34th week of 2022 patent applcation highlights part 8 |
Patent application number | Title | Published |
20220265487 | ABSORBENT STRUCTURE FOR ABSORBENT ARTICLES - Absorbent structures for absorbent articles are provided. The absorbent structure includes an absorbent layer with absorbent material supported by a supporting sheet, and a channel that is free of the absorbent material. The channel has a wet integrity of at least 20%. | 2022-08-25 |
20220265488 | ABSORBENT LAMINATE INCLUDING A SPUNLACE NONWOVEN LAYER, ABSORBENT CORES WITH SUCH LAMINATES, AND ABSORBENT ARTICLES WITH SUCH ABSORBENT CORES - Absorbent laminates and folded multi-layer absorbent cores including one or more of the present absorbent laminates The present absorbent laminates comprise an absorbent layer between two laminate layers, at least one of which absorbent laminates including a spunlace nonwoven. Some of the present multi-layer absorbent cores are folded to define a channel running longitudinally along the core to enhance liquid distribution and absorption. | 2022-08-25 |
20220265489 | ABSORBENT ARTICLES HAVING A FOLDED ABSORBENT CORE DEFINING ONE OR MORE CHANNELS - In a particular implementation, an absorbent article includes a chassis having opposing front and rear waist portions and a crotch portion extending longitudinally between the front and rear waist portions. The crotch portion is configured to conform about at least one of a wearer's groin area, perineum, and rear when the chassis is configured in a wearable configuration. The absorbent article also includes an absorbent core extending longitudinally along the crotch portion and including a laminate The laminate is longitudinally folded such that the absorbent core includes a lower layer spanning a portion of a lateral width of the absorbent core. The lower layer includes a first portion and a second portion. The absorbent core also includes a plurality of folded layers of the laminate disposed over the lower layer and configured to define one or more non-overlapping channels. | 2022-08-25 |
20220265490 | Closure Tape Tab with an Inner Tab Portion Having Mechanical Fastening Elements - The present disclosure relates to a closure tape tab | 2022-08-25 |
20220265491 | ONE-TIME USE ONLY COVER FOR MEDICAL APPLIANCE - A waterproof limb cover for preventing liquid ingress to a predefined region of a limb comprising a casing with at least one opening, into which a limb can be inserted. The casing, which is impermeable to the liquid, has at least one sealing closure mechanism to sealingly enclose a predefined region of the limb. The casing further comprises at least one predefined irreversibly rupturable region. Rupture of the irreversibly rupturable region allows removal of the waterproof limb cover from the limb, and prevents undesirable reuse of the cover. | 2022-08-25 |
20220265492 | Patient Transport Apparatus With Controlled Auxiliary Wheel Deployment - A patient transport apparatus transports a patient over a floor surface. The patient transport apparatus comprises a support structure and support wheels coupled to the support structure. An auxiliary wheel is coupled to the support structure to influence motion of the patient transport apparatus over the floor surface to assist users. An actuator is operatively coupled to the auxiliary wheel and operable to move the auxiliary wheel relative to the support structure from a retracted position to a deployed position. A user interface sensor is operatively connected to the actuator and configured to generate signals responsive to the user touching the user interface. A controller is operatively coupled to the user interface sensor and the actuator to operate the actuator in response to detection of signals. | 2022-08-25 |
20220265493 | REMOVABLE WEATHER SHIELD DEVICE FOR MEDICAL STRETCHERS - A weather shield device for a medical stretcher includes a generally square-shaped malleable main body member that is constructed from one or more layers of waterproof fabric. An elongated hollow channel is positioned along the periphery of the main body for receiving and housing a self-supporting frame. The frame and main body are transitioned between a folded position, a fully open position and an arched position for use with a stretcher. A plurality of connectors are disposed along the sides of the main body and function to selectively engage the sides of a medical stretcher. When secured onto the stretcher, the frame forms an arched shape so as to fully cover the stretcher with the waterproof main body, and a pair of semi-rigid struts maintain a set separation distance between the sides of the main body when in the arched position. | 2022-08-25 |
20220265494 | Extension of Patient Support Deck - A patient support apparatus comprises a deck extension assembly having a handle or more handles located on the support frame. The deck extension part is configured to extend and retract relative to the support frame by pulling the handle easily by one hand and with exerting minimum force that is necessary to extend the patient support deck. | 2022-08-25 |
20220265495 | ADJUSTABLE PEDESTAL STRUCTURE OF THE BED - The object of the invention is the adjustable pedestal structure of the bed, by means of which the height and tilt positions of the sleeping platform structure can be adjusted. The pedestal structure consists of the three structural parts supported by the foot structure ( | 2022-08-25 |
20220265496 | MOVABLE MEDICAL BED SYSTEM AND MRI APPARATUS - A movable medical bed system may include a bed body and a power supply apparatus. The power supply apparatus may include an electrical energy receiver and an electrical energy transmitter. The electrical energy receiver is arranged on the bed body. The electrical energy transmitter is configured to be connected to a power source. The bed body is able to move to a working position relative to the electrical energy transmitter. When the bed body is located at the working position, the electrical energy receiver can engage in electrical energy transmission with the electrical energy transmitter without plugging-in. The movable medical bed system helps to make the supply of power more convenient. | 2022-08-25 |
20220265497 | SYSTEMS AND METHODS FOR LIFTING AND POSITIONING A PATIENT - An inflatable device for lifting a patient includes an inflatable body having a top sheet and a bottom sheet attached along opposing side edges and forming at least one cavity there between, and a plurality of connecting members extending outwardly from the opposing side edges of the inflatable device. The inflatable device is configured to be inflated while being lifted by the hoist. | 2022-08-25 |
20220265498 | VEHICLE-TYPE MOBILE INFECTIOUS DISEASE CLINIC - The present disclosure relates to a vehicle-type mobile infectious disease clinic, and more particularly, to a mobile infectious disease clinic, which is a vehicle-type mobile infectious disease clinic, that allows a test subject to be tested by a healthcare provider using an infectious disease test kit while exposure of the body parts is minimized and the healthcare provider and the test subject are isolated in the vehicle-type mobile infectious disease clinic, that performs sterilization of an infectious disease using an ultraviolet C (UV-C) lamp to reduce the time taken for disinfecting the clinic, and that allows the light radiation intensity of the UV-C lamp to be adaptively adjusted according to the body temperature of the test subject. | 2022-08-25 |
20220265499 | Bedding Foundation Having Multiple Lift Actuators For Massage Effect - A bedding foundation has a linear actuator for moving a roller carriage forward and backwards. The roller carriage includes wheels which move along rails supported below a rigid platform having an opening extending through the platform. The roller carriage includes a lifter which raises and lowers a roller independently of the movement of the linear actuator. Regardless of the position of the linear actuator, the roller may be raised or lowered. The roller moves back and forth inside the opening extending through the rigid platform and imparts a massage movement to a mattress above the foundation. | 2022-08-25 |
20220265500 | LATERAL ARM AND TORSO SUPPORT DEVICE - A lateral arm support device configured to support and anteriorly extend the arms of a patient away from the torso during a medical procedure. The lateral arm support device includes spaced apart panels, one forming a superior panel and the other forming an inferior panel, an upper arm support surface extending between the upper sides of the superior and inferior panels, and a lower arm support surface extending between the lower sides of the superior and inferior panels. The panels have shapes that define an anterior cutout extending from the anterior side of the lateral arm support towards the posterior side of the lateral arm support, beneficially allowing increased visualization and access to the lower arm of a patient. The lateral arm support device can be part of a patient positioning system configured to position a patient in a lateral decubitus position. | 2022-08-25 |
20220265501 | ROBOTIC HEAD HOLDING SYSTEM FOR SURGICAL PROCEDURES, AND ASSOCIATED DEVICES AND METHODS - The present technology is directed to robotic systems that support and selectively adjust a position of a patient's head and neck during surgery. The robotic head holding systems may include a patient engagement assembly for supporting a portion of the patient and one or more arm segments connecting the patient engagement assembly to a surgical bed. An actuator can move the patient engagement assembly and/or the one or more arm segments to adjust a position of the patient, and a controller can receive user inputs for automatically controlling operation of the actuator. | 2022-08-25 |
20220265502 | SYSTEMS AND METHODS OF PORTABLE THERAPEUTICS OF EYE DISORDERS - A fully wearable, wireless soft electronic system that offers a portable, highly sensitive tracking of eye movements (vergence) via the combination of skin-conformal sensors and a virtual reality system. Advancement of material processing and printing technologies based on aerosol jet printing enables reliable manufacturing of skin-like sensors, while the flexible hybrid circuit based on elastomer and chip integration allows comfortable integration with a user's head. Analytical and computational study of a data classification algorithm provides a highly accurate tool for real-time detection and classification of ocular motions. In vivo demonstration with 14 human subjects captures the potential of the wearable electronics as a portable therapy system, whose minimized form factor facilitates seamless interplay with traditional wearable hardware. | 2022-08-25 |
20220265506 | SYSTEM, METHOD AND APPARATUS FOR PAIN CONTROL AND HEALING - A device for treating a user includes a housing having apertures. The housing has application areas including a convex top surface, a concave bottom surface, a convex rear surface, convex side surfaces and rounded protrusions extending away from the housing. A vibrational source is located in the housing to produce vibration at the application areas. A switch is in operative communication with the vibrational source to control operation of the vibrational source. | 2022-08-25 |
20220265507 | VIBRATING GARMENT ASSEMBLY - A garment assembly includes a sleeve member having outer and inner surfaces, a first vibration assembly associated with the sleeve member, and a control module associated with the sleeve member. The first vibration assembly includes a plurality of vibration motors that are arranged in a circle about a center point. An angular distance between each vibration motor of the plurality of vibration motors is approximately the same. The control module includes a battery, and the first vibration assembly is in electrical communication with the control module. | 2022-08-25 |
20220265508 | HEAD UP CPR DEVICE WITH INTEGRATED VENTILATOR - A head up CPR system may include a base and an upper support coupled with the base and configured to elevate a patient's upper body. The system may include a chest compression device that is coupleable with one or both of the base and the upper support and a positive pressure ventilation system that is coupleable with the base. | 2022-08-25 |
20220265509 | ACTIVE COMPRESSION DECOMPRESSION AND UPPER BODY ELEVATION SYSTEM - An elevation device used in the performance of cardiopulmonary resuscitation (CPR) and after resuscitation includes a base and an upper support operably coupled to the base. The upper support is configured to elevate an individual's upper back, shoulders and head. The elevation device also includes a chest compression device coupled with the base. The chest compression device is configured to compress the chest and to actively decompress the chest. | 2022-08-25 |
20220265510 | CARDIOPULMONARY RESUSCITATION DEVICE, CONTROL, METHOD AND COMPUTER PROGRAM - According to an aspect, there is provided a cardiopulmonary resuscitation, CPR, device ( | 2022-08-25 |
20220265511 | Acupuncture device and method of using magnetic fields to stimulate acupuncture needles, and magnetic coil configurations - Devices and methods for generating and applying stimulated acupuncture needles to one or more acupuncture points on a body of an individual suffering from one or more ailments using magnetic fields. The acupuncture device is configured for generating magnetic fields to stimulate acupuncture without using human manual manipulation. The acupuncture device may comprise a control unit and one or more acupuncture needle stimulation units. Each one or more acupuncture needle stimulation unit is functionally connected to the control unit by a cable or lead. The control unit may include a variable frequency generator configured to deliver various power levels, direct voltages, or a combination of various power levels and direct voltages to the acupuncture needle stimulation units, alone or in combination with other stimuli. Special magnetic coil configurations may be used to boost coil efficiently and reduce the required energy to generate comparable magnetic fields. | 2022-08-25 |
20220265512 | Chakra Aligning Wellness Wear - The present invention provides a wearable wellness device that comprises a plurality of sections. The sections include a bracket, side members, a first line member, a second line member; and a plurality of stones attached to the bracket. The plurality of sections are connected by the first line member and the second line member. Some sections can be eliminated in the wearable wellness of the present invention the arrangement of the sections can be altered. | 2022-08-25 |
20220265513 | WIRELESS MEDICATION BLISTER PACK SYSTEM AND BLISTER PACK ATTACHMENT - The present disclosure relates to wireless medication blister pack assembly and to a blister pack attachment to be secured to a blister pack assembly. The attachment an electronic card housing for receiving an electronic card which includes electronic components such as card connectors, and a locking system which is configurable between a locked configuration and a releasing configuration. In the locked configuration, the blister pack assembly and the electronic card are connected, with sheet connectors provided on the blister pack assembly and the card connectors being in electronic communication. Such electronic communication allows the electronic components to detect whether a given blister has been detached from the blister pack assembly. In the releasing configuration, the electronic card and the blister pack assembly can be removed from the blister pack attachment, so as to allow the electronic card to be reused with a replacement blister pack assembly. | 2022-08-25 |
20220265514 | TEMPERATURE CONTROLLED PRODUCT SHIPPER WITH A DUAL PHASE CHANGE MATERIAL LIQUID SUSPENSION - A temperature-controlled shipper for shipping diagnostic blood samples is disclosed. The shipper must remain at a temperature between 6° C. and 37° C. for up to 24 hours while in transit. The shipper includes identical mating PCM blow-molded bottles which enclose and protect diagnostic blood sample vials. Identical mating clamshell insulating containers further enclose and protect the PCM bottles. Both the bottles and clamshell containers can be re-used. A dual PCM liquid suspension is utilized in the PCM bottles and is preconditioned and stored at a single temperature. | 2022-08-25 |
20220265515 | PACKAGING FOR PHARMACEUTICAL PRODUCTS - In a packaging for pharmaceutical products, comprising a primary packaging for receiving a dose or several doses of a pharmaceutical product, and a secondary packaging designed as a cardboard box in which the primary packaging is received, the primary packaging is arranged in an insulation shell having a latent heat storage material. | 2022-08-25 |
20220265516 | DOSING AND ADMINISTRATION SYSTEM FOR DRUG COMBINATIONS - The present invention provides a cartridge for the preparation of a liquid pharmaceutical or nutraceutical formulation, the cartridge being adapted for insertion into a mixing vessel and for dispensing at least three flowable pharmaceutical or nutraceutical compositions into said mixing vessel, the cartridge comprising a container portion, a cover portion and an opening means, or more specifically an opening means of the container portion, for opening the cartridge, preferably after its insertion into the mixing vessel, wherein the container portion comprises a container wall and a container base, the container wall and the container base defining an inner lumen and an opening of the container portion, the opening being positioned opposite to the container base, and a segmenting structure located in the inner lumen of the container portion and being physically connected to the container wall and/or to the container base such as to divide the inner lumen of the container portion into at least three segments containing the at least three flowable pharmaceutical or nutraceutical compositions. | 2022-08-25 |
20220265517 | MACHINE AND METHOD FOR FILLING CAPSULES - A filling machine ( | 2022-08-25 |
20220265518 | DENTAL HYDRAULIC CEMENT COMPRISING ULTRAFINE CALCIUM SILICATE PARTICLES HAVING FAST HARDENING AND SUITABLE MECHANICAL PROPERTIES - A dental restoration material made from a dental hydraulic cement that includes ultrafine calcium silicate (UCS) particles, in the presence of a limited amount of water, so that the hydraulic cement fast hardens while providing a material having suitable mechanical properties for dental restoration, and especially a high compressive strength. | 2022-08-25 |
20220265519 | PREPARATION AND FULLY COMPOUNDED STOCK FOR USE IN MEDICAL OR DENTAL APPLICATIONS, MEDICAL OR DENTAL PRODUCT AND USE AND PREPARATION THEREOF - According to the invention, a preparation is described which contains at least one calcium compound selected from the group consisting of calcium phosphates, calcium fluorides and calcium fluorophosphates and hydroxyl derivatives and carbonate derivatives of these calcium salts, calcium hydroxides and calcium oxides precipitated using at least one protein component selected from proteins and protein hydrolysates, and at least one crosslinking agent for the protein component and/or non-set cement. | 2022-08-25 |
20220265520 | AQUEOUS LIQUID COSMETIC AND PEN-SHAPED COSMETIC PRODUCT - An aqueous liquid cosmetic contains a pigment, a dispersant, and an inorganic salt, and the cosmetic has a viscosity of 1 to 50 mPas at 25° C. The pigment contains at least one selected from the group consisting of Prussian blue and lakes of natural colorants, and the inorganic salt contains at least one selected from the group consisting of a chloride, a sulfate, a nitrate, a carbonate, and a phosphate. | 2022-08-25 |
20220265521 | MOISTURIZING FILM COSMETIC MATERIAL - There is provided a cosmetic which can moisturize the skin and exhibit a beautifying effect in low humidity environments while reducing sticky uncomfortable feelings in high humidity environments or sweaty states. | 2022-08-25 |
20220265522 | Lotion Pellet and Method of Manufacture - A method of manufacturing a lotion pellet, and a lotion pellet, is disclosed. The method comprises the steps of mixing a combination of coconut oil, cocoa butter, shea butter and beeswax, over heat, for a period of time to form an integrated mixture of the combination, providing a mold having a mold cavity, poring an amount of the integrated mixture into the mold cavity, allowing the poured amount of the integrated mixture to settle in the mold cavity for a period of time, chilling the integrated mixture in the mold for a period of time, to form the lotion pellet, and removing the lotion pellet from the mold cavity. | 2022-08-25 |
20220265523 | Peroxymonosulfate Whitening Strips - The present disclosure provides a tooth whitening strip comprising a hydratable adhesive film comprising an inorganic salt of peroxymonosulfate, preferably an alkali metal salt or alkaline earth metal salt, or mixtures thereof, and methods of using the same. | 2022-08-25 |
20220265524 | HYDROPHILIC INORGANIC POWDER AND COSMETIC PREPARATION CONTAINING THE SAME - A hydrophilic inorganic powder having excellent self-dispersibility in water or an aqueous solvent, which could not be conventionally achieved, and a cosmetic preparation containing the hydrophilic inorganic powder are provided by combining a hydrophilic surfactant and lipophilic surfactant. There is provided the hydrophilic inorganic powder comprising an inorganic powder as a base material; a hydrophobic-coat that covers the surface of the inorganic powder; and a hydrophilic-coat that covers the hydrophobic-coat, wherein ingredients of the hydrophilic-coat comprises both a hydrophilic surfactant and a lipophilic surfactant, and each of the hydrophilic surfactant and the lipophilic surfactant has a branched alkyl moiety in their molecules, wherein the hydrophilic inorganic powder has self-dispersibility in water or an aqueous solvent. | 2022-08-25 |
20220265525 | PARTICLES CONTAINING STARCH, METHOD FOR PRODUCING SAME, AND COSMETIC PREPARATION - Particles having excellent touch properties are achieved with a water-soluble material having excellent biodegradability. Particles according to the present invention contain a starch having an amylopectin content of 90% by weight or more. The average particle diameter d | 2022-08-25 |
20220265526 | OIL-DISPERSED COMPOSITION AND COSMETICS FOR LIP CARE USING THE SAME - Disclosed are an oil-dispersed composition and a cosmetic for lip care manufactured using the same. The oil-dispersed composition includes a water-soluble raw material, an ester oil including a glyceryl group and/or an isostearyl group, a paste, and a thickener, wherein the paste and thickener are included in an amount of greater than or equal to about 30 wt % based on the total amount of the oil-dispersed composition. | 2022-08-25 |
20220265527 | MICROENCAPSULATED PROBIOTIC AND COMPOSITIONS CONTAINING THE SAME - Microencapsulated freeze-dried probiotics along with methods of making and using them are disclosed. More specifically, the present disclosure relates to a probiotic microcapsule comprising a probiotic stasis pod, a nutrient rich carrier and a protective barrier layer. The microencapsulated probiotics as described are useful for inclusion in consumer and skincare products. | 2022-08-25 |
20220265528 | WATER-SOLUBLE REFILL DOSE ARTICLE ENCLOSING A CONCENTRATED CLEANSER COMPOSITION AND KITS HAVING SAME - Water-soluble refill dose articles for forming a cleanser have a water-soluble film defining a first compartment enclosing a first composition and a second compartment enclosing a second composition, which are individual separate articles or are part of an integral article. The first composition has a rheology modifier, a first surfactant, 10% or less by weight water, 20% or less by weight glycol, and the first surfactant does not activate the rheology modifier. The second compartment has an alkaline substance that when mixed with the first composition and water activates the rheology modifier to increase the viscosity of a resulting cleanser and 10% or less by weight water. When the article is diluted in water at a 1:1 to 1:20 ratio, it produces a cleanser having a viscosity within a range of 2000 cps to 50,000 cps. | 2022-08-25 |
20220265529 | Making An Oral Care Article Of Manufacture - A process, for example a continuous process, for making an oral care article of manufacture containing a fibrous composition, for example a composite structure, and more particularly to a process for making an oral care article of manufacture containing a fibrous composition, such as a soluble fibrous composition, containing soluble filaments is provided. | 2022-08-25 |
20220265530 | ORAL CARE COMPOSITIONS COMPRISING PEROXIDE AND POLYMER - Oral care compositions including peroxide, amphiphilic polymer, and optionally water. Dentifrice compositions including peroxide, amphiphilic polymer, and optionally water. The present invention also relates to dentifrice compositions comprising peroxide with an unexpectedly high viscosity through the addition of amphiphilic polymer and/or alkyl alcohol. Methods of use of the disclosed compositions to whiten teeth. | 2022-08-25 |
20220265531 | ORAL CARE COMPOSITIONS COMPRISING PEROXIDE AND COMPATIBLE ABRASIVE - Oral care compositions including peroxide and abrasive. Dentifrice compositions including peroxide and abrasive. Oral care compositions including peroxide and calcium pyrophosphate. Dentifrice compositions including peroxide and calcium pyrophosphate. Dentifrice compositions including peroxide and calcium pyrophosphate with a gamma phase to beta phase ratio of at least about 0.8. Dentifrice composition including peroxide and calcium pyrophosphate with a gamma phase to beta phase ratio of at least about 1. Methods of use of the disclosed compositions to whiten teeth. | 2022-08-25 |
20220265532 | ORAL CARE COMPOSITIONS COMPRISING PEROXIDE AND ALUMINA - Oral care compositions including peroxide, alumina, and optionally water. Dentifrice compositions including peroxide, alumina, and optionally water. Dentifrice compositions including peroxide, calcined alumina, and optionally water. Dentifrice compositions including peroxide, calcined alumina, uncalcined alumina, and optionally water. Methods of use to whiten teeth using one or more of the disclosed compositions. | 2022-08-25 |
20220265533 | HYDRATING ORAL CARE COMPOSITIONS COMPRISING PEROXIDE - Hydrating oral care compositions including peroxide and water. Hydrating dentifrice compositions including peroxide and water. Hydrating oral care compositions including peroxide and water that can release at least about 1% of the peroxide within 120 seconds. Hydrating oral care compositions including peroxide and water that can release at least about 15% of the peroxide within 15 minutes. | 2022-08-25 |
20220265534 | LIQUID COSMETIC COMPOSITION - Provided is a liquid cosmetic composition which provides easily a clear and brilliant coating film without causing flaky pigments to be overlapped on each other when the liquid cosmetic composition containing a small amount of brilliant flaky pigments is filled in an applicator having a coating part composed of a brush to be coated on a surface such as a skin. The liquid cosmetic composition of the present invention is characterized in containing at least 0.01 to 10 mass % of a flaky pigment coated on a surface with a compound selected from the following A group, 0.05 to 5 mass % of layered clay mineral particles, 1 to 20 mass % of an acrylic copolymer in terms of a solid content and water and being filled in an applicator provided with a coating part having a brush: | 2022-08-25 |
20220265535 | Core Shell Silica Particles and Uses Thereof As an Anti-Bacterial Agent - This invention provides core shell silica particles, wherein each core shell silica particle comprises a silica core, and a surface of the silica core etched with group I metal silicate. These core shell silica particles have high surface charge density and anti-bacterial activity. Also provided are compositions comprising core shell silica particles, process of making the core shell silica particles and methods of reducing or inhibiting bacterial activity by administering the core shell silica particles or compositions thereof. | 2022-08-25 |
20220265536 | Depilatory Compositions Comprising Aminoalkylpropanol - The present invention is directed to depilatory compositions comprising a depilatory active, alkali metal hydroxide and an aminoalkylpropanol. The compositions have a pH in the range of from 10 to 12.5. The depilatory active preferably contains a thiol group, the alkali metal hydroxide preferably comprises potassium hydroxide and the aminoalkylpropanol preferably comprises aminomethylpropanol. The composition is preferably a gel, mousse, foam, cream, lotion or peelable film, especially a translucent or transparent gel. The depilatory compositions provide effective hair removal yet are well tolerated by the skin and allow for acceptable application times of the composition. The present invention further provides a depilatory composition comprising urea, a carbomer, and a gum; these compositions may or may not comprise aminoalkylpropanol. | 2022-08-25 |
20220265537 | COMPOSITION FOR DYEING KERATIN FIBRES AND USE THEREOF - A dye kit comprising: (A) a dyeing composition (A) and (B) a pyrazolone composition (B) comprising a retarding combination of pyrazolone compound and a reducer. | 2022-08-25 |
20220265538 | PEPTIDE HAVING HAIR GROWTH PROMOTING ACTIVITY AND USE THEREOF - Provided are a peptide having an activity of promoting hair generation and use thereof. In particular, provided are a peptide consisting of an amino acid sequence of SEQ ID NO: 1, a composition including the peptide for improving hair loss or promoting hair generation, and a pharmaceutical composition including the peptide for preventing or treating hair loss. | 2022-08-25 |
20220265539 | HAIR TREATMENT COMPOSITION, METHOD FOR OBTAINING SAME, USE OF THE COMPOSITION AND HAIR TREATMENT METHOD - A composition for hair treatments, as well as a process for obtaining the same, comprising a molecule of glyoxyloyl protein, more specifically, hydrolyzed wheat protein and sericin. The composition promotes hair straightening, without damaging the hair fibers, quickly and safely, and is in the fields of chemistry and cosmetics. | 2022-08-25 |
20220265540 | COMPOSITION COMPRISING ALKYLCELLULOSE, INCOMPATIBLE HYDROCARBON AND SILICONE OILS AND METHOD EMPLOYING IT - The present invention is relating to a cosmetic composition comprising:
| 2022-08-25 |
20220265541 | HAIR CARE COMPOSITION - A hair care composition is disclosed comprising an anti-dandruff agent selected from piroctone olamine, selenium sulfide and mixtures thereof and a copolymer comprising acrylamidopropyltrimonium chloride, wherein the weight ratio of the amount of the copolymer to the amount of the anti-dandruff agent is in the range of from 1:5 to 1:1. | 2022-08-25 |
20220265542 | PETROLATUM ALTERNATIVE FROM RENEWABLE SOURCES - The present application provides a substitute for petrolatum that does not contain any petroleum-based components. The petrolatum substitute gel composition comprises at least one plant-derived paraffinic wax, at least one plant-derived paraffinic oil, and at least one natural wax. Optionally, the at least one natural wax is beeswax, berry wax (e.g., bay berry wax), candelilla wax, green tea wax, carnauba wax, myrica fruit wax, rice bran wax, a hydrogenated seed oil wax, ouricury wax, shellac wax or tallow tree wax, and the at least one plant-derived paraffinic wax and the at least one plant-derived paraffinic oil are manufactured from a method that comprises a Kolbe-electrolysis process. Also provided is a method for manufacturing the gel composition. | 2022-08-25 |
20220265543 | COSMETIC COMPOSITIONS AND USES THEREOF - The invention features cosmetic compositions comprising Swertia chirata extract and hydrolyzed Ceratonia siliqua seed extract formulated for topical administration and their related uses, e.g., for reducing skin aging or wrinkles. | 2022-08-25 |
20220265544 | TEETH CLEANING ANIMAL CHEW - A composition of matter for dental plaque removal comprising at least one of a strain of the bacteria | 2022-08-25 |
20220265545 | COMPOSITION FOR IMPROVING SKIN CONDITION - The present application relates to a composition for improving skin condition, comprising | 2022-08-25 |
20220265546 | TOPICAL COMPOSITIONS CONTAINING ROFECOXIB AND METHODS OF MAKING AND USING THE SAME - The present disclosure provides topical compositions of rofecoxib and methods of making said compositions. The present disclosure also provides methods of using topical compositions of rofecoxib to treat inflammation. | 2022-08-25 |
20220265547 | PARENTERAL CARBAMAZEPINE FORMULATION - The present invention is directed to a carbamazepine-cyclodextrin inclusion complex useful for the parenteral administration of carbamazepine. The carbamazepine-cyclodextrin inclusion complex is prepared by the admixture of a modified cyclodextrin and carbamazepine in a physiologically acceptable fluid. Modified cyclodextrins include 2-hydroxypropyl-beta-cyclodextrin and sulfoalkyl cyclodextrins. More particularly, the sulfoalkyl cyclodextrins are those described and disclosed in U.S. Pat. Nos. 5,134,127 and 5,376,645. A physiologically acceptable fluid includes sterile isotonic water, Ringer's lactate, D5W (5% dextrose in water), physiological saline, and similar fluids suitable for parenteral administration. | 2022-08-25 |
20220265548 | ANIMAL TREAT COMPOSITION FOR DELIVERY OF ORAL MEDICATION - An animal treat composition for the oral administration of a medication to an animal is disclosed. The animal treat composition comprises an adhesive portion core and an outer portion. The adhesive portion adheres to oral medication inserted into the adhesive core of the treat for administration of the medication to an animal. | 2022-08-25 |
20220265549 | PHARMACEUTICAL COMPOSITION COMPRISING ENSIFENTRINE - The present invention relates to a dry powder pharmaceutical composition suitable for administration by inhalation comprising: (i) ensifentrine particles; (ii) coarse lactose particles having a Dv50 of from 40 μm to 80 μm; and (iii) fine lactose particles having a Dv50 of from 5 μm to 10 μm, wherein: the fine lactose particles are present in an amount of from 0.1 wt % to 6.0 wt % relative to the total weight to the dry powder pharmaceutical composition. Also provided is a dry powder inhaler comprising the dry powder pharmaceutical composition and medical use of the dry powder pharmaceutical composition. | 2022-08-25 |
20220265550 | APPLICATOR HEAD WITH DOSING AID - There is provided an applicator head ( | 2022-08-25 |
20220265551 | FORMULATIONS OF GLUCAGON-LIKE-PEPTIDE-2 (GLP-2) ANALOGUES - Liquid formulations of GLP-2 analogues that make them suitable for long term storage as liquids and/or that makes them especially suitable for delivery by a drug delivery device are described. Solid compositions comprising acetate salts of glucagon-like peptide 2 (GLP-2) analogues useful for making the liquid formulations are also described. The development of these liquid formulations is based on the finding that acetate present in the formulation that originates from the GLP-2 analogues has an effect on the viscosity of the formulation, that during long term storage at 2-8° C. of GLP-2 analogues, the concentration dependence for covalent oligomer formation is inversely dependent on increasing concentration of the GLP-2 analogue, and that GLP-2 analogues used in the formulations are not compatible with phosphate buffer commonly used in the prior art to reconstituted powdered or lyophilized GLP-2 compositions. | 2022-08-25 |
20220265552 | ESLICARBAZEPINE SUSPENSION - The present invention relates to oral ready to use liquid pharmaceutical compositions of eslicarbazepine. It also relates to the processes for the preparation of said liquid compositions. The present invention provides liquid compositions of eslicarbazepine with desired technical attributes such as release profile, viscosity, pH, stability, and acceptable organoleptic properties. The prepared compositions are useful in patients having difficulties in swallowing tablets and provide the physician with providing a more convenient and less cumbersome posology. The suspension compositions as per present invention are useful for the treatment of seizures, partial-onset seizures, epilepsy, neuropathic pain, migraine, fibromyalgia, trigeminal neuralgia, bipolar disorders, attention disorders, anxiety disorders, affective disorders, schizoaffective disorders, sensorimotor disorders, and vestibular disorders. | 2022-08-25 |
20220265553 | EMOLLIENT EMULSION - A process of making a composition of matter with emollient properties. The composition takes the physical form of an oil base homogenized into water, making it suitable for dispensation in large quantities with a spray bottle or a continuous flow. Preparation begins with refinement of MCT coconut oil to remove lauric acid. The coconut oil is mixed with arnica oil, castor oil, and CBD oil to form the oil base. Ideal proportions for the oil base are approximately 1:4:1:4 arnica:castor:CBD:coconut. The oil base is then heated and homogenized into alkaline water by blending. Ideal parameters are approximately 11.5 pH water, a ratio of approximately 7:93 oil:water, and ten minutes of blending. Suitable variations on the ideal parameters are disclosed below. | 2022-08-25 |
20220265554 | THERMOGELLING NANOEMULSIONS FOR PHARMACEUTICAL MANUFACTURING - Compositions contain nanoparticles containing nanocrystals of hydrophobic therapeutic, diagnostic, prophylactic agents, or a combination thereof, encapsulated in thermogelling polymers, such as methyl cellulose. Because of the templating of the compositions on a thermogelling nanoemulsion system, the compositions can be formed with precise control of the sizes of the nanoparticles as well as the high loadings of these hydrophobic therapeutic, diagnostic, prophylactic agents, or a combination thereof. Also described are methods of making and using the compositions. | 2022-08-25 |
20220265555 | CANNABINOID CONTAINING TARGETING LIPOSOMES - Described herein are liposomes containing modified targeting peptides. Liposomes preferably comprise a lipid-based bilayer and at least one cannabinoid. Also provided herein are methods for making the liposomes, and methods for treatment of diseases of the CNS using the liposomes. | 2022-08-25 |
20220265556 | LIPOSOMAL DOXORUBICIN FORMULATION, METHOD FOR PRODUCING A LIPOSOMAL DOXORUBICIN FORMULATION AND USE OF A LIPOSOMAL DOXORUBICIN FORMULATION AS A MEDICAMENT - The present invention relates to a liposomal doxorubicin formulation, a method for producing a liposomal doxorubicin formulation and a liposomal doxorubicin formulation for use as a medicament, in particular for use in the treatment of cancer, uterine leiomyosarcoma and adnexal skin cancer. | 2022-08-25 |
20220265557 | CENTANAFADINE PHARMACEUTICAL FORMULATIONS, AND METHODS OF MAKING AND USING SAME - Pharmaceutical formulation comprising centanafadine or a pharmaceutically acceptable salt thereof and an excipient, and related methods of manufacture and use, are disclosed. | 2022-08-25 |
20220265558 | METHODS AND ASSEMBLIES FOR PREPARING AND DISPENSING LYOSPHERES OF PHARMACEUTICAL COMPOSITIONS - Disclosed herein are methods for preparing and/or dispensing lyospheres of pharmaceutical compositions of biologics (e.g., vaccines, therapeutic proteins such as monoclonal antibodies) or small molecules (e.g., chemical compounds). Also described are assemblies and systems for preparing and/or dispensing the lyospheres. | 2022-08-25 |
20220265559 | DELAYED RELEASE DEFERIPRONE TABLETS AND METHODS OF USING THE SAME - The invention is directed to pharmaceutical compositions such as tablets that exhibit delayed release properties when administered as either whole or half tablets. The invention is also directed to delayed release tablets comprising deferiprone for oral administration, for which twice daily administration is bioequivalent to the same daily dose of an immediate release tablet administered thrice daily. The invention is also directed to methods of making and using the same. | 2022-08-25 |
20220265560 | CAPSULE DEVICE HAVING IMPROVED SELF-RIGHTING ABILITY - A capsule device suitable for insertion into a lumen of a patient, the lumen having a lumen wall, wherein the capsule device ( | 2022-08-25 |
20220265561 | SOFT GELATIN CAPSULES CONTAINING A MIXTURE OF ANALGESICS AND DECONGESTANTS, EXPECTORANTS, ANTITUSSIVES AND/OR ANTIHISTAMINES - Clear bioavailable liquid softgel fill compositions comprising a) at least one analgesic and one or more of decongestants, expectorants, antitussives and/or antihistamines; b) a matrix comprising a pharmaceutically acceptable poly(alkylene glycol) and a pharmaceutically acceptable alkylene glycol; c) a solubilizing agent comprising a pharmaceutically acceptable polymeric solubilizing agent and water are disclosed. Also disclosed are methods for the preparation of such clear fill compositions, and softgel capsules containing the clear bioavailable liquid fill composition. | 2022-08-25 |
20220265562 | MICROSPHERE FORMULATIONS COMPRISING LURASIDONE AND METHODS FOR MAKING AND USING THE SAME - Extended-release microsphere formulations comprising lurasidone are provided. In one aspect, the microsphere formulations are characterized in that the lurasidone is released in vivo in humans over a period of about 30 days. Methods for making and using the formulations are also provided. | 2022-08-25 |
20220265563 | METHODS OF DELIVERING A NEUROPROTECTIVE POLYPEPTIDE TO THE CENTRAL NERVOUS SYSTEM - The present disclosure provides a method for delivering a neuroprotective polypeptide to at least a portion of a central nervous system (CNS) of a subject. The method includes administering to the systemic blood circulation of the subject a therapeutically effective amount of a neuroprotective polypeptide by a controlled-release formulation or a device providing a sustained release of the neuroprotective polypeptide including at least one neuroprotective polypeptide selected from the group consisting of GLP-1, exendin-4, or a therapeutically effective GLP-1 or exendin-4 analogue; the neuroprotective polypeptide binds to and activates a receptor that binds at least one of GLP-1, exendin-4, or a combination thereof; and the controlled-release neuroprotective formulation or the sustained release of the neuroprotective polypeptide enhances the delivery of the neuroprotective polypeptide across a blood-brain barrier (BBB) of the subject to at least a portion of the CNS relative to a rapid release formulation of the neuroprotective polypeptide. Also disclosed is a method of treating a subject with a CNS-related disease or reducing at least one symptom of a CNS-related disease in a subject in need thereof. | 2022-08-25 |
20220265564 | CAPSID THERAPY - A lipid capsid comprising at least one S type protein for attachment to the ACE2 receptor of a cancer cell is provided. The lipid capsid encloses an inner package, comprising histone or a histone eviction compound. The S type protein of the lipid capsid attaches to the ACE2 receptor of a targeted cancer cell, enabling the outer lipid envelope of the capsid to be absorbed through the cell wall of the targeted cell, after which the inner package of the lipid capsid is delivered to the cancer cell. In some embodiments, the histone is selected from the H2AX histone, the H3K27 histone or the H3K9 histone, each histone having a different mechanism of action to disable the cancer cell or repair the DNA of the cancer cell. In another embodiment, the inner package contains a histone eviction compound for evicting histone from the cancer cell. | 2022-08-25 |
20220265565 | NANOTECHNOLOGY-BASED DELIVERY SYSTEM OF BERGAMOT ESSENTIAL OIL, METHOD OF PREPARATION OF THE SYSTEM AND USES THEREOF - The present invention concerns a nanotechnology-based delivery system of bergamot essential oil (BEO) that are α-tocopheryl stearate-Solid Lipid Nanostructures (α-TFS-SLNs) loaded with bergamot essential oil without psoralens (BEO-BF). The present invention concerns also a method of preparation and uses of said α-tocopheryl stearate-Solid Lipid Nanostructures (α-TFS-SLNs) loaded with bergamot essential oil (BEO-BF). | 2022-08-25 |
20220265566 | ATOVAQUONE NANOPARTICULATE COMPOSITIONS - A nanoparticle ATQ composition is provided which has good stability and bioavailability. Compositions and methods of using the nanoparticle ATQ composition in treating parasitic and other infections is described. | 2022-08-25 |
20220265567 | METHOD FOR TREATING OSTEOARTHRITIS - Disclosed is a method for treating osteoarthritis comprising a step of administering a patch to a patient. The patch comprises a backing layer and an adhesive layer laminated on the backing layer, the adhesive layer comprises an adhesive base, diclofenac sodium, dimethyl sulfoxide, and an organic acid, and a content of the organic acid is 6 mass % to 8 mass % with respect to a total mass of the adhesive layer. The patch is applied to an affected part once a day, and a dose of diclofenac sodium per administration is 70 mg to 150 mg. | 2022-08-25 |
20220265568 | PROCESS FOR PREPARING PRESSURE SENSITIVE ADHESIVE COMPOUNDS FOR USE IN A TRANSDERMAL THERAPEUTIC SYSTEM - The invention relates to a process for preparing an active-principle-containing adhesive formulation for use in a transdermal therapeutic system, comprising the following steps: a) providing an adhesive formulation containing a carboxylic acid ester-based solvent and a self-adhesive polymer matrix containing monomers of the compounds on which the polymer matrix is based, b) removing the carboxylic acid ester-based solvent and the monomers from the adhesive formulation, c) re-dissolving the compound obtained in step b) in an organic solvent that does not contain any ester groups, and adding a pharmacologically active principle having at least one hydroxyl group, carboxyl group, amino group and/or ester group so that the active-principle-containing adhesive formulation is obtained. The invention also relates to a transdermal therapeutic system containing the active-principle-containing adhesive formulation. The invention further relates to the use of said transdermal therapeutic system and to a kit containing the transdermal therapeutic system. | 2022-08-25 |
20220265569 | PERMEANT DELIVERY PATCH VIA A FORMED PATHWAY - Thin solid tablet compositions containing an active permeant can be used in methods for administering the permeant to a subject. The thin solid tablet can be incorporated into a patch. The patch can be used to administer the permeant, such as a drug and an excipient, to the subject by transdermal microporation. | 2022-08-25 |
20220265570 | CANNABINOIDS AND USES THEREOF - The present invention provides a pharmaceutical composition including a combination of at least two cannabinoids, and methods of using same, such as for treating a NOTCH 1-related disease. | 2022-08-25 |
20220265571 | COMPOSITION OF CANNABIDIOL FOR USE IN THE TREATMENT AND PREVENTION OF BRONCHIOLITIS OBLITERANS - The present invention is directed to a pharmaceutical composition comprising Cannabidiol and a method of use thereof, i.e., for treating or preventing bronchiolitis obliterans in a subject. | 2022-08-25 |
20220265572 | REMITTIVE EFFECTS OF TAPINAROF IN THE TREATMENT OF PLAQUE PSORIASIS, ATOPIC DERMATITIS, OR RADIATION DERMATITIS - Embodiments described herein are directed to methods for treating moderate to severe plaque psoriasis, atopic dermatitis, or radiation dermatitis in a subject comprising administering about 1.0% tapinarof in a topical composition to the affected areas of the subject once a day for an initial period of time until the plaque psoriasis, atopic dermatitis, or radiation dermatitis is clear at which time the administration is stopped, and reassessing the subject from about 3 months to about 12 months after administration is stopped to determine if further treatment is required. Also described is the remittive effect observed after once daily administration of 1% tapinarof cream. | 2022-08-25 |
20220265573 | CANNABIDIOL-TYPE CANNABINOID COMPOUND - The present invention relates to a cannabidiol (CBD) type cannabinoid compound for use as a medicament. The CBD-type cannabinoid, 6-hydroxy cannabidivarin (6-OH CBDV), is a metabolite of cannabidivarin (CBDV). The cannabinoid can be produced by synthetic means and a method for the production of 6-OH CBDV is described herein. In addition, disclosed herein are data which demonstrate the efficacy of 6-OH CBDV in a model of disease. | 2022-08-25 |
20220265574 | METHODS OF USING CANNABIDIOL AND A STEROID - The invention provides methods for preventing, ameliorating and treating inflammatory diseases with a reduced dose of a steroid by providing a combined cannabidiol (CBD) and steroid therapy. | 2022-08-25 |
20220265575 | NON-STAINING CURCUMINOID COMPOSITION - The invention describes a non-staining composition comprising high content of curcuminoids in granular form, which is substantially free of excipients and is comprised of at least about 94% of curcuminoids. The non-staining composition may be comprised of 0 to 5% by weight of excipients, which are used as processing aids. The non-staining curcuminoid composition does not cause staining and dusting of the equipment and the contact surfaces, while formulating into finished dosage forms. The invention also relates to solvent-free process for preparation of non-staining granular composition; wherein the curcuminoids may be subjected to granulation process at specific temperature conditions. The granular composition is free flowing and retains original yellowish orange colour of the curcuminoids along with its crystalline nature. The solvent-free process for non-staining granular curcuminoid composition is simple, economical and environment friendly, thus making it industrially useful and applicable for formulating finished dosage forms. | 2022-08-25 |
20220265576 | PHOSPHOLIPASE-A2 INHIBITORS FOR THE PREVENTION OF CANCER METASTASIS - A compound of formula (I) | 2022-08-25 |
20220265577 | PROCESS FOR THE PREPARATION OF ANTHRAQUINONE TOPICAL FORMULATION - The present invention relates to the process for the preparation of topical formulations of anthraquinone compound. The present invention specifically relates to the process for the preparation of topical formulations of Rhein or Diacerein in the form of ointment, cream, gel and transferosomal gel. The present invention more specifically relates to the process for the preparation of topical formulations of Rhein or Diacerein in the form of ointment, cream, gel comprising the steps of heating, adding, stirring, dissolving and mixing. The present invention also relates to the process for the preparation of topical formulations of Rhein or Diacerein in the form of transferosomal gel comprising the steps of thin film formation, hydration of thin film and transferosomal gel formation. The present invention also relates to the process for the preparation of topical formulations of Rhein or Diacerein in the form of transferosomal gel comprising the steps of dissolving, adding and mixing. | 2022-08-25 |
20220265578 | POLYMORPHIC AND AMORPHOUS FORMS OF (R)-2-HYDROXY-2-METHYL-4-(2,4,5-TRIMETHYL-3,6-DIOXOCYCLOHEXA-1,4-DIENYL)B- UTANAMIDE - Disclosed herein are polymorphic and amorphous forms of anhydrate, hydrate, and solvates of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide and methods of using such compositions for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging. Further disclosed are methods of making such polymorphic and amorphous forms. | 2022-08-25 |
20220265579 | COMPOSITION FOR PREVENTING OR TREATING CARDIO-CEREBROVASCULAR DISEASE COMPRISING AUTOPHAGY ACTIVATOR AS ACTIVE INGREDIENT - The present invention relates to a pharmaceutical composition for preventing or treating a cardio-cerebrovascular disease, and a pharmaceutical composition may be provided for preventing or treating a cardio-cerebrovascular disease, which comprises one or more selected from the group consisting of a compound represented by the following Chemical Formula 1 and a pharmaceutically acceptable salt thereof as an active ingredient. | 2022-08-25 |
20220265580 | COMPOSITIONS COMPRISING EPHEDRINE OR AN EPHEDRINE SALT AND METHODS OF MAKING AND USING SAME - The present disclosure provides compositions comprising ephedrine sulfate ready for immediate use in a clinical setting, and methods of making and using same. | 2022-08-25 |
20220265581 | TREATMENT OF MENSTRUAL CYCLE-INDUCED SYMPTOMS - The present invention relates to methods of treatment of menstrual cycle induced disorders and symptoms with cathinone, particularly methods employing 3-methyl methcathinone (3-MMC). The present invention also relates to kits comprising 3-MMC for use in the treatment of subjects suffering from menstrual cycle induced disorders and symptoms. In particular, methods and kits for therapy of menstrual cycle induced disorders and symptoms with 3-MMC for a variety of disorders and/or conditions, including PMS, PMDD and perimenstrual disorders are provided. | 2022-08-25 |
20220265582 | EFFECTS OF MESCALINE AND OF MESCALINE ANALOGS (SCALINES) TO ASSIST PSYCHOTHERAPY - A method of inducing psychedelic states in an individual, by administering mescaline, a salt thereof, analogs thereof, or derivatives thereof to the individual, and inducing a psychedelic state in the individual. A method of therapy, by administering an intermediate “good effect dose” of mescaline, salt of mescaline, analogs thereof, or derivatives thereof to an individual, and inducing positive acute drug effects that are known to be associated with more positive long-term responses in psychiatric patients. A method of therapy, by administering an “ego-dissolution” dose of mescaline, a salt of mescaline, analogs thereof, or derivatives thereof to an individual, and providing the experience of ego-dissolution. | 2022-08-25 |
20220265583 | METHODS AND COMPOSITION FOR TREATING RESPIRATORY OBSTRUCTIVE DISEASES - The disclosure provides for methods and compositions for treating respiratory obstructive diseases. | 2022-08-25 |
20220265584 | Combination Therapies for Managing Cancer - This disclosure relates to methods of managing cancer and tumor growth. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering a combination of chemotherapy agents, wherein a first chemotherapy agent is capable of inhibiting oxidative phosphorylation of pyruvate and a second chemotherapy agent is capable of inhibiting glucose metabolism. In certain embodiments, the first and second chemotherapy agents are administered in combination with an additional chemotherapy agent. | 2022-08-25 |
20220265586 | SUSTAINED-RELEASE COMPOSITIONS OF ALPHA-KETOGLUTARATE - In certain embodiments, sustained-release compositions of alpha-ketoglutarate are described herein. | 2022-08-25 |
20220265587 | ESTER COMPOUNDS CONTAINING POLYOL AND SACCHARIDE GROUPS EFFECTIVE IN TREATING HEPATOTOXICITY AND USES THEREOF - The present invention relates to compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof. The present compound is represented by Formula (II), which has the formula: R | 2022-08-25 |
20220265588 | STABILIZED FORMULATIONS OF 4-AMINO-3-SUBSTITUTED BUTANOIC ACID DERIVATIVES - Pharmaceutical compositions including an active ingredient and a stabilizer, as well as methods of manufacture of the compositions, and methods of their use. The composition may include the active ingredient dispersed throughout a matrix of the stabilizer. In some embodiments, the active ingredient and the stabilizer are intimately mixed in a matrix formulation. In some embodiments, the active ingredient is selected from 4 amino-3-(4-chlorophenyl)butanoic acid) (“baclofen”) and its pharmaceutically acceptable salts. | 2022-08-25 |
20220265589 | METHOD OF ADMINISTERING A DUAL THERAPEUTIC AND COSMETIC AGENT - The method of administering a dual therapeutic and cosmetic agent provides for the transdermal application of a single agent which has both therapeutic and cosmetic uses. The composition containing the dual therapeutic and cosmetic agent is selected for therapeutic use, cosmetic use, or a combination thereof. An effective amount of the dual therapeutic and cosmetic agent is transdermally delivered to a recipient in need thereof based on whether therapeutic or cosmetic use is selected. The transdermal delivery may be performed by applying the dual therapeutic and cosmetic agent to skin of the recipient in combination with application of a microneedle array to the skin of the recipient. The application of the dual therapeutic and cosmetic agent to skin of the recipient may be performed before, after or with application of the microneedle array to the skin of the recipient. | 2022-08-25 |
20220265590 | DIBENZYLAMINES AS AMINO ACID TRANSPORT INHIBITORS - These compounds are amino acid transporter inhibitors. Amino acid transporter inhibitors are useful to treat a variety of diseases disorders, or conditions including cancer. | 2022-08-25 |