32nd week of 2014 patent applcation highlights part 43 |
Patent application number | Title | Published |
20140219878 | MIXED PHASE OXIDE CATALYSTS - An emission control catalyst for treating an engine exhaust includes non-precious metal group (“NPGM”) mixed phase oxide catalyst having a mullite phase containing optionally in close contact with other metal oxides. The mixed phase catalyst may be included in one or more layers or zones of a multi-layered or multi-zoned emission control catalyst and optionally in combination with precious metal catalysts such as Pt, Pd and Au. | 2014-08-07 |
20140219879 | Copper CHA Zeolite Catalysts - Zeolite catalysts and systems and methods for preparing and using zeolite catalysts having the CHA crystal structure are disclosed. The catalysts can be used to remove nitrogen oxides from a gaseous medium across a broad temperature range and exhibit hydrothermal stable at high reaction temperatures. The zeolite catalysts include a zeolite carrier having a silica to alumina ratio from about 15:1 to about 256:1 and a copper to alumina ratio from about 0.25:1 to about 1:1. | 2014-08-07 |
20140219880 | Multi-Component Filters For Emissions Control - Catalytic articles, systems and methods for treating exhaust gas streams are described. A catalytic article comprising a wall flow filter having gas permeable walls, a hydrolysis catalyst, an optional soot oxidation catalyst, a selective catalytic reduction catalyst permeating the walls, an ammonia oxidation catalyst and an oxidation catalyst to oxidize CO and hydrocarbons is described. Methods of treating exhaust gas streams comprising soot, an ammonia precursor such as urea, ammonia, NO | 2014-08-07 |
20140219881 | BIOOPTICAL AND BIOFUNCTIONAL PROPERTIES, APPLICATIONS AND METHODS OF POLYLACTIC ACID FILMS - High surface energy materials with low refractive index and UV transparency wherein multilayers of similar or dissimilar materials are thermally fused together to form various functional optical requirements are provided. In some embodiments, a photocatalytic biopolymer structure comprising of a UV transparent biopolymer in integrating fused nanophotocatalytic minerals such as Tio2 used for various applications is provided. Many embodiments are based on the integration of nanophotocatalytic minerals fused to a biopolymer structure in which the biopolymer structure is UV transparent (UVT) and allows UV light to be transmitted through the biopolymer structure activating the nanophotocatalytic fused layer. | 2014-08-07 |
20140219882 | AN OZONE GENERATOR - An ozone generator comprising an ultraviolet light source and a housing defining a space around the ultraviolet light source. The housing is configured to direct a gas comprising oxygen through an ozone generation zone in which the gas containing oxygen is exposed to ultraviolet light. The housing further at least partially define a non-reaction zone wherein any gas or fluid is substantially stagnant and wherein the ultraviolet light source emit ultraviolet light through the non-reaction zone. | 2014-08-07 |
20140219883 | OZONE GENERATION SYSTEM - In the present invention, a gas flow rate adjustment apparatus that outputs a raw material gas to an ozone generation apparatus is provided. The gas flow rate adjustment apparatus includes a plurality of flow rate adjustment parts, and outputs a second mixed gas serving as the raw material gas to the ozone generation apparatus. The second mixed gas includes an oxygen gas outputted from a first oxygen flow rate adjustment part and a first mixed gas outputted from a mixed gas flow rate adjustment part. The raw material gas generated by the gas flow rate adjustment apparatus, which includes an oxygen gas and a nitrogen gas, contains the nitrogen gas added to the oxygen gas with the rate of addition being in a range of more than 0 PPM and not more than 100 PPM. | 2014-08-07 |
20140219884 | HIGH EMISSIVITY AND HIGH TEMPERATURE DIFFUSION BARRIER COATINGS FOR AN OXYGEN TRANSPORT MEMBRANE ASSEMBLY - An oxygen transport membrane assembly having a coating or overlay system is provided. The overlay or coating system is disposed on the one or more surfaces of the metal containing components within the oxygen transport membrane assembly and comprises a plurality of protective layers providing oxidation resistance, chromium diffusion barrier and high emissivity. The disclosed overlay or coating system may include at least one layer of an aluminum oxide or magnesium-aluminum oxide to provide an effective oxidation resistance and/or chromium diffusion barrier. In addition, the overlay or coating system includes a high emissivity layer such as a high porosity ceramic-oxide layer or an aluminum-phosphate layer including a plurality of carbon encapsulated within the aluminum-phosphate matrix. | 2014-08-07 |
20140219885 | SYSTEMS AND METHODS FOR FAST TEST STRIP INTENSITY RECOGNITION - Techniques for fast and accurate measuring test strip intensities are disclosed herein. A method for measuring a test strip intensity comprising steps of obtaining an image of a sample line in a test strip and a plurality of reference lines, wherein the reference lines have known intensities; determining grayscale values of the sample line and the reference lines from the image; constructing a standard curve based on the grayscale values versus the known intensities of the reference lines; and determining the intensity of the sample line by fitting the grayscale value of the sample line on the standard curve. | 2014-08-07 |
20140219886 | CAPILLARY MICROCUVETTE HAVING DOUBLE LOADING MEANS - The present invention relates to a capillary microcuvette, the microcuvette comprises a body member having two plates and a cavity formed within the body, the cavity being defined by two opposing inner surfaces of the two plates of the body member, a portion of the cavity defining a detection zone, a capillary inlet being provided at one end of the body member that is communicated with the cavity, a sample slot being provided at a portion of the body member in which the capillary inlet is not formed, the sample slot being communicated with the cavity. The present microcuvette improves user convenience by providing dual application means of applying a specimen directly from a fingertip or using a pipette. | 2014-08-07 |
20140219887 | APPARATUS AND METHODS FOR PIPETTING WITH INTERCHANGEABILITY AMONG DIFFERENT PIPETTE TIPS - Pipette tips of different sizes may be coupled to a pipettor without needing to modify the pipettor. The same pipettor may thus be utilized to exchange different pipette tips, which may be done in an automated manner. Pipette tips may be coupled to adaptors that include proximal ends for interfacing with the pipettor and distal ends for interfacing with pipette tips. The proximal ends may all have the same geometry, matched with the same pipettor. The distal ends may have different geometries matched with different pipette tips. A pipettor may be part of a liquid handling apparatus and movable in an automated manner to different deck positions. The pipettor may include a locking mechanism for locking adaptors to the pipettor or locking pipette tips directly to the pipettors, and an ejection mechanism for ejecting pipette tips from corresponding adaptors. | 2014-08-07 |
20140219888 | TUBE AND FLOAT SYSTEM AND METHODS OF USING THE SAME - This disclosure is directed to systems and methods for analyzing target materials of a suspension include a tube and a float. The float may include expandable portions. The system traps a target analyte between the expandable float and the tube and/or to create a seal between the expandable float and the tube to inhibit fluid from flowing past the expandable float in the tube. The expandable portions may radially expand when exposed to an expanding fluid, such that the expanding fluid is not a naturally-occurring constituent of the suspension; or, the expandable portions may radially expand when a force is exerted upon the expandable portion. A tube may include expandable portions that expand towards the float. | 2014-08-07 |
20140219889 | METHOD AND APPARATUS FOR DISPENSING DIAGNOSTIC TEST STRIPS - An apparatus for storing and dispensing a test strip includes a container configured to store a stack of test strips. The container maintains appropriate environmental conditions, such as humidity, for storing the test strips. An engaging member is disposed in the container and is adapted to contact one test strip of the stack of test strips. An actuator actuates the engaging member to dispense the one test strip from the container. Since one test strip is dispensed at a time, the remaining test strips are not handled by the user. Accordingly, the unused test strips remain free of contaminants such as naturally occurring oils on the user's hand. | 2014-08-07 |
20140219890 | Permanently Sealable Non-Reusable Time Capsule, Container Or Vessel - The present invention relates to time capsules, vessels or containers, in particular but not limited to a permanently sealable non-reusable time capsule, vessel or container for storing a biological sample containing DNA for a prolonged period of time. The time capsule comprising a thick-walled vessel or container having a void or chamber with a tapered entry adapted to house glass vials containing the item of interest, a plug having a complementary external tapered configuration corresponding to the tapered entry, the tapered plug and entry having opposed peripheral grooves that are aligned when the plug is positioned in the vessel and a hard setting compound used to seal the plug forms a keyed ring in the opposing grooves to permanently and hermetically seal the plug in the vessel. | 2014-08-07 |
20140219891 | SEPARATION METHOD OF ZIRCONIUM AND HAFNIUM BY SOLVENT EXTRACTION PROCESS - A separation method of zirconium and hafnium is described which includes an extraction process of agitating an undiluted aqueous solution containing zirconium, hafnium, and sulfuric acid with a first stirring solution containing an acidic extractant to produce a first extract solution in which the hafnium is extracted by the acidic extractant; and a recovery process of agitating the first extract solution with a second stirring solution containing a citric acid solution to produce a citric acid solution after extraction in which zirconium is reverse-extracted from the first extract solution to the citric acid solution so as to recover zirconium contained in the first extract solution. The method may reduce the amount of extractant while greatly enhancing the separation effect of zirconium and hafnium, and increase zirconium recovery rate by more than 97% through an additional zirconium recovery process while reducing a hafnium content in zirconium by less than 50 ppm. | 2014-08-07 |
20140219892 | SEPARATION METHOD FOR POTASSIUM FROM AQUEOUS KOH SOLUTIONS - The process described herein demonstrates a more efficient and effective way to remove certain chemicals from industrial waste water. Specifically, the invention set forth demonstrates a method comprised of at least two steps in which up to 96% of potassium can be removed from an aqueous solution comprising potassium hydroxide. | 2014-08-07 |
20140219893 | CYCLOHEXASILANE AND METHOD FOR PRODUCING THE SAME - High purity cyclohexasilane and a method for increasing the purification efficiency thereto are provided. The method for producing cyclohexasilane of the present invention is characterized in that, in distilling crude cyclohexasilane to obtain purified cyclohexasilane, the absolute pressure during distillation is set to 2 kPa or less, and the heating temperature of crude cyclohexasilane is set to 25 to 100° C. The cyclohexasilane of the present invention contains pure cyclohexasilane at a rate of 98% by mass or more and 100% by mass or less. | 2014-08-07 |
20140219894 | DEVICE AND METHOD FOR GAS TREATMENT USING NON-THERMAL PLASMA AND CATALYST MEDIUM - To provide a device and a method for oxidation decomposition treatment of a hazardous gas of a volatile organic compound (VOC) or the like at normal temperature. | 2014-08-07 |
20140219895 | INTEGRATED CHEMICAL LOOPING AIR SEPARATION IN LARGE-SCALE OXY-FUEL PLANTS - An integrated chemical looping air separation unit ( | 2014-08-07 |
20140219896 | HEAT GENERATION SYSTEM FOR DETERMINING A SELECTIVE CATALYTIC REDUCTION DEVICE EFFICIENCY - A control method and system for monitoring a selective catalytic reduction (“SCR”) device of an exhaust gas treatment system is disclosed. The method includes monitoring a plurality of operating conditions related to determining an efficiency of the SCR device and a SCR temperature. The method includes determining if each of the operating conditions are within a respective predetermined range and if the SCR temperature is below an operating temperature range. The method includes activating a hydrocarbon supply based on if each of the operating conditions are within the respective predetermined range and if the SCR temperature is below the operating temperature range. The hydrocarbon supply is located upstream of the SCR device to generate heat if activated. The method includes monitoring the SCR temperature to determine if the SCR device is operating within the operating temperature range. | 2014-08-07 |
20140219897 | METHOD AND APPARATUS FOR ANALYSIS AND SELECTIVE CATALYTIC REDUCTION OF NOX-CONTAINING GAS STREAMS - An apparatus and method for measuring and controlling the NO | 2014-08-07 |
20140219898 | METHOD OF RECOVERING CARBON DIOXIDE AND RECOVERY APPARATUS - A carbon dioxide recovery method and a recovery apparatus are capable of decreasing energy for regenerating an absorbing liquid to reduce operating cost. The apparatus has an absorption column that the absorbing liquid absorbs carbon dioxide of a gas, a regeneration column heating and regenerating the absorbing liquid with discharge of carbon dioxide, and a circulation system circulating the absorbing liquid. The absorbing column has first and second absorbing sections, and gas is supplied to the second absorbing section through the first absorbing section. The regeneration column has a first regeneration section having an external heating implement and a second regeneration section heated by the gas discharged from the first regeneration section. The circulation system has a first circulation path circulating between the first absorption section and the second regeneration section and a second circulation path circulating between the second absorption section and the first regeneration section, separately. | 2014-08-07 |
20140219899 | Methods and Systems for Capturing Carbon Dioxide From Dilute Sources - Methods and systems for capturing carbon dioxide from dilute sources are disclosed. In some embodiments, the methods include the following: (a) directing a first substantially gaseous stream including a first amount of carbon dioxide to a primary scrubber; (b) in the primary scrubber, removing a portion of the first amount of carbon dioxide thereby forming a second substantially gaseous stream including a second amount of carbon dioxide; (c) directing the second substantially gaseous stream to a secondary scrubber; (d) in the secondary scrubber, removing a portion of the second amount of carbon dioxide thereby forming a third substantially gaseous stream; (e) mixing substantially all of the portion of the second amount of carbon dioxide removed in step (d) with the first substantially gaseous stream before it enters the primary scrubber; and (f) repeating steps (a) thru (e). | 2014-08-07 |
20140219900 | PROCESS FOR PREPARING AN OXYHALOGENIDE AND/OR OXIDE OF ACTINIDE(S) AND/OR OF LANTHANIDE(S) FROM A MEDIUM COMPRISING AT LEAST ONE MOLTEN SALT - The invention relates to a process for manufacturing an oxychloride or oxide of actinide(s) and/or of lanthanide(s) from a chloride of actinide(s) and/or of lanthanide(s) present in a medium comprising at least one molten salt of chloride type comprising a step of bringing said chloride of actinide(s) and/or lanthanide(s) present in said medium comprising at least one molten salt of chloride type into contact with a wet inert gas. | 2014-08-07 |
20140219901 | Methods for Associating or Dissociating Guest Materials with a Metal Organic Framework, Systems for Associating or Dissociating Guest Materials Within a Series of Metal Organic Frameworks, Thermal Energy Transfer Assemblies, and Methods for Transferring Thermal Energy - Methods for releasing associated guest materials from a metal organic framework are provided. Methods for associating guest materials with a metal organic framework are also provided. Methods are provided for selectively associating or dissociating guest materials with a metal organic framework. Systems for associating or dissociating guest materials within a series of metal organic frameworks are provided. Thermal energy transfer assemblies are provided. Methods for transferring thermal energy are also provided. | 2014-08-07 |
20140219902 | MECHANOCHEMICAL SYNTHESIS OF HEXAGONAL OsB2 - The presently disclosed and/or claimed inventive concept(s) relates generally to hexagonal osmium boride, OsB | 2014-08-07 |
20140219903 | FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF - The present invention relates to a film composed of a carbon-containing silicon oxide formed by CVD using, as the raw material, an organosilicon compound having a secondary hydrocarbon group directly bonded to at least one silicon atom and having an atomic ratio of 0.5 or less oxygen atom with respect to 1 silicon atom, which is used as a sealing film for a gas barrier equipment and materials, an FPD device, a semiconductor device and the like. | 2014-08-07 |
20140219904 | GEOTHERMAL ENERGIZATION OF A NON-COMBUSTION CHEMICAL REACTOR AND ASSOCIATED SYSTEMS AND METHODS - Systems and methods for heating a non-combustion chemical reactor with thermal energy from a geothermal heat source are described. A working fluid is directed from the geothermal heat source to the chemical reactor to transfer heat. The working fluid can be circulated in a closed system so that it does not contact material at the geothermal heat source, or in an open system that allows the working fluid to intermix with material at the geothermal heat source. When intermixing with material at the geothermal heat source, the working fluid can transport donor substances at the geothermal heat source to the chemical reactor. | 2014-08-07 |
20140219905 | VAPOR DEPOSITION REACTOR AND METHOD FOR FORMING THIN FILM - A vapor deposition reactor and a method for forming a thin film. The vapor deposition reactor includes at least one first injection portion for injecting a reacting material to a recess in a first portion of the vapor deposition reactor. A second portion is connected to the first space and has a recess connected to the recess of the first portion. The recess of the second portion is maintained to have pressure lower than the pressure in the first space. A third portion is connected to the second space, and an exhaust portion is connected to the third space. | 2014-08-07 |
20140219906 | GRAPHENE-NANO PARTICLE COMPOSITE HAVING NANO PARTICLES CRYSTALLIZED THEREIN AT A HIGH DENSITY - The present invention relates to a graphene-nanoparticle composite having a structure in which nanoparticles are crystallized in a carbon-based material, for example, graphene, at a high density, and, more particularly, to a graphene-nanoparticle composite capable of remarkably improving physical properties such as contact characteristics between basal planes of graphene and conductivity, wherein nanoparticles are included as a large amount of 30% by weight or more, based on 100% by weight of graphene, and crystallized nanoparticles have an average particle diameter of 200 nm or more, and a method of preparing the same. | 2014-08-07 |
20140219907 | SINGLE-CRYSTAL DIAMOND AND MANUFACTURING METHOD THEREOF - Single-crystal diamond is composed of carbon in which a concentration of a carbon isotope | 2014-08-07 |
20140219908 | METHODS OF PRODUCING COILED CARBON NANOTUBES - Methods and systems for producing coiled nanotubes. At least one exemplary method of producing coiled carbon nanotubes of the present disclosure comprises the steps of reacting a carbon feedstock and a catalyst within a reaction vessel to produce a reaction product comprising at least about 5% coiled carbon nanotubes, wherein the carbon feedstock comprises either (i) a mixture of a hydrocarbon and water or (ii) an alcohol, and wherein the catalyst comprises at least one Group VIB or VIIIB transition metal. | 2014-08-07 |
20140219909 | METHOD FOR PRODUCING A LIGNIN FIBER - Disclosed is a method of producing a continuous lignin fiber from softwood and/or hardwood alkali lignin. The lignin fiber can be further treated to obtain structural carbon fiber. | 2014-08-07 |
20140219910 | SULPHURIC ACID PRODUCTION WITH RECYCLE OF DESULPHURIZED GAS - The invention relates to a process for oxidation of SO | 2014-08-07 |
20140219911 | DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION - The present invention discloses a class of organometallic catalysts for both hydrogenation and water oxidation. The synthesis and the use of these catalysts for hydrogenation, hydrogen production and water oxidation reactions is also disclosed. | 2014-08-07 |
20140219912 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 2014-08-07 |
20140219913 | Dual Specific Binding Proteins Having a Receptor Sequence - Engineered multispecific binding proteins that bind at least one ligand for a receptor are provided, along with methods of making and uses in the prevention, diagnosis, and/or treatment of disease. | 2014-08-07 |
20140219914 | Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity - The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to EGP-1 (TROP-2), CEACAM5, CEACAM6, CD74, CD19, CD20, CD22, CSAp, HLA-DR, AFP or MUC5ac and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 24 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. | 2014-08-07 |
20140219915 | CRYPTATE COMPOUNDS - Disclosed herein is a method for coupling a first compound having the formula (I) with a second compound that contains a carbonyl group. Also disclosed herein are compounds that can be formed by this method, and uses for such compounds. | 2014-08-07 |
20140219916 | METHOD AND COMPOUND FOR TREATMENT OF CANCER USING PHOSPHOROUS-32 LABELED DNA - This invention provides a combination of a DNA strand/fragment and isotope therapy that is applied to a cancerous tissue to selectively kill cancer cells with minimal negative effects on surrounding non-cancerous cells. Linear DNA fragments with labeled isotope are able to be absorbed by the tumor cells and bind the tumor cell's DNA through recombination, and then the isotope kills the tumor cells. Illustratively, a gene or a DNA fragment is employed as a carrier to deliver the P-32 which can kill cancer cells through radioactive emission. The illustrative embodiment produces the compound/agent containing a DNA fragment and P-32 through use of conventional P-32 labeling techniques such as those employed in molecular biology experiments (for example experiments used to test gene expression and gene amplification potency). The same P-32 labeled DNA can be employed directly for cancer treatment through a novel medical treatment method. Appropriate doses are provided to patients as part of a medical treatment method. | 2014-08-07 |
20140219917 | OLIGOSACCHARIDE CONJUGATES FOR TARGETING BACTERIA AND USES RELATED THERETO - This disclosure relates to conjugates for targeting bacteria and related uses. In certain embodiments, the disclosure relates to methods of transferring a molecule of interest into bacteria comprising mixing bacteria with a non-naturally occurring conjugate under conditions such that the conjugate is transported across the bacterial cell wall. Typically, the conjugate comprises an oligosaccharide and a molecule of interest. In certain embodiments, the molecule of interest may be a tracer or an antibiotic. | 2014-08-07 |
20140219918 | PEPTIDE - The present invention provides a foot-and-mouth diseases virus (FMDV) VP1 capsid protein which comprises an entity of interest (EOI). The EOI sequence may, for example, be an epitope tag, an immunomodulatory molecule or a target molecule. The present invention also provides an FMDV vaccine which comprises such a VP1 capsid protein and its use to prevent FMD. | 2014-08-07 |
20140219919 | IL-11R BINDING PROTEINS AND USES THEREOF - The present disclosure provides proteins comprising antigen binding sites of antibodies that bind to interleukin-11 (IL-11) receptor alpha (IL-11Rα) and uses thereof, e.g., in therapy. | 2014-08-07 |
20140219920 | IMMUNOCYTOKINE COMBINATION THERAPY - Methods and compositions for treating tumours, especially skin tumours, by locally administering single doses of tumour necrosis factor alpha (TNFα) and interleukin-2 (IL2) at the tumour site, where the TNFα and IL2 are delivered as immunoconjugates comprising an antibody targeted to a splice isoform of an extracellular matrix component such as fibronectin. | 2014-08-07 |
20140219921 | IMMUNOMODULATING COMPOSITIONS AND METHODS - The disclosure provides compositions in the form of cells exhibiting the phenotype of a mesenchymal stem cell and uses of such cells in the preparation of medicament and the treatment of an allergic reaction in an asthmatic subject. Also provided are methods of inducing tolerance to an allergen in an asthmatic subject and methods of assessing a non-asthmatic subject for amenability to allergy treatment by administering mesenchymal stem cells. | 2014-08-07 |
20140219922 | Use of scintillator-based nanoparticles for in vivo control of light-sensitive bioactive molecules - The method for remote, non-invasive in vivo control of the activation of light-sensitive bioactive molecules for the purpose of research or therapy is based on delivering to the required site of the body of nanoparticles along with said light-sensitive bioactive molecules. Nanoparticles' core is made from scintillator material that absorbs X-ray and in response emits visible light; they have biocompatible protective coating and surface targeting agents enabling accumulation at the required site(s) within the body. Irradiation of the site with the highly penetrable X-rays causes nanoparticles to emit visible light which will activate light-sensitive bioactive molecule(s) within this site inducing sought therapeutic effect. | 2014-08-07 |
20140219923 | BIODEGRADABLE COMPOSITIONS SUITABLE FOR CONTROLLED RELEASE - A special class of drug-depot forming triblock copolymers which are very suitable for the loading, containment and releasing of sensitive drugs such as proteins from biodegradable, injectable drug depots. How to visualize these depots for various imaging related purposes is described. A composition comprising a tri-block copolymer according to formula 1 B-A-B ( | 2014-08-07 |
20140219924 | MEDICAL TISSUE-MARKER AND MANUFACTURING METHOD FOR THE SAME - The present invention is to provide a medical tissue-marker which enables the identification of a location even from the outside of an organ, can remain topical over a long period, and enables the easy identification of a marked location within the whole organ; also to provide a manufacturing method for the medical tissue-marker. The medical tissue-marker as in the present invention includes a vesicle formed by the synthesis of a phospholipid and a near infrared fluorescent dye, and an emulsion formed by the synthesis of the phospholipid and an X-ray contrast medium, and has agglomerated clusters wherein the vesicle and the emulsion are contained in a hydrophilic solvent and a plurality of capsules are formed by means of an emulsifier. | 2014-08-07 |
20140219925 | POLYMER PARTICLES OR NANO-VECTORS AND USE THEREOF AS A DRUG AND/OR DIAGNOSTIC AGENT - Novel polymer nanovectors or particles and use thereof as medication and/or diagnostic agents. | 2014-08-07 |
20140219926 | Biodegradable Iron Oxide Nanoparticle Gel for Tumor Bed Therapy - A biodegradable iron oxide nanoparticle gel for hyperthermia treatment of cancer includes a polysaccharide-based carrier matrix and starch-coated iron oxide nanoparticles. The gel has sufficient deformability to integrate into a diffuse tumor site, adheres to tissue and has sufficient mechanical properties to remain in place during hyperthermia treatment. The gel releases iron oxide nanoparticles for uptake by cancerous cells at the tumor margin. | 2014-08-07 |
20140219927 | Hair Fixative Compositions - A hair fixative composition includes a hair fixative polymer and a solvent system where the solvent system includes ethanol and another non-aqueous solvent in a weight ratio in a range of about 80:20 to about 20:80 of ethanol to the other non-aqueous solvent, and optionally a propellant. | 2014-08-07 |
20140219928 | TOPICAL OILY FOAM COMPOSITIONS - Topical alcohol-free thermo labile oily foam composition comprising (i) at least one active pharmaceutical ingredient or ectoparasitic active ingredient; (ii) at least about 20% w/w of at least one lipophilic component; (iii) at least about 10% w/w of at least one non-ionic surfactant; (iv) at least about 0.5% w/w of at least one fatty alcohol or fatty acid or ester thereof with melting point above 30° C., and; (v) at least about 7% w/w of propellant selected from propane, butane, isobutene and combinations thereof; said composition optionally comprising at least about 5% to about 70% w/w of a hydrophilic component, optionally comprising up to about 5% w/w hydrogenated oil and optionally comprising a penetration enhancer | 2014-08-07 |
20140219929 | OLEAGINOUS PHARMACEUTICAL AND COSMETIC FOAM - The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such compositions. The foamable composition includes at least one solvent selected from a hydrophobic solvent, a silicone oil, an emollient, a co-solvent, and mixtures thereof, wherein the solvent is present at a concentration of about 70% to about 96.5% by weight of the total composition, at least a non-ionic surface-active agent at a concentration of about 0.1% to less than about 10% by weight of the total composition; at least one gelling agent at a concentration of about 0.1% to about 5% by weight of the total composition; a therapeutically effective amount of at least one active agent; and at least one liquefied or compressed gas propellant, at a concentration of about 3% to about 25% by weight of the total composition. | 2014-08-07 |
20140219930 | Cooling Enhancing Compositions - The following invention relates to a taste enhancer and a method of enhancing taste. The invention relates the use of a cooling enhancing composition which provides cooling enhancement when combined with other cooling compounds. | 2014-08-07 |
20140219931 | P-MENTHANE-3,8-DIOL ISOMER MIXTURE, COOLING SENSATION COMPOSITION COMPRISING THE SAME, AND PRODUCT COMPRISING THE COOLING SENSATION COMPOSITION - The present invention relates to a p-menthane-3,8-diol isomer mixture 50% by mass or more of which is constituted of (1S)-isomers and a cooling sensation composition containing this mixture. The present invention also relates to a flavor and/or fragrance composition, food, beverage, cosmetic, daily use product, oral cavity composition, or pharmaceutical containing the p-menthane-3,8-diol isomer mixture in an amount of 0.0001 to 90% by mass. | 2014-08-07 |
20140219932 | Enamel Protectant and Repair Toothpaste - Substantially aqueous-free, enamel protectant and enamel repair toothpastes containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein: (a) substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and (b) said toothpastes indicate substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels. | 2014-08-07 |
20140219933 | COMBINATION OF AN OXIDANT, A PHOTOSENSITIZER AND A WOUND HEALING AGENT FOR ORAL DISINFECTION AND TREATMENT OF ORAL DISEASE - The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier. | 2014-08-07 |
20140219934 | BOTANICAL TOOTH WHITENER COMPOSITION AND METHOD FOR TREATING DISCOLORED OR STAINED TEETH - A botanical tooth whitener composition comprises a quantity of camellia oil, a flavoring, and a thickening agent. The composition is comprised of natural substances and is generally free of chemical additives commonly found in related products. The composition may be used to reduce tooth discoloration or staining by brightening the teeth exposed thereto. A method of treating discolored or stained teeth comprises the steps of obtaining a botanical tooth whitener composition, dispensing a quantity thereof onto or into an applicator, and applying the composition to a tooth or teeth via the applicator. The applicator may be any of a spray bottle, brush pen, toothbrush, and dental tray. | 2014-08-07 |
20140219935 | TOPICAL BIOADHESIVE FORMULATIONS - The present invention relates to topical bioadhesive formulations comprising low viscosity, non-liquid crystalline, mixtures of: a) at least one neutral diacyl lipid and/or at least one tocopherol; b) at least one phospholipid; c) at least one biocompatible, oxygen containing, low viscosity organic solvent; wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The invention additionally relates to a method of delivery of an active agent comprising administration of a preformulation of the invention, a method of treatment comprising administration of a preformulation of the invention and the use of a preformulation of the invention in a method for the manufacture of a medicament. | 2014-08-07 |
20140219936 | OIL-IN-WATER EMULSION HAVING IMPROVED SENSORY PROPERTIES - An oil-in-water emulsion includes, for 100 wt % thereof: a) 0.1 to 10 wt % of an emulsifying system including, for 100 wt % thereof: (i) 5 to 95 wt % of the mixture of the reaction products of a reducing sugar and 1,12-octadecanediol essentially consisting of hydroxyl-octadecyl polyglycosides of formula (I): HO—R—O-(G) | 2014-08-07 |
20140219937 | TOPICAL SUNSCREEN COMPOSITIONS - Substantially anhydrous compositions including at least 10% by weight of a C | 2014-08-07 |
20140219938 | SUNSCREENS - The present invention relates to a composition for topical application in the form of an oil-in-water (O/W) emulsion comprising in a physiologically acceptable medium at least a dibenzoylmethane derivative, an amino substituted hydroxybenzophenone derivative and a benzotriazol derivative. | 2014-08-07 |
20140219939 | LIQUID SKIN-CONDITIONING COMPOSITION - The present invention provides an external-use liquid skin-conditioning composition that not only reduces the sticky and friction sensations caused by the inclusion of tranexamic acid, but also has a rich body without feeling slimy and softens the skin after use. The composition comprises (A) 0.5 to 5 mass % of at least one hem selected from a group consisting of tranexarnic acid and derivatives thereof and (B) 0.005 to 1.5 mass % of carboxymethylcellulose, has a viscosity of no greater than 500 mPa·s at 30° C., and is transparent or semitransparent with an L value between 50 and 100 inclusive. Preferably the composition contains only carboxymethylcellulose as a thickener. | 2014-08-07 |
20140219940 | Skin-Lightening Agent - Provided are a very safe skin whitening agent, melanin production inhibitor, and dopa oxidase activity inhibitor. Use of kitsunenomago or an organic solvent extract thereof to inhibit the dopa oxidase activity. | 2014-08-07 |
20140219941 | COSMETIC POWDER COATED WITH ALGINIC ACID AND METHODS OF MAKING THE SAME - The present disclosure relates generally to cosmetic powders having improved dispersibility, feel, and stability in which the powders are surface modified with at least one alginic acid, or salt form thereof. The powders may be used in cosmetic compositions such as a powder foundation skin toner, skin lotion, or body wash. | 2014-08-07 |
20140219942 | SUNSCREENS - The present invention relates to a composition for topical application comprising at least a benzotriazol derivative and a cosmetic solvent selected from the group consisting of benzoate solvents such as phenethyl benzoate, dimethyl capramide and diethylhexyl 2,6-naphthalate. Furthermore, the invention relates to the use of specific benzotriazol derivatives to mask the off-odor of cosmetic solvents such as particularly phenethyl benzoate, dimethyl capramide and diethylhexyl 2,6-naphthalate. | 2014-08-07 |
20140219943 | COMPLEX FOR IMPROVEMENT OF DISTRIBUTION AND RETENTION OF FRAGRANCES INTO KERATINOUS MATTER, USES, COSMETIC PRODUCT AND METHOD FOR IMPROVEMENT OF DISTRIBUTION AND RETENTION OF FRAGRANCES INTO KERATINOUS MATTER - The present invention refers to a complex for the improvement of distribution and retention of fragrances into keratinous matter comprising (a) C10-C18 alkyl pyrrolidone, (b) at least one polyol compound and (c) at least one fatty alcohol, as well as uses, products, and related methods. The complex of the present invention homogeneously distributes fragrance into the keratinous matter, achieving a better interaction between the fragrance and the keratinous substrate, and better and longer perception of it, ensuring greater durability of the fragrance. | 2014-08-07 |
20140219944 | Method For Forming Volumizing, Fixative, And Conditioning Particles For Fine Hair - A method for forming a large particle complex comprising the steps of combining a hydrolyzed corn starch polymer, a starch/cellulose polymer, a hydrogenated phospholipid, and gum arabic in a cosmetically acceptable carrier to form a premix composition; heating said premix to about 85° C. for about 15 minutes; and cooling the composition to room temperature. The particle complex is useful as a component of a sprayable composition which provides volumizing, hair fixing, and conditioning as a leave-on treatment for human hair. | 2014-08-07 |
20140219945 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE PARTICULAR AMPHOTERIC POLYMER AND AT LEAST ONE PARTICULAR CONDITIONING AGENT - Cosmetic composition comprising at least one particular amphoteric polymer and at least one particular conditioning agent The present invention relates to a cosmetic composition comprising: a)—one or more amphoteric polymers comprising a repetition of: (i) one or more units obtained from a monomer of (meth)acrylamide type, (ii) one or more units obtained from a monomer of (meth)acrylamidoalkyltrialkylammonium type, and (iii) one or more units obtained from an acidic monomer of (meth)acrylic acid type, the said amphoteric polymer(s) being present in the composition in an amount of between 0.01% and 10% by weight relative to the total weight of the composition, and b)—one or more conditioning agents chosen from plant oils, mineral oils, non-volatile linear silicones of polydialkylsiloxane structure, non-volatile linear silicones of polydiarylsiloxane structure, non-volatile linear silicones of polyalkylarylsiloxane structure, fatty acid diesters of polyethylene glycol comprising from 2 to 50 oxyethylene units, and a mixture thereof. The invention also relates to a cosmetic process for treating keratin fibres using such a composition, and to a cosmetic use for facilitating the styling and/or for improving the suppleness, smoothness and/or disentangling of the hair. | 2014-08-07 |
20140219946 | Use Of Microemulsions In Cosmetic Cleaning Compositions - Provided are microemulsions comprising: (a) at least one alkyl (oligo)glycoside, (b) at least one cosurfactant different from (a), (c) at least one non-water-soluble organic oil component, (d) at least one moisturizing agent, (e) and water. | 2014-08-07 |
20140219947 | SCENT AND ULTRA-VIOLET ELIMINATION FORMULATION - An odor and ultra-violet light elimination formulation for application to hunting garments and equipment. The formulation has an ultra-violet light inhibitor which absorbs ultra-violet light emissions. The formulation also has a polymer providing a protective layer against odor causing molecules. And the formulation has a quaternary ammonium for eliminating odors and serving as a liquid chemical carrier for other formulation components. | 2014-08-07 |
20140219948 | DEODORANT SPRAY - A deodorant comprises triethyl citrate, zinc glycinate, and water. The deodorant has a pH of 5.5 to 6.5. | 2014-08-07 |
20140219949 | PHARMACEUTICAL COMPOSITIONS COMPRISING IODINE AND STEROID AND USES THEREOF FOR SINUS DISEASES - The present invention provides pharmaceutical compositions comprising an iodine-containing compound and a steroid, useful for treating a clinical symptom in a patient's airway (e.g., nose, lung, and sinus), as well as methods for using the same. | 2014-08-07 |
20140219950 | ENHANCED TRANSPORT USING MEMBRANE DISRUPTIVE AGENTS - Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes, coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and/or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and/or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontophoresis, and/or electrophoresis can also be used with the disrupting agents. | 2014-08-07 |
20140219951 | AMIDO-AMINE DENDRIMER COMPOSITIONS - Amide compounds, amide polymers and compositions including amide compounds and amide polymers may be used to bind target ions, such as phosphorous-containing compounds in the gastrointestinal tract of animals. In some cases, the amide polymers may be amido-amine dendrimers that may be formed via a series of iterative reactions. | 2014-08-07 |
20140219952 | METHODS OF TREATMENT USING STEM CELL MOBILIZERS - The present invention relates to the field of stem cells. In one aspect, the present invention provides methods of treating a subject with acute liver injury comprising administering to the subject a therapeutically effective amount of at least one stem cell mobilizer. In particular embodiments, the subject is treated with plerixafor and G-CSF | 2014-08-07 |
20140219953 | ADHESIVE CELL TISSUE GELS - Described herein is a cell tissue gel cross-linked with a cross-linking agent, and a quenching agent bound to a reactive group of the cross-linking agent. | 2014-08-07 |
20140219954 | DRY POWDER FORMULATIONS OF ORGANIC MACROMOLECULES - The present invention relates to methods for making a stabilized powder formulation for inhalation comprising a macromolecule in lyophilized form, a crystalline carrier material, and magnesium stearate. | 2014-08-07 |
20140219955 | FUSION MOLECULES AND IL-15 VARIANTS - The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making thesuch proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention. | 2014-08-07 |
20140219956 | PRO-DRUG FORM (P2PDOX) OF THE HIGHLY POTENT 2-PYRROLINODOXORUBICIN CONJUGATED TO ANTIBODIES FOR TARGETED THERAPY OF CANCER - Disclosed are methods, compositions and uses of conjugates of prodrug forms of 2-pyrrolinodoxorubicin (P2PDox) with antibodies or antigen-binding fragments thereof (ADCs), with targetable construct peptides or with other targeting molecules that are capable of delivering the P2PDox to a targeted cell, tissue or pathogen. Once delivered to the target cell, the ADC or peptide conjugate is internalized, a highly toxic 2-pyrrolinodoxorubicin (2-PDox) is released intracellularly. The P2PDox-peptide or ADC conjugates are of use to treat a wide variety of diseases, such as cancer, autoimmune disease or infectious disease. | 2014-08-07 |
20140219957 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF IMMUNE DISORDERS - The invention features methods of treating an immune disorder characterized by elevated Pin1 marker levels in a subject by administering a retinoic acid compound. Additionally, the invention features methods of treating immune disorders (e.g., immune disorders characterized by elevated Pin1 marker levels) by administering a retinoic acid compound in combination with an anti-inflammatory, anti-viral, or anti-microbial compound. | 2014-08-07 |
20140219958 | 5, 6-D2 URIDINE NUCLEOSIDE/TIDE DERIVATIVES - In one aspect, the invention provides compounds represented by Formula I, | 2014-08-07 |
20140219959 | HUMAN FUSION PROTEINS COMPRISING INTERFERONS AND TARGETED MODIFIED UBIQUITIN PROTEINS - The present invention relates to fusion proteins in which a pharmaceutically active component is fused to an antibody mimetic. The invention specifically concerns fusion proteins comprising interferons or biologically active muteins thereof and modified hetero-dimeric ubiquitin proteins as specific targeting domain. The invention further relates to these fusion proteins for use in medicine, in particular for use in the treatment of cancer or infectious diseases. The invention is further directed to pharmaceutical compositions comprising a pharmaceutically acceptable carrier in combination with such fusion proteins, and in combination with cancer therapeutic agents. Moreover, the invention relates to a method for the generation of said fusion proteins. | 2014-08-07 |
20140219960 | NOVEL COMPOSITION FOR PREVENTING OR TREATING HEPATITIS C VIRUS, REGULATING PHOSPHORYLATION OF REPLICASE - The present invention relates a novel composition for preventing or treating hepatitis C virus, regulating the phosphorylation of a replicase. More specifically, it is possible to prevent or treat hepatitis C using a novel PRK2 inhibitor discovered through structure modeling, and to prevent or treat hepatitis C, particularly, interferon-insensitive hepatitis C through coadministration of an Hsp90 inhibitor. | 2014-08-07 |
20140219961 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING INTERFERON ALPHA CONJUGATE - A method for preventing or treating a cancer includes administering an anti-cancer pharmaceutical composition including an interferon alpha or a polymer conjugate thereof. The pharmaceutical composition can be co-administered with anti-cancer agents. The interferon alpha conjugate shows a longer in vivo half-life and a more excellent anti-cancer activity than the conventional interferon alpha, and in particular, its co-administration with an anti-cancer agent such as gemcitabine has synergistic inhibitory effects on cancer cell growth and proliferation so as to exhibit a remarkably excellent anti-cancer activity. Further, the anti-cancer pharmaceutical composition has excellent in vivo half-life and anti-cancer activity to greatly reduce administration frequency. Co-administration of an anti-cancer agent and the interferon alpha conjugate having excellent anti-cancer activity reduces administration dose of anti-cancer agent so as to reduce side effects of anti-cancer agent and increase treatment compliance of patient. | 2014-08-07 |
20140219962 | POROUS CHITOSAN SCAFFOLDS AND RELATED METHODS - Porous chitosan scaffold having high mechanical strength, methods for making the porous chitosan scaffold, and method for using the porous chitosan scaffold. | 2014-08-07 |
20140219963 | Extracellular Matrix-Derived Gels and Related Methods - Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient. | 2014-08-07 |
20140219964 | METHODS FOR INDUCING CARDIOMYOCYTE PROLIFERATION - Methods for inducing cardiomyocyte proliferation, e.g., in vivo, by administering a composition comprising miRNA17-92 cluster oligonucleotides, e.g., miR-19a oligonucleotides, miR-19b oligonucleotides, or both miR-19a and miR-19b oligonucleotides. | 2014-08-07 |
20140219965 | CONTROLLING APPETITE, PROMOTING WEIGHT LOSS, REDUCING BODY FAT, AND/OR IMPROVING GLUCOSE TOLERANCE - A method for treating obesity, insulin sensitivity, and related conditions involves administering to the subject a bacterium for overexpressing a N-acyl-phosphatidylethanolamine (NAPE) and/or a N-acylethanolamine (NAE). A composition includes a bacterium for overexpressing a N-acyl-phosphatidylethanolamine (NAPE) and/or a N-acylethanolamine (NAE); and an ingestible vehicle in which the bacterium is provided. | 2014-08-07 |
20140219966 | FECAL LACTOFERRIN AS A BIOMARKER FOR DETERMINING DISEASE SEVERITY AND FOR TREATING INFECTION IN PATIENTS WITH CLOSTRIDIUM DIFFICILE DISEASE - Clostridium difficile disease involves a range of clinical presentations ranging from mild to self-limiting diarrhea to life-threatening pseudomembranous colitis and megacolon. Cases of C. difficile are treated differently depending on severity of disease. Mild and moderate cases may be treated with metronidazole while moderate-to-severe and relapsing cases are often treated with vancomycin or fidaxomicin. The presence of C. difficile disease is detected using a biomarker panel that includes C. difficile antigen (GDH), toxins A and B, and fecal lactoferrin. In patients suspected of C. difficile disease, if GDH is detected indicating the presence of C. difficile, and then toxins A and/or B are detected to indicate toxigenic C. difficile and support a diagnosis of C. difficile-associated disease, fecal lactoferrin concentrations are measured to determine severity of the disease by indicating the amount of intestinal inflammation. | 2014-08-07 |
20140219967 | Poly (3-Hydroxybutyrate/3-Hydroxyvalerate) of Lowered Crystallinity for Use in Animal Feed - Animal feed conversion ratio can be increased and blood glucose levels can be decreased by feeding an efficacious amount of dispersible amorphous poly(3-hydroxybutyrate/3-hydroxyvalerate). | 2014-08-07 |
20140219968 | NOVEL SALMONELLA BACTERIOPHAGE COMPOSITIONS AND USES THEREOF - The present invention relates to novel bacteriophages and bacteriophage cocktails containing the novel bacteriophages and or parts and/or products of them, all of them belonging to the Caudovirales order. The novel bacteriophages and the bacteriophage cocktails containing the novel bacteriophages and or parts and/or products of them are | 2014-08-07 |
20140219969 | CELL THERAPY FOR THE TREATMENT OF NEURODEGENERATION - Methods are described for the isolation and selection of a heterogeneous bone marrow cell population, called NCS-01, that is effective at treating neurodegeneration. For example, NCS-01 cells are shown to treat neurodegeneration caused by ischemia. In vivo studies demonstrate that selected NCS-01 cell populations treat neurodegeneration in a standard rat middle cerebral artery occlusion (MCAO) animal model under conditions of transient or permanent total arterial occlusion. These studies also disclose that when the neurodegeneration is caused by ischemic stroke, combining the administration of a selected NCS-01 cell population with thrombolytic agents and/or mechanical methods of clot removal leads to a decrease in the volume of infarction caused by acute onset neurodegeneration. The disclosed cell therapy promises to make a significant clinical impact on patient survival after stroke. | 2014-08-07 |
20140219970 | TREATMENT OF SARCOIDOSIS USING PLACENTAL STEM CELLS - Provided herein are compositions and methods of treating individuals having sarcoidosis or a sarcoidosis-related disease or disorder, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein. Also provided herein are kits comprising said cells or a composition thereof. | 2014-08-07 |
20140219971 | ALGAL PRODUCED MALARIAL TRANSMISSION BLOCKING VACCINES - The present invention relates to the production of malaria transmission blocking vaccines in single-celled green algae, particularly algae of the genus | 2014-08-07 |
20140219972 | TISSUE ENGINEERING USING PROGENITOR CELLS TO CATALYZE TISSUE FORMATION BY PRIMARY CELLS - Methods of regenerating tissue using progenitor cells in combination with primary cells from a target tissue are disclosed. In particular, progenitor cells catalyze proliferation and tissue production by primary cells allowing the use of fewer primary cells from a target tissue for effective tissue regeneration. Cell-based therapies combining progenitor cells and primary cells can be used for repair and regeneration of damaged tissue and organs for treating bodily injuries and degenerative diseases. For example, adipose-derived stem cells and neonatal articular chondrocytes, co-encapsulated in mixed or bilayered cultures in a hydrogel comprising chondroitin sulfate methacrylate and poly(ethylene)glycol diacrylate, generated cartilage that could be used for treatment of traumatic injuries or diseases involving cartilage degeneration. Moreover, the inventors showed that progenitor cells could be used to stimulate cartilage formation with a minimal number of primary cells, as few as 1% or less, in mixed cultures containing primary cells and progenitor cells. | 2014-08-07 |
20140219973 | Composite Hydrogel-Clay Particles - A nanocomposite hydrogel formed from free radical dissociation of an initiator and polymerisation of a water soluble monomer. The resulting hydrogel finds particular application within the medical field for both soft and hard tissue repair in human and animals. The hydrogel is particularly advantageous for spinal disc repair. | 2014-08-07 |
20140219974 | TARGETED DELIVERY OF PROTEINS ACROSS THE BLOOD-BRAIN BARRIER - Embodiments of the invention are directed to compositions comprising a peptide sequence, or a nucleic acid encoding the same, wherein the peptide sequence includes a receptor-binding region of apolipoprotein E (apoE), or a sequence variant or fragment thereof, for directing delivery of a given protein or therapeutic across the blood brain barrier. Embodiments of the invention are also directed to methods of using the compositions for treating or preventing a neurological disorder, disease, or symptom in a subject in need thereof. | 2014-08-07 |
20140219975 | SWITCH COSTIMULATORY RECEPTORS - The present invention relates generally to a fusion protein that when displayed on a cell can convert a negative signal into a positive signal in the cell. The fusion protein is a chimeric protein in that the protein comprises at least two domains, wherein the first domain is a polypeptide that is associated with a negative signal and the second domain is a polypeptide that is associated with a positive signal. Thus, the invention encompasses switch receptors that are able to switch negative signals to positive signals for enhancement of an immune response. | 2014-08-07 |
20140219976 | METHODS AND COMPOSITIONS FOR TREATMENT OF RETINAL DEGENERATION - Disclosed herein are methods and compositions for treating glaucoma, using descendents of marrow adherent stem cells that have been engineered to express an exogenous Notch intracellular domain. | 2014-08-07 |
20140219977 | USE OF LIVE BACTERIA FOR GROWTH PROMOTION IN ANIMALS - The present invention relates to the use of F4 | 2014-08-07 |