34th week of 2018 patent applcation highlights part 38 |
Patent application number | Title | Published |
20180238847 | METHOD FOR EVALUATING EXHAUST GAS SIMULATION - Evaluation method of exhaust gas simulation capable of simply and appropriately evaluating the validity of the simulation is provided. In analysis data, an analysis amplitude curve is calculated in which a change in the concentration of virtual exhaust gas at the observation point in the converged pipe portion is plotted, and an analysis time interval between the zero point and the reference point in the analysis amplitude curve is plotted. In actual measurement data, an actual amplitude curve is provided in which a change in the specific gas component at an observation point is measured with time, and an actual time interval is provided in which a time interval from a zero point to a reference point in the actual amplitude curve. The analysis data is determined as valid when a difference between the analysis time interval and the actual time interval is within a predetermined correlation range. | 2018-08-23 |
20180238848 | SYSTEM AND METHOD FOR DETERMINATION OF UNUSABLE PRODUCTS - A credibility weight for each of a plurality of users is stored and is associated with a reliability of the user in accurately indicating whether the products have become spoiled. Images of a plurality of products at a retail store are received and electronically arranged in an organized pattern. The organized pattern is rendered onto selected ones of a plurality of display devices. Electronic choices from selected ones of the plurality of the users are received. Each of the electronic choices indicates for a selected one of the plurality of products whether the selected user believes the selected product has spoiled or has become unusable. A spoilage score for each product of the products is determined. A control signal is transmitted to a receiver circuit at the retail store instructing a human or robot to perform an investigation when the spoilage score exceeds a predetermined threshold. | 2018-08-23 |
20180238849 | RAPID TEST FOR BACTERIA - The invention relates to methods and devices for quantitative determination of bacteria. | 2018-08-23 |
20180238850 | DETECTION METHOD - A method of analysis of a hydrocarbon fuel for the presence of a micro-organism comprises contacting a fuel sample with an aqueous diluent and with an antibody reactive with the micro-organism, or reactive with a metabolite of breakdown product produced by the micro-organism, to detect the presence or absence of the micro-organism. | 2018-08-23 |
20180238851 | METHOD AND SYSTEM OF CONDITION MONITORING - A condition monitoring system that determines a presence of change of water content in grease. The system provides a sensor electrode that is placed in the space where the grease is located. The electrode is suitably a plate with a surface area creating a capacitance C. This in combination with a resistor R, creates an RC circuit. The system senses the RC circuit. The dielectric constant of the monitored grease varies in dependence of the water content of the grease. A change of the dielectric constant will change RC, that is then sensed by the system. An analysis of a change of RC will determine if there is a presence of a change of the level of water content in the monitored grease. | 2018-08-23 |
20180238852 | METHOD AND DEVICE FOR DETERMINING THE TEMPERATURE AND HUMIDITY OF A BUILDING - The invention relates to a method and a device for determining the temperature and moisture of a structure, having at least one temperature sensor and at least one moisture sensor, wherein a water-vapor diffusion-impermeable volume is formed on the surface of the structure, and, after reaching a state of equilibrium, the temperature and moisture is measured with the at least one temperature sensor and the at least one moisture sensor in the water-vapor diffusion-impermeable volume, and used for determining the temperature and moisture in the structure. According to the present invention, the water-vapor-diffusion equivalent air layer thickness of the water-vapor diffusion-impermeable volume is at least 1000 m, and the temperature and moisture of the ambient air are measured. | 2018-08-23 |
20180238853 | METHODS AND SYSTEMS FOR MEASURING THE FORCES OF A SHRINK FILM - According to one embodiment described herein, the forces of a shrink film may be measured. The method of measuring the forces may include providing a shrink film processing unit and a testing vehicle moveable within the shrink film processing unit, positioning a shrink film around the testing vehicle, processing the wrapped testing vehicle by shrinking the shrink film around the testing vehicle as the testing vehicle moves through the shrink film processing unit, and measuring the forces applied by the shrink film on the testing vehicle with one or more force sensors at multiple separate sensor positions on the exterior of the testing vehicle during processing, after processing, or both. | 2018-08-23 |
20180238854 | OPERATION AND VERIFICATION OF A PORTABLE CLINICAL ANALYSIS SYSTEM - The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof. | 2018-08-23 |
20180238855 | METHOD FOR IN-LINE MEASUREMENT OF QUALITY OF MICROARRAY - A method for in-line measurement of the quality of a microarray are disclosed and the method includes the following steps. A solid substrate is provided, and the solid substrate includes a plurality of areas in an array. At least one biomarker is in-situ synthesized on at least one of the plurality of areas by a plurality of synthesis steps. After performing at least one of the plurality of synthesis step, a check step is immediately performed on a semi-product of the at least one biomarker by an atomic force microscope to obtain an in-line measurement result. The quality of the semi-product of the at least one biomarker is determined based on the in-line measurement result. | 2018-08-23 |
20180238856 | APPARATUS FOR DETERMINING VISCOELASTIC CHARACTERISTICS OF AN OBJECT, AND METHOD THEREOF - Disclosed is an apparatus for determining viscoelastic characteristics of at least a portion of an object. The apparatus comprises a fluidly sealable housing, comprising at least one aperture and at least one fluid inlet port and at least one resilient membrane that is operatively coupled to the housing so as to sealingly engage with the at least one aperture. The apparatus further comprises at least one actuator that is operatively coupled to the at least one inlet port and adapted to actuate the at least one resilient membrane via a working fluid that is contained within the housing, so that the at least one resilient membrane is moved towards and into engagement with at least a portion of an object at a predetermined pressure. Furthermore, the apparatus comprises at least one first sensor that is operably coupled to the membrane and that is adapted to determine at least a deformation of the at least one resilient membrane during actuation. | 2018-08-23 |
20180238857 | ELECTRIC-FIELD IMAGER FOR ASSAYS - This disclosure describes an electric-field imaging system and method of use. In accordance with implementations of the electric-field imaging system, a fluid sample can be placed on top of a pixel-based impedance sensor. An image of the target analytes can be created immediately afterwards. From this image, computer imaging algorithms can determine attributes (e.g., size, type, morphology, volume, distribution, number, concentration, or motility, etc.) of the target analytes. | 2018-08-23 |
20180238858 | METHOD AND DEVICE FOR ASSIGNING A BLOOD PLASMA SAMPLE - A device and method for assigning a blood plasma sample to a class from a predetermined set of classes are presented. The set of classes comprises a good class, a lipemic class, a hemolytic class and an icteric class. For assignment to one of the classes, the blood plasma sample is exposed to light and measurement values dependent on transmitted or scattered light power are evaluated in order to carry out an assignment. | 2018-08-23 |
20180238859 | PREDICTIVE METHOD FOR CHARACTERIZING THE SENSITIVITY OF A TUMOUR IN RESPONSE TO A DNA-BREAKING TREATMENT - A predictive method of cellular, tissue and clinical radiosensitivity, which is based on the determination and cross-checking of a plurality of cellular and enzymatic parameters and criteria applied to a tumor response. The predictive method characterizes the sensitivity of a tumor in response to a DNA-breaking radiotherapy treatment. | 2018-08-23 |
20180238860 | INDIVIDUAL METHOD PREDICTIVE OF THE DNA-BREAKING GENOTOXIC EFFECTS OF CHEMICAL OR BIOCHEMICAL AGENTS - A predictive method of cell toxicity after exposure to chemical elements breaking DNA directly or indirectly (particularly certain metals, pesticides and certain active substances for chemotherapy) and which is based on the determination and cross-checking of a plurality of cellular and enzymatic parameters and criteria. | 2018-08-23 |
20180238861 | METHODS FOR ENHANCING THE SPECIFIC UPTAKE OF BOTULINUM NEUROTOXINS INTO CELLS - The present invention provides a method for enhancing the specific uptake of a neurotoxin polypeptide into cells, the method comprising: incubating cells susceptible to neurotoxin intoxication with a neurotoxin polypeptide for a time and under conditions which allow for the neurotoxin polypeptide to exert its biological activity, the incubation comprising at least one of the following steps: (i) K | 2018-08-23 |
20180238862 | METHODS AND SYSTEMS FOR MEASURING GROWTH RATE IN PLANT OR AQUATIC ANIMAL SPECIES - Method and systems for measuring growth rate in plant or aquatic animal species such as embryonic or adult fish. The methods and systems utilize the measurement of NADH | 2018-08-23 |
20180238863 | CHEMICAL SYNTHESIS - Herein are described methods of chemical synthesis. | 2018-08-23 |
20180238864 | MODULAR POINT-OF-CARE DEVICES, SYSTEMS, AND USES THEREOF - The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications. | 2018-08-23 |
20180238865 | DIGITAL IMMUNOASSAY - Methods of detecting an analyte in a sample are provided. In one embodiment, the method comprises forming a partition comprising the sample, a binding agent capable of emitting a signal when bound to the analyte, and a marker capable of identifying the partition; allowing the binding agent to bind to the analyte, if present; and detecting the presence of the analyte in the sample by detecting the signal emitted from the binding agent in the partition. | 2018-08-23 |
20180238866 | SUPPRESSION OF SPLA2-INTEGRIN BINDING FOR TREATING AN INFLAMMATORY CONDITION OR SUPPRESSING CELL PROLIFERATION - The present invention relates to the discovery that a secretory phospholipase A2 (sPLA2-IIA) plays an active role in mediating cellular signaling leading to an inflammatory response or cell proliferation by way of its specific binding with integrin β at site 2 of integrin β. More specifically, the invention provides a method for identifying inhibitors of inflammatory or proliferative signaling by screening for compounds that interrupt the specific binding of sPLA2 and integrin β at site 2. The invention also provides the novel use of a substance that suppresses the specific binding between sPLA2 and site 2 of integrinβ for the purpose of treating or preventing a condition involving an undesired inflammatory response or cell proliferation. | 2018-08-23 |
20180238867 | DETECTION DEVICE AND TARGET DETECTION METHOD USING THE SAME - The present invention provides a new detection device and a target detection method using the same.
| 2018-08-23 |
20180238868 | CORE-SHELL NANOPARTICLES WITH MULTIPLE CORES AND METHOD FOR FABRICATING THEM - The present invention is directed toward core-shell nanoparticles, each comprising a ligand-capped metal shell surrounding a plurality of discrete, nonconcentric, metal-containing cores. Methods of making and using these nanoparticles are also disclosed. | 2018-08-23 |
20180238869 | USES OF SYSTEMS WITH DEGREES OF FREEDOM POISED BETWEEN FULLY QUANTUM AND FULLY CLASSICAL STATES - Disclosed herein are systems and uses of systems operating between fully quantum coherent and fully classical states. Such systems operate in what is termed the “Poised realm” and exhibit unique behaviors that can be applied to a number of useful applications. Non-limiting examples include drug discovery, computers, and artificial intelligence | 2018-08-23 |
20180238870 | IMMUNOLOGICAL MEASUREMENT DEVICE - An immunological measurement device includes a micro fluid device. The micro fluid device includes a flowpath to move a specimen that is subjected to an immunological measurement by an antigen-antibody reaction; and a labeling reagent supplier that is disposed in an upstream section of the flowpath and labels the specimen. The flowpath includes a detection flowpath that is disposed downstream of the labeling reagent supplier and measures the antigen-antibody reaction of the specimen. The labeling reagent supplier includes a labeling reagent that labels the specimen by the antigen-antibody reaction, and the labeling reagent includes a labeling substance in which an antigen or an antibody is solidified. | 2018-08-23 |
20180238871 | REAGENT AND METHOD FOR MEASURING THROMBIN-ANTITHROMBIN COMPLEX - Provided is a reagent for assaying a thrombin-antithrombin complex (TAT) in a blood sample from a subject by latex agglutination assay. The reagent includes a polycation. As a result, TAT complexes can be precisely assayed while circumventing the effect of heparin. The polycation is, for example, hexadimethrine bromide, chitosans, modified dextran, aminodextran, hydroxymethyl cellulose trimethylamine, lysozyme, spermine, spermidine, polylysine, polyarginine, polyornithine, protamine sulfate, hydroxyethyl cellulose trimethylamine, heparin-binding protein, polyallylamine, polyallylamine hydrochloride, poly(diallyl dialkyl amine), polyamideamine, polyamine, polyvinylbenzyltrimethylammonium chloride, polydiallyldimethylammonium chloride, polyethyleneimine, polypropyleneimine, polypropylethyleneimine, polyimidazoline, polyvinylamine, polyvinyl pyridine, poly(acrylamide/methacryloxypropyltrimethylammonium bromide), poly(diaryldimethylammonium chloride/N-isopropylacrylamide), poly(dimethylaminoethyl acrylate/acrylamide), poly(dimethylaminoethyl methacrylate), polydimethylaminoepichlorohydrin, polyethyleneiminoepichlorohydrin, polymethacryloxyethyl-trimethylammonium bromide, hydroxypropylmethacryloyloxyethyl dimethyl ammonium chloride, poly(methyldiethylaminoethylmethacrylate/acrylamide), poly(methyl/guanidine), polymethylvinylpyridinium bromide, poly(vinylpyrrolidone-dimethylaminoethyl methacrylate), or polyvinylmethylpyridinium bromide. | 2018-08-23 |
20180238872 | IMMUNOASSAY CARTRIDGE - An immunoassay cartridge is disclosed that can enhance the reliability of an antigen-antibody reaction while increasing a speed of an antigen-antibody reaction. An immunoassay cartridge includes a reaction chamber and a fluorescence sensor assembly. A plurality of antibodies or antigens is attached to an inner surface including a bottom surface of the reaction chamber closest to the sensor. The fluorescence sensor assembly is disposed on a bottom surface of the reaction chamber. Since the bottom surface of the reaction chamber and the upper surface of the fluorescence sensor assembly are arranged to coincide with each other, even if fluid is repeatedly moved in a first direction after the fluid moves in a second direction in the reaction chamber and then moved in the first direction, there is no obstacle in the movement of the fluid. Thus, it is possible to increase the probability of antigen-antibody reaction in the reaction chamber. | 2018-08-23 |
20180238873 | DIAGNOSIS OF SYSTEMIC LUPUS ERYTHEMATOSUS USING PROTEIN, PEPTIDE AND OLIGONUCLEOTIDE ANTIGENS - Methods and kits for diagnosing or monitoring systemic lupus erythematosus (SLE) in a subject are provided. Particularly, provided is a specific antibody reactivity profile useful in diagnosing or monitoring SLE in a subject. | 2018-08-23 |
20180238874 | PROTEINS USED FOR THE DIAGNOSIS OF LYME BORRELIOSIS - Chimera proteins includlng: (i) at least one sequence of a DbpA protein of a | 2018-08-23 |
20180238875 | CIRCULATING ASTROCYTES AND MFSD2A AS BIOMARKERS - The invention provides the use of circulating astrocytes (cAstr) and the Major Facilitator Superfamily Domain containing Protein 2a (Mfsd2a) as biomarkers, and their combined use with other related circulating markers (cBMEC and EPC) in early detection and diagnosis of cerebrovascular diseases (CVD) or central nervous system (CNS) disorders. | 2018-08-23 |
20180238876 | Method For Assessing Cell Surface Receptors of Blood Cells - The present invention relates to a novel method for rapid assessment of one or more subclasses of blood cells of interest (BCol), as for example CD4+ cells and CD8+ cells, in a liquid whole blood sample or a sample derived therefrom; a method of determining the cell count for such cells; a method for determining the CD4/CD8 ratio; a method for determining the quantity of such receptors in a sample; as well as a vertical flow assay device for performing such assessment. | 2018-08-23 |
20180238877 | ISOLATION OF ANTIGEN SPECIFIC B-CELLS - The present invention provides methods compositions and methods of isolating B-cells that produce an antibody specific for an antigen of interest. | 2018-08-23 |
20180238878 | ASSAYS FOR DETECTING T CELL IMMUNE SUBSETS AND METHODS OF USE THEREOF - The present disclosure provides methods for measuring the number of CD4+ OX40+ Foxp3+ lymphocytes in a sample containing cancer cells and lymphocytes obtained from a subject by labeling lymphocytes that show CD4 expression in the sample, then labeling lymphocytes that show OX40 expression in the sample, then labeling lymphocytes that show Foxp3 expression in the sample, then measuring the number of CD4+ OX40+ Foxp3+ lymphocytes in the sample. Further provided are methods for determining the prognosis of a subject, predicting responsiveness of a subject having cancer to an OX40 agonist treatment, and methods for treating or delaying progression of cancer based on the number of CD4+ OX40+ Foxp3+ lymphocytes in a sample. | 2018-08-23 |
20180238879 | METHODS AND MATERIALS FOR ASSESSING IMMUNE SYSTEM PROFILES - This document provides methods and materials involved in assessing immune system profiles. For example, methods and materials for performing flow cytometry to determine the number of CD4 | 2018-08-23 |
20180238880 | CD127 EXPRESSION INVERSELY CORRELATES WITH FOXP3 AND SUPPRESSIVE FUNCTION OF CD4+ TREGS - The invention provides methods of isolating CD127 | 2018-08-23 |
20180238881 | RAPID IMMUNOCHROMATOGRAPHIC LATERAL FLOW ASSAY FOR EARLY ZIKA DISEASE DETECTION - The invention relates to a sensitive and specific rapid immunochromatographic lateral flow assay for Zika virus infection. The rapid assay of the invention can determine early, intermediate, and late Zika virus infection status. | 2018-08-23 |
20180238882 | KITS SUITABLE FOR USE IN ELECTROCHEMILUMINESCENCE METHODS AND METHODS OF EFFECTING A SPECIFIC-BINDING NON-WASH ASSAY - The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate. | 2018-08-23 |
20180238883 | FLUID ACTUATION OF INSTRUMENTS THROUGH A STERILE BARRIER - A robotic surgical system includes a fluid drive system and a surgical instrument removably positioned in operative engagement with the drive system. A sterile barrier covers non-sterile portions of the surgical system. Features of the sterile barrier are used to transfer motion output from the fluid drive system to the instrument for actuation of the instrument. | 2018-08-23 |
20180238884 | PD-L2 BIOMARKERS PREDICTIVE OF PD-1 PATHWAY INHIBITOR RESPONSES IN ESOPHAGOGASTRIC CANCERS - The present invention is based on the identification of novel biomarkers predictive of responsiveness of esophagogastric cancers to inhibitors of the PD-1 pathway. | 2018-08-23 |
20180238885 | NEW METHOD FOR TREATING AND PROGNOSING CANCER - The present invention relates to an in vitro method for determine the prognosis of the survival time of a patient suffering from a cancer comprising the steps consisting of i) determining the expression level of the couple DNMT3A/ISGF3γ in a sample from said patient, ii) comparing said expression level with a predetermined reference value and iii) providing a good prognosis when the expression level is lower than the predetermined reference value and a poor prognosis when the expression level is higher than the predetermined reference value. The invention also relates a compound which is a DNMT3A/ISGF3γ antagonist or a compound which is a DNMT3A/ISGF3γ gene expression inhibitor for use in the treatment and prevention of cancer. | 2018-08-23 |
20180238886 | METHODS FOR TREATING HEMATOLOGICAL CANCER AND THE USE OF BIOMARKERS AS A PREDICTOR FOR RESPONSIVENESS TO TREATMENT COMPOUNDS - A method for predicting the responsiveness of a patient having a hematological cancer to a treatment compound, comprising obtaining a biological sample from the patient having the hematological cancer; determining the expression level of one, two, three, four, five, or more genes; and comparing the expression level of the one, two, three, four, five, or more genes in the biological sample with a reference expression level of the same genes, wherein the treatment compound is 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione (lenalidomide), 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione (Compound A), or a stereoisomer, pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or a polymorph thereof. | 2018-08-23 |
20180238887 | PHARMACEUTICAL USE OF ACTININ-4 INVOLVED IN INDUCTION OF CERVICAL CANCER - The present invention relates to a pharmaceutical use of actinin-4 involved in the induction of cervical cancer and more specifically, characterizes actinin-4 as a marker protein capable of inducing cervical cancer, thereby providing the pharmaceutical use of actinin-4 that can be used in the diagnosis, prevention or treatment of cervical cancer. | 2018-08-23 |
20180238888 | NEW BIOMARKER FOR OUTCOME IN AML PATIENTS - The present invention relates to a method for predicting the survival time of a patient suffering from acute myeloid leukemia (AML) comprising i) determining in a sample obtained from the patient the expression level of NKp | 2018-08-23 |
20180238889 | THE SCANO-miR PLATFORM IDENTIFIES A DISTINCT CIRCULATING MICRORNA SIGNATURE FOR THE DIAGNOSIS OF DISEASE - The disclosure relates to the identification of a novel molecular signature based on the differential expression of circulating microRNAs (miRNA) in serum samples specific to patients with clinically significant diseases or disorders, such as cancer. | 2018-08-23 |
20180238890 | METHODS AND MATERIALS FOR DETECTION, DIAGNOSIS AND MANAGEMENT OF OVARIAN CANCER - The subject invention concerns methods using a panel of proteins to detect, diagnose, and monitor therapy during treatment of ovarian cancer in a female patient. The proteins were identified using proteomics analyses of plasma samples obtained preoperatively from ovarian cancer patients versus those of healthy control women. Such a panel has utility for the diagnosis of ovarian cancer, screening for ovarian cancer and possibly therapeutic monitoring. | 2018-08-23 |
20180238891 | Cancer Detection Method - The present disclosure relates to methods of determining whether a subject has cancer. More particularly, the present disclosure relates to a method of determining whether a subject has cancer when a pathological assessment of cell morphology is negative for the cancer. More particularly, the present disclosure relates to a method of determining whether a morphologically normal cell is malignant. Identification of malignant cells, when a pathological assessment of cell morphology is negative for cancer, is based upon detecting the binding of an anti-telomerase antibody to clinically relevant cells. | 2018-08-23 |
20180238892 | METHOD OF DIAGNOSING, TREATING AND DETERMINING PROGRESSION AND SURVIVAL OF CANCER CELLS USING BCL-2 ANTAGONIST OF CELL DEATH (BAD) PATHWAY GENE SIGNATURE - The present invention relates to the BAD pathway's influence on development, progression, chemo-sensitivity, and overall survival for multiple human cancers and its potential as a therapeutic target to increase chemo-sensitivity. BAD pathway expression was associated with the development and/or progression of breast, colon, and endometrial cancers, relapse-free survival from breast cancer, and overall survival from ovarian, colon, and brain cancers. Expression was also associated with in vitro sensitivity to a range of cytotoxic agents. pBAD levels were higher in cancer versus immortalized normal cells and chemo-resistant versus—sensitive cancer cells and associated with increased cell proliferation. | 2018-08-23 |
20180238893 | USE OF CIRCULATING CELL BIOMARKERS IN THE BLOOD FOR DETECTION AND DIAGNOSIS OF DISEASES AND METHODS OF ISOLATING THEM - A new sensitive cell biomarker of solid tumors and viral infection is identified in blood. This biomarker can be used to determine presence of carcinomas, sarcomas, and viruses, rapid determination of treatment response, early detection of cancer, early detection of cancer recurrence, and may be used to determine therapy. | 2018-08-23 |
20180238894 | METHODS OF DETECTING DISEASES OR CONDITIONS USING CIRCULATING DISEASED CELLS - This invention provides methods of using circulating diseased cells in the diagnosis, prognosis, or monitoring of diseases or conditions. The invention also provides methods of using circulating diseased cells to identify markers of diseases or conditions. | 2018-08-23 |
20180238895 | ANTIBODIES RECOGNIZING A CARBOHYDRATE CONTAINING EPITOPE ON CD-43 AND CEA EXPRESSED ON CANCER CELLS AND METHODS USING SAME - The present invention provides novel antibodies specifically bind to an epitope on CD43 and CEA expressed on nonhematopoietic cancer cells, but do not specifically bind to a CD43 expressed by a leukocyte or by a Jurkat cell, and is capable of inducing apoptosis of the nonhematopoietic cancer cell after binding to the epitope on cell surface of the nonhematopoietic cancer cell in the absence of cytotoxin conjugation and immune effector function, wherein the epitope comprises a carbohydrate structure and the binding of the antibody to the epitope is inhibited by a carbohydrate comprising a Le | 2018-08-23 |
20180238896 | FREE NGAL AS A BIOMARKER FOR CANCER - Uncomplexed neutrophil gelatinase associated lipocalin (NGAL) is present at increased levels in individuals with atypical ductal hyperplasia (ADH), a major risk factor for future breast cancer development; in individuals that have ovarian cancer; and in individuals that have breast cancer, both invasive and noninvasive. Accordingly, the present invention is directed to measuring uncomplexed NGAL levels in urine as a primary screen to determine if an individual is either at risk of developing, or has developed cancer, e.g., cancer of epithelial origin including breast and ovarian cancer. | 2018-08-23 |
20180238897 | SELECTIVE NEAR-INFRARED OPTICAL IMAGING OF NECROTIC CELLS AND SIMULTANEOUS CELL FIXING AND COUNTER STAINING WITH METALLACROWN COMPLEXES - In an example of a method for simultaneously fixing and staining cells, the cells are initially incubated in a solution including a Ln(III)Zn | 2018-08-23 |
20180238898 | MEANS AND METHODS FOR MONITORING INFLAMMATION - The application discloses methods, kits and a novel biomarker to detect and/or to prognose inflammation in patients. The diagnostic test is based on measuring the ratio of galactosylated and non-galactosylated specific N-glycans as obtained by enzymatic treatment of the total mixture of proteins present in a body fluid such as blood, serum or plasma. | 2018-08-23 |
20180238899 | NOVEL GLUCOSE DERIVATIVE, AND CELL IMAGING METHOD AND IMAGING AGENT USING SAID DERIVATIVE - Provided is a glucose derivative, which is taken into cells via a membrane sugar transport system and is represented by formula (1). Also provided are an imaging agent and an imaging method for a cell or intracellular molecule using said glucose derivative. Further provided is a method for detecting cancer cells with good accuracy using said glucose derivative and an imaging agent to be used in said method. More specifically provided are D-glucose derivatives and L-glucose derivatives in which glucose is bound to the 7-position of a fluorescent molecular group with a coumarin backbone or a quinolone backbone. Also provided are a cell imaging agent and imaging method using the derivative. A cancer cell imaging agent and imaging method using the L-glucose derivative is also provided. G is a group selected from formulas (G1)-(G4) below. | 2018-08-23 |
20180238900 | METHOD AND KIT FOR DETECTING GLUTATHIONE - A method for detecting glutathione includes mixing a sample including glutathione, 9-bromomethyl acridine (Br-MA) and a derivatization solvent to form a reaction solution. A derivative reaction occurs between Br-MA and glutathione to obtain a derivatization solution including a glutathione derivative with a thiol group being substituted with a tag. Excess Br-MA is removed by adding an interference removing solvent into the derivatization solution, followed by vortexing and centrifugation to obtain an aqueous layer solution. The aqueous layer solution is used as an analytic solution, and the glutathione derivative in the analytic solution is detected to obtain a glutathione value. The present invention also provides a kit for detecting glutathione which is adapted to carry out the method for detecting glutathione. | 2018-08-23 |
20180238901 | HIGH PRECISION SPECTRAL FRET ASSAYS - Provided herein are methods for identifying a compound that alters fluorescence resonance energy transfer (FRET) of a protein. In one embodiment, the method includes providing a target protein, where the target protein includes two heterologous domains, each domain having chromophores that together act as a FRET pair. In another embodiment, the method includes providing a target protein and a second protein, wherein the target protein includes a first heterologous domain including a chromophore, and the second protein includes a second heterologous domain including a chromophore, where the chromophores together act as a FRET pair. The method further includes contacting a sample including the target protein and optional second protein with a test compound to form a mixture, and measuring a fluorescence emission spectrum of the mixture during exposure to a light source. The fluorescence emission spectrum is decomposed into at least two component spectra, where in one embodiment the component spectra include a donor chromophore emission and an acceptor chromophore emission. A ratio (R) is then calculated, and in one embodiment, R is determined according to | 2018-08-23 |
20180238902 | METHODS FOR USING ANTIBODIES AND ANALOGS THEREOF - Camelid and shark single-domain heavy chain antibodies lacking the light chains, and their analogs are disclosed. Methods for using the antibodies and their analogs to detect antigens are disclosed. Methods to derivatize such antibodies and analogs to develop diagnostic assays are described. Also provided are kits, and methods of using such diagnostics assays. | 2018-08-23 |
20180238903 | Immunoassay for Collagen Type VIII Sequences - The invention provides an immunological binding partner specifically reactive with a C-terminal epitope of the α1 chain of collagen Type VIII or with an N-terminal epitope of the mature form of the α1 chain of collagen Type VIII, and a method of immunoassay for detecting or quantitating in a sample the C-terminal epitope or the N-terminal epitope of the mature α1 chain of collagen type VIII. | 2018-08-23 |
20180238904 | IMMUNE CHECKPOINT MOLECULAR FITNESS PROFILING BY MASS SPECTROMETRY - The present disclosure relates generally to the analysis of immune checkpoint proteins involved in cancer. In particular, the present disclosure provides material and methods for determining abundance ratios of various immune checkpoint proteins (e.g., PD-1, PD-L1, and PD-L2) present in a biospecimen sample based on quantification of peak area using mass spectrometry analysis. The methods disclosed herein provide an alternative platform for diagnosing and treating cancer, especially in cases limited by ineffective antibody recognition. | 2018-08-23 |
20180238905 | METHODS AND COMPOSITIONS FOR DIAGNOSIS OF ECTOPIC PREGNANCY - Methods and compositions are provided for diagnosing ectopic pregnancy in a mammalian subject by detecting changes in expression of ISM2, ADAM12, PST1, PSG7, PST11, PSG9, PSG2 and other genes identified therein, including combinations thereof. A selected gene, gene transcript or protein/peptide expression product, or profiles or signatures formed by combinations of same, detected in a biological fluid of a subject, enables comparison of the corresponding genes, proteins or profiles from that of a reference or control having a normal intrauterine pregnancy. Detection of characteristic changes in the gene profile or protein expression signature of the subject is correlated with a diagnosis of ectopic pregnancy. Various compositions for use in such diagnosis include PCR primer-probe sets or ligands, labeled or immobilized, which are capable of detecting the changes in expression or translation of these targets. | 2018-08-23 |
20180238906 | METHOD FOR EVALUATING THE POSSIBILITY OF SUFFERING FROM PANCREATIC DISEASE - The purpose of the present invention is to provide a method for evaluating the possibility of suffering from pancreatic disease on the basis of the concentration of a pancreatic disease marker in a duodenal juice sample. The method for evaluating the possibility of suffering from pancreatic disease of the present invention has a step for (a) measuring the concentration of the pancreatic disease marker in a duodenal juice sample taken from a subject and a step for (b) evaluating the possibility of the subject suffering from pancreatic disease on the basis of the concentration of the pancreatic disease marker measured in step (a) and the age of the subject. | 2018-08-23 |
20180238907 | MARKERS AND THEIR USE IN BRAIN INJURY - The invention relates to a combination of biomarkers and their use in brain injury or mild traumatic brain injury (mTBI) detection. | 2018-08-23 |
20180238908 | NEURODEGENERATIVE DISORDERS - An amyloidogenic peptide biospecific agent comprises a nanoparticle which is visible under near infrared (NIR) and/or using Magnetic Resonance Imaging (MRI) and/or Computed Tomography (CT). The biospecific agent further comprises at least one antibody or antigen binding fragment thereof, which is immunospecific for a transferrin receptor and an amyloidogenic peptide. | 2018-08-23 |
20180238909 | MULTIPLEX BIOMARKER FOR USE IN EVALUATION OF STATE OF ACCUMULATION OF AMYLOID B IN BRAIN, AND ANALYSIS METHOD FOR SAID EVALUATION - Provided are a biomarker for evaluating a cerebral Aβ accumulation state using amyloid precursor protein (APP)-derived Aβ and Aβ-like peptides in a living body-derived sample as an index, and a method for analysis thereof. A marker for determining a cerebral Aβ accumulation state, the marker comprising a combination of at least two ratios selected from the group consisting of: a ratio of Aβ1-39 (SEQ ID NO.: 1) level to Aβ1-42 (SEQ ID NO.: 3) level: Aβ1-39/Aβ1-42; a ratio of Aβ1-40 (SEQ ID NO.: 2) level to Aβ1-42 (SEQ ID NO.: 3) level: Aβ1-40/Aβ1-42; and a ratio of APP669-711 (SEQ ID NO.: 4) level to Aβ1-42 (SEQ ID NO.: 3) level: APP669-711/Aβ1-42, in a living body-derived sample. | 2018-08-23 |
20180238910 | METHODS FOR PROVIDING INFORMATION RELEVANT TO DIAGNOSIS OF NEURODEGENERATIVE DISORDER - A method for providing information relevant to the diagnosis of a neurodegenerative disorder. The method includes (i) obtaining a biological sample containing vesicles from a subject, (ii) measuring the level of amyloid beta in the biological sample using an antibody specific for the N-terminus of amyloid beta, and (iii) comparing the measured level of amyloid beta in the biological sample with the level of amyloid beta in a previously prepared control sample. | 2018-08-23 |
20180238911 | BIOCHEMICAL MARKERS OF RED BLOOD CELL STORAGE AND TOXICITY - Compositions and methods for determining post-transfusion survival or toxicity of red blood cells and the suitability of red blood cell units for transfusion by measuring the levels of one or more markers in a red blood cell sample are provided. | 2018-08-23 |
20180238912 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE - A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula I: | 2018-08-23 |
20180238913 | Apparatus and Method to Determine Stroke Subtype - Apparatus and methods are provided to determine stroke subtype by hemostasis measurement at point of care or first response. A testing apparatus and methods may provide first test to determine an ischemic or hemorrhagic indication and a second test to provide a therapeutic influence before classifying a stroke substype. | 2018-08-23 |
20180238914 | MEANS AND METHODS FOR DIAGNOSING CARDIAC DISEASE IN A SUBJECT - The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing a cardiac disease in a subject based on determining the amounts of at least three lipid metabolite biomarkers and at least one further cardiac biomarker. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices. | 2018-08-23 |
20180238915 | Microfluidic Platform For Rapid Biologics Analysis - The invention relates to generally applicable methods and platforms for the assessment of a wide variety of drugs, including biologic drugs. Aspects of the invention further relate to such methods and platforms capable of measuring not only the equilibria but also the kinetics of drug-receptor interactions. Such methods and platforms can be based on mobility-based assays, wherein species are separated along at least one separation dimension. By modulating the mobility, e.g., electrophoretic mobility, of at least one of a drug and a receptor, the separation of drug, receptor, and drug-receptor complex can be optimized, e.g., by enhancing spatial separation of one or more of the foregoing species from the others. | 2018-08-23 |
20180238916 | METHOD AND APPARATUS FOR DETECTING ACUTE USE OF TARGET SUBSTANCE(S) - Methods and devices for sampling, processing and identifying acute use of a substance or substances of abuse are provided. Systems and kits for sampling, processing and identifying acute use of a substance of abuse is also provided. | 2018-08-23 |
20180238917 | ANALYTE EXTRACTION APPARATUS AND METHOD - Disclosed is a method and apparatus for determining a concentration of a glycopeptide antibiotic containing a phenol moiety such as Vancomycin in a complex sample matrix by extracting the glycopeptide antibiotic from a metered portion of the complex sample matrix by exposing said metered portion to an extraction material having an affinity with the glycopeptide antibiotic; and exposing the extraction material to a metered portion of an eluent for releasing the glycopeptide antibiotic from the extraction material; and by determining a concentration of the glycopeptide antibiotic by adding a Gibbs reagent ( | 2018-08-23 |
20180238918 | DIAGNOSTIC TEST READER SYSTEM - A diagnostic test reader system including two or more reader modules and at least one mother module is provided. Each of the reader modules includes a unique code and is configured for reading a specific test cartridge type. Each of the reader modules is configured to be in data communication with the mother module for receiving instructions from the mother module and for transmitting read and/or derived data to the mother module. The mother module is configured for communicating individually with each of the reader modules. | 2018-08-23 |
20180238919 | IN-VITRO DIAGNOSTIC ANALYSIS METHOD AND SYSTEM - A method and system for automatic in-vitro diagnostic analysis are described. The method includes adding a first reagent type and a second reagent type to a first test liquid during a first and second cycle times respectively. The addition of the first reagent type to the first test liquid includes parallel addition of a second reagent type to a second test liquid during the first cycle time. The addition of the second reagent type to the first test liquid includes parallel addition of a first reagent type to a third test liquid during the second cycle time, respectively. | 2018-08-23 |
20180238920 | STORAGE APPARATUS STORING SPECIMEN CONTAINER AND EXAMINATION SYSTEM USING THE SAME - There is provided a storage apparatus including a storage case which stores a specimen container accommodating a specimen inside and having a wireless tag recorded with identification information on a side surface, and an antenna surrounding the periphery of the specimen container stored in the storage case. | 2018-08-23 |
20180238921 | DISPOSABLE ANALYTICAL MICROPROCESSOR DEVICE - The present invention generally relates to the determination of an analyte concentration (quantitative determination) or whether an analyte threshold level has been passed (qualitative determination) in a biological sample through employment of a disposable analytical microprocessor device. The device can include a batch-specific, self-executable algorithm for the calculation of the analyte concentration. | 2018-08-23 |
20180238922 | METHODS AND APPARATUS PROVIDING REDUCED CARRYOVER DURING PIPETTING OPERATIONS - Methods and apparatus configured and adapted to provide less carryover in an automated clinical analyzer are disclosed. The methods include aspirating a scavenger segment (e.g., a buffer- and surfactant-containing segment) into the interior of a pipette along with the specimen or reagent. The scavenger film aids in preventing adherence of the specimen or reagent to the interior of the pipette. Apparatus configured to carry out the methods are provided, as are other aspects. | 2018-08-23 |
20180238923 | DISPENSING SYSTEM, AND DISPENSING METHOD - A dispensing system comprising a robot configured to move a dispenser for suctioning a liquid to be dispensed, a camera for capturing an image including at least a tip of the dispenser, a liquid surface of the liquid, and an object not to be dispensed located below the liquid surface, and circuitry configured to acquire, based at least in part on the image captured by the camera, surface location information for the liquid surface, boundary location information for a boundary between the liquid and the object not to be dispensed, and dispenser location information for the tip of the dispenser on the basis of the image, and control the robot to lower the dispenser based at least in part on the dispenser location information, the surface location information, and the boundary location information. | 2018-08-23 |
20180238924 | PUMP ASSEMBLY HAVING A CONTROLLER INCLUDING A CIRCUIT BOARD AND 3D ROTARY SENSOR FOR DETECTING ROTATION OF ITS PUMP - A pump assembly and a method for sensing rotary motion of the pump therein are disclosed. The pump assembly includes a pump, a controller, and an optional driven electric motor. The components may be axially aligned and mounted relative to one another. The controller includes a circuit board that is oriented in an axial direction of the pump assembly so that it faces in a radial direction. A 3D rotary sensor is mounted on the circuit board and is designed to detect motion parallel to its front face and motion in a plane perpendicular to its front face, including rotary motion of the pump, for output to the controller. The controller is configured to control the pump via controlling the drive shaft of the motor or pump. | 2018-08-23 |
20180238925 | ACCELEROMETER TECHNIQUES TO COMPENSATE PACKAGE STRESS - Techniques for compensating package stress of a proof mass are provided. In an example, a proof mass can be suspended from a substrate by a proof mass anchor. The first proof mass can have a major surface that defines a first plane. Portions of electrodes forming part of the proof mass can be symmetric with each other across a first line, wherein the first line bisects the first proof mass anchor, extends parallel to the first plane and extends between the first electrode and the second electrode. | 2018-08-23 |
20180238926 | INERTIA SENSOR AND METHOD OF MANUFACTURING THE SAME - Airtightness in a cavity of an inertial sensor (acceleration sensor) is increased to achieve high sensitivity. In the acceleration sensor having movable electrodes VE | 2018-08-23 |
20180238927 | ELECTRODE LAYER PARTITIONING - A MEMS sensor includes a proof mass that is suspended over a substrate. A sense electrode is located on a top surface of the substrate parallel to the proof mass, and forms a capacitor with the proof mass. The sense electrodes have a plurality of slots that provide improved performance for the MEMS sensor. A measured value sensed by the MEMS sensor is determined based on the movement of the proof mass relative to the slotted sense electrode. | 2018-08-23 |
20180238928 | METHOD OF MANUFACTURING PHYSICAL QUANTITY SENSOR DEVICE AND PHYSICAL QUANTITY SENSOR DEVICE - An inner housing part has through-holes for connecting first lead pins (power supply terminal, output terminal, ground terminal) with the connector pins. The inner housing part has grooves that house second lead pins for adjusting output signals of a sensor chip. Three of the grooves each has a shape in which a distance between opposing sides of the groove is less than a diameter of the second lead pin that corresponds to the groove. The inner housing part is fixed to a case by a thermoset adhesive so as to house lead pins arranged in the case included in a sensor element. The second lead pins are fitted in the grooves, suppressing lifting of the inner housing part during curing of the adhesive. | 2018-08-23 |
20180238929 | Acceleration Sensor - A membrane (mass body) included in an acceleration sensor includes a moving portion, a moving portion electrically separated from the moving portion, and a mechanical junction portion that mechanically connects the moving portion and the moving portion in a y-axis direction. The mechanical junction portion includes a first portion extending in a direction having a first angle with respect to the y-axis direction and a second portion extending in a direction having a second angle different from the first angle with respect to the y-axis direction in an xy plane, and is formed to have a non-linear shape in an x-axis direction. | 2018-08-23 |
20180238930 | MEMS-BASED SENSOR SUITE - A microelectromechanical (MEMS) sensor suite including a three axis accelerometer including an accelerometer sensor polyhedron having a series of faces, and a series of axial accelerometers on three faces of the series of faces of the accelerometer sensor polyhedron. The MEMS sensor suite also includes a three axis magnetometer including a magnetometer sensor polyhedron having a series of faces, and a series of axial magnetometers on three faces of the series of faces of the magnetometer sensor polyhedron. | 2018-08-23 |
20180238931 | DEVICE AND METHOD FOR MEASURING AND/OR MODIFYING SURFACE FEATURES ON A SURFACE OF A SAMPLE - The present document describes a device for measuring and/or modifying surface features and/or sub-surface features on or below a surface of a sample. The system comprises a sample carrier, one or more heads, and a support structure. The support structure comprises a reference surface for providing a positioning reference. The heads are separate from the sample carrier and the support structure, and the device further comprises a pick and place manipulator arranged for positioning the heads at respective working positions. The manipulator comprises a gripper and an actuator for moving the gripper, wherein the actuator is arranged for providing a motion in a direction transverse to the reference surface. The gripper is arranged for engaging and releasing the respective heads from the transverse motion. The document also describes a method of measuring and/or modifying surface features on a surface of a sample. | 2018-08-23 |
20180238932 | CONDUCTIVE PROBE FOR INSPECTION AND SEMICONDUCTOR INSPECTION DEVICE - Provided is a conductive probe having a first end portion and a second end portion opposing the first end portion. The first end portion includes first to fourth linear ridges and first to fifth vertexes, and the first to fourth linear ridges are spaced from one another and arranged to form a cross. The first to fourth vertexes are located on an outer circumference of the first end portion and further arranged between the first linear ridge and the second linear ridge, between the second linear ridge and the third linear ridge, between the third linear ridge and the fourth linear ridge, and between the fourth linear ridge and the first linear ridge, respectively. | 2018-08-23 |
20180238933 | DETERMINING ENERGY USAGE OF A RESIDENCE BASED ON CURRENT MONITORING - Systems and methods include determining energy usage of a residence from a current that flows through a first main conductor and a second main conductor that transport the current into the residence. Embodiments of the present disclosure relate to sensors ( | 2018-08-23 |
20180238934 | FIBER-OPTIC CURRENT SENSOR WITH TOLERANCE TO CONNECTOR MISALIGNMENT - A fiber-optic current sensor includes an opto-electronics module, a sensor head and a connecting fiber connecting the opto-electronics module to the sensor head. The sensor includes a first and a second beam splitter, between which the measuring light runs in two branches. One fiber connector is arranged in each branch, for connecting a cable assembly to the opto-electronics module. The optical path lengths between the two connectors and the second beam splitter are different, such that light waves cross-coupled into an orthogonal polarization mode due to angular misalignment of the connectors become incoherent with the non-cross-coupled waves returning from the sensor head. | 2018-08-23 |
20180238935 | ABNORMALITY DIAGNOSIS APPARATUS - An abnormality diagnosis apparatus performs: a first step of diagnosing a shortage of precharge voltage or a short-circuit failure between electrodes of a capacitor based on a detection value of a precharge voltage detection circuit in a state where a first relay and a second relay are turned off, and a precharge circuit is operated;, a second step of diagnosing, after a normal determination in the first step, a disconnection failure of a precharge path based on the detection value of the precharge voltage detection circuit or a detection value of an inter-relay voltage detection circuit in a state where the first relay and the second relay are turned off, and the precharge circuit is not operated; and a relay failure diagnosis step of diagnosing, after a normal determination in the second step, a short-circuit failure and an open failure of the first relay or the second relay. | 2018-08-23 |
20180238936 | POWER INDUCTOR, BOARD HAVING THE SAME, AND CURRENT MEASUREMENT METHOD USING THE SAME - A power inductor includes: a body including a magnetic material; an internal coil disposed in the body and including a plurality of coil patterns; and a sensing coil disposed on the body and facing the internal coil. | 2018-08-23 |
20180238937 | APPARATUS FOR DETECTING ALTERNATING CURRENT ZERO CROSS AND VOLTAGE - A detection apparatus has an alternating-current voltage input unit and a generation circuit. The generation circuit generates a superimposition signal in which information indicating a timing of a zero cross in an alternating-current voltage inputted into the input unit and information indicating a voltage level of the alternating-current voltage are superimposed. | 2018-08-23 |
20180238938 | Current Sensor System - Systems and methods are described herein for reducing the effects of magnetic field cross-coupling in a multi-conductor current sensor system. A current sensor system includes one or more current sensors, each positioned proximate to at least one conductor and spaced from at least one other conductor. Each conductor carries a current intended to be measured by a respective current sensor. The current sensors include one or more magnetic field sensing elements to generate a magnetic field signal indicative of a detected magnetic field. A characterization measurement is performed to determine the coupling between each current sensor and the respective current conductor and to determine the coupling between the current sensor and the other ones of the current conductors, by providing a reference current to each of the conductors and measuring the outputs at each of the current sensors. The characterization measurement can be used to generate a coupling matrix. | 2018-08-23 |
20180238939 | EXPECTED SENSOR MEASUREMENT RECEIPT INTERVAL ESTIMATION - A current measurement receipt interval is computed as a difference between a current receipt time of a current measurement from a sensor and a previous receipt time of a previous measurement from the sensor. An expected measurement receipt interval is estimated, based on a lowest mode of measurement receipt intervals including the computed current measurement receipt interval. | 2018-08-23 |
20180238940 | CURRENT DETECTION CIRCUIT - Provided is a current detection circuit that can detect current in a wide dynamic range, with high precision, and with good step response. Voltage that is generated between both ends of a resistor connected between a high-voltage power supply and a load is amplified by amplifiers and compared, by comparators, to the voltage of a saw-tooth wave signal; the lengths of signals indicating the comparison results from the comparators during an inclined period in which the voltage of the saw-tooth wave signal linearly and gradually increases or decreases and the length of the inclined period are detected; and the current flowing to the resistor is detected on the basis of the ratio between the detected lengths. | 2018-08-23 |
20180238941 | POWER DETECTOR - Disclosed is a power detector. The power detector in which calibration is performed to minimize errors caused by a process variation and a temperature variation in a structure that allows a wide input dynamic range of the power detector at a low supply voltage is provided. | 2018-08-23 |
20180238942 | INTELLIGENT ELECTRONIC DEVICE AND METHOD THEREOF - An intelligent electronic device (IED) having a gain control unit adapted to selectively regulate operating ranges of output signals of a sensing circuit of the device is described. In one embodiment, the IED is a digital electric power and energy meter, which operating ranges for supply voltages and supply currents of electrical services may be adjusted to match pre-determined ranges for input signals of a data acquisition system or a data processing module of the meter. | 2018-08-23 |
20180238943 | METHODS FOR EXTENDING FREQUENCY TRANSFORMS TO RESOLVE FEATURES IN THE SPATIO-TEMPORAL DOMAIN - A signal processing method generates a time-frequency domain representation of an input signal for the purpose of signal detection, signal display, and application of filtering operations, such as sample accurate spectral editing. The method may include receiving an input signal in the time domain in a processor. The input signal may include a plurality of transform frames. The input signal is transformed into the frequency domain using a frequency transform. Time-frequency matrices are generated from the frequency transform. Crossfrequency phase coupling is applied between adjacent frequency bins to introduce synchronization between adjacent frequencies and to generate smoothed time-frequency matrices with sample-accurate frequency magnitudes. The frequency information can be edited in the time-frequency domain specific to a single sample of the transform frame to alter unwanted signal features. A modified time domain representation of the edited input signal can be generated from the modified time-frequency matrices. | 2018-08-23 |
20180238944 | CAPACITANCE DETECTION METHOD AND CAPACITANCE DETECTION APPARATUS USING THE SAME - Disclosed is a capacitance detection apparatus including a panel, having a parasitic capacitor formed therein, and an electrode that forms, in operation of the apparatus a self-capacitor with an object; a compensation capacitor configured to share charges with the parasitic capacitor and the self-capacitor to output a detection signal with compensation for an influence of the parasitic capacitor; a switch unit including a plurality of switches which get turned on or off so that the compensation capacitor compensates for the influence of the parasitic capacitor, and an output voltage adjusting unit connected to the compensation capacitor and configured to adjust an output range of the detection signal output by the compensation capacitor. | 2018-08-23 |
20180238945 | Method and Device for Determining a Sensor Coil Inductance - A method for determining a sensor coil inductance of an eddy current sensor using an LC oscillator circuit includes determining the sensor coil inductance via integration, as a function of an oscillation frequency and a resonance capacitance of the LC oscillator circuit. The method further includes detuning, at least once, the oscillation frequency during the integration. | 2018-08-23 |
20180238946 | DEVICE AND METHOD OF TESTING DUAL-FREQUENCY NONLINEAR VECTOR NETWORK PARAMETERS - A device and method of testing the dual-frequency nonlinear vector network parameters. In view of the challenge of the nonlinear behavioral model characterization of the microwave device components, and the current situation of the nonlinear vector network parameter testing, the disclosed device and method of testing the dual-frequency nonlinear vector network parameters redefines the nonlinear model parameters of the nonlinear device components, gives the definition of the test parameter (W-parameter), solves the challenges of the dual-frequency nonlinear behavioral model characterization and testing for the microwave device components, and makes it more convenient to measure the nonlinear characteristics of the mixer, amplifier and passive device components. | 2018-08-23 |