34th week of 2009 patent applcation highlights part 44 |
Patent application number | Title | Published |
20090209401 | Flapper roll - A flapper roll including a resilient substantially cylindrical core and extending radially outwardly therefrom a spaced array of resilient rearwardly cantilevered curved flapper flanges lying in a plane substantially containing a direction of flow of workpieces passing under the roll. The flanges are rearwardly curved relative to a direction of rotation of the roll about a corresponding axis of rotation. The axis is orthogonal to the plane. Each flange may be substantially flat across its width in a direction parallel to said axis so as to substantially evenly distribute across the width a resiliently biased downward force applied to the workpieces passing under the roll. Each flange is compressed as it engages the top surface of its corresponding workpiece to thereby substantially evenly hold down the workpiece and stabilize the workpiece directionally along its intended flow path. | 2009-08-20 |
20090209402 | CENTRIFUGAL SEPARATION SYSTEM - The invention relates to a system, and a set ( | 2009-08-20 |
20090209403 | CONFIGURATION OF A CYCLONE ASSEMBLY AND SURFACE CLEANING APPARATUS HAVING SAME - A cyclone separator useable in a surface cleaning apparatus comprises a cyclone casing defining a cyclone chamber and a dirt collection chamber exterior to the cyclone chamber. The cyclone chamber and the dirt collection chamber are openable such that the entire cross sectional area of the cyclone chamber and the dirt collection chamber may be exposed. | 2009-08-20 |
20090209404 | Mechanism for generating directional thrust from a centrifuge - A mechanism for generating directional thrust from a centrifuge, related to an engine that includes; a framework ( | 2009-08-20 |
20090209405 | Method for Synthesizing Bulk Ceramics and Structures from Polymeric Ceramic Precursors - A method and product made by using a polymeric ceramic precursor to synthesize dense, crack-free bulk ceramics in a technique using a sacrificial mold provides a ceramic structure for many technical, medical and industrial applications. The novel process uses an open cell material as a sacrificial mold to shape a ceramic precursor during curing. The cured ceramic green body can be machined and shaped to form the desired ceramic structure prior to final pyrolysis. The open cell material forms gas release paths to release large amount of gases generated during the pyrolysis of the cured ceramic precursor. After pyrolysis, an intact, dense, crack-free ceramic structure with high purity, strength and durability is obtained. Uses of the present invention include, but are not limited to, bulk ceramic parts, ceramic crucibles, a replacement material in some applications involving glass, silicon carbides, silicon nitrides, hafnium carbide and the like. | 2009-08-20 |
20090209406 | Enhancement of Molecular Sieve Performance - A catalyst for converting methanol to light olefins and the process for making and using the catalyst are disclosed and claimed. SAPO-34 is a specific catalyst that benefits from its preparation in accordance with this invention. A seed material is used in making the catalyst that has a higher content of the EL metal than is found in the principal part of the catalyst. The molecular sieve has predominantly a roughly rectangular parallelepiped morphology crystal structure with a lower fault density and a better selectivity for light olefins. | 2009-08-20 |
20090209407 | Selective Hydrogenation Process Using Layered Catalyst Composition and Preparation of Said Catalyst - A selective hydrogenation process and a layered catalyst composition for use in the selective hydrogenation process are disclosed. The process is useful for the selective hydrogenation of diolefins having from about 8 to about 19 carbon atoms per molecule to monoolefins. | 2009-08-20 |
20090209408 | Exhaust Gas-Purifying Catalyst - A high exhaust gas-purifying efficiency is achieved. An exhaust gas-purifying catalyst includes a substrate, an oxygen storage layer covering the substrate and including an oxygen storage material, and a catalytic layer covering the oxygen storage layer and including palladium, rhodium and a carrier supporting them, the catalytic layer having a precious metal concentration higher than that of the oxygen storage layer. | 2009-08-20 |
20090209409 | HYDROGEN STORAGE MATERIAL AND RELATED PROCESSES - Disclosed herein is a composition comprising a complex hydride and a borohydride catalyst wherein the borohydride catalyst comprises a BH | 2009-08-20 |
20090209410 | Photocatalytic hydrophilifiable material - A composite material includes a substrate and a self-cleanable hydrophilic surface layer. The surface layer includes a plurality of components: a first component having a photocatalyst which functions as a catalyst upon exposure to light; a second component having one or more of aluminum oxide, zinc oxide, strontium oxide, barium oxide, magnesium oxide, calcium oxide, rubidium oxide, sodium oxide, potassium oxide and phosphorus pentoxide; and a third component having one or more of silicon dioxide, zirconium dioxide, germanium dioxide and thorium dioxide. The first through third components are all situated within the surface layer, which is provided as a single surface layer, such that all of the components are in close proximity to one another within the single surface layer. | 2009-08-20 |
20090209411 | Enhancement of Molecular Sieve Performance - A catalyst for converting methanol to light olefins and the process for making and using the catalyst are disclosed and claimed. SAPO-34 is a specific catalyst that benefits from its preparation in accordance with this invention. A seed material is used in making the catalyst that has a higher content of the EL metal than is found in the principal part of the catalyst. The molecular sieve has predominantly a roughly rectangular parallelepiped morphology crystal structure with a lower fault density and a better selectivity for light olefins. | 2009-08-20 |
20090209412 | Attrition Resistant Fluidizable Reforming Catalyst - A method of preparing a steam reforming catalyst characterized by improved resistance to attrition loss when used for cracking, reforming, water gas shift and gasification reactions on feedstock in a fluidized bed reactor, comprising: fabricating the ceramic support particle, coating a ceramic support by adding an aqueous solution of a precursor salt of a metal selected from the group consisting of Ni, Pt, Pd, Ru, Rh, Cr, Co, Mn, Mg, K, La and Fe and mixtures thereof to the ceramic support and calcining the coated ceramic in air to convert the metal salts to metal oxides. | 2009-08-20 |
20090209413 | MODIFIED CATALYST SUPPORTS - A modified catalyst support exhibiting attrition resistance and/or deaggregation resistance is provided. A catalyst composition including the modified catalyst support is also provided. A process to produce a modified catalyst support including treatment of a support slurry with a solution of monosilicic acid is provided. A process to use a catalyst including the modified catalyst support in a Fischer-Tropsch synthesis is provided. | 2009-08-20 |
20090209414 | CATALYST COMPOSITION PREPARATION AND USE - A bulk metal oxide catalyst composition of the general formula | 2009-08-20 |
20090209415 | Composite material, composite material substrate, composite material dispersed fluid, and manufacturing methods thereof - A composite material includes an aggregate which contains a first metal particle constituting a core and second metal oxide particulates surrounding the first metal particle and having an average primary particle diameter ranging from 1 to 100 nm. | 2009-08-20 |
20090209416 | EXHAUST GAS-PURIFYING CATALYST | 2009-08-20 |
20090209417 | Method for treating flue gas catalysts - A method for treating a catalyst base that comprises a contact area of porous material. A fluid, such as a flue gas stream, can be conducted along the contact area. A catalytically relevant substance is introduced into pores of the catalyst base using a transport fluid and remains on pore wall areas after removal of the transport fluid. The introduction is carried out such that an amount of the catalytically relevant substance relative to the surface remains on the pore wall areas as a function of location within the pore and decreases within the pore after exceeding a specific pore depth. A blocking fluid can first be introduced into pore regions beyond the specific pore depth, thus blocking these regions when transport fluid containing the catalytically relevant substance is introduced. | 2009-08-20 |
20090209418 | ADSORBENT AND METHOD FOR MANUFACTURING THE SAME - Silica gel is impregnated as an impregnating substance into pores of an activated carbon having mesopores and macropores. Since the mesopores and the macropores are impregnated with the silica gel, they are made narrow and small whereby a pore size ratio within a range of 1 to 10 nm is increased. | 2009-08-20 |
20090209419 | THERMAL RECORDING ADHESIVE LABEL - A thermal recording adhesive label, including a substrate; a thermal recording layer located overlying one side of the substrate, including a leuco dye and a color developer; a back coat layer located overlying the other side of the substrate; an adhesive layer located overlying the back coat layer; and a release paper located overlying the adhesive layer, wherein the thermal recording adhesive label further includes an adhesive undercoat layer comprising a thermoplastic resin and a filler between the back coat layer and the adhesive layer. | 2009-08-20 |
20090209420 | HYPERABSORPTIVE NANOPARTICLE COMPOSITIONS - A multilayer article is provided comprising a metallic nanoparticle layer and a reflective film layer. The article may be marked on exposure to incident light. | 2009-08-20 |
20090209421 | THERMAL PRINTING LAYER AND OPTICAL RECORDING MEDIUM - There are provided a thermal printing layer suitable for thermal printing with a thermal head, and further provided a thermal printing layer which exhibits no limitations on selection of materials for the thermal printing layer. It relates to a thermal printing layer capable of thermal printing with a thermal head, which comprises a color former layer comprising a heat-sensitive color development material and a curable resin and a developer layer comprising a developer and a curable resin. Also, it relates to an optical recording medium comprising the thermal printing layer and a recording/reading functional layer. | 2009-08-20 |
20090209422 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives - Certain substituted aminoalkyl heteroaryl and heterocyclyl derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula I: wherein R, R | 2009-08-20 |
20090209423 | CORN PROTEIN CONCENTRATES - The invention provides for corn protein concentrates (CPC). The CPC described here can be used for herbicidal, fertilizer, and nutrient media benefits. | 2009-08-20 |
20090209424 | Stable Dispersions of Sulfentrazone in a Continuous Phase of Aqueous Glyphosate Salt - The present invention is directed to novel suspension concentrate compositions comprising finely milled crystalline sulfentrazone suspended in an aqueous glyphosate salt phase containing a surfactant component that chemically and physically stabilizes the composition. | 2009-08-20 |
20090209425 | ALKOXYLATED ALKYLAMINE QUATERNARY SURFACTANTS FOR GLYPHOSATE - The present invention relates to stable glyphosate formulations with improved efficacy by a highly effective alkoxylated alkylamine quaternary surfactant at a very low used level. The alkoxylated alkylamine quaternary surfactant is compatible in all salts of glyphosate formulations (including potassium and ammonium) EVEN AT VERY HIGH CONCENTRATION (470-600 g a.e./l). | 2009-08-20 |
20090209426 | HERBICIDAL MIXTURE - A mixture of diuron with mesotrione optionally containing other herbicides such hexazinone is disclosed as useful for controlling undesired vegetation. Also disclosed is a herbicidal composition comprising diuron, mesotrione and optionally other herbicides such as hexazinone and at least one additional component selected from the group consisting of surfactants, solid diluents and liquid diluents. Further disclosed is a method of controlling undesired vegetation comprising applying to the locus of the vegetation a herbicidally effective amount of the mixture. | 2009-08-20 |
20090209427 | Microbial glyphosate resistant epsps - The present invention is based, in part, on a method for the identification of glyphosate resistant 5-enolpyruvyl-3-phosphoshikimate synthase polypeptides and the isolation of the DNA molecules that encode the polypeptides. Also, chimeric DNA constructs are described that are useful to transform and express the glyphosate resistant 5-enolpyruvyl-3-phosphoshikimate synthase polypeptide in bacteria and plant cells. The invention provides chimeric DNA molecules that are useful to transform plant cells, and the transformed plants, progeny, and parts thereof regenerated from the transformed plant cells. | 2009-08-20 |
20090209428 | PRODUCTION METHOD OF Bi-2223-BASED SUPERCONDUCTING WIRE - The invention offers a method of producing a Bi-2223-based superconducting wire. The method has a preparing step for preparing a precursor | 2009-08-20 |
20090209429 | METHOD OF FORMING AN HTS ARTICLE - A method of forming a superconducting article includes providing a substrate tape, forming a superconducting layer overlying the substrate tape, and depositing a capping layer overlying the superconducting layer. The capping layer includes a noble metal and has a thickness not greater than about 1.0 micron. The method further includes electrodepositing a stabilizer layer overlying the capping layer using a solution that is non-reactive to the superconducting layer. The superconducting layer has an as-formed critical current I | 2009-08-20 |
20090209430 | TEMPLATE DIRECTED SPLIT AND MIX SYSTHESIS OF SMALL MOLECULE LIBRARIES - The present invention provides a method for combining the advantages of encoded molecule fragments made by split and mix synthesis with the advantages of template directed synthesis of molecules. The method provided in the invention comprises the steps of: Adding a linker molecule L to one or more reaction wells; Adding a molecule fragment to each of said reaction wells; Adding an oligonucleotide identifier to each of said reaction wells; Subjecting said wells to conditions sufficient to allow said molecule fragments and said oligonucleotide identifiers to become attached to said linker molecule, or conditions sufficient for said molecule fragments to bind to other molecule fragments and sufficient for said oligonucleotide identifiers to bind to other oligonucleotide identifiers; Combining the contents of said one or more reaction wells; Optionally, distributing the combined product to one or more new reaction wells; Optionally, repeating steps b) to e) one or more times; Contacting the resulting bifunctional molecule(s) of step e) or g) with one or more Contacting the resulting bifunctional molecule(s) of step e) or g) with one or more (oligonucleotide) templates each capable of hybridizing to at least one of the oligonucleotide identifiers added in step c). | 2009-08-20 |
20090209431 | Non-Invasive in Vitro Method to Detect Transitional Cell Carcinoma of the Bladder - The present invention refers to a non-invasive in vitro method to detect a transitional cell carcinoma of the bladder in an individual via urine analysis, to determine the stage or severity of this cancer in an individual or to monitor the effect of treatment administered to an individual suffering from this cancer. | 2009-08-20 |
20090209432 | Detecting targets using nucleic acids having both a variable region and a conserved region - The invention relates to nucleic acid molecules for use in detecting a target nucleic acid molecule which is a member of a class of nucleic acid molecules and which is characterised by a specific variant region, said nucleic acid molecule comprising (i) a nucleic acid stem region which comprises a nucleic acid interaction site directed to a conserved region of the class of which said target nucleic acid molecule is member, or part thereof and which conserved region is located proximally to a variant region; operate y linked to (ii) a nucleic acid recognition region comprising at least two nucleotides. The nucleic acids are used in arrays and are an efficient means of screening molecules exhibiting a unique nucleotide sequence within a randomly varying population. The invention is useful in monitoring the effectiveness of therapeutic drug therapies and the progression of medical conditions, characterised by the presence of clonal populations of cells, particularly clonal lymphocyte populations. | 2009-08-20 |
20090209433 | METHOD FOR SCREENING AND SELECTING LIGANDS - The present invention provides a method for screening of ligands wherein the target is a membrane protein, which is reconstituted into a membrane environment, using the surface plasmon resonance (SPR) technology. In particular, the target is a VDAC protein. | 2009-08-20 |
20090209434 | Probe-antiprobe compositions and methods for DNA or RNA detection - The invention provides novel compositions and methods for detecting unlabeled nucleic acid targets using labeled polynucleotide probes and partially complementary antiprobes. The interaction of probes, antiprobes and targets result in signaling changes that indicate target frequency. This novel detection mechanism is called a DNA detection switch, and it enable end-point detection, microarray detection and real-time PCR detection of a variety of nucleic acid targets including microbial species and subspecies, drug resistant mutants, and pathogenic strains. | 2009-08-20 |
20090209435 | Methods of screening for TRPM4b modulators - The invention relates, in part, to methods useful in identifying molecules, that bind TRPM4b, which modulate TRPM4b ion channel activity, and/or which alter expression of TRPM4b within cells. The TRPM4b channels as described herein contain TRPM4b polypeptides, which are in turn encoded by TRPM4b nucleic acids. The ion channels described herein are preferably formed in HEK-293 cells from one or more novel TRPM4b polypeptides, which exhibit one or more of the unique TRPM4b properties described herein. | 2009-08-20 |
20090209436 | HYDROGEL LABELED PRIMER EXTENSION METHOD FOR MICROARRAYS - A method for fabricating hydrogel based microarrays by a nanostamping process is provided. A method of manufacturing a patterned hydrogel array is provided comprising the steps of contacting a patterned substrate with a hydrogel substrate to form a substrate complex, wherein the patterned substrate comprises a surface, a first polymer attached to the surface, and a second polymer reversibly attached to the first polymer, the hydrogel substrate comprises a polymer matrix and a plurality of attachment sites along the polymer matrix capable of attaching the second polymer, binding at least one attachment site to the second polymer, disassociating the dimer; and separating the substrate complex to obtain a patterned hydrogel array having a second polymer attached to an attachment site. Methods where the second polymer is synthesized using the first polymer as template are provided. Hydrogel arrays manufactured according to the methods of the invention are provided. | 2009-08-20 |
20090209437 | TEMPERATURE REGULATED PROMOTERS FROM SCHIZOSACCHAROMYCES POMBE FOR EXPRESSION OF PROTEINS - The present invention relates to novel temperature promoters and set of expression vectors isolated from | 2009-08-20 |
20090209438 | LOW RESIDUE FLUID FRACTURING SYSTEM AND METHOD OF USE - A fluid system for hydraulic fracturing operations which comprises a low residue fluid that facilitates the clean up of the wellbore following the treatment is disclosed. The system includes a surfactant compound that forms micelles above a critical concentration. Under certain conditions the addition of an associative thickener compound yields a network based on hydrophobic interactions. The resulting viscous fluid can transport proppants, be applied neat or as a foamed or energized system, or used in an acidizing treatment. The fluid system may further include a breaker additive. | 2009-08-20 |
20090209439 | ACIDIZING TREATMENT COMPOSITIONS AND METHODS - A reservoir treatment fluid is described being a hydrochloric acid and a compound forming a carboxylic acid within a well penetrating a subterranean reservoir. | 2009-08-20 |
20090209440 | Star Polymer Lubricating Composition - The invention provides a lubricating composition containing (a) 0.1 to 15 wt % of a polymer with (i) a weight average molecular weight of 100,000 to 500,000; and (ii) a shear stability index of 10 to 60; (b) a phosphorus-containing acid, salt, or ester; (c) a dispersant; and (d) an oil of lubricating viscosity. The invention further provides a method for lubricating a mechanical device with the lubricating composition. | 2009-08-20 |
20090209441 | Maleated vegetable oils and derivatives, as self-emulsifying lubricants in metalworking - A succinated triglyceride oil derived from maleating triglyceride oil from a plant or land animal is described for use as an emulsifying agent for metalworking fluids. The metalworking fluid would comprise water; as an emulsifier this succinated triglyceride, optionally further reacted with water, Group IA and IIA metals, ammonium hydroxide, various amines, alkanolamines, alkoxylated alkanolamines, and polyamines to form a modified emulsifier; and optionally an oil and other additives. | 2009-08-20 |
20090209442 | CYCLIC PHOSPHAZENE COMPOUND - A cyclic phosphazene compound complying with formula (I) or (II): | 2009-08-20 |
20090209443 | ANTIMICROBIAL HAND WASH - An antimicrobial hand wash includes a soap, an antimicrobial agent, and an amine salt. The amine salt is found to increase the antimicrobial efficacy of the hand wash. The amine salt produced through the reaction of monoethanolamine and lactic acid is of particular interest as a soap addition. In processes of this invention, it is possible to create the desired amine salt in the soap in situ. | 2009-08-20 |
20090209444 | Instrument for cleaning and aluminum workpiece - A method of conditioning the surface of a work piece, in particular of a litho-strip or litho-sheet, consisting of an aluminum alloy enables an increase in manufacturing speed in surface roughening while maintaining a high quality of the electro-chemical grained surface of the work piece with relative low effort related to facility equipment. The method of conditioning comprises at least the step of degreasing the surface of the work piece with a degreasing medium, wherein the degreasing medium contains at least 1.5 to 3% by weight of a composite of 5-40% sodium tripolyphosphate, 3-10% sodium gluconate, 3-8% of a composite of non-ionic and anionic surfactants and optionally 0.5 to 70% soda, wherein sodium hydroxide is added to the degreasing medium such that the concentration of sodium hydroxide in the aqueous degreasing medium is 0.01 to 5% by weight. | 2009-08-20 |
20090209445 | LIQUID TREATMENT UNITIZED DOSE COMPOSITION - According to the present invention there is provided a pearlescent unitary dose composition comprising a water-soluble film encapsulating a liquid treatment composition suitable for use as a laundry or hard surface cleaning composition having turbidity of greater than 5 and less than 3000 NTU, said composition comprising a pearlescent agent and from 2% to 15% by weight of the composition of water. | 2009-08-20 |
20090209446 | BLEACH COMPOSITIONS - Laundry or cleaning composition comprising: (a) a catalytically effective amount, preferably from about 1 ppb to about 99.9%, of a transition-metal bleach catalyst which is a complex of a transition-metal and a cross-bridged macropolycyclic ligand; and (b) at least about 0.1% of one or more laundry or cleaning adjunct materials, preferably comprising an oxygen bleaching agent. Preferred compositions are laundry compositions and automatic dishwashing detergents which provide enhanced cleaning/bleaching benefits through the use of such catalysts. | 2009-08-20 |
20090209447 | CLEANING COMPOSITIONS - The present application relates to nil phosphate and nil borate cleaning compositions comprising a protease cleaning system and a wetting agent, and processes for making and using such compositions. Such compositions offer improved enzyme stability in product and a consumer desirable cleaning profile. | 2009-08-20 |
20090209448 | COMPOSITION FOR REMOVING MINERAL DEPOSITS AND ETCHING FROM HARD SURFACES - A composition and for removing mineral deposits and method of making the composition is provided which includes water, a fine abrasive, a plurality of petroleum distillate products, at least one polyalcohol, at least one fatty acid, at least one non-ionic surfactant and at least one semipolar solvent. Water is present at about 20-50 wt %, abrasive particles at about 10-35 wt %, petroleum distillates at about 10-35 wt %, polyalcohol at about 0.5-5 wt %, fatty acid at about 0.5-5 wt %, non-ionic surfactant at about 1-3 wt %, and semipolar solvent at about 0.1-1 wt %. A method of removing mineral deposits from a hard surface such as glass is provided which includes applying the aforesaid composition to a hard surface and removing the composition from the surface to remove mineral deposits from the surface. | 2009-08-20 |
20090209449 | NOVEL WOODY ODORANTS - The present invention relates to novel substituted cyclohexyl monohydric alcohols possessing woody odor which are useful as fragrance materials. The invention also provides method for synthesis of the above compounds. The invention also provides fragrance compositions which utilize the compounds of the invention to impart woody aroma to such compositions. | 2009-08-20 |
20090209450 | MicroRNA Fingerprints During Human Megakaryocytopoiesis - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of cancer and myeloproliferative disorders. The invention also provides methods of identifying anti-cancer agents. | 2009-08-20 |
20090209451 | HETEROARYLAMINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES - The present invention relates to heteroarylaminopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders. | 2009-08-20 |
20090209452 | SUBSTANTIALLY PURE GLYCOPEPTIDE ANTIBIOTICS AC-98-1; AC-98-2; AC-98-3; AC-98-4 AND AC-98-5 - The invention provides new substantially pure antibiotics designated AC-98-1, AC-98-2, AC-98-3, AC-98-4 and AC-98-5 derived from the microorganism | 2009-08-20 |
20090209453 | Glycoprotein Hormone Analogs - This invention relates to the field of glycoprotein hormone analogs and their uses as agonists, antagonists, targeting vectors, and immunogens. In particular, this invention describes a method for stabilizing a heterodimer that permits the preparation of functional glycoprotein hormone analogs. The analogs of present invention comprise at least one alpha subunit polypeptide and at least one beta subunit polypeptide, wherein the seatbelt region of the beta subunit is linked to the alpha subunit. The invention also provides for a beta subunit polypeptide wherein the C-terminal amino acid is from residue 10 to residue 20 of the seatbelt region. | 2009-08-20 |
20090209454 | METHOD FOR PURIFYING FSH OR A FSH MUTANT - The invention relates to a method for purifying a glycoprotein, preferably FSH or a FSH mutant comprising the steps of subjecting a liquid containing said FSH or a FSH mutant to: (1) a dye affinity chromatography; (2) a weak anion exchange chromatography; (3) a hydrophobic interaction chromatography; and (4) a strong anion exchange chromatography; which may be carried out in any order. | 2009-08-20 |
20090209455 | VITREOUS ADMINISTRATION OF ERYTHROPOIETIN - A therapeutic composition for treating and/or preventing retinal disorder includes intravitreally or transsclerally administered erythropoietin. | 2009-08-20 |
20090209456 | COMPOSITIONS AND METHODS FOR IMPROVING FACIAL AND BODY AESTHETICS - Compositions and methods of treating facial and body tissue aesthetics and reconstruction are disclosed using immunosuppressive agents either by themselves or in conjunction with other soft tissue fillers. | 2009-08-20 |
20090209457 | TREATMENT OF ANTI-ERYTHROPOIETIN ANTIBODY-MEDIATED DISORDERS WITH SYNTHETIC PEPTIDE-BASED EPO RECEPTOR AGONISTS - The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat or to prevent anti-erythropoietin (EPO) antibody-mediated disorders such as pure red cell aplasia (PRCA) that are characterized by anti-EPO antibodies. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided. | 2009-08-20 |
20090209458 | Cell-penetrating socs polypeptides that inhibit cytokine-induced signaling - Disclosed are compositions and methods related to cell-penetrating suppressor of cytokine signaling (SOCS) proteins that inhibit cytokine-induced signaling. | 2009-08-20 |
20090209459 | Method of Treating Myasthenia Gravis - The invention relates to the use of agents that bind the complement protein C5 in the treatment of diseases associated with inappropriate complement activation and in particular in the treatment of myasthenia gravis. | 2009-08-20 |
20090209460 | COMPOSITIONS AND METHODS FOR TREATING OBESITY AND RELATED METABOLIC DISORDERS - The present invention relates to the use of neuromedins in methods to treat and prevent conditions such as obesity and other food-related disorders. In addition, novel peptides, FNX Peptides, are provided, which find use in treating these disorders. | 2009-08-20 |
20090209461 | MODIFICATION OF FEEDING BEHAVIOR - Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering a therapeutically effective amount of PYY or an agonist thereof to the subject, thereby decreasing the calorie intake of the subject. | 2009-08-20 |
20090209462 | REGULATION OF FUNCTION OF ANGIOPOIETIN - Pharmaceutical compositions that comprise a pharmaceutically acceptable carrier and either a therapeutically effective amount of an ECM-binding fragment of Ang-1 protein at comprises SEQ ID NO:1 and/or SEQ ID NO:2 or a homologous peptide thereof and pharmaceutical compositions that comprise a pharmaceutically acceptable carrier and a vector comprising a nucleic acid molecule that comprises the nucleotide sequence that encodes an ECM-binding fragment of Ang-1 protein that comprises SEQ ID NO:1 and/or SEQ ID NO:2 or a homologous peptide thereof are disclosed. Methods of using such compositions to treat individuals suspected of having coronary artery disease, vascular disease or a condition involving ischemia and to promote angiogenesis, endothelial survival and maintaining vascular integrity are disclosed. Methods to identify compounds that modulates binding of Ang-1 to ECM are disclosed. Pharmaceutical compositions which comprise a therapeutically effective amount of Ang-2 protein and/or a vector comprising a nucleic acid molecule that comprises the nucleotide coding sequence of Ang-2 and methods of using such compositions to treat individuals suspected of having cancer are disclosed. | 2009-08-20 |
20090209463 | Hgf Precursor Protein Variant and Active Protein Thereof - An HGF precursor protein variant, in which a peptide structure comprises a sequence including a peptide chain X inserted between an α chain of HGF or a polypeptide where 1 to 20 amino-acid residues from the C-terminus of the α chain are deleted, and a β chain of HGF or a polypeptide where 1 to 20 amino-acid residues from the N-terminus of the β chain are deleted; wherein (i) the peptide chain X has an amino-acid sequence of at least two residues, (ii) the peptide chain X can be cleaved by a protease reaction or a chemical reaction, and (iii) a protein obtained by cleaving at least one site of the peptide chain X has HGF action. | 2009-08-20 |
20090209464 | Flavivirus fusion inhibitors - The present invention relates to peptides and methods of inhibiting fusion between the virion envelope of Flaviviruses and membranes of the target cell, the process that delivers the viral genome into the cell cytoplasm. The invention provides for methods which employ peptides or peptide derivatives to inhibit Flavivirus:cell fusion. The present invention is based in part on the discovery that E1 envelope glycoprotein of hepaciviruses and E2 envelope glycoprotein of pestivirus have previously undescribed structures, truncated class II fusion proteins. The present invention provides peptides and methods of treatment and prophylaxis of diseases induced by Flaviviruses. | 2009-08-20 |
20090209465 | MCT1 Transporters Expressed in Blood Brain Barrier Cells - MCT1 is consistently expressed at high levels in brain microvessel endothelial cells. Disclosed herein are assays for determining whether a test material/molecule is a substrate for, and/or is actively transported by, the MCT1 transporter, and therefore a candidate substrate for crossing the blood brain barrier. The assays are useful in screening for therapeutic, cytotoxic or imaging compounds used in the treatment or diagnosis of neurological diseases. | 2009-08-20 |
20090209466 | PEPTIDES WITH ANTI-PROLIFERATIVE ACTIVITY - The present invention relates to peptides with anti-proliferative activity, of sequence SEQ ID No. 1, SEQ ID No. 2 or SEQ ID No. 3. | 2009-08-20 |
20090209467 | VIRAL CAPSID PROTEINS AND ANY PEPTIDES OR COMPOSITIONS THEREOF FOR THE TREATMENT OF PATHOLOGIC DISORDERS - The present invention relates to viral capsid proteins, as a medicament for the treatment of a pathologic disorder. More particularly, the invention relates to the viral capsid proteins VP1, VP2 and VP3, preferably, the SV40 VP1 or any peptide, fragment, mutant, derivative and mixtures thereof or of virus-like particles (VLP's) comprising the same, as the active ingredient in compositions for the treatment of pathologic disorders, preferably disorders associated with inactivation of cellular proteins involved with quality control processes, particularly, chaperones. The invention further provides methods for the treatment of such disorders and the use of the SV40 capsid proteins for the preparation of pharmaceutical compositions. | 2009-08-20 |
20090209468 | Alpha-neurotoxin proteins with anti-inflammatory properties and uses thereof - The invention provides methods and compositions for treating arthritic conditions such as osteoporosis and rheumatoid arthritis. The treatment methods include administering an effective amount of a pharmaceutical composition comprising an isolated alpha-neurotoxin protein, or an effective variant or fragment thereof. The compositions are effective for decreasing the levels of pro-inflammatory cytokines and increasing the level of interleukin-10 in a subject with arthritis, and can reduce symptoms of the arthritic condition including edema, infiltration of inflammatory cells and pannus formation in affected joints. In some preferred embodiments of compositions in accordance with the invention, the effective therapeutic protein is an alpha-neurotoxin protein isolated from snake venom, or a recombinant or synthetic protein based on, or derived from, the amino acid of sequence of an alpha-neurotoxin protein isolated from snake venom. Some preferred alpha-neurotoxin proteins are derived from the venom of elapid snakes including | 2009-08-20 |
20090209469 | Use of Exendins and GLP-1 Receptor Agonists for Altering Lipoprotein Particle Size and Subclass Composition - The present invention relates to altering the concentration of various lipid molecules, specifically for example by shifting from small LDL particles to large LDL and HDL particles. The present invention also relates to methods for increasing average lipid particle size and methods for improving the cardiovascular risk profile of a subject by altering lipid particle sizes or concentrations or both. | 2009-08-20 |
20090209470 | T24 ANTIGEN FOR IMMUNODIAGNOSIS OF TAENIA SOLIUM CYSTICERCOSIS - The present disclosure relates to T24 nucleic acid sequences, amino acid sequences, and antibodies. Methods for detecting and diagnosing | 2009-08-20 |
20090209472 | AMIDE AND PEPTIDE DERIVATIVES OF DIALKYLENETRIAMINES AND THEIR USE AS TRANSFECTION AGENTS - This invention relates to newly identified spermidine based surfactant compounds, to the use of such compounds and to their production. The invention also relates to the use of the spermidine based compounds to facilitate the transfer of polynucleotides into cells. | 2009-08-20 |
20090209473 | Componds and methods for pormoting angiogenesis - Angiogenesis may be initiated or increased through the use of gamma-secretase inhibitors. The gamma-secretase inhibitor can be a dipeptide class, sulfonamide class, transition state mimic class, benzodiazepine class, or benzocaprolactam class gamma secretase inhibitor. Methods for initiating and increasing angiogenesis are used for disease prevention and treatment as well as for generating research models. | 2009-08-20 |
20090209474 | NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE - The present invention relates to novel therapeutic uses of tianeptine, salts, isomers, pro-drugs, metabolites and structural analogs thereof. Furthermore, the present invention relates to the use of tianeptine, salts, isomers, pro-drugs, metabolites and structural analogs thereof, in obtaining methods of screening and of developing drugs. Finally, the present invention relates to the novel therapeutic use of other glutamine synthetase (GS) ligands and to the use of these ligands in obtaining methods for screening and developing drugs. | 2009-08-20 |
20090209475 | Sulfonated sugar compounds, pharmaceutical compositions which contain the same, and methods of treating tumors with the same - Sulfoquinovosylacyl propanediol compounds represented by formula (I): | 2009-08-20 |
20090209476 | PESTICIDAL COMPOSITIONS - The invention disclosed in this document is related to the field of pesticides and their use in controlling pests. A compound having the following structure is disclosed. | 2009-08-20 |
20090209477 | AZACYTIDINE ANALOGUES AND USES THEREOF - The present invention is directed toward compounds of Formula (I) as follows: | 2009-08-20 |
20090209478 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE HAMP GENE - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the HAMP gene (HAMP gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of the HAMP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by HAMP gene expression and the expression of the HAMP gene using the pharmaceutical composition. | 2009-08-20 |
20090209479 | THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS - Aspects of the invention include 2′ protected nucleoside monomers that are protected at the 2′ site with thiocarbon protecting groups. Thiocarbon protecting groups of interest include thiocarbonate, thionocarbonate, dithiocarbonate groups, as well as thionocarbamate protecting groups. Aspects of the invention further include nucleic acids that include the protecting groups of the invention, as well as methods of synthesizing nucleic acids using the protecting groups of the invention. | 2009-08-20 |
20090209480 | CENTRAL ADMINISTRATION OF STABLE FORMULATIONS OF THERAPEUTIC AGENTS FOR CNS CONDITIONS - The present invention concerns compositions, methods and/or apparatus of central administration of various CNS-active agents. In particular embodiments, intrathecal administration is advantageous for decreasing the systemic concentrations of CNS agent, thereby decreasing side effect toxicity, while allowing more effective delivery of the agent to the site of action, simultaneously decreasing the dosage delivered to the subject. In particular embodiments, ICV delivery may be of use for patients who have previously proven to be refractory to systemic administration of CNS agents, in some cases due to systemic side effects, or for those patients whose symptoms are of sufficient severity to warrant more aggressive therapeutic intervention. ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS. | 2009-08-20 |
20090209481 | Nucleoside prodrugs and uses thereof - Compounds having the formula I or II wherein R | 2009-08-20 |
20090209482 | AZACYTIDINE ANALOGUES AND USES THEREOF - The present invention is directed toward compounds of Formula (I) as follows: | 2009-08-20 |
20090209483 | TREATMENTS FOR FLAVIVIRIDAE VIRUS INFECTION - The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host. | 2009-08-20 |
20090209484 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR CALCIPENIA - The invention is to develop an agent having at least one of anricalclpenic, antiedemic and diuretic activities for humans or animals and to inhibit the postpartum drop of the calcium concentration in blood, thereby maintaining the health of the mother body and smoothing nursing and lactation. | 2009-08-20 |
20090209485 | MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES - This invention relates to the use of Nod factors and derivatives thereof for the modulation of blood vessel growth and development as well as compositions for modulating angiogenesis. | 2009-08-20 |
20090209486 | Compositions of carbohydrates as dietary supplements - In accordance with the present invention, there is to provide a dietary supplement that provides humans and animals with the essential carbohydrates needed to maintain proper health and functionality, to fend off illness, act as viral inhibitors, lessen the aging process of cells and to provide pets with another level of medications equal to that for humans. | 2009-08-20 |
20090209487 | Compositions of carbohydrates as dietary supplements - In accordance with the present invention, there is to provide a dietary supplement that provides a mammal with the essential carbohydrates needed to maintain proper health and functionality, to fend off illness, lessen the aging process of cells and to provide pets with another level of medications equal to that for humans. | 2009-08-20 |
20090209488 | Compositions for the treatment of exercise induced asthma - In accordance with the present invention, there is to provide a dietary supplement that provides a mammal with the essential carbohydrates needed to maintain proper health and functionality, to fend off illness, to provide an alternative treatment for exercise induced asthma and asthma related illnesses, to lessen the aging process of cells and to provide pets with another level of medications equal to that for humans. | 2009-08-20 |
20090209489 | Compositions for the treatment of diabetis, system PH disorders, high blood pressure, and a cancer marker system - In accordance with the present invention, there is to provide a dietary supplement that provides a mammal with the essential carbohydrates needed to maintain proper health and functionality, to fend off illness, to restore proper system pH, to provide a new treatment for pH based illnesses, to provide a new marker system for the early detection of cancer, to provide a new treatment for borderline diabetics, to provide a new treatment for high blood pressure, to lessen the aging process of cells and to provide pets with another level of medications equal to that for humans. | 2009-08-20 |
20090209490 | DISINFECTANT COMPOSITION - Disinfectant composition comprising slightly acidic electrolyzed water and 0.001-1.0 wt % of a polyether-modified silicone of formula (1) or formula (2) | 2009-08-20 |
20090209491 | Lactams as conformationally constrained peptidomimetic inhibitors - The present invention relates to inhibitors of post-proline cleaving enzyme, such as inhibitors of dipeptidyl peptidase IV, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. In particular, the inhibitors of the present invention incorporate a lactam ring in the backbone of the inhibitors. The compounds of the present invention can have a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the target protease. | 2009-08-20 |
20090209492 | Lipase Inhibitors - The present invention relates to inhibitors of lipases, such as inhibitors of endothelial lipase, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. The prototype of these inhibitors has lipophilic portion and an electrophilic site. | 2009-08-20 |
20090209493 | COMBINATION THERAPY COMPRISING A BISPHOSPHONATE AND A HMG-COA REDUCTASE INHIBITOR - A pharmaceutical composition for treatment of malignancies, in particular multiple myeloma (MM), comprises in combination a bisphosphonate, e.g. zoledronic acid or a salt or ester, and an HMG-CoA reductase inhibitor for simultaneous, sequential or separate use. Also provided is a method of treating a patient suffering from a malignant disease comprising administering to the patient an effective amount of a bisphosphonate and an effective amount of an HMG-CoA reductase inhibitor. | 2009-08-20 |
20090209494 | 21-DEOXYMACBECIN ANALOGUES USEFUL AS ANTITUMOR AGENTS - The present invention relates to 21-deoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and or prophylaxis of cancer or B-cell malignancies. | 2009-08-20 |
20090209495 | USE OF EDG RECEPTOR BINDING AGENTS IN CANCER - Provided is a method for treating solid tumors, e.g. tumor invasiveness, and particularly inhibiting or controlling deregulated angiogenesis, using a sphingosine- | 2009-08-20 |
20090209496 | METHODS AND COMPOSITIONS FOR ENHANCING THE EFFICACY OF RTK INHIBITORS - This invention relates to methods for treating, preventing and/or managing cancer in a subject including enhancing the efficacy of a Receptor Tyrosine Kinase inhibitor (e.g., a small molecule RTK inhibitor, e.g., Sorafenib or Erlotinib) by administering to the subject a Vascular Disrupting Agent (e.g., a Combretastatin or derivative thereof) sequentially or simultaneously in combination with said RTK inhibitor. Pharmaceutical compositions comprising a combination of a RTK inhibitor and a VDA are also provided. | 2009-08-20 |
20090209497 | METHOD OF TREATING LYMPHANGIOLEIOMYOMATOSIS (LAM) - The invention provides a method for the treatment of Lymphangioleiomyomatosis (LAM) in the human subject in need thereof. The method comprises administering to the subject an effective amount of doxycycline or a salt thereof. The invention further provides a method for monitoring the efficacy of treatment. Treatment efficacy is monitored by measuring MMP levels. Reduction in MMP levels indicates that the treatment is effective. | 2009-08-20 |
20090209498 | Methods of Treatment Using CCA1 Inhibitors - Provided herein are methods for the treatment or prevention of a fungal infection in a host comprising the administration to the host a therapeutically or prophylactically effective amount of a CCA1 inhibitor. | 2009-08-20 |
20090209499 | Apiary veterinary composition - The present invention concerns veterinary compositions for the treatment and/or prevention of nosema disease ( | 2009-08-20 |
20090209500 | USE OF VITAMIN D RECEPTOR AGONISTS AND PRECURSORS TO TREAT FIBROSIS - This application relates to methods of treating, preventing, and ameliorating fibrosis, such as fibrosis of the liver, kidney, or pancreas. In particular, the application relates to methods of using a vitamin D receptor agonist (such as vitamin D, vitamin D analogs, vitamin D precursors, and vitamin D receptor agonists precursors) for the treatment of fibrosis. Also disclosed are methods for screening for agents that treat, prevent, and ameliorate fibrosis. | 2009-08-20 |
20090209501 | METHOD OF TREATING AND PREVENTING SECONDARY HYPERPARATHYROIDISM - The a method of treating elevated blood levels of iPTH by increasing or maintaining blood concentrations of both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in a patient by administering, as necessary, both Vitamin D repletion and Vitamin D hormone replacement therapies, is disclosed. The blood concentrations of 25-hydroxyvitamin D are increased to and maintained at or above 30 ng/mL, and blood concentrations of 1,25-dihydroxyvitamin D are increased to or maintained within a patient's normal historical physiological range for 1,25-dihydroxyvitamin D without causing substantially increased risk of hypercalcemia, hyperphosphatemia or over suppression of plasma iPTH in the patient. The blood levels of 25-hydroxyvitamin D are maintained at or above 30 ng/mL between doses of Vitamin D repletion therapies, and the blood levels of 1,25-dihydroxyvitamin D are maintained in the patient's normal historical physiological range between doses of Vitamin D hormone replacement therapies. In one aspect, the disclosure includes methods wherein the blood concentration of 25-hydroxyvitamin D during treatment comprises predominantly 25-hydroxyvitamin D | 2009-08-20 |