37th week of 2014 patent applcation highlights part 55 |
Patent application number | Title | Published |
20140255965 | METHODS, COMPOSITIONS, AND KITS FOR DETECTING PROTEASE ACTIVITY IN COMPLEX SAMPLES - Methods and kits are provided for measuring protease activity in samples such as feed or food samples. The methods include adding a water insoluble substrate with a signal producing group to a feed or food sample containing the protease activity to be measured, incubating the sample in phosphate-free buffer such that the signal is produced, and measuring the amount of protease activity in the sample. The methods do not require separation of the incubation buffer from the feed or food and allow for visual inspection of a colorimetric signal for a semi-quantitative measurement of the in-feed/in-food protease activity. Thus, the assay is advantageous as it can be performed on-site without the use of laboratory equipment. | 2014-09-11 |
20140255966 | Method for Fabricating Stable-Isotope-Labeled Target Peptide Fragment in Mass Spectrometry - An object of the present invention is to provide a method for producing a stable isotope-labeled target peptide fragment in mass spectrometry, which achieves inexpensive and convenient production. As a solution to attain the object, the stable isotope-labeled target peptide fragment in mass spectrometry is produced using a method comprising the steps of: expressing a DNA conjugate in a system having a stable isotope-labeled amino acid to thereby prepare a stable isotope-labeled protein, wherein the DNA conjugate comprises: a tandemly linked DNA in which two or more DNAs encoding one or more types of target peptide fragments are linked in tandem; and a DNA encoding a peptide fragment for concentration measurement; subjecting the stable isotope-labeled protein to fragmentation treatment with trypsin to prepare a stable isotope-labeled peptide fragment for concentration measurement and stable isotope-labeled target peptide fragments; quantifying the stable isotope-labeled peptide fragment for concentration measurement using a liquid chromatograph-tandem mass spectrometer (LC/MS/MS); and calculating the concentration of the stable isotope-labeled target peptide fragment of each type from the quantification value of the stable isotope-labeled peptide fragment for concentration measurement. | 2014-09-11 |
20140255967 | SYSTEM AND METHOD FOR COATING OR IMPREGNATING A STRUCTURE WITH CELLS THAT EXHIBIT AN IN VIVO PHYSIOLOGIC FUNCTION - Systems and methods are provided for coating or impregnating a structure with cells that exhibit an in vivo physiologic function. The system includes a specimen holder for holding the structure and cells, as well as a pressure/flow control system that is fluidly coupled to the specimen holder so as to form a flow loop through which fluid traverses. The pressure/flow control system generates and maintains dynamic fluid pressure and flow conditions within the specimen holder and is capable of independently controlling fluid pressure and flow rate in the specimen holder. | 2014-09-11 |
20140255968 | METHOD FOR FABRICATING A PATTERNED SUBSTRATE FOR A CELL CULTURE, A PATTERNED SUBSTRATE FOR CELL CULTURE, AND A CELL CHIP - The present invention relates to a method for fabricating a patterned substrate for a cell culture, comprising the steps of: (1) preparing a substrate; (2) depositing a plasma polymer layer by using a precursor material on the substrate; (3) placing a shadow mask having a predetermined pattern on the plasma polymer layer; (4) treating the substrate, having the shadow mask placed thereon, with a reactive gas using plasma; and (5) removing the shadow mask from the substrate, and a patterned substrate for the cell culture fabricated thereby. The invention also relates to a method for a cell culture with a pattern, comprising the step of culturing cells on the patterned substrate for the cell culture, and a patterned cell chip, and a method of screening a material having an activity of inducing or promoting angiogenesis using the patterned cell chip. | 2014-09-11 |
20140255969 | REAGENTS AND METHODS FOR USING HUMAN EMBRYONIC STEM CELLS TO EVALUATE TOXICITY OF PHARMACEUTICAL COMPOUNDS AND OTHER CHEMICALS - The invention provides biomarker profiles of cellular metabolites and methods for screening chemical compounds including pharmaceutical agents, lead and candidate drug compounds and other chemicals using human embryonic stem cells (hESC) or lineage-specific cells produced therefrom. The inventive methods are useful for testing toxicity, particularly developmental toxicity and detecting teratogenic effects of such chemical compounds. | 2014-09-11 |
20140255970 | SYNTHETIC MICROFLUIDIC SYSTEMS FOR HYPOXIA - A cell culture device can include: an internal chamber configured for an internal cell culture that has at least one port coupled to a perfusion modulating device capable of modulating perfusion in the internal chamber; at least one fluid channel bordering the internal chamber that is configured for a channel cell culture that has at least one port coupled to a perfusion modulating device capable of modulating perfusion in the fluid channel; and a wall separating the internal chamber and at least one fluid channel having gaps that fluidly couple the internal chamber with the at least one fluid channel, wherein the perfusion modulating device causes reduced fluid flow. The internal chamber can include a first cell type and the at least one fluid channel includes a second cell type. The first cell type has an ischemic zone in the middle, a non-ischemic zone adjacent with the at least one fluid channel, and a border zone between the ischemic zone and non-ischemic zone. In one aspect, the internal chamber and at least one fluid channel are modeled from physiological features. In one aspect, the internal chamber and at least one fluid channel are modeled from idealized features. | 2014-09-11 |
20140255971 | SYNTHETIC MICROFLUIDIC SYSTEMS FOR TUMOR METASTASIS - A method of assaying metastasis can include: providing a device of one of the embodiments; introducing the at least one cancer cell into the at least one internal chamber or at least one fluid channel; and studying metastasis of the at least one cancer cell. Optionally: introducing cancer cells into a first internal chamber; detecting escape of the cancer cell from the first internal chamber into the fluid channel; detecting migration of the cancer cell through the fluid channel; detecting adhesion of the cancer cell to a coating on the fluid channel; detecting invasion of the cancer cell into a second internal chamber from the fluid channel; or visualizing metastasis of the cancer cell with a visualization device. | 2014-09-11 |
20140255972 | METHODS OF MONITORING AND ANALYZING METABOLIC ACTIVITY PROFILES DIAGNOSTIC AND THERAPEUTIC USES OF SAME - A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: | 2014-09-11 |
20140255973 | METHOD FOR DETECTING THE INTERACTION OF AT LEAST ONE ENTITY WITH A DIELECTRIC LAYER - The invention relates to a method of detecting the interaction between at least one entity and a dielectric layer containing different electron levels in the energy band gap of the dielectric layer, the method comprising the following steps: | 2014-09-11 |
20140255974 | Method and Use for the Detection of a Component of Interest in Biological Samples - The present invention relates to a use of bismuth ferrite crystals to detect a part of interest in biological samples. In order to provide a method which is cost-effective and in which a measurement can be carried out with a high degree of accuracy and which is quantifiable, the invention proposed that the part is marked with one or more bismuth ferrite crystals in a biological sample to be examined and the part marked in this manner is detected in the biological sample using at least one magnetic measuring method and at least on one optical measuring method. | 2014-09-11 |
20140255975 | TRANSGENIC PIG MODELS OF CYSTIC FIBROSIS - This invention relates to transgenic pig models of cystic fibrosis, cells that can be used to make such animals, and methods of making and using these pigs and cells. | 2014-09-11 |
20140255976 | CAPTURE, PURIFICATION, AND RELEASE OF BIOLOGICAL SUBSTANCES USING A SURFACE COATING - This invention relates to a surface coating for capture circulating rare cells, comprising a nonfouling composition to prevent the binding of non-specific cells and adsorption of serum components; a bioactive composition for binding the biological substance, such as circulating tumor cells; with or without a linker composition that binds the nonfouling and bioactive compositions. The invention also provide a surface coating for capture and purification of a biological substance, comprising a releasable composition to release the non-specific cells and other serum components; a bioactive composition for binding the biological substance, such as circulating tumor cells; with or without a linker composition that binds the releasable and bioactive compositions. The present invention also discloses a novel microfluidic chip, with specific patterned microstructures to create a flow disturbance and increase the capture rate of the biological substance. | 2014-09-11 |
20140255977 | CELL COLLECTION APPARATUS AND CELL COLLECTING METHOD - Provided is a cell collection apparatus includes: a supporter that supports a sheet to which a back surface of a substrate is pasted, the substrate being divided in to plural small pieces with a section of a tissue pasted on a front surface thereof; a needle including needle tips; and a holder that is configured to hold the needle with the needle tips facing the sheet on an opposite side to a substrate side of the sheet, and to move the needle in the forward direction of the needle tips, wherein at least two needle tips are arranged within a region narrower than the back surface of the small piece substantially on the identical plane intersecting with the longitudinal direction of the needle. | 2014-09-11 |
20140255978 | TISSUE DIVIDING APPARATUS, TISSUE DIVIDING METHOD, AND CELL COLLECTING METHOD - The present invention divides a section of a biological tissue into fragments in a size of including a sufficient amount of cells with a simple structure and a simple operation. The present invention provides a tissue dividing apparatus including: a substrate dividable into a plurality of small pieces, and having a surface to which a section of a biological tissue can be pasted; and a dividing unit that divides the substrate into a plurality of small pieces, and thereby divide the section pasted on the surface into fragments each having a substantially equivalent shape to a shape of each small piece. | 2014-09-11 |
20140255979 | METHOD OF TESTING A DISINFECTANT OR ANTIBIOTIC USING PHENANTHRIDIUM DERIVATIVES - The disclosure provides for a method of testing a disinfectant or antibiotic using phenanthridium derivatives with a 2 | 2014-09-11 |
20140255980 | MICROORGANISM DETECTING APPARATUS AND MICROORGANISM DETECTING METHOD - A microorganism detecting device includes a light source that illuminates a particle with an excitation beam, a fluorescence detector that detects fluorescence produced by the particle, an evaluating portion that evaluates that the particle is a microorganism if there is a plurality of peaks in the fluorescence spectrum, and evaluates that the particle is a non-microorganism if there is a single peak in the fluorescence spectrum. | 2014-09-11 |
20140255981 | METHOD OF CANCER DIAGNOSIS USING THE ANALYSIS OF ISOTOPES - Disclosed is a method of diagnosing cancer on the basis of the quantitative analysis of blood or tissue isotopes, for example, such as | 2014-09-11 |
20140255982 | METHOD OF CANCER DIAGNOSIS USING THE ANALYSIS OF ISOTOPES - Disclosed is a method of diagnosing cancer on the basis of the quantitative analysis of blood or tissue isotopes, for example, such as | 2014-09-11 |
20140255983 | METHOD OF CANCER DIAGNOSIS USING THE ANALYSIS OF ISOTOPES - Disclosed is a method of diagnosing cancer on the basis of the quantitative analysis of blood or tissue isotopes, for example, such as | 2014-09-11 |
20140255984 | MICRO-ORGANISM THREAT DETECTION - A method of tracking and predicting the spread of micro-organisms in an environment relies on the optical detection of the growth of micro-organisms within an analyte containing a growth medium for the micro-organism(s) to be detected. Standardisation of the containers and growth medium for each micro-organism allows rapid detection of the growth pattern of particular organisms and the implementation of a regime of remote self-reporting of results from portable incubator units ( | 2014-09-11 |
20140255985 | TWO-PHOTON ENDOSCOPIC SCANNING ASSEMBLY FOR INFLAMMATORY DISEASE DETECTION - An endscopic imaging device is described that achieves longitudinal axis (z-axis) scanning into a tissue or sample, using a piezoelectric microactuator. In some configurations, additional lateral (xy-plane) scanning is also achieved, to allow for the creation of full three-dimensional imaging, ex vivo or in vivo. The techniques may be used to image and diagnosis allergic rhinitis and eosinophilic esophagitis in tissue. | 2014-09-11 |
20140255986 | METHOD FOR AUTOMATED PROCESSING AND EMBEDDING OF TISSUE SAMPLES - An automated machine for handling and embedding tissue samples contained on microtome sectionable supports. The machine includes an input member configured to hold a plurality of the microtome sectionable supports prior to a tissue embedding operation. An output member is configured to hold a plurality of the microtome sectionable supports after the tissue embedding operation. A cooling unit is configured to hold at least one of the microtome sectionable supports during the tissue embedding operation. A motorized carrier assembly is mounted for movement and configured to hold at least one of the microtome sectionable supports. The carrier assembly moves the support from the input member to the cooling unit and, finally, to the output member. A dispensing device dispenses an embedding material onto the microtome sectionable support and at least one tissue sample carried by the microtome sectionable support during the embedding operation. | 2014-09-11 |
20140255987 | PROKARYOTE-BASED CELL-FREE SYSTEM FOR THE SYNTHESIS OF GLYCOPROTEINS - The present invention is directed to a cell-free system for producing a glycosylated protein. This system comprises an isolated oligosaccharyltransferase capable of transferring a glycan from a lipid carrier molecule to a glycoprotein target, one or more isolated glycans, where each glycan is linked to a lipid carrier molecule, and a glycoprotein target comprising one or more glycan acceptor amino acid residues or a nucleic acid molecule encoding said glycoprotein target. The present invention further relates to kits and methods for producing a glycosylated protein in this cell-free system. | 2014-09-11 |
20140255988 | MONOMERIC VARIANTS OF THE TETRAMERIC eqFP611 - DNA encoding a monomeric variant of red fluorescent protein eqFP611 comprising an amino acid sequence selected from the group consisting of SEQ ID No. 1, SEQ ID No. 3 and SEQ ID No. 5. DNA comprising a nucleotide sequence selected from the group consisting of SEQ ID No. 2, SEQ ID No. 4 and SEQ ID No. 6. | 2014-09-11 |
20140255989 | PRODUCTION OF GLYCOPROTEINS WITH LOW N-GLYCOLYLNEURAMINIC ACID (NEU5GC) CONTENT - The present invention relates to a medium for the cultivation of eukaryotic cells, the medium comprising as (an) additive(s) DMSO, N-acetylmannosamine (NAcMan), N-acetylglucosamine (NAcGlc), or any combination of two or more of these additives, including the combination of NAcMan and NAcGlc. | 2014-09-11 |
20140255990 | Genetic Element that Enhances Protein Translation - The present invention provides isolated polynucleotides that can serve as translation enhancing elements and their use in protein expression reagents and methods. | 2014-09-11 |
20140255991 | OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES - Methods for producing modified polypeptides containing amino acid analogues are disclosed. The invention further provides purified dihydrofolate reductase polypeptides, produced by the methods of the invention, in which the methionine residues have been replaced with homoallylglycine, homoproparglycine, norvaline, norleucine, cis-crotylglycine, trans-crotylglycine, 2-aminoheptanoic acid, 2-butynylglycine and allylglycine. | 2014-09-11 |
20140255992 | Process For Production Of Recombinant Human Growth Hormone - The subject invention provides an improved process for the production of human growth hormone. | 2014-09-11 |
20140255993 | MAMMALIAN CELL CULTURE - The invention provides a method for culturing mammalian cells. The method provides greater control over cell growth to achieve high product titer cell cultures by changing the temperature of the cell culture and/or by starving the cells in their asparagine supply. | 2014-09-11 |
20140255994 | Integrated Continuous Manufacturing of Therapeutic Protein Drug Substances - Provided herein are integrated continuous biomanufacturing processes for producing a therapeutic protein drug substance. Also provided are systems that are capable of continuously producing a therapeutic protein drug substance. | 2014-09-11 |
20140255995 | HIGH AFFINITY ANTIBODIES TO HUMAN IL-6 RECEPTOR - A human antibody or an antigen-binding fragment which binds human IL-6 receptor (hIL-6R) with a K | 2014-09-11 |
20140255996 | Method for Secretory Production of Protein - A method for secretory production of a heterologous protein is provided by developing a novel technique for improving ability of a coryneform bacterium to produce a heterologous protein by secretory production. By utilizing a coryneform bacterium having an ability to produce a heterologous protein by secretory production which has been modified so that the activity of a penicillin-binding protein is reduced and in which the activity of a cell surface layer protein has been reduced as an expression host, a heterologous protein is produced by secretory production. | 2014-09-11 |
20140255997 | GLUCOAMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME - The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants. | 2014-09-11 |
20140255998 | Polypeptides Having Endoglucanase Activity and Polynucleotides Encoding Same - The present invention relates to isolated polypeptides having endoglucanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 2014-09-11 |
20140255999 | SIMPLE SUGAR STARVED LIGNOCELLULOSIC BIOMASS ENZYME PRODUCTION - This specification discloses a process for producing at least one enzyme from a host cell for the hydrolysis of a first pre-treated ligno-cellulosic biomass under simple sugar starved conditions wherein the cultivation environment has very little, preferable no, simple sugars added other than those present in a ligno-cellulosic biomass used to feed and grow the host cell. The cultivation environment is substantially void of fermentation stimulators and inducers of enzyme production. Preferably, the cultivation environment has a high dry matter content of the pre-treated ligno-cellulosic biomass. | 2014-09-11 |
20140256000 | POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME - The present invention provides isolated polypeptides having cellulolytic enhancing activity and polynucleotides encoding the polypeptides, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also provides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains. | 2014-09-11 |
20140256001 | COOLING AND PROCESSING MATERIALS - Systems and methods for cooling and processing materials are disclosed. | 2014-09-11 |
20140256002 | COMPOSITION FOR BREAKING DOWN L-ASPARAGINE COMPRISING L-ASPARAGINASE, AND PRODUCTION METHOD FOR L-ASPARAGINASE - The present invention relates to a composition for breaking down L-asparagine comprising L-asparaginase, and to a production method for L-asparaginase. The L-asparaginase of the present invention differs from existing L-asparaginase in that it has improved heat stability and exhibits high activity even at high temperatures, and thus it improves upon shortcomings of existing L-asparaginase and so can be used to advantage industrially. | 2014-09-11 |
20140256003 | R-PRAZIQUANTEL PREPARATION METHOD - Provided are R-praziquantel preparation methods, which utilize the characteristics of biological enzyme of strong stereoselectivity, site-selectivity, and regioselectivity, of high resolution efficiency, of mild reaction conditions, and of simple operations to catalyze the hydrolysis of a certain enantiomer in a chemically synthesized racemate or a derivative, thus acquiring a mixture of reacted and unreacted optical isomers. R-praziquantel prepared by the method can have a purity of 98% or more. | 2014-09-11 |
20140256004 | Process for the Preparation of an Endothelin Receptor Antagonist - The present invention relates to a novel process for the preparation of a compound of formula (I) wherein R is a methyl or methoxy group; to certain novel intermediates prepared in such a process and their use. | 2014-09-11 |
20140256005 | PROCESS FOR THE PRODUCTION OF GAMMA-AMINOBUTYRIC ACID - The present invention relates to a novel method for the fermentative production of gamma-aminobutyric acid (GABA) by cultivating a recombinant microorganism expressing an enzyme having a glutamate decarboxylase activity. The present invention also relates to corresponding recombinant hosts, recombinant vectors, expression cassettes and nucleic acids suitable for preparing such hosts as well as to a method for preparing polyamides making use of GABA as obtained fermentative production. | 2014-09-11 |
20140256006 | PROCESSES FOR PRODUCING HYDROCARBON PRODUCTS - The present invention relates to processes for producing industrial products such as hydrocarbon products from non-polar lipids in a vegetative plant part. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels. | 2014-09-11 |
20140256007 | MEMBRANES FOR WASTEWATER-GENERATED ENERGY AND GAS - An example includes an apparatus, method, and system for producing and extracting a gas from a wastewater fluid. The apparatus can include a membrane including at least one hollow fiber, the at least one hollow fiber configured to convey a gas extracted from a wastewater fluid. Bacteria can be immobilized within the membrane, and the bacteria configured to produce the gas during treatment of the wastewater fluid. | 2014-09-11 |
20140256008 | NEW BIOSYNTHESIS PATHWAY FOR PRENOL IN A RECOMBINANT MICROORGANISM - The present invention concerns a method for the biological preparation of prenol comprising culturing a microorganism genetically modified for the bioproduction of prenol, wherein the microorganism comprises a metabolic pathway for conversion of 3-methylcrotonyl-CoA into prenol by the action of an alcool dehydrogenase enzyme and of an aldehyde dehydrogenase enzyme. | 2014-09-11 |
20140256009 | METHOD FOR THE ENZYMATIC PRODUCTION OF BUTADIENE - Described is a method for the enzymatic production of butadiene which allows to produce butadiene from crotyl alcohol. Also described are enzyme combinations and compositions containing such enzyme combinations which allow the enzymatic conversion of crotyl alcohol into butadiene. Furthermore, the invention relates to microorganisms which have been genetically modified so as to be able to produce butadiene from crotyl alcohol. | 2014-09-11 |
20140256010 | CATALYTIC CONVERSION OF ALCOHOLS TO HYDROCARBONS WITH LOW BENZENE CONTENT - A method for converting an alcohol to a hydrocarbon fraction having a lowered benzene content, the method comprising: converting said alcohol to a hydrocarbon fraction by contacting said alcohol, under conditions suitable for converting said alcohol to said hydrocarbon fraction, with a metal-loaded zeolite catalyst catalytically active for converting said alcohol to said hydrocarbon fraction, and contacting said hydrocarbon fraction with a benzene alkylation catalyst, under conditions suitable for alkylating benzene, to form alkylated benzene product in said hydrocarbon fraction. Also described is a catalyst composition useful in the method, comprising a mixture of (i) a metal-loaded zeolite catalyst catalytically active for converting said alcohol to said hydrocarbon, and (ii) a benzene alkylation catalyst, in which (i) and (ii) may be in a mixed or separated state. A reactor for housing the catalyst and conducting the reaction is also described. | 2014-09-11 |
20140256011 | Method for Acetate Consumption During Ethanolic Fermentaion of Cellulosic Feedstocks - The present invention provides for novel metabolic pathways to detoxify biomass-derived acetate via metabolic conversion to ethanol, acetone, or isopropanol. More specifically, the invention provides for a recombinant microorganism comprising one or more native and/or heterologous enzymes that function in one or more first engineered metabolic pathways to achieve: (1) conversion of acetate to ethanol; (2) conversion of acetate to acetone; or (3) conversion of acetate to isopropanol; and one or more native and/or heterologous enzymes that function in one or more second engineered metabolic pathways to produce an electron donor used in the conversion of acetate to less inhibitory compounds; wherein the one or more native and/or heterologous enzymes is activated, upregulated, or downregulated. | 2014-09-11 |
20140256012 | PROCESS FOR THE PRODUCTION OF ALCOHOLS AND/OR SOLVENTS FROM LIGNOCELLULOSIC BIOMASS WITH WASHING OF THE SOLID RESIDUE OBTAINED AFTER HYDROLYSIS - The process for the production of alcohol and/or solvent from a biomass feedstock comprises the stages for pretreatment (P) of the biomass feedstock, for enzymatic hydrolysis (H) of the pretreated substrate, and for fermenting the hydrolyzate (F). | 2014-09-11 |
20140256013 | PRODUCTION, STORAGE AND USE OF CELL WALL-DEGRADING ENZYMES - A process of producing a preparation of cell wall-degrading enzymes, comprising: expressing in plants or plant parts one or more than one heterologous cell wall-degrading enzyme; harvesting said plants or plant part containing said one or more than one cell wall-degrading enzyme; and storing the harvest as a silage. The silage may be used for degrading cell wall components of plant material or for producing a bioalcohol. | 2014-09-11 |
20140256014 | METHODS AND SYSTEMS FOR ABSORBING CO2 AND CONVERTING SAME INTO GASEOUS OXYGEN BY MEANS OF MICROORGANISMS - Methods and systems are described for the purification of contaminated air containing CO | 2014-09-11 |
20140256015 | CAGED COMPOUND WHICH CAN BE PHOTOACTIVATED SELECTIVELY FOR CELL TYPES - An objective of the present invention is to provide a caged compound that can be photoactivated selectively for specific target cell types and can be used in an individual organism. The objective can be achieved by a compound represented by general formula K-Q-X, which is prepared by binding bioactive substance X, photocleavable protecting group Q, and compound K, which can be an enzyme substrate and is dissociated from Q-X by an enzyme reaction, wherein: Q is a protecting group that is photocleaved by light with a specific wavelength and then dissociated from X, when K is not bound thereto; X is a substance that does not express bioactivity when Q is bound thereto, but expresses bioactivity when Q is dissociated therefrom; and K is dissociated from Q by the above enzyme, so as to form a compound represented by Q-X. Specifically, the objective can be achieved with the use of such a compound, which is characterized in that Q is dissociated from X when the compound represented by Q-X is photoirradiated, and thus K expresses bioactivity. | 2014-09-11 |
20140256016 | 2-Aminopyridine-based Selective Neuronal Nitric Oxide Synthase Inhibitors - Aminopyridine compounds, as can be used in conjunction with methods for modulation of nitric oxide synthase activity. | 2014-09-11 |
20140256017 | SACCHARIDE-CONTAINING PROTEIN CONJUGATES AND USES THEREOF - Conjugates of a saccharide and a biomolecule, covalently linked therebetween via a non-hydrophobic linker and methods of preparing same are disclosed. Also disclosed are medical uses utilizing such conjugates. Glycosylation reagents for use in preparing these conjugates are also disclosed. Glycosylated proteins, characterized by improved performance, are also disclosed. | 2014-09-11 |
20140256018 | BETA-GLUCOSIDASE VARIANTS - The invention relates to recombinantly produced β-glucosidase variants with enhanced thermoactivity compared to naturally occurring proteins. The invention also provides methods for producing a variant β-glucosidase polypeptide with improved thermoactivity by identifying performance sensitive positions in a target β-glucosidase polypeptide and substituting the residue at that position with a thermoactivity enhancing residue. | 2014-09-11 |
20140256019 | Compositions and Methods for Inhibiting Viral Adhesion - The present invention provides compositions and methods for treating or preventing viral infections. | 2014-09-11 |
20140256020 | IN SITU EXPRESSION OF LIPASE FOR ENZYMATIC PRODUCTION OF ALCOHOL ESTERS DURING FERMENTATION - Disclosed herein are methods of producing alcohol esters during a fermentation by providing alcohol-producing microorganisms which further comprise an engineered polynucleotide encoding a polypeptide having lipase activity. | 2014-09-11 |
20140256021 | BIOFILTER MEDIA TO REMOVE ODOUR CAUSING COMPOUNDS FROM WASTE GAS STREAMS - A biofilter media has one or more of a set of desired physical characteristics. The set of physical characteristics includes a sphericity of 0.75 to 1, a particle size of 1 to 16 or 4 to 8 mm, a uniformity coefficient of 2 or less and a surface area of 800 to 2000 m | 2014-09-11 |
20140256022 | PHOTOBIOREACTOR - A photobioreactor having an optical waveguide formed at least in part from highly scattering optically transmitting polymer. The optical waveguide has a light distributing part immersed in a container holding photoactive biological material and a light collecting part outside the container. | 2014-09-11 |
20140256023 | BIOMASS-PRODUCTION METHOD AND APPARATUS USED IN SAID METHOD - The invention relates to a method for accelerating biomass production, based on the culture of microalgae, using, for implementing said method, a reactor specifically designed therefor, in which a culture of water with microalgae, with nutrients and CO2 is placed in said reactor, a direct current being passed through the interior thereof. | 2014-09-11 |
20140256024 | Nucleic Acids Useful in the Manufacture of Oil - Novel gene sequences from microalgae are disclosed, as well as novel gene sequences useful in the manufacture of triglyceride oils. Also disclosed are sequences and vectors that allow microalgae to be cultivated on sugar cane and sugar beets as a feedstock. In some embodiments, the vectors are useful for the purpose of performing targeted modifications to the nuclear genome of heterotrophic microalgae. | 2014-09-11 |
20140256025 | METHODS AND ENZYMATIC DETERGENTS FOR REMOVING BIOFILM - A composition for cleaning a medical instrument having a surface at least partially covered by a biofilm. The composition may include a first enzyme having a weight of less than about 10% of the total weight of the composition, a second enzyme having a weight of less than about 10% of the total weight of the composition, and a surfactant having a weight less than about 10% of the total weight of the composition. The second enzyme may be different from the first enzyme. Additionally, the composition may have a pH ranging from about 4 to about 12, and the composition may be configured to remove greater than about 90% of the biofilm from the medical instrument in less than about 10 minutes. | 2014-09-11 |
20140256026 | BIOLOGICAL COMPOSITIONS FOR THE PRODUCTION OF FUNCTIONALLY CONSISTENT PRODUCTS - Several embodiments of the invention relate generally to a system and methods for the treatment of gaseous emissions comprising methane and one or more non-methane compounds that can influence the metabolism of methane-oxidizing microorganisms. In several embodiments, there is provided a system and methods for the treatment of methane emissions through the use of methanotrophic microorganisms to generate functionally consistent and harvestable products. Certain embodiments of the invention are particularly advantageous because they reduce environmentally-destructive methane emissions and produce harvestable end-products. | 2014-09-11 |
20140256027 | Perfusion Culture Method and Perfusion Culture Device for Organ or Tissue - Disclosed are a perfusion culture method and a perfusion culture device whereby a perfusate can be delivered to all parts of an organ or tissue so that the organ or tissue can be preserved while sufficiently maintaining the function thereof. Specifically disclosed is a method for perfusion culture of an organ or tissue removed from a mammal, said organ or tissue having been removed together with a second organ or tissue connected to the aforesaid organ or tissue in vivo, which comprises a step for fixing said second organ or tissue so as to hang the aforesaid organ or tissue and a step for perfusing blood vessels in the aforesaid organ or tissue with a perfusate. | 2014-09-11 |
20140256028 | SEMICONDUCTOR MICRO-ANALYSIS CHIP AND MANUFACTURING METHOD THEREOF - According to one embodiment, a semiconductor micro-analysis chip for detecting fine particles in sample liquid includes a semiconductor substrate, a first flow channel that is formed in the semiconductor substrate and into which the sample liquid is introduced, and a plurality of columnar structures fully arranged in the first flow channel at regulation distance. | 2014-09-11 |
20140256029 | APPARATUS FOR POLYNUCLEOTIDE DETECTION AND QUANTITATION - An apparatus for expression profiling analysis, subjecting biological materials to polynucleotide extraction, amplification and analysis. The apparatus include an amplification device which permits the amplification of polynucleotides and an analysis device which quantifies the amount of the amplified polynucleotide products. The amplification device of the apparatus may further permit polynucleotide extraction to prepare the template for amplification, or sequence identification of a quantified polynucleotide product. A fraction collector may be included in the apparatus to collect a qualified polynucleotide product before its sequence is identified. The analysis device may further permit data generation, or alternatively, data can be generated by a separate data generation device provided with the apparatus. The devices within the apparatus are connected by connecting means which permit the transfer of a fluid or a signal for amplification and analysis. | 2014-09-11 |
20140256030 | Scalable Biochip and Method for Making - The present disclosure provides a biochip and methods of fabricating. The biochip includes a fluidic part and a sensing part bonded together using a polymer. The fluidic part has microfluidic channel pattern on one side and fluidic inlet and fluidic outlet on the other side that are fluidly connected to the microfluidic channel pattern. The fluidic inlet and fluidic outlet are formed by laser drilling after protecting the microfluidic channel pattern with a sacrificial protective layer. The polymer bonding is performed at low temperature without damaging patterned surface chemistry on a sensing surface of the sensing part. | 2014-09-11 |
20140256031 | SEMICONDUCTOR MICRO-ANALYSIS CHIP AND SAMPLE LIQUID FLOWING METHOD - According to one embodiment, a semiconductor micro-analysis chip for detecting fine particles in sample liquid includes a semiconductor substrate, a flow channel formed in the semiconductor substrate and having a sample liquid inlet and sample liquid outlet at end portions thereof, and an absorber provided on at least part of the sample outlet of the flow channel to absorb the sample liquid. | 2014-09-11 |
20140256033 | DEVICES FOR DETERMINING CELL FORCE PROPERTIES AND METHODS OF MANUFACTURING THE DEVICES - A device may be configured to allow individual measuring of at least one property of at least one cell, such as measuring a contraction force of a platelet. The device may include a plurality of wells. Each well may include a hydrogel layer, the hydrogel layer including a hydrogel having a top surface that includes a pattern of cell interaction regions. The wells may differ in stiffness properties of the hydrogel and/or biochemical conditions. Each cell interaction region may include a group of at least two cell interaction sites. The spacing between each cell interaction region may be greater than a spacing between the at least two cell interaction sites of each cell interaction region. In this way, cell-cell interactions may be reduced and thereby increasing number of individual cells capable of being measured. | 2014-09-11 |
20140256034 | BIO-PIN - A bio-pin is provided. The bio-pin can be used for cell transfer and treatment, cell tracing, and targeting of specific tissues and cells using a peptide-based complex in which a cell-penetrating peptide or a cell-adhesive peptide is bound to one or both ends of a cell membrane protein, and used in a molecular imaging system, a medical appliance, and the like. | 2014-09-11 |
20140256035 | METHOD FOR DETOXIFYING A BIOLOGICAL TISSUE - Biological tissues may be prepared for use in biological prostheses. The biological tissue may be fixated with glutaraldehyde and may be subjected to successive treatment of the tissue with a solution containing taurine to neutralize excess aldehyde groups that remain free after fixation. | 2014-09-11 |
20140256036 | HIGH-DENSITY SPOT SEEDING FOR TISSUE MODEL FORMATION - A model of tissue is produced by steps comprising seeding cells at a selected concentration on a support to form a cell spot, incubating the cells to allow the cells to partially attach, rinsing the cells to remove any cells that have not partially attached, adding culture medium to enable the cells to proliferate at a periphery of the cell spot and to differentiate toward a center of the cell spot, and further incubating the cells to form the tissue. The cells may be C2C12 cells or other subclones of the C2 cell line, H9c2(2-1) cells, L6 cells, L8 cells, QM7 cells, Sol8 cells, G-7 cells, G-8 cells, other myoblast cells, cells from other tissues, or stem cells. The selected concentration is in a range from about 1×10 | 2014-09-11 |
20140256037 | CULTURE MEDIUM FOR EPITHELIAL STEM CELLS AND ORGANOIDS COMPRISING THE STEM CELLS - The invention relates to a method for culturing epithelial stem cells, isolated tissue fragments comprising said epithelial stem cells, or adenoma cells, and culturing the cells or fragments in the presence of a Bone Morphogenetic Protein (BMP) inhibitor, a mitogenic growth factor, and a Wnt agonist when culturing epithelial stem cells and isolated tissue fragments. The invention further relates to a cell culture medium comprising a BMP inhibitor, a mitogenic growth factor, and a Wnt agonist, to the use of said culture medium, and to crypt-villus organoids, gastric organoids and pancreatic organoids that are formed in said culture medium. | 2014-09-11 |
20140256038 | Peptide-Bound Gold Metal Nano-clusters as Cancer Cell Killing Agents - Peptide-bound gold metal nanocluser complexes are produced to induce cancer cell death by dramatically inhibiting TrxR activities of the cancer cells. Specificity is shown by selectively designing peptide sequences. | 2014-09-11 |
20140256039 | COMPOSITIONS AND METHODS OF INHIBITING NEURONAL CELL DEATH - A method of inhibiting β-amyloid (Aβ) induced neuronal cell death includes administering to a neuronal cell exposed to a neurotoxic amount of Aβ a therapeutically effective amount of cell penetrating peptide (CPP). The CPP has an amino acid sequence that has at least 80% sequence identity to about 5 to about 41 consecutive amino acids of SEQ ID NO: 1. | 2014-09-11 |
20140256040 | DIAGNOSIS AND TREATMENT OF CANCERS WITH MICRORNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES - MicroRNA genes are highly associated with chromosomal features involved in the etiology of different cancers. The perturbations in the genomic structure or chromosomal architecture of a cell caused by these cancer-associated chromosomal features can affect the expression of the miR gene(s) located in close proximity to that chromosomal feature. Evaluation of miR gene expression can therefore be used to indicate the presence of a cancer-causing chromosomal lesion in a subject. As the change in miR gene expression level caused by a cancer-associated chromosomal feature may also contribute to cancerigenesis, a given cancer can be treated by restoring the level of miR gene expression to normal. microRNA expression profiling can be used to diagnose cancer and predict whether a particular cancer is associated with an adverse prognosis. The identification of specific mutations associated with genomic regions that harbor miR genes in CLL patients provides a means for diagnosing CLL and possibly other cancers. | 2014-09-11 |
20140256041 | METHODS OF BLOCKING CANCER STEM CELL GROWTH - Disclosed herein are antibodies against GPR49 and uses of such antibodies. The antibodies can be monoclonal, humanized, or fully human antibodies against GPR49, hybridomas or other cell lines expressing such antibodies, nucleic acids and vectors comprising nucleic acids encoding for such antibodies, and methods of blocking cancer stem cell growth with such antibodies. | 2014-09-11 |
20140256042 | METHOD OF PRODUCING ERYTHROCYTES WITHOUT FEEDER CELLS - Provided herein are methods of producing erythrocytes from hematopoietic cells, particularly hematopoietic cells from placental perfusate in combination with hematopoietic cells from umbilical cord blood, wherein the method results in accelerated expansion and differentiation of the hematopoietic cells to more efficiently produce administrable erythrocytes. Further provided herein is a bioreactor in which hematopoietic cell expansion and differentiation takes place. | 2014-09-11 |
20140256043 | SMALL CHEMICAL COMPOUND WHICH PROMOTES INDUCTION OF DIFFERENTIATION OF STEM CELLS INTO INSULIN-PRODUCING CELLS AND METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO INSULIN-PRODUCING CELLS USING SAID SMALL CHEMICAL COMPOUND - A purpose of the present invention is to provide a small chemical compound which especially promotes induction of the differentiation of ES cells into insulin-producing cells. Another purpose of the present invention is to provide: a method for inducing the differentiation of ES cells into insulin-producing cells using the compound; and an agent for promoting induction of the differentiation into insulin-producing cells. Another purpose of the present invention is to provide the thus-induced insulin-producing cells. Provided are: an agent for promoting induction of the differentiation of stem cells derived from a mammal into insulin-producing cells, which contains a compound that is selected from the group consisting of dopamine metabolism inhibitors, serotonin metabolism inhibitors, acetylchotine, acetylcholine degrading enzyme inhibitors and acetylcholine receptor activators; and a method for inducing differentiation using the agent for promoting induction of differentiation. | 2014-09-11 |
20140256044 | CULTURE MEDIA - This document provides methods and materials involved in creating immortalized cell lines (e.g., immortalized breast, ovarian, or prostate cancer cell lines) and culturing immortalized cell lines. For example, culture media that can be used to create immortalized breast, ovarian, or prostate cancer cell lines are provided. | 2014-09-11 |
20140256045 | METHOD OF CONSTRUCTION OF RECOMBINANT ORGANISMS USING MULTIPLE GENES CO-INTEGRATION - Provided is a method of simultaneous co-integration of multiple nucleic acid sequences into a microbial organism comprising culturing a microbial organism to be transformed until a growth phase is reached in which a random integration is facilitated; and transforming the microbial organism by mixing the cultured microbial organism with a sample to be co-integrated into the microbial organism with, wherein the sample comprises more than one nucleic acid sequence, and the products generated from the method. | 2014-09-11 |
20140256046 | ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION WITH FUNCTIONAL DOMAINS - The invention provides for engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors with additional functional domains. Also provided are methods of directing CRISPR complex formation in prokaryotic and eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity. | 2014-09-11 |
20140256047 | DOSE AND LOCATION CONTROLLED DRUG/GENE/PARTICLE DELIVERY TO INDIVIDUAL CELLS BY NANOELECTROPORATION - A simple and low cost method of producing sealed arrays of laterally ordered nanochannels interconnected to microchannels of tunable size, over large surface areas, is disclosed. The method incorporates DNA combing and subsequent imprinting. Associated micro and macroscale inlets and outlets can be formed in the same process or manufactured later in low cost, non-cleanroom techniques. The techniques embrace two procedures, generating DNA nanostrands and translating these strands into nanoscale constructs via imprinting. Devices incorporating the novel arrays have a first microchannel, a second microchannel and a nanochannel that is substantially linear and which defines an axis. The nanochannel is connected at its open ends to the microchannels, which are aligned along the axis. Methods for precise dose delivery of agents into cells employing the devices in nanoelectroporation methods are also disclosed. | 2014-09-11 |
20140256048 | BACTERIAL XYLOSE ISOMERASES ACTIVE IN YEAST CELLS - Specific polypeptides were identified as bacterial xylose isomerases that are able to provide xylose isomerase activity in yeast cells. The xylose isomerase activity can complete a xylose utilization pathway so that yeast can use xylose in fermentation, such as xylose in biomass hydrolysate. | 2014-09-11 |
20140256049 | COW RUMEN XYLOSE ISOMERASES ACTIVE IN YEAST CELLS - Polypeptides were identified among translated coding sequences from a metagenomic cow rumen database, that were shown to provide xylose isomerase activity in yeast cells. The xylose isomerase activity can complete a xylose utilization pathway so that yeast can use xylose in fermentation, such as xylose in biomass hydrolysate. | 2014-09-11 |
20140256050 | SAMPLE PROCESSING APPARATUS, SAMPLE RACK SET, AND SAMPLE PROCESSING METHOD - A sample processing apparatus comprises a transporting section configured to transport a sample rack that is capable of holding a sample container at a plurality of holding positions, a detecting section that is configured to detect presence or absence of a rack distinction member at a holding position of the sample rack, an aspirating section that is configured to aspirate a sample in the sample container, and a control section that is configured to control an aspirating operation of the aspirating section. The control section changes an aspirating operation with respect to the sample container held in the sample rack based on the presence/absence of the rack distinction member at the holding position of the sample rack. | 2014-09-11 |
20140256051 | DECARBOXYLATION DOSIMETRY - Methods and apparatuses of the present disclosure provide accurate and precise radiation dosimetry based on decarboxylation of a reactant upon exposure to ionizing radiation. The decarboxylation reaction yields carbon dioxide and stable end products, which can be detected and measured, and correlated to determine an amount of radiation exposure. The reactants include carboxyl acids, such as amino acids and others occurring naturally in mammals. The dosimetry may be performed in real-time or retrospectively by assaying a sample of tissue from a patient. Also disclosed is a device which detects and measures radiation dosages based on decarboxylation of a reactant contained therein. | 2014-09-11 |
20140256052 | APPARATUS AND METHOD FOR ANALYZING BLOOD CLOTTING - The invention includes systems, apparatuses and methods to evaluate the strength of clotting in addition to or separate from activated clotting time. The strength of clotting may be correlated with the amount of energy employed to move an object within blood. The strength of clotting may be correlated with the amount of time for fibrinolysis to occur. The strength of clotting may be determined by a system in which a ferromagnetic material is moved within blood. | 2014-09-11 |
20140256053 | REVERSIBLE COLOR-CHANGING INK FORMULATIONS AND NONWOVEN WIPES - A reversible color-changing ink formulation, and a nonwoven wipe to which the ink formulation is securely bound, are provided. The reversible color-changing ink formulation includes about 55-98% by weight of a polymer binder, about 0.1-20% by weight of a reversible color-changing dye that reversibly changes between a first color and a second color at a pH of about 5.5 to about 8.0, and optional amounts of plasticizer, inorganic particulate filler, and color brightener. During use, the nonwoven wipe is impregnated with a sanitizer solution that contains a quaternary ammonium compound. The nonwoven wipe reversibly changes between a first color when impregnated with the sanitizer solution and a second color when the sanitizer solution is depleted during use. The change to the second color indicates the need to recharge the nonwoven wipe with the sanitizer solution, whereupon the first color returns. | 2014-09-11 |
20140256054 | METHODS FOR ELEMENTAL ANALYSIS BY COMBUSTING A SAMPLE IN A COMBUSTION TUBE - Methods are provided for conducting chemical analyses by combusting a sample in a combustion tube. A primary combustion chamber receives and combusts a sample to form first combustion products. A secondary combustion chamber receives and combusts the first combustion products to form second combustion products. The secondary chamber is disposed around the primary chamber and comprises a plurality of—preferably, three—combustion compartments. Each successive compartment is disposed around the preceding compartment and defines a respective gas flow channel having an inlet opening and an outlet opening at opposite ends. Each successive gas flow channel shares its inlet opening with the outlet opening of the preceding channel. The plurality of combustion compartments define a substantially continuous gas flow conduit from the inlet opening of the innermost compartment to the outlet opening of the outermost compartment. Static gas mixers may be employed to enhance mixing of the combustion products. | 2014-09-11 |
20140256055 | EXPLORATION METHOD AND SYSTEM FOR DETECTION OF HYDROCARBONS - A method for detecting hydrocarbons is described. The method includes performing a remote sensing survey of a survey location to identify a target location. Then, an underwater vehicle (UV) is deployed into a body of water and directed to the target location. The UV collects measurement data within the body of water at the target location, which is then analyzed to determine whether hydrocarbons are present at the target location. | 2014-09-11 |
20140256056 | METHOD TO CALIBRATE DISPOSABLE CARTRIDGE CUVETTE THICKNESS IN-SITU - An analytical system includes a laser disposed to direct light toward a microfluidic feature disposed in a feature layer of a multiple layer test cartridge, a sensor to receive reflections from capping layers disposed about the microfluidic feature in the feature layer, and a controller to determine a depth of the microfluidic feature as a function of the received reflections. | 2014-09-11 |
20140256057 | CHEMICAL SENSOR, BIOMOLECULE DETECTION APPARATUS, AND BIOMOLECULE DETECTION METHOD - [Object] To provide a chemical sensor, a biomolecule detection apparatus, and a biomolecule detection method capable of detecting a biomolecule with high accuracy. | 2014-09-11 |
20140256058 | SAMPLE TUBE WITH IMPROVED LID - The present invention discloses a lid for a sample tube and a sample tube enabling ventilation or sealing depending on the closing position of the lid. Furthermore, a method for drying a sample and a use of the above lid or of the above sample tube for storing or drying a sample are subjects of the present invention. | 2014-09-11 |
20140256059 | MULTICOLOR MICROWAVE-ACCELERATED METAL-ENHANCED FLUORESCENCE (M-MAMEF) - The present invention relates to the use of multiple different light emitting molecules that emit different and detectable emission signals to provide systems and methods to detect different target products in a single assay sample, wherein the different light emitting molecules are positioned an optimal distance from metallic particles thereby enhancing emissions. Preferably, the systems and methods further comprise use of either microwave or sonic energy to increase binding reactions, timing of such reactions within the assay sample and reduce background non-specific biological absorption. | 2014-09-11 |
20140256060 | pH-INSENSITIVE GLUCOSE INDICATOR PROTEIN - The present invention encompasses a glucose indicator protein, a biosensor comprising one or more glucose indicator proteins, and methods of use thereof. | 2014-09-11 |
20140256061 | Method of Etching MTJ Using CO Process Chemistries - A method for fabricating a magnetic film structure is provided. The method comprises forming a magnetic structure on a bottom electrode layer, the magnetic structure comprising at least one pinned bottom magnetic film layer having a fixed magnetic orientation; at least one top magnetic film layer whose magnetic orientation can be manipulated by a current; and a tunneling layer between the bottom magnetic film layer and the top magnetic film layer; forming a metallic hard mask atop the magnetic structure; patterning and etching the metallic hard mask to define exposed areas of the magnetic structure; selectively etching the exposed areas of the magnetic structure by a chemical etch process based on a CO etch chemistry to form discrete magnetic bits. | 2014-09-11 |
20140256062 | METHOD FOR FABRICATING NONVOLATILE MEMORY DEVICE - A method for fabricating a nonvolatile memory device is provided. The method includes forming a transistor including an impurity region formed in a substrate, forming a first interlayer insulation layer covering the transistor, the first interlayer insulation layer including a protrusion overlapping the impurity region, and forming an information storage unit on the protrusion, the information storage unit exposing side surfaces of the protrusion using point cusp magnetron-physical vapor deposition (PCM-PVD) and electrically connected to the impurity region. | 2014-09-11 |
20140256063 | CONTACTLESS COMMUNICATIONS USING FERROMAGNETIC MATERIAL - A communications structure comprises a first semiconductor substrate having a first coil, and a second semiconductor substrate having a second coil above the first semiconductor substrate. Inner edges of the first and second coils define a boundary of a volume that extends below the first coil and above the second coil. A ferromagnetic core is positioned at least partially within the boundary, such that a mutual inductance is provided between the first and second coils for wireless transmission of signals or power between the first and second coils. | 2014-09-11 |
20140256064 | METHODS OF REPAIRING DAMAGED INSULATING MATERIALS BY INTRODUCING CARBON INTO THE LAYER OF INSULATING MATERIAL - One illustrative method disclosed herein includes providing a layer of a carbon-containing insulating material having a nominal carbon concentration, performing at least one process operation on the carbon-containing insulating material that results in the formation of a reduced-carbon-concentration region in the layer of carbon-containing insulating material, wherein the reduced-carbon-concentration region has a carbon concentration that is less than the nominal carbon concentration, performing a carbon-introduction process operation to introduce carbon atoms into at least the reduced-carbon-concentration region and thereby define a carbon-enhanced region having a carbon concentration that is greater than the carbon concentration of the reduced-carbon-concentration region and, after introducing the carbon atoms, performing a heating process on at least the carbon-enhanced region. | 2014-09-11 |
20140256065 | ETCHING METHOD - There is provided an etching method. A temperature at a plurality of predetermined positions on an upper surface of an Si substrate is measured during the etching processing. The etching processing includes supplying an etching solution to the upper surface of the Si substrate. An exothermic reaction occurs in the etching processing. The upper surface is heated or cooled depending on the measured value. | 2014-09-11 |