37th week of 2014 patent applcation highlights part 50 |
Patent application number | Title | Published |
20140255461 | Decorin and Gliosis and Related System and Method - Brain stimulators are used to treat a variety of disorders, and their range of uses continues expand. However, one problem with long-term stimulation of neural tissue is the need to increase the stimulation parameters to continue to maintain the same clinical effect. This is thought to be due to local tissue reaction to the implanted foreign body. Because the implanted stimulator functions by means of contact with functional cells within the tissue, prevention of tissue reaction to the stimulator would make a significant improvement to the device's performance and longevity. | 2014-09-11 |
20140255462 | Xenotransplant Compositions and Methods of Stroke Therapy - Disclosed are implant compositions and methods for treatment of neurological diseases of the central nervous system of a mammal. | 2014-09-11 |
20140255463 | SWEET TART ENERGY TABLET - An energy tablet and method of manufacturing the same that successfully masks the bitter taste of caffeine which has precluded popularity of chewable energy tablets in the past. | 2014-09-11 |
20140255464 | MULTI-LAYER BIODEGRADABLE DEVICE HAVING ADJUSTABLE DRUG RELEASE PROFILE - Methods and apparatus for a biodegradable multi-layer device suitable for medical applications are provided, wherein the device is formed from multiple film-layers configured to have different characteristics from one another such as different release profiles for therapeutic agents, adhesive properties, stiffness properties, and solubility properties. The film-layers may include a solid fibrinogen component. A device having multiple film-layers may take a non-adherent form during delivery to a target location within or on tissue, and thereafter may be exposed to moisture to take an adherent form on the tissue. The device may include a number of additives, including materials to improve the mechanical properties of the device, or one or more therapeutic or contrast agents. | 2014-09-11 |
20140255465 | Process For The Preparation Of A Non-Corrosive Base Solution And Methods Of Using Same - The present invention provides novel methods of making a non-corrosive base solution for use as an alkalinity increasing agent and/or antioxidant. The present invention further provides novel compositions and methods which can be used to provide relief from acidosis, acidemia, and disorders related to or complicated by acidosis or excessive free radical or other reactive oxygen species production in mammalian subjects. | 2014-09-11 |
20140255466 | COMPOSITION FOR ENHANCING TRANSDERMAL ABSORPTION OF DRUG AND PATCH PREPARATION - The present invention relates to a composition for enhancing transdermal absorption of a drug, containing a polyvalent alcohol having 3 to 8 carbon atoms, an organic acid having 2 to 20 carbon atoms, and a higher alcohol having 12 to 20 carbon atoms, and a patch preparation containing a support and a drug-containing adhesive layer containing the composition on one surface of the support. | 2014-09-11 |
20140255467 | MODIFIED POLYNUCLEOTIDES ENCODING CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4 - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 2014-09-11 |
20140255468 | MODIFIED POLYNUCLEOTIDES ENCODING PROGRAMMED CELL DEATH 1 - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 2014-09-11 |
20140255469 | USE OF PHOTOLYASE FOR REDUCING OR IMPROVING SUBCLINICAL FIELD CANCERIZATION ASSOCIATED WITH ACTINIC KERATOSIS - The present invention relates to the use of photolyase enzymes to reduce or improve subclinical skin field cancerization associated with actinic keratosis or non-melanoma skin cancer (NMSC) and methods for the therapeutic treatment of subclinical field cancerization associated with actinic keratosis and/or non-melanoma skin cancer (NMSC). | 2014-09-11 |
20140255470 | MULTIVALENT LIPOSOME FORMULATIONS - This disclosure provides compositions, kits, and methods useful for treating or preventing viral and bacterial infection and reducing or preventing the effects of toxins. The methods comprise administering to a subject an effective amount of a liposomal composition. | 2014-09-11 |
20140255471 | METHOD OF TREATING BRAIN TUMORS - Provided herein are methods useful for treating a brain tumor in a subject in need thereof, comprising administering to said subject an active agent comprising poly-FdUMP or a pharmaceutically acceptable salt thereof. Also provided are compositions comprising poly-FdUMP and one or more additional active agents useful for treating a brain tumor. | 2014-09-11 |
20140255472 | PEGYLATED LIPOSOMES FOR DELIVERY OF IMMUNOGEN-ENCODING RNA - The invention provides a liposome having a lipid bilayer encapsulating an aqueous core, wherein: (i) the lipid bilayer comprises at least one lipid which includes a polyethylene glycol moiety, such that polyethylene glycol is present on the liposome's exterior, wherein the average molecular mass of the polyethylene glycol is above 3 kDa but less than 11 kDa; and (ii) the aqueous core includes a RNA which encodes an immunogen. These liposomes are suitable for in vivo delivery of the RNA to a vertebrate cell and so they are useful as components in pharmaceutical compositions for immunising subjects against various diseases. | 2014-09-11 |
20140255473 | STEROID HORMONE DELIVERY SYSTEMS AND METHODS OF PREPARING THE SAME - The present invention is directed to steroid hormone delivery systems and methods of preparing the same. In particular, the steroid hormone delivery systems provided include a primary construct having one or more hydrophobic steroid hormone esters in the form of a liposome, a lipid particle, a micelle, an emulsion or a niosome which is then formulated into a secondary construct for administration. Exemplary secondary constructs include a film for sublingual or buccal administration. | 2014-09-11 |
20140255474 | Composition for Treatment of Inflammatory Disorders - A pharmaceutical composition for parenteral administration, comprising liposomes composed of non-charged vesicle-forming lipids, optionally including not more than five (5) mole percent of charged vesicle-forming lipids, the liposomes having a selected mean particle diameter in the size range between about 40-200 nm and containing a water soluble corticosteroid for the site-specific treatment of inflammatory disorders, is provided. | 2014-09-11 |
20140255475 | METHOD OF LYOPHILIZING LIPOSOMES - Lyophilized liposomal formulations with two or more encapsulated drugs are disclosed. These formulations display superior drug retention profiles and also maintain size distribution following lyophilization and reconstitution. | 2014-09-11 |
20140255476 | COMPOSITIONS, DEVICES, AND METHODS FOR TREATING INFECTIONS - Compositions, devices, and methods for treating infections. | 2014-09-11 |
20140255477 | Compositions and Methods for Delivery of High-Affinity Oxygen Binding Agents to Tumors - While tumor hypoxia is recognized as a key barrier to effective chemo and radiation therapy of solid tumor malignancies, and an important biological mediator of more aggressive tumor phenotype and behavior for over 50 years, prior attempts to improve tumor oxygenation have relied on increasing the total amount of oxygen bound to each molecule of natural hemoglobin (e.g. through hyperbaric oxygen treatments), increasing the ease of release of oxygen from hemoglobin (through the introduction of exogenous allosteric small molecules), or increasing the total amount of oxygen in the body by injecting perfluorocarbon emulsions, or polymerized or pegylated compositions of natural human or bovine hemoglobin. The embodiments provide a novel approach of introducing into the vascular system agents that possess inherently higher-affinities for molecular oxygen that that of natural human hemoglobin, and coupling these agents with inert carriers that shield them from unwanted biological interactions within the body. | 2014-09-11 |
20140255478 | Hair styling compositions - Hair styling compositions include at least one volatile compound and a hair fixative co-polymer, in which the hair fixative co-polymer includes at least one first monomer having an acid containing group and at least one second monomer having a hydrophobic group. The hair styling compositions provide extended release of volatile compounds, such as fragrances. | 2014-09-11 |
20140255479 | Pharmaceuticals for Oral Delivery - The present invention provides pharmaceutical compositions suitable for oral and methods of treating subjects in need thereof. The pharmaceutical compositions of the present invention enhance bioavailability of at least one compound classified as BCS Class II, BCS Class III or BCS Class IV. | 2014-09-11 |
20140255480 | PHARMACEUTICAL FORMULATION OF NANONIZED FENOFIBRATE - The invention relates to a pharmaceutical formulation of nanonised fenofibrate, to a method for preparing same, and to the uses thereof. | 2014-09-11 |
20140255481 | Pharmaceutical Compositions for Oral Administration of Insulin Peptides - The invention is related to pharmaceutical compositions suitable for oral administration of insulin peptides, methods of making such and treatment with such. | 2014-09-11 |
20140255482 | Manufacturing Solid Pharmaceutical Dosage Forms With Visible Micro- And Nanostructured Surfaces And Micro- And Nanostructured Pharmaceutical Dosage Form - A solid pharmaceutical dosage form [ | 2014-09-11 |
20140255483 | PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition. | 2014-09-11 |
20140255484 | MODIFIED RELEASE PHARMACEUTICAL COMPOSITIONS OF DEXLANSOPRAZOLE - Modified release oral pharmaceutical compositions of dexlansoprazole or pharmaceutically acceptable salts or hydrated forms thereof in the form of a bilayer tablet and processes for the manufacture of the tablet composition and its use in the treatment of gastrointestinal disorders. | 2014-09-11 |
20140255485 | COLLAGEN HYDROLYSATE AND USE THEREOF - The present invention relates to collagen hydrolysate and the use thereof for treating and/or preventing cellulite. | 2014-09-11 |
20140255486 | Coated Tablet Formulation and Method - A coated tablet formulation is provided which includes a medicament such as the DPP4-inhibitor, saxaglipitin | 2014-09-11 |
20140255487 | DOSAGE FORM FOR INSERTION INTO THE MOUTH - Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract. | 2014-09-11 |
20140255488 | LONG ACTING SUSTAINED-RELEASE FORMULATION CONTAINING DOPAMINE RECEPTOR AGONIST AND THE PREPARATION METHOD THEREOF - The present invention relates to a long-acting sustained-release dosage form for treatment of Parkinson Disease, comprising a dopamine receptor agonist and a pharmaceutically acceptable biodegradable polymer accessories, wherein the content of the dopamine receptor agonist in the sustained-release dosage form is 5-50% by weight, and the content of the pharmaceutically acceptable polymer accessories is 50-95% by weight. | 2014-09-11 |
20140255489 | CONSISTENT CALCIUM CONTENT BONE ALLOGRAFT SYSTEMS AND METHODS - Embodiments of the present invention provides bone graft compositions, and methods for their use and manufacture. A bone graft composition may include a first amount of non-demineralized cancellous bone. The composition may further include a second amount of demineralized cancellous bone. The composition may also include a third amount of demineralized cortical bone. The non-demineralized cancellous bone, the demineralized cancellous bone, and the demineralized cortical bone may be obtained from the same cadaveric donor. | 2014-09-11 |
20140255490 | PARTICULARLY STORAGE-STABLE AND THIXOTROPICALLY STABLE PROPHYLAXIS PASTE FOR PROFESSIONAL DENTAL USE - The invention relates to a particularly storage-stable and thixotropically stable dental prophylaxis paste for professional tooth cleaning which is very easy to use and thoroughly cleans and polishes the teeth of the patient and causes little abrasion of natural tooth substance. Such a dental prophylaxis paste may comprise:
| 2014-09-11 |
20140255491 | Method and System For the Treatment of Chronic Obstructive Pulmonary Disease With Nebulized Anticholinergic Administrations - Inhalation solutions for administration of muscarinic antagonists for the treatment of breathing disorders, such as COPD, are provided. | 2014-09-11 |
20140255492 | FINE DRY PARTICULATE ADENOSINE COMPOSITIONS AND TOPICAL FORMULATIONS INCLUDING THE SAME - Fine dry particulate adenosine compositions suitable for use in topical formulations, as well as methods of making the same, are provided. In the dry particulate adenosine composition, the adenosine active agent is associated with the particles, e.g., via entrapment in the pores of the particles and/or ionic binding and/or non-covalent binding to the surface of the particles and/or loosely associated with the particles. Also provided are topical formulations which include the dry particulate adenosine compositions of the invention, and methods of using the same. | 2014-09-11 |
20140255493 | EXTRUDATE AND METHODS OF USING SAID EXTRUDATE - The invention relates to a method for the preparation of a silicic acid comprising extrudate, comprising the steps of: i) forming of stabilised silicic acid, by hydrolysing a silicon compound into orthosilicic acid and/or oligomers thereof in the presence of a stabilizing agent, which is a quaternary ammonium compound, or an amino-acid, or an amino acid source or combinations thereof; ii) mixing of the stabilised silicic acid with a carrier in an amount up to the loading capacity of the carrier for silicic acid; and iii) extruding the resulting mixture thereby forming the extrudate, to extrudates obtainable with the method, to an extrudate for use in the production of animal feed, feed supplement, human food and/or food supplement and of a pharmaceutical or cosmetic preparation, and for the treatment of infections, nails, hair, skin, teeth, collagen, connective tissue, bones, osteopenia, cell generation and degenerative (ageing) processes, and to a pharmaceutical composition comprising an extrudate. | 2014-09-11 |
20140255494 | Novel Formulation of Indomethacin - The present invention relates to methods for producing particles of indomethacin using dry milling processes as well as compositions comprising indomethacin, medicaments produced using indomethacin in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of indomethacin administered by way of said medicaments. | 2014-09-11 |
20140255495 | COLON LAVAGE SYSTEM - The present invention provides compositions, systems, kits, and methods for preparation prior to a colonoscopy or other gastrointestinal procedure. In particular, the present invention provides a colon lavage system comprising an aqueous portion and a solid portion. | 2014-09-11 |
20140255496 | MICRONIZED PLACENTAL TISSUE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME - Described herein are compositions composed of micronized placental components, extracts of micronized placental components, and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions and the extracts thereof are also described herein. | 2014-09-11 |
20140255497 | Organic Compounds - A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol. | 2014-09-11 |
20140255498 | PHARMACEUTICAL NANOSUSPENSION - The present invention in general relates to a pharmaceutical suspension comprising nano-sized cocrystals of at least one active ingredient and at least one dicarboxylic acid. It in particular relates to a pharmaceutical suspension comprising nano-sized cocrystals of at least one anthelmintic drug and at least one dicarboxylic acid. The invention further relates to uses, methods for use and methods for manufacturing the pharmaceutical suspension according to this invention. | 2014-09-11 |
20140255499 | Method of Forming Fine Particles of a Drug Substance - A method of forming fine particles of a drug substance using a piston-gap high pressure homogeniser. | 2014-09-11 |
20140255500 | METHOD FOR PREPARING GRAPHENE - A method of preparing graphene includes supplying a gas on a metal catalyst, the gas including CO | 2014-09-11 |
20140255501 | Novel Preparation Of An Enteric Release System - Hydrophobic liquids are microencapsulated by an enteric matrix in an environment substantially free of organic solvents, the process including forming an emulsion of the enteric material and hydrophobic liquid in water, the emulsion titrated with an acid to form a particulate precipitate of the microencapsulated hydrophobic liquid in an enteric matrix. | 2014-09-11 |
20140255502 | NANOPARTICLE DRUG CARRIER, PHARMACEUTICAL COMPOSITION AND MANUFACTURING METHOD THEREOF - A pharmaceutical composition is provided. The pharmaceutical composition includes a nanoparticle, a shell and a drug, wherein the nanoparticle has an outer surface and the drug is mixed with the shell and is formed on the outer surface. | 2014-09-11 |
20140255503 | PHARMACEUTICAL COMPOSITION OF OMEPRAZOLE - The present invention refers to oral solid pharmaceutical compositions comprising concentrate omeprazole pellets, processes for the preparation of the same and their use as medicaments, more particularly for the treatment and/or prophylaxis of a gastrointestinal disorder. | 2014-09-11 |
20140255504 | ENHANCEMENT OF THE EFFICACY OF THERAPEUTIC PROTEINS - A formulation for administration of at least one therapeutic mammalian protein to a mammal or a protein selected from the group, and for enhancing the absorption, distribution and release of the at least one therapeutic mammalian protein in or on the mammal, comprising at least one therapeutic mammalian protein in a micro-emulsion comprising a dispersion of vesicles or microsponges of a fatty acid based component in an aqueous or other pharmacologically acceptable carrier in which nitrous oxide is dissolved, the fatty acid based component comprising at least one long chain fatty acid based substance selected from the group consisting of free fatty acids and derivatives of free fatty acids. A method for effective delivery of at least one therapeutic mammalian protein to a mammal and for enhancing the therapeutic efficacy of such at least one therapeutic mammalian protein, comprising the step of administering the at least one therapeutic mammalian protein to the mammal in such a formulation. | 2014-09-11 |
20140255505 | Pazopanib Formulation - A granulation formulation of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide or pharmaceutically acceptable salt thereof, which is adapted for reconstitution with an aqueous vehicle, and associated oral suspension. | 2014-09-11 |
20140255506 | OSTEOINDUCTIVE DEMINERALIZED CANCELLOUS BONE - An osteoinductive demineralized bone matrix, corresponding osteoimplants, and methods for making the osteoinductive demineralized bone matrix are disclosed. The osteoinductive demineralized bone matrix may be prepared by providing demineralized bone and altering the collagenous structure of the bone. The osteoinductive demineralized bone matrix may also be prepared by providing demineralized bone and compacting the bone, for example via mechanical compaction, grinding into a particulate, or treatment with a chemical. Additives such as growth factors or bioactive agents may be added to the osteoinductive demineralized bone matrix. The osteoinductive demineralized bone matrix may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, may induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. The osteoinductive demineralized bone matrix may also be used as a delivery device to administer bioactive agents. | 2014-09-11 |
20140255507 | METHOD FOR PROMOTING THE SYNTHESIS OF COLLAGEN AND PROTEOGLYCAN IN CHONDROCYTES - The synthesis of collagen and proteoglycan in chondrocytes, such as intervertebral disc cells, articular chondrocytes and meniscal cells is promoted by administration of an extract from inflamed tissue inoculated with vaccinia virus. | 2014-09-11 |
20140255508 | MICRONIZED PLACENTAL TISSUE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME - Described herein are composition composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein. | 2014-09-11 |
20140255509 | COMPOSITION - Compositions and formulations comprising a non-neutralised tocol phosphate and a vitamin A compound, which are suitable for the treatment of inflammation and/or infection in breast or udder tissue, more particularly in a mammary gland, reducing the somatic cell count in a lactating subject and supplementing vitamin E levels in a subject. | 2014-09-11 |
20140255510 | PEROXYCARBOXYLIC ACID COMPOSITIONS SUITABLE FOR INLINE OPTICAL OR CONDUCTIVITY MONITORING - Peracid stable fluorescent active compounds in highly acidic, equilibrium peroxycarboxylic acid sanitizing compositions are disclosed as having improved fluorescent stability allowing for monitoring of peroxycarboxylic acid concentration by conductivity and/or optical sensors. Beneficially, the compositions are also low odor and low/no VOC dual functioning acid wash and sanitizing compositions. | 2014-09-11 |
20140255511 | ACCELERATING MUSCLE RECOVERY AFTER IMMOBILIZATION-INDUCED MUSCLE ATROPHY - The present invention generally relates to the field of medical nutrition. For example, the present invention provides a composition that can be used to treat, prevent and/or reverse muscle atrophy related to immobilization and its consequences. One embodiment of the present invention concerns a composition comprising a leucine and antioxidants that can be used in accelerating muscle recovery after muscle atrophy. | 2014-09-11 |
20140255512 | COMPOSITION USEFUL FOR THE PREVENTION OR REDUCTION OF THE PROGRESSION OF PROSTATE CANCER - It is described a composition comprising as active ingredients green tea extract and pomegranate extract for the prevention or reduction of the progression of prostate cancer. | 2014-09-11 |
20140255513 | LYTIC DOMAIN FUSION CONSTRUCTS AND METHODS OF MAKING AND USING SAME - The invention relates to fusion constructs, methods of using fusion constructs and methods of treating undesirable or aberrant cell proliferation or hyperproliferative disorders, such as tumors, cancers, neoplasia and malignancies. | 2014-09-11 |
20140255514 | DEFOAMER USEFUL IN A PERACID COMPOSITION WITH ANIONIC SURFACTANTS - Low foaming, highly acidic peroxycarboxylic acid sanitizing compositions are disclosed as having both improved antimicrobial efficacy in comparison to conventional peroxyoctanoic acid and peroxyacetic acid compositions for sanitizing applications. The compositions include a combination of a low-foaming surfactant and an aluminum sulfate (or other metal salt) defoaming agent that is compatible with the highly acidic peroxycarboxylic acid sanitizing compositions. In particular, the sanitizing peroxycarboxylic acid compositions are also low odor and low/no VOC dual functioning acid wash and sanitizing compositions. | 2014-09-11 |
20140255515 | LIQUID COMPOSITIONS OF CALCIUM ACETATE - The invention relates to an aqueous liquid composition of calcium acetate, sweetener, and taste masking agent. Also provided is a method for binding phosphorus within the gastrointestinal tract of an individual by administering to the individual an aqueous solution of at least calcium acetate. | 2014-09-11 |
20140255516 | METHOD OF USING PEELABLE FILM-FORMING COMPOSITION - The compositions and methods of this invention relate to peelable film-forming compositions that may be applied to and removed from the skin containing polyvinyl alcohols and adhesion-enhancing polymers. | 2014-09-11 |
20140255517 | MANAGING POST-TRAUMATIC STRESS DISORDER - In certain embodiments, the disclosure relates to methods of treating or preventing posttraumatic stress disorder comprising administering a pharmaceutical composition comprising effective amount of an angiotensin-converting enzyme inhibitor to a subject in need thereof. In certain embodiments, the angiotensin-converting enzyme inhibitor is administered in combination with an angiotensin receptor blocker. | 2014-09-11 |
20140255518 | Treatment and Prevention of Gastrointestinal Syndrome - Compositions comprising a guanylyl cyclase C agonist in an amount effective to protect intestinal tissue against radiation or chemotherapy and methods of using such compositions to prevent GI syndrome in cancer patient undergoing radiation or chemotherapy and in individuals exposed to or susceptible to exposure to radiation are disclosed. | 2014-09-11 |
20140255519 | ELECTROLYTE SUPPLEMENT AND METHOD OF USE - A method of managing dehydration in an animal includes administering a first electrolyte solution having an SID range at or below 25 mEq/l. After administering the first electrolyte solution, the animal's health condition is observed to determine the effect of the first solution. If the animal's health condition has not sufficiently improved, a second solution comprising the first electrolyte solution supplemented with a second electrolyte supplement is administered to the animal wherein the second electrolyte supplement raises the SID of the second solution to at least 50 mEq/l. | 2014-09-11 |
20140255520 | Methods of Using Solutions of Hypobromous Acid and Hypobromite to Treat Poultry in a Chill Tank During Processing to Increase the Weight of the Poultry - Methods for treating poultry to increase the weight of the poultry are disclosed. The methods may be performed in a chill tank or other reservoir and utilize hypobromous acid from either aqueous hydrogen bromide or aqueous sodium bromide and a source of hypochlorite. The methods comprise contacting a poultry carcass with the hypobromous acid-containing water at a pH of about 6.5 to about 10. The methods result in an increase in the weight of the processed poultry products. | 2014-09-11 |
20140255521 | TOPICAL COMPOSITIONS AND METHODS OF TREATMENT OF TOPICAL DISORDERS - A topical composition includes at least one film forming ingredient; at least one surfactant; at least one non-polar volatile siloxane solvent; at least 15% (w/w) water; and a therapeutically effective concentration of at least one pharmaceutical agent, wherein the composition is sufficiently designed to dry within 60 seconds after application to a body surface to form a dried composition, and wherein the dried composition forms: a flexible film, wherein the flexible film closely follows irregularities of the body surface as well as movement of the body surface, and (ii) a durable film, wherein the durable film does not crack or flake off and remains intact for more than 12 hours giving release of the pharmaceutical agent for an extended period of time. | 2014-09-11 |
20140255522 | TOPICAL COMPOSITIONS AND METHODS OF TREATMENT OF ANORECTAL AND GENITAL DISORDERS - A topical anorectal or genital composition includes at least one film forming ingredient; at least one surfactant; at least one non-polar volatile siloxane solvent; at least 15% (w/w) water, and a therapeutically effective concentration of at least one pharmaceutical agent, wherein the composition is sufficiently designed to dry within 60 seconds after application to the anorectal or genital surface to form a dried composition, and wherein the dried composition forms: a flexible film, wherein the flexible film closely follows irregularities of the body surface as well as movement of the body surface, and (ii) a durable film, wherein the durable film does not crack or flake off and remains intact for more than 12 hours giving release of the pharmaceutical agent for an extended period of time. | 2014-09-11 |
20140255523 | Use of Tiliacora Triandra in Cosmetics and Compositions Thereof - The present disclosure relates to compositions for treating, preventing and improving the condition and aesthetic appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, where the compositions include natural plant constituents which increase expression levels genes, collagen replacement and retention, and cell proliferation of epidermis and dermis associated with the dermatological signs of aging. The compositions of the invention are topically applied to the skin, or are delivered by directed means to a site in need thereof, once daily in an amount effective in improving the condition and aesthetic appearance of skin. | 2014-09-11 |
20140255524 | ALPHA-GPC DIETARY SUPPLEMENTS FOR WEIGHT LOSS AND/OR INCREASING OR MAINTAINING LEAN BODY MASS - Disclosed herein are methods for weight loss and/or maintaining weight and/or increasing and/or maintaining lean body mass using glycerylphosphorylcholine (alpha-GPC). Disclosed herein are formulations of glycerylphosphorylcholine (alpha-GPC) useful for weight loss, and/or maintaining weight and/or maintaining and/or increasing lean muscle mass. | 2014-09-11 |
20140255525 | Beverages with compositions of vinegar - A composite vinegar infused juice blend includes juice blend, including natural fruit and/or vegetable juices; and vinegar composition, including coconut vinegar; and apple cider vinegar. A beetroot based juice blend includes beet juice, carrot juice, apple juice, and water, with equal parts of coconut vinegar and apple cider vinegar. Orange and carrot, mango and sweet potato based juice blends are disclosed. A sweet composite vinegar infused beverage for alleviation or treatment of flu or cold symptoms includes apple cider vinegar, coconut vinegar, water, organic honey, and peppermint extract. Also disclosed is a method for alleviation or treatment of flu or cold symptoms. | 2014-09-11 |
20140255526 | USE OF A GINSENG EXTRACT TO PREVENT AND TREAT ALOPECIA AREATA - Ginseng extracts as well as preparations such as medicaments, pharmaceuticals and food or dietary supplements for use to treat or prevent alopecia areata in subjects requiring such treatment or prevention are provided. The ginseng extract is a carbohydrate extract that contains between about | 2014-09-11 |
20140255527 | Expression Promoting Agent For Clock Gene And Hyaluronic Acid Synthase Gene - A method for promoting expression of a clock gene and/or a hyaluronic acid synthase gene in skin, comprising applying onto skin a composition comprising one kind or two kinds selected from lavender oil and eucalyptus oil, and an alkylene oxide derivative. | 2014-09-11 |
20140255529 | METHOD FOR PREVENTING AND TREATING THROMBOTIC DISORDERS USING A PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF LINDERA OBTUSILOBA - A method for preventing and treating thrombotic disorders in a subject in need thereof comprising, administering a pharmaceutical composition comprising an extract of | 2014-09-11 |
20140255530 | Alternative Pressure Control for an Injection Molding Apparatus - A melt pressure regulating mechanism for an injection molding apparatus having a melt holder for pressurizing molten plastic prior to injection into a mold, the molten plastic having a melt pressure, and an injection element for advancing the molten plastic from the melt holder through a nozzle and into the mold, the melt pressure regulating mechanism comprising a pressure regulating device, comprising at least one of a fluid pressure regulating valve and a pressure relief valve. | 2014-09-11 |
20140255531 | METHOD OF ESTIMATING LIFE OF GEAR PUMP AND RUBBER EXTRUSION APPARATUS - A method of estimating a life of a gear pump includes detecting the number of rotations of a gear and a discharge amount of rubber being extruded from the gear pump; calculating, based on the number of rotations and the discharge amount of the rubber which are detected, a discharge efficiency η (=T1/T) that is a ratio of a measured value T1 of a discharge amount of the rubber that is extruded from the gear pump per one rotation of the gear to a theoretical value T; and estimating the life of the gear pump based on the calculated discharge efficiency η. | 2014-09-11 |
20140255532 | PRESS DIE - A press die is provided which includes a lower die having a lower core and an upper die having an upper core, the upper die includes moving blocks installed movably in a first horizontal direction and a bending shaft installed to the moving blocks, and the bending shaft presses a plate against a side surface forming portion of the lower core as the moving blocks move in the first horizontal direction, thereby enabling the plate to be deformed in the first direction. | 2014-09-11 |
20140255533 | BLOW MOLD UNIT AND BLOW MOLDING MACHINE USING SAME - A blow mold unit including a blow mold including first and second blow cavity split molds and a plurality of raised bottom molds, first and second pressure receiving plates, a first fixing plate to which the first blow cavity split mold and the first pressure receiving plate are fixed, a second fixing plate to which the second blow cavity split mold and the second pressure receiving plate are fixed, a third fixing plate interposed between the first and second fixing plates and to which the plurality of raised bottom molds are fixed at a first surface thereof, a shaft portion extending vertically from a second surface of the third fixing plate, an elevation guide block fixed to one of the first and second fixing plates and elevation guiding the shaft portion, and an elevating rod extending vertically from the second surface. There is also a blow molding machine which includes the blow mold unit. | 2014-09-11 |
20140255534 | REPROGRAMMABLE SHAPE CHANGE SHEET, USES OF THE SHEET AND METHOD OF PRODUCING A SHAPED SURFACE - The invention relates to a reprogrammable shape change sheet, a method of shaping a surface and a reprogrammable injection molding machine. The sheet comprises a plurality of muscle elements capable of changing shape upon electric stimulation, the elements being arranged in an array to define a surface. According to the invention, the muscle elements comprise two muscle material layers capable of changing shape upon electric stimulation and a flexible wiring layer sandwiched between the muscle material layers, the wiring layer being electrically connected to said muscle material layers for delivering electric stimulation signals to the muscle material layers for changing the shape of the muscle elements and further the topology of the surface. The invention provides a new shape change sheet structure, which can be made thin, accurate and durable for various uses. | 2014-09-11 |
20140255535 | VALVE ASSEMBLY FOR INJECTION MOLDING MACHINE - A valve assembly for use with a part handling assembly of an injection molding machine includes a housing having a first tooling port for fluid communication with a first set of receivers on the part handling apparatus and a second tooling port for fluid communication with a second set of receivers on the part handling apparatus. First and second vacuum channels extend through the housing and are provided with respective first and second vacuum closure members to provide selective fluid communication between a vacuum source and the first and second tooling ports, respectively. First and second pressure channels extend through the housing and are provided with respective first and second pressure closure members to provide selective fluid communication between a pressurized fluid source and the first and second tooling ports, respectively. The first pressure closure member is moveable independently from the first vacuum closure member, and the second pressure closure member is moveable independently from the second vacuum closure member. | 2014-09-11 |
20140255536 | INJECTION APPARATUS - An injection apparatus includes a pressure accumulating portion, which is connected to an injection cylinder, and a speed reduction mechanism, which reduces the speed of the injection cylinder arranged in the injection apparatus. The speed reduction mechanism includes an actuating member, which moves integrally with a rod of an injection cylinder rod, and a restriction member, which is arranged in a flow passage for draining or supplying hydraulic oil from or to the injection cylinder, and variably narrows the flow passage in conjunction with movement of the actuating member. | 2014-09-11 |
20140255537 | Nutritional Compositions Containing an Enriched Lipid Fraction and Uses Thereof - The present disclosure relates to a nutritional composition comprising a fat source that includes an enriched lipid fraction derived from milk. The enriched lipid fraction may contain saturated fatty acids, trans-fatty acids, monounsaturated fatty acids, CLAs, BCFAs, cholesterol, milk fat globule membrane proteins, gangliosides, and mixtures thereof. The enriched lipid fraction may exhibit additive or synergistic beneficial health effects when consumed. The disclosure further relates to methods of providing a nutritional composition comprising an enriched lipid fraction to targeted subjects. | 2014-09-11 |
20140255538 | Nutritional Compositions Containing Structured Fat Globules and Uses Thereof - The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof. Additionally, the disclosure relates to methods of supporting lipid digestion in a pediatric subject by providing a nutritional composition comprising an enriched lipid fraction having structured fat globules that are more accessible to lipases. The chemical composition, size and structure of the fat globules may improve digestion. The disclosed nutritional compositions may provide additive and or/synergistic beneficial health effects. | 2014-09-11 |
20140255539 | Nutritional Compositions Containing Structured Fat Globules and Uses Thereof - The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof. Additionally, the disclosure relates to methods of supporting lipid digestion in a pediatric subject by providing a nutritional composition comprising an enriched lipid fraction having structured fat globules that are more accessible to lipases. The chemical composition, size and structure of the fat globules may improve digestion. The disclosed nutritional compositions may provide additive and or/synergistic beneficial health effects. | 2014-09-11 |
20140255540 | RICE PROTEIN SUPPLEMENT AND METHODS OF USE THEREOF - Some embodiments relate to nutritional supplements comprising rice protein isolate. Some embodiments of the nutritional supplement comprise less than about 90 mg of leucine per gram of rice protein isolate and less than about 50 mg of lysine per gram of rice protein isolate. Some embodiments pertain to methods of using the nutritional supplements described herein to achieve one or more of weight gain, weight maintenance, growth, muscle growth, muscle maintenance, decreased muscle loss, or improved exercise training results. | 2014-09-11 |
20140255541 | Dietary Supplement and Methods of Use Thereof - The present disclosure provides a dietary supplement that includes plant ferritin; and methods of use of such a supplement. | 2014-09-11 |
20140255542 | COMPOSITION AND METHOD FOR REDUCING BLOOD GLUCOSE LEVELS - The present invention relates to a composition and method for reducing blood glucose levels in a mammal, such as canines and humans. The composition includes bran, cinnamon, yeast, gelatin, and optionally, wheat germ oil, octacosanol, and/or flavor. The method includes administering the composition to the mammal and, if the composition lacks wheat germ oil, also administering wheat germ oil to the mammal. | 2014-09-11 |
20140255543 | COMPOSITION FOR USE IN THE PROMOTION OF MAGNESIUM ABSORPTION AND/OR MAGNESIUM RETENTION - The invention discloses a composition comprising a mixture of oligosaccharides, said mixture containing at least one N-acetylated oligosaccharide, at least one sialylated oligosaccharide and at least one neutral oligosaccharide, for use in the promotion magnesium absorption and/or magnesium retention. The composition preferably further comprises at least one long chain polyunsaturated fatty acid and/or at least one probiotic. This composition is particularly adapted for use in infants notably preterm infants. | 2014-09-11 |
20140255544 | USE OF WHEY PROTEIN MICELLES FOR IMPROVING INSULIN PROFILE IN DIABETIC PATIENTS - The present invention relates to whey protein micelles for use in the treatment and/or prevention of a disorder linked to an increase in plasma postprandial insulin and/or plasma postprandial glucagon concentration in a subject. The invention relates also to a non-therapeutic use of whey protein micelles to decrease plasma postprandial insulin and/or glucagon concentration in healthy subjects. | 2014-09-11 |
20140255545 | METHOD INVOLVING CONTACT BETWEEN GRAIN RAW MATERIAL LIQUID AND YEAST, GRAIN RAW MATERIAL LIQUID AND SPARKLING BEVERAGE - A method including bringing a grain raw material liquid into contact with a yeast to effectively improve foam properties of a sparkling beverage, a grain raw material liquid, and a sparkling beverage are provided. The method includes bringing a first grain raw material liquid into contact with a yeast to produce a second grain raw material liquid to be used for production of a sparkling beverage. The yeast may be an inactivated yeast. The method may further include producing the sparkling beverage using the second grain raw material liquid. | 2014-09-11 |
20140255546 | NUTRITIONALLY ENHANCED PASTA - The invention provides for the use of a texture modifying agent added to nutritionally enhanced pasta dough, such as pasta dough with high levels of protein, so that a pasta product can be produced with a quality similar to that of conventional pasta. The texture modifying agent, which preferably includes an enzyme, permits the nutritionally enhanced pasta dough to be extruded in conventional pasta manufacturing equipment and to form a pasta product with a texture similar to typical semolina-based pasta. | 2014-09-11 |
20140255548 | LOW-FAT FERMENTED MILK EXCELLENT IN SAVOR AND PROCESS FOR PRODUCTION THEREOF - The invention aims to provide a process for producing a fermented milk capable of effectively preventing deterioration of the smooth mouth feel and milk flavor originated from the milk fat (hereinafter, the smooth mouth feel and milk flavor are put together referred to as “milk-fat characteristic”) which are lost when the milk fat content of fermented milk is intentionally reduced, without using milk fat substitutes, milk-flavor providing agents or the like but based on an ingenuity on the production process, and the fermented milk obtained as the result in which the milk-fat characteristic is improved and the milk fat content is reduced. | 2014-09-11 |
20140255549 | GRANULATED FEED PHOSPHATE COMPOSITION INCLUDING FEED ENZYMES - A granulated phosphate composition that provides sufficient nutritional value as well as enhanced bioavailability of organic phosphorous present in a main feed ingredient. The granulated phosphate composition includes a phosphate source, such as monocalcium phosphate, mono-dicalcium phosphate, or dicalcium phosphate, and one or more feed enzymes such as phytase. When the phosphate composition is compounded and pelleted with a main feed ingredient into a feed pellet, and consumed by a non-ruminant, the phytase component of the phosphate composition liberates otherwise unavailable phosphorous present in the main feed ingredient. | 2014-09-11 |
20140255550 | Protease Variants - The invention relates to a novel 3D structure encoding a | 2014-09-11 |
20140255551 | NOVEL 1,3-DIACYLGLCEROL (1,3-DAG) FOR HARD FAT APPLICATIONS - The invention provides 1,3-DAGs with melting point ranges of from about 32° C. to about 37° C. for use in a variety of hard fat applications and in particular for the preparation of a cocoa butter substitute for confectionery use. The invention contemplates novel 1,3-DAGs, cocoa butter substitute incorporating such 1,3-DAG compounds, confectionery products and shortenings containing both and methods of making such. | 2014-09-11 |
20140255552 | COATED STABILISED MICROWAVE HEATED FOODS - A food product comprising a substrate of pieces of meat, poultry, fish, vegetable, fruit or dairy food and an aqueous composition coating the substrate provides improved performance, particularly for microwave cooking of reheating of the food product. The aqueous coating composition includes a mixture consisting of by dry weight: | 2014-09-11 |
20140255553 | Edible Pet Chew and Method for Making the Same - An edible pet chew has a member of meat based material. As a first aspect of present invention, the edible pet chew has a chewy sheet of meat based material. As another aspect, the edible pet chew has a meat based material chewy sheet member and additionally an edible material member being wrapped therein. As another aspect, the edible pet chew has an edible material member and additionally a meat based material chewy sheet member being wrapped therein. As another aspect, the edible pet chew has a THREE-DIMENSIONAL-SHAPE meat based material member and additionally an edible material member wrapped therein. As another aspect, the edible pet chew has an edible material member and additionally a THREE-DIMENSIONAL-SHAPE meat based material member wrapped therein. Other aspects of present invention provide a method for making the edible pet chew with the essential member of meat based material chewy sheet member or THREE-DIMENSIONAL-SHAPE member. | 2014-09-11 |
20140255554 | CHEWY FOOD COMPOSITIONS - The invention provides food compositions having a chewy texture and methods for making the chewy food compositions. In one aspect, the food composition includes a moisture content and an Aw sufficient to provide the food composition with a chewy texture. In one aspect, an outer shell having a chewy texture encloses a soft meaty inner filling. The shell can have a moisture content ranging from about 15% to about 24% and an Aw ranging from about 0.7 to about 0.84. | 2014-09-11 |
20140255555 | Solid Food with Surface Coating Layer and Automatic Process and Equipment for Making the Solid Food - An automatic process includes dissolving a sticky coating layer, pouring the sticky coating layer onto a main material, bonding a covering layer onto the sticky coating layer to form a semi-product of a solid food, cooling the semi-product to cool the sticky coating layer, and vibrating the semi-product to drop an overlapping part of the covering layer so as to form a solid food which includes the main material, the sticky coating layer and the covering layer. Thus, the solid food is made in an automated manner to save the working time, to reduce the cost of production, and to increase the working efficiency. In addition, the solid food is made automatically so that the product of the solid food satisfies the standardized requirement, thereby enhancing the quality of production. | 2014-09-11 |
20140255556 | SHELF-STABLE SNACK AND METHOD FOR MAKING SAME - A shelf-stable snack and method for making the same. First a dough is mixed and sheeted to form a sheeted dough. Thereafter, the sheeted dough is cut to form at least one dough piece. Sauce is sprayed upon the dough piece with a textural sprayer. The dough has a moisture content of between about 30 and about 45% by weight and has an average particle size of between 100-500 microns. Then the dough piece is dried to a moisture content of less than 3%. | 2014-09-11 |
20140255557 | Methods of Preparing a Bakery Foodstuff Convenience Food Having Organoleptic Profile Comparable to Conventional Oven Baked Goods and Related Bakery Foodstuffs - The invention includes methods of preparing a consumable on demand, warm bakery foodstuff. The method includes preparing a coating fluid; forming a baked good from a bakery mixture by applying ambient heat, maintaining the baked good within the container for a determinate amount of time at a first temperature, exposing the baked good within the container to microwave energy or to heat for a duration of time sufficient to bring at least the baked good from a second temperature to a final temperature of at least about 100° F., inverting the container to release the baked good through the top area of the container and the coating liquid, wherein upon inversion, the coating liquid forms a coating on the inverted baked good. The baked good and for coating liquid each independently has: an aw of about 0.65 to about 0.95 and a moisture content of about 10% to about 30%. | 2014-09-11 |
20140255558 | FROZEN CONFECTIONERY PRODUCT WITH A PEELABLE GEL COATING AND METHOD FOR MANUFACTURING SAME - The present invention relates to a frozen confectionery product comprising a core consisting of a frozen confection, wherein the core is at least partially coated with a frozen flexible edible gel coating, said gel coating being provided with at least one cutting line allowing to peel-off the gel-coating, characterized in that the gel coating comprises at least two visually distinctive gel layers. The invention also relates to a method for making such a product. | 2014-09-11 |
20140255559 | Confection Piece Shape - A confection is provided having a single arcuate ridge extending substantially the entire length of the piece. Due to this unique feature, either alone or in combination with one or more other topographical features, the confection provides an enhanced sensory attribute as compared to a confection having the same composition and not having the arcuate ridge. | 2014-09-11 |
20140255560 | GAS TRANSMITTING POLYURETHANE ADHESIVE - A two-part, solvent-free laminating adhesive including a Part A that is a liquid mixture of a first polyol and a hydroxyl functional acrylic polymer having a molecular weight of no greater than 15,000 g/mole, and a Part B that is an isocyanate-terminated polyurethane prepolyiner. The adhesive is especially suited for making flexible laminates for use in food packaging. When adhered two polymeric film materials and in cured form, the adhesive provides substantially no contribution to the oxygen barrier properties of the laminate. | 2014-09-11 |
20140255561 | Peelable Absorbent Food Package - The present invention provides a peelable microwavable food package capable of absorbing undesired liquids released from packaged food products during storage, display, or heating, including microwave cooking. The present invention provides a peelably sealed microwavable food package in any packaging format including pouches, flow-wrap, horizontal form fill seal (HFFS), vertical form fill seal (VFFS), gas-flushed, vacuum-packaged, sealed rigid plastic containers and the like. | 2014-09-11 |
20140255562 | EXTRUSION-TYPE FROZEN DESSERT STORAGE CONTAINER FOR PREVENTING UNDESIRED AND FORCED EXTRUSION - An extrusion-type frozen dessert storage container for preventing undesired and forced extrusion of a frozen dessert contained therein, including a container body and a sealing membrane. The container body includes an upper container body, a connection portion and a lower container body which are connected with each other. The upper chamfer cambered surface of the upper container body has at least one convex body. The bottom surface of lower container body is provided with an extrusion opening and the inner wall of the container body defines a storage space communicated with the extrusion opening. The sealing membrane adheres to the bottom surface of the container body and is covered on the extrusion opening. | 2014-09-11 |