32nd week of 2022 patent applcation highlights part 8 |
Patent application number | Title | Published |
20220249292 | DEVICES FOR BLEEDING REDUCTION AND METHODS OF MAKING AND USING THE SAME - In some embodiments, a system includes an applicator pad, an application device (e.g., a grip), and a reservoir. The grip can be releasably couplable to the applicator pad and configured to dispose the applicator pad against a wound of a subject such that pressure can be transferred to the wound via the applicator pad to enhance hemostasis. The reservoir can be configured to contain medication to be released to the wound via the applicator pad. | 2022-08-11 |
20220249293 | WOUND TREATMENT SYSTEM - A wound treatment system includes a wound dressing, a negative-pressure source, a light-emitting device, an image recognition module, and a control module. The wound dressing includes a housing with an opening, and a barrier layer with a conduit pathway separating the inside of the housing from the opening to form a receiving space. The negative-pressure source is fluidly connected to the wound dressing to remove tissue exudate of the wound. The light-emitting device is disposed in the receiving space, optically coupled to the barrier layer and can emit light of different wavelength bands as the detection light required by the image recognition module disposed on a side of the opening of the housing of the wound dressing and provide specific wavelengths of phototherapy required by different stages of the wound. | 2022-08-11 |
20220249294 | ABSORBENT COMPONENT - The present invention generally relates to an absorbent component ( | 2022-08-11 |
20220249295 | MULTI-LAYER ABSORBENT CORES AND METHODS OF MANUFACTURE - Multi-layered absorbent bodies and methods of manufacture are disclosed. An absorbent body may comprise a top, liquid permeable covering material, a bottom covering material, a reinforcing material disposed between the top covering material and the bottom covering material, the reinforcing material bonded directly to the top covering material by a first adhesive layer and bonded directly to the bottom covering material by a second adhesive layer, and superabsorbent material disposed between the top covering material and the bottom covering material, wherein between about 30% and about 85%, by weight, of the total amount of superabsorbent material disposed between the top covering material and the bottom covering material is stabilized within the reinforcing material, as determined according to the SAM Stabilization Location Test Method. | 2022-08-11 |
20220249296 | MOISTURE DETECTION AND ESTIMATION WITH MULTIPLE FREQUENCIES - A method of moisture detection and estimation in an absorbent article with use of multiple frequencies is provide that comprises: applying, by capacitive coupling, drive signal of multiple frequencies to a drive electrode in the absorbent article; sensing, by capacitive coupling, sense signal of the multiple frequencies from a sense electrode in the absorbent article; detecting the first wetness event in the absorbent article with use of sense signal of a frequency of the multiple frequencies; and detecting the saturation of the absorbent article with use of sense signal of another frequency of the multiple frequencies. | 2022-08-11 |
20220249297 | APPARATUS FOR THE DETECTION OF MOISTURE - A moisture management apparatus monitors an area for moisture events and wirelessly transmits moisture-related information to one or more notification devices. An embodiment of the moisture management apparatus includes a substrate and one or more sensors supported by the substrate. The sensor(s) emit wireless signals indicative of the moisture-related information. A sensor event communication system forwards the sensor signals to another device, such as a notification device. The sensor event communication system may monitor other types of patient events. Portions of the moisture management apparatus and/or the moisture event communication system may be embodied in a patient support apparatus, such as a bed. | 2022-08-11 |
20220249298 | SMART ABSORBENT ARTICLE, COMPONENTS, AND PROCESS OF MAKING - A substrate suitable for incorporation into an absorbent article for automatic detection of wetness events therein, the substrate comprising a first surface capable of being arranged proximal to a body facing side of the absorbent article and a second surface opposite said first surface and capable of being arranged proximal to a garment facing side of said absorbent article, said substrate comprising a plurality of sensor tracks disposed on said first surface and said sensor tracks comprising: at least one central track extending parallel to a length of the substrate and parallel to a longitudinal axis crossing a first end and a second end of the substrate; at least two side tracks extending parallel to the central track and oppositely arranged such that the central track extends therebetween; and wetness sensing tracks extending outboard of said two side tracks, wherein said central track, said side tracks, and said wetness sensing tracks are in electrical communication via one or more shortening elements positioned proximal to said second end and distal from said first end, and wherein the substrate is connectable to a clip-on data processing module at a position proximal to said first end and distal from said shortening elements such to form a closed electrical circuit, typically for measuring resistance and/or capacitance therethrough. In an embodiment said substrate consists of a liquid impermeable backsheet, preferably a breathable liquid impermeable backsheet. | 2022-08-11 |
20220249299 | Child and adult leak-proof garments made with an inner absorbent fabric - The novel dual-layer garment includes an outer layer made from a fluid-repellant or leak-proof fabric and an inner absorbent layer assembled therewith. The inner layer is made to slow down fluid absorption as compared to regular baby diapers in order to keep the child feeling wet for an extended, yet limited period of time. The adult version of the garment may feature several tight bands along the full length of the garment so as to compartmentalize several sections thereof and limit fluid runoff to avoid an outside leakage of fluids. | 2022-08-11 |
20220249300 | ABSORBENT ARTICLES WITH BACKSHEET GRAPHICS - An absorbent article having a front waist region with a front waist edge, a back waist region with a back waist edge, and a crotch region disposed between the front and back waist regions is disclosed. The absorbent article has a topsheet, a backsheet, and an absorbent core positioned between the topsheet and the backsheet and having a front end edge and a back end edge. The backsheet has a plurality of graphics. Graphics of a first portion of the plurality of graphics disposed on a portion of the backsheet between the back waist edge of the absorbent article and the back end edge of the absorbent core have an opacity less than graphics of a second portion of the plurality of graphics disposed on a portion of the backsheet between the back end edge of the absorbent core and the front waist edge of the absorbent article. | 2022-08-11 |
20220249301 | REUSABLE SHELL FOR ABSORBENT ARTICLE - The following disclosure presents a wearable reusable shell, configured to hold an absorbent article, for use particularly in economically disadvantaged communities and/or communities with a water shortage. The wearable reusable shell comprises a base having a pair of wings extending from a center portion, an inner layer positioned along the center portion of the base, and an outer layer positioned along the center portion of the base and on top of the inner layer. Extending over the outer layer is at least one band configured to hold an disposable absorbent article in place. The present disclosure also presents a hybrid sanitary napkin (and a kit therefor) and methods of making and using a wearable reusable shell. | 2022-08-11 |
20220249302 | ABSORBENT BODY WITH TOPSHEET COMPOSITE - Disclosed is an absorbent body for an absorbent article, comprising: 1) a first topsheet facing the wearer, the first topsheet being a water permeable nonwoven layer comprising eccentric bicomponent fibers, and having a basis weight of at least about 20 gsm, 2) a second topsheet disposed on the garment facing side of the first topsheet, the second topsheet being a nonwoven layer comprising spunbond fibers and having a positive, at least about 100%, Accumulative One-way Transport Capacity according to the National Standards of the People's Republic of China GB/T 21655.2-2009, wherein the basis weight of the second topsheet is the same or smaller than the basis weight of the first topsheet; 3) an absorbent core disposed on the garment facing side of the second topsheet, and 4) a water impermeable backsheet disposed on the garment facing side of the absorbent core. | 2022-08-11 |
20220249303 | REUSABLE SANITARY NAPKIN AND A COMBINED PANTY AND REUSABLE SANITARY NAPKIN UNDERWEAR - A reusable sanitary napkin includes an outer body, a first absorbent fabric component, and a skin-contacting fabric component. The outer body includes a base layer component and a top waterproof layer component. The top waterproof layer component is attached to a top surface of the base layer component, and has a through hole. The first absorbent fabric component is attached to the top surface of the base layer component, and is registered with the through hole. The skin-contacting fabric component is attached between the first absorbent fabric component and the top waterproof layer component. A boundary of the through hole is disposed on the skin-contacting fabric component. | 2022-08-11 |
20220249304 | THREE DIMENSIONAL NONWOVEN AND ABSORBENT ARTICLES HAVING THE SAME - The present disclosure relates to a three dimensional nonwoven comprising a protruded area comprising a first area having a first light reflectance and a second area having a second light reflectance. The three dimensional nonwoven comprises a recess comprising a third area having a third light reflectance, wherein the first light reflectance is different from the second light reflectance, as measured according to Light Reflectance Test. The present disclosure also related to an absorbent article comprising the three dimensional nonwoven. | 2022-08-11 |
20220249305 | Clean Diaper and Wipe Dispensing Cabinet - A diaper and wipe dispensing cabinet is provided. The device includes a housing centrally disposed on a panel. The housing further includes a front door. The front door provides access to an interior volume of the housing in which diapers are stored. A lower end of the interior volume includes a spring loaded platform that biases a spring upwardly, thereby forcing stored diapers upwardly within the interior volume toward a wide upper region of an aperture disposed on the front door. The wide upper region allows for easy retrieval a diaper when the front door is secured to the housing via a latch. An upper portion of the housing further includes a plurality of members extending upwardly above the housing defining a recessed area. The panel further includes a plurality of shelves for additional storage and at least one hook to attach the device to a support structure. | 2022-08-11 |
20220249306 | WHEEL CHAIR FOR CONTACTLESS BOARDING INTO A VEHICLE - A wheelchair for onboarding a wheel chair person into a vehicle including a wheelchair and a king pin adapted to the wheelchair. The kingpin may be configured for positioning within an opening of a fifth wheel adapted to a vehicle configured for moving the wheelchair into a vehicle. Alternatively, a fifth wheel may be adapted to the wheelchair and a king pin to the vehicle. A system for onboarding a wheel chair person may include a wheelchair, a carriage, a fifth wheel, a king pin, a ramp latch mechanism, a fifth wheel latch mechanism, a processor, memory, and a switching mechanism. Instructions executable by the processor may: select ramp latch mechanism, determine ramp status, and active up/down the ramp; select fifth wheel latch mechanism, determine fifth wheel status, and on/off the fifth wheel. Other features include camera, dash panel control, no-contact panels, connection with external utility, and other features. | 2022-08-11 |
20220249307 | A Reclining Chair and Method of Use Thereof - A reclining chair includes a frame and a back part with a back support slidably connected to a back frame hinged on a frame rotation point on the frame. A seat part, including a seat frame and a seat, is pivotably connected to the back frame at a chair joint. A reclining mechanism includes an arm pivot point fixed to the frame. A first arm extends from the arm pivot point to a second arm at an arm suspension point. The second arm is pivotably connected to the chair joint. When the back part reclines from an upright position, the back frame rotates, the first arm rotates, the chair joint moves towards the seat part, and a connecting arm extending from the back support and mechanically linked to the first arm and the second arm pulls the back support so the back support slides towards the seat part. | 2022-08-11 |
20220249308 | Lift for Water Entry/Exit and Methods of Manufacture and Use Thereof - A method for mechanically lowering a person into and out from a structure having a water level, a deck, and an interior wall includes a waterproof lift and drive assembly, and the steps of connecting the lift to a base housing having an upper surface such that, in a lowered state, a lifting beam is at least partially contained within the base housing and, in a raised state, at least a portion of the lifting beam is above the upper surface at a given height, fixing the base housing to a wall of the structure to place the upper surface below the waterline such that, in the lowered state, the lifting beam and the seat assembly are completely submerged in the water and, in the raised state, the bottom seat surface is above the waterline and deck sufficient to permit a person to sit upon the chair. | 2022-08-11 |
20220249309 | METHOD OF SECURING A PATIENT ONTO AN OPERATING OR SURGICAL TABLE WHEN THE PATIENT IS IN A POSITION, SUCH AS TRENDELENBURG, FOR A HIP PROCEDURE AND APPARATUS THEREFOR INCLUDING A KIT - Method of securing a patient onto an operating or surgical table when the patient is in a position for a hip procedure and apparatus therefor including a kit. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. § 1.72(b). As stated in 37 C.F.R. § 1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used f or interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner. | 2022-08-11 |
20220249310 | SURGERY PILLOW AND DEVICE COMBINING ENDOTRACHEAL TUBE HOLDER, BITE GUARD, AND PATIENT EYE PROTECTOR - A surgery apparatus includes a resilient foam pillow having an arrangement of labeled tabs for holding lines leading to/from a patient during and after surgery. A central cutout area in the pillow accommodates the patient's eyes, nose and mouth when in the prone position. Left and right channels in the foam pillow extend from a top edge of the pillow to the central cutout area for holding a breathing tube system. The foam pillow further includes a removably attachable chest support and opposite shoulder supports. A multipurpose holder device for placement on the patient's head has an arrangement of straps for securing an eye shield, a bite block and ventilator tube securing straps on the patient during surgery. | 2022-08-11 |
20220249311 | SEMI-SUPERVISED INTENT RECOGNITION SYSTEM AND METHOD - A robotic system configured to, in response to a state transition intention input, change the robotic system from operating in a first mode with sensitivity to detecting state transitions at a first sensitivity level to operating temporarily in a second mode with sensitivity to detecting state transitions at a second sensitivity level that is more sensitive than the first sensitivity level. The state transition intention input indicates an intention to make a state transition from a first state to a second state, with the second state being possible from a plurality of possible different states. | 2022-08-11 |
20220249312 | WALKING ASSISTANT DEVICE DEFORMABLE BASED ON THIGH SHAPE - A walking assistance device deformable based on a thigh shape includes a hip joint actuator, an upper thigh frame connected to the hip joint actuator and configured to receive power from the hip joint actuator and rotate about a first axis and rotate about a second axis intersecting the first axis, a motion frame connected to the upper thigh frame, the motion frame including a plurality of segment frames configured to rotate relative to each other, and a lower thigh frame connected to the motion frame. | 2022-08-11 |
20220249313 | MOBILITY ASSISTANCE DEVICE - A mobility assistance apparatus includes first and second frames positioned on left and right sides of a user; a hinge arm mechanism coupled to the first and second frames; and a securing unit or a walking seat coupled to the frames to transfer at least a portion of the user's body weight from the legs and to transfer weight through the user's hip or pelvis to the first and second frame enabling the user to stand or work for an extended period without requiring the user's arms to hold the frame. | 2022-08-11 |
20220249314 | TRAVEL ASSISTANCE SYSTEM - Apparatuses, systems and methods associated with a travel assistance system. A wearable personal navigation device may include a communication system, an indicator, and a processor coupled to the communication system and the indicator. The processor may be configured to generate a request for a navigation path from a location to a destination and transmit the request to a node of the network. The processor may be configured to determine the direction of travel from the location of the user based on a first navigation path received from the node of the network in response to the request, wherein the first navigation path includes at least one modification from a second navigation path, wherein the modification is based on data received by the network from a remote device that indicates an object, and cause the indicator to indicate the direction of travel. Other embodiments may be described and/or claimed. | 2022-08-11 |
20220249315 | TACTILE WARNING PANEL APPARATUS WITH SMART TECHNOLOGY - Multipurpose tactile warning panels for use in pedestrian walkways, and in particular tactile warning panels that are designed and built with multifunction/multipurpose capabilities that serve the visually impaired and enable the deployment of smart city technology by integrating tactile warning systems and subsurface enclosures that can withstand pressures of five (5) tons up to and exceeding sixty (60) tons and incorporate small cells, beacons, sensors, Fog Computing, electric energy generation, rechargeable power supplies, wireless M2M communication and a plethora of other smart city technologies. | 2022-08-11 |
20220249316 | PROVIDING ENHANCED IMAGES FOR NAVIGATION - Systems and methods relating to displaying images are disclosed. In one embodiment, sensor data is received via one or more sensors of a wearable head device comprising a display, the sensor data indicative of a surrounding environment of a user of the wearable head device. An image can be determined based on the sensor data, the image corresponding to the surrounding environment. A visibility of a first portion of the image corresponding to a first portion of the surrounding environment can be enhanced. Enhancing a visibility of a second portion of the image corresponding to a second portion of the surrounding environment can be forgone. The enhanced first portion of the image and a view of the second portion of the surrounding environment can be presented concurrently via the display of the wearable head device. | 2022-08-11 |
20220249317 | Hair Treatment Cap Apparatus - A hair treatment cap apparatus for product application and scalp massage for hair loss prevention includes a cap body having an inner layer and an outer layer joined at a cap edge and defining a cap bladder. The inner layer has a plurality of release apertures extending therethrough and the outer layer has a fill aperture extending therethrough to the cap bladder. The cap bladder holds a liquid hair treatment that is filled through the fill aperture and dispersed through the plurality of release apertures. The cap body is sufficiently flexible to conform to the shape of a wearer's head. The cap edge is elasticized to form a waterproof barrier around the user's head. A plurality of massage motors is coupled to the cap body to vibrate a plurality of nubs coupled to the inner layer. A controller coupled to the cap body operates the plurality of massage motors. | 2022-08-11 |
20220249318 | System and Method of Applied Contrasting Therapy to Pelvic Regions and Human Distal Anatomy - A system and method for providing Thermal contrast therapy are presented. The system may comprise a fluid membrane barrier, a human interface device (HID), fluid tubing, a pump, and a reservoir. The system may be operable to apply any combination of heat, cold, and pressurized compression, light energy, acoustic energy, and vibratory energy to a therapy recipient for treating anal-prostate-perineal and vaginal areas, as well as podological and other extremities. The system may be operable to impart a desired therapy temperature to the human interface device and to expand a membrane containing a therapy fluid. The expanded membrane may conform to the contours of a therapy site. Operation of the human interface device may be controlled using a remote-control device. The therapy recipient may be able to control the temperature of the fluid or gel, as well as reception of light energy, acoustic energy and vibratory pulsing energy to assist in treatment of one or more conditions. | 2022-08-11 |
20220249319 | PERSONAL USE EXTRACORPOREAL LOW FREQUENCY SHOCK WAVE INSTRUMENT AND METHODS OF USING SAME - A treatment device includes a housing having a longitudinal axis extending between a proximal end and a distal end, a motor, a drive shaft operatively coupled to the motor, a compression spring at least partially disposed about the drive shaft, a helical cam disposed adjacent the compression spring, the helical cam having at least one discontinuity, a hammer coupled to the helical cam and moveable therewith, and a tip disposed adjacent the distal end. | 2022-08-11 |
20220249320 | CARDIOPULMONARY RESUSCITATION DEVICE, CONTROL METHOD AND COMPUTER PROGRAM - According to an aspect, there is provided a cardiopulmonary resuscitation, CPR, device ( | 2022-08-11 |
20220249321 | BUBBLE BATH PHYSIOTHERAPY SYSTEM AND BATHTUB DEVICE THEREOF - A bathtub device for bubble bath physiotherapy, wherein the bathtub body is mounted on the bathtub body support. The exhaust system of the bathtub device is mounted in a space between the bathtub body and the bathtub body support. A fan is configured for delivering gas. The air suction inlet ends of the air suction pipe are configured to be in communication with the upper open side of the bathtub body, and the air suction outlet end is connected to the air inlet side interface device of the fan. The exhaust inlet end of the exhaust pipe is connected to the air outlet side interface device of the fan. The present invention further provides a bubble bath physiotherapy system comprising the bathtub device. By using the bathtub device, a safer bubble bath can be achieved. | 2022-08-11 |
20220249322 | AUTO CYCLE LUMBAR MASSAGE SYSTEM AND METHOD OF OPERATING THE SAME - The present invention relates to a piece of furniture within which a massage system has been incorporated so as to provide a person, sitting in the piece of furniture, with massage capabilities so as to relieve pressure, stress, and/or tension. The system comprises a lumbar actuator which is adapted to engage a lumbar portion of the piece of furniture, wherein the lumbar actuator will be cyclically activated in accordance with single or multiple frequencies or modes of operation so as to provide the person, sitting in the piece of furniture, with varying degrees of massage as may be desired by the user or person sitting in the piece of furniture. | 2022-08-11 |
20220249323 | METHOD OF NON-INVASIVE FIGURE CORRECTION AND METHOD OF MASSAGE FOR NON-INVASIVE FIGURE CORRECTION - A method for non-surgical body sculpting is claimed, characterized by the compilation of a set of measures for body sculpting, including cleansing the body; regulating water metabolism, diet and rest; unloading the gastrointestinal tract using mono-days and improving nutrition, taking vitamins and completely eliminating alcohol and foods that are digested in the stomach more than 2 hours, eating in portions of 150-200 ml, 5-6 times a day; physical exercises aimed at forming a healthy posture, tactile techniques of impact, while the muscles in the affected areas are pre-stimulated to improve blood circulation through physical exercises. A method of massage for non-surgical body sculpting, which includes the impact on fat deposits in the abdomen, peritoneum and weakened abdominal muscles in the form of a combination of physical activity and massage. | 2022-08-11 |
20220249324 | SUPPORT DEVICE FOR MANUAL THERAPY - The invention relates to a shoulder joint abduction fixation orthotic device. The shoulder joint abduction fixation orthotic device comprises a forearm support frame, a C-shaped upper arm bracket, an armpit support frame, a line-shaped armpit movable shaft and an adjustable support. The forearm support frame, the C-shaped upper arm bracket and the armpit support frame are integrally formed and used for supporting the forearm, the upper arm and the armpit on one side respectively, the line-shaped armpit movable shaft is arranged between the C-shaped upper arm bracket and the armpit support frame, and the adjustable support with one end connected with the C-shaped upper arm bracket and the other end connected with the armpit support frame is used for adjusting the shoulder joint abduction angle. The shoulder joint abduction fixation orthotic device can effectively overcome the defects of an existing orthotic device and ensure the postoperative effect of shoulder periarticular operations. | 2022-08-11 |
20220249325 | Medicament Container - The present disclosure relates to a medicament container for accommodating a liquid medicament. The medicament container includes an elongated container barrel defining a longitudinal direction and having a proximal end and a distal end. The proximal end is opposite the distal end. The container barrel includes a proximal container cross section at the proximal end. The elongated container barrel includes a distal container cross section at the distal end and the proximal container cross section is substantially identical to the distal container cross section. The medicament container further includes a seal arranged at the distal end and extending across the distal container cross section, and a retainer engaged with the seal and engaged with the elongated container barrel to fix the seal to the distal end. | 2022-08-11 |
20220249326 | IN-LINE MEDICATION CRUSHER FOR FEEDING TUBES - A syringe for injecting medication into a body includes a barrel having an inner diameter, a plunger for longitudinal movement within the barrel, the plunger having threads along at least a portion thereof for engaging internal threads of a thread ring, and a handle for rotating the plunger relative the barrel. An alternate embodiment of a syringe includes a barrel having internal threads positioned along a first interior wall, a diameter of the internal threads being greater than or equal to a diameter of a second interior wall of the barrel, and a plunger in sealing engagement with the second interior wall having threads for engaging the internal threads of the barrel. | 2022-08-11 |
20220249327 | BLISTER PACK CONTENT MONITORING - A cartridge includes a case housing a smartphone, a housing configured to hold a medication blister pack, and a detection method to record the blister pack being put in and out of the housing. | 2022-08-11 |
20220249328 | A device for equalizing the pressure inside a baby bottle - The invention relates to a device for equalizing the pressure inside a milk-containing baby bottle, by bottom venting, during suction from the nipple. | 2022-08-11 |
20220249329 | ENTERAL FLUID DELIVERY SYSTEM - Disclosed is a system for administrating fluids to a patient, such as an infant. The system comprises a container that defines a drip chamber, a source of nutritive fluid fluidically communicating with the drip chamber, and a tube connecting the drip chamber to the gastric cavity of a patient, the chamber including a membrane that is gas-permeable but that is resistant to fluid passage. The system allows fluids to be introduced to the patient and for gastric gases to be released while they are resistant to the leak and spillage. | 2022-08-11 |
20220249330 | Bluetooth Pacifier - The present invention relates to a Bluetooth pacifier for infants, toddlers, and children. More specifically, the Bluetooth pacifier includes a nipple, a collar and a handle. The Bluetooth pacifier includes an integrated Bluetooth microchip and a micro-USB charging port in the collar. The Bluetooth microchip periodically transmits Bluetooth Low Energy signals (BLE) to a paired electronic device. A software application installed in the electronic device processes the received BLE signals and associated RSSI values of the BLE signals for location tracking of the pacifier. When the pacifier and the electronic device are not in BLE range, the software application stores the last recorded (i.e. past-time) location of the pacifier. The micro-USB charger can be used for attaching a USB charger. | 2022-08-11 |
20220249331 | METHOD OF MANUFACTURING MONOMER COMPOSITION, RAW MATERIAL COMPOSITION, MONOMER COMPOSITION, CURABLE COMPOSITION, AND MOLDED BODY - A method of manufacturing a monomer composition includes a step of mixing a zinc catalyst (A), an iso(thio)cyanate compound (B) having an iso(thio)cyanate group, and an alcohol compound (C) having a hydroxy group, and at least one of the iso(thio)cyanate compound (B) or the alcohol compound (C) has a (meth)acryloyl group. | 2022-08-11 |
20220249332 | TREATMENT METHODS FOR MEDICAL AND DENTAL IMPLANTS, PERIODONTAL DISEASES AND MEDICAL PROCEDURES - Dental and medical treatments and methods, including treating gum disease, using peroxide gel and a viscous antimicrobial including a topical antibacterial agent, a topical antiviral agent, a topical antibiotic, a topical antifungal agent, a topical antiseptic agent, or a topical anti-intermicrobial agent to chemically debride and curettage a treatment area. Treatments and methods include non-surgically scaling and root plaining the treatment area with dental tools such as periodontal scalers and/or curettes during the active period of the chemical debridement. The working surfaces of dental and medical tools can be sharpened for optimal root and tooth surfacing during treatment. Treatment can include instructions for co-therapy by or on behalf of treatment subjects between visits and for maintenance care. | 2022-08-11 |
20220249333 | HYDROPHILIZED INORGANIC POWDER AND COSMETIC INCLUDING HYDROPHILIZED INORGANIC POWDER - Provided are: a hydrophilized inorganic powder having favorable properties while reducing the blending amount of a surfactant; and a cosmetic including the hydrophilized inorganic powder. A hydrophilized inorganic powder including an inorganic powder as a base material, a hydrophobic coat that covers the surface of the inorganic powder, and a hydrophilic coat that covers the hydrophobic coat, wherein the composition of the hydrophilic coat is a nonionic surfactant(s) having a hydrophilic moiety and a carbon chain moiety, and has a branched structure sufficient for imparting self-dispersibility in the carbon chain moiety is provided. | 2022-08-11 |
20220249334 | Moisturizer Sheets - This present invention relates to a pre-packaged set of oil infused moisturizer sheets that can be used to transfer the oils to a selected area of the body. The moisturizer sheets are infused with different types of oils such as castor oil, almond oil, essential oils, coconut oil, and more. The sheets can be applied multiple times a day to help moisturize user's skin and can be stored in a protective storage case to keep the sheets fresh while offering a simple and convenient method for transporting the sheets. The protective storage case is reusable and can be refilled with a replenishment set of infused moisturizer sheets. | 2022-08-11 |
20220249335 | COMPOSITIONS FOR IMPARTING COLOR AND TONE TO THE HAIR - The disclosure relates to foaming hair compositions, kits and devices comprising the compositions, and methods of use thereof. The foaming hair compositions comprise an emulsifier system, at least one amphoteric surfactant, quaternium-80, at least one direct dye or pigment, and water. | 2022-08-11 |
20220249336 | WATER-IN-OIL EMULSION COMPOSITION - The present invention provides a water-in-oil emulsion composition having a high water occlusive of a coating film and having good skin protective feeling and glossiness. The water-in-oil emulsion composition is provided containing the following components (A), (B), (C), (D) and (E): (A) 1% by mass or more and 15% by mass or less of a lipophilic surfactant having an HLB of 2-6; (B) 0.15% by mass or more and 8% by mass or less of a dextrin fatty acid ester having 8-22 carbon atoms in the fatty acid moiety; (C) 1% by mass or more and 20% by mass or less of one or more oily components selected from a dimer acid ester, a fatty acid cholesterol ester having 16-22 carbon atoms, a fatty acid phytosterol ester having 16-22 carbon atoms, and an N-acyl amino acid ester; (D) a hydrocarbon oil that is liquid at 25° C.; and (E) water. | 2022-08-11 |
20220249337 | CORE-SHELL PCM MICROCAPSULE HAVING AUTOMATIC TEMPERATURE CONTROL FUNCTION AND COOLING COSMETIC COMPOSITION FOR EXTERNAL SKIN INCLUDING THE SAME - Provided are preparation of a PCM microcapsule in the form of a core-shell having an excellent heat absorption function by using a temperature-controllable phase change material (PCM) as a core material and a biodegradable polymer material as a shell material, and a cooling cosmetic composition for external skin capable of exhibiting a prevention effect of thermal aging using the same. The core-shell PCM microcapsule having an automatic temperature control function according to the present invention is prepared by dissolving a shell material and a single or mixed PCM in a solvent to produce an oil phase polymer solution, dissolving an aqueous polymer to produce an external continuous phase, emulsifying the oil phase polymer solution and the external continuous phase, and removing the external continuous phase and the solvent and carrying out drying. | 2022-08-11 |
20220249338 | Oral Care Article Comprising a Hydrophobic Delivery Carrier and Solid Hydrophilic Particle Comprising a Bleaching Agent - An oral care article in form of a strip for use in the oral cavity. The oral care article includes a hydrophobic delivery carrier comprising embedded solid hydrophilic particles comprising at least one bleaching agent, wherein at least about 20 parts by weight of the particles dissolve in about 100 parts by weight of water and/or the particles increase in volume and/or weight by at least about 50% upon contact with water. | 2022-08-11 |
20220249339 | METHOD FOR SUPPRESSING ATTACHMENT OF AIR POLLUTANTS - Disclosed are: a method for suppressing adhesion of air harmful substances, including applying a metal oxide (A) having an average primary particle diameter d | 2022-08-11 |
20220249340 | ORAL COMPOSITIONS AND METHODS OF USE - Compositions that include: from 5 wt-% to 70 wt-% of one or more plant based oils based on the total weight of the composition; from 35 wt-% to 95 wt-% of an aqueous phase based on the total weight of the composition; not greater than 7.5 wt-% of one or more surfactants based on the total weight of the composition; and not greater than 3 wt-% of a viscosity modifier of, wherein the composition has a pH from 4.5 to 9.5, the composition is an oil in water (o/w) emulsion, and the composition is edible. Methods of utilizing disclosed compositions are also included. | 2022-08-11 |
20220249341 | CLEANSING COMPOSITION PROVIDING ENHANCED DEPOSITION OF SALICYLIC ACID FOR ACNE TREATMENT - A cosmetic composition for treating acne includes at least one acne treatment active that includes at least one beta hydroxy acid and an aqueous carrier comprising at least one cationic polymer. In some embodiments the cosmetic composition is a cleanser that comprises at least one surfactant. When the composition is applied to a keratinous tissue it demonstrates deposition and retention of the beta hydroxy acid on the keratinous tissue after rinsing with water in an amount representing about at least 60% and up to about 250% greater as compared with an amount deposited using a composition that lacks the at least one cationic polymer. | 2022-08-11 |
20220249342 | COSMETIC CLEANSING COMPOSITIONS WITH VISCOSITY MODIFIERS AND OILS - A cosmetic cleansing composition includes a cosmetic carrier system, and a cleansing coagulant system that includes at least one of each of an oil and a viscosity modifier, the viscosity modifier selected from synthetic (including petrochemical based) and natural polymers. The coagulant system can congeal and form a viscoelastic fluid to bind and remove sebum, makeup, dirt, pollution, dead skin and other unwanted material from skin. | 2022-08-11 |
20220249343 | COSMETIC COMPOSITION INCLUDING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE, AND TOPICAL USE THEREOF - The present invention relates to a composition comprising: a 5-benzyl aminosalicylic acid compound in chemical formula I or cosmetically acceptable salts thereof; and a cosmetically acceptable excipient suitable for local administration. The composition comprising the 5-benzyl aminosalicylic acid compound in chemical formula I or cosmetically acceptable salts thereof can be used for reducing or alleviating human skin aging by means of antioxidant, anti-inflammatory and whitening actions on the skin. | 2022-08-11 |
20220249344 | PERSONAL CARE COMPOSITIONS WITH CYSTINE - Personal care topical compositions at skin-tolerant pH with cystine which is solubilized or has small crystal size below 20 microns. A process of making the composition is also described. | 2022-08-11 |
20220249345 | PRODUCT FOR TREATING KERATINOUS FIBERS, CONTAINING SILANES OF SPECIFIC FORMULAE - A cosmetic composition for the treatment of keratinous material, in particular keratinous fibers, includes
| 2022-08-11 |
20220249346 | STABILIZED POLYRIBONUCLEOTIDE CODING FOR AN ELASTIC FIBROUS PROTEIN - The invention relates to a polyribonucleotide, a cosmetic and pharmaceutical compound that has the polyribonucleotide and a medicinal product that has the polyribonucleotide and the compound. | 2022-08-11 |
20220249347 | Composition and Method Containing Pea and Quinoa Natural Peptides And Niacinamide to Enhance Skin Glow, Radiance And Even Skin Tone - Healthy glow is characterized by radiant skin, brighter, lighter, even skin tone and clear skin without blemishes. Skin pigmentation is a process known as melanogenesis involving production, transportation, and distribution of melanin from the epidermis's inner layer to the skin's surface. There are multiple biological processes and underlying gene pathways that impact overall melanogenesis. Disclosed is a composition and methods for a combination of Vitamin B3 and Pea and Quinoa peptides obtained from hydrolyzed proteins. This composition was found to offer a holistic approach to the skin glow through multi targeted action controlling key biological pathways. Vitamin B3, Pea peptides, and Quinoa peptides were found to deliver a synergistic effect for desired skin glow, radiance, even skin tone, uniformity, homogeneity, smoothing skin texture, reducing dark spots/hyperpigmentation and improve skin appearance without any reported side effects as compared to formulations without the composition. | 2022-08-11 |
20220249348 | METHODS FOR TREATING CELLULITE - The invention relates to the discovery that collagenase injections are effective in dissolving and lysing the collagenase septa network in the skin that comprises cellulite. As such, the invention relates to methods of treating cellulite in a patient in need of such treatment comprising injecting or otherwise delivering the effective amount of purified collagenase to the collagenase septa network of cellulite in the skin. The invention also relates to the use of collagenase in the manufacture of a medicament to treat cellulite of the skin. | 2022-08-11 |
20220249349 | MOISTURIZING COMPOSITIONS AND USES THEREOF - Embodiments herein are directed to moisturizing compositions comprising interpenetrating polymer networks, methods of making moisturizing compositions and methods of using moisturizing compositions. | 2022-08-11 |
20220249350 | COMPOSITION FOR AEROSOL COSMETICS, AND AEROSOL COSMETICS - The objective of the present invention is to provide a composition for aerosol cosmetics employed for producing aerosol cosmetics which easily render the formulation design, have improved dispensability, and stably make a foam with greater foam quality. The objective is achieved by a composition for aerosol cosmetics, comprising hydroxypropyl methylcellulose, an organic solvent and water, wherein a ratio of interfacial elastic modulus (E′) to interfacial viscous modulus (E″) of the hydroxypropyl methylcellulose is equal to or higher than 5.0 when measured with a tensiometer at 25° C. using a 0.2% by mass aqueous solution, and the like. | 2022-08-11 |
20220249351 | COSMETIC - Provided is a cosmetic containing a composite particle containing a starch alkenyl succinate metal salt coated with 0.05 to 2 parts by mass of zinc oxide to 1 part by mass of the starch alkenyl succinate metal salt. The starch alkenyl succinate metal salt may be at least one selected from the group consisting of a starch octenyl succinate metal salt, a starch decenyl succinate metal salt, a starch dodecenyl succinate metal salt, a starch tetradecenyl succinate metal salt, a starch hexadecenyl succinate metal salt, and a starch octadecenyl succinate metal salt. | 2022-08-11 |
20220249352 | MICROPARTICLES BASED ON ESTER DERIVATIVES OF HYALURONAN, METHOD OF PRODUCTION, COMPOSITION COMPRISING THEREOF AND USE THEREOF - Microparticles based on ester derivatives of hyaluronan and related methods and compositions are disclosed. The microparticles comprise a conjugate of all-trans retinoic acid and a particular hyaluronan comprising from 1 to 5000 dimer units; where the microparticles comprise a degree of substitution of all-trans retinoic acid residues in the conjugate of hyaluronan in the range of from 0.1 to 8%. Methods of preparing the microparticles and related compositions are also disclosed. | 2022-08-11 |
20220249353 | COSMETIC COMPOSITION COMPRISING ANIONIC AND AMPHOTERIC SURFACTANTS, CATIONIC POLYSACCHARIDES AND UNSATURATED FATTY ALCOHOLS, AND COSMETIC TREATMENT PROCESS - The present invention relates to a cosmetic composition, notably a hair composition, comprising anionic surfactants, amphoteric surfactants, cationic polysaccharides and unsaturated fatty alcohols present in a content of less than 1% by weight relative to the total weight of the composition. The invention also relates to a cosmetic treatment process for caring for and/or cleansing the hair, using said composition. | 2022-08-11 |
20220249354 | WATER BASED COMPOSITION - To provide a water based composition having an appropriate level of viscosity, which does not impart a sensation of stickiness, corrects unevenness such as pores, and has long lasting cosmetic effects. A water based composition includes an (A) crosslinked siloxane elastomer, a (B) lipophilic porous powder, and a (C) aqueous medium. | 2022-08-11 |
20220249355 | COSMETIC CARE METHOD BASED ON PHOTOACTIVE EXTRACTS OF MICROALGAE - The present invention concerns a cosmetic care method for the skin comprising the steps of applying, to the skin, a cosmetic composition comprising photoactive extracts of at least one microalgae, and exposing the area to which the composition has been applied to light. The invention also comprises a device for cosmetic care according to the method, and a kit comprising a cosmetic composition comprising photoactive extracts of at least one microalgae and a lighting device according to the invention. The invention finally comprises the use of the device according to the invention for an anti-aging and/or anti-wrinkle treatment and/or a treatment promoting the healing of the skin area. | 2022-08-11 |
20220249356 | Natural Shampoo with Buchu - A natural viscous liquid shampoo including a composition formulated with buchu extract and a preparation method thereof that would be harmless to the hair and scalp. The natural shampoo was created without sulphates and/or harmful chemicals and still cleanse your scalp but also balance your natural oils and promote healthier hair growth. | 2022-08-11 |
20220249357 | OIL EXTRACT FROM GARDENIA JASMINOIDES FLOWERS AND COSMETIC COMPOSITIONS COMPRISING IT - An oil extract from | 2022-08-11 |
20220249358 | METHOD FOR OBTAINING BIOACTIVE INGREDIENTS, USE OF SUBCRITICAL-WATER EXTRACTION PROCESS, BIOACTIVE INGREDIENT, USE OF BIOACTIVE INGREDIENT AND COSMETIC COMPOSITION - The present invention relates to a method for obtaining single-use bioactive ingredients using a specific extraction process and new bioactive ingredients from renewable sources, in particular from the Amazon region, that can be used to prepare cosmetic compositions for treating skin, hair and/or scalp. Said bioactive ingredients are obtained by means of a subcritical-water extraction process parameterized to obtain bioactive compounds from different species and different plant components. | 2022-08-11 |
20220249359 | COSMETIC COMPOSITIONS AND METHODS FOR THEIR USE IN FIRMING SKIN - A method of reducing the appearance of loose, sagging, or flaccid skin is disclosed. The method can include topically applying to skin in need thereof a composition that includes 0.0001 wt. % to 10 wt. % | 2022-08-11 |
20220249360 | Dedifferentiated cell extract of Bletilla and method for whitening, anti-oxidation and anti-wrinkling applying the same, and cosmetic comprising the same - The present invention provides a | 2022-08-11 |
20220249361 | COSMETIC COMPOSITION COMPRISING A BIFIDOBACTERIUM SPECIES LYSATE, AN EXTRACT OF YEAST OF THE SACCHAROMYCES GENUS, AND A MONOSACCHARIDE AND COSMETIC USES THEREOF - The present invention relates to a cosmetic composition comprising, in a physiologically acceptable medium: —at least one microorganism of the | 2022-08-11 |
20220249362 | NOVEL LEVOTHYROXINE FORMULATIONS FOR ORAL USE - The present invention relates to novel oral spray formulations of Levothyroxine. Further the invention also describes process for preparing such formulations. | 2022-08-11 |
20220249363 | AUGMENTATION OF PERSONALIZED TUMOR SPECIFIC ADAPTIVE IMMUNITY THROUGH EXTRACORPOREAL REMOVAL OF IMMUNE BLOCKING FACTORS - Disclosed are means, methods and compositions of matter useful for amplification of adaptive immune responses towards neoplastic tissue. In one embodiment, immunization of a patient is performed by a means comprising of administering either an exogenous vaccine or stimulation of immunogenicity of the tumor so as to cause release of antigens/increased exposure of antigens, thus resulting in an “endogenous” vaccine. Subsequent to vaccination a patient is treated by an immunopheresis procedure, in order to allow for removal of “blocking factors” produced by the tumor or produced by cells programmed by tumors to produce said blocking factors. In one embodiment further immunization is performed subsequent to removal of said blocking factors in order to allow for enhancement of adaptive immune responses. | 2022-08-11 |
20220249364 | Designed Inhibitors of Tight Junction Formation - The present invention relates to isolated peptides suitable for disrupting an epithelial barrier, transepithelial dmg or vaccine formulations, drug delivery vehicles for delivering these formulations, and methods of using of these formulations for disrupting an epithelial barrier. | 2022-08-11 |
20220249365 | BIOERODIBLE IMPLANT FOR LONG-TERM DRUG DELIVERY AND ASSOCIATED METHODS OF MANUFACTURE AND USE - A drug delivery system is provided in the form of a controlled release, bioerodible pellet for subdermal implantation. The pellet is bioerodible, and provides for the sustained release of a pharmacologically active agent over an extended time period. As such, the drug delivery system finds significant utility in chronic drug administration. Bioerosion products are water soluble, bioresorbed, or both, obviating the need for surgical removal of the implant. Methods for manufacturing and using the drug delivery system are also provided. | 2022-08-11 |
20220249366 | THIOL-MICHAEL ADDITION HYDROGEL-BASED BRACHYTHERAPY SYSTEM AND METHODS COMPRISING THE SAME - The invention relates generally to methods of using a thiol-Michael addition hydrogel for providing intracavitary brachytherapy and/or displacing tissue and organs. The thiol-Michael addition hydrogel may be used as a packing material and an attenuation material for intracavitary brachytherapy applications. The invention also relates generally to a brachytherapy applicator, which may be used in conjunction with the thiol-Michael addition hydrogel and methods thereof. The invention also relates to a positioning device system for providing intracavitary brachytherapy treatment and a kit thereof. | 2022-08-11 |
20220249367 | STEROIDAL COMPOSITIONS AND METHOD OF MAKING AND USE - Disclosed herein are compositions suitable for use in increasing the energy level, memory function and cognitive focus, and lowering the feeling of lethargy in men and women. Further disclosed are methods of use and processes for preparing the disclosed compositions. | 2022-08-11 |
20220249368 | HEAT RESISTANT CHEWABLE ORAL FORM WITH AN AGAR MATRIX AND MANUFACTURING PROCESS THEREOF - The present invention defines a process for forming a chewable oral dosage form, such as a gum having a pleasant flavor and texture. In particular, the invention includes a process of forming an oral dosage form, comprising: a first step of hydrating a gelling agent of agar-agar and locust bean gum; a second step of mixing in components of the agar matrix; a third step of mixing in an active ingredient; a fourth step of cooking the mixture; a fifth step of flavoring; a sixth step of moulding and gelling; and a seventh step of demoulding, degreasing and drying. The oral dosage form according to the invention also comprises an agar-agar matrix combined with gums, such as locust bean gum, and/or sugar; glycerol; inulin; flavoring agents; citric acid; a coating; and water, to complete the composition, which includes active ingredients. | 2022-08-11 |
20220249369 | BIOLOGICAL BITS AS COMPUTABLE ELEMENTS WITHIN LIVING SYSTEMS - Disclosed herein are protease-based biological circuits for use in the diagnosis and treatment of disease and disorders characterized by aberrant protease signaling. An exemplary method of treating disease in a subject includes administering to the subject a plurality of therapeutic agent loaded-liposomes, wherein each of the liposomes comprises a different density of peptides surrounding the core and a different dose of the therapeutic agent, wherein the peptides comprise a cleavage site for a protease of interest, and wherein cleavage of the peptides open the liposome and release the therapeutic agent from within the liposome. | 2022-08-11 |
20220249370 | NANO-MICELLE PREPARATION OF ICARITIN AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF - A nano-micelle preparation of icaritin. The preparation comprises icaritin and polymer auxiliary materials. Further provided is a preparation method for the nano-micelle preparation, and the prepared nano-micelle preparation of icaritin has the advantage of high bioavailability. | 2022-08-11 |
20220249371 | Extended Release Vitamin C and Manufacturing Thereof - The present disclosure is directed to an extended release composition containing Vitamin C in a lipid matrix, which releases the Vitamin C over a period of time. | 2022-08-11 |
20220249372 | Lipid Particle Formulations for Delivery of RNA and Water-Soluble Therapeutically Effective Compounds to a Target Cell - The present invention relates to lipid particles comprising at least one cationic lipid, at least one water-soluble therapeutically effective compound and RNA. Further, the present invention relates to a pharmaceutical composition comprising such particles. Said pharmaceutical composition is useful for inducing an immune response. It is also useful in a prophylactic and/or therapeutic treatment of a disease involving an antigen. Furthermore, the present invention relates to a method for producing the particles. | 2022-08-11 |
20220249373 | MEMBRANE PROTEIN SCAFFOLDS FOR EXOSOME ENGINEERING - The present disclosure relates to heterologous exosomal vesicle proteins (HEVPs), engineered exosomes comprising HEVPs, and methods of preparing and using these compositions, including therapeutic applications. | 2022-08-11 |
20220249374 | RADIOTHERAPEUTIC MICROSPHERES - Certain embodiments are directed to compositions comprising and method for producing alginate microspheres that contain liposomes encapsulating a variety of useful substances. Substances of note that can be encapsulated in liposomes and loaded alginate microspheres include radiotherapeutics (e.g., rhenium-188), radiolabels (e.g., technetium-99m), chemotherapeutics (doxorubicin), magnetic particles (e.g., 10 m iron nanoparticles), and radio-opaque material (e.g., iodine contrast). | 2022-08-11 |
20220249375 | SUSTAINED-RELEASE LIPID COMPOSITION AND PREPARATION METHOD THEREFOR - Disclosed are a sustained-release lipid composition and a preparation method therefore. Specifically, the present invention relates to a solid composition containing lipids and a liposome composition obtained therefrom, wherein the liposomes have improved release properties. | 2022-08-11 |
20220249376 | NANOVESICLES AND ITS USE FOR NUCLEIC ACID DELIVERY - The present invention refers to a nanovesicle comprising a sterol and a non-lipid cationic surfactant, for example myristalkonium chloride, wherein the sterol comprises DC-cholesterol. It also refers to a pharmaceutical composition that comprises it and its uses as a delivery system and as a bioimaging and theranostic tool. Furthermore, it also refers to the nanovesicle or the pharmaceutical composition for use as a medicament, in particular for use in the treatment of cancer. | 2022-08-11 |
20220249377 | EXTENDED RELEASE COMPOSITIONS COMPRISING TRIHEXYPHENIDYL - The present disclosure provides extended release trihexyphenidyl compositions suitable for once- or twice-daily administration. The compositions comprise a core comprising at least one organic acid; at least one drug layer comprising trihexyphenidyl or a pharmaceutically acceptable salt thereof over the core; and a functional coat over the drug-layered core. The compositions of the disclosure provide extended release with reduced C | 2022-08-11 |
20220249378 | METHOD FOR FREEZE-DRYING CELLS IN A HYDROGEL COMPRISING NANOFIBRILLAR CELLULOSE AND FREEZE-DRIED CELLS IN AN AEROGEL COMPRISING NANOFIBRILLAR CELLULOSE - The present disclosure provides a method for freeze-drying cells in a hydrogel comprising nanofibrillar cellulose, the method comprising providing a hydrogel comprising nanofibrillar cellulose, providing cells, combining the cells and the hydrogel comprising nanofibrillar cellulose to form a cell system, and freeze drying the cell system to obtain dried cells in a hydrogel comprising nanofibrillar cellulose. The present disclosure also provides a freeze-dried hydrogel comprising nanofibrillar cellulose and cells. | 2022-08-11 |
20220249379 | SOLID DOSE FORMULATIONS FOR NEEDLE-FREE DELIVERY - The present disclosure relates to solid dose formulations for needle-free delivery comprising 0.01 to 60 (w/w) of one or more therapeutic agent and/or prophylactic agent; and 40.0% to 99.99% (w/w) of dextran. The invention further concerns methods of producing a solid dose formulation tablet and application its particular medical uses, in particular as a vaccine. | 2022-08-11 |
20220249380 | PHARMACEUTICAL COMPOSITIONS COMPRISING GRANULATED BEMPEDOIC ACID - Herein disclosed are novel compositions comprising: Bempedoic acid and Bempedoic acid and Ezetimibe, kits, methods of using and processes for making said novel compositions. Notably, the formulations herein provide pharmaceutical compositions having excellent stability and release properties for both drug products. These improved formulations are useful in the treatment and prevention of cardiovascular disease. | 2022-08-11 |
20220249381 | COMPRESSED MACITENTAN COMPOSITIONS, METHODS AND USES THEREOF - The present disclosure also relates to compressed compositions comprising a therapeutically effective amount of macitentan, a sugar alcohol diluent and a surfactant. It also relates to the process of obtaining said compressed compositions, oral pharmaceutical compositions comprising them, and their use in the treatment of pulmonary arterial hypertension. | 2022-08-11 |
20220249382 | COMPOSITIONS COMPRISING INDIGO AND/OR AN INDIGO DERIVATIVE AND METHODS OF USE THEREOF - Compositions comprising an AhR agonist compound, such as indigo and/or an indigo derivative, such as indirubin and isatin, are described. Methods of treatment, including the treatment of ulcerative colitis, by administering the compositions are described. In an embodiment, compositions in the form of a solid amorphous dispersion of the AhR agonist are described. | 2022-08-11 |
20220249383 | TABLETING OF SPECIFIC POLYMER STABILIZERS - The present disclosure relates to a method for manufacturing a tablet including
| 2022-08-11 |
20220249384 | Systems and Methods for Troche Production - A troche/rapidly dissolving tablet production system includes a temperature-controlled heating plate, a score plate configured to confront said heating plate, and a cavity plate configured to confront said scoring plate, said cavity plate comprising a plurality of cavities. | 2022-08-11 |
20220249385 | EXTENDED RELEASE COMPOSITION OF TOFACITINIB - The present disclosure provides an extended release composition of tofacitinib for oral administration, and methods of making the composition. The extended release composition employs a matrix drug core comprising tofacitinib or a pharmaceutically acceptable salt thereof and at least one release controlling polymer. The matrix drug core is surrounded by a soluble functional coating comprising at least one coating polymer and at least one pharmaceutically acceptable excipient. | 2022-08-11 |
20220249386 | DRUG DELIVERY COMPOSITION - There is provided a drug delivery composition containing an acid-resistant cell that encloses a drug in the cell. In addition, there is provided an acid-resistant cell in which a drug is enclosed in the cell, where the drug is localized in the sac-shaped membrane structure included in the acid-resistant. | 2022-08-11 |
20220249387 | POLYMER PROTEIN MICROPARTICLES - Microparticles containing a core of therapeutic protein and a cortex of a biocompatible and biodegradable polymer, and methods of making and using the microparticles are provided. The extended release of a therapeutic protein from the microparticles in a physiological solution is demonstrated over an extended period of time. | 2022-08-11 |
20220249388 | NANOPARTICLES COMPRISING ENZALUTAMIDE - The invention relates to nanoparticles comprising Enzalutamide, processes for the preparation of such nanoparticles, pharmaceutical compositions and pharmaceutical dosage forms comprising such nanoparticles, processes for the preparation of such pharmaceutical dosage forms, and uses of the pharmaceutical dosage forms for medical purposes. | 2022-08-11 |
20220249389 | IMMUNOTHERAPEUTIC CONSTRUCTS AND METHODS OF THEIR USE - Disclosed herein are immunotherapeutic constructs comprising a delivery particle, at least one adjuvant, and one or more therapeutic agents/compounds that cause antigen release and/or modulate immunosuppressive tumor microenvironment. These immunotherapeutic constructs create adaptive immunity or anti-cancer immune response(s) that can be used, for instance, to prevent and treat broad types of cancer. Further disclosed are uses of the immunotherapeutic constructs, including to prevent and treat cancer in humans and animals. | 2022-08-11 |
20220249390 | DELAYED DELIVERY OF ANTICANCER DRUGS - The present invention relates to an anti-cancer delivery system with a delayed release of one or more chemotherapeutic agent(s), a mixture for use in the treatment of cancer comprising such a delivery system and a method for producing such a delivery system. | 2022-08-11 |
20220249391 | THERAPEUTIC POTENTIAL OF CELLULOSE-CYCLODEXTRIN-CURCUMIN NANOCRYSTALS IN THE TREATMENT OF PERIPHERAL NEUROPATHIES - Disclosed is a complex including: cellulose nanocrystals; at least one β-cyclodextrin molecule; and at least one curcumin molecule, suitable for use in the treatment of any kind of peripheral neuropathies. Further disclosed is a pharmaceutical composition including at least the complex and at least one pharmaceutically acceptable excipient. Also disclosed is the use of the complex or the pharmaceutical composition, in particular in the form of a hydrogel, a subcutaneous implant, an implantable pump, an implanted biofunctionalized nerve conduit, to improve the treatment compliance, to allow an extended release of the complex and to obtain better pharmacokinetics. | 2022-08-11 |