33rd week of 2021 patent applcation highlights part 41 |
Patent application number | Title | Published |
20210255136 | Microfabricated Electrochemical Gas Sensor - This invention describes an electrochemical gas sensor that utilizes microfabrication to achieve miniaturization without using a membrane. The sensor is comprised of thin film electrodes and insulators, and micro cavities in them. The micro cavities are filled with a liquid electrolyte that is kept in the micro cavities by surface tension. | 2021-08-19 |
20210255137 | GAS SENSOR - A gas sensor includes a sensor element including a solid electrolyte, a gas chamber, a pump electrode, a sensor electrode, and a reference electrode. The pump electrode and sensor electrode are provided in the solid electrolyte in a state in which the pump electrode and the sensor electrode are housed in the gas chamber. The reference electrode is provided in the solid electrolyte. The pump electrode and the sensor electrode contain Au. Au content in a surface layer is equal to or greater than 1 mass % and higher than Au content in a reference layer. The surface layer is an area from a surface of the sensor electrode to a depth of 0.3 nanometers. The reference layer is an area extending to a depth of 2 or more to 3 or less nanometers from the surface of the sensor electrode. | 2021-08-19 |
20210255138 | Method and Device for Determining the Ammonia Concentration and the Nitrogen Monoxide Concentration in the Exhaust Gas Flow of a Motor Vehicle - Various embodiments include a method of ascertaining the ammonia concentration and the nitrogen monoxide concentration in the exhaust gas stream from a motor vehicle comprising: measuring a pumping current at least three times; and determining an ammonia concentration and a nitrogen monoxide concentration based on three successive pumping current measurements. | 2021-08-19 |
20210255139 | GAS SENSOR - The gas sensor according to an exemplary embodiment of the present invention comprises: an FET device including one or more gate electrodes; a sensor array part including a plurality of sensors, in which a first electrode of each sensor is connected to at least one gate electrode of the plurality of gate electrodes in the FET device; and a controller detecting a gas using a current between a drain-source in response to voltage changes in the gate electrode of the FET device, wherein each sensor includes: a first electrode connected to a gate electrode of the FET device; a second electrode receiving an operating voltage through a switch controlled by the controller; and a detection film interposed between the first electrode and the second electrode. | 2021-08-19 |
20210255140 | FLUIDIC STACK AND REFERENCE ELECTRODE FOR SAMPLE COLLECTION AND ANALYSIS AND RELATED METHODS - Some embodiments relate to a device with a fluidic stack that includes a filter, a fluidic block adjacent to the filter that includes a first channel through the fluidic block, a first layer adjacent to the fluidic block that includes at least a portion of a second channel that is in fluid communication with the first channel, and a sensor adjacent to the first layer and in fluid communication with the second channel. The device can include a fluid reservoir that includes one or more dimensions of the second channel and/or the sensor, and a reference electrode disposed within the fluid reservoir. | 2021-08-19 |
20210255141 | ELECTROSEPARATION SYRINGE AND ANALYTICAL PROCESSES USING THE ELECTROSEPARATION SYRINGE - The present application relates to processes for modifying the distribution of a compound in a solution comprising drawing the solution comprising the compound into an electroseparation syringe comprising a syringe barrel, a plunger and electrodes positioned to apply a voltage across solution contained in the syringe barrel, and applying a voltage across the solution in the syringe barrel to modify the distribution of the compound within the solution contained in the syringe barrel. The process may be performed as a part of an analytical process. Also described is an electroseparation syringe for performing such processes, and an apparatus for analysing a sample, the apparatus comprising: —an electroseparation syringe comprising a syringe barrel, a plunger and a pair of electrodes positioned to enable a voltage to be applied across any liquid contained within the syringe barrel, or a receiver for receiving an electroseparation syringe; —a power supply for supplying a voltage potential; —a plunger controller for operation of the plunger to draw up and dispense liquid into the syringe barrel; —an analyser for analysing liquid delivered to the analyser; —a sample reservoir for holding solution to be subjected to analysis; —a valve in fluid connection with the electroseparation syringe that enables fluid flow between the electroseparation syringe and the analyser and fluid flow between the electroseparation syringe and the sample reservoir; and —a controller for controlling operation of the power supply to the electrodes, operation of the plunger to draw liquids into the syringe barrel and dispense liquids from the syringe barrel, and to control the valve setting for controlling the direction of fluid flow. | 2021-08-19 |
20210255142 | DIAGNOSING APPARATUS, ANALYSIS METHOD, AND PROGRAM - [Object] An object of the present technology to provide a diagnosing apparatus capable of providing, more accurately and simply, information for determining at least one item selected from the group consisting of a type of an illness that has developed in a subject, and a state of progress of the illness that has developed in the subject. Another object of the present technology is to provide an analysis method. | 2021-08-19 |
20210255143 | DEVICE AND METHOD FOR MAGNETICALLY DETECTING MICROSCOPIC BIOLOGICAL OBJECTS - A device for magnetically detecting microscopic biological objects includes a microfluidic channel having a fluid inlet and a fluid outlet; a plurality of magnetic sensors arranged against an inner wall of the microfluidic channel; and a permanent magnet arranged against an outer wall of the microfluidic channel, in such a way that the plurality of magnetic sensors is immersed in a magnetic field created by the permanent magnet; the plurality of magnetic sensors including a first magnetic sensor; a second magnetic sensor opposite the first magnetic sensor; a third magnetic sensor downstream of the first and second magnetic sensors. | 2021-08-19 |
20210255144 | Acoustic resonance chamber - A system for determining gas characteristics at high altitudes in embodiments of the present invention may have one or more of the following features: (a) a high-altitude balloon having one or more of the following features: (a) a balloon, (b) a balloonsat operably coupled to the balloon, (c) an air path chamber wherein gas at a high altitude can occupy the air path chamber, (d) a first speaker located on a substrate within the air path chamber, wherein the first speaker takes an electrical signal input and creates a first sound wave, and (e) a second speaker located on the substrate facing opposite of the first speaker located outside of the air path chamber, wherein the second speaker takes the electrical signal and creates a second sound wave. | 2021-08-19 |
20210255145 | SYSTEM FOR INSPECTING A REPAIR OR JOINT CONSISTING OF A COMPOSITE MATERIAL APPLIED TO A STRUCTURE - This invention relates to inspection techniques for use on composite joints and repairs. In this context, this invention proposes a system for inspecting a repair or joint consisting of a composite material applied to a structure, comprising at least one exciter or element that is excitable ( | 2021-08-19 |
20210255146 | DEVICE AND METHOD FOR DETERMINING THE EXTENT OF DEFECTS BY MEANS OF V THROUGH-TRANSMISSION - Method is provided for determining the extent of defects, in particular of crack depths, in a test specimen. At least one transmitting transducer excites sound waves in the ultrasonic range, and the sound waves propagate in the form of a sound beam. The acoustic axis of the sound beam preferably forms an angle the normal to a surface of the test specimen facing the transmitting transducer. The sound waves couple into the test specimen obliquely and are reflected in particular in a V-shaped manner at a preferably outer interface of the test specimen. At least one receiving transducer spaced apart from the transmitting transducer receives the sound waves reflected at the interface of the test specimen. By means of an evaluation unit, an extent of a defect arranged within a sound path is determined from a reduction of the amplitude of the sound waves received by the receiving transducer. The transmitting transducer and the receiving transducer are guided past the test specimen at an at least substantially constant distance therefrom, and the sound waves are coupled into the test specimen with an advance section via a liquid medium. A device for detecting signals based on defects in a test specimen is also provided. | 2021-08-19 |
20210255147 | SENSOR ARRANGEMENT, USE OF THE SENSOR ARRANGEMENT AND METHOD FOR DETECTING STRUCTURE-BORNE NOISE - Method for detecting structure-borne sound, comprising the following steps: attaching a structure-borne sound sensor ( | 2021-08-19 |
20210255148 | LASER SYSTEM FOR BLOOD OR TISSUE ASSESSMENT - A laser system for blood assessment is provided. Another aspect of a laser system includes a container within which is blood, a laser operable to emit a laser beam at the container to vibrate the blood, a detector operable to detect a vibrational characteristic of the blood, a controller connected to the detector operable to automatically determine a characteristic of the blood based at least in part on the vibrational characteristic detected by the detector, and a display operable to indicate a determination result from the controller. Another aspect of the present blood or tissue assessment laser system includes a laser, a power supply, a detector, a controller and an electronic display, all contained within or coupled to a handheld and portable housing. | 2021-08-19 |
20210255149 | ULTRASONIC PROBE AND METHOD OF MANUFACTURING THE SAME - Disclosed are an ultrasonic probe and a method of manufacturing the same. The ultrasonic probe includes a piezoelectric layer including one or more kerfs such that piezoelectric elements are provided in a plurality of rows along an elevation direction, a first electrode formed on an upper side of the piezoelectric layer, a second electrode formed on a lower side of the piezoelectric layer, a matching layer disposed above the piezoelectric layer and including one or more grooves connected to the one or more kerfs, and a third electrode formed in inner surfaces of the one or more grooves and electrically connected to the first electrode. | 2021-08-19 |
20210255150 | DEVICE FOR EXAMINING THE INTERIOR OF A PIPE USING MULTI-ELEMENT ULTRASOUND - A device for examining the interior of a pipe using multi-element ultrasound technology, finding application in the detection of defects in the wall of a tubular pipe or the verification of the characteristics of the wall of a tubular pipe is disclosed. The device is designed to be placed inside a fluid transport pipe and to move under the action of the transported fluid, to detect defects in, or check characteristics of, the wall of the pipe. The device has a circumference and comprises a plurality of ultrasonic sensors distributed over its circumference and each formed by a plurality of transmitters and a plurality of reception antennas. The device also includes an electronic controller configured to control each sensor and to receive and record the information measured by the sensors. | 2021-08-19 |
20210255151 | DETECTING MATERIAL TYPE USING LOW-ENERGY SENSING - A system and method for detecting material type using low-energy sensing are disclosed. The method includes receiving frequency words from a tag attached to a container containing material, wherein the tag provides a low-energy sensing configured to transmit the frequency words; extracting at least a first data feature from the received frequency words, wherein the first data feature changes in response to a type of material in the container; classifying the extracted data feature to label a type of the material in the container; and sending a notification indicating the type of material in the container. | 2021-08-19 |
20210255152 | SIDE CHAMBER PROCESS MONITOR FOR ADSORPTIVE SEPARATION PROCESS - Processes and apparatus for analyzing fluid properties of a stream are described. The processes utilize a simulated moving bed system and a rotary valve. The processes involve sending a portion of the pump-around stream to a side chamber where the moisture content of the adsorbent in the side chamber or one or more fluid properties of the stream or both are measured using an analyzer specific to each fluid property. | 2021-08-19 |
20210255153 | SYSTEMS AND METHODS OF DETERMINING ISOTOPIC COMPOSITION OF GASEOUS SAMPLES - A system for determining isotopic composition of a gaseous sample. The system includes at least one gas chromatograph for separating the gaseous sample into gaseous components. Furthermore, the system includes a combustion furnace operatively coupled with the at least one gas chromatograph for oxidizing the gaseous components. Moreover, the system includes a water separator operatively coupled with the combustion furnace. Furthermore, the system includes an isotope-ratio mass spectrometer operatively coupled with the water separator. Moreover, the isotope-ratio mass spectrometer comprises an ion source for generating ion beams associated with each of the oxidized gaseous components and a mass analyser for receiving the generated ion beams from the ion source, wherein the mass analyser is operable to determine isotopic concentrations associated with each of the ion beams. Furthermore, the isotope-ratio mass spectrometer is operable to use the determined isotopic concentrations to determine the isotopic composition of the gaseous sample. | 2021-08-19 |
20210255154 | DEVICE WITH DEUTERIUM LAMP AND LIQUID CHROMATOGRAPH - The device is provided with a lamp lighting unit configured to perform an operation for lighting a deuterium lamp by controlling a lamp drive unit and a heater drive unit, an abnormality determination unit configured to determine, in a prescribed sequence, whether or not a voltage or a current detected by a lamp voltage detection unit, a lamp current detection unit, a heater voltage detection unit, and a heater current detection unit is abnormal, and an abnormality cause identification unit configured to identify, in a case the voltage or the current is determined to be abnormal by the abnormality determination, the cause of the abnormality, based on the timing at which the abnormality determination unit determines that the voltage or the current is abnormal. | 2021-08-19 |
20210255155 | SYSTEM AND METHOD FOR CALIBRATING INSPECTION OF A FEATURE ON A PART - Methods and systems for calibrating inspection of a feature on a part are described. The method comprises acquiring, at a plurality of point cloud densities, measurement data from a reference part having a known defect associated with the feature; assessing the measurement data at the plurality of point cloud densities to detect the known defect; determining a lowest point cloud density from the plurality of point cloud densities at which the known defect is detectable; and setting an inspection point cloud density for inspection of the feature to the lowest point cloud density. | 2021-08-19 |
20210255156 | LEARNING MODEL GENERATION SUPPORT APPARATUS, LEARNING MODEL GENERATION SUPPORT METHOD, AND COMPUTER-READABLE RECORDING MEDIUM - A learning model generation support apparatus | 2021-08-19 |
20210255157 | OPTIMIZED MULTI-STAGE INTERMITTENT FUGITIVE EMISSION DETECTION - A method is provided for mitigating fugitive methane emission, which includes scanning a plurality of facilities for fugitive methane emission using an airborne sensor, and classifying the plurality of facilities based on results of the scanning. Optionally, further inspection of at least one facility of the plurality of facilities can be performed to detect and locate fugitive methane emission based on the classifying. Optionally, at least one facility can be selectively repaired based on the further inspection in order to mitigate fugitive methane emission. In another aspect, a planning workflow is provided that employs a clustering method to define cluster data representing a set of facility clusters in a geographical region that are associated with a particular base. The cluster data can be processed to determine flight path data representing flight path segments or route that form a trip, wherein the trip originates at the particular base, travels to a sequence of facility clusters and scans each facility in each facility cluster, and returns back to the particular base, wherein the sequence of facility clusters of the trip corresponds to the set of facility clusters represented by the cluster data. | 2021-08-19 |
20210255158 | EMISSIONS ESTIMATE MODEL ALGORITHMS AND METHODS - Systems, devices, and methods including a processor having addressable memory, the processor configured to: receive an unmanned aerial vehicle (UAV) data packet, where the UAV data packet comprises methane concentration data and UAV information from a UAV flight path; receive at least one Meteorological data packet, where the Meteorological data packet comprises weather data; combine the UAV data packet with a nearest Meteorological data packet; and determine a methane emission rate of a methane source based on the combined UAV data packet and the nearest Meteorological data packet. | 2021-08-19 |
20210255159 | ETHYLENE SENSOR - Wacker oxidation can be used as a signal transduction mechanism for the selective and sensitive detection of ethylene in air via chemiresistive sensing. Using this system, the senescence of lisianthus flowers and carnations can be monitored. | 2021-08-19 |
20210255160 | METHOD AND APPARATUS OF PREPARING OF A SILAGE GOOD AND ENSILING PROCESS - The invention refers to a method of preparing of a silage good having improved quality, to an ensiling process employing the method or the silage good, and an apparatus of preparing of a silage good having improved quality. | 2021-08-19 |
20210255161 | PARALLEL PLATE CAPACITOR SYSTEM FOR DETERMINING IMPEDANCE CHARACTERISTICS OF MATERIAL UNDER TEST (MUT) - Various aspects of the disclosure relate to evaluating the electromagnetic impedance characteristics of a material under test (MUT) over a range of frequencies. In particular aspects, a system includes: an electrically non-conducting container sized to hold the MUT, the electrically non-conducting container having a first opening at a first end thereof and a second opening at a second, opposite end thereof; a transmitting electrode assembly at the first end of the electrically non-conducting container, the transmitting electrode assembly having a transmitting electrode with a transmitting surface; and a receiving electrode assembly at the second end of the electrically non-conducting container, the receiving electrode assembly having a receiving electrode with a receiving surface, wherein the receiving electrode is approximately parallel with the transmitting electrode, and wherein the transmitting surface of the transmitting electrode is larger than the receiving surface of the receiving electrode. | 2021-08-19 |
20210255162 | PIPELINE INTERCHANGE/TRANSMIX - In one embodiment, a process is taught where the process begins by flowing a first product through a first pipeline and flowing a second product through a second pipeline. In this embodiment, the first product in the first pipeline is analyzed with a first product automated analyzer that is capable of physical and/or chemically analyzing the first product in the first pipeline and generating a first product data. Additionally, in this embodiment, the second product in the second pipeline is analyzed with a second product automated analyzer that is capable of physical and/or chemically analyzing the second product in the second pipeline and generating a second product data. The process then produces a blended product by mixing both the first product and the second product within a pipeline interchange which is connected downstream to both the first pipeline and the second pipeline. The blended product then flows from the pipeline interchange to a third pipeline that is connected downstream of pipeline interchange. The first product data and the second product data is then interpreted in a data analyzer by comparing the physical and/or chemical characteristics of the physical and/or chemical characteristics of the first data to an optimal first data and the physical and/or chemical characteristics of the second data to an optimal second data. The data analyzer then determines the adjustments in the flow of the first product and the flow of the second product to achieve optimal blended data from the blended product. The adjustments are then communicated to adjust the flow of the first product in the first pipeline and the flow of the second product in the second pipeline. | 2021-08-19 |
20210255163 | METHOD FOR ASSESSING THE COMPATIBILITY OF PRODUCTION FLUID ADDITIVES - A method of determining the suitably of corrosion inhibitors, or other additives in the presence of corrosion inhibitor, for a given fluid environment. The method including determining if there is a difference in the presence or level of micelles between a fluid sample to which corrosion inhibitor has been added either alone or to which corrosion inhibitor and at least one additional fluid additive or additives have been added. The method can be used to determine the compatibility of fluid additives. | 2021-08-19 |
20210255164 | ON-CHIP PLATFORM FOR SINGLE-MOLECULE ELECTRICAL CONDUCTANCE MEASUREMENTS - A micro-electromechanical platform and array system and methods for identifying microbial species with single molecule electrical conductance measurements are provided. The electromechanical platform has a two-tier actuation mechanism with a long stroke provided by a comb drive and a fine stroke provided by an in-plane flexural actuator. The platform is capable of making contact with a single-molecule, applying a bias, measuring the current, and performing a large number of measurements for statistical analysis. The system is capable of detecting any microbial species without requiring enzymatic amplification by detecting specific RNA sequences, for example. With oligonucleotide target molecules, the conductance is extremely sensitive to the sequence so even single-nucleotide polymorphisms can be identified. The system can also discern between subspecies using the same DNA probe. The system provides reliable, efficient, and inexpensive detection and species-level identification of microorganisms in complex detecting environments. | 2021-08-19 |
20210255165 | METHOD OF ASSESSING AGING OF ERYTHROCYTES - A method for assessing aging of erythrocytes that includes preparing an erythrocyte suspension from a blood sample; a allowing the erythrocyte suspension to pass through a first filter, separating aged erythrocytes that do not pass through the first filter, and non-aged erythrocytes that pass through the first filter, and to calculate a deformability of erythrocytes, allowing the separated non-aged erythrocyte suspension to pass through a second filter having micropores which diameter is smaller than the first filter, separating mild aged erythrocytes that do not pass through the second filter and juvenile erythrocytes that pass through the second filter, and to calculate a deformability of the non-aged erythrocytes; and assessing aging of erythrocytes, using the deformability of erythrocyte and the deformability of non-aged erythrocyte. | 2021-08-19 |
20210255166 | GDF-15 AS A HAEMATOLOGICAL TOXICITY BIOMARKER - The present disclosure relates to use of GDF-15 as a safety biomarker for determining a toxicological effect of a Mdm2 inhibitor; an ex vivo method for determining a toxicological effect of a Mdm2 inhibitor in a subject, in particular for determining a likelihood of developing thrombocytopenia in a subject in response to administration of a dose of a Mdm2 inhibitor; methods of using a Mdm2 inhibitor in the treatment of cancer in a subject; a kit for use in predicting the likelihood that a patient having cancer will develop thrombocytopenia in response to a treatment with a dose of a Mdm2 inhibitor; a kit for use in treating a patient having cancer and related disclosure embodiments. | 2021-08-19 |
20210255167 | COMPOSITIONS AND METHODS FOR ASSESSING TOXICITY USING DYNAMIC BH3 PROFILING - The present invention provides methods of assessing toxicity using Dynamic BH3 profiling. | 2021-08-19 |
20210255168 | A METHOD OF PRECISION CANCER THERAPY - The present invention relates to a method of treatment of cancer, said method comprising administering an effective dose of a protein kinase inhibitor to a patient in need thereof having said cancer. The present invention also relates to a method of post-transcriptional control of cancer-related genes comprising administering an effective amount of a protein kinase inhibitor to a subject in need thereof. The present invention further relates to a method of identifying a protein kinase inhibitor for normalizing post-transcriptional regulation as precision cancer therapy. | 2021-08-19 |
20210255169 | Method Of Selecting Stem Cells Having Ability To Produce Extracellular Vesicles With High Efficiency Using Activation Of Protease-Activated Receptor-Mediated Signaling Pathways - The present disclosure relates to a method of selecting stem cells having the ability to produce extracellular vesicles with high efficiency, the method including the step of measuring the activity of protease-activated receptor (PAR)-mediated signaling pathways, stem cells selected by the method, and a method of screening an inducer for the production of extracellular vesicles. According to the present disclosure, upon treatment of stem cells with thrombin, the production of extracellular vesicles in the stem cells and the levels of proteins in the extracellular vesicles are significantly increased via PAR-mediated signaling pathways, and thus stem cells having the ability to produce extracellular vesicles with high efficiency can be efficiently selected by treating stem cells with thrombin and measuring an activation level of a PAR-mediated signaling pathway, and stem cells selected by this method can be effectively used in related research and clinical fields. | 2021-08-19 |
20210255170 | INDUCTIVE REGENERATION OF THE AIRWAY BY TRANSCRIPTIONAL FACTOR MODULATION OF GLANDULAR MYOEPITHELIAL STEM CELLS - Compositions and methods to modulate Lef-1/TCF/Wnt signaling ex vivo or in vivo, and assays to detect those modulators, are described. | 2021-08-19 |
20210255171 | DEVICE AND METHOD FOR DISTINGUISHING SMOKING E-CIGARETTE FROM SMOKING CIGARETTE - The invention provides a device and method for distinguishing smoking an e-cigarette from smoking a cigarette. The device includes a test strip used to detect nicotine or its analogues in a sample; and a test strip used to detect glycerine in the sample. The device and method of the invention can be used to effectively distinguish which cigarette a user is smoking, the e-cigarette or a tobacco product. This is conductive to providing more accurate treatment and intervention for nicotine abusers. | 2021-08-19 |
20210255172 | Sensor and Method for Detecting Target Molecules - An apparatus and method for detecting one or more target molecules includes a hydrophobic substrate, and a sensor. The sensor includes two or more electrodes disposed on the hydrophobic substrate and separated from one another by a gap, a plurality of nanostructures formed on or within an upper surface of each electrode, a plurality of binding molecules attached to the plurality of nanostructures, wherein the plurality of binding molecules are configured to bind with the one or more target molecules, and wherein the upper surface of each electrode and the plurality of nanostructures are hydrophilic, and may further detect two or more analytes with two or more sensors that detect two or more different modalities, such as, electrical, optical fluorescence, optical resonance, magnetic detection, or acoustic waves. | 2021-08-19 |
20210255173 | METHODS FOR ASSESSING CELL SURFACE GLYCOSYLATION - Provided herein are methods for assessing cell surface glycans, e.g., N-glycans, by assessing a sample of released surface glycans, and determining the presence, absence, or level of glycans present in the sample. Also provided are methods of assaying and/or evaluating a cell composition by assessing the cell surface glycan profile of the cell composition and comparing the profile to a reference sample. Methods for manufacturing and/or culturing a plurality of cell compositions having consistent surface glycan expression with low variability are also provided. | 2021-08-19 |
20210255174 | METHODS FOR DETECTION OF BOTULINUM NEUROTOXIN - Provided herein is a large immuno-sorbent surface area assay (ALISSA) for the rapid and sensitive detection of botulinum neurotoxins (BoNTs) and anthrax toxin. This assay is designed to capture a low number of toxin molecules and to measure their intrinsic protease activity via conversion of a fluorogenic or luminescent substrate. Also provided herein are novel peptides that can be specifically cleaved by BoNT and novel peptides that are resistant to cleavage by BoNT. The combination of these cleavable and control peptides can be used for implementation of an exemplary ALISSA used to specifically detect BoNT enzymatic activity. Furthermore, the ALISSA as described herein may also be used in a column based format for use in a high-throughput system for testing large quantities of samples. | 2021-08-19 |
20210255175 | Spatially Encoded Biological Assays - The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature. | 2021-08-19 |
20210255176 | SYSTEMS FOR DETECTION - Cell-based sensor devices, systems, and methods for the detection and identification of volatile compounds, and for the determination of the location of the source of the volatile compounds in an enclosed space are described. | 2021-08-19 |
20210255177 | HOMOGENEOUS ASSAY WITH PARTICLE AGGREGATION OR DE-AGGREGATION - Disclosed are devices and methods for performing biological and chemical assays, such as immunoassays and nucleic acid assays, more particularly a homogeneous assay that does not use a wash step by using the aggregation and de-aggregation processes of microparticles or nanoparticles. | 2021-08-19 |
20210255178 | SUBSTRATE WITH CHANNELS FOR CONTROLLED FLUID FLOW IN BIOLOGICAL ASSAY SAMPLING - Immunoassay devices with plurality of fluid flow channels that are discrete and designed for optimal fluid control are described. Substrates configured to control the rate of fluid flow for in-situ immunoassay measurements to detect and quantify the presence of one or more analytes of interest in a sample are also described. More specifically, the present disclosure relates to consumables for lateral flow assays, which in conjunction with an instrument detect markers or causative agents of medical conditions. | 2021-08-19 |
20210255179 | METHOD FOR DETECTING A TEST SUBSTANCE - A method for detecting a test substance using a composition that contains gold nanoplates suitable for detecting the test substance. The composition includes gold nanoplates, and is characterized in that an average aspect ratio of the gold nanoplates (a value obtained by dividing a maximum length of the gold nanoplates by a thickness) is greater than 1 and 10 or less, a concentration of quaternary ammonium cations in the composition is 1 mM or less, and the quaternary ammonium cations are represented by N | 2021-08-19 |
20210255180 | Methods and Kits for Detection of 11-dehydro-thromboxane B2 - Methods, compositions and kits for quantitatively determining specified amounts of 11dhTxB2 in microliter to milliliter quantities of a given sample, wherein, the sample is a biological fluid. Specifically, the biological fluid is a quantity of 1 ml or less of urine from a human subject. The methods may be in the form of consolidated assays that can be run in a high throughput, automation format, such as an enzyme-linked immunosorbent assay (ELISA). Further, the ELISA may be modified into a chemiluminescence assay in order to increase sensitivity and linear range and to reduce the reaction time. | 2021-08-19 |
20210255181 | DIAGNOSTIC ASSAYS USING BACTERIAL QUORUM SENSING SIGNALS - Disclosed are methods, systems, devices, and kits for diagnosing and/or monitoring a bacterial infection in a subject in need thereof. The methods, systems, devices, and kits are useful for identifying causative bacteria, such as | 2021-08-19 |
20210255182 | LATERAL FLOW ASSAY DEVICE AND ANALYSER - A device comprises: a receptacle having a bottom wall portion closing a first end of the receptacle to delimit an inner space and having a receptacle opening at an opposite second end; a compartment for holding a lateral flow assay test strip, the compartment having a lower portion located closer to the first end than to the second end; a passageway in fluid communication with the lower portion of the compartment; and a lid configured to overlay the receptacle opening and comprising a body portion. A sample receiving portion is located in said body portion and is arranged in fluid communication with the inner space. The passageway is delimited by a first opening into the lower portion of the compartment and a second opening in the lid. | 2021-08-19 |
20210255183 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF BIOLOGICAL PREPARATION ON RHEUMATOID ARTHRITIS - The objective of the present invention is to provide a method for simply, inexpensively and accurately assessing, before administering a biological preparation, the therapeutic effect thereof (in particular whether there will be a complete response) or the improvement of symptoms in patients having rheumatoid arthritis. | 2021-08-19 |
20210255184 | Biosensor Device and Methods - The invention provides a sensor device comprising an insect odorant receptor complex, comprising an OrX and an Oreo, in electrical communication with a substrate, wherein the sensor device is configured to detect a change in an electrical characteristic of the substrate. The invention also provides sensor device component comprising an insect odorant receptor complex, comprising an OrX and an Oreo, in electrical communication with a substrate. The invention also provides methods for manufacture and use of the sensor device and sensor device component. The invention also provides methods of use of the sensor to detect an analyte. | 2021-08-19 |
20210255185 | CELL-BASED ASSAY FOR MEASURING DRUG PRODUCT POTENCY - The invention relates to an in vitro quantative cell-based assay that uses a primary mouse cell model system permissive to viral vector infection and a quantitative high content image-based system for determining potency of a transgene-expressing viral vector drug product for lot disposition. | 2021-08-19 |
20210255186 | Micro-Array Devices for Capturing Cells in Blood and Methods of Their Use - The present disclosure provides micro-array devices for capturing cells in blood and methods of their use. In some aspects, a method for counting cells in a blood sample is provided, the method comprising applying a blood sample onto a CNT device; allowing cells in the blood sample to differentially settle on the CNT device, and identifying and counting cells of preselected type in the blood sample. | 2021-08-19 |
20210255187 | METHOD FOR PREDICTING THE EFFECTIVENESS OF TREATMENTS FOR CANCER PATIENTS - A method for predicting whether a patient with cancer is likely to respond to a treatment is described. The method comprises measuring a value indicative of a level of certain biomarkers; calculating a total value using a weighted sum of the measured values; comparing the total value to a threshold value and when the total value is below the threshold value, determining that the patient is likely to respond to the treatment. Alternatively, the method comprises applying a model comprising coupled ordinary differential equations defining the rate of change of a plurality of biomarkers to predict a plurality of output values for the biomarkers for the treatment; selecting a biomarker; comparing the output value for the selected biomarker to an associated threshold value for the selected biomarker; and when the output value is below the associated threshold value, determining that the patient is likely to respond to the treatment. | 2021-08-19 |
20210255188 | METHOD AND COMPOSITIONS FOR DETECTING AN ADENOMA-ADENOCARCINOMA TRANSITION IN CANCER - Methods and kits for detecting alternating spatial expression of PTEN and, optionally, SMAD4, CD44, and/or TP53 in colonic tumors are described. The methods and kits are useful for identifying a cancer stem cell (CSC)-like zone within a colonic tumor, identifying an adenoma-adenocarcinoma (Ad-ACA) transition zone in a colorectal cancer (CRC) tumor, identifying a CRC tumor that contains high-grade adenoma and/or early adenocarcinoma regions, identifying CSCs in a CRC tumor, diagnosing a subject with high-grade colon adenoma and/or early adenocarcinoma, and determining the likelihood that a colonic tumor in a subject will undergo invasive transformation if left untreated. | 2021-08-19 |
20210255189 | BIOMARKER PANEL FOR OVARIAN CANCER - The present invention relates to the identification of novel panels and combinations of biomarkers for ovarian cancer. An in vitro method is provided for detecting, predicting or monitoring ovarian cancer in a subject, wherein said method comprises determining in a sample from said subject the levels of the biomarkers in a panel comprising: TACSTD2, PROK1, MSMB, MUC-16, WFDC2, FR-alpha, and KRT19. More broadly, biomarkers may be selected and used from this list in variations combinations with each other and with other biomarkers. Also provided are sets of reagents for use in such methods. | 2021-08-19 |
20210255190 | METHODS FOR DETECTING AND TREATING CANCERS HAVING ADENOSINE PATHWAY ACTIVATION - This disclosure relates to methods for detecting a level of expression of one or more genes (or proteins) in a subject having or suspected of having cancer, and optionally treating the subject with an adenosine pathway antagonist, for example an adenosine A2A receptor (ADORA2A) antagonist, to treat the cancer. The genes (or proteins) include, without limitation, CD68, CD163, LBP, CCL2, CCL3, CCL7, CCL24, CCNE1, CD 14, CD300E, CD86, CD93, CLEC5A, CSF3, CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL8, DFNA5, ECEL1, EPB41L3, EHF, FUT7, GALM, GBP6, GPR157, HAS1, IL1A, IE-1β, 1L23, 1L24, IL5, 1L6, 1L8, INHBA, LAP3, LAYN, LOC100505585, MRPL11, NID1, OST4, PADI2, PID1, PLAUR, PPBP, PTGS2, RHCG, SERPINB2, SLC11A1, SLC7A7, SPON1, ST6GALNAC2, TBX21, THBS1, C1R, C1S, C4BPA, CCL11, CCL20, CXCL16, CXCL2, HAMP, HSD11B1, IT GAM, LIF, SAA1, TFRC, TLR5, TNFSF14, TREM2, APP, ATG10, BCL2, CCL15, CD24, CD46, CD59, CREB5, CX3CL1, CXCL14, CYFIP2, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. | 2021-08-19 |
20210255191 | FLUORESCENT DYE AND USE THEREOF - Disclosed is: a fluorescent dye comprising a compound, a tautomer of the compound, or a salt of the compound or the tautomer; a labeled composite substance comprising the fluorescent dye and a composite substance which are bonded to each other; a composition containing the fluorescent dye or the labeled composite substance; and a method for acquiring information about a substance of interest by a super-resolution microscopy. | 2021-08-19 |
20210255192 | METHODS AND KITS FOR DETECTING MISFOLDED PROTEINS - Methods, kits and compounds are provided that relate to the diagnosis, treatment, and/or prevention of preeclampsia. | 2021-08-19 |
20210255193 | LYSINE REACTIVE PROBES AND USES THEREOF - Disclosed herein are methods and compounds for profiling a lysine reactive protein. Also described herein are methods, compounds, and compositions for identifying a small molecule fragment ligand that interacts with a reactive lysine residue. | 2021-08-19 |
20210255194 | METHODS FOR IDENTIFYING AND ANALYZING AMINO ACID SEQUENCES OF PROTEINS - The disclosure provides methods for determining the biosimilarity of a test protein in relation to a target biologic in which the test protein is digested by two distinct proteases, the resultant digested peptide fragments are analyzed by column chromatography-tandem mass spectrometry to achieve 100% of the amino acid sequence coverage and 100% amino acid sequence accuracy of the test protein. | 2021-08-19 |
20210255195 | HIGH PRECISION SPECTRAL FRET ASSAYS - Provided herein are methods for identifying a compound that alters fluorescence resonance energy transfer (FRET) of a protein. In one embodiment, the method includes providing a target protein, where the target protein includes two heterologous domains, each domain having chromophores that together act as a FRET pair. In another embodiment, the method includes providing a target protein and a second protein, wherein the target protein includes a first heterologous domain including a chromophore, and the second protein includes a second heterologous domain including a chromophore, where the chromophores together act as a FRET pair. The method further includes contacting a sample including the target protein and optional second protein with a test compound to form a mixture, and measuring a fluorescence emission spectrum of the mixture during exposure to a light source. The fluorescence emission spectrum is decomposed into at least two component spectra, where in one embodiment the component spectra include a donor chromophore emission and an acceptor chromophore emission. A ratio (R) is then calculated, and in one embodiment, R is determined according to | 2021-08-19 |
20210255196 | LOW BINDING SURFACES FOR PEPTIDE MAPPING - The present disclosure discusses a method of separating a sample (e.g., peptide compound) including coating a flow path of a chromatographic system; injecting the sample into the chromatographic system; flowing the sample through the chromatographic system; separating the sample; and analyzing the separated sample. In some examples, the coating applied to the surfaces defining the flow path is non-binding with respect to the sample—and the separated sample. Consequently, the sample does not bind to the low-binding surface of the coating (e.g., organosilica coating) of the flow path. The applied coating can reduce peak tailing and increase analyte recovery for the sample of the chromatographic system. | 2021-08-19 |
20210255197 | PROTEIN COMPOSITION AND METHODS FOR ANALYSING MICROBIOTA - A method of isotope-labelling a microbiota sample. It involves providing a first microbiota sample that was obtained from a given source; exposing the first microbiota sample to an isotope enriched medium; and culturing the exposed first microbiota sample in the isotope enriched medium to obtain an isotope-labelled microbiota sample, wherein the isotope labelled metaproteome of the isotope-labelled microbiota sample is taxon specific for taxa present in the first microbiota sample when initially obtained from the given source. | 2021-08-19 |
20210255198 | METHODS FOR OBJECTIVE ASSESSMENT OF STRESS, EARLY DETECTION OF RISK FOR STRESS DISORDERS, MATCHING INDIVIDUALS WITH TREATMENTS, MONITORING RESPONSE TO TREATMENT, AND NEW METHODS OF USE FOR DRUGS - Disclosed are methods for assessing severity, determining future risk, matching with a drug treatment, and measuring response to treatment, for stress disorders. Also disclosed are new methods of use for drugs and natural compounds repurposed for use in reducing stress severity, as well as for preventing and treating stress disorders. All the above mentioned methods are computer assisted methods analyzing the expression of panels of genes, clinical measures, and drug databases. A universal approach in everybody, as well as a personalized approaches by gender, and by diagnosis, are disclosed. | 2021-08-19 |
20210255199 | PREDICTION OF DRUG-FREE REMISSION IN RHEUMATOID ARTHRITIS - Certain embodiments of the present invention relate to methods and products for use in the determination of treatment of rheumatoid arthritis (RA). Particularly, although not exclusively, embodiments of the present invention relate to predicting the likelihood of a patient suffering from rheumatoid arthritis maintaining remission following cessation of disease-modifying anti-rheumatic drugs (DMARDs). Certain embodiments of the present invention are based on the determination of certain biomarkers of drug-free remission in RA following cessation of DMARD therapy. | 2021-08-19 |
20210255200 | PREDICTING MORTALITY AND DETECTING SEVERE DISEASE - Measurement of circulating ST2 and/or IL-33 concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, and the detection of severe disease. | 2021-08-19 |
20210255201 | BLOOD-BASED METHODS FOR DETERMING A-BETA AMYLOIDOSIS - The present disclosure provides methods for blood-based examination useful to identify subjects with Aβ amyloidosis and/or to identify subjects who should or should not undergo further testing or treatment for Aβ amyloidosis, as well as methods for treating subjects diagnosed with Aβ amyloidosis by the methods disclosed herein. | 2021-08-19 |
20210255202 | METHODS AND DOSING REGIMENS FOR PREVENTING OR DELAYING ONSET OF ALZHEIMER'S DISEASE AND OTHER FORMS OF DEMENTIA AND MILD CONGNITIVE IMPAIRMENT - Methods and dosing regimens using alpha 7 acetylcholine nicotine receptor binding agents are provided to prevent or inhibit intracellular accumulation of amyloid in cells leading to inhibition or prevention of neuronal cell death. In addition, these methods and dosing regimens are coupled with methods and dosing regimens to reduce and/or prevent blood-brain barrier leakage of vascular-derived amyloid into the brain and/or methods and dosing regimens to reduce and/or prevent neuroinflammation to prevent and/or inhibit the progression of Alzheimer's disease and other forms of dementia and mild cognitive impairment. Also provided are methods for identifying individuals for this treatment. | 2021-08-19 |
20210255203 | NOVEL COMPOUNDS USEFUL AS NEAR-INFRARED FLUORESCENT PROBES SELECTIVELY BINDING TO TAU AGGREGATES AND METHOD OF PREPARING THE SAME - Disclosed are a compound with near-infrared fluorescence that selectively binds to tau aggregates, a method for preparing the same, a tau-targeting near-infrared fluorescent probe including the compound, a composition for detecting a tau fiber protein containing the near-infrared fluorescent probe as an active ingredient, and the use of the composition for the diagnosis of tauopathy. In particular, the compound does not bind to an amyloid beta protein and has high selectivity to a tau aggregate, specifically reported as an etiology of the initial state of tauopathy, thus being useful as a near-infrared fluorescent detector for detecting a tau fiber protein for early diagnosis of a tauopathy including Alzheimer's disease. | 2021-08-19 |
20210255204 | BLOOD-BASED SCREEN FOR DETECTING NEUROLOGICAL DISEASES IN PRIMARY CARE SETTINGS - The present invention includes methods and kits for measuring a level of four or more biomarkers selected measuring a level of four or more biomarkers selected from ILL IL7, TNFα, IL5, IL6, CRP, IL10, TNC, ICAM1, FVII, I309, TNFR1, A2M, TARC, adiponectin, MIP1, eotaxin3, sVCAM1, TPO, FABP, IL18, B2M, SAA, PPY, DJ1, and α-synuclein, Aβ40, Aβ42, tau, α-synuclein, and NfL in a sample separated from a human subject in the primary care setting with neurological disease with a nucleic acid, an immunoassay or an enzymatic activity assay. | 2021-08-19 |
20210255205 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISEASE - The present disclosure relates to compositions and methods for modulating a subject's cholesterol levels and/or treating disorders related to high cholesterol. | 2021-08-19 |
20210255206 | Water Soluble Polymer Surfactant for Synthesis of Functionalized Polystyrene Nanobeads Towards Detection of Bilirubin in Human Serum - The present invention provides a water soluble polymer surfactant (PS-DGlu) of formula I which is utilized for synthesis of functionalized polystyrene nanobead covalently incorporating (oligo) p-phenylenevinylene (OPV) nanosensor (PSG-OPV-n) which in turn is useful for the detection of bilirubin in human serum. The present invention further provides a process for the preparation of the water soluble polymer surfactant (PS-DGlu) of formula (I) and a mini emulsion polymerization process for the synthesis of PSG-OPV-n. | 2021-08-19 |
20210255207 | BIOMARKERS FOR COLORECTAL CANCER - The present invention relates to certain volatile organic compounds which can be detected in stool samples of individuals and be used as biomarkers in determining the probability that an individual has colorectal cancer. | 2021-08-19 |
20210255208 | METHOD FOR EXTRACTION AND DETERMINATION OF FATTY ACID IN BIOLOGICAL FLUID - A method for determining fatty acid level in case of acute or chronic medical conditions, and diagnosing medical conditions associated with increased fatty acid level in a biological sample containing albumin is provided. The method includes incubation of patient's sample and high surface area carbon-based electrode together in a holder. Due to attractive hydrophobic interaction between the albumin's surface fatty acids and the carbon-based material, the electrode self-extracts fatty acids from the albumin. The method eventually includes adsorption/accumulation with subsequent monolayer formation of extracted fatty acids over the carbon-based electrode. Accumulation of the fatty acid monolayer changes already existing electrode-electrolyte (sample) interfacial construct, which in turn changes also the interfacial states, such as electrical double layer capacitance. The appropriate electrical/electrochemical measurement reflects the magnitude of extracted fatty acids from the albumin that is indicative of acute or chronic medical conditions. | 2021-08-19 |
20210255209 | METHOD FOR DIAGNOSIS OF LYME ARTHRITIS, METHOD FOR DIFFERENTIAL DIAGNOSIS OF LYME ARTHRITIS, LYSOPHOSPHATIDYLETHANOLAMINE FOR USE AS BIOMARKER, KIT FOR DIAGNOSIS OF LYME ARTHRITIS AND KIT FOR DIFFERENTIAL DIAGNOSIS OF LYME ARTHRITIS - The subject matter of the invention relates to a method for in vitro diagnosis of Lyme disease and a method for in vitro differential diagnosis of Lyme arthritis versus rheumatoid arthritis, in which methods, in a sample from a subject, the level of lysophosphatidylethanolamine comprising myristic acid (LysoPE(14:0)) is determined and such determined level of lysophosphatidylethanolamine is compared with the level of lysophosphatidylethanolamine comprising myristic acid in a reference sample; in wherein the level of lysophosphatidylethanolamine comprising myristic acid which is higher than the level in the said reference sample indicates that the subject suffers from Lyme disease. The subject matter of the invention further relates to lysophosphatidylethanolamine comprising myristic for use as a biomarker of Lyme disease, as a biomarker of Lyme arthritis, as a biomarker for differential diagnosis of Lyme arthritis versus rheumatoid arthritis, as a biomarker of neuroborreliosis. The subject matter of the invention also relates to a kit for in vitro diagnosis of Lyme disease and a kit for in vitro differential diagnosis of Lyme arthritis, which kits comprise a means for determining the level of lysophosphatidylethanolamine comprising myristic acid and instructions for carrying out the methods for diagnosis according to the invention. | 2021-08-19 |
20210255210 | AUTOSAMPLER, AUTOMATIC ANALYSIS DEVICE, SAMPLING METHOD, AND AUTOMATIC INSPECTION METHOD - An autosampler includes an installation part allowing a plurality of racks to be installed therein, a transfer part capable of holding one rack installed in the installation part and moving back and forth in a first movement direction along an installation direction, and a rack transport path used to move the rack held by the transfer part back and forth in a second movement direction intersecting the first movement direction are included. The transfer part is moved forward in the first movement direction to transfer the rack present in the installation part to a side of the rack transport path, and the transfer part is moved backward in the first movement direction to send the rack present in the rack transport path back to a side of the installation part. | 2021-08-19 |
20210255211 | METHOD AND APPARATUS FOR SENSOR ORIENTATION DETERMINATION - Some embodiments include a method and apparatus which obtains sensor data associated with a vehicle. The sensor data includes three-dimensional acceleration data and three-dimensional rotation data, with respect to a sensor coordinate system. A gravity vector is obtained, and it is determined when the vehicle starts moving. Acceleration direction is used as a forward direction of the vehicle. It is determined from the rotation data when the vehicle changes direction, the rotation data indicating two different directions. The gravity vector is used to distinguish which is an upward direction by selecting directions the direction which has larger angle with respect to the gravity vector as the upward direction. The forward direction and upward direction are used to determine a rightward direction. The forward direction, upward direction and rightward direction represent the vehicle coordinate system. The orientation of the apparatus with respect to the orientation of the vehicle is determined. | 2021-08-19 |
20210255212 | Inertial Sensor, Electronic Device, And Movable Body - An inertial sensor, includes: a substrate; a fixing portion that is provided on the substrate; a first movable body that faces the substrate and that is displaceable with a first support beam as a first rotation axis; the first support beam that is arranged in a first direction and that couples the first movable body and the fixing portion; a second movable body that is displaceable due to deformation of a second support beam; the second support beam that is arranged in a second direction intersecting the first direction and that couples the first movable body and the second movable body; and a protrusion that is provided on the substrate or the second movable body, overlaps the second movable body in plan view from a third direction and that protrudes toward the second movable body or the substrate. | 2021-08-19 |
20210255213 | MICRO-FABRICATED OPTICAL MOTION SENSOR - An optical motion sensor includes a substrate, a whispering-gallery-mode-based optical resonator disposed on the substrate, a mass-spring-damper system disposed on the substrate proximate to a first side of the whispering-gallery-mode-based optical resonator, and a waveguide or optical fiber. The whispering-gallery-mode-based optical resonator has a substantially circular cross-section. A gap separates an end of the mass-spring-damper system from the whispering-gallery-mode-based optical resonator. The waveguide or optical fiber abuts a second side of the whispering-gallery-mode-based optical resonator that is substantially opposite to the first side. | 2021-08-19 |
20210255214 | MEMS DEVICE, ELECTRONIC APPARATUS, AND VEHICLE - A MEMS device includes: a substrate as a base including a support portion and a detection electrode as a fixed electrode; a movable body supported to the support portion with a major surface of the movable body facing the fixed electrode; and an abutment portion facing at least a portion of an outer edge of the movable body and restricting rotational displacement in an in-plane direction of the major surface. The abutment portion includes an abutment surface including an abutment position at which the movable body abuts against the abutment portion due to the rotational displacement of the movable body, and a hollow portion provided opposing the abutment surface. | 2021-08-19 |
20210255215 | SYSTEM AND METHOD FOR DETERMINING DISTANCE OF FREE FALL - A sensor includes a MEMS element responsive to acceleration, an analog-to-digital converter coupled to an output of the MEMS element, and a free fall detector coupled to an output of the analog-to-digital converter. The free fall detector is configured to determine whether the sensor is in free fall based on acceleration information received from the analog-to-digital converter. A digital interface is coupled to the analog-to-digital converter and to an output of the free fall detector and is configured to issue an output related to free fall information determined by the free fall detector. | 2021-08-19 |
20210255216 | PROBE SHEET FOR NON-INVASIVE NANOSCALE ELECTRICAL CHARACTERIZATION - An apparatus is provided that includes a flexible substrate able to fold upon itself and comprising patterned probe sheet thereon or therein, which is able to conform about microscale topological features of a testing surface. The apparatus provides for the use of patterned conductive probes for surface and sub-surface electrical characterization and the use of a controllable and non-invasive adhesion mechanism for consistent and flush probe contact, such as the use of electroadhesion traces patterned about the testing perimeter or probe vias through the flexible substrate. | 2021-08-19 |
20210255217 | PROBE CARD HOLDING DEVICE AND INSPECTION DEVICE - A probe card holding device includes: a frame that holds a probe card by vacuum suction; a sealing member provided on the frame and configured to form an enclosed space by contacting the probe card; a placement section in which a first engaging portion provided at an outer circumference of the probe card is placed when the probe card is attached to the frame; a second engaging portion configured to be engaged with the first engaging portion; and an actuator configured to drive the second engaging portion between a first position and a second position. When the second engaging portion is engaged with the first engaging portion in response to dissipation of the vacuum suction, the probe card is held by the probe card holding device while the sealing member maintains a seal with the probe card. | 2021-08-19 |
20210255218 | VERTICAL PROBE HEAD WITH IMPROVED CONTACT PROPERTIES TOWARDS A DEVICE UNDER TEST - A probe head for testing a device under test includes an upper guide and a lower guide parallel to each other and spaced apart. Each of the guides is provided with a respective plurality of guide holes, a plurality of contact probes housed in the guide holes and provided each with a first end and with a second end, the first end being adapted to contact pads of a device under test. At least one additional guide is associated with one of the guides. The additional guide includes first guide holes, housing a first group of the contact probes, and second guide holes, housing a second group of the contact probes. The first and second guide holes are shifted with respect to the guide holes of the guide which said additional guide is associated with, and the shift of the first guide holes is in a direction opposite the shift of the second guide holes. | 2021-08-19 |
20210255219 | SEMICONDUCTOR FABRICATING APPARATUS INCLUDING A PROBE STATION - A semiconductor fabricating apparatus may include a probe card, a test head, a support and a chamber wall. The probe card may include a plurality of probing needles. The probe card may be installed at the test head. The support may be configured to receive a wafer including a plurality of test pads making contact with the probing needles. The chamber wall may be configured to receive the support. The chamber wall may define a chamber in which a probe test may be performed. At least one of the probe card and the support, the probe card and the test head, and the test head and the chamber wall may be combined with each other by a magnetic module. | 2021-08-19 |
20210255220 | Apparatus and Method for Securing a Watthour Electrical Meter to a Socket Box - The instant disclosure relates to an apparatus and method for securing a watthour electrical meter to a socket meter box. A locking ring comprises a divided annular band fitted with tab members configured to accept a variety of ring fasteners. The tab members support a variety of ring fastener and fastener receiver assemblies, and have complementary mating surfaces that substantially mate around the head of an installed meter so that the locking ring is tamper-resistant. The ring fastener and fastener receiver have a number of complementary apertures disposed to receive either wire seals or other locking mechanisms. | 2021-08-19 |
20210255221 | METHOD FOR MEASURING A CURRENT, AND CURRENT-MEASURING DEVICE - In a method for measuring a current, a plurality of flux-gate field sensors is arranged with radial symmetry on a first circumferential path, and a plurality of Hall sensors is arranged with radial symmetry on a second circumferential path such that a one of the flux-gate field sensors is placed adjacent a one of the Hall sensors, with the flux-gate field sensors having a sensitivity which is higher by a factor 5 to 20 than a sensitivity of the Hall sensors. At least one of the plurality of flux-gate field sensors is evaluated so as to determine a current intensity, when two of the flux-gate field sensors generate measurement values within a measurement range, or at least one of the plurality of Hall sensors is evaluated so as to determine a current intensity, when the measurement values of the two flux-gate field sensors are outside of the measurement range. | 2021-08-19 |
20210255222 | CURRENT SENSOR WITH FLUX GATE - A flux gate current sensor includes a magnetic core, a measurement winding, an excitation circuit arranged to generate a digital excitation signal, an acquisition circuit arranged to acquire an analog measurement voltage from the terminals of the measurement winding and to produce a digital measurement signal, a demagnetization servocontrol circuit arranged to use the digital measurement signal to produce a digital demagnetization signal for compensating magnetic flux produced by the current that is to be measured, a summing circuit arranged to sum the digital excitation signal and the digital demagnetization signal so as to obtain a digital injection signal, and an injection circuit arranged to produce an analog excitation current from the digital injection signal and to inject the analog excitation current into the measurement winding. | 2021-08-19 |
20210255223 | SYSTEM FOR SPIKING, I.E. EXPLORING VOLTAGE, IN ELECTRIC CABLES | 2021-08-19 |
20210255224 | VOLTAGE BOOSTER ISOLATION TRANSFORMER SYSTEM AND METHOD OF OPERATING THE SAME - A system and method for an isolation transformer boost system. The system includes an isolation transformer, a sensor, and an electronic processor coupled to the sensor. The electronic processor configured to receive an electrical characteristic measurement from the sensor, compare the electrical characteristic measurement to a predetermined threshold, and activate an electrical characteristic boost when the electrical characteristic measurement is below the predetermined threshold. | 2021-08-19 |
20210255225 | METHOD FOR MONITORING A GROUND RESISTANCE OF AN ELECTRIC INSTALLATION - A method is for monitoring a ground resistance of an electric installation which consists of an ungrounded stationary alternating-voltage power supply system having at least one active conductor and of a consumer connected to the stationary alternating-voltage power supply system via a supply line. For this method, the already available active conductors of the stationary alternating-voltage power supply system and the leakage capacity of the leakage capacitor installed in the consumer are used to complete a measuring-current circuit for monitoring the ground resistance, a measuring signal being capacitively coupled between the active conductor and ground via a coupling circuit. Measuring currents and measuring voltages are measured when the consumer is switched on and off, a complex-valued load-side impedance, which has the ground resistance to be monitored in its real part, being detected from these measurements. | 2021-08-19 |
20210255226 | Photonic-Crystal Vapor Cells for Imaging of Electromagnetic Fields - In a general aspect, vapor cells are disclosed that include a dielectric body having a first surface and a second surface. The dielectric body includes a plurality of cavities extending from the first surface to the second surface and ordered periodically to define a photonic crystal structure in the dielectric body. Each cavity has a first opening defined by the first surface and a second opening defined by the second surface. The photonic crystal structure has a photonic band gap. The vapor cells additionally include a first optical window covering the first openings and having a surface bonded to the first surface of the dielectric body to form a seal around each of the first openings. A second optical window covers the second openings and has a surface bonded to the second surface of the dielectric body to form a seal around each of the second openings. | 2021-08-19 |
20210255227 | Miniaturized Horn Antenna Suitable for Ultra-Wideband Measurement - Some embodiments of the present disclosure provide a miniaturized horn antenna suitable for ultra-wideband measurement, and relates to the technical field of horn antennas. The antenna includes a horn antenna body, a coaxial connector and a mounting base, wherein the horn antenna body includes an upper plate, a lower plate, a side plate and a cover plate which are provided with ridges, mounting seats being formed on front and rear sides of an upper half cavity and a lower half cavity, several threaded holes being provided in the mounting seats separately, an upper mounting groove and a lower mounting groove being formed between the mounting seats of the upper plate and between the mounting seats of the lower plate respectively, the upper mounting groove and the lower mounting groove jointly forming a mounting space of a protrusion part at a left end of the cover plate. | 2021-08-19 |
20210255228 | RYDBERG-PARTICLE-BASED 3D MICROWAVE SENSOR - A 3D microwave sensor includes a cloud of particles, e.g., rubidium 87 atoms. A laser system produces: a first probe beam directed through the particle cloud along a first path; a second probe beam directed through the particle cloud along a second path that intersects the first path to define a Rydberg intersection; a first coupling beam that counterpropagates with respect to the first probe beam along the first path; and a second coupling beam that counterpropagates with respect to the second probe beam along the second path. A spectrum analyzer characterizes the microwave field strength at the Rydberg intersection. The laser beams can be steered to move the Rydberg intersection within the particle cloud to compile a microwave field strength distribution in the particle cloud. | 2021-08-19 |
20210255229 | CONDUCTOR TEST EQUIPMENT - The invention provides a system for locating a fault in a conductor such, as a break in a buried wire. The system includes a first conductor portion and a second conductor portion separated from each other by the fault, the system including a field generator, having: a first connection connectable to the first conductor portion, a first signal generator configured to apply a first oscillating signal between the first connection and an earth, the first oscillating signal having a frequency of between 1 and 20 kHz, and a mobile detector for detecting an electric field produced by the application of the first oscillating signal to the first conductor portion, the detector including a capacitive sensor element, a signal processor to which the sensor element is connected and having an output, and a monitor receiving the output from the signal processor and providing a signal to an operator to indicate the position of the fault. | 2021-08-19 |
20210255230 | BINARY REFLECTOMETRY SYSTEM FOR ANALYSING FAULTS IN A TRANSMISSION LINE - A reflectometry system for analyzing faults in a transmission line, a reference signal being generated, in an initial step, and injected in the transmission line, the system includes a device (CPL) for acquiring the analog signal back-propagated in the transmission line, an equalization circuit (EGA) configured for equalizing the amplitudes obtained on the reflectogram for the peaks of the injected signal after its point of injection into the transmission line and of the signal reflected on the end of the transmission line, a binarization device (B) for converting the back-propagated analog signal into a signal digitized over two quantization levels, a correlator (COR) configured for correlating the digitized signal with the reference signal in order to produce a time-domain reflectogram, a module for analyzing the time-domain reflectogram in order to identify the presence of faults in the transmission line. | 2021-08-19 |
20210255231 | BREAKDOWN VOLTAGE DETECTION - A semiconductor structure for measuring a breakdown voltage of a pn-junction, said semiconductor structure comprises:
| 2021-08-19 |
20210255232 | ARC DETECTION METHOD AND APPARATUS USING STATISTICAL VALUE OF ELECTRIC CURRENT - An embodiment of the present disclosure provides an arc detection method, in which an apparatus detects arcs, comprising the steps of: obtaining time series data for measured values of an electric current flowing in a wire; calculating first statistical values indicating dispersion degrees with time of the measured values or dispersion degrees with time of variances of the measured values from the time series data; and determining that an arc occurs in the wire or that the possibility of arc occurrence in the wire is high in a case when at least one of the first statistical values is out of a predefined range. | 2021-08-19 |
20210255233 | TESTING APPARATUS - A testing apparatus includes multiple testing units arrayed in a first axial direction in plan view, the multiple testing units being configured to respectively press probes against electronic devices on chucks to test the electronic devices, multiple gas circulating units respectively disposed in areas each corresponding to one or more testing units among the multiple testing units, the multiple gas circulating units respectively including first fans configured to circulate a gas in the areas along a second axial direction in plan view, multiple temperature detecting units configured to respectively detect temperatures of the chucks, and a controller configured to control drive of the first fans of the multiple gas circulating units based on the detected temperatures of the chucks. | 2021-08-19 |
20210255234 | TEST SYSTEM AND THE METHOD FOR TESTING A SEMICONDUCTOR DEVICE - A test system includes: an input signal generation unit that generates an input signal that drives a semiconductor device as a test target; a reference signal generation unit that supplies a reference signal, which is for use in generating the input signal, to the input signal generation unit; and a detection unit that, while implementing a test of the semiconductor device, generates a standard signal in which the same signal output as an output of the reference signal output from the reference signal generation unit is expected, and outputs a detection unit output signal based on the reference signal and the standard signal. | 2021-08-19 |
20210255235 | Method and Circuit for Testing the Functionality of a Transistor Component - In an embodiment, a method for testing a functional integrity of a transistor component, the method includes causing a first change of a charge state of an internal capacitance between control terminals of the transistor component; determining a capacitance value of the internal capacitance based on the first change of the charge state; causing a second change of the charge state of the internal capacitance; and evaluating a resistance value of an internal resistance between the control terminals based on the determined capacitance value and the second change of the charge state. | 2021-08-19 |