36th week of 2014 patent applcation highlights part 29 |
Patent application number | Title | Published |
20140248317 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND - A trehalose compound having high immunopotentiating activity and low toxicity is represented by formula (1). (In the formula, X and X′ each represents a phenyl, a naphthyl, R | 2014-09-04 |
20140248318 | NATURAL ANTIOXIDANT ANTI-INFLUENZA COMPOSITION - The invention relates to a composition from the extract of | 2014-09-04 |
20140248319 | MULTICOMPONENT AND BIOCOMPATIBLE NANOCOMPOSITE MATERIALS, METHODS OF SYNTHESIZING SAME AND APPLICATIONS OF SAME - One aspect of the present invention relates to a method of synthesizing a multicomponent and biocompatible nanocomposite material, which includes: synthesizing a gold/hydroxyapatite (Au/HA) catalyst; distributing the Au/HA catalyst into a thin film; and heating the thin film in a reactor with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD) to form the nanocomposite material, where the nanocomposite material includes a graphene structure and Au/HA nanoparticles formed by the Au/HA catalyst and distributed within the graphene structure. In another aspect, a multicomponent and biocompatible nanocomposite material includes: a graphene structure formed with a plurality of graphene layers and Au/HA nanoparticles distributed within the graphene structure. The nanocomposite material is formed by heating an Au/HA catalyst thin film with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD). | 2014-09-04 |
20140248320 | ADJUVANTED INFLUENZA B VIRUS VACCINES FOR PEDIATRIC PRIMING - The influenza B strain is epidemiologically relevant in the pediatric population. Immunogenic priming of children with influenza B vaccine adjuvanted with an oil-in-water emulsion primes an immune response to a booster vaccine comprising influenza B virus antigen from a different strain or lineage, irrespective of whether the booster comprises an adjuvant. | 2014-09-04 |
20140248321 | POWDERY EMULSIFYING COMPOSITION OF ALKYL POLYGLYCOSIDES, USE THEREOF FOR PREPARING COSMETIC EMULSIONS, AND METHOD FOR PREPARING SAME - A powdery composition C1 contains for 100% of the mass: 5 to 70 mass % and more particularly 10 to 50 mass % of at least one compound of formula (I): R—O-(G) | 2014-09-04 |
20140248322 | DENTAL COMPOSITIONS CONTAINING SILICA MICROBEADS - A dental treatment system for the relief of dental hypersensitivity and related disorders, including a dentition delivery formulation and a plurality of generally spherical vitreous microspheres generally homogeneously dispersed in the dentition delivery formulation, wherein each respective microsphere has a coating containing calcium and phosphate and wherein each respective microsphere is between about 0.01 micron and about 10 microns in diameter. | 2014-09-04 |
20140248323 | POWDERY EMULSIFYING COMPOSITION OF ALKYL POLYGLYCOSIDES, USE THEREOF FOR PREPARING COSMETIC EMULSIONS, AND METHOD FOR PREPARING SAME - A powdery composition C1 contains for 100% of the mass: 5 to 70 mass % and more particularly 10 to 50 mass % of at least one compound of formula (I): R—O-(G) | 2014-09-04 |
20140248324 | NOVEL MULTIPHASIC BIOMATERIALS AND METHOD OF MANUFACTURING SAME - The novel biomaterial fillers containing cross-linked sodium alginate and the method for manufacturing same are used in the medical field and are intended for filling tissue lesions having a layered structure of varying compositions, such as cartilage, skin or the epithelium. These novel biomaterials have the special feature of being multiphasic, composite and functionalized, for medical use and, in particular, for treating tissue lesions having a layered structure of varying compositions. The biomaterials are particularly suitable for treating focal lesions of the articular cartilage. | 2014-09-04 |
20140248325 | CELL-FREE TISSUE REPLACEMENT FOR TISSUE ENGINEERING - The present invention is a natural, cell-free tissue replacement that does not require difficult or extensive preparation made by washing tissue replacement in a solution including one or more sulfobetaines and an anionic surface-active detergent and washing the tissue replacement in serial solutions of the buffered salt to remove excess detergent. The natural, cell-free tissue replacement may be a nerve graft that supports axonal regeneration, guides the axons toward the distal nerve end and/or is immunologically tolerated. Other forms of the invention are a composition and kit prepared by the method of making a native, cell-free tissue replacement. The present invention may be modified for use in diagnostic, therapeutic, and prophylactic applications. | 2014-09-04 |
20140248326 | ENCAPSULATED KIDNEY TISSUE - Provided are therapeutic implants comprising renal tissue encapsulated within a polymer bead. Also disclosed are methods for treating a disease state in a subject comprising implanting within said subject a therapeutic implant comprising renal tissue encapsulated within a polymer bead. Also provided are methods for making a therapeutic implant comprising: providing renal tissue; mixing the renal tissue with a solution comprising a polymer, thereby forming a tissue-polymer suspension; extruding the tissue-polymer suspension into an bead-forming solution, thereby forming a therapeutic implant comprising beads of said polymer within which the renal tissue is encapsulated. | 2014-09-04 |
20140248327 | INTERVENTIONAL MEDICAL DEVICE AND MANUFACTURING METHOD THEREOF - An interventional medical device and manufacturing method thereof. The interventional medical device comprises: a stent body ( | 2014-09-04 |
20140248328 | Methods of treating amniotic membranes using supercritical fluids and compositions and apparatuses prepared therefrom - A method of sterilizing compositions prepared from amniotic membrane tissues may include harvesting placental tissue, separation of amniotic membrane tissue, and treatment of the amniotic membrane tissue with a supercritical fluid such as carbon dioxide. Treatment with supercritical fluid may subject the amniotic membrane tissue to conditions sufficient to sterilize the tissue yet maintain at least some biological function of the sterilized composition. Compositions described herein may be used as tissue grafts, wound dressings, cell culture substrates, or other substrates for use in tissue engineering. | 2014-09-04 |
20140248329 | Therapeutic Implant - Surgical implants of the present disclosed include a film comprising a first therapeutic agent and a mesh comprising a second therapeutic agent. The surgical implant includes a film in direct contact with a mesh. The first therapeutic agent may be released at a first rate and the second therapeutic agent may be released at a second rate. | 2014-09-04 |
20140248330 | DEVICE FOR TRANSDERMAL ADMINISTRATION OF DRUGS INCLUDING ACRYLIC POLYMERS - A transdermal delivery system is provided where the drug delivery rates, onset and profiles of at least one active agent are controlled by selectively manipulating the monomeric make up of an acrylic-based polymer in the transdermal drug delivery system. The drug carrier composition may be comprised of (a) one or more acrylic-based polymers having one or more different monomers selected from the group consisting of hard and soft monomers; (b) one or more silicone-based polymers; and (c) one or more active agents where the device provides a desired solubility for the active agent and controls drug delivery rates, onset and profiles of at least one active agent. | 2014-09-04 |
20140248331 | Polyhydroxyalkanoate Medical Textiles and Fibers - Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate. These devices provide a wider range of in vivo strength retention properties than are currently available, and could offer additional benefits such as anti-adhesion properties, reduced risks of infection or other post-operative problems resulting from absorption and eventual elimination of the device, and competitive cost. The devices may also be particularly suitable for use in pediatric populations where their absorption should not hinder growth, and provide in all patient populations wound healing with long-term mechanical stability. The devices may additionally be combined with autologous, allogenic and/or xenogenic tissues to provide implants with improved mechanical, biological and handling properties. | 2014-09-04 |
20140248332 | COMPOSITION COMPRISING AN ONION EXTRACT AND LIPOSOMES - The present invention relates to a composition comprising a first onion extract (A), and liposomes, wherein at least a portion of the onion extract is encapsulated in the liposomes. Furthermore the present invention relates to a method for preparing a composition comprising a first onion extract (A), and liposomes, wherein at least a portion of the onion extract is encapsulated in the liposomes. Further, the present invention relates to a composition comprising an onion extract (A) ( | 2014-09-04 |
20140248333 | COMPOSITIONS AND METHODS FOR INHIBITING PROTEASES - In particular, in alternative embodiments, the invention provides pharmaceutical compounds and formulations comprising a family of epoxyketone compounds, which include racemic mixtures or racemates, isomers, stereoisomers, diastereoisomers, derivatives and analogs, and methods for making and using them. In alternative embodiments, pharmaceutical compositions and formulations of the invention are administered to an individual in need thereof in an amount sufficient to treat, prevent, reverse and/or ameliorate an infection, disease or condition that can be ameliorated, treated, prevented or reversed by partially or completely inhibiting a chymotrypsin-like protease or a proteasome activity, including e.g., a retroviral infection such as human immunodeficiency virus-1 (HIV-1) infection, an immune disorder, a neurodegenerative disease or condition, or a cancer such as a myeloma or multiple myeloma, an adenocarcinoma such as a lung adenocarcinoma, a pancreatic cancer, a B-cell related cancer, and lymphomas such as non-Hodgkin's lymphoma. | 2014-09-04 |
20140248334 | PEPTIDES THAT TARGET DORSAL ROOT GANGLION NEURONS - The present invention concerns methods and compositions that employ peptides that target dorsal root ganglion (DRG) neurons. In particular, the peptides are used to target therapeutic agents, such as proteins, liposomes, or viral particles comprising therapeutic polynucleotides, to one or more peripheral neuropathies or neuropathic pain, for example. In particular cases, the peripheral neuropathies or neuropathic pain is caused directly or indirectly by DRG neuronopathy. | 2014-09-04 |
20140248335 | COMPOSITIONS OF MULTICATIONIC DRUGS FOR REDUCING INTERACTIONS WITH POLYANIONIC BIOMOLECULES AND METHODS OF USE THEREOF - The present invention relates, in part, to a composition comprising a multicationic drug and an organic multianion. In some embodiments, the multicationic drug is enclosed within a carrier. In some embodiments, the carrier is a liposome. In some embodiments, the multicationic drug and organic multianion are enclosed within a carrier, while in other embodiments, the multicationic drug is enclosed within the carrier and the organic multianion is outside the carrier. The present invention also relates, in part, to a method of treating a subject for pulmonary distress comprising administering to a subject in need thereof the aforementioned composition. | 2014-09-04 |
20140248336 | SIRNA USEFUL IN THE TREATMENT OF FLAVIVIRUS INFECTION - Pharmaceutical compositions that comprise an siRNA molecule used in the treatment of diseases caused by flavivirus infection and methods of their use are disclosed. The pharmaceutical compositions treat diseases caused by yellow fever virus, West Nile virus, and dengue virus and include a single pharmaceutical composition active against all four dengue virus serotypes. | 2014-09-04 |
20140248337 | Liposomal Vaccine Compositions Comprising a Polysaccharide Antigen and a Protein Adjuvant - A liposomal composition, preferably a vaccine, comprising liposomes formed of liposome forming compounds, containing coentrapped polysaccharide antigen and T-cell dependent protein carrier, such as tetanus toxoid or diphtheria toxin modified to render it non-toxic. The invention is of use in the production of vaccines against | 2014-09-04 |
20140248338 | COMPOSITIONS AND METHODS FOR SILENCING ALDEHYDE DEHYDROGENASE - The present invention provides compositions comprising therapeutic nucleic acids such as interfering RNA (e.g., dsRNA such as siRNA) that target aldehyde dehydrogenase (ALDH) gene expression, lipid particles comprising one or more (e.g., a cocktail) of the therapeutic nucleic acids, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles (e.g., for treating alcoholism in humans). | 2014-09-04 |
20140248339 | MULTI-COMPONENT NANOCHAINS - A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles. | 2014-09-04 |
20140248340 | COATED CONTROLLED RELEASE ACTIVE AGENT CARRIERS - The present invention relates to carriers for the controlled release of active agents, comprising a core, comprising surface reacted natural or synthetic calcium carbonate, and at least one active agent, wherein said at least one active agent is associated with said natural or synthetic surface-reacted calcium carbonate, and wherein said surface-reacted natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source, and a coating encapsulating the core. It furthermore relates to the preparation of loaded carriers, as well as their use in different applications. | 2014-09-04 |
20140248341 | ALCOHOL RESISTANT ENTERIC PHARMACEUTICAL COMPOSITIONS - Pharmaceutical formulations that resist ethanol-induced dose dumping and methods of use thereof. | 2014-09-04 |
20140248342 | Fe(III) 2,4-Dioxo-1-Carbonyl Complexes For Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anaemias - The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use in the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias. | 2014-09-04 |
20140248343 | ABUSE RESISTANT FORMS OF EXTENDED RELEASE MORPHINE, METHOD OF USE AND METHOD OF MAKING - An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided. | 2014-09-04 |
20140248344 | ABUSE RESISTANT FORMS OF EXTENDED RELEASE MORPHINE, METHOD OF USE AND METHOD OF MAKING - An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided. | 2014-09-04 |
20140248345 | PHARMACEUTICAL COMPOSITIONS OF COMBINATIONS OF DIPEPTIDYL PEPTIDASE-4 INHIBITORS WITH ATORVASTATIN - This invention relates to a bilayer pharmaceutical compositions comprising fixed-dose combinations of a dipeptidyl peptidase-4 inhibitor and atorvastatin, or a pharmaceutically acceptable salt thereof, methods of preparing such pharmaceutical compositions, and methods of treating Type 2 diabetes with such pharmaceutical compositions. | 2014-09-04 |
20140248346 | MISUSE PREVENTATIVE, CONTROLLED RELEASE FORMULATION - Disclosed is a misuse preventative, controlled release composition in the form of a multilayered oral dosage form. A first layer contains a plurality of controlled release microparticles having a pharmaceutically active agent (for example, an opioid analgesic) disposed therein. A second layer comprises a pharmaceutically active agent that can be the same or different from the pharmaceutically active agent in the microparticles. The composition further comprises a superabsorbent material disposed within the first layer, the second layer, or both the first layer and the second layer. When crushed, either intentionally or accidentally, and exposed to an aqueous medium, the superabsorbent material swells to encapsulate the microparticles, which remain substantially intact thereby retarding the release of the pharmaceutically active agent from the composition. | 2014-09-04 |
20140248347 | PHARMACEUTICAL COMPOSITIONS OF N-METHYL-2-[3-((E)-2-PYRIDIN-2-YL-VINYL)-1H-INDAZOL-6-YLSULFANYL]-BENZAMI- DE - The present invention relates to pharmaceutical compositions containing axitinib, which is known as N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-benzamide or 6-[2-(methylcarbamoyl)phenylsulfanyl]-3-E-[2-(pyridin-2-yl)ethenyl]indazole, or crystalline forms thereof, that protect axitinib from degradation, including photodegradation, as well as the therapeutic use of such compositions. The present invention also relates to novel photodegradants of axitinib. | 2014-09-04 |
20140248348 | USE OF SALMONELLA FLAGELLIN DERIVATIVE IN PREPARATION OF DRUG FOR PREVENTING AND TREATING INFLAMMATORY BOWEL DISEASES - The application of flagellin derivative CZLC31 from | 2014-09-04 |
20140248349 | PROCESS FOR THE PREPARATION OF A SOLID, ORALLY ADMINISTRABLE PHARMACEUTICAL COMPOSITION - The present invention relates to a process for the preparation of a solid, orally administrable pharmaceutical composition, comprising 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide in hydrophilized form, and its use for the prophylaxis and/or treatment of diseases. | 2014-09-04 |
20140248350 | DELAYED RELEASE FILM COATINGS CONTAINING CALCIUM SILICATE AND SUBSTRATES COATED THEREWITH - The present invention includes pH dependent, dry film coating compositions containing calcium silicate for use on orally-ingestible substrates such as tablets and the like. The film coating compositions can be applied as an aqueous suspension either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is either an enteric or reverse-enteric polymer. Methods of preparing the dry film coatings, methods of preparing corresponding aqueous suspensions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed. | 2014-09-04 |
20140248351 | PHARMACEUTICAL COMPOSITION COMPRISING FESOTERODINE - The present invention relates to a granulate and a pharmaceutical composition comprising fesoterodine or a salt or a solvate thereof and stabilizer, in particular to a pharmaceutical composition comprising fesoterodine or a salt or a solvate thereof and sucrose, polyethylene glycol, cyclodextrin, and combinations thereof and to a process for its preparation. The granulate and the pharmaceutical composition are particularly useful as a medicament, especially for the treatment of urinary incontinence. The present invention relates to use of sucrose, polyethylene glycol, cyclodextrin, and combinations thereof for stabilizing fesoterodine or a salt or a solvate thereof in a pharmaceutical composition. | 2014-09-04 |
20140248352 | CHEWABLE ENTERIC COATED ASPIRIN TABLETS - The invention relates to a tablet capable of being chewed or disintegrated in the oral cavity, which comprises an enteric coated aspirin active ingredient, and preferably a lightly compressed matrix comprising directly compressible carbohydrate(s) and at least one sweetener. | 2014-09-04 |
20140248353 | DOSAGE FORM FOR INSERTION INTO THE MOUTH - Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract. | 2014-09-04 |
20140248354 | CONTROLLED RELEASE VACCINES AND METHODS FOR TREATING BRUCELLA DISEASES AND DISORDERS - Methods and compositions for the treatment of | 2014-09-04 |
20140248355 | 1-[2-(2,4-Dimethylphenylsulfanyl)-Phenyl]Piperazine As A Compound With Combined Serotonin Reuptake, 5-HT3 And 5-HT1a Activity For The Treatment Of Cognitive Impairment - 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT | 2014-09-04 |
20140248356 | 1-[2-(2,4-Dimethylphenylsulfanyl)-Phenyl]Piperazine As A Compound With Combined Serotonin Reuptake, 5-HT3 And 5-HT1a Activity For The Treatment Of Cognitive Impairment - 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT | 2014-09-04 |
20140248357 | Respiratory Disease Treatment - A pharmaceutical composition adapted for pulmonary administration by inhalation is described, wherein the composition comprises a glitazone and one or more pharmaceutically acceptable carriers and/or excipients, wherein the glitazone content of the composition consists of at least 95% by weight of the 5R enantiomer and less than 5% by weight of the 5S enantiomer, and wherein the glitazone is pioglitazone or rosiglitazone or a pharmaceutically acceptable salt thereof, and wherein the glitazone is in the form of microparticles. | 2014-09-04 |
20140248358 | Therapeutic Nanoparticles Comprising a Therapeutic Agent and Methods of Making and Using Same - The present disclosure generally relates to nanoparticles comprising a substantially hydrophobic acid, a basic therapeutic agent having a protonatable nitrogen, and a polymer. Other aspects include methods of making and using such nanoparticles. | 2014-09-04 |
20140248359 | NOVEL FORMULATION OF DICLOFENAC - The present invention relates to methods for producing particles of diclofenac using dry milling processes as well as compositions comprising diclofenac, medicaments produced using diclofenac in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of diclofenac administered by way of said medicaments. | 2014-09-04 |
20140248360 | NANOPARTICLE TUMOUR VACCINES - The present invention provides a vaccine for the prophylactic or therapeutic treatment of a tumour in a mammalian subject, as well as methods of using the vaccine, including in treatment of tumours and in generating a CTL response. The vaccine comprises a plurality of nanoparticles and a pharmaceutically acceptable carrier, salt or diluents. The nanoparticles comprise a core comprising a metal and/or a semiconductor atom; and a corona comprising a plurality of ligands covalently linked to the core, wherein at least a first ligand of said plurality comprises a carbohydrate moiety that is covalently linked to the core via a first linker, and wherein at least a second ligand of said plurality comprises an epitopic peptide that is covalently linked to the core via a second linker, said second linker comprising a peptide portion and a non-peptide portion, wherein said peptide portion comprises the sequence X | 2014-09-04 |
20140248361 | HERBAL EXTRACT COMPOSITION AND A PROCESS THEREOF - A composition is provided that includes extracts of green tea and rosemary extract optionally along with adjuvant and/or excipient. In addition, provided is a process for the preparation of said composition. Also provided is a composition including extract of green tea, rosemary extract and synthetic antioxidant optionally along with adjuvant and/or excipient. | 2014-09-04 |
20140248362 | SUSTAINED-RELEASE PREPARATION - Provided is a sustained-release preparation containing pioglitazone or a salt thereof as an active ingredient and showing superior sustainability. A sustained-release preparation containing pioglitazone or a salt thereof, which shows a dissolution ratio of pioglitazone of average 25-58% at the 2-hour time point, and average 60-100% at the 4-hour time point, in a dissolution test according to the 50 rpm USP Paddle Method and using pH 2.0 KCl/HCl buffer at 37° C. as a test solution. | 2014-09-04 |
20140248363 | NANOPARTICULATE PHOSPHATE ADSORBENT ON THE BASIS OF MAGHEMITE OR MAGHEMITE/MAGNETITE, PRODUCTION AND USES THEREOF - The present invention relates to a phosphate adsorbent on the basis of maghemite or maghemite/magnetite comprising (i) an iron oxide core comprising a crystal structure of inverse spinel iron oxide, (ii) a coating selected from monomeric carbohydrates, in particular monosaccharides or disaccharides, alditols, or mixtures thereof, and/or (iii) a pharmaceutical excipient selected from polymeric carbohydrates, wherein the phosphate adsorbent has the form of nanoparticles with a particle size of the iron oxide core (i) of less than 20 nm. The present invention further relates to a method for the production of a phosphate adsorbent on the basis of maghemite or maghemite/magnetite, to pharmaceutical compositions comprising the phosphate adsorbent, and to medical uses thereof, especially for the prevention and/or treatment of hyperphosphatemia. | 2014-09-04 |
20140248364 | DIVALENT-METAL COATED NANOPARTICLES FOR DELIVERY OF COMPOSITIONS INTO THE CENTRAL NERVOUS SYSTEM BY NASAL INSUFFLATION - The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing nanoparticles to all regions of brain. It has been found that such divalent cation-containing nanoparticles, including those nanoparticles comprising manganese have affinity for the metal transport receptor proteins. Although this receptor has particular affinity for manganese, it is contemplated that other divalent ions, including magnesium, calcium, and the like may also be bound to such receptors leading to transport of the nanoparticles into the intracellular cytoplasm. Nanoparticles have been developed, therefore, as vehicles for parenteral delivery of genes, proteins and drugs. The present disclosure encompasses embodiments of nanoparticle-based compositions and methods for the use thereof for the delivery of genes, oligonucleotides, including but not limited to small interfering RNA, and other small molecule drugs, into the brain by nasal insufflation. | 2014-09-04 |
20140248365 | NANOPARTICLE PEPTIDE COMPOSITIONS - The present invention relates to teriparatide peptide-carrying nanoparticles, particularly for use in medicine, and includes methods for treatment of disorders, e.g., of bone density. Nanoparticle composition comprise a nanoparticle comprising a core comprising a metal and/or a semiconductor; and a corona comprising a plurality of ligands covalently linked to the core, wherein said plurality of ligands comprise at least one glutathione; and at least one teriparatide peptide that is non-covalently bound to the corona. | 2014-09-04 |
20140248366 | ANIMAL FEED COMPOSITION - The present invention relates to a feed composition for an animal comprising tea tree oil, wherein the tea tree oil is present in an amount sufficient to reduce bacterial infection in the animal upon ingestion of the feed composition, and to methods for preparing such a composition. | 2014-09-04 |
20140248367 | SPRAY-DRIED PHARMACEUTICAL COMPOSITIONS COMPRISING ACTIVE AGENT NANOPARTICLES - Provided herein are dry pharmaceutical compositions for transmucosal delivery, comprising spray-dried particles that include pharmaceutically active agent nanoparticles, a binder, and a pharmaceutically acceptable carrier, where the active agent nanoparticles have an average particle size diameter prior to spray-drying of less than about 1 μm, and wherein up to 10% of the spray-dried particles have a particle size of less than 10 μm; at least 50% of the spray-dried particles have a particle size of at least about 15 μm; and at least 90% of the spray-dried particles have a particle size of up to about 55 μm. Also provided are methods for making such pharmaceutical compositions and therapeutic methods comprising transmucosally administering the compositions, such as intranasally or intravaginally. | 2014-09-04 |
20140248368 | POWDERY EMULSIFYING COMPOSITION OF ALKYL POLYGLYCOSIDES, USE THEREOF FOR PREPARING COSMETIC EMULSIONS, AND METHOD FOR PREPARING SAME - A powdery composition C1 contains for 100% of the mass: 5 to 70 mass % and more particularly 10 to 50 mass % of at least one compound of formula (I): R—O-(G) | 2014-09-04 |
20140248369 | EYE HEALTH COMPOSITION AND METHOD USING PLANT DERIVED SEED EXTRACT RICH IN ESSENTIAL FATTY ACIDS DERIVED FROM PERILLA SEED AND CAROTENOIDS - A dietary supplement composition is formulated in a therapeutically effective amount to treat the eye of an individual. The composition includes a | 2014-09-04 |
20140248370 | Enhancement Composition - An enhancement composition includes a combination of natural ingredients that form a synergy to enhance the health, appearance, smell, and psyche of a surface, such as skin. Unnatural or processed ingredients are not included that can cause irritation and more detrimental effects to the skin. The enhancement composition has no preservatives because the particular combination of elements in the cream disclosed herein preserves the cream and permits a long shelf life. The enhancement composition is fabricated by combining, mixing, and sometimes heating predetermined amounts of Frankincense, Myrrh, black seed, and aloe. Additional ingredients can include, Shea butter, camel hump butter, coconut oil, olive oil, ginseng, natural resins, fatty acids, and various oils. The ingredients are combined by mixing, heating, cooling, distilling, or applying radiation. The composition promotes of spiritual health, particularly when implemented to include Frankincense and Myrrh. | 2014-09-04 |
20140248371 | SPALAX FIBROBLAST-DERIVED ANTI-CANCER AGENTS - A conditioned cell culture medium of cells derived from | 2014-09-04 |
20140248372 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO - The disclosure relates to compounds and compositions for bone formation, fracture treatment, bone grafting, bone fusion, cartilage maintenance and repair and methods related thereto. In certain embodiments, the disclosure relates to compositions comprising one or more compound(s) disclosed herein, such as clotrimazole, honokiol, magnolol, tacrolimus, pimecrolimus, sirolimus, everolimus, temsirolimus, spironolactone, fluticasone, fluticasone propionate, fluticasone furoate, linezolid, telmisartan, chlorambucil, retinol, isotretinoin, acitretin, etretinate, retinoic acid (tretinoin), teniposide, mitomycin C, cytarabine, decitabine, vinblastine, vincristine, vindesine, vinorelbine, valrubicin, doxorubicin, daunorubicin, epirubicin, idarubicin, mitoxantrone, pixantrone, plicamycin, pazopanib, topotecan, camptothecin, irinotecan, sunitinib, derivatives, or salt thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement. | 2014-09-04 |
20140248373 | ENHANCED PERFORMANCE HYDROGEN PEROXIDE FORMULATIONS COMPRISING PROTEINS AND SURFACTANTS - Disclosed herein are compositions comprising: an oxidizing agent; a surfactant; and a protein component. Also disclosed are methods of cleaning a surface, the method comprising applying an aqueous solution to the surface, the solution comprising the above compositions. | 2014-09-04 |
20140248374 | COMPOSITIONS AND MULTI-STEP METHODS OF USING THE SAME FOR THE TREATMENT OF JELLYFISH STINGS - Embodiments of the invention relate to a composition containing zinc and copper and methods of using the same in treatment of exposure to a pore-forming toxin (PFT) in a subject or membrane perturbant (MP). | 2014-09-04 |
20140248375 | Combination Therapy for Treating Proliferative Diseases - The present invention relates generally to new chemical combinations and methods for their use in the treatment of proliferative diseases and in particular cancer. | 2014-09-04 |
20140248376 | COMPOSITIONS FOR TREATMENT OF SKIN AND EAR INFECTIONS - The present invention relates to a composition for the treatment of skin and ear infections in humans and animals such as dogs, cats and horses. In particular, the present invention relates to a topical composition comprising acetic acid, an antibacterial and/or an anti-fungal, and preferably also an anti-inflammatory. More specifically, the composition of the present invention is a bandage, bedding, clothing, conditioner, cream, drape, dressing, film, foam, gauze, gel, lotion, mousse, otic solution, pad, patch, serum, shampoo, solution, spray, or wipe for treatment or prevention of skin infections, wherein the composition comprises about 0.1-10% acetic acid, about 0.1-10% boric acid, about 0.01-20% azole, and optionally about 0.01-20% corticosteroid. | 2014-09-04 |
20140248377 | MULTIPLE EMULSION - The invention relates to a multiple emulsion for the application of at least one pharmaceutical or cosmetic active ingredient which has an external water phase W | 2014-09-04 |
20140248378 | PYRIMIDINONE COMPOUNDS AND THEIR USE - The present invention provides compounds of formula (1) and pharmaceutically acceptable salts thereof, wherein R | 2014-09-04 |
20140248379 | PROCESS FOR PRODUCING AN EXTRACT CONTAINING TETRAHYDROCANNABINOL AND CANNABIDIOL FROM CANNABIS PLANT MATERIAL, AND CANNABIS EXTRACTS - The invention relates to a method for producing an extract from | 2014-09-04 |
20140248381 | COMPOSITION FOR INHIBITING VASCULAR AGING COMPRISING SYRINGARESINOL - The present invention discloses a composition for inhibiting vascular aging comprising a compound of Chemical formula 1, a derivative thereof or a pharmaceutically acceptable salt thereof as an active ingredient. | 2014-09-04 |
20140248382 | CURCUMINOID-BASED COMPOUND/STEVIOSIDE-CONTAINING COMPLEX FOR THE PREVENTION AND TREATMENT OF AN INFLUENZA VIRUS INFECTION - The present invention relates to a complex comprising a compound of formula (I), or a plant extract comprising the compound or a fraction thereof; and stevioside, or a plant extract comprising the stevioside or a fraction thereof, and relates to a pharmaceutical composition for preventing or treating an influenza virus infection comprising the complex as an active ingredient. Also, the present invention relates to a food composition for preventing or improving an influenza virus infection, a virucidal quasi-drug composition, a virucidal feed additive, and a feed, which comprises the complex as an active ingredient. According to the present invention, the complex comprising a compound of formula (I), or a plant extract comprising the compound or a fraction thereof; and stevioside, or a plant extract comprising the stevioside or a fraction thereof exhibits a virucidal effect and an effect of inhibiting cell degradation against an influenza virus as well as antiviral efficacy in a specific pathogen-free (SPF) chicken, and thus can be usefully used in the prevention and treatment of an influenza virus infection. | 2014-09-04 |
20140248383 | SLEEP QUALITY IMPROVING AGENT - An object is to provide a sleep quality improving agent that can sufficiently exert the effect of improving the quality of sleep and ensures safety for the body. A sleep quality improving agent containing, as an effective ingredient, a plant of the | 2014-09-04 |
20140248384 | MELT SPINNING DEVICE - A melt spinning device produces a plurality of multi-filament threads which includes a spinning apparatus, a cooling apparatus, a drawing apparatus and a winding apparatus. The drawing apparatus has a plurality of godet units entwined by threads, each of said units having a plurality of godets, which are axially rectified to a coil spindle of the winding device. The transition of the threads as yarn from the drawing device to the winding device is executed by a guide godet which is aligned axially crosswise to the godets of the godet units and under the drawing device, so that the threads can be guided by simple partial wrapping after rotation of the thread running plane of the yarn by 90°. | 2014-09-04 |
20140248385 | Coinjection Hot Runner Injection Molding System - A coinjection molding apparatus is disclosed that provides first and second material melt streams to a nozzle. The nozzle defines a first material melt passage for receiving the first material melt stream, a second material melt passage for receiving the second material melt stream and an outer layer melt passage, which receives a portion of the first material melt stream from the first material melt passage. The first material melt stream from the first material melt passage forms an inner layer of a molded article, the second material melt stream from the second material melt passage forms a core layer of the molded article, and the first material melt stream from the outer layer melt passage forms an outer layer of the molded article, wherein the three melt streams combine prior to entering a mold cavity. | 2014-09-04 |
20140248386 | CONTROLLER OF INJECTION MOLDING MACHINE - In an injection molding machine provided with an injection member (injection screw or plunger) having a check valve, a process position of the injection member such as a metering completion position or an injection speed switching position is changed at every predetermined cycle. Thus, it is possible to periodically change a position inside a cylinder which is easy to wear and to reduce the frequency of performing the maintenance of a purging or disassembling and cleaning. | 2014-09-04 |
20140248387 | METHOD AND SYSTEM FOR OPERATING AN INJECTION MOLDING MACHINE - According to embodiments of the present invention, there is provided a method and system for operating an injection molding machine. For example, a molding system ( | 2014-09-04 |
20140248388 | APPARATUS FOR PROCESSING PLASTIC MATERIAL - Disclosed is an apparatus for processing of plastics, with a container with a mixing implement, and a conveyor provided with a screw rotating in a housing, the housing being divided into two chambers, the frontal chamber having an intake aperture, and the rearward chamber having at least one degassing aperture, the two chambers being connected to one another through a channel having a melt filter, wherein the imaginary continuation of the longitudinal axis of the conveyor in a direction opposite to the direction of conveying passes the axis of rotation, wherein the distance from the opening of the channel into the rearward chamber to the degassing aperture is in a range from 1.5 to 15 times the nominal diameter (d) of the screw. | 2014-09-04 |
20140248389 | Multistep Reaction Lateral Flow Capillary - Disclosed is a lateral flow capillary device and uses thereof comprising a unipath bibulous capillary flow matrix and at least two reservoirs each in fluid communication with the capillary flow matrix wherein a reservoir contacts the capillary flow matrix through a passage having a rim pressing the matrix. The pressure that the rim applies on the matrix prevents leakage of liquids out of the capillary flow matrix at the reservoir/matrix interface, allowing accurate sequential draining of liquid from the reservoirs. During use of the disclosed lateral flow capillary device a static interface is formed between the first liquid and the second liquid in an interface creation zone inside the capillary flow matrix wherein the first amount and second amount are such that first liquid substantially remains in the first reservoir and the second liquid substantially remains in the second reservoir subsequent to the formation of the static interface and wherein the interface begins to move only subsequent to exhaustion of a liquid from a reservoir. | 2014-09-04 |
20140248390 | DECKLE TECHNOLOGY - The invention provides a deckle system for extrusion dies. In certain embodiments, the invention provides methods of cleaning an extrusion die equipped with a retractable external deckle system. Also provided in some embodiments is a deckle system having a novel deckle adjustment mechanism. In other embodiments, the invention provides an advantageous internal deckle member equipped with a removable, replaceable internally threaded insert. | 2014-09-04 |
20140248391 | USE OF INFANT FORMULA WITH LARGE LIPID GLOBULES - The invention relates to infant nutrition comprising large lipid globules. This infant nutrition has programming effects on the body and results in a reduced level of total blood cholesterol later in life when consuming a Western style diet. Thereby the risk on western life style diseases as atherosclerosis and other vascular diseases later in life can be reduced. | 2014-09-04 |
20140248392 | EDIBLE PRODUCT AND USE THEREOF FOR INCREASING BIOAVAILABILITY OF MICRONUTRIENTS COMPRISED IN VEGETABLES OR FRUIT - The present invention provides an oil containing edible product that is capable of increasing the bioavailability of one or more oil soluble micronutrients that are comprised in vegetables or fruit. One aspect of the invention relates to the use of a glyceride component for increasing the bioavailability of one or more micronutrients that are comprised in a vegetable or a fruit, said use comprising consuming an edible product containing at least 4 wt. % of said glyceride component within 30 minutes of consuming said vegetable or fruit, said glyceride component consisting of: •76-97 wt. % triglycerides; •0-8 wt. % diglycerides; •3-16 wt. % monoglycerides; and wherein the weight ratio diglycerides:monoglycerides is less than 1:2. Another aspect of the invention relates to an edible product that comprises 4-90 wt. % of the aforementioned glyceride component and 10-96 wt % of other components, wherein the glyceride component has a solid fat content at 10° C. (N | 2014-09-04 |
20140248393 | THIOESTERASES AND THEIR USE - Disclosed are nucleotide sequences encoding thioesterase enzymes, methods for their production, their use in methods to form thioesters, and their use in methods of screening for other wild type bacteria capable of producing said thioesterase enzymes. | 2014-09-04 |
20140248394 | Composition Comprising a Calcium Salt, Preparation Process and Use in Food Products - The invention concerns a composition comprising a calcium salt and its preparation process. The calcium salt is a salt of Ca | 2014-09-04 |
20140248395 | CELLULOSE TO PROTEIN BIO-CONVERSION METHOD FOR PRODUCTION OF EDIBLE PROTEIN - Animal feeds comprising fungal mass and proteinaceous material and methods for bioconverting cellulosic materials to produce the same are described. Also described are apparatuses for use in the methods. | 2014-09-04 |
20140248396 | Improved Viability of Probiotic Microorganisms Using Poly - gamm- Glutamic Acid - The invention relates to a probiotic microorganism at least partially coated with a poly glutamic acid, for example poly-γ-glutamic acid (γ-PGA). The invention also relates to an ingestible product comprising the probiotic microorganism at least partially coated with a poly glutamic acid and a method of making a probiotic microorganism at least partially coated with a poly glutamic acid. The invention also relates to a method of making poly-γ-glutamic acid (γ-PGA). | 2014-09-04 |
20140248397 | ALPHA-AMYLASE VARIANTS - A variant polypeptide having alpha-amylase activity, wherein the variant has an amino acid sequence which, when aligned with the alpha-amylase comprising the sequence set out in SEQ ID NO: 2, comprises at least one substitution of an amino acid residue corresponding to any of amino acids 4, 6, 13, 14, 15, 16, 20, 45, 47, 51, 54, 61, 68, 69, 70, 71, 72, 73, 74, 75, 77, 78, 80, 82, 87, 88, 94, 95, 100, 103, 104, 117, 124, 125, 126, 128, 130, 133, 134, 136, 143, 144, 146, 168, 174, 177, 178, 183, 186, 188, 189, 190, 194, 195, 199, 200, 201, 204, 207, 210, 214, 217, 219, 222, 225, 227, 233, 234, 235, 236, 240, 251, 252, 254, 258, 259, 260, 261, 262, 263, 264, 266, 267, 269, 271, 273, 281, 282, 283, 284, 286, 288, 299, 322, 323, 325, 327, 328, 331, 334, 350, 356, 358, 367, 370, 371, 374, 377, 378, 388, 391, 414, 421, 422, 445, 450, 467, 488, 505, 536, 548, 583, 588, 603, 637, 648, 651, 652, 660, 676, 677, | 2014-09-04 |
20140248398 | STABILISATION OF MICROWAVE HEATED FOOD SUBSTRATES - A food product having a substrate impregnated with a stabiliser composition and coated with an aqueous coating composition can be reheated using a microwave oven with good results. | 2014-09-04 |
20140248399 | BOURBON SOAKED PRETZEL PRODUCTS AND METHODS FOR MAKING THE SAME - The present invention provides for bourbon soaked pretzel products and methods for making the same. In certain embodiments of the present invention, the pretzels are dipped in a bourbon-butter mixture and then baked. In certain embodiments of the present invention, the pretzels are dipped a second time in a bourbon-butter mixture and then baked. | 2014-09-04 |
20140248400 | Edible Liquid Filled Polysaccharide Capsules - Edible capsules include a core surrounded by an encapsulating skin The core is liquid at 25° C. and includes an aqueous mixture of one or more carrageenans, one or more flavorants, and one or more food oils that in total constitute at least 0.5 wt % and at most 30 wt % of the core. The encapsulating skin includes an alginate crosslinked with one or more polyvalent cations, wherein the capsules are nonspherical and seamless. | 2014-09-04 |
20140248401 | DEPOSITED HARD SHELL AND SOFT CHEWY CENTER CANDY AND METHOD OF MAKING - A hard candy, namely lollipops, suckers or similar confectionary comestibles and a method of making and packaging the same by a depositing manufacturing process which produces a multi-colored and multi-flavored lollipop which colors and flavors extend entirely through the lollipop body and hard shell and are visible in the final packaging and particularly to a double depositing method and apparatus incorporating a soft chewy center into a deposited lollipop body which soft center is entirely surrounded by and of a different consistency and viscosity from the hard outer candy shell. | 2014-09-04 |
20140248402 | RESEALABLE FOOD CONTAINER - A polygonal shaped container is provided which includes a wrapper surrounding a food product. The shape of the container is defined by either a frame containing a food product or rigid material incorporated with the wrapper. Access to contents in the container is provided by withdrawing a resealable sealing layer sealed to the top or side surface of the container and withdrawing the sealing layer from the container or by pivoting a rigid lid away from the top of the container. | 2014-09-04 |
20140248403 | APPARATUS FOR DELIVERING MULTIPLE COMESTIBLE COMPONENTS IN A SIMULTANEOUS AND ORGANOLEPTICALLY PLEASING MANNER - An apparatus for delivering a multi-state or multi-component comestible, comprising a sealed pouch or tube containing one component of the comestible which surrounds, either fully or on multiple sides, one or more other components, housed in one or more separated tubes or compartments. The apparatus' unique delivery, wherein one component surrounds the other component(s) as it is expulsed into the consumer's mouth, greatly enhances the consumer's organoleptic experience. The consumer's organoleptic experience may be further enhanced by the shape and/or location of the tubes/pouches of the apparatus, which, based on the specific comestible being delivered, can be modified to speed up or slow down delivery of individual comestible components into the consumer's mouth, and to provide greater control over the outflow of individual components of the multi-component comestible. | 2014-09-04 |
20140248404 | METHOD AND APPARATUS FOR VITAMIN D ENHANCEMENT IN DRIED MUSHROOM POWDER - An apparatus and method for increasing Vitamin D content in dried mushroom powder irradiates the powder with UV light with wavelengths in the range of about 200 to about 800 nanometers. The powder may be conveyed into the light chamber with a vibratory conveyor. The irradiated mushroom powder has an elevated Vitamin D2 level of at least 14,000 IU/gram. | 2014-09-04 |
20140248405 | METHOD AND APPARATUS FOR THERMAL CONDITIONING OF OLIVES OR OTHER OLEAGINOUS FRUITS COMBINED WITH A CRUSHING AND KNEADING SYSTEM OF OLIVES OR OTHER OLEAGINEOUS FRUITS IN CONTROLLED OR MODIFIED ATMOSPHERE - A method and an apparatus for thermal treatment of olives or other oleaginous fruits are described. The method and apparatus are for crushing in controlled or modified atmosphere and for kneading in controlled or modified atmosphere, allowing to reduce the kneading times, improving the working capacity of the line, concomitantly preserving the quality of the product. | 2014-09-04 |
20140248406 | Fruit Product Containing Sugar Alcohol - A processed fruit product, for example a citrus fruit product, including a packing liquid, containing little or no sugar, and optionally containing one or more artificial sweeteners, further comprising an amount of a sugar alcohol effective to maintain integrity and/or texture of the fruit. | 2014-09-04 |
20140248407 | RETORT STERILIZATION DEVICE, HEATING DEVICE, HEAT STERILIZATION METHOD AND HEAT TREATMENT METHOD - A retort sterilization device includes a water steam generation device for generating water steam and a heating pot, connected to the water steam generation device, for accommodating retort food. The water steam generation device includes a heat exchanger for performing heat exchange between liquid flowing in a liquid path and heating vapor flowing in the vapor path. A top end of the liquid path of the heat exchanger is connected via a water steam supply pipe to a water steam ejection section located in an internal area of the heating pot. The heat exchanger is connected to a liquid container. A bottom end of the liquid path of the heat exchanger is connected to the liquid container via a communicating tube. The liquid container is coupled to the heating pot. | 2014-09-04 |
20140248408 | DEVICE AND METHOD FOR THE HIGH-PRESSURE TREATMENT OF PRODUCTS - The present disclosure relates to a device for the high-pressure treatment of products, particularly of packaged foodstuffs. The device comprises a high-pressure chamber and a discharge valve for discharging high-pressure medium out of the high-pressure chamber. The invention is characterized in that a controllable actuator is provided for adjusting the rate of the pressure decrease in the high-pressure chamber at least over a predetermined pressure range. The disclosure also relates to a method for the high-pressure treatment of products, wherein pressure decrease takes place in a first phase and in a second phase, and the mean pressure decrease rate in the first phase is higher than in the second phase. | 2014-09-04 |
20140248409 | Raw Bone Product and Method - A raw bone product including ground raw bone compressed into a mass, wherein the ground raw bone has been subjected to a hydrostatic pressure of at least 4000 atm for a predetermined amount of time, and wherein the mass is maintained at a temperature of at most 40° F. | 2014-09-04 |
20140248410 | CAROTENOID-CONTAINING COMPOSITION AND METHOD FOR PRODUCING SAME - A carotenoid-containing composition including: a carotenoid component containing a crystalline carotenoid that is in an amorphous state; a (poly)glycerol fatty acid ester that contains from one to six glycerol units and from one to six fatty acid units and has at least one hydroxyl group resulting from a glycerol unit; a fatty acid ester component which is at least one selected from the group consisting of triesters of glycerol and fatty acids, and esters of alcohols having one hydroxyl group and fatty acids, contains no hydroxyl group in a molecule, and has from 10 to 60 carbon atoms in total; and an antioxidant. | 2014-09-04 |
20140248411 | SWEETNESS ENHANCER - A composition for enhancing sweetness includes glycan or glycopeptide derived from soy sauce. The composition has excellent sweetness enhancing properties, and particularly has a sweetening effect nearly the same as or better than those of conventional sweeteners and less calories in terms of nutritional characteristics. A sweetener composition includes the composition for enhancing sweetness and a sweetener. A food includes the composition for enhancing sweetness. A method for enhancing sweetness of a food, includes applying the sweetness enhancer composition to the food. The sweetness enhancer of the present invention is a natural product-derived substance, and contains, as an active ingredient, peptide separated from Korean traditional soy sauce aged over a long period of time, and therefore, may solve problems of conventional chemosynthesized sweetness enhancers, for example, side effects, foul taste or the like. | 2014-09-04 |
20140248412 | DRYBLENDED NUTRITIONAL POWDERS - Disclosed are reconstitutable nutritional powders comprising carbohydrate, protein, and lipid wherein at least one carbohydrate, such as lactose, and powdered lecithin have been dryblended into the reconstitutable nutritional powders. Also disclosed are methods of manufacturing a reconstitutable nutritional powder including dryblending at least one carbohydrate and powdered lecithin into a base nutritional powder. The nutritional powders provide for reduced foaming upon reconstitution. | 2014-09-04 |
20140248413 | FILLING SWEET (VARIANTS) AND METHOD FOR MAKING SAME - The invention relates to the food industry. The sweet contains a protein mass and a high-boiled sugar mass. The high-boiled sugar mass consists of sugar and/or a sugar substitute and water, and the protein mass consists of wheat flour and gram flour or pea meal or a composition thereof and melted fat, preferably real butter. The method for making the sweet involves the concurrent preparation of the protein mass and the high-boiled sugar mass. The sweet is then shaped in the form of a layered product made up of fine fibres by the repeated stretching of the high-boiled sugar mass and the saturation thereof with the protein mass. The group of inventions makes it possible to produce a sweet in the style of a pastry which is comprised of fine, readily separating fibres and has an enhanced biological and nutritional value and digestibility and an increased shelf life. | 2014-09-04 |
20140248414 | GLYCOMACROPEPTIDE MEDICAL FOODS FOR NUTRITIONAL MANAGEMENT OF PHENYLKETONURIA AND OTHER METABOLIC DISORDERS - Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria. | 2014-09-04 |
20140248415 | NUTRITIONAL PRODUCTS COMPRISING HUMAN MILK OLIGOSACCHARIDES AND METHODS FOR MANUFACTURE THEREOF - A method for the manufacture an infant formula or an infant nutritional product comprising mixture of human milk oligosaccharides is disclosed. The method involves the catalytic hydrogenolysis of compounds of the general formula 1 and 2 with particular oligosaccharide profiles. | 2014-09-04 |
20140248416 | Apparatus and Method for Producing Controlled Dosage of Bioactive Agent - An apparatus for producing a controlled dosage of bioactive agent is disclosed. The apparatus includes: a print device to eject a drop of a mixture onto an ingestible substrate, wherein the drop of mixture includes a bioactive agent within an ingestible carrier fluid and is between 50 ng and 1000 ng in size; a charge generating device adjacent to the print device to generate charge on the bioactive agent to draw the bioactive agent to the ingestible substrate; a cold fluid removal device adjacent to the charge generating device to remove a portion of the ingestible carrier fluid from the bioactive agent; an application device adjacent to the cold fluid removal device to apply an ingestible layer on top of the ingestible substrate encapsulating the bioactive agent or to fold the ingestible substrate on top of the bioactive agent encapsulating the bioactive agent; and a transfer device adjacent to the print device, the charge generating is device, the cold fluid removal device, and the application device to move the ingestible substrate from one device to the next. | 2014-09-04 |
20140248417 | Coatings for the Manufacture and Application of Polyhydroxyalkanoate Medical Devices - Biocompatible coatings and spin finishes that can be applied to polyhydroxyalkanoate (PHA) polymers, and medical devices made from PHA polymers, have been developed. The coatings impart good lubricity to PHA polymers, particularly to fibers and braids made from these materials, making the coatings ideal for use on medical devices such as PHA braided sutures. The spin finishes can be applied to PHA fibers to facilitate their manufacture, and also for their conversion to other products, including medical textiles. The spin finishes serve to protect multifilament fiber bundles, and keep them intact following extrusion, and also to impart lubricity to the fiber bundles and monofilament fibers so that they are not damaged in subsequent processing steps particularly in textile processing. The coating reduces tissue drag of, for example, braided sutures. | 2014-09-04 |