34th week of 2022 patent applcation highlights part 40 |
Patent application number | Title | Published |
20220268695 | DEVICE FOR THE TEMPERATURE-COMPENSATED OPTICAL DETECTION OF AN OXYGEN CONTENT OF A FLUID - A sensor arrangement includes a reaction subassembly having a housing and a detector subassembly. The housing is a layered component arrangement encompassing a luminophore-containing reaction laminate excitable, by irradiation with a first electromagnetic radiation of a first wavelength, to emit a second electromagnetic radiation of a second wavelength different from the first wavelength; and a temperature-detection laminate emitting an infrared radiation. The housing includes an opening for introducing a fluid, a reaction window and a temperature-sensing window. The reaction window transmits the first and second electromagnetic radiation, and the temperature-sensing window is penetrable by infrared radiation. The detector subassembly encompasses a radiation source emitting the first electromagnetic radiation, a radiation detector detecting the second electromagnetic radiation, and an infrared detector detecting, through the temperature detection window, the infrared radiation emitted from the temperature detection laminate. The reaction laminate and the temperature-detection laminate are embodied separately. | 2022-08-25 |
20220268696 | SENSORY EVALUATION METHOD FOR SPECTRAL DATA OF MAINSTREAM SMOKE - A sensory evaluation method for spectral data of mainstream smoke includes: performing a data enhancement on spectral data of mainstream smoke of a plurality of cigarettes; extracting a shallow spectral characteristic from the spectral data of the mainstream smoke of each cigarette; obtaining a shallow sensory quality result of the spectral data of the mainstream smoke of each cigarette based on the spectral data of the mainstream smoke of each cigarette and the shallow spectral characteristic; extracting deep spatial characteristics from the spectral data of the mainstream smoke of each cigarette; obtaining a deep sensory quality result based on the spectral data of the mainstream smoke of each cigarette and the deep spatial characteristics; obtaining a comprehensive sensory quality result according to the shallow sensory quality result and the deep sensory quality result. The sensory evaluation method achieves accurate screening of unknowns in the mainstream smoke. | 2022-08-25 |
20220268697 | ELECTRO-OPTICAL SEMI-TRANSPARENT PHOTONIC UP-CONVERTER - A night vision optical device includes an underlying device configured to be sensitive to light in a first spectrum, and to provide output light based on absorbing light in the first spectrum. The night vision optical device further includes a stacked device overlapping the underlying device. The stacked device includes one or more openings formed in the underlying device to form one or more transparent regions which are transparent to the light in the first spectrum to allow light in the first spectrum to pass through to the underlying device. The stacked device is sensitive to light in a second spectrum. The stacked device outputs light in the first spectrum to the underlying device as a result of absorbing light in the second spectrum. Thus, the underlying device outputs light based both on light passing through the transparent regions and on light output by the stacked device. | 2022-08-25 |
20220268698 | MULTI-PASS SPECTROSCOPY APPARATUS, ASSOCIATED SAMPLE HOLDER AND METHODS - A sample cell includes an annular support surrounding a sample region. A set of reflectors of the annular support define an optical path that reflects a source beam in a sequence of alternating directions through the sample region at a plurality of different angles such that the source beam exits the set of reflectors after having passed through the sample region a plurality of times. A micro-cell is positionable in the sample region including multi-dimensionally distributed nano-pores. A slidingly adjustable lens forms part of source and detector photomixing packages. | 2022-08-25 |
20220268699 | CAVITY-ENHANCED FOURIER TRANSFORM SPECTROSCOPY FOR CHIRAL ANALYSIS - A chiral molecule can be defined as a molecule that has a non-superimposable mirror image. These mirror images can be referred to as enantiomers. The enantiomers generally have the same set of bond lengths and bond angles in their three-dimensional geometry. Apparatus and techniques described herein can be used to perform analysis of chiral molecules using cavity-enhanced molecular rotational spectroscopy. A sample cell can define a resonant cavity, and a sample introduction port can provide pulse-jet injection of an analyte molecule and a chiral tag to allow analysis of a complex comprising the analyte and chiral tag. | 2022-08-25 |
20220268700 | DETECTING APPARATUS - A detecting apparatus for use in specifying regions having different impurity concentrations in an ingot includes an ingot holding unit having a holding surface for holding the ingot thereon, an excitation light source for applying excitation light having a predetermined wavelength to a face side of the ingot held on the holding surface, and a photodetector for detecting fluorescence emitted from the ingot upon exposure to the excitation light and generating an electric signal representing a number of photons of only light whose wavelength is in an infrared radiation range, of the detected fluorescence. | 2022-08-25 |
20220268701 | METHODS FOR MICROSCOPY WITH ULTRAVIOLET SURFACE EXCITATION (MUSE) IMAGING - Described herein are methods for imaging a fluorescent bioassay (including a substrate, such as dispersed cellular sample, exposed to one or more exogenous fluorophore and/or fluorescent probe that accumulate in a structure of interest). The bioassay can be excited with Type-C ultraviolet (UVC) light produced by one or more light emitting diode (LED). The UVC can have a center wavelength that causes emission by the fluorescent bioassay. A digital optical device can collect a signal emitted from the fluorescent bioassay in response to the excitation. The methods relate in particular to Microscopy with Ultraviolet Surface Excitation (MUSE) imaging. | 2022-08-25 |
20220268702 | SYSTEMS AND METHODS FOR OPTOGENETIC ACTIVATION AND MONITORING - Optogenetic systems and methods for probing a specimen using spatio-temporally modulated illumination light are disclosed. A method may include generating illumination light, the illumination light including a plurality of illumination protocols temporally sampled and interleaved with one another at a time-division-multiplexed (TDM) sampling rate, each illumination protocol being for illuminating a respective region of interest (ROI) of a plurality of ROIs of the specimen. The illumination light may include either activation or excitation light, or both. The method may also include applying a spatio-temporal modulation to the illumination light and directing the resulting modulated illumination light onto the specimen. The modulation may include repeatedly imparting, at a pattern switching rate matched and synchronized with the TDM sampling rate, a sequence of a plurality of spatial modulation patterns to the plurality of temporally sampled and interleaved illumination protocols, each spatial modulation pattern mapping to a respective one of the ROIs. | 2022-08-25 |
20220268703 | OPTICAL DETECTION SYSTEM, BLOOD CELL ANALYZER, AND PLATELET DETECTION METHOD - An optical detection system, a blood cell analyzer and a platelet detection method are provided. The optical detection system includes: an optical subsystem, a flow chamber and a first detector; the optical subsystem includes a laser, a front optical assembly including an optical isolator, and a rear optical assembly including a blocking diaphragm. The laser is configured to emit a laser beam; the front optical assembly is configured to perform front optical treatment; the rear optical assembly is disposed downstream of the flow chamber in the propagation direction of the laser beam, and is configured to perform rear optical treatment on the scattered light and the laser beam converged at the blocking diaphragm; and the optical isolator is configured to isolate reflected light that is generated when the laser beam passes through the flow chamber. | 2022-08-25 |
20220268704 | Sub-wavelength Raman imaging with combined optical and electron excitation - Improved stimulated Raman spectroscopy is provided by replacing the Stokes (or anti-Stokes) optical source with a localized electromagnetic emitter that is excited with a non-electromagnetic excitation. Such a localized emitter can be an efficient Stokes (or anti-Stokes) source for stimulated Raman spectroscopy, and can also provide deep sub-wavelength spatial resolution. In a preferred embodiment, an electron beam from an electron microscope is used to excite the localized emitter. This provides combined Raman imaging and electron microscopy that has the two imaging modalities inherently registered with each other. | 2022-08-25 |
20220268705 | METHOD FOR MANUFACTURING SURFACE ENHANCED RAMAN SPECTROSCOPY TAGS - The present invention relates to the field of methods of manufacturing of surface enhanced Raman spectroscopy (SERS) tags. The manufacturing method according to the present invention is reproducible and versatile and enables the production in an expedient manner of high quantities of SERS tags characterized by a narrow size distribution and a high ratio of low-number aggregates. SERS tags manufactured by the inventive manufacturing method described herein provide increased ensemble SERS responses. | 2022-08-25 |
20220268706 | IMMUNOSENSOR - The present invention relates to methods for detecting analytes in a sample. The methods may also be used to determine the amount of analyte in the sample. The present invention also relates to antibody or antibody-like molecules and labelled antigens for use in these methods. | 2022-08-25 |
20220268707 | Phosphorous-Based Sensors For Detection Of Multiple Solvents - Embodiments of the present disclosure pertain to methods of monitoring an environment for the presence of a solvent by: (i) exposing the environment to a luminescent compound, where the relative luminescence emission intensity of the luminescent compound changes upon interaction with the solvent; and (ii) monitoring a change in the relative luminescence emission intensity of the luminescent compound, where the absence of the change indicates the absence of the solvent from the environment, and where the presence of the change indicates the presence of the solvent in the environment. The luminescent compounds include a phosphorous atom with one or more carboxyl groups, where the carboxyl groups are coordinated with one or more metallic ions (e.g., lanthanide ions and yttrium ions). The present disclosure also pertains to sensors for monitoring an environment for the presence of a solvent, where the sensors include one or more of the aforementioned luminescent compounds. | 2022-08-25 |
20220268708 | OPTICAL DETECTION DEVICE AND DETECTION METHOD THEREOF - An optical detection device and a detection method thereof are provided. A linear light source provides a light curtain formed by multiple light beams, the light curtain is located on a transportation path of transporting an object to be detected. A sensor set senses the part of light beams not interrupted by the object to be detected, so as to generate a sensing signal with various strengths. A control circuit determines a physical characteristic, moving speed and position of the object to be detected according to the strength of the sensing signal. | 2022-08-25 |
20220268709 | INSPECTION DEVICE AND METHOD OF MEASURING WAVEFRONT ABERRATION - An inspection device includes an objective lens that transmits inspection light reflected from a sample during inspection and measurement light from a point light source during aberration measurement, a first pupil relay lens that transmits the inspection light and the measurement light, a second pupil relay lens in which an intermediate imaging plane is formed between the second pupil relay lens and the first pupil relay lens, a diffraction grating disposed between the first pupil relay lens and the intermediate imaging plane and that diffracts the measurement light, a point diffraction interferometry plate disposed within a depth of focus of the intermediate imaging plane and that selectively transmits the diffracted light, a first detector that detects an image of the sample, and a second detector that detects a fringe image of the measurement light. | 2022-08-25 |
20220268710 | CONTINUOUS DEGENERATE ELLIPTICAL RETARDER FOR SENSITIVE PARTICLE DETECTION - An inspection system may include an illumination source to generate an illumination beam, illumination optics to direct the illumination beam to a sample at an off-axis angle along an illumination direction, and collection optics to collect scattered light from the sample in a dark-field mode, where the scattered light from the sample includes surface haze associated with light scattered from a surface of the sample, and where at least a at least a portion of the surface haze has elliptical polarizations. The system may further include pupil-plane optics to convert the polarizations of the surface haze across the pupil to linear polarization that is aligned parallel to a selected haze orientation direction. The system may include a linear polarizer to reject the surface haze aligned parallel to this haze orientation direction and a detector to generate a dark-field image of the sample based on light passed by the linear polarizer. | 2022-08-25 |
20220268711 | SCATTERING TOMOGRAPHY DEVICE AND SCATTERING TOMOGRAPHY METHOD - A scattering tomography device includes: a transmitting antenna element that transmits radio waves into an object from outside; a receiving antenna element that receives, outside the object, scattered waves of the radio waves transmitted into the object; and an information processing circuit that generates an image of the interior of the object using measurement data indicating the scattered waves received by the receiving antenna element. The information processing circuit: derives, using the measurement data, a relational expression that satisfies an equation whose solution is a scattering field function; derives, using the relational expression, an image function that is for generating the image and includes one or more parameters indicating a correspondence between a change in frequency of the radio waves and a change in a dielectric constant of the object in accordance with Debye relaxation; and generates the image using the image function. | 2022-08-25 |
20220268712 | SYSTEMS AND METHODS OF COMPARATIVE COMPUTED TOMOGRAPHY (CT) FOR QUALIFICATION OF COMMERCIAL GRADE ITEMS - A method of qualifying physical components using computed tomography (CT) includes obtaining qualified CT data from a CT scanner for at least one qualified physical component. Qualification data is generated based on the qualified CT data, where the qualification data defines a qualification envelope. Candidate CT data is obtained from the CT scanner for a candidate physical component. Comparison data is then generated based on the candidate CT data and the qualification data, where the comparison data indicates whether the candidate CT data is within the qualification envelope defined by the qualification data. An acceptance signal is generated if the comparison data meets acceptance criteria | 2022-08-25 |
20220268713 | Systems and Methods for Eliminating Cross-Talk Signals in One or More Scanning Systems Having Multiple X-Ray Sources - The present specification describes a system for eliminating X-ray crosstalk between a plurality of X-ray scanning systems and passive radiation detectors. The system includes a frequency generator for generating a common operational frequency, a high-energy X-ray source or scanning system coupled with the frequency generator for receiving the common operational frequency and configured to modify the pulse repetition frequency of the high-energy X-ray source or scanning system in order to synchronize with the common operational frequency and a low-energy X-ray scanning system and/or passive radiation detection system coupled with the frequency generator for receiving the common operational frequency and having a processing module configured to remove data associated with the common operational frequency at an instance of time if the high-energy X-ray source or scanning system has emitted X-rays at the instance of time. | 2022-08-25 |
20220268714 | Full Beam Metrology For X-Ray Scatterometry Systems - Methods and systems for characterizing dimensions and material properties of semiconductor devices by full beam x-ray scatterometry are described herein. A full beam x-ray scatterometry measurement involves illuminating a sample with an X-ray beam and detecting the intensities of the resulting zero diffraction order and higher diffraction orders simultaneously for one or more angles of incidence relative to the sample. The simultaneous measurement of the direct beam and the scattered orders enables high throughput measurements with improved accuracy. The full beam x-ray scatterometry system includes one or more photon counting detectors with high dynamic range and thick, highly absorptive crystal substrates that absorb the direct beam with minimal parasitic backscattering. In other aspects, model based measurements are performed based on the zero diffraction order beam, and measurement performance of the full beam x-ray scatterometry system is estimated and controlled based on properties of the measured zero order beam. | 2022-08-25 |
20220268715 | CRYSTAL DEFECT OBSERVATION METHOD FOR COMPOUND SEMICONDUCTOR | 2022-08-25 |
20220268716 | PORTABLE ASSESSMENT KIT AND METHOD FOR MEASURING METAL CONTENT OF AQUEOUS SOLUTION - A portable assessment kit for measuring metal content of an aqueous solution. The kit includes a sample container having an opening at its first end for containing a sample of the aqueous solution, a disc holder having a first end for detachably attaching the disc holder to the opening of the sample container, a pre-concentration disc for collecting metals and being arrangeable in the disc holder. The pre-concentration has a first side and a second side. The kit further includes means for pumping the sample through the opening of the sample container to the first side of the pre-concentration disc and a measurement device for measuring amount of metals in the pre-concentration disc. | 2022-08-25 |
20220268717 | ENERGY DISPERSIVE X-RAY FLUORESCENT SPECTROMETER, EVALUATION METHOD, AND EVALUATION PROGRAM - Provided is an energy-dispersive X-ray fluorescence spectrometer capable of easily determining reliability of a result of quantitative analysis and quickly recognizing an abnormality in measurement conditions, an X-ray fluorescence spectrometer, a sample, preprocessing for the sample, or the like. The energy-dispersive X-ray fluorescence spectrometer includes: a spectrum acquisition unit configured to acquire a spectrum; a calculation unit configured to execute quantitative analysis for an element included in the sample based on a peak included in the spectrum; and an evaluation unit configured to calculate a plurality of evaluation values obtained using different calculation methods for a series of processes, being the process of acquiring the spectrum by the spectrum acquisition unit, and the process of executing the quantitative analysis by the calculation unit, and to calculate a comprehensive evaluation value obtained by composing the plurality of evaluation values. | 2022-08-25 |
20220268718 | DIAMOND AUTHENTICATION PROCESS AND SYSTEM THEREFORE - A process of determining the type of a diamond of unknown type, said process including the steps of (i) applying a laser input signal to a diamond of unknown type such the NV | 2022-08-25 |
20220268719 | METHOD FOR DETECTING VOID IN CONCRETE COMPOSITE MEMBER COVERED WITH STEEL PLATE USING THERMAL IMAGE, AND METHOD FOR MANAGING CONSTRUCTION OF CONCRETE COMPOSITE MEMBER COVERED WITH STEEL PLATE BY APPLYING SAME - The present invention relates to a method for detecting a void in a concrete composite member covered with a steel plate using a thermal image, and a method for managing the construction of a concrete composite member covered with a steel plate by applying same. According to the present invention, since the presence of the void is determined based on the steel plate surface temperature measured using the thermal image during the construction of the concrete composite member covered with the steel plate, the void generation may be precisely expected. | 2022-08-25 |
20220268720 | SENSOR DEVICE, AND METHOD FOR MANUFACTURING SENSOR DEVICE - A sensor device configured to accurately identify a volatile compound from water vapor even at high humidity, and a method for manufacturing the sensor device are provided. The sensor device includes a measuring transducer including a pixel array on which volatile compounds and water vapor are condensed and a sensitive porous dielectric layer provided in a form of a plurality of spheres constituting the pixel array, a temperature controller provided around the pixel array, and configured to control temperature of each of pixels constituting the pixel array and temperature of the pixel array, a detection device connected to the measuring transducer, and configured to detect a response pattern of the volatile compounds through the pixel array, an analyzer configured to process, classify, and store the response pattern, a stimulating source connected to the measuring transducer, and configured to stimulate the measuring transducer, and at least one processor. | 2022-08-25 |
20220268721 | DETERMINING A TEMPERATURE COEFFICIENT VALUE OF A RESISTOR - The present disclosure relates to circuitry for determining a temperature coefficient value of a resistor. The circuitry comprises circuitry for supplying an AC current signal to the resistor, circuitry for measuring a first voltage across the resistor when the AC current signal is supplied; and processing circuitry configured to determine the temperature coefficient value based on the first voltage. | 2022-08-25 |
20220268722 | GAS DETECTION DEVICE WITH A DETECTOR AND WITH A COMPENSATOR AND GAS DETECTION PROCESS WITH SUCH A GAS DETECTION DEVICE - A gas detection device and a gas detection process monitor an area for a combustible target gas. A detector ( | 2022-08-25 |
20220268723 | SENSOR - According to one embodiment, a sensor includes a first sensor part. The first sensor part includes a first counter electrode, a first movable electrode, a first layer, and a first intermediate layer. The first movable electrode is between the first counter electrode and the first layer. The first intermediate layer is between the first movable electrode and a portion of the first layer. A first gap is located between the first counter electrode and the first movable electrode. A distance between the first counter electrode and the first movable electrode changes according to a concentration of a gas around the first sensor part. The first layer includes a crystal. The first intermediate layer is amorphous, or a crystallinity of the first intermediate layer is less than a crystallinity of the first layer. A width of the first layer is greater than a width of the first intermediate layer. | 2022-08-25 |
20220268724 | PROCESS FOR PRODUCING BANDS FOR BIOMEDICAL SENSORS AND BANDS PRODUCED ACCORDING TO THIS PROCESS - Process for producing bands for biological measurements on the basis of flexible circuits on a carrier strip, provided with a flexible insulating substrate provided, on at least one of its faces, with conductive tracks, contact pads and electrodes, includes the application, to said face, of masking means leaving the contact pads and/or the electrodes of the band visible and the selective deposition of a layer of noble metal on said contact pads and electrodes through said masking means. | 2022-08-25 |
20220268725 | Deaerator and Electrolyte Measurement System - To enable efficient substance measurement, this invention is characterized in that the invention comprises a first hollow fiber ( | 2022-08-25 |
20220268726 | WATER QUALITY MEASURING SYSTEM - A water quality measuring system includes a first introduction section for introducing rearing water as a sampling target, and a first adding section which adds an acid to the rearing water introduced by the first introduction section, and a nitrous acid sensor whose measurement target is nitrous acid and which measures the measurement target concentration of the rearing water to which the acid has been added by the first adding section. The water quality measuring system includes a second adding section which adds a base to the rearing water introduced by the first introduction section, and an ammonia sensor whose measurement target is ammonia and which measures the measurement target concentration of the rearing water to which the base has been added by the second adding section. | 2022-08-25 |
20220268727 | SENSOR ELEMENT - A sensor element includes: an element base including: a ceramic body made of an oxygen-ion conductive solid electrolyte, and having an inlet at one end portion thereof; at least one internal chamber located inside the ceramic body, and communicating with the inlet under predetermined diffusion resistance; an electrochemical pump cell including an electrode located on an outer surface of the ceramic body, an electrode facing the internal chamber, and a solid electrolyte located therebetween; and a heater buried in the ceramic body; and a porous leading-end protective layer surrounding a first range at least including a leading end surface and a region to be coped with water-induced cracking specified in advance. A single heat insulating space is interposed between the leading-end protective layer and a whole side surface of the element base at least in the above region. | 2022-08-25 |
20220268728 | EXTENSIBLE, MULTIMODAL SENSOR FUSION PLATFORM FOR REMOTE, PROXIMAL TERRAIN SENSING - A sensor assembly includes a housing and multiple sensor array segments. A first sensor array segment includes an antenna. A second sensor array segment has a soil temperature sensor, an electrical conductivity (EC) sensor, a moisture sensor, an ion-sensitive field effect transistor (ISFET) nitrate sensor for detecting nitrates in adjacent soil, an ISFET phosphate sensor for detecting phosphates in adjacent soil, an ISFET potassium sensor for detecting potassium in adjacent soil, and an ISFET pH sensor for detecting pH in adjacent soil, and a reference electrode electrically coupled to the first sensor array segment and to the second sensor array segment. The first sensor array segment and the reference electrode can be disposed on opposite sides of the second sensor array segment. | 2022-08-25 |
20220268729 | MEASURING ION STRENGTH USING CLOSED-LOOP ELECTROCHEMICAL PH MODULATION - Provided is a method for monitoring a change of ion strength in a sample solution by a closed-loop device that provides continuous cycling of electrochemical pH modulation between pre-defined pH values. In particular, the change of ion strength may be induced by a chemical reaction and may ultimately alter the electrical control parameters of the closed-loop device. By measuring such electrical control parameters, the degree and progress of the underlying chemical reaction may be monitored. | 2022-08-25 |
20220268730 | Relative Quantitation Using Electrochemical Mass Spectrometry - A method for relative quantification of organic and biological compounds by electrochemical mass spectrometry is disclosed. The method involves using electrochemistry (EC) in a mass spectrometry (MS)-based relative quantitative analysis. In this method, isotope-labeled standards or running calibration curves are not employed. A quantification method could include the steps of subjecting a sample analyte to liquid chromatography or electrophoresis separation, followed by an electrochemical oxidation or reduction in an electrochemical cell, and then mass spectrometric detection. | 2022-08-25 |
20220268731 | METHODS OF PARTICLE MANIPULATION AND ANALYSIS - Methods described herein, in some embodiments, permit extraction of particle structural and/or surface charge data from gradient induced particle motion in channels. In one aspect, a method of manipulating particle motion comprises introducing a fluid into a channel, the fluid comprising particles, and driving particle accumulation to a preselected location in the channel by setting advective velocity of the fluid to offset diffusiophoretic mobility of the particles at the preselected location. | 2022-08-25 |
20220268732 | NANOZYMES WITH RADICAL-SCAVENGING CAPPING AGENTS AND METHODS OF DETECTION THEREWITH - Nanozymes capped with a radical-scavenging capping agent are disclosed for use in biosensing assays with improved sensitivity. The radical-scavenging capping agent facilitates the capture and retention of one or more radicals for enhancing a catalytic reaction. In some example embodiments, the nanozyme capped by the radical-scavenging capping agent is capable of catalyzing the decomposition of hydrogen peroxide or molecular oxygen. The capped nanozymes may be incorporated with an electrode, such as the working electrode of an electrochemical sensor, for achieving enhanced catalytic activity and a lower limit of detection. In some example embodiments, the radical-scavenging capping agent is or includes thiocyanate. A rapid ethanol detection device and associated method are described in which the working electrode of an electrochemical sensor is modified by a peroxidase-mimetic nanozyme capped with a radical-scavenging capping agent for the enhanced generation of a reduction current associated with the decomposition of hydrogen peroxide. | 2022-08-25 |
20220268733 | EVALUATION OF GASEOUS AND SOLID BYPRODUCTS FROM CHEMICAL REACTIONS - The invention relates to a method and apparatus for evaluating reaction molecular byproducts of pyrotechnic reactions. A closed calorimetry bomb holds pyrotechnic material, which is detonated by a charge. The calorimetry bomb is vented directly into a gas chromatography machine, where gas phase molecules are separated based on their polarity. The separated molecules are then injected into a mass spectrometer and characterized by their mass fragmentation. The remaining residual solids within the bomb are extracted and injected into a liquid chromatography instrument where they are separated by their polarity. The separated molecules are then injected into a mass spectrometer and characterized by their mass fragmentation pattern. The method provides a complete picture of the reaction pathways and products to aid in regulatory compliance of incorporating energetic materials into real-world applications, particularly those in the family of PFAS containing compositions. | 2022-08-25 |
20220268734 | EDDY CURRENT SENSOR HAVING IMPROVED CRACK DETECTION CAPABILITY, AND EDDY CURRENT INSPECTION DEVICE INCLUDING SAME - The present invention relates to an eddy current sensor for deriving an eddy current and sensing the derived eddy current in order to detect a crack in a battery cell, the eddy current sensor comprising: a core unit in which a coil is wound around a magnetic member; and a case for accommodating the core unit of which there are at least two, and which are respectively arranged so that the central axis of the coil is oriented in the thickness direction of the battery cell. The eddy current sensor of the present invention enables one-point sensing, thereby improving crack detection capability without a non-inspection area while having high detection resolution. | 2022-08-25 |
20220268735 | APPARATUS AND METHOD FOR INSPECTION OF A MATERIAL - A method of inspecting a material includes examining a surface of a test material with an eddy current sensor and applying an X-ray fluorescence analysis to the surface of the test material at the same location at which the eddy current examination was performed. | 2022-08-25 |
20220268736 | CONTINUOUS WAVE SONIC ANALYZER - A gas analyzer uses continuous sonic signals through a conduit to determine the composition of a gas in the conduit. A transmitting transducer drives sonic signals at a fixed frequency and a second transducer receives the sonic signals. The phase shift between two signals corresponds to the speed of sound through the gas and is related to the composition of the gas. The electronic versions of these signals are processed by lowering, or dividing, the fixed frequency which expands the range of phase shift measurement and allows the determination of an expanded range for the gas composition. In an ozone generation system, the gas analyzer is highly suitable for determining the composition of gases derived from air as a gas of known composition and a calibration point. | 2022-08-25 |
20220268737 | Method, Equipment and Readable Medium for Evaluating Structural Strength of Fiber and Nanosized Materials Reinforced Concrete - A method, an equipment, and a computer readable medium for evaluating structural strength of fiber and nanosized materials reinforced concrete are provided. The method includes: obtaining a sound velocity of a fiber and nanosized materials reinforced concrete test block; deriving a structural compressive strength of the fiber and nanosized materials reinforced concrete test block according to the sound velocity and a relation between fiber and nanosized materials reinforced concrete structural compressive strength and fiber and nanosized materials reinforced concrete sound velocity; determining strengths of various parts of the fiber and nanosized materials reinforced concrete test block based on measured parameters and recorded design parameters of the test fiber and nanosized materials reinforced concrete, and evaluating deviations of the strengths of the respective parts from the structural compressive strength. The partial design strengths and the deviations from the structural compressive strength may be evaluated and corrective measures may be given. | 2022-08-25 |
20220268738 | ULTRASONIC INSPECTION MARGIN CHECK FOR DESIGN AND MANUFACTURING - A method for quantitatively evaluating the expected ultrasonic inspectability of a designed part using ray tracing. First, a model of a part imported. Materials having different indices of refraction are selected for the part and an acoustic coupling medium. Then the following structures and positional relationships are defined: an ultrasonic transducer array comprising a plurality of elements, a position of the acoustic coupling medium between the transducer array and the part, and a plurality of positions of a transmit aperture relative to the part. For each defined position of the transmit aperture, a path of a respective ray is traced from a center of the transmit aperture through the part and then to a respective receive location on the transducer array. Also, a respective value of an inspectability margin is calculated based at least in part on a respective distance between a center of the receive aperture and the respective receive location. Each value of the inspectability margin is compared to a threshold value. | 2022-08-25 |
20220268739 | MULTI-MATERIAL INSPECTION SYSTEM AND VELOCITY MEASUREMENT METHOD OF CRITICALLY REFRACTED LONGITUDINAL WAVE BASED ON SINGLE-ANGLE WEDGES - A multi-material inspection system and velocity measurement method of critically refracted longitudinal wave based on single-angle wedges belong to the field of nondestructive testing of high-end equipment. The method includes the following steps: designing a transmitting wedge and a receiving wedge with the same inclination angle, and building phased array ultrasonic-based inspection systems of critically refracted longitudinal wave; estimating a longitudinal wave velocity range of a material to be tested, calculating and optimizing a phased array ultrasonic delay law, and building a relation between a longitudinal wave velocity and an amplitude of critically refracted longitudinal wave; reading and interpolating the arrival time of a received signal, and calculating a longitudinal wave velocity of the material to be tested; determining an optimal delay law, and exciting and receiving a critically refracted longitudinal wave. | 2022-08-25 |
20220268740 | Non-destructive Inspection Of Test Objects On A Workpiece - A method for non-destructive inspection of at least one test object on a workpiece includes the steps of: obtaining a theoretical position of each test object in relation to a testing robot; capturing an image of each test object to obtain image data; determining a real position of each test object in relation to the testing robot on the basis of the image data; and bringing a sensor carried by the testing robot in contact with each test object to obtain a respective test measurement. For the certain type of inspection where the test instrument needs to be brought in physical contact with the test object to be inspected, it is crucial to know the exact position of the test object. As soon as the approximate position of the test object is known an image of the test object can be captured, and the exact position of the test object can be extracted from the respective image data. | 2022-08-25 |
20220268741 | Probe Arrangement for a Testing System, and Testing System - A probe arrangement for a testing system includes a base carrier that defines a longitudinal direction, which can be oriented parallel to a testing direction, and a transverse direction, which can be oriented perpendicularly to the testing direction. The base carrier carries a plurality of probe holders which are arranged next to one another in a row in the transverse direction. Each probe holder has a first probe region, which is equipped with at least one first probe, and a second probe region, which is equipped with at least one second probe. Each probe region defines an effective testing width such that, during relative movement of the test subject with respect to the probe arrangement along the testing direction through the probe region, a testing track having the effective testing width can be tested in a gap-free manner. The first probe region and the second probe region are arranged so as to be offset in relation to one another parallel to the longitudinal direction and parallel to the transverse direction such that a first testing track covered by the first probe region transitions on one side in a gap-free manner into a second testing track covered by the second probe region of the same probe holder, and transitions on the opposite side in a gap-free manner into a second testing track covered by a second probe region of a directly adjacent probe holder. | 2022-08-25 |
20220268742 | COVER UNIT OF ULTRASONIC TRANSDUCER - A cover unit includes: a body to which an ultrasound generator adapted to generate ultrasound is coupled; first slits disposed at a lower portion of the body in the form of multiple rings having different radii and spaced apart from each other, the first slits having a first width; second slits depressed from an upper surface of the body to communicate with the first slits and having a second width smaller than the first width; third slits depressed from the upper surface of the body and each disposed between adjacent second slits, the third slits having a third width smaller than the first width; a bottom formed under the first slits; a first sidewall formed between adjacent first slits; and a second sidewall formed between the second slit and the third slit. | 2022-08-25 |
20220268743 | ULTRASONIC TESTING PROBE, COUPLANT DELIVERY SYSTEM, AND ULTRASONIC TESTING APPARATUS - An ultrasonic testing apparatus structured to perform an ultrasonic inspection on a workpiece. The ultrasonic testing apparatus comprises an ultrasonic testing probe structured to generate an ultrasonic output directed toward the workpiece and to receive an ultrasonic input from the workpiece that is responsive to the output; a couplant delivery system comprising a couplant supply, the couplant delivery system further comprising an actuator which, when operated, is structured to apply from the couplant supply an amount of a couplant to at least one of the workpiece and the ultrasonic testing probe; and a control apparatus electrically connected with the ultrasonic testing probe and with the couplant delivery system, the control apparatus being structured to receive the ultrasonic input and being further structured to operate the actuator. A couplant delivery system that is operable with an ultrasonic testing apparatus that is structured to perform an ultrasonic inspection on a workpiece. | 2022-08-25 |
20220268744 | COMBINED ANALYTIC TECHNIQUE FOR DIFFERENTIATING CHANGES TO STRUCTURES USING ACOUSTIC SIGNALS - Combinations of multiple analytic techniques may be used to identify changes to a structure based on changes in characteristics of acoustic signals traveling along the structure. Acoustic signals traveling along the structure may be monitored to detect changes in characteristics of the acoustic signal from baseline signal characteristics. The changes in characteristics of the acoustic signals may be processed using multiple analytic techniques to provide analyses of the change in time-domain, in frequency-domain, and in mixed time-frequency-domain. The change to the structure may be identified based on a combination of the results of the analysis in time-domain, in frequency-domain, and in mixed time-frequency-domain. | 2022-08-25 |
20220268745 | Chromatography System - A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium. | 2022-08-25 |
20220268746 | ZWITTERIONIC COMPOUNDS AS GAS CHROMATOGRAPHIC COLUMN STATIONARY PHASES - A gas chromatographic (GC) column using a zwitterionic compound and methods of use thereof are disclosed herein. The volatile free acids were observed to strongly retain on these zwitterionic compounds-based columns with excellent peak symmetry. By carefully tuning the structures of these zwitterionic compounds, different selectivity toward volatile free acids was demonstrated. These stationary phases possess a wide working range with thermal stabilities at higher temperatures. | 2022-08-25 |
20220268747 | SYSTEM FOR INTEGRATING MULTIPLE CHEMICAL SENSOR DATA TO DETECT AN UNMEASURED COMPOUND - Methods for determining the presence of an unmeasured chemical in an environment can include receiving a plurality of sensor readings from a plurality of chemical sensors, wherein each chemical sensor of the plurality of chemical sensors is configured to detect a different chemical, determining a cross-sensitivity pattern from one or more unmeasured chemicals in the plurality of sensor readings, comparing the cross-sensitivity pattern with one or more known chemical patterns, determining that the cross-sensitivity pattern matches at least one of the one or more known chemical patterns that correspond to one or more chemicals, and identifying one or more unmeasured chemicals based on determining that the cross-sensitivity pattern matches the at least one of the one or more known chemical patterns. | 2022-08-25 |
20220268748 | PORTABLE SYSTEM FOR MEASURING AND ANALYZING INDOOR AIR QUALITY AND METHOD THEREOF - The present invention discloses a portable system for measuring and analyzing indoor air quality and method thereof The system comprises an Internet Of Things (IOT) enabled sensor device ( | 2022-08-25 |
20220268749 | TRACKING AND AUDITING OF GHG EMISSIONS - One example provides a computing system configured to implement a greenhouse gas (GHG) tracking and auditing platform for tracking GHG emissions associated with a plurality of GHG entities, each GHG entity representing one or more of a GHG source and a GHG sink. The computing system comprises a logic subsystem and a data-holding subsystem comprising computer-readable instructions. The instructions are executable to receive sensor data over time from each sensor of one or more sensors, each sensor configured to sense data related to GHG emissions. The instructions are further executable to, for each time interval of a plurality of time intervals, determine a GHG emission amount based at least in part on the sensor data and store GHG emission data. The instructions are further executable to receive a request for a set of GHG emission data and in response to the request, output the set of GHG emission data. | 2022-08-25 |
20220268750 | INTEGRATION AND ACTIVE FLOW CONTROL FOR ENVIRONMENTAL SENSORS - A technique for monitoring and collecting environmental data is provided that supports acquisition and analysis of quality measurements of pollutants by sensors based on different technologies in an integrated manner. The system includes a primary substrate having a plurality of sensor modules, each sensor module configured to couple to a sensor, and a manifold having a plurality of flow hoods, each flow hood disposed on a top surface of a sensor and connected to another flow hood or component in the manifold. In some cases, the sensor modules are gas sensor modules, and the sensor is a gas sensor. The manifold thus provides a closed system through which a fluid sample can flow across a series of gas sensors in an actively controlled manner that enables independent flow control over each individual gas sensor while limiting exposure of the fluid sample to potential sources of contamination. | 2022-08-25 |
20220268751 | APPARATUS AND METHOD FOR MULTIMODE ANALYTICAL SENSING OF ITEMS SUCH AS FOOD - A multimode biological sample inspection apparatus and method is provided. The apparatus includes an illumination hardware arrangement comprising transmission and sensing hardware configured to inspect a biological sample using at least two modes from a group comprising a fluorescence imaging mode, a reflectance imaging mode, a scattering imaging mode, and a Raman imaging mode, and processing hardware configured to operate the illumination hardware arrangement according to a protocol comprising inspection settings of the at least two modes. The processing hardware receives scan results from the illumination hardware arrangement and identifies attributes of the biological sample by constructing a multidimensional dataset comprising at least one spatial dimension and at least one spectral dimension from the scan results and analyzing the multidimensional dataset. The processing hardware is configured to employ the attributes of at least one biological sample and alter the protocol. | 2022-08-25 |
20220268752 | CONCENTRATION MONITORING SYSTEM, CONCENTRATION MANAGEMENT SYSTEM, AND CONCENTRATION MONITORING METHOD - Provided is a concentration monitoring system which allows continuous concentration monitoring of a processing tank. The concentration monitoring system is provided with a first cycle in which a sample of a processing liquid to which a chemical has been added is taken from a processing tank in which the processing liquid is stored and supplied to a concentration meter which measures the concentration of the chemical, a second cycle in which a chemical solution having a known concentration of the chemical is supplied to the concentration meter, and a control device which controls the first cycle to evaluate the concentration of the chemical in the processing tank on the basis of the concentration of the sample measured by the concentration meter and controls the second cycle to evaluate the precision of the concentration meter on the basis of the concentration of the chemical solution measured by the concentration meter. | 2022-08-25 |
20220268753 | SYSTEMS, SUBSYSTEMS AND METHODS FOR MEASURING WATER CHARACTERISTICS IN A WATER FACILITY - Systems and Methods for monitoring characteristics of a water sample taken from a water facility (WF), by using a first light source emitting light at a first wavelength, and an additional light source, emitting light at an additional wavelength which is distinctly different from the first wavelength; for each light source, performing a measurement of the water sample, using an optical sensor outputting updated sensor data and a spectral detector, outputting updated detector data; and determining adjustment properties for adjustment of an analysis model, used for ongoing determination of water characteristics such as the water turbidity level, based on comparison between the measurements for each of the light sources. | 2022-08-25 |
20220268754 | EARLY DETECTION OF E. COLI AND TOTAL COLIFORM USING AN AUTOMATED, COLORIMETRIC AND FLUOROMETRIC FIBER OPTICS-BASED DEVICE - A system for detecting the presence of | 2022-08-25 |
20220268755 | WATER SAMPLING IMMERSION PROBE - The present invention relates to a water sampling immersion probe ( | 2022-08-25 |
20220268756 | METHODS AND SYSTEMS FOR GENERATING AND APPLYING AGRONOMIC INDICES FROM MICROBIOME-DERIVED PARAMETERS - Methods and systems for generating agronomic indices and executing one or more actions in response to said agronomic indices at an agriculture site, the method comprising: receiving a set of samples associated with the agriculture site; generating a sample dataset upon processing the set of samples with a set of sample processing operations; generating a set of microbiome-associated features upon performing a set of transformation operations upon the sample dataset, wherein the set of microbiome-associated features comprises a first subset of taxonomic annotations, a second subset of functional annotations and a third subset of ecological indices; generating values of a set of agronomic indices based upon the set of microbiome-associated features; and executing an action for producing a desired outcome at the agriculture site, based upon the set of agronomic indices. | 2022-08-25 |
20220268757 | TEST PAPER BOX AND INTELLIGENT TOILET CONTAINING SAME - The present invention provides a test paper box and a smart toilet containing same. The test paper box comprises a support and a housing arranged at the outside of the support. The support comprises a base and an elongated cavity arranged at the base for storing test paper. The base is provided with a through hole arranged at a location corresponding to a bottom surface of the elongated cavity. A paper-receiving slot is arranged below the through hole. The paper-receiving slot is fixed to the bottom of the base to receive the bottommost piece of test paper exposed from the elongated cavity, and the paper-receiving slot is provided with a paper outlet. The test paper box can be attached and detached conveniently, delivers test paper smoothly, can be replaced easily, has low costs, and is suitable for smart toilets. | 2022-08-25 |
20220268758 | MODULAR HAND-HELD POINT OF CARE TESTING SYSTEM - A modular hand-held point of care testing system, which includes a plurality of different assay adapters configured to receive a plurality of different assay devices that perform assays on one or more samples; a shared door that that interchangeably receives the plurality of different assay adapters; wherein at least two of the plurality of assay adapters or at least two of the assay devices comprise different identifiers that distinguish the assays from each other; an apparatus comprising a portable frame configured to interchangeably receive the shared door and a means for decoding the different identifiers when received by the frame; and a means for reading assay results. | 2022-08-25 |
20220268759 | TECHNIQUES FOR DETECTION OF MOLECULES IN A SAMPLE USING FRACTIONIZATION AND SELECTIVE CAPTURE - An exemplary analysis system may include a fractionization device configured to separate a sample into various molecules that may be introduced to a sampling chamber having a molecule collector disposed therein. The molecule detector may be configured such that molecules of interest produced during fractionization adhere to the molecule collector. A heating element may introduce heat within the sampling chamber, causing release of at least a portion of the molecules adhered to the molecule collector. An analysis device (e.g., a mass spectrometer, a terahertz (THz) spectrometer, etc.) may detect the presence of the one or more molecules of interest from among molecules produced during the fractionization and generate an output representative of the identified molecule(s) of interest. The output may include information that quantitates a concentration of the molecule(s) of interest within sample. | 2022-08-25 |
20220268760 | ATRIAL CARDIAC MICROTISSUES FOR CHAMBER-SPECIFIC ARRHYTHMOGENIC TOXICITY RESPONSES - The invention provides a robust in vitro 3D atrial tissue platform made from human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes. The platform is useful for evaluating atrial-specific chemical responses experimentally and computationally. | 2022-08-25 |
20220268761 | THERAPY MONITORING UNDER TREATMENT WITH AN ANTI-ADRENOMEDULLIN (ADM) BINDER - Subject matter of the present invention is a method for monitoring a therapy in a subject, wherein the subject is under treatment with an anti-Adrenomedullin (ADM) binder selected from the group comprising an antibody, antibody-fragment and/or non-Ig scaffold, comprising determining the level of a fragment of pre-pro-Adrenomedullin selected from the group comprising Midregional Proadrenomedullin (MR-proADM), C-terminal Proadrenomedullin (CT-proADM) and/or Proadrenomedullin N-terminal 20 peptide (PAMP) or fragments thereof in a bodily fluid obtained from said subject; and correlating the level of said fragment of pre-pro-Adrenomedullin with the subject's clinical/medical status of health and/or the risk for an adverse outcome and/or the requirement for adapting therapeutic measures. | 2022-08-25 |
20220268762 | METHODS, SYSTEMS, AND COMPUTER-READABLE MEDIA FOR PREDICTING A CANCER PATIENT'S RESPONSE TO IMMUNE-BASED OR TARGETED THERAPY - Methods, systems, and computer-readable media for predicting a patient's response to immune based or target therapy are described herein. An example computer-implemented method includes generating a model configured to represent dynamics and interactions among normal T cells, engineered cells, and tumor cells, where the model includes a plurality of cell population compartments. The computer-implemented method also includes receiving pre-treatment patient data for a cancer patient, and receiving post-treatment patient data for the cancer patient. Each of the pre-treatment patient data and the post-treatment patient data includes a measure of at least one of tumor volume, total lymphocytes, memory T cells, memory engineered cells, tumor killing cells, or antigen-presenting tumor cells. The computer-implemented method further includes quantitatively predicting the cancer patients response to the immune-based or targeted therapy using the model, the pre-treatment patient data, and the post-treatment patient data. | 2022-08-25 |
20220268763 | HEMOLYTIC REAGENT, REAGENT KIT, AND METHOD FOR CLASSIFYING WHITE BLOOD CELLS - Disclosed is a hemolytic reagent comprising a nonionic surfactant represented by formula (I) below: | 2022-08-25 |
20220268764 | FABRICATION OF FLUORESCENT NANOPARTICLES AND THEIR CONJUGATES FOR IN VITRO AND IN VIVO DIAGNOSTICS - Provided are fluorescent nanoparticles and their conjugates and methods of using the same for in vivo and in vitro diagnostics and other applications. In some embodiments, provided are fluorescent nanoparticles with high solid-state absolute quantum yield. In some embodiments, provided are methods of manufacturing such nanoparticles. Nanoparticles may comprise monomers, such as styrene, and fluorophores, such as AlEgen™ Bright Green. | 2022-08-25 |
20220268765 | METHODS AND KITS FOR UNIVERSAL CALIBRATION OF LATERAL FLOW TESTING - The present disclosure provides methods and kits for detecting an analyte within a sample by using lateral flow testing. Specifically, the present disclosure relates to use of an analyte specific calibration curve for determining quantity of an analyte within a complex sample, wherein the sample is purified/enriched by using a sample preparation method including an affinity resin. The present disclosure further relates to kits including an optional affinity resin, a lateral flow test, and an algorithm corresponding to the analyte specific calibration curve. | 2022-08-25 |
20220268766 | HORMONE MASS SPECTROMETRIC DETECTION METHOD BASED ON ANTIBODY-COUPLED MAGNETIC BEADS ENRICHMENT TECHNOLOGY - A hormone mass spectrometric detection method based on antibody-coupled enrichment technology. The method includes the following steps: coupling antibodies and magnetic beads, adding a high-concentration methanol solution, removing endogenous hormone small molecule compounds carried on the antibodies by vortex, then restoring the activity of the antibodies to obtain antibody magnetic beads that can enrich hormone small molecule compounds. The antibodies are immobilized by magnetic beads and cooperate with the 80% methanol aqueous solution to elute hormone small molecule compounds, and then the hormone small molecule compounds are tested by mass spectrometry, thereby improving the specificity of test. | 2022-08-25 |
20220268767 | NANOPARTICLES FOR DETECTION OF BACTERIA CELLS AND METHODS OF PREPARATION THEREOF - The present disclosure relates, in general terms, to nanoparticles which are characterised by having a photoluminescent amorphous core and a surface is functionalised with at least a carbohydrate. The present disclosure also relates to methods of forming and functionalising the nanoparticles and a photoluminescence assay comprising the nanoparticles for quantifying a sample comprising bacterial cells. | 2022-08-25 |
20220268768 | STRUCTURE AND METHODS FOR DETECTION OF SAMPLE ANALYTES - Provided herein are structures and methods for detecting one or more analyte molecules present in a sample. In some embodiments, the one or more analyte molecules are detected using one or more supramolecular structures. In some embodiments, the supramolecular structures facilitate binding of a single detector molecule. In some embodiments, the stable state supramolecular structures are configured to provide a signal for analyte molecule detection and quantification. In some embodiments, the signal correlates to a DNA signal, such that detection and quantification of an analyte molecule comprises converting the presence of the analyte molecule into a DNA signal. | 2022-08-25 |
20220268769 | QUARTZ CRYSTAL MICROBALANCE WITH PLASMONIC SENSING CAPACITY - A quartz crystal microbalance (QCM) sensor is proposed. The QCM sensor comprises a piezoelectric substrate and at least two electrodes in contact with the substrate to induce shear deformations therein through the inverse piezoelectric effect. The substrate has a sensing surface, and, on that surface, a pattern of plasmonic nanoparticle accumulations protruding from the surface. Each accumulation of nanoparticles comprises a plurality of plasmonic nanoparticles arranged about a hump. Plasmonic hot spots are present between neighbouring accumulations of the pattern that are separated a distance that amounts to or to less than the average diameter of the accumulations of the pattern. | 2022-08-25 |
20220268770 | 3D-1D MULTIDIMENSIONAL CANCER-ON-A-CHIP - The present invention relates to an apparatus for analyzing single tumor cells, said apparatus comprising a hydrogel-based polymeric microcapsule for entrapping cells and a hydrogel having on its surface a single cell migration path being formed by one or more extracellular matrix proteins and/or one or more polymers comprising RGD peptides or proteins, wherein the polymeric microcapsule and the path are placed in the apparatus such that upon the release of cells from the polymeric microcapsule a single tumor cell can migrate from the polymeric microcapsule on the path. | 2022-08-25 |
20220268771 | COMPOSITIONS AND METHODS FOR LYME DISEASE - Provided herein are, inter alia, methods and kits for diagnosing post-treatment Lyme disease syndrome (PTLDS) or Lyme disease in a subject. | 2022-08-25 |
20220268772 | Mass Spectrometry-Based Detection Of Mycotoxins In Meat | 2022-08-25 |
20220268773 | FLOW CYTOMETRY EVALUATION FOR UNASSOCIATED NON-ENVELOPED VIRAL PARTICLES - A method for flow cytometry evaluation of unassociated non-enveloped viral particles having a non-enveloped viral capsid includes preparing a fluorescently-stained fluid sample in which at least one fluorescent staining step is performed at an acidic pH in an acidic pH range and then subjecting the fluorescently-stained fluid sample to flow cytometry evaluation. A kit includes a plurality of sealed container with a first sealed container containing a fluorescent stain composition and a second sealed container including an aqueous dilution liquid at an acidic pH. | 2022-08-25 |
20220268774 | METHOD OF ELEVATING PREDICTION ACCURACY OF GROUPING SUBJECTS WITH SEVERE DENGUE INFECTION - The present invention relates to a method of elevating prediction accuracy of grouping subjects with severe dengue infection. In the method, a non-structural protein 1 (NS1) and an endogenous anti-NS1 antibody of dengue virus in an ex vivo biological specimen are detected and crossly compared, leading in reduce of false negative rates of testing results, as well as elevating grouping accuracy of patients with severe dengue infection. | 2022-08-25 |
20220268775 | SOLUBLE PROGRAMMED CELL DEATH PROTEIN-1 AS A BIOMARKER IN CANCER PATIENTS - Disclosed herein are methods for selecting cancer patients for autologous cancer vaccine therapy and methods for predicting survival of cancer patients after autologous cancer vaccine therapy comprising, measuring the level of soluble programmed cell death protein-1 (sPD-1) in the blood of the patient. | 2022-08-25 |
20220268776 | BIOMARKER PANEL FOR DIAGNOSING PANCREATIC CANCER AND USE THEREOF - The present invention relates to a biomarker for diagnosing pancreatic cancer and use thereof. The marker according to the present application can significantly predict or determine, through a 14-multimarker panel, the onset likelihood, early diagnosis, and severity of pancreatic cancer or precancerous lesions of pancreatic cancer, and can be used in research on the tumorigenesis of pancreatic cancer. | 2022-08-25 |
20220268777 | ANTIGEN AND ANTIBODIES PREPARED BASED ON PADI4 SERVING AS TUMOR MARKER, AND APPLICATION THEREOF - An antigen and antibodies prepared based on peptidylarginine deiminase (PADI4) serving as a tumor marker, and application thereof are disclosed. The antigen has an amino acid sequence shown as SEQ ID NO. 1. Specific antibodies prepared by using the antigen are also disclosed. The protein PADI4 monoclonal antibodies include a protein PADI4 monoclonal antibody coated onto an ELISA plate and a biotin-labeled protein PADI4 monoclonal antibody. A kit prepared by using the antibodies of the present disclosure can effectively and stably determine a protein PADI4 level of a human serum, and has a broad spectrum, detectability, and high test repeatability. | 2022-08-25 |
20220268778 | HIGH THROUGHPUT ANALYSIS AND SORTING, AND SAMPLING INTERFACE AND ASSEMBLY FOR HIGH THROUGHPUT ANALYSIS AND SORTING - A method of analyzing and/or sorting selected cells or other biological components, for example for cell-based therapy, includes sampling a sample with an open end of a probe to obtain a fluid stream with the sample in it. The probe with the open end also has a fluid supply to convey fluid to the open end, and a fluid exhaust to convey the fluid stream away from the open end. The method then includes conveying the fluid stream to a flow cytometer and analyzing the fluid stream by flow cytometry; and/or separating it into at least two components. An apparatus with the probe connected to the flow cytometer may support this method. The method can provide for sampling of multiple samples efficiently, in particular to select cells for cell-based therapies. | 2022-08-25 |
20220268779 | METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME - Methods of analyzing glycosylated biomolecules include the steps of producing a deglycosylation mixture of biomolecules deglycosylated by natural or synthetic enzymatic or chemical techniques; providing a reagent solution having a labeling reagent in a polar aprotic, non-nucleophilic organic solvent; and mixing the deglycosylation mixture with the reagent solution in an excess of labeling reagent to produce derivatized glycosylamines. The method steps can be carried out purposefully without depletion of protein matter. A quenching solution can be added to the reaction mixture so that the pH of the reaction mixture is shifted to above 10. The yield of derivatized glycosylamines can be in an amount of about 80 to about 100 mole percent of the reaction mixture with minimal overlabeling, less than 0.2 mole percent. The derivizated glycosylamines can be separated from the reaction mixture and detected by chromatographic detection, fluorescence detection, mass spectrometry (“MS”), or Ultra Violet (“UV”) detection and/or a combination thereof. | 2022-08-25 |
20220268780 | METHODS OF PREDICTING ENDOMETRIAL RECEPTIVITY - The present invention relates to methods of predicting endometrial receptivity for embryo implantation in a subject, the method comprising determining a level of podocalyxin in endometrial epithelial cells in the subject. The present invention also relates to methods of monitoring epithelial receptivity and improving epithelial receptivity. | 2022-08-25 |
20220268781 | PREECLAMPSIA BIOMARKERS AND RELATED SYSTEMS AND METHODS - Disclosed herein are methods, kits, tests, and systems for detecting, predicting, monitoring, or ruling out preeclampsia in pregnant women. Also provided herein are novel diagnostic markers, methods of data analysis, assay formats, and kits employing such markers to improve one or more characteristics of a test for identifying or ruling out preeclampsia based on biomarkers from patient samples. | 2022-08-25 |
20220268782 | METHODS FOR PREDICTING AND TREATING CARDIAC DYSFUNCTION - Ageing myocardium undergoes structural and functional changes characterized by progressive cardiomyocyte hypertrophy, interstitial fibrosis and inflammation ultimately leading to diastolic and systolic dysfunction. Whilst most focus has been placed on established risk factors such as dyslipidaemia, hypertension and obesity in accelerating cardiac ageing, a potential role for amino acids has received little attention. Here the inventors show that increased phenylalanine (PA) levels induced in vitro cytosolic oxidative stress and senescence whilst in vivo led to senile-like cardiac deterioration in young mice. Moreover, they demonstrated that hepatic PA catabolism declined with age in a p21-dependent manner, whilst p21 deficiency prevented age-related cardiac dysfunction. Finally, the inventors found that Pah cofactor BH4 reversed the age-related rise in plasma PA levels and senile cardiac alterations. These observations have immediate implications for promoting cardiac health and healthspan and suggest that phenylalanine can be used as a biomarker and biotarget of cardiac dysfunction. | 2022-08-25 |
20220268783 | METHODS FOR PEPTIDE MAPPING OF ADENO-ASSOCIATED VIRUS (AAV) PROTEINS - The present disclosure relates to a method of characterizing proteins in a sample. The method includes: removing non-ionic surfactant from the sample via denaturing size-exclusion chromatography to form a denatured sample; eluting the denatured sample via liquid chromatography to collect fractions of the sample, wherein the fractions of the sample include a protein fraction; lyophilizing the protein fraction to increase protein concentration; reconstituting the lyophilized protein fraction with a buffer comprising a surfactant to denature the protein; digesting the denatured protein fraction with an enzyme; and analyzing the digested protein fraction. | 2022-08-25 |
20220268784 | USING MASS SPECTROMETRY TO IDENTIFY ENDOMETRIOSIS TISSUE - In a general aspect, methods and devices are provided for using mass spectrometry to identify endometriosis. In some aspects, a fixed or discrete volume of a solvent is applied to a tissue site including possible endometriosis tissue. The applied solvent is collected to obtain a liquid sample. The liquid sample is subjected to mass spectrometry analysis. The liquid sample is collected from a tissue site in vivo during a medical procedure. The mass spectrometry data are analyzed to identify whether the tissue site comprises endometriosis. | 2022-08-25 |
20220268785 | FACILE SAMPLE PREPARATION FOR QUANTITATIVE SINGLE-CELL PROTEOMICS - Disclosed are compositions and methods for performing a proteomic analysis. Particularly disclosed are compositions and methods for preparing a sample for quantitative single-cell proteomics. | 2022-08-25 |
20220268786 | METHOD FOR ASSISTING DETERMINATION OF EXACERBATION RISK OF COVID-19 - Disclosed is a method for acquiring information on exacerbation risk of COVID-19, comprising measuring IgM antibody against S antigen of SARS-CoV-2 contained in a specimen collected from a subject infected with SARS-CoV-2 or a subject suspected of suffering from COVID-19, wherein a value obtained by the measurement of IgM antibody serves as an index of exacerbation risk of COVID-19 of the subject. | 2022-08-25 |
20220268787 | ANTIBODY SPECIFICALLY BINDING TO WRS PROTEIN, AND USE THEREOF - The present invention relates to an antibody specifically binding to a tryptophanyl-tRNA synthetase (WRS) protein and, more specifically, to: an antibody, or a fragment of the antibody, specifically binding to a polypeptide of an amino acid sequence represented by SEQ ID NO: 2 in a WRS protein; a polynucleotide encoding the antibody and a vector comprising same; a cell transformed using same; and a use thereof. | 2022-08-25 |
20220268788 | TEMPORAL TRAUMATIC BRAIN INJURY BIOMARKERS AND METHODS OF USE THEREOF - A unique pipeline is employed for biomarker discovery that entailed domain antibody phage display, next generation sequencing analysis, and nanotechnology strategies to generate antibody mimetics are disclosed. Also disclosed are the temporal biomarkers of traumatic brain injury and their methods of use. In some embodiments, the temporal biomarkers are synthetic peptides comprising the HCDR3 sequences identified using the disclosed pipeline. In some aspects, the synthetic peptides have less than 30 amino acid residues and comprise a biotin scaffold that is linked to the HCDR3 sequences. | 2022-08-25 |
20220268789 | MONOCLONAL ANTIBODY AGAINST AMYLOID BETA, AND METHOD FOR MEASURING AMYLOID BETA-RELATED PEPTIDE USING SAID ANTIBODY - The present invention provides a novel anti-Aβ antibody capable of detecting an Aβ related peptide, a method for measuring an Aβ related peptide in a biological sample by immunochemically using the above-mentioned novel anti-Aβ antibody, and a kit. A monoclonal antibody that recognizes an Aβ related peptide, and is produced by a hybridoma deposited under the accession number NITE BP-02998 at the NITE Patent Microorganisms Depositary of the National Institute of | 2022-08-25 |
20220268790 | EVALUATING METHOD FOR PHARMACOLOGICAL ACTIONS OF IMMUNE CHECKPOINT INHIBITORS, CALCULATING METHOD, EVALUATING APPARATUS, CALCULATING APPARATUS, EVALUATING PROGRAM, CALCULATING PROGRAM, RECORDING MEDIUM, EVALUATING SYSTEM, AND TERMINAL APPARATUS - An evaluating method includes an evaluating step of evaluating a pharmacological action of an immune checkpoint inhibitor in a subject to be evaluated, using (i) a concentration value of at least one metabolite among Glu, Arg, Orn, Cit, His, Val, Phe, Tyr, Met, Pro, Asn, Leu, Lys, Thr, Ile, Gln, Ala, Ser, a-ABA, Trp, Gly, AnthA, hAnthA, hIAA, hKyn, hTrp, IAA, ILA, Kyn, KynA, NFKyn, NP, PA, QA, Serot, and XA in blood of the subject to be evaluated, or (ii) a value of a formula calculated using the concentration value and the formula including an explanatory variable to be substituted with the concentration value. | 2022-08-25 |
20220268791 | COMPOSITIONS AND METHODS FOR THE DETECTION OF HOST CELL PROTEINS - Disclosed herein are, inter alia, methods and compositions useful for detecting and/or quantifying host cell proteins during the production of a product, e.g., a recombinant protein, e.g., an antibody. | 2022-08-25 |
20220268792 | COMPOSITIONS AND METHODS FOR THE DETECTION OF HOST CELL PROTEINS - Disclosed herein are, inter alia, methods and compositions useful for detecting and/or quantifying host cell proteins during the production of a product, e.g., a recombinant protein, e.g., an antibody. | 2022-08-25 |
20220268793 | ASSAY SYSTEM INCLUDING ASSAY APPARATUS AND HANDHELD SINGLE USE ASSAY DEVICES FOR USE THEREWITH - Assay systems including assay apparatus and handheld assay devices for use therewith for obtaining diagnostic information of a bodily specimen. Assay devices include a cartridge housing snugly accommodating a specimen slide intended for elevation from an initial lowermost specimen introduction position to a final uppermost specimen examination position in which a bodily specimen is compressed between a cartridge housing top face and a specimen slide. Assay devices preferably include a liquid reagent dispensing arrangement for dispensing liquid reagent on a specimen slide for reacting with a bodily specimen. | 2022-08-25 |
20220268794 | CELL PICKING DEVICE - A cell picking device includes a supporter that supports a rack having a plurality of holes for holding a plurality of pipette tips, a sucker used to suck a sample, a driver that moves the sucker in an up-and-down direction and moves the sucker and the supporter relative to each other in a horizontal direction, and a controller that controls the driver such that, any pipette tip out of the plurality of pipette tips held by the rack is attached to the sucker by movement of the sucker in the up-and-down direction and the sucker is moved to a position outwardly of the rack by movement of the sucker and the supporter relative to each other. | 2022-08-25 |