing a lithium nickel manganese cobalt composite oxide to be used in a positive electrode active material for use in a lithium secondary battery, and provides a method for industrially advantageously producing the composite carbonate. The composite carbonate includes nickel atoms, manganese atoms and cobalt atoms, and has an average particle size of 20 μm or more and 40 μm or less, a BET specific surface area of 50 to 130 m | 2009-08-06 |
20090197174 | Synthesis of Electroactive Crystalline Nanometric LiMnPO4 Powder - The invention describes a method for making nano-sized crystalline LiMnPO | 2009-08-06 |
20090197175 | ELECTRIC STORAGE DEVICE - An electric storage device | 2009-08-06 |
20090197176 | ANODE ACTIVE MATERIAL, AND ANODE AND LITHIUM BATTERY CONTAINING THE SAME - An anode active material including a tin (Sn)-cobalt (Co) intermetallic compound, titanium (Ti), and carbon (C). The anode active material can include indium (In), niobium (Nb), germanium (Ge), molybdenum (Mo), aluminum (Al), phosphorus (P), gallium (Ga), bismuth (Bi), and/or silicon (Si). The anode active material can be included in an anode, and the anode can be included in lithium battery. | 2009-08-06 |
20090197177 | LITHIUM ION SECONDARY BATTERY AND A METHOD FOR MANUFACTURING THE SAME - A method for manufacturing a lithium ion secondary battery includes steps of preparing a green sheet comprising at least one of lithium ion conductive inorganic powder and inorganic powder which becomes lithium ion conductive when it is heat treated; producing a thin film solid electrolyte by heat treating the green sheet; laminating an electrode green sheet comprising an active material on at least one surface of the thin film solid electrolyte; and heat treating the electrode green sheet at a temperature which is lower than a temperature at which the solid electrolyte is heat treated. | 2009-08-06 |
20090197178 | MANUFACTURE OF LITHIUM ION SECONDARY BATTERY - A method for manufacturing a lithium ion secondary battery which can realize strong bonds between layers and a high ion conducting property within the layers by sintering as the layers constituted of a solid electrolyte layer, a positive electrode layer, and a negative electrode layer are sintered and bonded mutually is provided. And the lithium ion secondary battery manufactured by the aforementioned method is also provided. | 2009-08-06 |
20090197179 | NON-AQUEOUS ELECTROLYTE BATTERY AND NEGATIVE ELECTRODE, AND METHOD FOR MANUFACTURING THE SAME - A non-aqueous electrolyte battery includes a positive electrode, a negative electrode having a negative electrode active material layer provided on a negative electrode collector and a non-aqueous electrolyte, wherein the negative electrode active material layer contains a polyvinylidene fluoride-containing binder and a nano ceramic particle having a primary particle size of not more than 100 nm; and the binder and the nano ceramic particle are complexed. | 2009-08-06 |
20090197180 | SPACERS BETWEEN TABS OF ELECTRODE PLATES IN AN ELECTROCHEMICAL CELL FOR AN IMPLANTABLE MEDICAL DEVICE - A battery (or cell) in an implantable medical device is presented. The cell includes a first electrode element with a first tab extending therefrom and a second electrode element with a second tab extending therefrom. A spacer is coupled to the first and second tabs. | 2009-08-06 |
20090197181 | NON-AQUEOUS ELECTROLYTE BATTERY AND METHOD OF MANUFACTURING THE SAME - [Problem] A non-aqueous electrolyte battery is provided that shows good cycle performance and good storage performance under high temperature conditions and exhibits high reliability even with a battery configuration featuring high capacity. A method of manufacturing the battery is also provided. | 2009-08-06 |
20090197182 | SOLID STATE BATTERY - A solid state battery comprising: a solid electrolyte; a positive electrode containing an active material; and a negative electrode containing an active material is provided. The solid electrolyte is disposed between the positive electrode and the negative electrode. At least one of the positive electrode active material and the negative electrode active material contains a metal oxide. | 2009-08-06 |
20090197183 | SOLID BATTERY AND A METHOD FOR MANUFACTURING AN ELECTRODE THEREOF - A solid battery includes at least either one of a positive electrode and a negative electrode comprising bars of an active material of the electrode and bars of a solid electrolyte of the electrode arranged alternately in such a manner that each of the bars of the active material of the electrode is disposed adjacent to each of the bars of the solid electrolyte of the electrode, and a solid electrolyte constituting a separator and having a plane to which the bars of the active material and the bars of the solid electrolyte of the electrode are disposed in a crossing direction. There is also provided a method for manufacturing an electrode of such solid battery. | 2009-08-06 |
20090197184 | NON-AQUEOUS ELECTROLYTIC SOLUTION BATTERY AND NON-AQUEOUS ELECTROLYTIC SOLUTION COMPOSITION - A non-aqueous electrolytic solution battery includes a positive electrode, a negative electrode and an electrolytic solution, wherein the non-aqueous electrolytic solution contains two kinds of halogenated cyclic carbonates containing a different halogen element from each other. | 2009-08-06 |
20090197185 | DOCUMENT RECORDING METHOD AND APPARATUS - A document recording method for recording a document on a microfilm, the document including a series of pages, a format of which is specified so as to include at least a page representing commencement, a page representing an original, and a page representing conclusion. The method includes recording all or a portion of the series of pages on the microfilm in a hologram format that is obtained by interference between object light and reference light. | 2009-08-06 |
20090197186 | OPTICAL DEVICES RESPONSIVE TO BLUE LASER AND METHOD OF MODULATING LIGHT - An optical device comprising a photorefractive composition configured to be photorefractive upon irradiation by a blue laser. The photorefractive composition comprises a polymer comprising a repeating unit including at least a moiety selected from the group consisting of the formulas (Ia), (Ib) and (Ic), as defined herein. | 2009-08-06 |
20090197187 | HOLOGRAM FABRICATION PROCESS AND FABRICATED HOLOGRAM - The invention provides a hologram in which a visually unidentifiable microtext or other micropattern of the order of 10 μm is recorded, and a process for the fabrication of the same. A volume hologram recording material | 2009-08-06 |
20090197188 | Method for a multiple exposure beams lithography tool - An aspect of the present invention includes a method for patterning a workpiece covered at least partly with a layer sensitive to electromagnetic radiation by simultaneously using a plurality of exposure beams. In an example embodiment it is determined if any of the beams have an actual position relative to a reference beam which differs from its intended position. An adjustment of the exposure dose for a wrongly positioned beam is performed if said beam is printed at en edge of a feature. Other aspects of the present invention are reflected in the detailed description, figures and claims. | 2009-08-06 |
20090197189 | FOCUS MEASUREMENT METHOD AND METHOD OF MANUFACTURING A SEMICONDUCTOR DEVICE - In a focus measurement method and a method of manufacturing a semiconductor device relating to the present invention, a focus value is obtained by using a fluctuation where shrinkage of a resist pattern by an electron beam irradiation depends upon the focus value. In the case of obtaining the focus value, the shrinkage of the resist pattern for a focus measurement formed by exposure to be subject for a focus value measurement is measured. The focus value corresponding to the shrinkage is obtained from the pre-obtained focal dependency of the shrinkage. A focal shift length can be defined from a difference between the focus value and a predetermined best focus value. | 2009-08-06 |
20090197190 | TWO-COMPONENT DEVELOPER, REPLENISHING DEVELOPER, AND IMAGE-FORMING METHOD USING THE DEVELOPERS - An object of the present invention is to suppress the adhesion of a carrier to an image bearing member and the generation of a flaw in the surface layer of the image bearing member, and to improve the dot reproducibility of an electrostatic latent image, and soon. The object is achieved by a two-component developer containing a magnetic carrier, which contains resin-containing magnetic particles, in which the packed bulk density ρ1 is 0.80 to 2.40 and ρ1/ρ2 (ρ2 represents true density) is 0.20 to 0.42 of the porous magnetic core particles, and a specific resistance of the porous magnetic core particles, an average breaking strength of the magnetic carrier and a toner surface tension constant in a 45-vol % aqueous solution of methanol measured by a capillary suction time method fall into the specific range, respectively. | 2009-08-06 |
20090197191 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR HAVING EXCELLENT STABILITY IN TERMS OF ELECTRICAL PROPERTIES AND INTERLAYER ADHESION STRENGTH AND ELECTROPHOTOGRAPHIC IMAGING APPARATUS EMPLOYING THE SAME - An electrophotographic photoreceptor including an undercoat layer and a photosensitive layer that are sequentially formed on an electrically conductive substrate, wherein the undercoat layer has a structure in which metal oxide particles and dialkylcitrate-chelated zirconate represented by Formula 1, illustrated below, are dissolved or dispersed in a binder resin, and an electrophotographic imaging apparatus including the electrophotographic photoreceptor: | 2009-08-06 |
20090197192 | MAGNETIC TONER - A magnetic toner having magnetic toner particles containing at least a binder resin and a magnetic material, wherein, in the test of dissolution level of the magnetic material, the dissolution percentages S | 2009-08-06 |
20090197193 | TONER - To provide a toner which has superior low-temperature fixing performance, high-temperature anti-offsetting properties and developing performance and may cause neither melt sticking of toner to photosensitive member nor turn-up of cleaning blade. The toner contains at least a binder resin, a colorant and a wax, and the wax is characterized by i) being an oxidized hydrocarbon wax, ii) having a hydroxyl value of from 5 mgKOH/g or more to 150 mgKOH/g or less, and iii) having, in molecular weight distribution measured by gel permeation chromatography of tetrahydrofuran-soluble matter, a main peak within the range of molecular weight of from 200 or more to 600 or less, and a component with a molecular weight of 700 or more in a content of 3% by mass or less. | 2009-08-06 |
20090197194 | CARRIER CORE MATERIAL FOR ELECTROPHOTOGRAPHIC DEVELOPER, CARRIER AND ELECTROPHOTOGRAPHIC DEVELOPER USING THE CARRIER - There are adopted: a carrier core material for an electrophotographic developer, including Mg, Ti and Fe as main components, and containing Fe, Mg and Ti in contents of 52 to 66% by weight, 3 to 12% by weight and 0.2 to 12% by weight, respectively; an electrophotographic developer carrier prepared by coating with a resin the surface of the carrier core material; and an electrophotographic developer using the carrier. | 2009-08-06 |
20090197195 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING METHOD - Provide is an electrophotographic photoreceptor exhibiting excellent evenness of halftone images together with fine line reproduction, and an image forming method thereof, as to a photoreceptor in which an oxytitanium phthalocyanine pigment having a maximum diffraction peak at a Bragg angle (2θ±0.2°) of 27.2° in CuKα X-ray diffraction. Also disclosed is an electrophotographic photoreceptor possessing a body having cylindrical conductive support provided thereon photosensitive layer containing oxytitanium phthalocyanine pigment having maximum diffraction peak at a Bragg angle (2θ±0.2°) of 27.2° in CuKα X-ray diffraction, and flanges jointed at both ends of the body, wherein at least one of flanges is fitted with driving shaft having drive hole having at least 3 sides, and a ratio B/A of cross-sectional area B of engaging part of rotation shaft to rotate the electrophotographic photoreceptor with respect to cross-sectional area A of the drive hole is 0.890-0.998. | 2009-08-06 |
20090197196 | IMAGING MEMBER AND METHODS OF FORMING THE SAME - The presently disclosed embodiments are directed to charge transport layers useful in electrostatography. More particularly, the embodiments pertain to an improved imaging member having a charge transport layer comprising a top layer and a bottom layer, wherein the layers have varying concentrations of high quality N,N,N′N′-tetra(4-methylphenyl)-(1,1′-biphenyl)-4,4′-diamine to provide tunable discharge rate. | 2009-08-06 |
20090197197 | RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN - A resist composition comprising a base component (A) which exhibits changed solubility in an alkali developing solution under action of acid, an acid-generator component (B) which generates acid upon exposure, and a nitrogen-containing organic compound (D), the nitrogen-containing organic compound (D) including a nitrogen-containing polymeric compound (D1) having a structural unit (d0) containing a nitrogen atom in the side chain thereof. | 2009-08-06 |
20090197198 | PHOTOSENSITIVE MOLECULAR COMPOUND AND PHOTORESIST COMPOSITION INCLUDING THE SAME - Disclosed are a photosensitive compound containing oxime group which is directly decomposed by exposure to light, which is a molecular resist whose size is smaller than conventional polymer for photoresist, and a photoresist composition including the same. The photosensitive molecular compound has a structure represented by a following formula. | 2009-08-06 |
20090197199 | MATERIAL FOR FORMING RESIST PROTECTIVE FILM AND METHOD FOR FORMING RESIST PATTERN USING SAME - In the liquid immersion lithography process, by simultaneously preventing deterioration of a resist film and deterioration of an immersion liquid employed during liquid immersion lithography which uses various immersion liquids, including water, resistance to post exposure delay of the resist film can be improved without increasing the number of processes, thereby making it possible to form a high resolution resist pattern using liquid immersion lithography. Using an alkaline soluble polymer, a crosslinking agent, and a solvent capable of dissolving them as at least constituent component, a composition is prepared and a protective film is formed on the surface of the resist film to be used, using the composition. | 2009-08-06 |
20090197200 | Resist top coat composition and patterning process - The present invention relates to a resist top coat composition and a patterning process adopting such a material, which resist top coat composition is provided for forming a top coat on a photoresist film so as to protect the photoresist film, in liguid immersion photolithography. The present invention provides a resist top coat composition for forming a top coat on a photoresist film, wherein the resist top coat composition comprises, at least: a polymer I including a repeating unit a represented by the following general formula (1); and a polymer II including repeating unit having a sulfonic acid or an amine salt of a sulfonic acid: | 2009-08-06 |
20090197201 | FLUOROSURFACTANTS - The present invention relates to the use of end groups Y, where Y stands for (formula I), where Rf stands for CF | 2009-08-06 |
20090197202 | PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL - Disclosed is a photosensitive surface printing plate material which is suitable for the exposure to a laser beam having a light emission wavelength ranging from 350 to 450 nm, is highly sensitive, and has excellent storage stability. The material has a substrate and a photosensitive layer provided on the substrate, wherein the photosensitive layer comprise a polymerization initiator (A), a polymerizable compound (B) having an ethylenic double bond, a sensitizing dye (C), and a polymeric binder (D). In the photosensitive layer, the polymerizable compound (B) comprises a product of the reaction among (a) a compound represented by the general formula (1), (b) a diisocyanate compound and (c) a (methacrylate compound having a hydroxyl group in the molecule. General formula (1): HO—(CH | 2009-08-06 |
20090197203 | Photosensitive conductive paste for transferring and photosensitive transfer sheet - A photosensitive conductive paste for transferring including a metal powder, an inorganic material powder, a photosensitive resin and a polymerization initiator, and to be applied onto a surface of a transfer support, comprising an acrylic resin or a rosin-based resin. | 2009-08-06 |
20090197204 | RESIST COMPOSITION FOR IMMERSION EXPOSURE, METHOD OF FORMING RESIST PATTERN USING THE SAME, AND FLUORINE-CONTAINING COMPOUND - A resist composition for immersion exposure, including a base component (A) that exhibits changed solubility in an alkali developing solution under action of acid, an acid generator component (B) that generates acid upon exposure, and a fluorine-containing compound (C) represented by a general formula (c-1) shown below that is decomposable in an alkali developing solution: | 2009-08-06 |
20090197205 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD - A lithographic printing plate precursor includes a support, an image-recording layer and a protective layer in this order, wherein the protective layer contains a stratiform compound and the image-recording layer contains a polymer compound having a phosphonium structure in a side chain. | 2009-08-06 |
20090197206 | METHOD OF MAKING IMAGES USING FRESH PROCESSING SOLUTION - A method for providing lithographic printing plates is achieved by imaging a lithographic printing plate precursor and processing it with fresh (not reused) samples of a processing solution that both develops and protects the resulting lithographic image. The lithographic printing plate precursors can be either negative-working or positive-working. | 2009-08-06 |
20090197207 | Negative laser sensitive lithographic printing plate having specific photosensitive composition - High speed violet or ultraviolet laser sensitive lithographic printing plate comprising on a hydrophilic substrate a specific photosensitive composition is described. The photosensitive layer comprises an alkaline soluble polymeric binder, a multifunctional (meth)acrylate monomer, a free-radical initiator, and a sensitizing dye. The plate is imagewise exposed with a violet or ultraviolet laser at a dosage of less than 300 μJ/cm | 2009-08-06 |
20090197208 | METHOD FOR MANUFACTURING A PERPENDICULAR MAGNETIC WRITE POLE USING AN ELECTRICAL LAPPING GUIDE FOR TIGHT WRITE POLE FLARE POINT CONTROL - A method for manufacturing a magnetic write head for perpendicular magnetic recording. The method provides for accurate definition of a device feature such as a write pole flare point. A functional lapping guide is formed to determine when a lapping operation should be terminated to define an air bearing surface of a slider. In order to provide accurate compensation for manufacturing variations in the functional lapping guide, a dummy lapping guide is provided. An amount of variation of a front edge of the dummy lapping guide, which is defined by the same process step as a writer pole flare point, can be calculated by measuring the width (stripe height) of the dummy lapping guide based on its electrical resistance. Since the back edges of the dummy lapping guide and functional lapping guide are defined by the same manufacturing steps, the back edge of the functional lapping guide can then be determined, and used for accurately control of the writer flare point through their correlation established from the dummy lapping guide. | 2009-08-06 |
20090197209 | LITHOGRAPHICALLY PATTERNED NANOWIRE ELECTRODEPOSITION - Lithographically patterned nanowire electrodeposition (LPNE) combines attributes of photolithography with the versatility of bottom-up electrochemical synthesis. Photolithography is employed to define the position of a sacrificial nanoband electrode, preferably formed from a metal such as nickel, copper, silver, gold or the like, which is stripped using electrooxidation or a chemical etchant to advantageously recess the nanoband electrode between a substrate surface and the photoresist to form a trench defined by the substrate surface, the photoresist and the nanoband electrode. The trench acts as a “nanoform” to form an incipient nanowire during its electrodeposition. The width of the nanowire is determined by the electrodeposition duration while its height is determined by the height of the nanoband electrode. | 2009-08-06 |
20090197210 | Method for preparing photonic crystal slab waveguides - A method for preparing a photonic crystal slab waveguides is disclosed, wherein the photonic crystal slab waveguides are prepared by combining near-field phase-shifting contact lithography (NFPSCL) with interference lithography (IL). Conventional methods used for preparing the photonic crystal slab waveguides, such as electron beam lithography or direct laser writing, are time consuming. In contrast, the present method allows rapid production of many photonic crystal slab waveguides over a large area composed of microstructures. | 2009-08-06 |
20090197211 | LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - Liquid is supplied to a space between the projection system of a lithographic apparatus and a substrate. A flow of gas towards a vacuum inlet prevents the humid gas from escaping to other parts of the lithographic apparatus. This may help to protect intricate parts of the lithographic apparatus from being damaged by the presence of humid gas. | 2009-08-06 |
20090197212 | Premix Burner Control System and Method - A fan modulated premix burner control system includes a regulating control valve for regulating the pressure of gas fed to a premix chamber. The pressure of the gas is based on the pressure of air also fed into the chamber to produce a constant air/fuel ratio. The system also includes an air restrictor for reducing the pressure of the air to permit operation of the burner at low fan speeds. | 2009-08-06 |
20090197213 | Flint wheel lighter with a safety device - A flint wheel lighter with a safety device, comprises a casing, a fuel container disposed in the casing, a vent assembly, an ignition assembly, and a windproof hood above the fuel container, the ignition assembly is arranged on the side opposite to the windproof hood. Said ignition assembly comprises a press plate, a flint, and a flint wheel. A bent safety rod rotatable with the flint wheel is disposed on the side surface of said flint wheel, with both ends of two sections of said bent safety rods protruding out of the rim of the flint wheel. In a safe mode, the end of one section butts against the inner surface of the top cover of the windproof hood, and the end of the other section lies over the flint wheel. The flint wheel lighter with safety rod provided by the present invention can effectively control the operation of the flint wheel by the safety rod, so as to prevent fire disasters and accidents caused by children playing with the flint wheel. | 2009-08-06 |
20090197214 | Air assisted simplex fuel nozzle - Disclosed is an air-assisted simplex spray nozzle assembly for a fuel burner that includes, inter alia, a nozzle body that has opposed upstream and downstream ends, wherein the downstream end of the nozzle body defines a fuel outlet, an adapter member that is engaged with the upstream end of the nozzle body and defines concentrically positioned air and fuel inlets for the nozzle assembly and an air cap that is positioned over the downstream end of the nozzle body. The nozzle assembly further includes a fuel circuit and a first air circuit. The fuel circuit directs fuel from a fuel pump toward the fuel outlet of the nozzle body. The fuel circuit extends from the fuel inlet of the adapter member through the nozzle body to the fuel outlet. The first air circuit directs assist air towards the fuel exiting from the fuel outlet. The first air circuit extends from the air inlet of the adapter member, through a gap defined between the air cap and the nozzle body and merges with the fuel emitted from the fuel outlet of the nozzle body. In certain embodiments, the assist air is provided to the first air circuit by an auxiliary pump. | 2009-08-06 |
20090197215 | HEATING OBJECTS ON A LINE-PRODUCTION OVEN - A device for heating objects and a method that has recourse to the device, particularly for heating and/or bending one or more glass panes positioned one on top of the other, covering each other. The device includes a furnace line, plural supports, particularly transport molds that transport and/or bend the objects, the objects being placed on the supports positioned on transport carriages, a drive device that progresses the transport carriages through the furnace line and plural heating elements provided above the objects in the furnace line. In the device the heating elements are positioned on the whole above the entire furnace line and the heating elements can be operated and regulated so as to form heating zones suited to dimensions of the objects. | 2009-08-06 |
20090197216 | SELF-ADJUSTING ORTHODONTIC MODULE - An improved force module is used in orthodontic applications for treating patients with overbite or other dental problems. The improved force module may act as a force limiter to limit movement of a pushrod attached to either an archwire or bow and thereby limit a force generated by a spring attached to the pushrod. The improved force module is designed for use in an orthodontic system which self-adjusts, thus eliminating the need for routine adjustment. Also, the improved force module maintains its shape and strength for several months, may be made from a shape memory polymer, and may contain an embedded reinforcing wire or fiber. | 2009-08-06 |
20090197217 | Robot and method for bending orthodontic archwires and other medical devices - A robotic bending apparatus for bending archwires and other types of elongate, bendable medical devices into a desired configuration includes a first gripping tool and a moveable gripping tool. The first gripping tool can be either fixed with respect to a base or table for the robot or positioned at the end of robot am. The moveable gripping tool is mounted to the end of a moveable robot arm having a proximal portion also mounted to the base. The robot preferably comprises a six axis bending robot, in which the distal end of the moveable arm can move relative to the fixed gripping tool about three translational axes and three rotational axes. The gripping tools preferably incorporate force sensors which are used to determine overbends needed to get the desired final shape of the archwire. The robot may also include a resistive heating system in which current flows through the wire while the wire is held in a bent condition to heat the wire and thereby retain the bent shape of the wire. A magazine for holding a plurality of straight archwires needing to be bent and a conveyor system for receiving the wires after the bending process is complete are also described. The robot bending system is able to form archwires with any required second and third order bends quickly and with high precision. As such, it is highly suitable for use in a precision appliance-manufacturing center manufacturing a large number of archwires (or other medical devices or appliances) for a distributed base of clinics. | 2009-08-06 |
20090197218 | UNIVERSAL TRANSITIONAL ABUTMENT - A universal transitional abutment for immediate placement during the first and/or second stages of the dental implant surgery is presented. The transitional dental abutment can approximate the natural appearance of a patient's own tooth. The transitional dental abutment can bypass the traditional anti-rotational component common to most dental implant systems by directly screwing the transitional dental abutment onto a dental implant. In another embodiment, the abutment can be a universal anterior transitional abutment. The anterior transitional dental abutment can comprise a ball and a crown. The ball can be affixed to the dental implant and the crown snaps onto the ball. The transitional dental abutment can be universally used on most dental implants regardless of manufacturer by simply changing the fastener of the transitional dental abutment. The universal transitional abutments can be permanent. Additionally, the universal transitional abutments can be readily available and cost effective to the dental professional. | 2009-08-06 |
20090197219 | SYSTEM FOR A DENTAL IMPLANT SURGICAL GUIDE - The invention concerns guided dental implant surgery involving the preparation of a model with balls indicatine the emergent point of each implant, the preparation of a radiological plate starting from the model and equipped with a radiopaque ball placed in the cast corresponding to each ball of said model, the application of a reference fork for the radiological claque for the carrying out of a CAT scan, the elaboration of the CAT scan data with reference to the emergent point of the implant and successive preparation of a surgical guide with fixing of a directional sleeve on the plaque starting from the emergent point. | 2009-08-06 |
20090197220 | ORAL CLEANING DEVICE AND METHOD OF USE - An oral cleaning device is described. The oral cleaning device includes a brush head, a stem, a suction adapter, and a supply reservoir. The brush head includes a cleaning surface and defines an internal cavity. The stem is coupled to the brush head. The stem includes a fluid channel for bi-directional fluid flow to dispense fluid out of the brush head and to suction fluid into the brush head. The suction adapter is to the stem. The suction adapter couples a suction device to the stem for providing a suction flow within the stem in response to control by a user. The supply reservoir includes an integrated supply adapter to couple the supply reservoir to the suction adapter. The supply reservoir contains a water-based cleaning solution with less than a prescription amount of a cleaning agent. | 2009-08-06 |
20090197221 | DENTAL BONDING COMPOSITIONS AND METHODS USEFUL IN INHIBITION OF MICROLEAKAGE IN RESIN-BONDED DENTIN - Provided are methods and compositions relating to a dental bonding composition useful in bonding a dental resin composite. | 2009-08-06 |
20090197222 | Ball rolling unit - A ball rolling unit for fun to initiate vision and hand coordination for pre-school children includes multiple canopies, a section of course extending downward at a certain inclination being sewn to each canopy; an inner peripheral of each course and its corresponding sides being sewn with hooks and loops of a Velcro to open or close each course; and a ball rolling upon the ball rolling unit for pre-school children standing around the ball rolling unit to roll the ball thereon by holding an edge of the ball rolling unit to pull it up and down for learning to focus on movement of an object and agile reaction of their hands in various forms of the game with each channel opened, closed, or formed into a pocket. | 2009-08-06 |
20090197223 | Map in azimuthal equidistant hemispheric projection with reduced distortion - According to one embodiment, world maps in the Azimuthal Equidistant (AE) Hemispheric projection are formed by depicting the main hemisphere of a globe in full and the opposing hemisphere in the form of two semi-hemispheres contiguous two spaced side portions of the main hemisphere. Any city (or location) of interest in the world can be highlighted as the center point of the main hemisphere. Each of these two semi-hemispheres is movable along the circumference of the main hemisphere so that a straight line can be drawn from the center point of the main hemisphere to any other point on the two semi-hemispheres via corresponding tangent points. This straight line is a part of a great circle and will show correct distance and direction from the center point to the other point. A transparent ruler, a set of gears, a compass rose and others may be attached to this map for quicker and easier acquisition of correct distance and direction. Differing from the regular AE projection, this AE Hemispheric projection has less distortion and more realistic shapes of the continents, even at remote areas, and also shows the antipodal point explicitly as a point. | 2009-08-06 |
20090197224 | Language Learning Apparatus, Language Learning Aiding Method, Program, and Recording Medium - There is provided a language learning apparatus, which includes an inputting portion to which a voice signal is input, a time stretching portion which compresses or expands the voice signal in a time axis direction such that a phonation period of a voice indicated by the voice signal input into the inputting portion is matched with a phonation period of a model voice, a specifying portion which compares the voice signal which is compressed or expanded by the time stretching portion with a voice signal indicating the model voice to specify a different part between the both voice signals, a signal processing portion which applies a signal processing of emphasizing the different part specified by the specifying portion to one of the voice signal input into the inputting portion and the voice signal indicating the model voice, and an outputting portion which outputs a voice signal to which the signal processing is applied by the signal processing portion. | 2009-08-06 |
20090197225 | READING LEVEL ASSESSMENT METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR HIGH-STAKES TESTING APPLICATIONS - A computer-implemented method, system, and computer program product for automatically assessing text difficulty. Text reading difficulty predictions are expressed on a scale that is aligned with published reading standards. Two distinct difficulty models are provided for informational and literary texts. A principal components analysis implemented on a large collection of texts is used to develop independent variables accounting for strong intercorrelations exhibited by many important linguistic features. Multiple dimensions of text variation are addressed, including new dimensions beyond syntactic complexity and semantic difficulty. Feedback about text difficulty is provided in a hierarchically structured format designed to support successful text adaptation efforts. The invention ensures that resulting text difficulty estimates are unbiased with respect to genre, are highly correlated with estimates provided by human experts, and are based on a more realistic model of the aspects of text variation that contribute to observed difficulty variation. | 2009-08-06 |
20090197226 | AGE AND THE HUMAN ABILITY TO DECODE WORDS - Embodiments relate to a method, a system and a computer readable medium having instructions for determining a reading fluency starting age comprising testing a population of different ages on an alphabetical test comprising reading a sentence, ranking a reading fluency score on the alphabetical test versus ages of the population, and determining the reading fluency starting age as an age at which the reading fluency score on the alphabetical test versus ages of the population shows a maximum. | 2009-08-06 |
20090197227 | RELATIONSHIP PERFORMANCE SYSTEM AND METHOD - An apparatus for negotiating a work role relationship between two participants, comprising a Dialog and Agreement Board with multiple in-dialog areas where participants place one or more cards representing elements or parts of the work role relationship or personal characteristics related to the work role, and with a commitment area upon which cards can be taken from the in-dialog areas and placed to represent agreed-upon commitments by the participants. An agreement between the participants may be documented manually or automatically, in whole or in part. Components marked with bar codes can be read for entry into a computer program for documenting agreements. | 2009-08-06 |
20090197228 | DATA MANAGEMENT SYSTEMS FOR COLLISION REPAIR COACHING - A system for on-site collection of evaluation data at a vehicle repair installation site is disclosed. Generally the system includes a computing tool connected to a database, a workflow operations guiding module that runs on the computing tool, an evaluation module, a comparison module, a data-mining module, a certification module, a legal compliance module, and a repair procedure compliance module. As a vehicle is repaired, the workflow operations guiding module prompts a coach with questions. The evaluation module performs a quantitative analysis of the answers provided by the coach and the comparison module compares the result of the quantitative analysis against aggregated or averaged information. The certification module compares information from the comparison module against predetermined certification criteria and the data mining module identifies correlations, trends or patterns in collected data by the system. | 2009-08-06 |
20090197229 | HAZARD SUPPRESSION TRAINING SIMULATOR AND METHOD OF TRAINING - A hazard-suppression training simulator for training, for example, first responders, is provided. The simulator includes a housing; at least one source of sensation (for example, a visual or an audio sensation) representing a hazardous condition, for example, a fire; at least one sensor adapted to detect a simulated or an actual hazardous condition suppressant; and a controller adapted to vary the sensation in response to the simulated or the actual suppressant detected by the at least one sensor. The simulator may also include one or more “props” to better simulate an actual hazardous conditions, for example, a trash can or a stove pot that is on fire. The simulated suppressant may be provided by a simulated fire extinguisher, for example, a simulated extinguisher emitting an electromagnetic or sonic signal representing a fire suppressant. A hazard-suppression training method employing this simulator is also disclosed. | 2009-08-06 |
20090197230 | Method of managing swimming pool activities - A method of managing the activities of adolescents attending a swimming pool facility consisting of identifying nonswimmer adolescents attending the facility, requiring such adolescents to take and pass a swimming test, issuing attire signifying passing such test, requiring such adolescents to wear such attire when entering the pool and barring adolescents failing to wear such attire from entering the pool unless accompanied by an adult guardian. | 2009-08-06 |
20090197231 | Toilet training using absorbent article packaging - Presented is packaging for supplying disposable personal care products to a caregiver and for enhancing toilet training of a child, the packaging including a storage bin having a storage bin bottom and a reclosable cover and defining an interior space; a plurality of disposable personal care products disposed in the interior space; and an informational item adapted to teach the caregiver to use the storage bin to enhance toilet training. Also presented is a method for toilet training a subject, the method including providing a storage bin having a storage bin bottom and a reclosable cover and defining an interior space, wherein a plurality of disposable personal care products disposed in the interior space; and instructing a caregiver to incorporate use of the storage bin into toilet training. | 2009-08-06 |
20090197232 | MATCHING LEARNING OBJECTS WITH A USER PROFILE USING TOP-LEVEL CONCEPT COMPLEXITY - In a method and system for matching learning objects with a user profile, a top-level concept structure, including a keyword hierarchy for each of one or more top-level concepts, can be used to determine the complexity of a learning object. The learning object can include one or more learning object keywords related to one or more top-level concepts contained in the top-level concept structure. The learning object keywords can be assigned a complexity score based upon their location within the keyword hierarchy, and the complexity scores for all of the learning object keywords relating to a top-level concept can be aggregated to generate a learning object top-level concept complexity score. The learning object top-level concept complexity score can be compared with a user's experience rating for that top-level concept and be used to select an appropriate learning object. | 2009-08-06 |
20090197233 | Method and System for Test Administration and Management - Methods and systems are disclosed for test administration and management. A server or server system presents an interface to a client web browser over a network. A user of the client web browser selects a test taker, a test, and a destination identifier. The server or server system may then present the test to the test taker in a call to the destination identifier. After completion of the test, the server or server system may then score the test and display the score of the test in the interface. The interface may also allow the user to play back a recording of a completed test. The interface may support multiple test takers or multiple tests. | 2009-08-06 |
20090197234 | SYSTEM AND METHOD FOR A VIRTUAL SCHOOL - The present invention is directed at a software system for use in an online educational environment. In one embodiment, a software system combines and allows communication between a student management system, a learning management system, and various other portals are interconnected and communicate with one another to allow for an completely integrated online educational institution that allows patents, students, and educators to plan and monitor a student's progress. | 2009-08-06 |
20090197235 | Instruction System and Method - A system and method for computer-aided learning that provides for selecting question information from a structured data source and presenting a question to a networked user at irregular or otherwise predetermined time intervals. Described also is measuring the length of time required for the user to respond to the question before presenting the user additional question information to the user, providing user generated text information associated with the question and presenting links to an online community associated with the question. | 2009-08-06 |
20090197236 | IMPLEMENTING USER-GENERATED FEEDBACK SYSTEM IN CONNECTION WITH PRESENTED CONTENT - Users are enabled to provide structured feedback in connection with interactive presentations by responding to a plurality of predefined questions in connection with a plurality of author predefined points. As each question is presented, the user responds and is then presented with a plurality of supporting statements. The user can either selectively access statement details for one of the supporting statements or accept the statements. A plurality of peer-user responses are presented for each of the questions and the user selects one or more of the peer-user responses as corresponding to the user's response. The responses and selections made by users are collected as user feedback data. A scoring system presents relative scores for the responses by the peer users based on the selections, thereby generating feedback useful to content authors in editing and updating their presentations. This approach for collecting user feedback data is also applicable to other applications. | 2009-08-06 |
20090197237 | SYSTEM AND METHODS FOR SEQUENCING LEARNING OBJECTS BASED UPON QUERY AND USER RELEVANCY - A system for generating a sequence of learning objects comprising an e-Learning course is provided. The system can include one or more processors and a memory unit for electronically storing data comprising a plurality of learning objects. The system further can include a sequence builder configured to execute on the at least one processor. The sequence builder, more particularly, can be configured to generate a sequence comprising at least a portion of the plurality of learning objects based upon a measurable user relevancy and/or a measurable query relevancy of each learning object contained in the sequence. | 2009-08-06 |
20090197238 | EDUCATIONAL CONTENT PRESENTATION SYSTEM - An educational content presentation system and a file format for facilitating learning in that presentation system are provided. The presentation system receives an archival file, such as a ZIP file, that comprises a manifest, one or more activities, and one or more libraries. The manifest associates activities with educational content in the one or more libraries. Some or all the educational content in the library can be encrypted to facilitate digital rights management of the content or provide security in learner assessment activities. Activities can then be executed, such as by a Common Language runtime or Java virtual machine, which present the educational content in the associated libraries to facilitate student learning. | 2009-08-06 |
20090197239 | Ching-Min Huang Education System - The proposed new education system, C.-M. Huang Education System, is according to the “Education Theory of Ching-Min Huang—General Education and Specialized Learning”. | 2009-08-06 |
20090197240 | SYSTEMS AND METHODS FOR EX VIVO LUNG CARE - Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas. | 2009-08-06 |
20090197241 | SYSTEMS AND METHODS FOR EX VIVO LUNG CARE - Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas. | 2009-08-06 |
20090197242 | Lipidomic Approaches to Determining Drug Response Phenotypes in Cardiovascular Disease - The present invention concerns the application of lipidomics to statin treatment for disorders such as cardiovascular disorders. Hence, the invention provides, among other things, a method of correlating a lipid profile with a positive or negative response to a statin treatment regimen by obtaining a lipid profile of a sample from a mammalian subject following commencement of the treatment regimen; and correlating the lipid profile in the sample with a positive or negative response to the treatment regimen. The invention further provides a method of correlating a lipid profile with a positive or negative response to a statin treatment regimen by obtaining a lipid profile of a sample from a mammalian subject before commencement of the treatment regimen; and correlating the lipid profile in the sample with a positive or negative response to the treatment regimen. | 2009-08-06 |
20090197243 | Method and composition for rapid viability testing of cells - The present invention relates to a method for rapidly monitoring a stress response of a cell to a stressor and determining the magnitude of the stress response; a method for rapidly detecting the presence or absence of a cell by monitoring a stress response of the cell if said cell is present, or the absence of the stress response if said cell is absent or dead; and a method for determining a predictive outcome for the susceptibility of a cell to a selected concentration of a bio-active agent or environmental factor and a level of stress of the cell at the selected concentration of the bio-active agent. Also disclosed are kits for carrying out the methodology according to an embodiment of the invention. | 2009-08-06 |
20090197244 | Method for typing and detecting HBV - The present invention relates to a method for detection and/or genetic analysis of HBV in a biological sample, comprising hybridizing the polynucleic acids of the sample with a combination of at least two nucleotide probes, with said combination hybridizing specifically to a mutant target sequence chosen from the HBV RT pol gene region and/or to a mutant target sequence chosen from the HBV preCore region and/or to a mutant target sequence chosen from the HBsAg region of HBV and/or to a HBV genotype-specific target sequence, with said target sequences being chosen from FIG. | 2009-08-06 |
20090197245 | Rapid detection of dengue virus - One example of a solution provided here comprises providing a single-stranded oligonucleotide, the oligonucleotide being complementary to a portion of SEQ ID NO:1, and contacting the oligonucleotide with a nucleic acid comprising the sequence of SEQ ID NO:1, under conditions that permit hybridization of the oligonucleotide with the nucleic acid. Another example comprises providing a single-stranded oligonucleotide comprising the sequence of SEQ ID NO:4, and contacting the oligonucleotide with a nucleic acid comprising the sequence of SEQ ID NO:1, under conditions that permit hybridization of the oligonucleotide with the nucleic acid. | 2009-08-06 |
20090197246 | Haplotypes and polymorphisms linked to human thiopurine s-methyltransferase deficiencies - Haplotypes and polymorphisms of thiopurine S-methyltransferase (TPMT) are described that are linked to TPMT deficiencies which can cause potentially fatal toxicity when patients are treated with thiopurines like mercaptopurine, azathioprine, or thioguanine. The mutant alleles as well as PCR fragments, kits and methods for assaying the TPMT genotype of individual patients are disclosed. Furthermore, algorithms are disclosed that combine the genotypes of a set of single nucleotide polymorphisms to haplotypes that give a distinct information about the TPMT phenotype. | 2009-08-06 |
20090197247 | Composition for increasing microorganism wall permeability and method for detecting said microorganisms on a membrane - The present invention relates to a composition for permeabilizing microorganism walls, comprising the combination of polyethyleneimine (PEI) with at least one alcohol, and also to a method using said composition for counting and detecting in a targeted manner the microorganisms on a membrane. The invention also relates to a kit and to probes that are suitable for carrying out said method. | 2009-08-06 |
20090197248 | VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS - The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention. | 2009-08-06 |
20090197249 | COMPOSITIONS AND METHODS FOR DIAGNOSING COLON DISORDERS - The present invention relates to methods and compositions for diagnosing, monitoring, prognosticating, analyzing, etc., polymicrobial diseases. The present invention also relates to the microbial community present in the digestive tract and lumen in normal subjects, and subjects with digestive tract diseases, especially diseases of the colon, such as inflammatory bowel disease, including ulcerative colitis, Crohn's syndrome, and pouchitis. The present invention especially relates to compositions and methods for diagnosing and prognosticating the mentioned diseases and conditions, e.g., to determine the presence of the disease in a subject, to determine a therapeutic regimen, to determine a therapeutic regimen, to determine the onset of active disease, to determine the predisposition to the disease, etc. | 2009-08-06 |
20090197250 | METHODS AND NUCLEIC ACIDS FOR THE ANALYSIS OF GENE EXPRESSION ASSOCIATED WITH THE PROGNOSIS OF PROSTATE CELL PROLIFERATIVE DISORDERS - Particular aspects provide novel methods and compositions (e.g., nucleic acids, kits, etc.) having substantial utility for providing a prognosis of prostate cell proliferative disorders. In particular aspects, this is achieved by the analysis of the expression status of a panel of genes, or subsets thereof. | 2009-08-06 |
20090197251 | Process for marking products with nucleic acids for proving the identity and origin of the products - The invention relates generally to product identification and, more particularly, to processes for marking products with nucleic acids to establish the identity and origin of the products, to track them and to determine their quantity in the event of blending or dilution with other products. The invention also relates to the use of nucleic acids which code characters and character sequences for marking products and to products containing nucleic acids which code characters and character sequences. | 2009-08-06 |
20090197252 | Detection of Mutations - The present invention relates to a polypeptide which is flavin-containing monooxygenase 3 (FMO3), wherein said FMO3 is a polypeptide comprising at least a sequence having at least 85% identity with the polypeptide sequence SEQ ID NO: 15, in particular to a polypeptide which is a functionally altered mutant of flavin-containing mono oxygenase 3 (FMO3) leading to a buildup of trimethylamine in an animal. Further, the invention relates to nucleic acid sequences encoding said polypeptide, and to the complements of such nucleic acid sequences. Such nucleic acid sequences and fragments thereof may be useful e.g. as primers. The invention further relates to various methods for determining the presence in e.g. a nucleic acid sample of a nucleic acid sequence encoding a mutated FMO3 polypeptide. | 2009-08-06 |
20090197253 | HIGH FREQUENCY OF NEUREXIN 1BETA SIGNAL PEPTIDE STRUCTURAL VARIANTS IN PATIENTS WITH AUTISM - The three β-neurexins have similar roles in synaptogenesis and interact with the neuroligins. Mutations located within the gene encoding neurexin 1 have been identified as molecular markers associated with autism and autism-related disorders. The estimated attributable risk is 2%. The invention provides methods of diagnosing or predicting susceptibility to developing autism in an individual by determining the presence or absence of one or more genetic variant of a neurexin 1 gene in an individual. | 2009-08-06 |
20090197254 | VARIANT SCORPION PRIMERS FOR NUCLEIC ACID AMPLIFICATION AND DETECTION - Disclosed herein are methods of detecting target nucleic acids. In particular, methods for avoiding loss of the fluorescent label form an amplicon that is generated using a Scorpion primer and a polymerase with 5′ exonuclease activity. The methods use a Scorpion primer which comprises a fluorophore, a quencher, and in 5′ to 3′ order, a probe region, a linker region and a primer region, wherein the quencher is located at or near the 5′ end, and, wherein the primer is complementary to the target nucleic acid and the probe region hybridizes to a complementary sequence in an extension product of the primer. The methods provide for detection of target nucleic acids in simplex or multiplex formats. | 2009-08-06 |
20090197255 | Determining a predisposition to cancer - The present invention relates to methods and kits for determining a predisposition for developing cancer, e.g., prostate and/or breast cancer, due to a germline mutation of a NBS1 gene. The present invention also relates to surveillance protocols for developing cancer, e.g., prostate and/or breast cancer, due to germline mutation of a NBS1 gene. | 2009-08-06 |
20090197256 | Use of a fibroblast growth factor-binding protein for the treatment and diagnosis of diabetic wound healing problems - The present invention relates to the use of fibroblast growth factor-binding protein (FGF-BP) polypeptides, and functional variants of these polypeptides, respectively, or of nucleic acids encoding these polypeptides or variants, or of functional variants of these nucleic acids, and/or of a cell which is expressing an FGF-BP polypeptide or functional variants thereof, for treating, diagnosing and/or preventing wound healing disturbances which are characterized by a reduced quantity of FGF-BP, in particular diabetes-associated wounds, and also to the use of at least one FGF-BP polypeptide as depicted in SEQ ID No. 1 and SEQ ID No. 3 and/or of at least one FGF-BP-encoding nucleic acid as depicted in SEQ ID No. 2 and SEQ ID No. 4 and/or of antibodies or antibody fragments which are directed against an FGF-BP polypeptide which can be used in accordance with the invention, or functional variants thereof, and/or of a cell which is expressing an FGF-BP polypeptide or functional variants thereof, for identifying pharmacologically active substances which increase the activity of expression of FGF-BP. | 2009-08-06 |
20090197257 | PAIRED-END READS IN SEQUENCING BY SYNTHESIS - The disclosure provides methods of generating paired reads in sequencing-by-synthesis process, particularly, in systems with relatively short read lengths (e.g., 15-35 bases), such as for example, in single molecule sequencing by synthesis. Several implementations of the methods are provided. Of particular advantage are the methods that permit re-sequencing of the template, which yields lower error rates. The invention further provides methods of using paired reads, for example, for positioning them over repeats or for assembly into large sequences, including whole genome assembly. | 2009-08-06 |
20090197258 | PRIMARY RAT HEPATOCYTE TOXICITY MODELING - The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cells exposed to a known toxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes. | 2009-08-06 |
20090197259 | Gene signature for diagnosis and prognosis of breast cancer and ovarian cancer - A first embodiment is a breast cancer prognosticator comprising a detection mechanism consisting a 15-gene signature. In addition there are embodiments comprised of 23-gene signatures and 28-gene signatures. The 28-gene signature may also be used for the prognosis of ovarian cancer. A second embodiment is a method to determine metastatic potential, relapse potential, or both in breast cancer patients comprising collecting a sample from an individual, removing marker-derived polynucleotide from said sample, using a detection mechanism to search for positive matches of said polynucleotides and either the 15, 23, or 28-gene signatures, and developing a quantitative expression profile. Utilizing risk analysis the individual can be placed into one of two or more groups predicting risk and/or clincopathogic variables. Another embodiment is a method to determine relapse free potential in breast cancer patients comprising collecting a sample from an individual, removing marker-derived polynucleotide from said sample, using a detection mechanism to search for positive matches of said polynucleotides and a 24-gene signature, and developing a quantitative expression profile. | 2009-08-06 |
20090197260 | METHOD FOR PREDICTING THE VIABILITY AND VITALITY OF BACTERIA USABLE IN STRESSING ENVIRONMENT - A method for predicting viability, vitality and stability of bacteria, which are usable in stressing environments, produced in the form of bacterial preparations and packed in a frozen or lyophilised form, includes pre-suspending the bacterial preparations in non-stressing aqueous nutrient medium, carrying out a molecular measurement of at least one type of marker gene whose stress state is representative for each considered bacterium species, measuring intracellular pH and in comparing the measured values with reference and/or reference standard values. The use of the inventive method for controlling quality of stress adaptation of bacterial preparations and for selecting such preparations is also disclosed. The invention in particular relates to malolactic and probiotic ferments. | 2009-08-06 |