36th week of 2014 patent applcation highlights part 39 |
Patent application number | Title | Published |
20140249320 | Process for Preparing 5-biphenyl-4-amino-2-methyl Pentanoic Acid - The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, | 2014-09-04 |
20140249321 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE y, -POSITION - The present invention relates in a first aspect to a process for hydrogenation of ketones having at least a carbon-carbon double bond in the y,8-position to the keto group by hydrogen in the presence of at least one chiral iridium complex of formula (I), where R1 represents a group of formula (II) or (III) or (IV). It has been shown that this process leads to a strong increase in preferential formation of a single isomer. The process is particularly suitable for the hydrogenation of y,8-unsaturated ketones which can be used as flavours and fragrances or for the preparation of vitamin E and its derivatives or of flavours and fragrances. | 2014-09-04 |
20140249322 | MAKING EPOXIDIZED ESTERS FROM EPOXIDIZED NATURAL FATS AND OILS - Processes are described for making epoxidized fatty acid esters from epoxidized natural fats and oils, wherein low moisture fats and oils are identified and selected or made and used in a transesterification process. The products undergo phase separation, and reduced molar excesses of alcohol may be employed compared to processes not employing a low moisture feedstock. | 2014-09-04 |
20140249323 | PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR - The complex of the present invention containing an onium salt and a central Lewis acidic metal has a high catalytic activity at a high temperature for the copolymerization of an epoxide and carbon dioxide to produce a high molecular weight polycarbonate. | 2014-09-04 |
20140249324 | Copper-Indium-Gallium-Chalcogenide Nanoparticle Precursors for Thin-Film Solar Cells - Nanoparticles containing IUPAC group 11 ions, group 13 ions and sulfur ions are synthesized by adding metal salts and an alkanethiol in an organic solvent and promoting the reaction by applying heat. Nanoparticles are formed at temperatures as low as 200° C. The nanoparticles may be thermally annealed for a certain amount of time at a temperature lower than the reaction temperature (usually ˜40° C. lower) to improve the topology and narrow the size distribution. After the reaction is complete, the nanoparticles may be isolated by the addition of a non-solvent and re-dispersed in organic solvents including toluene, chloroform and hexane to form a nanoparticle ink. Additives may be incorporated in the reaction solution to tailor the final ink viscosity. | 2014-09-04 |
20140249325 | SILICIC ACID POLYCONDENSATES HAVING CYCLIC OLEFIN-CONTAINING STRUCTURES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF - The present invention relates to silicic acid (hetero) polycondensates comprising structural units of a following formula (1) | 2014-09-04 |
20140249326 | Method of Synthesizing Siloxane Monomers and Use Thereof - A method for preparation and polymerization of siloxane monomers of Formula I is presented. The synthesis includes the selective reaction between silanol containing unit and alkoxy containing units in the presence of basic catalyst. The siloxane monomers of the invention can be used for preparation of siloxane polymers with good flexibility and cracking threshold, and functional sites, useful for applications requiring low metal content in semiconductor industry. | 2014-09-04 |
20140249327 | METHOD FOR PRODUCING NITRILE COMPOUNDS FROM ETHYLENICALLY UNSATURATED COMPOUNDS - The present invention relates to a method for the hydrocyanation of organic ethylenically unsaturated compounds including at least one nitrile function. The invention specifically relates to a method for the hydrocyanation of a hydrocarbon compound including at least one ethylenic unsaturation by a reaction with hydrogen cyanide in a liquid medium and in the presence of a catalyst including a metal element selected from the transition metals and an organophosphorous ligand, the organophosphorous gaud including a compound of general formula (I), where R | 2014-09-04 |
20140249328 | FORMULATIONS - This invention relates to a formulation comprising a compound of formula (I) where R1 and R2 are each independently hydrogen, optionally substituted C1-18 alkyl, optionally substituted C1-18 alkenyl, optionally substituted C3-8 cycloalkyl, optionally substituted C3-8 cycloalkenyl or optionally substituted aryl; provided that the total number of carbon atoms in R1 and R2 is an integer from 5 to 40 inclusive; the use of a compound of formula (I) (i) as an adjuvant provided that the total number of carbon atoms in R1 and R2 is an integer from 5 to 40 inclusive; and (ii) as a solvent provided that the total number of carbon atoms in R1 and R2 is an integer from 5 to 20 inclusive; to certain novel compounds of formula (I) and to a process for preparing those novel compounds. | 2014-09-04 |
20140249329 | C-HALOGEN BOND FORMATION - Methods of halogenating a carbon containing compound having an sp3 C—H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provided. Methods of direct oxidative C—H fluorination of a carbon containing compound having an sp3 C—H bond are provided. The halogenated products of the methods are provided. | 2014-09-04 |
20140249330 | METHOD FOR THE PRODUCTION OF AN AQUEOUS SOLUTION OF SALTS - The invention relates to a method for the continuous production of a solution of salts, in particular for the production of hexamethylenediamine adipate and a device for implementing such a method. According to the invention, it is proposed to convert, in a first step, a substoichiometric quantity of alkane diamine in a ratio to the alkane dicarboxylic acid in water and, in a subsequent second step, to implement making-up with alkane diamine, adjustment of the stoichiometric ratios being effected via a pH value measurement at a constant temperature. | 2014-09-04 |
20140249331 | PROCESS FOR PREPARING KETONES FROM EPOXIDES - A process for preparing a ketone by conversion of a compound E which contains an epoxy group to the ketone in the presence of a mixture comprising at least one noble metal and at least one metal oxide as a catalyst system, wherein the metal oxide in the catalyst system is at least one of titanium dioxide and zirconium dioxide, and the process is conducted at 0 to 0.9 bar of hydrogen. | 2014-09-04 |
20140249332 | METHODS FOR SELECTIVE OXIDATION OF ALPHA TOCOTRIENOL IN THE PRESENCE OF NON-ALPHA TOCOTRIENOLS - A method of producing alpha-tocotrienol quinone or a stereoisomer thereof, the method comprising selective opening of alpha-tocotrienol chroman to alpha-tocotrienol quinone in the presence of non-alpha tocotrienol chromans by oxidizing alpha-tocotrienol with a metal salt oxidizing agent, wherein the stoichiometric ratio of metal salt oxidizing agent/alpha-tocotrienol is at least 4:1 and wherein said metal oxidizing agent is added in sequential additions, in order to reduce oxidation of any amounts of non-alpha tocotrienol chromans that might have been present in the starting alpha-tocotrienol chroman material. This process uses conditions favoring oxidation rates of the alpha tocotrienol chroman vs the non-alpha tocotrienol chromans. | 2014-09-04 |
20140249333 | Apparatus for Coproducting ISO Type Reaction Products and Alcohols From Olefins, and Method for Coproducting Them Using The Apparatus - The present invention relates to an apparatus for coproducting iso-type reaction product and alcohol from olefin, and a method for coproducting using the apparatus, in which the hydroformylation reactor provides a sufficient reaction area due to the broad contact surface area between the olefin and the synthesis gases that are the raw materials by a distributor plate installed in the reactor, and the raw materials can be sufficiently mixed with the reaction mixture due to the circulation of the reaction mixture so that the efficiency of the production of the aldehyde is excellent; and also the hydrogenation reactor suppresses the side reaction so that the efficiency for producing aldehyde and alcohol are all increased, and also iso-type reaction product and alcohol can be efficiently co-produced. | 2014-09-04 |
20140249334 | CATALYST FOR POLYOL HYDROGENOLYSIS - Ethylene glycol and propylene glycol may be made by hydrogenolysis of a polyol comprising the steps of reacting a polyol with hydrogen in the presence of a hydrogenolysis catalyst. The hydrogenolysis comprises nickel, one or more promoter, and one or more support. The promoter is selected from bismuth, silver, tin, antimony, gold, lead, thallium, cerium, lanthanum, and manganese. The support is selected from zirconia and carbon. A zirconia support comprises a zirconia textual promoter, which is selected from Cr, Mo, W, Nb, Ce, Ca, Mg, La, Pr, Nd, Al, and P. If the support comprises carbon, then the promoter is selected from bismuth and antimony. In another embodiment, if the support comprises carbon, then both the promoter is selected from bismuth and antimony, and the catalyst comprises copper. In another embodiment, the catalyst additionally comprises copper. | 2014-09-04 |
20140249335 | Chemical Production Processes and Systems - Hydrogenolysis systems are provided that can include a reactor housing an Ru-comprising hydrogenolysis catalyst and wherein the contents of the reactor is maintained at a neutral or acidic pH. Reactant reservoirs within the system can include a polyhydric alcohol compound and a base, wherein a weight ratio of the base to the compound is less than 0.05. Systems also include the product reservoir comprising a hydrogenolyzed polyhydric alcohol compound and salts of organic acids, and wherein the moles of base are substantially equivalent to the moles of salts or organic acids. Processes are provided that can include an Ru-comprising catalyst within a mixture having a neutral or acidic pH. A weight ratio of the base to the compound can be between 0.01 and 0.05 during exposing. | 2014-09-04 |
20140249336 | PROCESS FOR PRODUCING 2-CHLORO-3,3,3-TRIFLUOROPROPENE - This invention provides a process for producing 2-chloro-3,3,3-trifluoropropene, comprising: reacting anhydrous hydrogen fluoride with at least one chlorine-containing compound selected from the group consisting of chloropropanes and chloropropenes represented by specific formulas in a gas phase in the presence of a chromium atom-containing fluorination catalyst while heating, the reaction being carried out in the presence of molecular chlorine or with a water content in the reaction system of 300 ppm or less. This invention enables suppression of catalyst deterioration and efficient production of 2-chloro-3,3,3-trifluoropropene in a simple and economically advantageous manner on an industrial scale. | 2014-09-04 |
20140249337 | METHOD FOR EXTRACTING HYDROCARBONS WITH MEDIUM CHAIN LENGTHS, AND THE USE OF THE SAME - The invention relates to a method for extracting hydrocarbon mixtures that have an increased proportion of hydrocarbons of a medium chain length (8 to 16 carbon atoms), or the corresponding pure compounds. Firstly, a starting material is provided that includes at least 50 wt. % unsaturated hydrocarbon compounds having oxygen. The compounds include olefin fragments of the formula —C | 2014-09-04 |
20140249338 | COMPOSITIONS OF MATTER COMPRISING EXTRACTED ALGAE OIL - Crude algae oils produced by practical extraction techniques comprise a wide range of molecular species that can be characterized by advanced analytical techniques. The algae oils comprise a complex mixture of a large number of molecules having varying sizes and therefore varying boiling points, and comprise high nitrogen, oxygen, and fatty acid content, but low sulfur, saturated hydrocarbons, and triglyceride content. Hydrogen/carbon molar ratios are typically greater than 1.6. The wide range of molecular species in the crude algae oils, while unusual compared to conventional refinery feed stocks and vegetable oils, may be upgraded into fuels by conventional refining approaches such as hydrotreating and thermal treatment. Unusual behavior of the algae oils in thermal processing and/or hydrotreatment may provide a high quality product slate, with the flexibility to adjust the product slate due to enhanced cracking behavior exhibited by these algae oils. | 2014-09-04 |
20140249339 | COMPLEX COMPRISING OXIDATIVE DEHYDROGENATION UNIT - Oxidative dehydrogenation of paraffins to olefins provides a lower energy route to produce olefins. Oxidative dehydrogenation processes may be integrated with a number of processes in a chemical plant such as polymerization processes, manufacture of glycols, and carboxylic acids and esters. Additionally, oxidative dehydrogenation processes can be integrated with the back end separation process of a conventional steam cracker to increase capacity at reduced cost. | 2014-09-04 |
20140249340 | PROCESS FOR THE PRODUCTION OF MIDDLE DISTILLATES FROM A FEEDSTOCK COMPRISING BUTANOL AND PENTANOL - The invention relates to a process for the production of middle-distillate hydrocarbon-containing bases from a feedstock comprising butanol and pentanol, with said process comprising at least:
| 2014-09-04 |
20140249341 | COMBINED XYLENE ISOMERIZATION AND TRANSALKYLATION PROCESS UNIT - The xylene isomerization process unit and the transalkylation process units are combined in the present invention. A fractionation column can be shared by the two units, reducing the capital cost of the complex. In some embodiments, a split shell fractionation column and a split separator can be used. | 2014-09-04 |
20140249342 | Renewable fuels produced from oleaginous microorganisms - Disclosed herein are methods of manufacturing renewable chemicals through the manufacture of novel triglyceride oils followed by chemical modification of the oils. Methods such as transesterification, hydrogenation, hydrocracking, deoxygenation, isomerization, interesterification, hydroxylation, hydrolysis and saponification are disclosed. Novel oils containing fatty acid chain lengths of C8, C10, C12 or C14 are also disclosed and are useful as feedstocks in the methods of the invention. | 2014-09-04 |
20140249343 | METHOD AND CATALYST FOR THE ALKYLATION OF AROMATIC COMPOUNDS WITH ALKANES - Disclosed is a process for the direct alkylation of aromatic compounds with alkanes. To this end a judicious catalyst combination is provided. The composition comprises palladium as a catalytically active metal, and zinc as a promoter, or a metal such as tin having a comparable promoting action. The metals are contained in a zeolite support, or a similar support of a metal organic framework type or a silico alumino phosphate type. | 2014-09-04 |
20140249344 | PROCESS FOR PREPARING A MESOPORIZED CATALYST, CATALYST THUS OBTAINED AND USE THEREOF IN A CATALYTIC PROCESS - The invention relates to a process for preparing a catalyst comprising a mesoporized zeolite, comprising the steps of:
| 2014-09-04 |
20140249345 | Apparatus And Methods For Vaporization And Remediation Of Radioactive Contamination - An aspect of the present disclosure relates to a method for collecting volatile radioactive substances. The method includes irradiating a volatile radioactive substance on or under a contaminated material surface using microwave radiation and vaporizing the volatile radioactive substance, wherein the volatile radioactive substance comprises at least one of cesium and iodine. The method further includes recovering the vaporized volatile radioactive substance from the contaminated material. The method may be accomplished with and/or without physically collecting or isolating the contaminated material. | 2014-09-04 |
20140249346 | PROCESS FOR STABILIZING WASTE - The process for stabilizing wastes generally comprises blending spent or virgin fullers earth with a hazardous or non-hazardous sludge, soil or sediment to form a matrix. Next, the matrix is blended with a reagent capable of growing a calcium silicate hydrate or Ettringite mineral. In this manner a more stable, less leachable product is formed. | 2014-09-04 |
20140249347 | USE OF PYRIDONE DERIVATIVES IN THE PREVENTION OR TREATMENT OF TISSUE OR ORGAN TOXICITY INDUCED BY CYTOTOXIC AGENTS AND RADIATION - The present invention is directed to a novel use of pyridone derivatives such as pirfenidone for the prevention and treatment of damages to tissues or organs induced by various cytotoxic agents, such as chemotherapeutic agents, biologics, immunosuppressants and radiation. Such prophylactic and/or therapeutic effects of the pyridone derivatives make it possible to increase therapeutic dosages of the cytotoxic agent, thereby enhancing the therapeutic efficacy of the cytotoxic agent and radiation therapy. | 2014-09-04 |
20140249348 | METHOD AND APPARATUS FOR EMISSION GUIDED RADIATION THERAPY - An apparatus comprising a radiation source, coincident positron emission detectors configured to detect coincident positron annihilation emissions originating within a coordinate system, and a controller coupled to the radiation source and the coincident positron emission detectors, the controller configured to identify coincident positron annihilation emission paths intersecting one or more volumes in the coordinate system and align the radiation source along an identified coincident positron annihilation emission path. | 2014-09-04 |
20140249349 | VALVELESS PET INFUSION SYSTEM - A device for delivery of a radiopharmaceutical and, in some embodiments, delivery of a pharmaceutical agent are provided herein. | 2014-09-04 |
20140249350 | APPARATUS FOR FRACTIONATION AND INFUSION OF RADIOPHARMACEUTICAL PRODUCTS - Apparatus for fractionation and infusion of radiopharmaceuticals, including a fractionation unit ( | 2014-09-04 |
20140249351 | MICROPARTICLES FOR SELECTIVELY TARGETED HYPERTHERMIA - A microparticle composition(s) comprising nanomagnetic particles and a matrix, wherein said microparticle composition(s) have a least one of the following properties: (a) a VAR of at least about 1 Watts/cm3 subject to appropriate field conditions; (b) a density of about 2.7 or less: or (c) a size of about 100 nm to about 200 microns. | 2014-09-04 |
20140249352 | TRANSCRANIAL MAGNETIC STIMULATION SYSTEM AND METHODS - A system and methods for transcranial magnetic stimulation, the system including a helmet, a positioning portion, a stimulator and a cooling system, are disclosed. The helmet includes a coil for deep brain magnetic stimulation. The coil has a base portion, and return portions, which may include a protruding return portion and a contacting return portion. The coil is designed to minimize unintended stimulation of portions of the brain, while reducing accumulation of surface charges. The coil is stimulated at several locations and/or at different times so as to focus the electrical field on a specific deep neuronal structure. | 2014-09-04 |
20140249353 | Method and apparatus for determining effects of transcranial magnetic stimulation to a brain - The present invention relates generally to a method and apparatus for determining one or more cumulative effects of an application of transcranial magnetic stimulation to the brain of a subject, as well as a method and apparatus of representing same. According to an aspect of certain embodiments of the invention there is provided a method for determining one or more cumulative effects of an application of transcranial stimulation to one or more locations in a brain of a subject comprising the steps of applying multiple transcranial magnetic stimulation pulses to the brain, determining a dose of each of said stimulation pulses, measuring a physical response of the user and determining or approximating an accumulation of said response of said brain for each of said one or more locations in the brain of said subject. | 2014-09-04 |
20140249354 | IMMERSIVE, FLUX-GUIDED, MICRO-COIL APPARATUS AND METHOD - A PEMF web using immersive, flux-guided, micro-coils to direct intense, deeply penetrating, magnetic flux into a subject from each micro-coil capable of pointing in an arbitrary direction. Micro-coils are spooled around iron cores, insulated properly, and soldered to connecting wires, all embedded in a polymeric resin, such as cold-cured silicone resin. Nodes protect, enclose, insulate electrically, and otherwise protect the micro-coils. Connectors between nodes provide mechanical stability against breaking of wires, while permitting folding, bending, buckling, and otherwise deflecting to position the nodes as desired with three degrees of freedom. | 2014-09-04 |
20140249355 | PULSED ELECTROMAGNETIC FIELD DEVICE WITH ADHESIVE APPLICATOR - Systems and techniques for applying an electromagnetic field to bodily tissue include a self-contained and portable electromagnetic field generating device adhered to a surface with an adhesive composition on the applicator such that the radiated electromagnetic fields impinge upon the bodily tissue. The adhesive composition may include a therapeutic substance such as a rubefacient and/or one or more additives. The device includes an electromagnetic field generator, which is coupled to an antenna that is arranged to radiate the electromagnetic field. A power source is coupled to the generator to provide power for the device and an activator is used to initiate radiation of the electromagnetic field. | 2014-09-04 |
20140249356 | Intelligent Nanomagnetic Cardiac Assist Device for a Failing Heart - The present invention is directed to a contractible and expandable jacket configured to encase at least a portion of a patient's heart. The jacket has a plurality of individual contractile cells with each of the cells having a first electrically conductive coil and a second electrically conductive coil spaced from the first coil. The first coil preferably defines at least in part a first periphery of an inner nucleus of the cell and the second coil preferably defining at least in part an outer portion of the cell spaced outwardly from the inner nucleus. When electrical current passes through the first and second coils in opposite directions, the cell contracts and when electrical current passes through the first and second coils in the same direction the cell expands. Each of the individual cells has conductive appendages for conducting information to and from the individual cells. | 2014-09-04 |
20140249357 | DEVICES, METHODS AND SYSTEMS FOR ESTABLISHING SUPPLEMENTAL BLOOD FLOW IN THE CIRCULATORY SYSTEM - A cannula for insertion through a biologic tissue. The cannula includes a shaft having proximal and distal end portions with a lumen therebetween. The cannula further includes a tip having a proximal end portion, a distal tip end, and a lumen therebetween. The proximal end portion of the tip is secured to the distal end portion of the shaft so that the lumen of the tip is in fluid communication with the lumen of the shaft. The tip includes an opening that extends proximally relative to the distal tip end to permit the flow of fluid into the lumen of the tip even in the event that the distal tip end becomes obstructed. | 2014-09-04 |
20140249358 | Systems and Methods for Music Therapy - Systems and methods for using particular types of music compositions having certain characteristics to treat depression and related disorders, autism, and other disorders are described. The music for use in music therapy efforts includes characteristics for modification of the psycho-physiological apparatus and response including the use of vocal invented language elements to simulate pre-verbal communication and elements to coincide with and work with natural chrono-biological and circadian rhythms. For example, activating elements are provided in some compositions that are to be played immediately prior to a peak of chrono-biological activity. As another example, other compositions include de-activating elements to improve relaxation immediately prior to a natural low of chrono-biological activity. Such activating and de-activating elements include musical elements such as changes of volume, frequency selection, and tempo. The compositions may be used to treat depression and other disorders based on timing and application of music therapy using the compositions. | 2014-09-04 |
20140249359 | SOUND MACHINE WITH PSEUDO RANDOM WHITE NOISE GENERATOR - A sound machine having a pseudo random white noise generator provides white noise sound therapy of selectable tone/texture, bandwidth and/or peak frequency to those suffering from tinnitus or others seeking noise-masking or sleep or relaxation. The sound machine having a pseudo random white noise generator includes a user input interface having a tone/texture user input control, a band pass user input control and a peak select user input control. The tone/texture user input control selects the tone/texture of the white noise sound generated, the bandpass user input control the bandpass of the white noise sound generated and the peak select user input control provides the ability to select frequency peaks of the white noise sound generated. | 2014-09-04 |
20140249360 | SYSTEM FOR PROVIDING BIOFEEDBACK - The invention relates to a system ( | 2014-09-04 |
20140249361 | SYSTEM AND METHOD FOR NERVE STIMULATION - A system and method for stimulating a target such as a nerve, wherein the system includes a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating a predetermined target of the mammal, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the mammal, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the mammal, and adapted to apply the modulated waveform thereto. | 2014-09-04 |
20140249362 | IMPLANTABLE MESH COMBINING BIODEGRADABLE AND NON-BIODEGRADABLE FIBERS - Disclosed are mesh materials adapted for use in an implantable sling. The mesh materials include biodegradable and non-degradable components that may be adapted to facilitate scar-tissue ingrowth as the biodegradable components degrade. | 2014-09-04 |
20140249363 | METHOD FOR EVALUATING HUMAN BLASTOCYST BY NOREPINEPHRINE LEVEL IN BLASTOCYST CULTURE SOLUTION - The invention provides a new method for evaluating transfer embryos including blastocysts used for in vitro fertilization in fertility treatment, and a method for evaluating transfer embryos using a new biomarker necessary for evaluation. The method comprises the steps of (a) providing a test object, for example, a culture solution of a human blastocyst, containing norepinephrine (noradrenaline) released from a transfer embryo, such as a human blastocyst, obtained from a subject; (b) quantitatively analyzing norepinephrine in the test object by a combination of ultra high performance liquid chromatography and mass spectrometry or the like; (c) predicting the quality of the transfer embryo based on the amount of norepinephrine from analysis results obtained; and (d) transferring the embryo into a suitable female recipient for implantation, if the transfer embryo is predicted to be of good quality and/or to lead to the establishment of a viable pregnancy based on step (c). | 2014-09-04 |
20140249364 | OOCYTES DERIVED FROM OVARIAN CULTURE INITIALLY CONTAINING NO OOCYTES - Ovarian germ-line-competent embryonic stem cells (GLC-ESC) are cultured, either in the presence or absence of a compound having estrogenic activity. The GLC-ESC are either collected prior to specific commitment or are permitted to remain in the culture medium for a time sufficient to develop into oocytes, and the oocytes may be fertilized by adding sperm to the culture medium. The fertilized oocytes may be permitted to develop into embryos, which may be transferred into the uterus of an adult human female or frozen for later use. The invention provides a method for obtaining by in vitro fertilization an embryo that is genetically related to a human female who is not producing oocytes. | 2014-09-04 |
20140249365 | DEVICE AND METHOD FOR REPAIR OF UROLOGICAL STRUCTURES - A tissue engineering construct made from a nonwoven fabric. The fabric is made from first and second staple fibers. The first staple fibers are made from a first biocompatible, bioabsorbable material, and the second staple fibers are made from a second biocompatible, bioabsorbable material. The first material has a melting temperature lower than the second material. The fabric is formed into a three-dimensional construct suitable for the repair of urinary tract structures. | 2014-09-04 |
20140249367 | MINIMALLY INVASIVE SURGICAL STABILIZATION DEVICES AND METHODS - The various embodiments of the present inventions provide stabilization devices and methods for use of the stabilization devices with minimally invasive gynecological procedures such as methods of preventing pregnancy by inserting intrafallopian contraceptive devices into the fallopian tubes | 2014-09-04 |
20140249368 | METHOD OF PACKAGING IMAGING DEVICE CHIP, METHOD OF ASSEMBLING ENDOSCOPE, IMAGING MODULE, AND ENDOSCOPE - An endoscope includes: an imaging device chip having a chip connection portion; a tubular housing tube used to a scope tip portion of an endoscope; a substrate to which the imaging device chip is fixed, the substrate having a substrate connection portion, the substrate being capable of bending at near the substrate connection portion when the substrate is inserted into the housing tube; a lead wire connecting the substrate connection portion and the chip connection portion; flexible and non-conductive resin covering an entirety of the lead wire; and an imaging module including the substrate provided with the imaging device chip thereon, the imaging module inserted into the housing tube. | 2014-09-04 |
20140249369 | IMAGING APPARATUS AND RIGID ENDOSCOPE - An aim is to provide an imaging apparatus that can reduce the size without being constrained by the size of a mechanism that drives the apparatus, and can accurately move a field of view over a wide range in a narrow space. The apparatus includes an image-wise light receiving means, a spherical housing that holds therein the image-wise light receiving means, a base that supports the spherical housing and enables the spherical housing to freely move along a surface thereof, a drive wire having an end fixed to the spherical housing, and a drive section to which the other end of the drive wire is fixed to drive the free movement of the spherical housing via the drive wire. | 2014-09-04 |
20140249370 | System and Method for Cleaning a Cannula during a Surgical Procedure - Cannula and scope cleaning apparatus and associated methods of use are provided which allow for the clearing/cleaning of a cannula and cleaning of a viewing scope during a medical procedure, wherein the apparatus can be configured such that the viewing scope need not be removed from within the cannula in order for debris and/or fogging to be removed from a lens portion of the scope. In particular embodiments, the cannula and scope cleaning apparatus can be deformable, having an adjustable lumen therein such that when the apparatus can be disposed within a cannula, viewing scopes having various outside diameter sizes can be slidably introduced and stabilized within a cannula. | 2014-09-04 |
20140249371 | OPTICAL TROCAR SYSTEM - An optical trocar system that includes an elongated obturator member having a first diameter. The elongated obturator member has a distal region, the distal region having a first diameter section having a diameter that is substantially equal to the first diameter of the elongated obturator member. The elongated obturator member has a second diameter section having a diameter that is less than the first diameter. The optical trocar system also includes an optical member attached to the distal region of the elongated obturator member such that the optical member encapsulates the second diameter section of the elongated obturator member and at least a portion of the first diameter section. A longitudinal bore through the elongated tubular obturator member is configured to receive an endoscope. | 2014-09-04 |
20140249372 | RIGID-ENDOSCOPE OVERSHEATH - A rigid-endoscope oversheath having a leading end, a base end, a longitudinal shaft, and a lumen into which a rigid endoscope can be inserted, the oversheath including a flow path through which fluid flows from the base end toward the leading end along the longitudinal shaft, an ejection port formed in a same plane with a leading end plane of the rigid-endoscope oversheath to eject the fluid flowing through the flow path from the leading end plane of the flow path, a peripheral portion of the port being at least partially composed of an elastic member deformable by the fluid flowing through the flow path, and a valve at least partially attached to a leading end of the flow path to openably close the leading end of the flow path. | 2014-09-04 |
20140249373 | Displaying Image Data From A Scanner Capsule - An ingestible image scanning pill captures high resolution images of the GI tract as it passes through. Images communicated externally have exact location determination. Image processing software discards duplicate information and stitches images together, line scan by line scan, to replicate a complete GI tract as if it were stretched out in a straight line. A fully linear image is displayed to a medical professional as if the GI tract had been stretched in a straight line, cut open, laid flat out on a bench for viewing—all without making any incisions in a live patient. | 2014-09-04 |
20140249374 | SYSTEMS, DEVICES AND METHODS FOR CREATING AN OPERATIVE SITE WITHIN A PATIENT - A device for creating an operative space within a body lumen for the performance of a medical procedure, including a pressurizable, expandable balloon element insertable into the body lumen. The balloon element includes an interior space for receiving an inflation fluid. The device further includes an ingress valve coupled with the balloon element and insertable therewith into the body lumen. The ingress valve is capable of being opened to allow the interior space to be filled with the inflation fluid and closed to retain the inflation fluid in the interior space. The device may also include an egress valve coupled with the balloon element and insertable therewith into the body lumen. The egress valve is closed when the interior space is filled with the inflation fluid and is capable of being opened to allow the inflation fluid to vent from the interior space. | 2014-09-04 |
20140249375 | Surgical Access System Including Surgical Portal Apparatus and Adhesive Patch - The present disclosure relates to surgical access systems and methods of using the same to access a surgical site during a surgical procedure. The surgical access system includes a portal member and a patch. The portal member includes at least one longitudinal port for passage of a surgical object. The portal member is formed from a compressible material and is adapted to transition from a first expanded condition to a second compressed condition such that an outer surface of the portal member is adapted for a substantial sealing relation with an opening in tissue upon insertion of the portal member therethrough. The patch includes a non-porous substrate having a tissue facing surface including an adhesive for positioning over the opening in the tissue and sealing a surface thereof. The patch is adapted for sealed reception of the portal member. | 2014-09-04 |
20140249376 | LIGHT SOURCE APPARATUS FOR MEDICAL USE - A medical-use light-source apparatus includes a light source lamp, a connector to which a body cavity endoscope and an ophthalmic observation apparatus can be selectively connected, a determiner which determines whether the body cavity endoscope or the ophthalmic observation apparatus is currently connected to the connector, and a lamp controller which sets a value of a maximum light amount of the illumination light to a first threshold value when the determiner determines that the body cavity endoscope is currently connected to the connector, and sets a value of a maximum light amount of the illumination light to a second threshold value that is smaller than the first threshold value when the determiner determines that the ophthalmic observation apparatus is currently connected to the connector. | 2014-09-04 |
20140249377 | Well defined system and method for monitoring neurological disease onset and progress and onset of the effects of neuropharmacological drugs using the recency-primacy shift and overall free recall differences - Given free recall or recognition test results of normal and disease populations, the present innovation provides methods for determining how close a single test subject is to the profile of a diseased population. The methods use the total items remembered and a defined recency-primacy shift to determine how similar the test subject is to a disease population. The methods are well defined and do not involve any “tinkering”. | 2014-09-04 |
20140249378 | SYSTEMS, METHODS AND KITS FOR MEASURING COUGH AND RESPIRATORY RATE USING AN ACCELEROMETER - The disclosures is directed to cough detectors, methods and kits. Cough detectors can include, for example, a housing adaptable to engage an abdomen or thorax of a mammal; a first sensor comprising an AGM sensor positioned within the housing; a processor in communication with the AGM sensor wherein the processor is capable of receiving a signal from the AGM sensor and analyzing the signal to determine whether the signal is characterizable as a cough; and a power source. | 2014-09-04 |
20140249379 | METHODS FOR MONITORING HEALTH, WELLNESS AND FITNESS WITH FEEDBACK - A method is provided for obtaining monitored information about an individual to create life activity data. Individual information is detected or measured. The individual information is selected from of at least one of, an individual's activities, behaviors and habit information, and an individual's health. A monitoring device is used to detect or measure the individual information. The monitoring device includes ID circuitry with an ID storage that contains a unique individual ID, a communication system which reads and transmits the unique individual ID from the ID storage, a power source and a pathway system. The individual information is received from the monitoring device at a telemetry system that includes a database. The individual information is analyzed using life activity data with one or more analysis tools at the telemetry system. Life activity data is created for the individual. | 2014-09-04 |
20140249380 | Methods for Diagnosing Perceived Age Based On An Ensemble Of Phenotypic Features - The present invention relates to an algorithm by which phenotypic features of individuals can be calculated and classified to evaluate the overall health of an individual, and particularly skin aging. More particularly, the present invention relates to methods and systems for diagnosing the perceived age of an individual. The invention also relates to methods useful to define products or treatments to reduce the perceived age, to evaluate the efficacy of products and treatments, and to benchmark the product or treatments in order to determine its market value and customer claims. | 2014-09-04 |
20140249381 | LIGHT-GUIDING DEVICES AND MONITORING DEVICES INCORPORATING SAME - A sensor module for detecting and/or measuring physiological information from a subject includes a housing with at least one optical emitter and at least one optical detector supported by the housing. A first light guide is in optical communication with the at least one optical emitter and is configured to deliver light from the at least one optical emitter into a body of a subject. A second light guide is in optical communication with the at least one optical detector and is configured to collect light from the body of the subject. The sensor module includes a motion sensor and a processor. The motion sensor is configured to sense motion information from the subject and the processor is configured to remove motion artifacts from signals produced by the at least one optical detector in response to signals produced by the motion sensor. | 2014-09-04 |
20140249382 | MOTION DETECTION SYSTEM - A motion detection system for detecting movement and/or breathing from a subject, e.g., for preventing SIDS, can incorporate a sensor in communication with a fluid-filled chamber while optionally combining audio and/or video monitoring systems. The sensor module may have a housing which can be attached, e.g., to an article of clothing worn by the subject. The sensor may be entirely enclosed within the housing which may also be filled with a vibrationally transmissive medium which transmits movements from the subject such that these signals impinge upon the sensor which captures these signals (or the absence of these signals) for processing and possibly alerting a parent or caretaker. | 2014-09-04 |
20140249383 | BREATHING GUIDANCE APPARATUS FOR DELIVERY ROOMS - A system to prompt a subject to consciously alter one or more physiological parameters during childbirth-related contractions includes an imaging subsystem, a contraction sensor, and various computer program modules. The computer program module are configured to determine a physiological parameter, contraction information, a target action rate, and cues based thereon. The physiological parameter may include a breathing rate. The target action rate may include a target breathing rate. The cues may include breathing cues. | 2014-09-04 |
20140249384 | ESTIMATION OF THE DRY WEIGHT OF A DIALYSIS PATIENT - In an embodiment, the invention relates to methods, apparatus, computer programs and computer program products for estimating a dry weight of a dialysis patient comprising the steps of determining a first fluid status of the patient between treatment sessions in a first stage, determining a second fluid status of the patient during treatment sessions in a second stage and estimating the dry weight based on the second fluid status. | 2014-09-04 |
20140249385 | HEADBAND, HEADGEAR, AND ELECTROENCEPHALOGRAPHIC APPARATUS - To provide a headband capable of correctly placing an electrode on a head of a user, a headband apparatus includes a plurality of headband portions integrally connected and configured to be positioned about a head of a user, wherein at least two headband portions are each configured to be positioned behind an ear. | 2014-09-04 |
20140249386 | APPARATUS, SYSTEM AND METHODS FOR MEASURING A BLOOD PRESSURE GRADIENT - An apparatus ( | 2014-09-04 |
20140249387 | On-Body Medical Device Securement - Devices and methods for maintaining a medical device on-body are provided. Embodiments include medical device securement systems having first and second on-body securement elements. Also provided are systems and kits for use maintaining a medical device on-body. | 2014-09-04 |
20140249388 | METHOD AND APPARATUS TO SENSE HYDRATION LEVEL OF A PERSON - A hydration sensor or sensing element is configured to measure the hydration level of a user. The sensing element can include a water-permeable material positioned in between two water-impermeable material. The sensing element can be coupled to a bottle of fluid, or a carrier with a timer. The sensing element can be incorporated into a handheld device. The sensing element can be a disposable element, an element applicable for more than one-time use, or a re-usable element. The sensing element or sensor can be calibrated for a specific user or a group of users. One or more additional sensors that do not measure hydration level of the user can be coupled to a hydration sensing element to determine the amount of fluid consumption for the user in different conditions. | 2014-09-04 |
20140249389 | METHOD AND APPARATUS FOR TREATING SKIN PRIOR TO BIOSENSOR INSERTION - Embodiments of the present invention provide a device and method for treating animal skin to produce tautness in the skin during the insertion of an analyte sensor. A device in accordance with embodiments of the present invention includes a housing that partially encloses a cavity and is adapted for mounting onto animal skin and a sensor insertion module adapted to insert an analyte sensor through animal skin. | 2014-09-04 |
20140249390 | IN VIVO BLOOD SPECTROMETRY - A process and apparatus for determining the arterial and venous oxygenation of blood in vivo with improved precision. The optical properties of tissue are measured by determination of differential and total attenuations of light at a set of wavelengths. By choosing distinct wavelengths and using the measured attenuations, the influence of variables such as light scattering, absorption and other optical tissue properties is canceled out or minimized. | 2014-09-04 |
20140249391 | TISSUE VISUALIZATION FOR RESECTION - Methods for distinguishing between two interspersed biological tissues, for procedures such as surgical resection, include exposing the tissues to at least two components, a first of which components produces or is capable of producing a detectable signal, and the other of which components either blocks the produced signal of the first component or activates the first component to produce the detectable signal. One of the components is selectively taken up by one of the tissues at a concentration which is greater than the concentration by which it is taken up by the other tissue to provide a distinguishable difference in the detectable signal originating from the two tissues. | 2014-09-04 |
20140249392 | METHOD AND DEVICE FOR MEASURING DISSOLVED SUBSTANCES IN HUMAN OR ANIMAL INTRAOCULAR FLUID - Non-invasive optical measurement of glucose and other dissolved substances in human or animal intraocular fluid. A method takes advantage of the fact that the wave dependence of optical activity is fundamentally different from corneal birefringence. The optical activity of substances dissolved in the intraocular fluid, such as glucose, lactate, ascorbic acid or amino acids, is scaled as a first approximation with the reciprocal value of the wavelength square. In contrast, corneal birefringence is scaled with the reciprocal value of the wavelength and therefore behaves considerably different from the optical activity. For the method according to the invention, a physical model is used, which describes the influence on the polarization of measurement radiation by the components of the eye, particularly by the intraocular fluid and the cornea. | 2014-09-04 |
20140249393 | Wireless monitoring of patient exercise and lifestyle - A system is provided that uses using telemetry data based on a patient habit information or patient monitoring. One or more patient monitoring devices has a unique patient ID, with personalized patient information. A patient monitoring device includes an application for monitoring exercise activity of a patient. ID circuitry is at the patient monitoring device, which includes ID storage and a communication system that reads and transmits the unique ID from an ID storage. A power source and a pathway system routes signals through the circuitry. A telemetry system is in communication with the patient monitoring device and includes a database of patient ID's which is in communication with the patient monitoring device and analyzes patient information based on the patient ID. The telemetry system receives exercise-related information directly or indirectly from the monitoring device that indicates an amount or type of exercise performed by the patient. | 2014-09-04 |
20140249394 | HEALTH MONITORING AND DIAGNOSTIC DEVICE AND NETWORK-BASED HEALTH ASSESSMENT AND MEDICAL RECORDS MAINTENANCE SYSTEM - A health monitoring and diagnostic device (LIFESTREAM cholesterol meter) configured as a self-contained testing and diagnostic unit in a clam-shell type case. One side of the case includes a spring-loaded finger stick and a compartment for carrying one or more packages of disposable items including a test strip, a needle for the finger stick, and an alcohol swipe. The other half of the case includes a test strip reader, a key pad, and a liquid crystal display. The meter reads a test strip carrying a droplet of blood and receives additional diagnostic information from the patient, such as age, gender, weight, and family history of heart disease. Within minutes, the meter displays test results, including total cholesterol levels. The meter also displays additional diagnostic results, such as the patient's “cardiac age,” recommended weight loss, and a cardiac risk assessment. The meter also works in connection with a network-based comprehensive health analysis and reporting system. The meter writes patient data to a smartcard. This patient data typically includes patient identification information, the test results, the diagnostic information, and the diagnostic results. A computer station reads the smartcard and establishes a network connection with a health report server over the Internet. The computer then downloads the patient data to the health report server, which prepares a comprehensive health report. Within minutes, this report is transmitted back to the computer station, where it is printed out and delivered to the patient. | 2014-09-04 |
20140249395 | Implantable Electrochemical Biosensors for Retinal Prostheses - Progress has been made in the development of implantable electrochemical biosensors. However, to date a commercially-available long-term implantable biosensor is still out of reach. The foreign body response poses great challenges for long-term implantable devices. Retinal prostheses provide a platform for incorporation of biosensors for neural stimulation and biosensing in the human eye. | 2014-09-04 |
20140249396 | IL-1 RECEPTOR ANTAGONIST-COATED ELECTRODE AND USES THEREOF - The present invention provides an electrode designed for implantation into the central nervous system (CNS) of a mammal, wherein said electrode is substantially coated with interleukin-1 receptor antagonist (IL-1ra) or a coating composition comprising it, and the IL-1ra actively inhibits scarring on or around the surface of the electrode when implanted into the CNS. The electrode of the invention may be used for brain recording and/or stimulation, and can thus be used for treatment of a brain dysfunction, a brain disease or disorder, or a brain injury, as well as for brain computer interface, brain machine interface, or electrotherapy. | 2014-09-04 |
20140249397 | DIFFERENTIAL NON-CONTACT BIOPOTENTIAL SENSOR - A differential non-contact sensor system for measuring biopotential signals is described. The sensor is a low-noise, non-contact capacitive sensor system to measure electrical voltage signals generated by the body comprising two capacitive electrodes and outputting a differential signal. | 2014-09-04 |
20140249398 | DETERMINING PULSE TRANSIT TIME NON-INVASIVELY USING HANDHELD DEVICES - A system and method to determine pulse transit time using a handheld device. The method includes generating an electrocardiogram (EKG) for a user of the handheld device. Two portions of the user's body are in contact with two contact points of the handheld device. The method also includes de-noising the EKG to identify a start time when a blood pulse leaves a heart of the user. The method further includes de-noising a plurality of video images of the user to identify a pressure wave indicating an arterial site and a time when the pressure wave appears. Additionally, the method includes determining the PTT based on the de-noised EKG and the de-noised video images. | 2014-09-04 |
20140249399 | Determining Functional Severity of Stenosis - A method for determining functional severity of a stenosis includes: (a) generating a simulated perfusion map from a calculated blood flow; (b) comparing the simulated perfusion map to a measured perfusion map to identify a degree of mismatch therebetween, the measured perfusion map representing perfusion in a patient; (c) modifying a parameter in a model used in calculating the blood flow when the degree of mismatch meets or exceeds a predefined threshold; (d) computing a hemodynamic quantity from the simulated perfusion map when the degree of mismatch is less than the predefined threshold, the hemodynamic quantity being indicative of the functional severity of the stenosis; and (e) displaying the hemodynamic quantity. Systems for determining functional severity of a stenosis are described. | 2014-09-04 |
20140249400 | DIAGNOSTIC SYSTEM FOR DETECTION OF FLUID CHANGES - A diagnostic system for monitoring changes in a medium is disclosed. The system includes a transmitter configured to generate and transmit a time-varying magnetic field into a medium responsive to a first signal. The system also includes a receiver positioned on an opposite side of the medium from the transmitter and configured to generate a second signal responsive to a received magnetic field at the receiver. The system also includes a processing unit configured to determine a phase shift between the transmitted magnetic field and the received magnetic field for a plurality of frequencies of the transmitted time-varying magnetic field. | 2014-09-04 |
20140249401 | APPARATUS AND METHOD FOR MR EXAMINATION, AND TEMPERATURE CONTROL SYSTEM AND METHOD - The invention provides an apparatus ( | 2014-09-04 |
20140249402 | RADIOACTIVE EMISSION DETECTOR EQUIPPED WITH A POSITION TRACKING SYSTEM - A radioactive emission probe in communication with a position tracking system and the use thereof in a variety of systems and methods of medical imaging and procedures, are provided. Specifically, wide-aperture collimation-deconvolution algorithms are provided, for obtaining a high-efficiency, high resolution image of a radioactivity emitting source, by scanning the radioactivity emitting source with a probe of a wide-aperture collimator, and at the same time, monitoring the position of the radioactive emission probe, at very fine time intervals, to obtain the equivalence of fine-aperture collimation. The blurring effect of the wide aperture is then corrected mathematically. Furthermore, an imaging method by depth calculations is provided, based on the attenuation of photons of different energies, which are emitted from the same source, coupled with position monitoring. | 2014-09-04 |
20140249403 | SELF-ASSEMBLED, MICROPATTERNED, AND RADIO FREQUENCY (RF) SHIELDED BIOCONTAINERS AND THEIR USES FOR REMOTE SPATIALLY CONTROLLED CHEMICAL DELIVERY - The present invention relates to a nanoscale or microscale particle for encapsulation and delivery of materials or substances, including, but not limited to, cells, drugs, tissue, gels and polymers contained within the particle, with subsequent release of the therapeutic materials in situ, methods of fabricating the particle by folding a 2D precursor into the 3D particle, and the use of the particle in in-vivo or in-vitro applications. The particle can be in any polyhedral shape and its surfaces can have either no perforations or nano/microscale perforations. The particle is coated with a biocompatible metal, e g gold, or polymer e g parvlene, layer and the surfaces and hinges of the particle are made of any metal or polymer combinations. | 2014-09-04 |
20140249404 | VASCULAR BRANCH CHARACTERIZATION - An apparatus and method for characterizing a region of interest (ROI) including measuring position and orientation data within the ROI; and generating a geometric data set to include one or more of: length, bifurcation location, angle and curvature characteristics of the ROI. Also, sequentially taking an image of a tool within the ROI; comparing tool dimensions with ROI dimensions; and estimating diameter, length, take-off angle, and/or tortuosity characteristics based on the comparisons. | 2014-09-04 |
20140249405 | IMAGE SYSTEM FOR PERCUTANEOUS INSTRUMENT GUIDENCE - Hardware and software methodology are described including a synthesized User Interface (UI) to provide guidance for injection and other procedures under medical imaging. The UI provides a practitioner the option of viewing multiple images concurrent with a live image. A guidance image corresponds to correct probe placement for a selected procedure, a reference image corresponds to an expected view with such probe placement in the live image. The reference image may be variously labeled. Another option involves probe tracking to update the guidance and/or reference image view(s). | 2014-09-04 |
20140249406 | COMPENSATOR-BASED BRACHYTHERAPY - Compensator-based brachytherapy (CBT) for treatment of cancerous tumors or other pathologic tissues. CBT permits, in one aspect, increased dosage conformity for non-radially symmetric tumors by utilizing a device that can shield radiation emanated from an electronic brachytherapy (BT) source or non-electronic BT source. The device can comprise, in one aspect, a radiation compensator having a treated surface that comprises a position-dependent thickness based at least on a radiation therapy plan specific to a patient and geometry of a patient region to be treated. In an additional or alternative aspect, the device can comprise a source of radiation movably inserted into an enclosure coupled to the radiation compensator. As part of CBT, in one implementation, the radiation source can reside at a plurality of locations within the radiator compensator during a respective plurality of dwell times based on the radiation therapy plan. | 2014-09-04 |
20140249407 | Miniature Optical Elements for Fiber-Optic Beam Shaping - In part, the invention relates to optical caps having at least one lensed surface configured to redirect and focus light outside of the cap. The cap is placed over an optical fiber. Optical radiation travels through the fiber and interacts with the optical surface or optical surfaces of the cap, resulting in a beam that is either focused at a distance outside of the cap or substantially collimated. The optical elements such as the elongate caps described herein can be used with various data collection modalities such optical coherence tomography. In part, the invention relates to a lens assembly that includes a micro-lens; a beam director in optical communication with the micro-lens; and a substantially transparent film or cover. The substantially transparent film is capable of bi-directionally transmitting light, and generating a controlled amount of backscatter. The film can surround a portion of the beam director. | 2014-09-04 |
20140249408 | ADAPTIVE DUAL-PASS TARGETED RECONSTRUCTION AND ACQUISITION - A hybrid imaging system includes a first imaging system configured to acquire anatomical data of a first field of view of an anatomical structure. A second imaging system configured to acquire functional data of the anatomical structure, the second imaging system acquiring functional data in a two-pass list-mode acquisition scheme. A reconstruction processor configured to reconstruct the functional data based on attenuation data into an attenuation corrected image and reconstruct the anatomical data into one or more high resolution images of one or more regions of interest. | 2014-09-04 |
20140249409 | Lead Electrode Marking System and Method for Deployment - A lead includes a lead body having at least two electrodes and a lead marker. The lead marker corresponds to a size and spacing of each of the at least two electrodes. The spacing between the electrodes and lead marker corresponds to an operative length of a first lead introducer configured to be used with the lead. Lead systems that include one or more lead introducers and kits including the same are also disclosed. | 2014-09-04 |
20140249410 | INFORMATION SENSING SYRINGE - Syringe systems and flow control systems configured to detect information associated with a liquid material are described. The syringe systems may include a syringe body for housing the liquid material and an injector piston for expelling the liquid material out of the syringe through a discharge outlet at a distal end of the syringe body. Components of the syringe, such as an injector piston, may include sensors configured to measure and/or detect a property of the liquid material, such as concentration, pH, or radioactivity. The flow control system may include a pinch valve and a platen arranged about a fluid delivery channel. Flow within the fluid delivery channel may be controlled by increasing (squeezing the fluid delivery channel) or decreasing the distance between the pinch valve and the platen. Components of the flow control system may include detectors configured to detect properties of fluid in the fluid control channel. | 2014-09-04 |
20140249411 | TRI-RING SYRINGE - A tri-ring syringe comprising: a barrel ( | 2014-09-04 |
20140249412 | NJECTOR HEAD WITH ROTATION MECHANISM - An injector head with rotation mechanism allows selection between a state in which a syringe assumes a priming orientation with a through hole of the syringe positioned upper than the injector head body, and a state in which the syringe assumes a contrast agent injectable orientation with the through hole of the syringe positioned lower than the injector head body. | 2014-09-04 |
20140249413 | THERANOSIS OF MACROPHAGE-ASSOCIATED DISEASES WITH ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES (USPIO) - Macrophages sequester and aggregate ultrasmall superparamagnetic iron oxide nanoparticles (USPIO) in their lysosomes. The amount of USPIO loading of macrophages depends upon the route and dose of administration, and the pharmacokinetics of accumulation and removal. Both fixed macrophages and activated macrophages associated with inflammatory diseases and cancer phagocytize USPIOs, and the loaded macrophages can serve to identify the extent of a macrophage-dependent disease as well as to direct treatment options. Furthermore, the absorption of energy from incident electromagnetic waves by the aggregated nanoparticles can be used for conformal thermotherapy. The USPIOs can further be used to carry drugs to the same activated macrophages. The co-administered drugs can be bound to the USPIO by condition-dependent releasing links that are responsive to local pH or heating. | 2014-09-04 |
20140249414 | System and Method for Mixed Modality Acoustic Sampling - Systems and methods for relaying electrical signals representing acoustic response of a volume of tissue to light and ultrasound stimulation. In an embodiment, a plurality of ultrasound transducers receive acoustic energy from the volume and generate electrical energy, which is transmitted via an electrical path to a relay system. The ultrasound transducers are operated at a wide band frequency of at least 1 MHz to 5 MHz to receive acoustic energy from the volume of tissue responsive to light stimulation and at a narrower band frequency to receive acoustic energy from the volume of tissue responsive to acoustic stimulation. The relay system relays the electrical signals to an optoacoustic system or an ultrasound instrument for further processing depending on whether the electrical signals resulted from ultrasound or light stimulation. In an embodiment, optoacoustic, ultrasound, or other images are generated from the electrical signals and may be coregistered, overlayed, or displayed. | 2014-09-04 |
20140249415 | METHOD FOR DETERMINING, IN REAL TIME, THE PROBABILITY THAT TARGET BIOLOGICAL TISSUE IS OPPOSITE AN ULTRASONIC TRANSDUCER - A method for determining, in real time, the probability that target biological tissue is opposite an ultrasonic transducer, the method including: transmitting, via an ultrasonic transducer, an ultrasonic signal into biological tissue; the ultrasonic transducer receiving the transmitted ultrasonic signal which has been backscattered by the biological tissue; calculating at least two instantaneous parameters of the backscattered ultrasonic signal; calculating a predictive value of the presence of an acoustic signature of target biological tissue, the predictive value being calculated via a statistical law using the at least two calculated instantaneous parameters; estimating the probability that the target biological tissue is opposite the ultrasonic transducer, the estimation depending on the calculated predictive value and/or on at least one strength condition based on at least one of the two calculated instantaneous parameters. | 2014-09-04 |
20140249416 | PULSE OFFSET ULTRASONIC IMAGING - A diagnostic ultrasound image of a region of interest (ROI) of a body is formed by transmitting into the ROI at least a first and a second ultrasound pulse, in which the second pulse is phase-shifted relative to the first pulse by an amount other than 0 or a multiple of 180 degrees. Discretized receive signals from the pulses are interleaved to form a resultant operating signal that is detected and beamformed as the operating signal. | 2014-09-04 |
20140249417 | ULTRASOUND DIAGNOSTIC DEVICE AND ULTRASOUND DIAGNOSTIC DEVICE CONTROL METHOD - An ultrasound diagnostic device to which an ultrasound probe is connectable, measuring an IMT of a vascular wall in a carotid artery, including: a transmission unit supplying a transmission signal to the probe for causing ultrasound transmission along a longitudinal cross-section of the carotid artery; a reception unit receiving a signal based on a reflected ultrasound received by the probe, and generating a reception signal; a vascular feature calculation unit extracting position information from the reception signal, including at least one of: piece positions for vascular wall pieces; and a relative relationship between piece positions, and detecting a boundary between a CCA and a CCA bulb according to variation in the position information with respect to the longitudinal direction of the carotid artery; a ROI determination unit determining a ROI defining an IMT measurement range with respect to the boundary; and an IMT measurement unit measuring the IMT. | 2014-09-04 |
20140249418 | ULTRASOUND DIAGNOSTIC IMAGING APPARATUS - Disclosed is an ultrasound diagnostic imaging apparatus including an ultrasound probe which outputs transmission ultrasound toward a subject due to a pulse signal being input and which outputs a received signal by receiving reflected ultrasound from the subject, and a transmission unit which makes the ultrasound probe generate the transmission ultrasound by outputting a pulse signal whose drive waveform is formed of rectangular waves. The frequency power spectrum of the pulse signal has intensity peaks in a frequency band included in a transmission frequency band at −20 dB of the ultrasound probe on a low frequency side and a high frequency side of a center frequency of the transmission frequency band, respectively, and intensity of a frequency region between the intensity peaks is −20 dB or greater with a maximum value of intensity among the intensity peaks being a reference. | 2014-09-04 |
20140249419 | METHOD FOR MANUFACTURING ULTRASOUND PROBE AND ULTRASOUND DIAGNOSTIC IMAGING APPARATUS - A method for manufacturing an ultrasound probe which includes a piezoelectric element for transmitting and receiving ultrasound waves and an acoustic matching layer provided by lamination of two or more matching materials on a front surface of the piezoelectric element, the method including forming at least one of the two or more matching materials from a thermosetting resin and a filler for adjusting an acoustic impedance; and bonding the two or more matching materials with an adhesive having a viscosity of 10 Pa·s or less at 25° C. | 2014-09-04 |
20140249420 | ULTRASOUND DIAGNOSTIC APPARATUS - An ultrasound diagnostic apparatus includes a signal generation unit, amplitude adjustment units and a control unit. The signal generation unit generates a pulse signal with a predetermined voltage amplitude. The amplitude adjustment units individually change the voltage amplitude of the pulse signal so as to output pulse signals with individual voltage amplitudes to their respective transducers. The control unit controls change amounts of the voltage amplitude made by the amplitude adjustment units. Each amplitude adjustment unit includes resistive elements and switching units which change a conductive state of their respective resistive elements. The control unit outputs a control signal to set a combination of ON and/or OFF of the switching units to change a load of the amplitude adjustment unit so as to apply to the transducer a voltage for an amplitude of ultrasound which is transmitted from each of the transducers. | 2014-09-04 |