37th week of 2022 patent applcation highlights part 40 |
Patent application number | Title | Published |
20220291122 | A METHOD OF DETERMINING PETROLEUM HYDROCARBON FRACTIONS IN A SAMPLE - The present invention relates to a method of determining petroleum hydrocarbon fractions (Cn) in a sample, the method including: inputting the sample into a chamber; emitting infrared light from an optical light source into the chamber with the sample; detecting at a detector a detected infrared light from the chamber; transforming the detected infrared light to a Fourier Transform Infrared (FTIR) spectrum of the sample at a processor, wherein the FTIR spectrum has wavenumbers between 4000 and 400 cm−1; processing the FTIR spectrum to identify sub-bands each having at least one doublet of sub-band peaks at respective wavenumbers in a second derivative curve of the FTIR spectrum using a second derivation algorithm implemented by the processor; comparing the at least one doublet of sub-band peaks to data indicative of known doublets of sub-band peaks at known wavenumbers for petroleum hydrocarbon fractions in the FTIR spectrum to classify the petroleum hydrocarbon fractions in the sample; and determining a dominant petroleum hydrocarbon fraction of the petroleum hydrocarbon fractions in the sample based on a ratio of intensities of the sub-band peaks of the at least one doublet for each of the petroleum hydrocarbon fractions in the sample. | 2022-09-15 |
20220291123 | GAS DETECTION DEVICE, GAS DETECTION SYSTEM, AND GAS DETECTION METHOD - A gas detection that includes a projector including a light source that emits laser light having a wavelength at which an absorption rate by a detection target gas is high and a spatial light modulator that modulates the laser light emitted from the light source, a projection control unit that controls projection light to be projected toward a retroreflector by causing the light source to emit the laser light and setting a pattern of a modulation part of the spatial light modulator, a light receiver that receives reflected light of the projection light reflected by the retroreflector and measures an intensity of the received reflected light; and a leakage determination unit that acquires the intensity of the reflected light from the light receiver and determines leakage of the detection target gas in a detection space with the retroreflector based on the intensity of the reflected light. | 2022-09-15 |
20220291124 | NONINVASIVE VACCINE TESTER - This invention this invention is a device and method for validating the identity of a liquid in a container that is transparent to light, while the liquid is in the container, without physically invading container. The liquid is particularly suited for validating vaccines such as the vaccine for COVID-19. The invention uses light from a refractometer and/or nephelometer, passing into and reflected out of the transparent wall of the container, to characterize the liquid. | 2022-09-15 |
20220291125 | ABLATION SENSOR WITH OPTICAL MEASUREMENT - A real-time ablation sensor uses an optical detector, such as a spectrometer or radiometer, to detect ablation of a material, for example by detecting a signal indicative of ablation of the material, which may be an engineered material. The optical detector may detect reflected light, either from the material being ablated, or from products of the ablation, such as in the vicinity of the material being ablated. A light source may be used to provide light that is reflected by the material and/or the ablation products, with the reflected light received by the detector. The light may be of a selected wavelength or wavelengths, with the selection made in combination with the selection/configuration of the material to be ablated, and/or the selection/configuration of the optical detector. | 2022-09-15 |
20220291126 | DEVICE INCLUDING OPTOFLUIDIC SENSOR WITH INTEGRATED PHOTODIODE - A “lab on a chip” includes an optofluidic sensor and components to analyze signals from the optofluidic sensor. The optofluidic sensor includes a substrate, a channel at least partially defined by a portion of a layer of first material on the substrate, input and output fluid reservoirs in fluid communication with the channel, at least a first radiation source coupled to the substrate adapted to generate radiation in a direction toward the channel, and at least one photodiode positioned adjacent and below the channel. | 2022-09-15 |
20220291127 | AN ARTICLE COMPRISING FLUORESCENCE MARKER PARTICLES AND A METHOD OF IDENTIFYING THE SAME - The present invention relates to an article comprising fluorescence marker particles, wherein the fluorescence marker particles are distributed throughout the volume of the article or in a portion of the volume of the article and the fluorescence marker particles are present in a random distribution; the volume in which the fluorescence marker particles are distributed comprises a sub-volume; the sub-volume contains at least a portion of the fluorescence marker particles; the sub-volume is at least partially permeable to electromagnetic radiation having a wavelength in the visible range and/or in the near infrared range and/or in the UVA range; and/or a portion of the surface of the sub-volume is identical to a portion of the surface of the article; and a method of identifying it. | 2022-09-15 |
20220291128 | Continuous Flow Air Sampling and Rapid Pathogen Detection System - Methods and devices for continuous flow monitoring of a liquid sample for presence of an airborne microbial pathogen are provided. The liquid sample can be derived from environmental air. The methods and devices provide for continuous labeling of a targeted pathogen in the liquid sample with a fluorescent probe. A customized fluorescence detector is provided that can detect labeled pathogens during continuous flow. | 2022-09-15 |
20220291129 | INTEGRATED FLUORESCENCE SCANNING SYSTEM - An integrated fluorescence scanning system is provided. The integrated fluorescence scanner combines an embedded computer, light engine, microscope, and motion stage into a compact rack-mountable network appliance that allows for automation of fluorescence microscopy. In an embodiment, the integrated fluorescence scanner includes a solid-state light engine which can provide intense, pure, and stable light across the spectrum required for imaging of all fluorophores of interest. The embedded computer allows for autonomous operation, and network appliance features including synchronous multi-scanner operation and monitoring, multisite operation via a single control terminal, and calibration for inter and intra instrument consistency. | 2022-09-15 |
20220291130 | Diagnostic Device Based On Surface-Enhanced Raman Scattering - Embodiments are directed to diagnostic devices based on surface-enhanced Raman scattering comprising: an inlet module receiving liquid to be analyzed; a reaction module having a first region arranged with a receiving hole and a second region arranged with an output hole, wherein the receiving hole is communicated with the output hole through a flow channel configured with at least one chemical set, the reaction module receives the liquid delivered by the inlet module via the receiving hole, and the liquid to be analyzed flows through the chemical sets placed in the flow channel to obtain nanoparticles-carrying liquid, and the nanoparticles-carrying liquid configured to flow into the second region of the reaction module; and a detection module receiving the nanoparticle-carrying liquid from the output hole of the reaction module. | 2022-09-15 |
20220291131 | BODILY FLUID TESTING EQUIPMENT - An application-analysable bodily fluid testing equipment ( | 2022-09-15 |
20220291132 | BODILY FLUID TESTING METHOD - A method for determining an indicator of a bodily condition in an image of a bodily fluid testing equipment captured by an electronic device is provided. The method comprises determining colour data of a first bodily fluid testing region ( | 2022-09-15 |
20220291133 | TEST DEVICE, ASSEMBLY, AND METHOD - Analyte testing devices, assemblies, methods, operations, and systems are shown and described. In one embodiment, an apparatus to generate a test result from an assay when contacted with a sample includes a non-planar optics module to align the assay in an offset testing position. A modular interface assembly may support a motherboard and at least one non-planar optics module. | 2022-09-15 |
20220291134 | METHOD OF PERFORMING AN ANALYTICAL MEASUREMENT - A method of performing an analytical measurement based on a color formation reaction in an optical test strip by using a mobile device having a camera. An optical test strip having a test field is provided. The camera captures a first image of at least part of the test field before a sample is applied and a second image after the sample is applied. The mobile device indicates where to take the second image so that the first and second images are taken at similar local positions with respect to at least one environmental feature that has a fixed and/or unchanged position between the capturing of the first and second images. An analytical measurement result value is then determined by using the first and second images. A computer program, a computer-readable storage medium, a mobile device and a kit for performing an analytical measurement are also disclosed. | 2022-09-15 |
20220291135 | DEVICE AND METHOD FOR MONITORING THE DRYING/CURING PROCESS OF COATINGS - Described herein is a device for monitoring and drying and/or curing process of a coating composition applied at least partially onto at least one surface of a substrate, the device including a movable skid that includes at least one substrate holding unit, at least one lamp, at least one pattern holder including a pattern, and at least one camera, where the substrate holding unit, lamp and pattern holder are positioned on the skid relative to each other such that the light of the lamp can illuminate the pattern of the pattern holder, and the illumination can be projected onto the surface of the substrate, which is held by the substrate holding unit, and where the camera is positioned on the skid relative to the substrate holding unit holding the substrate, such that the camera is capable of recording images of the light reflected off the surface of the substrate. | 2022-09-15 |
20220291136 | DEFECTIVE PART RECOGNITION DEVICE AND DEFECTIVE PART RECOGNITION METHOD - A defective part recognition device includes a microscope for obtaining a magnified image of a unit area for recognizing a defective part on the surface of a multi-layer film substrate; a spectral camera having an imaging surface where the magnified image is formed; and an information processing part for processing the spectrum information from the spectral camera. The information processing part includes a machine learning part for a clustering process on the spectrum information for each pixel, and a defect recognition part for recognizing a defective part from the result of the machine learning part. The machine learning part sets a cluster in the unit area and generates a histogram with a frequency, the number of pixels clustered into the cluster. The defect recognition part compares the frequency distribution of the generated histogram with that of a histogram free of defects and recognizes a defective part. | 2022-09-15 |
20220291137 | SURFACE INSPECTION APPARATUS - A surface inspection apparatus includes an imaging device that images a portion of an object to be inspected, a first light source that is included in multiple light sources that illuminate the portion and that is configured such that a light component that is included in light emitted from the first light source and that is reflected by specular reflection from the portion to be inspected is a principal light component that is incident on the imaging device, and a second light source that is included in the multiple light sources and that is disposed opposite the first light source with an optical axis of the imaging device interposed therebetween such that a light component that is reflected by diffuse reflection from the portion to be inspected is a principal light component that is incident on the imaging device. | 2022-09-15 |
20220291138 | METHOD OF EXAMINING SPECIMENS AND SYSTEM THEREOF - A system, method and computer readable medium for examining a specimen, the method comprising: obtaining defects of interest (DOIs) and false alarms (FAs) from a review subset selected from a group of potential defects received from an inspection tool, each potential defect is associated with attribute values defining a location of the potential defect in an attribute space; generating a representative subset of the group, comprising potential defects selected in accordance with a distribution of the potential defects within the attribute space, and indicating the potential defects in the representative subset as FA; and training a classifier using data informative of the attribute values of the DOIs, the potential defects of the representative subset, and respective indications thereof as DOIs or FAs, wherein the trained classifier is to be applied to at least some of the potential defects to obtain an estimation of a number of expected DOIs. | 2022-09-15 |
20220291139 | FOREIGN OBJECT DEBRIS DETECTION - Methods and systems are provided for foreign object debris monitoring in an environment with a dynamic debris field, such as an environment for operating an aircraft. The debris monitoring technique includes generating a light beam and dispersing it to create a virtual witness plate, which is a two-dimensional sheet of light that covers a detection area. The technique also include detecting scattered light from the virtual witness plate caused by debris passing through it. A debris event may be generated based on the scattered light, indicating the presence of debris in the detection area. | 2022-09-15 |
20220291140 | DEFECT INSPECTION DEVICE AND DEFECT INSPECTION METHOD - A defect inspection device includes an illumination unit that irradiates a sample with a linear illumination spot; a condensing detection unit that condenses reflected light of the illumination spot from the sample; and a sensor unit that forms an optical image on a light reception surface, and outputs the optical image as an electrical signal. An angle α formed between an optical axis of the condensing detection unit and a longitudinal direction of the linear illumination spot is 10° or more and less than 80°. The sensor unit is a line sensor provided with an array-like light reception unit at a position conjugate with the illumination spot. An angle β formed between direction of the line sensor and the optical axis of the condensing detection unit is 10° or more and less than 80°, and has a difference from the angle α of 5° or more. | 2022-09-15 |
20220291141 | DEFECTIVE PRODUCT DETERMINATION METHOD FOR VEHICLE WHEEL, NON-TRANSITORY STORAGE MEDIUM, AND DEFECTIVE PRODUCT DETERMINATION DEVICE FOR VEHICLE WHEEL - A defective product determination method for a vehicle wheel includes: locating, as a locating step by a controller, a lowest point on a welding mark due to radiation of a laser beam within a target range from an inner peripheral surface of a wheel rim to a position spaced away by a specified distance inward in a radial direction of the vehicle wheel; and determining, as a determination step by the controller, that the vehicle wheel is a defective product when a defective product determination condition is satisfied. The defective product determination condition includes, as a necessary condition, a condition that a relative distance of the lowest point with respect to the inner peripheral surface of the wheel rim in the radial direction of the vehicle wheel is equal to or smaller than a reference distance. | 2022-09-15 |
20220291142 | CHARACTERIZATION OF HIGH-SPEED ELECTRO-OPTIC DEVICES WITHOUT OPTICAL COUPLERS OR INTEGRATED DETECTORS - Methods, systems, and devices for testing an electro-optic device such as a modulator or a switch are disclosed. In one implementation, an apparatus includes an optical source to generate light, a first light transmission structure to route the light into the electro-optic device through a first guide segment structured to guide optical waves and optically couplable to the electro-optic device, an electrical probe to apply one or more electrical modulation signals to the electro-optic device to generate modulated light by modulating the light routed into the electro-optic device, a second light transmission structure to collect at least part of the modulated light from a second guide segment structured to guide optical waves and optically couplable to the electro-optic device, a detector to generate an electrical output signal corresponding to the collected light, and a signal processing device to record times at which each photon corresponding to the collected light is detected by processing the electrical output signal. | 2022-09-15 |
20220291143 | OPTICAL METROLOGY UTILIZING SHORT-WAVE INFRARED WAVELENGTHS - An optical metrology tool may include one or more illumination sources to generate illumination having wavelengths both within a short-wave infrared (SWIR) spectral range and outside the SWIR spectral range, illumination optics configured to direct the illumination to a sample, a first imaging channel including a first detector configured to image the sample based on a first wavelength range including at least some wavelengths in the SWIR spectral range, a second imaging channel including a second detector configured to image the sample based on a second wavelength range including at least some wavelengths outside the SWIR spectral range, and a controller. The controller may receive first images of the sample from the first detector, receive second images of the sample from the second detector, and generate an optical metrology measurement of the sample based on the first and second images. | 2022-09-15 |
20220291144 | FOREIGN MATTER INSPECTION APPARATUS, FOREIGN MATTER INSPECTION METHOD, PROCESSING APPARATUS, AND ARTICLE MANUFACTURING METHOD - A inspection apparatus for detecting a foreign matter on a substrate on which a pattern is formed includes a detection unit including a light projector for projecting light on a surface of the substrate and a light receiver, a change mechanism for changing an area of the light projected by the light projector to a first area and a second area that is smaller than the first area without changing a light amount, and a control unit for detecting the foreign matter based on a first light amount received by the light receiver in a case where the light is projected in the first area on the surface of the substrate and a second light amount received by the light receiver in a case where the light is projected in the second area on the surface of the substrate. | 2022-09-15 |
20220291145 | METHOD FOR CHARACTERIZING DEFECTS IN SILICON CRYSTAL - The present application provides a method for characterizing defects in silicon crystal comprising the following steps: etching a surface of the silicon crystal to remove a predicted thickness of the silicon crystal; conducting a LLS scanning to a surface of the etched silicon crystal to obtain a LLS map of the surface, a LSE size of defects, and defect bulk density; based on at least one of the LLS map of the surface, the LSE size of defects and the defect bulk density, determining a type of defect existing in the silicon crystal and/or a defect zone of each type of defect on the surface. By applying the method, the characterizing period and the characterizing cost can be reduced, plural defects such as vacancy, oxygen precipitate and dislocation can be characterized simultaneously, the characterizing accuracy can be enhanced, and the defect type and the defect zone can be determined with high reliability. In addition, the method can be applied to all crystal defect types, is easy to operate, and is an environmentally friendly method for determination of grown-in defects. | 2022-09-15 |
20220291146 | X-Ray Detector and Method of Manufacturing Window Portion - A window portion has a membrane that separates a space inside a container and a space outside the container, and a structure (glass structure) that is bonded to the membrane to support the membrane. The membrane and the structure are bonded by anodic bonding, and a chemical bonding layer is formed between them. The structure is composed of a grid having a plurality of openings, and an outer frame around the grid. A metal layer may be provided between the membrane and the structure. | 2022-09-15 |
20220291147 | INSPECTION POSITION IDENTIFICATION METHOD, THREE-DIMENSIONAL IMAGE GENERATION METHOD, AND INSPECTION DEVICE - An inspection position identification method that allows accurate inspection to be performed without in-advance identification of the position of an inspection plane in an inspected target. A three-dimensional image generation method that allows generation of a three-dimensional image for inspection without in-advance identification of the position of an inspection plane in an inspected target and then allows inspection to be performed. An inspection device including the methods. An inspection device includes a storage unit, which stores a radiation transmission image of an inspected object and a three-dimensional image generated from the radiation transmission image, and a control unit. The process carried out by the control unit for identifying an inspection position in a three-dimensional image includes identifying the position of a transmission picture of the inspection position in the radiation transmission image and identifying the inspection position in the three-dimensional image from the position of the transmission picture. | 2022-09-15 |
20220291148 | X-RAY AUTOMATED CALIBRATION AND MONITORING - A scanner comprises an electromagnetic wave source; a collimator positioned to alter the electromagnetic waves emitted from the electromagnetic wave source into an electromagnetic beam; and a detector positioned to measure one or more levels of electromagnetic energy of the electromagnetic beam, wherein a collimator element is spatially adjustable in at least one axis via one or more adjusting mechanisms to change the one or more levels of electromagnetic energy measured the detector. | 2022-09-15 |
20220291149 | METHOD OF INSPECTING SURFACE AND SURFACE INSPECTION APPARATUS - The present invention provides a method of inspecting a surface including detecting a presence or absence of a defect derived from a surface irregularity part of a planar inspection object to be conveyed in a predetermined direction, using a change in intensity of inspection light, the inspection light including at least two inspection lights that are parallel to a surface of the inspection object in a side view of the inspection object and pass over the surface of the inspection object or through the inspection object in a direction intersecting the conveyance direction in a plan view of the inspection object, the two inspection lights being non-parallel to each other in the plan view. | 2022-09-15 |
20220291150 | IMAGE ACQUISITION SYSTEM AND IMAGE ACQUISITION METHOD - An image acquisition system includes a radiation source configured to output radiation toward an object, a rotating stage configured to rotate the object around a rotation axis, a radiation camera having an input surface to which the radiation transmitted through the object is input and an image sensor capable of TDI control, and an image processing apparatus configured to generate a radiographic image of the object at an imaging plane P based on the image data. The angle formed between the rotation axis of the rotating stage and the input surface of the radiation camera is set in accordance with the FOD which is the distance between the radiation source and an imaging plane in the object. The radiation camera is configured to perform TDI control in the image sensor in synchronization with the rotational speed of the object rotated by the rotating stage. | 2022-09-15 |
20220291151 | Inspection Method and Associated Apparatus - Method of inspecting hazardous area equipment ( | 2022-09-15 |
20220291152 | INSPECTION METHOD AND INSPECTION DEVICE FOR MEMBRANE ELECTRODE ASSEMBLY - An inspection method of a membrane electrode assembly includes a first process of acquiring an X-ray transmission image of the membrane electrode assembly, a second process of identifying a luminance-reduced region having a luminance lower than a luminance of a surrounding region in the X-ray transmission image acquired in the first process, a third process of correcting the luminance of the luminance-reduced region identified in the second process, in accordance with a planar size of the luminance-reduced region, based on a correlation between a planar size of a foreign matter in the membrane electrode assembly and change in luminance due to diffraction of X-rays, and a fourth process of finding a thickness of the foreign matter in the membrane electrode assembly based on the luminance corrected in the third process. | 2022-09-15 |
20220291153 | ORIENTATION DEGREE DISTRIBUTION CALCULATION METHOD, ORIENTATION DEGREE DISTRIBUTION ANALYZER, AND ORIENTATION DEGREE DISTRIBUTION ANALYSIS PROGRAM - An orientation degree distribution analysis method of the present invention includes steps of: inputting crystal structure information of an object to be measured, information on an intensity ratio of each diffraction peak and a crystal plane corresponding to each diffraction peak by X-ray diffraction measurement, information on a diffraction range and diffraction sensitivity, and an intensity ratio of each diffraction peak of a randomly oriented sample to a main storage device; calculating an angle formed by an orientation plane and a crystal plane corresponding to the diffraction peak of interest from the information stored in the main storage device in the step; calculating an existence ratio and storing the existence ratio in the main storage device; setting an orientation degree distribution function; and calculating an orientation degree distribution from the information of the input step and the calculation step. As a result, there are provided a method of easily calculating an orientation degree distribution from an X-ray diffraction profile by using an information processing apparatus and a calculation program without requiring complicated pretreatment of a sample as in an EBSD method, and a method of obtaining a spatial map of the orientation degree distribution from a plurality of diffraction intensity maps obtained by using a micro-focal X-ray. | 2022-09-15 |
20220291154 | METHOD FOR IDENTIFYING THE LITHOLOGICAL LAYER OF AN EXCAVATED MATERIAL FOR THE PURPOSE OF ITS VALORISATION - A method for quickly and reliably identifying the lithological layer of an excavated material, which includes the steps of: a) analysing a specimen of the excavated material using X-ray fluorescence spectroscopy to determine the mass concentration of each of the inorganic chemical elements contained in the specimen, step a) being performed on n different surfaces of the specimen in order to determine n mass concentrations of each of the inorganic chemical elements contained in the specimen, with n being a whole number greater than or equal to 2, b) calculating the mean of the n mass concentrations of each of the inorganic chemical elements contained in the specimen and the standard deviation of this mean, c) classifying each of the inorganic chemical elements contained in the excavated material according to certain criteria for the mean n mass concentration, and d) identifying the lithological layer of the excavated material based on the classification performed during step c). | 2022-09-15 |
20220291155 | HARD X-RAY PHOTOELECTRON SPECTROSCOPY APPARATUS | 2022-09-15 |
20220291156 | METHOD FOR NUCLEAR MAGNETIC RESONANCE DIFFUSION MEASUREMENTS - A method and system for determining a property of a substance using nuclear magnetic resonance (NMR) is described herein. The method includes applying a NMR pulse sequence to the substance. The NMR pulse sequence includes a first set of pulses and a second set of pulses. The first set of pulses and the second set of pulses encode for overlapping diffusion times. By overlapping diffusion times, the NMR pulse sequence can be used to measure a diffusion coefficient for a first diffusion time, a diffusion coefficient for a second diffusion time, and a correlation between the two overlapping diffusion times. This information, in turn, can be used to differentiate between intrinsic bulk diffusivity of the substance and the reduced diffusivity of the substance caused by restricted diffusion. | 2022-09-15 |
20220291157 | METHOD FOR ESTABLISHING MATHEMATICAL MODEL OF RELATIONSHIP BETWEEN SPONTANEOUS IMBIBITION VOLUME AND TIME OF POROUS MEDIUM - A method for establishing mathematical model of relationship between spontaneous imbibition volume and time of porous medium includes sample pretreatment, fully-saturation and centrifugal experiments and NMR T | 2022-09-15 |
20220291158 | THERMAL SENSOR CHIP - The thermal sensor chip includes a substrate in which a cavity having an opening is formed, a membrane provided on a surface of the substrate so as to cover the opening, and a heater provided on or inside the membrane, wherein the heater includes wires in a mesh form constituted by a conductive member. | 2022-09-15 |
20220291159 | WIRING STRUCTURE, CONDUCTIVE PARTICLE DETECTING DEVICE, AND SPEED REDUCER - A wiring structure includes a wiring such as a flexible printed wiring board, a permanent magnet, and a relay piece. The wiring has a conductive portion. The permanent magnet has electrical conductivity. The relay piece is formed of a conductive metal and connected to the conductive portion of the wiring. The relay piece has the permanent magnet fixed thereto by magnetic attraction. | 2022-09-15 |
20220291160 | GAS SENSOR AND METHOD FOR PRODUCING ALKALINE EARTH FERRITE - The gas sensor is provided with: a base material; a first electrode and a second electrode arranged on the base material; and a gas detection member connected to the first electrode and the second electrode, wherein the gas detection member contains flaky particles of alkaline earth ferrite. | 2022-09-15 |
20220291161 | SYSTEM AND METHOD FOR MEASURING VOID FRACTION OF INSIDE OF HEAT CONDUCTION MEMBER - A system and a method for measuring a void fraction of an inside of a heat conduction member are provided. The system is used to measure the heat conduction member and includes: a heating device configured as a heat source to heat an evaporation end of the heat conduction member; a cooling device configured for cooling a condensation end of the heat conduction member; at least one pair of electrode pads respectively attached to two opposite surfaces of the heat conduction member; and an LCR meter electrically connected to the at least one pair of the electrode pads for measuring impedances of the heat conduction member. Each of the impedances is converted into the void fraction that corresponds to a measured position of the heat conduction member. | 2022-09-15 |
20220291162 | DEVICE FOR ELECTROCHEMICAL MEASUREMENTS - The invention relates to a device for electrochemical measurements comprising an electrolytic fluid vessel characterized in that tire electrolytic fluid vessel ( | 2022-09-15 |
20220291164 | IMPROVED SOLID-STATE MAGNESIUM ION SELECTIVE MICROELECTRODE AND METHODS OF PRODUCTION AND USE THEREOF - A magnesium sensing membrane is disclosed for use in a potentiometric ion selective microelectrode that exhibits an increased lower detection limit. Potentiometric ion selective microelectrodes containing said magnesium sensing membranes are also disclosed. Kits containing the microelectrodes are also disclosed, along with methods of production and use of the magnesium sensing membranes and/or potentiometric ion selective microelectrodes. | 2022-09-15 |
20220291165 | FLUID SENSOR MODULE - A fluid sensor device can include a housing having an inlet and an outlet. The housing can have a fluid reservoir, a sensing assembly, a plunger, a valve, and a plurality of channels. The fluid sensor module can be used to sense constituents in a sample fluid (e.g. patient's blood or dialysate) during a treatment process, such as kidney dialysis procedures. The fluid sensor module can be connected in-line to a medical device to sense the sample fluid. | 2022-09-15 |
20220291166 | SYSTEM AND METHOD FOR PRESENTING LARGE DNA MOLECULES FOR ANALYSIS - Systems and methods for presenting nucleic acid molecules for analysis are provided. The nucleic acid molecules have a central portion that is contained within a nanoslit. The nanoslit contains an ionic buffer. The nucleic acid molecule has a contour length that is greater than a nanoslit length of the nanoslit. An ionic strength of the ionic buffer and electrostatic or hydrodynamic properties of the nanoslit and the nucleic acid molecule combining to provide a summed Debye length that is greater than or equal to the smallest physical dimension of the nanoslit. | 2022-09-15 |
20220291167 | ION MOBILITY SEPARATION DEVICE - A method of separating ions according to their ion mobility using an ion mobility separation device including a first section and a second section is disclosed, comprising: urging ions through the first section against a first opposing electric field using a first driving force provided by a first set of time varying voltage(s) or voltage waveform(s); progressively reducing the magnitude of the first opposing electric field and/or progressively increasing the magnitude of the first driving force; and driving ions through the second section against a second opposing electric field using a second drive force provided by a second set of time-varying voltage(s) or voltage waveform(s); wherein the magnitude of the second opposing electric field is progressively reduced and/or the magnitude of the second driving force is progressively increased in tandem with reducing the magnitude of the first opposing electric field and/or increasing the magnitude of the first driving force. | 2022-09-15 |
20220291168 | SYSTEM FOR INSPECTING EQUIPMENT AND MATERIALS FOR QUALITY - Disclosed herein is a system for inspecting equipment and materials for quality. The system for inspecting equipment and materials for quality includes: a magnetic sensor configured to generate a magnetic field in an inspection target object, and to detect magnetic flux density; and a quality inspection server configured to determine the presence of a defect, a portion where the detect is present, and the type of defect for the inspection target object based on magnetic flux density waveforms over a range from one end of the inspection target object to the other end thereof that are generated via signals detected by the magnetic sensor. | 2022-09-15 |
20220291169 | MANAGEMENT DEVICE, MANAGEMENT METHOD, MANAGEMENT PROGRAM, AND RECORDING MEDIUM - A management device includes: an acquisition unit that acquires inspection result data indicating an inspection result of each of a plurality of workpieces and processing condition data indicating a processing condition used for processing each of the plurality of workpieces; an analysis unit that selects a specific parameter correlated with the inspection result among a plurality of processing parameters; and a prediction unit that predicts predict whether or not the processing device will become abnormal in future based on a temporal change in a value of the specific parameter. | 2022-09-15 |
20220291170 | COLLAPSIBLE PIPELINE INSPECTION TOOL - An in-line inspection (ILI) tool | 2022-09-15 |
20220291171 | INTEGRATED THERMOCOUPLE WAVEGUIDE SENSOR SYSTEM AND METHOD TO MEASURE PHYSICAL PROPERTIES OF WAVEGUIDE MATERIAL AND SURROUNDINGS - The present invention discloses an integrated thermocouple waveguide sensor system comprise one or more of compatible wave propagation mediums joined at one junction with at least one ultrasonic energy transducer on at least one open end of one or more wave guides and a method using the integrated thermocouple waveguide sensor system with arrangement of at least one waveguide thermocouple for integrated measurement of multiple and simultaneous physical properties of the waveguide material itself and that of the surrounding media using the Seebeck phenomena and the ultrasonic guided wave phenomena. The surrounding media properties and waveguide material properties are measured based on the ultrasonic waveguide parameters and the temperature is measured by the thermocouple. | 2022-09-15 |
20220291172 | AFFINITY SENSOR, IN PARTICULAR QCM SENSOR - An aspect of the invention pertains to an affinity biosensor for sensing an analyte (a biomolecule) in a fluid, comprising an interface for contacting the fluid and adsorption of the analyte. The interface comprises a binary pattern of nanoscale regions having affinity for the analyte and a passivated region. The nanoscale regions are isolated from one another by the passivated region in such a way that adsorption of the analyte on the interface is confined to the nanoscale regions. The nanoscale regions have diameters comprised in the range from 5 to 200 nm. The nanoscale regions have together a surface area amounting to at least 15% of the surface area of the interface. A further aspect of the invention relates to a method of using such a sensor. | 2022-09-15 |
20220291173 | INSPECTION DEVICE AND INSPECTION METHOD - According to one embodiment, an inspection device includes a transmitter configured to transmit a first ultrasonic wave, a receiver on which the first ultrasonic wave is incident, and a receiving-side waveguide located between the receiver and an inspection position. The receiver is configured to output a signal corresponding to the incident first ultrasonic wave. The inspection position is between the transmitter and the receiver. The first ultrasonic wave passes through the receiving-side waveguide. An inspection object passes through the inspection position along a second direction crossing a first direction. The first direction is from the transmitter toward the receiver. The receiving-side waveguide includes at least one of a first structure or a second structure. In the first structure, the receiving-side waveguide includes a tubular member and an inner member. The inner member is located inside the tubular member. In the second structure, the receiving-side waveguide includes a tubular member. | 2022-09-15 |
20220291174 | SONIC INSPECTION DEVICE, SONIC INSPECTION METHOD, AND CONTACT MEMBER - A sonic inspection device of an embodiment includes: a sonic probe which includes a vibrator having at least one of functions of transmitting a sound wave and of receiving a sound wave and which has a sonic function surface functioning as at least one of surfaces for transmitting the sound wave and for receiving the sound wave; a contact member including a couplant and a sheet member, the couplant being in contact with the sonic function surface of the sonic probe directly or through an intermediate member and containing at least an elastomer, and the sheet member being in contact with the couplant and having a plurality of holes; and a loading mechanism which applies/removes a load to/from the contact member. The sheet member has a thickness of not less than 0.15 times nor more than 0.35 times a wavelength λ of the sound wave propagated in the couplant. | 2022-09-15 |
20220291175 | ACOUSTIC RESONANCE DIAGNOSTIC METHOD FOR DETECTING STRUCTURAL DEGRADATION AND SYSTEM APPLYING THE SAME - An acoustic resonance diagnostic method for detecting structural degradation is provided. The method includes steps as follows: Firstly, a training model is built using a deep neural network. At least two training acoustic signals are inputted to the training model to carry a training. A diagnostic model is built according to a result of the training using a CNN. A plurality of under-test sound wave signals are captured from an under-test section of an under-test structure. An AI is used to filter data invalid for detecting structural degradation from the under-test sound wave signals. A structural degradation state of the under-test section is determined according to a remaining portion of the under-test sound wave signals through the diagnostic model. | 2022-09-15 |
20220291176 | ULTRASONIC TRANSMISSION DEVICE AND WAVE CONTROL METHOD - The present disclosure relates to an ultrasonic transmission apparatus and a wave control method, and more particularly, to an ultrasonic transmission apparatus and a wave control method which enable an ultrasonic wave to transmit through an obstacle. | 2022-09-15 |
20220291177 | APPARATUS AND METHODS FOR DETECTING AND QUANTIFYING ANALYTES - Methods and apparatuses for rapid detection and quantification of analytes are disclosed. The analytes may be opioids such as fentanyl. The method includes the use of an internal standard. The internal standard is introduced into the unknown sample. The method may involve a separation step prior to an electrochemical detection step. In some embodiments, the separation step is omitted. The analyte may be selectively adsorbed onto a surface of an electrode by maintaining a potential on the electrode during which a solution containing the dissolved analyte flows through the electrode. Performing electroanalysis on the analyte-adsorbed electrode detects and quantifies only the adsorbed analyte. In some embodiments, the internal standard is methyl vanillate. | 2022-09-15 |
20220291178 | AUTOSAMPLER - A needle driver moves a sampling needle. A display controller displays a layout input portion for receiving input of layout information in regard to an additional sample container in a display unit. A position information acquirer acquires position information representing positions of a predetermined count of containing portions in an additional sample container based on teaching work. A storage stores the input layout information and the acquired position information. A designation information acquirer acquires designation information designating a containing portion. A movement controller controls the needle driver based on the stored layout information, the stored position information and the acquired designation information such that the sampling needle is moved to the containing portion designated by the designation information. | 2022-09-15 |
20220291179 | Method for Simultaneous Determination of Nitrogen And Oxygen Isotope Compositions of Natural Nitrate and Nitrite - The disclosure describes a method for simultaneous determination of nitrogen and oxygen isotope compositions of natural nitrate and nitrite, which quantitatively converts natural nitrate and nitrite into an organic ester and a nitro-compounds respectively, and then nitrate and nitrite δ | 2022-09-15 |
20220291180 | FURAN CONCENTRATION QUANTIFYING METHOD, TRANSFORMER DETERIORATION DIAGNOSIS METHOD USING SAME, AND APPARATUS THEREFOR - Disclosed is a method of quantifying furan concentration to efficiently manage a deterioration state of a transformer in the field. The method of quantifying furan concentration includes: measuring a color-development degree of an extraction solution by making the extraction solution containing furan extracted from an insulating-oil sample mix and react with a color reagent; and quantifying furan concentration by correction based on a correlation between a precise analysis and a simple analysis with regard to the color-development degree of the extraction solution, wherein the precise analysis is to obtain a quantitative value through color column separation based on high performance liquid chromatography (HPLC) in a laboratory to analyze a furan compound in insulating oil of a transformer, and the simple analysis is to obtain a chromaticity value in a field with regard to actual transformer samples. | 2022-09-15 |
20220291181 | METHOD FOR RAPIDLY DETERMINING GRADE OF BLACK TEA - A method for determining a grade of black tea by HPLC detection belongs to the field of tea grade determination. The specific steps are as follows: adding known black tea powder samples of different grades into boiling water of 95-100° C. for extraction, and filtering with a filter membrane with a pore size in a range of 0.20-0.25 μm to obtain black tea sample liquid; measuring contents of ten components by peak area normalization method; standardizing data of the contents of the ten components in a black tea sample solution; carrying out unsupervised principal component analysis; carrying out supervised partial least squares discriminant analysis; carrying out hierarchical clustering analysis on the basis of partial least squares discriminant analysis, and finally establishing a tea grade discrimination model based on HPLC. The method is simple, accurate and efficient, and whose effectiveness is not affected by the variety of black tea. | 2022-09-15 |
20220291182 | UNIVERSAL ODOR CODE SYSTEMS AND ODOR ENCODING DEVICES - A universal odor code system encodes an olfactory stimulus into olfactory receptor space as quantitative measures of responses by olfactory receptors, producing an odor code profile. A mapping function maps an odor code profile into a formula of elements that approximates or recreates an odor code profile of a target olfactory stimulus. | 2022-09-15 |
20220291183 | Spatially Varied Plasmonic-Photonic Sensor for Detection and Identification of Airborne Agents - An odor-localizing autonomous air vehicle includes an airborne robotic platform having a navigation platform, a wireless transmitter communicatively coupled to a management console, and an olfactory sensor mounted on the airborne robotic platform that reacts to at least one olfactory odor. A controller is communicatively coupled to the airborne robotic platform, the navigation platform, and the biological sensor. The controller monitors the olfactory sensor. In response to the biological sensor detecting the at least one olfactory odor, the controller directs the airborne platform to three-dimensionally map an olfactory plume of the at least one olfactory odor using an olfactory-driven search pattern. The controller stores the three-dimensional map for later retrieval or transmits the three-dimensional map of the olfactory plume to the management console via the wireless transmitter. The olfactory sensor is a photonic crystal enclosure that contains plasmonic nanoparticles. | 2022-09-15 |
20220291184 | METHOD FOR DETECTING ANOMALIES IN ENVIRONMENTAL DATA - A method for assessing environmental data is described. The method includes receiving sensor data associated with each of a plurality of time intervals from at least one sensor on at least one mobile sensor platform. The sensor data is associated with position data corresponding to each of the plurality of time intervals. The position data corresponds to a plurality of positions having a characteristic distance not exceeding one hundred meters. The sensor data includes a plurality of measurements for each of the plurality of positions. The method includes determining, based on the sensor data and the position data, anomalous data including least one of a geographic anomaly or a temporal anomaly. | 2022-09-15 |
20220291185 | HUMIDIFICATION TYPE HIGHLY-SENSITIVE/HIGHLY-SELECTIVE AMMONIA DETECTION METHOD AND DETECTION DEVICE USING NANOMECHANICAL SENSOR - An object of the present invention is to detect ammonia with high sensitivity and high selectivity using a nanomechanical sensor with a structure that is as simple as possible. A method for detecting ammonia according to an embodiment of the present invention comprises supplying a sample gas possibly containing ammonia to a nanomechanical sensor that detects a stress or a displacement using poly(methyl vinyl ether-alt-maleic anhydride) as a material of a receptor layer, and detecting presence or absence of ammonia or a content of ammonia in the sample gas based on an output signal from the nanomechanical sensor, in which the sample gas is a humidified sample gas with controlled relative humidity. | 2022-09-15 |
20220291186 | PROCESS FOR ANALYZING DATA OF AT LEAST ONE MOBILE GAS MEASURING DEVICE AND OF A STATIONARY GAS MEASURING DEVICE AS WELL AS SYSTEM FOR MONITORING AT LEAST ONE GAS CONCENTRATION - A process and a system analyze data of at least one mobile gas measuring device as well as of a stationary gas measuring device ( | 2022-09-15 |
20220291187 | METHOD FOR DISCRIMINATING VERTICAL DISTRIBUTION MODELS OF ORGANIC CARBONS, TERMINAL DEVICE AND NON-TRANSITORY COMPUTER READABLE STORAGE MEDIUM - A method for discriminating vertical distribution models of organic carbons is provided, the method includes: obtaining a concentration of organic carbons in a surface layer of the ocean water area, depths of water of the ocean water area and depths of mixed layers of the ocean water area; determining different vertical distribution models of organic carbons in the ocean water area according to the concentration of the organic carbons in the surface layer and the depths of water of the ocean water area; calculating ratios of the depths of water of the ocean water area to the depths of the mixed layers of the ocean water area; and discriminating the vertical distribution models according to the ratios. According to this method, the accuracy of estimation of the stock of organic carbons in the ocean water area can be improved greatly. | 2022-09-15 |
20220291188 | CONDUCTIVE PARTICLE DETECTING DEVICE AND MECHANICAL DEVICE - A conductive particle detecting device includes a plurality of electrodes, a permanent magnet, and a detecting circuit. The plurality of electrodes are arranged at intervals in a lubricant. The permanent magnet accumulates conductive particles in the lubricant between adjacent electrodes by a magnetic force. The detecting circuit detects target conductive particles based on electrical resistance between the adjacent electrodes. An attractive force of the permanent magnet acting on the conductive particles between the adjacent electrodes is set such that the lubricant remains as a non-conductive layer around fine-sized conductive particles having a smaller particle size than the target conductive particles. | 2022-09-15 |
20220291189 | SAMPLE-COLLECTING DEVICE CAPABLE OF QUANTITATIVE SAMPLING - The present specification discloses a sample-collecting device capable of quantitative sampling. The sample-collecting device according to the present specification comprises an upper housing and a lower housing which are coupled to be engaged with each other. A film part and a light diffusion part may be provided between the upper housing and the lower housing. A pillar-shaped sample inlet having a central path may be formed in the upper surface of the upper housing, and a sample stopper may be formed as a step on the lower surface of the upper housing. The step is spaced apart by a predetermined distance from a hole in the central path, which is formed in the lower surface of the upper housing, to form a sample storage space, and the step is in contact with the film part to enable sealing so that a sample that has flowed into the sample storage space does not flow out between the sample stopper and the film part. | 2022-09-15 |
20220291190 | SYSTEM FOR IMAGING CAPTURED CELLS - A system for imaging captured cells comprising: an illumination module configured to illuminate a target object; a platform configured to position the target object in relation to the illumination module; a filter module configured to filter light transmitted to the target object and/or to filter light received from the target object, an optical sensor configured to receive light from the target object and to generate image data; and a focusing and optics module configured to manipulate light transmitted to the optical sensor. The system can further comprise one or more of: a control system configured to control at least one of the illumination module, the platform, the focusing and optics module, the filter module, and the optical sensor; a tag identifying system configured to identify and communicate tag information from system elements; a thermal control module configured to adjust temperature parameters of the system; and an image stabilization module. | 2022-09-15 |
20220291191 | LABEL-FREE MONITORING OF EXCITATION-CONTRACTION COUPLING AND EXCITABLE CELLS USING IMPEDANCE BASED SYSTEMS WITH MILLISECOND TIME RESOLUTION - A method for monitoring a cell beating parameter, which includes adding excitable cells capable of beating to a system for monitoring cell-substrate impedance, the system having an electrode array electrically coupled to an impedance analyzer that measures cell-substrate impedance at millisecond time resolution, and a software program that determines a cell beating parameter from measured cell-substrate impedance; monitoring cell-substrate impedance of the excitable cells; and determining the cell beating parameter from the monitored cell-substrate impedance. | 2022-09-15 |
20220291192 | INTERFACE FOR AUTOMATED FLUID INJECTION - A consumable device used in a nanopore based sequencing system can include a nanopore chip, a flow cell with one or more flow channels, and a flow cell cover. A fluidic interface can be used to deliver fluid to the flow cell. The fluid interface can include a flow cell boss and the flow cell cover can include a receptacle for receiving the flow cell boss. A dispense tip can be used to introduce fluid into the flow cell through the flow cell boss. | 2022-09-15 |
20220291193 | SMALL APERTURE LARGE ELECTRODE CELL - A nanopore cell includes a conductive layer and a working electrode disposed above the conductive layer and at the bottom of a well into which an electrolyte may be contained, such that at least a portion of a top base surface area of the working electrode is exposed to the electrolyte. The nanopore cell further includes a first insulating wall disposed above the working electrode and surrounding a lower section of a well, and a second insulating wall disposed above the first insulating wall and surrounding an upper section of the well, forming an overhang above the lower section of the well. The upper section of the well includes an opening that a membrane may span across, and wherein a base surface area of the opening is smaller than the at least a portion of the top base surface area of the working electrode that is exposed to the electrolyte. | 2022-09-15 |
20220291194 | NANOPORE STRUCTURE AND BASE SEQUENCE ANALYZER HAVING NANOPORE STRUCTURE - A nanopore structure in an embodiment according to the present invention includes a first metal member having a thin film structure and a through hole, and a second metal member arranged to narrow a diameter of the through hole. The first metal member and the second metal member form a nanopore having a pore diameter of 10 nm or less. | 2022-09-15 |
20220291195 | MICROCHIP - Providing a microchip that effectively suppresses the peeling of a bonded substrate that has been bonded together and that is unlikely to leak liquid. A microchip includes: a bonded substrate that includes a plurality of substrates, each of the substrates having a main surface and a side surface, the main surfaces being bonded each other; and a microchannel located inside the bonded substrate. The substrates include a first substrate with a large thickness and a remaining substrate with a smaller thickness than the first substrate. At least the first substrate has a side surface having a gradient and extending to an outermost side of the bonded substrate when one end of the bonded substrate is viewed from a direction parallel to the main surface. | 2022-09-15 |
20220291196 | TARGET CELL STATISTICAL METHOD, APPARATUS, AND SYSTEM - A target cell statistical method, apparatus and system are provided. A cell image of a blood specimen is acquired by a cell image analysis apparatus. The blood specimen is derived from a blood sample to be tested. A number of target cells and a number of reference cells in the cell image are automatically identified by the cell image analysis apparatus. A number of reference cells in the blood sample to be tested is acquired by the cell image analysis apparatus, and a number of target cells in the blood sample to be tested is calculated by the cell image analysis apparatus, based on the number of target cells and the number of reference cells in the cell image and the number of reference cells in the blood sample to be tested. | 2022-09-15 |
20220291197 | RAPID TESTING MECHANISM AND METHOD FOR RESPIRATORY VIRAL PATHOGENS - A rapid testing mechanism for respiratory viral pathogens includes a filter material positioned to capture exhaled breath particles from a respiratory tract. A portion of the filter material is impregnated with a pathogen binding adsorptive reagent. When the exhaled breath particles pass through the filter material the following occurs: when the binding adsorptive reagent reacts, a positive test for respiratory viral pathogens is indicated by the filter material; and when pathogen binding adsorptive reagent does not react, a negative test for respiratory viral pathogens is indicated by the filter material. | 2022-09-15 |
20220291198 | CHEMICAL SENSORS WITH NON-COVALENT, ELECTROSTATIC SURFACE MODIFICATION OF GRAPHENE - Embodiments include chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is provided. The medical device can include a graphene varactor, including a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through electrostatic interactions between a partial positive charge on hydrogen atoms of one or more hydrocarbons of the self-assembled monolayer and a π-electron system of graphene. The self-assembled monolayer can include one or more substituted porphyrins or substituted metalloporphyrins, or derivatives thereof. Other embodiments are also included herein. | 2022-09-15 |
20220291199 | ANALYSIS METHOD AND ANALYZER - Disclosed is an analysis method for analyzing a specimen containing cells, the analysis method including: applying light to a measurement sample prepared from the specimen and detecting light generated from cells; obtaining, with respect to each of a plurality of cells contained in the specimen, feature data of the cell on the basis of the detected light; analyzing the feature data with use of an artificial intelligence algorithm, thereby classifying each of the cells into a plurality of cell types; and displaying information based on a result of the classifying. | 2022-09-15 |
20220291200 | ANALYSIS METHOD AND ANALYZER - Disclosed is an analysis method for analyzing a specimen containing cells, the analysis method including: applying light to a measurement sample prepared from the specimen and detecting light generated from cells; obtaining, with respect to each of a plurality of cells contained in the specimen, feature data of the cell on the basis of the detected light; analyzing the feature data with use of an artificial intelligence algorithm, thereby classifying each of the cells into a plurality of cell types; and generating result data including a result of the classifying of each of the cells into the plurality of cell types. | 2022-09-15 |
20220291201 | ORGAN MODELS - This document provides materials and methods for making and using functional (e.g., vascularized) organ models (e.g., pancreas models). For example, functional pancreas models including an ECM containing a plurality (e.g., two or more) of pancreatic islets, and a vascular network are provided. | 2022-09-15 |
20220291202 | HIGH THROUGHPUT METHOD FOR CONSTRUCTING AND SCREENING COMPOUND LIBRARY AND REACTION DEVICE - The present invention provides a high throughput method for constructing and screening a compound library and a reaction device. Specifically, the method of the present invention comprises: (a) providing a reactor comprising n independent and addressable reaction chambers; (b) performing m independent synthesis reactions in said n reaction chambers, thereby constructing a compound library; and (c) performing activity tests in reaction chambers in which synthesis reactions are performed. In the present invention, the preparation and screening processes of a compound can be completed in the same reaction system. As the reactions of the present invention almost quantitatively generate products, the products can be directly used in enzymatic or even cytological activity test experiments without separation. | 2022-09-15 |
20220291203 | METHODS OF MEASURING CELL-MEDIATED KILLING BY EFFECTORS - The disclosure provides for compositions, methods, and kits for evaluating the effect of a cell-killing agent on a population of tumor cells (e.g., tumor cells that can inducibly express reporter protein). | 2022-09-15 |
20220291204 | METHOD FOR ACQUIRING INFORMATION ON SPINAL MUSCULAR ATROPHY - Disclosed is a method for acquiring information on spinal muscular atrophy, comprising acquiring a fluorescence image of a nucleated cell in a measurement sample, wherein the measurement sample is a sample prepared from a blood specimen obtained from a subject, an SMN protein in the nucleated cell is labeled with a first fluorescent dye, and a predetermined nuclear protein in the nucleated cell is labeled with a second fluorescent dye, acquiring an intracellular distance between a first bright spot corresponding to the first fluorescent dye and a second bright spot corresponding to the second fluorescent dye in the fluorescence image, and acquiring a value regarding a number of nucleated cells in which the intracellular distance is equal to or less than a first threshold value, wherein the value is an indicator of spinal muscular atrophy affection. | 2022-09-15 |
20220291205 | LATERAL FLOW BODILY FLUID TESTING SYSTEM AND METHOD - A lateral flow bodily fluid testing system is provided. The system comprises an application-analysable bodily fluid testing equipment ( | 2022-09-15 |
20220291206 | BODY FLUID TESTER - The present invention relates to a body fluid tester and, more specifically, to a body fluid tester wherein body fluid is collected on a test sheet, the test sheet is mounted in a carrier, and the carrier can be easily separated from a body of the tester. A body fluid tester according to an embodiment of the present invention comprises: a carrier including a sheet insertion hole into which a test sheet, on which body fluid is collected, is inserted in a first horizontal direction; an outer case including a carrier hole which is formed through the front surface thereof and extends, by a predetermined length, in a second horizontal direction intersecting with the first horizontal direction and into which the carrier is inserted, and having an open lower surface; an inner case inserted upwards through the lower surface of the outer case to be coupled to same so as to be positioned on an inner surface of the outer case, and including a case observation hole formed through the bottom surface thereof; and a lens unit positioned between the carrier and the case observation hole, wherein the carrier can be inserted into the carrier hole of the outer case or be detached from the carrier hole. | 2022-09-15 |
20220291207 | HIGH-BRIGHTNESS FLUOROPHORES FOR QUANTIFICATION AND PHENOTYPING OF EXTRACELLULAR VESICLES - A compound includes a nanomaterial carrier, a first linker having a first end connected to the nanomaterial carrier, a second linker having a second end connected to the nanomaterial carrier, a fluorescent entity connected to a second end of the first linker, and a biomolecule connected to a second end of the second linker. The biomolecule is configured to connect to a cluster of differentiation (CD) of an extracellular vesicle (EV). A method is also disclosed. | 2022-09-15 |
20220291208 | Method for Detecting Aflatoxin B1 Based on Fluorescent Copper Nanoparticles - Disclosed is a method for detecting aflatoxin B1 based on fluorescent copper nanoparticles, belonging to the technical fields of analytical chemistry, materials science and nano biosensing. In the disclosure, β-CD@DNA-Cu NMs are prepared by using Y-shaped DNA as a template, ascorbic acid as a reducing agent and β-CD as a fluorescence stabilizing and enhancing agent. Then, a ratiometric fluorescent probe is constructed based on the β-CD@DNA-Cu NMs. Finally, the detection of AFB1 with high sensitivity, high selectivity and high accuracy is achieved by using the fluorescent probe. According to the method of the disclosure, in linear ranges of 0.03-10 ppb and 10-18 ppb, a ratio value of I | 2022-09-15 |
20220291209 | MOLECULAR TARGET IN CANCER - Disclosed are methods for identifying small molecule modulators of protein-RNA interactions that could potentially function as therapeutic agents in cancer treatment. Methods of identifying inhibitors of the RNA-binding functions of MSI2, as well as inhibitors identified thereof, are also disclosed. | 2022-09-15 |
20220291210 | ANALYSIS METHOD AND ANALYSIS DEVICE - Provided is a high-accuracy analysis method utilizing an enzyme-lined immunoassay. The presence of an analyte | 2022-09-15 |
20220291211 | MICROFLUIDIC MICROPARTICLE-LABELED IMPEDANCE SENSOR ARRAY FOR ENHANCING BIOASSAY SENSITIVITY - Described herein are devices and methods for improved detection and quantitation of biomolecules. Devices and methods may include a microfluidic biosensing platform for measuring electrical impedance changes in the presence of target analytes from sinusoidal input voltages to improve the sensitivity of immunoassays. In one embodiment, the described devices and methods may provide a point-of-care immunoassay platform for quantitative diagnostics using signal-enhancing microparticles to improve sensitivity and the limit-of-detection. | 2022-09-15 |
20220291212 | DETECTION UNITS AND METHODS FOR DETECTING A TARGET ANALYTE - The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the first probe is coupled to a detectable piece, the target is coupled to the first probe and the second probe, and the second probe is coupled to a solid support. Specific binding of the detectable piece to the target analyte can be distinguished from non-specific binding of the detectable piece by measuring the number of detectable pieces that leave their initial location after exposure to a disruptor that uncouples the detectable piece from the solid support. | 2022-09-15 |
20220291213 | LATERAL FLOW DEVICES AND METHODS - Provided herein are devices, systems, and methods for purification of sample components. In particular, provided herein are lateral flow devices, systems, and methods that utilize flow control of sample handling. | 2022-09-15 |
20220291214 | Apparatus and Method for Testing the Health Condition of Animals and/or Human Beings - An apparatus and a method for undertaking a test on a person or animal on site. The apparatus includes a body having a portion for contact with a sample obtained from a person/or animal and analysis means, typically one or more biomarkers, to allow the test to be analyzed. Indication means can be provided on the apparatus to illustrate the test result on site and/or the test results can be captured and transmitted to a remote location for subsequent analysis. If deemed required after the analysis, one or more actions to be taken can be recommended to a person who has been tested and/or the person performing the test while at the location of the test and thereby allow rapid testing and actions to be performed if required. | 2022-09-15 |
20220291215 | METHODS OF IDENTIFYING T CELL RECEPTORS - The present disclosure is directed to methods of identifying MHC class II-specific T cell receptors (TCRs). In certain aspects, the method comprises contacting a T cell with a complex comprising an (i) MHC class II molecule having a higher affinity for CD4 than naturally occurring MHC class II molecules and (ii) a peptide, e.g., an epitope. In certain aspects, the HLA class II molecule comprises a beta chain having one or more mutations relative to a wild-type beta chain sequence. | 2022-09-15 |
20220291216 | PHARMACEUTICALS AND METHODS FOR TREATING HYPOXIA AND SCREENING METHODS THEREFOR - Light-generating fusion proteins having a ligand binding site and a light-generating polypeptide moiety and their use as diagnostics, in drug screening and discovery, and as therapeutics, are disclosed. The light-generating fusion protein has a feature where the bioluminescence of the polypeptide moiety changes upon binding of a ligand at the ligand binding site. The ligand may be, for example, an enzyme present in an environment only under certain conditions, e.g., ubiquitin ligase in a hypoxic state, such that the light-generating fusion protein is “turned on” only under such conditions. | 2022-09-15 |
20220291217 | GASTRIC CANCER MARKER AND EXAMINATION METHOD USING SAME - Exosomes were purified from the sera of patients with gastric cancer and healthy subjects by using size-exclusion chromatography, and novel markers were obtained through mass spectrometry. In the patients with gastric cancer, 40 proteins with enhanced expression and 4 proteins with decreased expression can be suitable markers for detecting gastric cancer. Particularly, the detailed analysis of CA1, including its function, showed that gastric cancer could be detected with high sensitivity. | 2022-09-15 |
20220291218 | METHOD OF IMPROVING EFFICACY OF MELANOMA TREATMENT - Provided are compositions and methods for determining whether or not an individual who has cancer is likely to develop immune-related adverse events (irAEs) because of treatment with an immune checkpoint inhibitor such as an anti-Programmed cell death protein 1 (anti-PD-1) checkpoint inhibitor, and/or anti-Cytotoxic T-lymphocyte-associated protein 4 (anti-CTLA-4) checkpoint inhibitor. Also provided are methods for treating an individual who has cancer with a checkpoint inhibitor and an agent to reduce the risk of toxicity from the checkpoint inhibitor, as well as administering agents to prevent or reduce the risk of toxicity during treatment. | 2022-09-15 |
20220291219 | SYSTEMS AND COMPOSITIONS FOR DIAGNOSING BARRETT'S ESOPHAGUS AND METHODS OF USING THE SAME - The invention provides a system, composition, and methods of using the systems and compositions for the analysis of a sample from a subject to accurately diagnose, prognose, or classify the subject with certain grades of or susceptibility to Barrett's esophagus. In some embodiments, the system of the present invention comprises a means of detecting and/or quantifying morphological features, the expression of protein, or the expression of nucleic acids in a plurality of cells and correlating that data with a subject's medical history to predict clinical outcome, treatment plans, preventive medicine plans, or effective therapies. In some embodiments, the invention relates to a method of classifying and compiling data taken from a cell sample from a subject analyzing the data, and converting the data from the system into a score by which a pathologist may calculate the likelihood that the subject develops cancer. | 2022-09-15 |
20220291220 | METHODS AND COMPOSITIONS FOR DETECTION AND TREATMENT OF LUNG CANCER - Disclosed herein are methods for detecting whether a subject is at risk of lung cancer based on a blood-based multivariate gene expression classifier. Methods for determining whether to obtain a biopsy in a subject based on a blood-based multivariate gene expression classifier are also disclosed. Further disclosed are methods for treating lung cancer based on a blood-based multivariate gene expression classifier are disclosed. Kits for detecting the expression levels of biomarkers for determining whether a subject is at risk of lung cancer are also disclosed. | 2022-09-15 |
20220291221 | METHOD FOR THE DETECTION OF PROSTATE CANCER - The invention relates to a body fluid test method for the detection and treatment of prostate cancer, in particular aggressive prostate cancer. It also relates to monitoring of patients with low risk prostate tumours and selection of patients for prostate biopsy as well as selection of patients for prostate surgery or therapy. | 2022-09-15 |
20220291222 | EXTRACELLULAR VESICLE BIOMARKERS FOR PANCREATIC CANCER DETECTION, DIAGNOSIS AND MONITORING - Methods and products for the identification and detection of new pancreatic cancer biomarkers based on proteins in biofluids, such as plasma and serum extracellular vesicles. | 2022-09-15 |