38th week of 2015 patent applcation highlights part 34 |
Patent application number | Title | Published |
20150260639 | SELF-CLEANING OPTICAL PROBE - An optical probe comprising an elongate hollow body having an internal chamber for receiving an optical sensor and/or an light emission device, such as one or more optical fibres, an optical window being provided at a first end of the hollow body, said optical window defining a wall of said internal chamber for transmitting light therethrough, and an ultrasonic transducer provided at a second end of the elongate body opposite said first end for cleaning said optical window via ultrasonic vibrations, wherein said ultrasonic transducer is provided with an entry aperture extending through the ultrasonic transducer, through which entry aperture optical fibres, cables or wires may pass to enter said internal chamber. | 2015-09-17 |
20150260640 | Method and System for Optical Evaluation, and Optical Detector - An optical detector comprises a plurality of pixels, each pixel comprising a photodiode operable to detect light incident on that pixel and to generate a signal indicative of an intensity of that light. The plurality of pixels comprises a plurality of pixel pairs, and for each pixel pair, in a configuration mode, the detector is arranged to compare the signal generated by a first pixel of the pair with the signal generated by a second pixel of the pair. A method of optical detection is also described, as is a system incorporating the described optical detector. | 2015-09-17 |
20150260641 | APPARATUS AND METHOD OF INVESTIGATING SURFACE PROPERTIES - The invention relates to an apparatus for the investigation of surface properties with a housing, a light source which directs light through an opening in the housing onto a surface to be investigated, with a first detector device which is arranged inside at a first pre-set angle with respect to the light beam radiated onto the surface by the light source, with a second detector device which is arranged at a second pre-set angle with respect to the light beam radiated onto the surface by the light source and with a third detector device which is arranged inside the housing at a third pre-set angle with respect to the light beam radiated onto the surface by the light source. According to the invention the apparatus has at least two filter elements with optical properties which are different from each other which are arranged on a common carrier movable with respect to the light source, in such a way that each of these filter elements is optionally capable of being brought into a beam path between the light source and the surface. | 2015-09-17 |
20150260642 | MINIATURIZED MULTIWELL PLATE READER FOR PHENOTYPIC SCREENING - A multi-well plate reader including an emitter assembly having a plurality of emitters and a receptor assembly including a plurality of receptors separated by at least one spacer element such that a multi-well plate can be inserted between the emitter assembly and the receptor assembly. The emitters and receptors are paired and arranged in parallel arrays such that electromagnetic radiation can be transmitted through each well of the multi-well plate to a corresponding receptor to determine the opacity of the biological material contained within the well. Each well of the multi-well plate can be evaluated by a different emitter receptor pair allowing the entire multi-well plate to be efficiently monitored at a high throughput. | 2015-09-17 |
20150260643 | Interactive Variable Pathlength Device - This disclosure relates generally to a sampling device, and more particularly, a sampling device that facilitates spectroscopic measurements with a variable path length and the necessary software controlled algorithms and methods for such a device. | 2015-09-17 |
20150260644 | FOODSTUFF ANALYSIS DEVICE - Provided is a foodstuff analysis device capable of readily calculating calories or component weights. The foodstuff analysis device has a light-emitting unit, a light-receiving section, and a control unit. The light-emitting unit irradiates light including at least some wavelengths among wavelengths in the range 700-1,100 nm, on to an analysis target. The light-receiving section receives light reflected from the analysis target. The control unit calculates the absorbance of light received by the light-receiving section, and calculates the calories of the analysis target on the basis of the calculated absorbance and on the basis of the correlation between absorbance and calories. | 2015-09-17 |
20150260645 | APPARATUS AND METHOD FOR MEASURING CONCENTRATION OF HEMOGLOBIN USING PHOTOTHERMAL EFFECT - The present invention relates to an apparatus for measuring concentration of hemoglobin in blood using a photothermal effect, the apparatus including: a reference light source unit for radiating a reference beam; a photothermal light source unit for radiating a photothermal beam from which the photothermal effect is generated; a cuvette unit for accommodating a collected blood sample thereinto and having first and second reflection layers; and a concentration operation unit for calculating the concentration of hemoglobin by using the phase changes of interference signals generated from the incidence of the reference beam radiated from the reference light source unit onto the first and second reflection layers of the cuvette unit as the photothermal beam radiated from the photothermal light source unit is incident onto the cuvette unit and absorbed by hemoglobin to generate the photothermal effect through the emission of heat. | 2015-09-17 |
20150260646 | LASER GAS ANALYZER - A laser gas analyzer includes a wavelength-variable laser having a wide wavelength-variable width, a light-split module configured to split an output light of the wavelength-variable laser into a measurement light and a reference light, a first gas cell into which gases to be measured are introduced, and the measurement light is made to be incident, and a data processor configured to obtain an absorption spectrum of each of the gases to be measured based on a reference signal related to the reference light and an absorption signal related to an output light of the first gas cell, and to obtain concentrations of the respective gases to be measured. | 2015-09-17 |
20150260647 | MEASUREMENT APPARATUS AND MEASUREMENT METHOD - A sensor unit photoelectrically converts received light to output image data. A lens unit condenses light reflected by an object surface to be measured on the sensor unit. A lens control unit controls a geometric condition of rays passing through the lens unit. The sensor unit and the lens control unit are controlled to acquire a multi-angular reflectance property in a neighborhood of a specular reflection direction of the object surface. | 2015-09-17 |
20150260648 | SYSTEM AND METHOD FOR HAZE MEASUREMENT - The present invention is directed to an apparatus and method for measuring the haze value of transmissive samples. The apparatus comprises a first light source selectively configurable to emit a first light beam, a second light source selectively configurable to emit a second light beam, an integrating sphere having an outer surface and an inner surface, the inner surface configured to reflect light incident upon the inner surface, the inner surface further enclosing an interior volume. The integrating sphere is further equipped with an exit port configured to emit light from the interior volume of the integrating sphere. The exit port is positioned such that light from the first light source exits the integrating sphere without obstruction, and light from the second light source is diffused on the interior surface of the integrating sphere prior to exiting the exit port. A light detector is also included and is configured to generate a light-intensity signal when light exiting the integrating sphere has passed through a sample and is incident on the light detector. The apparatus further includes a processor configured to receive the light-intensity signal and generate an output signal to a user indicating the haze value. The present invention is also directed to a method of calculating the haze value of a sample using a stored calibration value, a diffuse transmission value (sample-absent diffuse light-intensity value), a direct transmission value (sample-absent direct light-intensity value), a measured diffuse transmission value (sample-present diffuse light-intensity value) and a measured direct transmission value (sample-present direct light-intensity value). | 2015-09-17 |
20150260649 | SPR Sensor Cell and SPR Sensor - There are provided an SPR sensor cell and sensor, both having very excellent detection sensitivity. The SPR sensor cell includes: an under-cladding layer; a core layer, at least a part of the core layer being adjacent to the under-cladding layer; and a metal layer covering the core layer. The core layer includes a uniform layer and a gradient layer arranged between the uniform layer and the under-cladding layer; a refractive index N | 2015-09-17 |
20150260650 | SYSTEM AND METHOD FOR MAKING CONCENTRATION MEASUREMENTS WITHIN A SAMPLE MATERIAL USING ORBITAL ANGULAR MOMENTUM - Signal generation circuitry generates a first signal having at least one orbital angular momentum applied thereto and applies the first signal to the sample. A detector for receives the first signal after it passes through the sample and determines the concentration of the material within the sample based on a detected value of orbital angular momentum with the first signal received from the sample. | 2015-09-17 |
20150260651 | DEVICE AND METHOD FOR MEASURING CONCENTRATION OF ETCHANT - A device and method for measuring concentration of etchant, the device comprises a concentration measuring mechanism and an acid mist elimination mechanism connected with the concentration measuring mechanism, the acid mist elimination mechanism is configured to eliminate acid mist inside the concentration measuring mechanism, and the concentration measuring mechanism is configured to receive etchant in real time, measure absorbance of each kind of acid of the etchant in a non-acid mist environment, and calculate concentration of each kind of acid of the etchant according to the absorbance. It can overcome the interference of the acid mist on concentration measurement of the acid of the acid mixture etchant. In this way, the concentration of each kind of acid of the acid mixture etchant can be online measured rapidly and accurately, and the desiccative gas can be recycled, which achieves the effect of resource conservation. | 2015-09-17 |
20150260652 | ARRANGEMENT FOR AN ANALYSIS SYSTEM, ANALYSIS SYSTEM HAVING THE ARRANGEMENT AND METHOD FOR USE OF THE ARRANGEMENT - An arrangement having a birefringent component is provided for use in spatial offset measurements and analysis systems. The birefringent optical arrangement provides different directional control of the excitation signal relative to the emission signal, so that offset between an excitation and emission location on a sample can be controlled for both or only one of the excitation signal relative to the emission signal. | 2015-09-17 |
20150260653 | SECURITY ASPECTS OF MULTIEXPONENTIAL DECAYS - At least two luminescent materials are intermingled within a security feature. The materials are selected from among a larger set of luminescent materials each having a different individual exponential decay characteristic (decay constant and initial amplitude response to the degree of excitation) for photo-luminescent emission from the respective material following excitation. The ratio of the decay constants for any two materials is greater than or equal to about 1.5. The selected materials are mixed in one of a plurality of predetermined ratios. The combined emissions from the intermingled materials appear, to an unsophisticated measuring device, to have a single exponential decay constant. Based on measurements for the decay of the combined emissions following excitation, estimates of the individual decay constants and associated initial emission amplitudes allow decoding of the particular combination of materials and/or their ratios to validate the security feature, authenticating the article. | 2015-09-17 |
20150260654 | IMMUNOASSAY METHOD UTILIZING SURFACE PLASMON - At least an embodiment addresses the problem of providing a SPR (surface plasmon resonance) or SPFS (surface plasmon-field enhanced fluorescence spectroscopy) immunoassay, which enables the measurement of whole blood, undergoes little fluctuations in measurement values, and can measure whole blood, serum and plasma in a single apparatus. At least an embodiment solves the above-mentioned problem by a SPR or SPFS immunoassay, which is an immunoassay utilizing SPR or SPFS, including an absorbance measurement step of measuring an absorbance of a sample, a mode setting step of setting a mode that corresponds to the result of the absorbance measured in the absorbance measurement step, and one or multiple step(s) for which treatment condition(s) has/have been set in accordance with the mode set in the mode setting step. | 2015-09-17 |
20150260655 | METHODS FOR MEASURING CONCENTRATIONS OF CHLORINATED SOLVENTS THROUGH RAMAN SPECTROSCOPIC OBSERVATION OF THE VIBRATIONAL MODES OF WATER - Method for determining concentration of a chlorinated solvent in a non-turbid aqueous solution sample containing the chlorinated solvent is disclosed. The method includes developing a calibration profile relating intensities of Raman returns at a predetermined Raman shift associated with O—H stretching region of water for non-turbid aqueous chlorinated solvent calibration solutions of known concentrations. Intensity of Raman return at the predetermined Raman shift associated with O—H stretching region of the non-turbid aqueous solution sample is measured and compared to the calibration profile to determine the concentration of the chlorinated solvent in the non-turbid aqueous solution sample. For turbid solution samples, a method using turbidity-corrected intensity for the solution sample is disclosed. Alternatively, for turbid solution samples, a method employing a calibration profile utilizing turbid calibration solutions is disclosed. | 2015-09-17 |
20150260656 | METHOD FOR DETECTING ANALYTES - Disclosed is a method for detecting at least one analyte in a sample, which comprises applying a variable optical filter, comprising a chemochromic material that is sensitive to the analyte, to an optical lens of a camera, an optical lens of a multi-cell photosensor and/or to a multi-cell photosensor, contacting at least part of the chemochromic material with the sample, exposing at least part of the variable optical filter to electromagnetic radiation after at least part of the chemochromic material was exposed to the sample to obtain digital data regarding the chemochromic material that was contacted with the sample and processing the digital data and comparing said digital data with a reference. | 2015-09-17 |
20150260657 | ASSAYS FOR DETECTION OF GLYCOSAMINOGLYCANS - Disclosed herein are novel methods, assays and kits useful for the diagnosis and monitoring of subjects with mucopolysaccharidoses (MPS), The methods, assays and kits are particularly useful for detecting the presence of one or more glycosaminoglycans which correlate to MPS and its severity in a variety of biological samples. | 2015-09-17 |
20150260658 | Multi-Layered Devices for Analyte Detection - A multi-layered device for detecting the presence or absence of an analyte within a test sample is described. The device includes a sensing layer and a control layer. The sensing layer is configured to support a reaction so as to exhibit a signal indicative of the presence or absence of the analyte in the test sample. The control layer is in fluid communication with and vertically adjacent to the sensing layer and includes a reagent capable of inhibiting the reaction and/or other unwanted side reactions at the sensing layer after a certain period of time by diffusive movement of the reagent from the control layer to the sensing layer. | 2015-09-17 |
20150260659 | Image Sensor, An Inspection System And A Method Of Inspecting An Article - A high sensitivity image sensor comprises an epitaxial layer of silicon that is intrinsic or lightly p doped (such as a doping level less than about 10 | 2015-09-17 |
20150260660 | APPARATUS AND METHODS FOR DETECTING DEFECTS IN VERTICAL MEMORY - Disclosed are methods and apparatus for inspecting a vertical memory stack. On an inspection tool, incident light having a first wavelength range is used to detect defects on a surface of the vertical memory stack. On the inspection tool, incident light having a second wavelength range is used to detect defects on both the surface and throughout a depth of the vertical memory stack. The defects detected using the first and second wavelength range are compared to detect defects only throughout the depth of the vertical memory stack, excluding defects on the surface, as well as to detect defects only on the surface. | 2015-09-17 |
20150260661 | Sensor and Method for Recognizing an Object Located at a Roller Track | 2015-09-17 |
20150260662 | FLUID SENSOR COMPRISING A COMPOSITE CAVITY MEMBER - A fluid sensor ( | 2015-09-17 |
20150260663 | X-RAY METHOD FOR THE MEASUREMENT, CHARACTERIZATION, AND ANALYSIS OF PERIODIC STRUCTURES - Periodic spatial patterns of x-ray illumination are used to gather information about periodic objects. The structured illumination may be created using the interaction of a coherent or partially coherent x-ray source with a beam splitting grating to create a Talbot interference pattern with periodic structure. The object having periodic structures to be measured is then placed into the structured illumination, and the ensemble of signals from the multiple illumination spots is analyzed to determine various properties of the object and its structures. Applications to x-ray absorption/transmission, small angle x-ray scattering, x-ray fluorescence, x-ray reflectance, and x-ray diffraction are all possible using the method of the invention. | 2015-09-17 |
20150260664 | METHOD FOR ANALYSIS USING X-RAY FLUORESCENCE - The present invention is a method to quantify biomarkers. The method uses an X-ray fluorescence spectrometer to perform an X-ray fluorescence analysis on the sample to obtain spectral features derived from the biomarker; and quantifying the X-ray fluorescence signal of the biomarker. | 2015-09-17 |
20150260665 | Thermal Analyzer - A thermal analyzer is provided with: a furnace tube; a sample holder; a heating furnace; a measurement chamber; and a measurement unit. The heating furnace comprises a fixing section to be fixed to the furnace tube. The furnace tube is configured to be attachable to and detachable from the heating furnace and provided with an engagement portion that is configured to be engaged with the fixing section at a variable position in the radial direction. A is configured to be detachable from the heating furnace and the furnace tube after inserting the furnace tube into the heating furnace and engaging the engagement portion of the furnace tube with the fixing section while the gap jig is interposed between the heating furnace and the furnace tube to maintain the gap between the heating furnace and the furnace tube in the radial direction to be in the predetermined distance. | 2015-09-17 |
20150260666 | METHOD FOR DETERMINING WETTABILITY - In order to determine surface wettability of a material, at least one sample of the material is placed into at least one sealed calorimeter cell. The at least one sample is brought into contact with a first wetting liquid and with a second wetting liquid at the same pressure and temperature. Heats of immersion of a surface of the at least one sample by the first and second wetting liquids are measured, then the wettability is calculated. | 2015-09-17 |
20150260667 | METHOD OF DETECTING DEFECTS IN AN OBJECT BASED ON ACTIVE THERMOGRAPHY AND A SYSTEM THEREOF - There is provided a method of detecting defects in an object based on active thermography, the method including heating a surface of the object at a plurality of localized regions thereof, selecting at least one of the localized regions as a reference region, selecting at least another one of the localized regions as a comparison region, comparing a thermal response at the comparison region to a thermal response at the reference region due to the heating, and determining whether the object has a defect based on the comparison. There is also provided a corresponding system for detecting defects in an object. | 2015-09-17 |
20150260668 | MODULAR CHEMIRESISTIVE SENSOR - The present invention relates to a modular chemiresistive sensor. In particular, a modular chemiresistive sensor for hypergolic fuel and oxidizer leak detection, carbon dioxide monitoring and detection of disease biomarkers. The sensor preferably has two gold or platinum electrodes mounted on a silicon substrate where the electrodes are connected to a power source and are separated by a gap of 0.5 to 4.0 μM. A polymer nanowire or carbon nanotube spans the gap between the electrodes and connects the electrodes electrically. The electrodes are further connected to a circuit board having a processor and data storage, where the processor can measure current and voltage values between the electrodes and compare the current and voltage values with current and voltage values stored in the data storage and assigned to particular concentrations of a pre-determined substance such as those listed above or a variety of other substances. | 2015-09-17 |
20150260669 | NON-CONTACT FLUID RESISTIVITY MEASUREMENT - According to aspects of the present disclosure, systems and methods for measuring fluid resistivity are described herein. An example system may include a non-conductive tube. The non-conductive tube may be filled with a fluid, such as a formation fluid or drilling fluid, whose resistivity needs to be determined. A transmitter may be disposed around an outer surface of the non-conductive tube. A first receiver may be disposed around the outer surface of the non-conductive tube, and a second receiver may be positioned within a bore of the non-conductive tube. The transmitter may generate a primary electromagnetic field in a fluid within the tube, which may in turn generate an eddy current and a secondary electromagnetic field. The first and second receivers may be used to identify the eddy current and the resistivity of the fluid. | 2015-09-17 |
20150260670 | SHEET RESISTANCE MEASURING METHOD - The present disclosure relates to a sheet resistance measuring method, comprising the following steps: connecting at least one to-be-measured thin film having a predetermined shape to two separate electrodes in at least one pair of electrodes; measuring the resistance between the two electrodes in each pair of electrodes; and determining the sheet resistance of the to-be-measured thin film based on the measured resistance and the shape of the corresponding to-be-measured thin film. | 2015-09-17 |
20150260671 | ELECTRICAL CONDUCTIVITY MODULE - A driving circuit for a fluid conductivity sensor includes a pulse width modulation unit, an H-bridge, first and second differential amplifiers, and an analog-to-digital converter (ADC). The pulse width modulation unit generates two opposing driving signals. The H-bridge receives the two opposing driving signals and generates two H-bridge outputs. The first differential amplifier includes first inputs connected in parallel to a shunt resistor. One of the first inputs is coupled to the two generated H-bridge outputs. The second differential amplifier includes second inputs connected in parallel with a pair of terminals having a sensor attached thereto. One of the second inputs and the pair of terminals receive a signal from the other of the two generated H-bridge outputs. The ADC receives a first output representative of a first current from the first differential amplifier; and a second output representative of a second current from the second differential amplifier. | 2015-09-17 |
20150260672 | SENSOR SYSTEM FOR DETERMINING THE MOISTURE CONTENT OF A FLUID MEDIUM FLOWING IN A MAIN FLOW DIRECTION - A sensor system for determining a moisture content of a fluid medium flowing in a main flow direction, e.g., an intake air of an internal combustion engine, includes: a sensor housing; at least one moisture sensor situated in the sensor housing for determining the moisture content of the fluid medium; at least one retaining element at least partially permeable to moisture; an inlet opening for channeling moisture into the sensor housing and to the moisture sensor; and at least one outlet opening situated separately from the inlet opening and channeling moisture from the sensor housing into the flowing fluid medium. The retaining element is situated in the sensor housing in such a way that the moisture sensor is acted upon by the moisture via the inlet opening and the retaining element. | 2015-09-17 |
20150260673 | ATMOSPHERE SENSOR AND METHOD OF PRODUCING THE SAME, AND METHOD OF PRODUCING PRINTED MATTER - An atmosphere sensor includes a detecting element configured to detect external atmospheric characteristics of the atmosphere sensor. The atmosphere sensor includes inside a case having an opening, to contain the detecting element; and a moisture permeable film located on the opening to pass external water vapor of the atmosphere sensor. The moisture permeable film is bonded to the case by a welding method. | 2015-09-17 |
20150260674 | ELECTROCHEMICAL ANALYSIS AND SIMULATION DEVICE - An electrochemical analysis and simulation device includes an input unit, a processing unit, a display unit and a power supply unit. The input unit is configured to read an executable program pre-written into a replaceable counting chip. The processing unit is electrically coupled to the input unit and configured to process an inspection signal of a sample according to the executable program to generate and inspection result. The display unit is electrically coupled to the processing unit and configured to display the inspection result. The power supply unit is electrically coupled to the processing unit and the display unit and configured to supply electric power required by the processing unit and the display unit. | 2015-09-17 |
20150260675 | INSPECTION DEVICE FOR BIOLOGICALLY DERIVED MATERIAL - An examination device for a substance of biological origin includes: a base; a placing area for placing the substance of biological origin, the placing area being on a first surface of the base; a first monitor electrode; and a second monitor electrode, wherein a shortest distance from a center of the placing area to the first monitor electrode and a shortest distance from the center of the placing area to the second monitor electrode are different. | 2015-09-17 |
20150260676 | TEST STRIP FOR BIOLOGICAL COMPONENT MEASUREMENT AND MANUFACTURING METHOD THEREOF - A test strip for biological component measurement includes a substrate. A pair of a working electrode and a counter electrode, a sensor unit that produces an electrochemical reaction with a bodily fluid of a measurement subject and produces a change in electrical characteristics, a resistance portion having an electrical resistance expressing attribute information including a sensitivity of the test strip, and a pair of wires connected to both ends of the resistance portion are provided on the substrate. The resistance portion has a plurality of narrow patterns, each having a resistivity and provided so as to be distanced from each other. An end portion of each narrow pattern is near another narrow pattern. A substantially circular pattern is provided to overlap locations where the end portions of the narrow patterns are near each other, enabling the end portions to conduct with each other. | 2015-09-17 |
20150260677 | Method For Manufacturing A Lot Of Test Sensors - Systems and methods for electrochemically oxidizing components of a test-sensor reagent prior to deposition on a test sensor comprise at least a first electrode and a second electrode for contacting the test-sensor reagent. The first electrode and the second electrode may have hollow interior portions for contacting the test-sensor reagent to produce a modified test-sensor reagent having a reduced background current. | 2015-09-17 |
20150260678 | NANOPOROUS MEMBRANE - A nanoporous membrane according to the present invention includes a support member and a polymer layer disposed on the support member and including a plurality of nano pores each having an inner wall formed of a block-structured polymer material of which the end thereof is substituted by a functional group. | 2015-09-17 |
20150260679 | METHOD FOR PERFORMING PROCESSING ON GAS SENSOR - A sensor element mainly contains an oxygen ion conductive solid electrolyte. By applying, across a first electrode formed on a surface of an internal space into which a measurement gas is introduced from an outside and a second electrode formed on an external surface of the element, a predetermined voltage determined based on a potential difference between the first electrode and a reference electrode provided inside the element, oxygen in the internal space can be pumped out. In a case where pump reference processing is performed, a DC voltage having a maximum value of 1.4 to 2.0 V inclusive is applied across the reference and second electrodes for 10 to 1200 seconds inclusive in a state in which the reference and second electrodes are respectively electrically connected to negative and positive terminals of an external DC power supply, and an element temperature is set to 700 to 850° C. inclusive. | 2015-09-17 |
20150260680 | MODIFIED PROTEINS AND METHODS OF MAKING AND USING SAME - Methods, compositions, systems, apparatuses and kits comprising modified proteins, particularly modified nucleic acid-binding proteins with altered buffering properties are provided. For example, in some embodiments, methods of forming modified proteins including one or more amino acid modifications to achieve desired pKa values are described. Furthermore, the invention provides methods for using such modified proteins in ion-producing reactions, such as ion-based nucleic acid sequencing reactions. | 2015-09-17 |
20150260681 | DIP-STICK WESTERN BLOT - Methods, kits, and systems are provided for separating, immobilizing, and/or detecting analytes of one or more samples using dipsticks. A ‘dipstick’ is an object that can be embedded and subsequently removed from a separation medium, and to which analytes can be immobilized while the object is embedded in the separation medium. Examples of separation media include an electrophoresis gel of any format and a stationary phase for column chromatography. Embodiments of the present methods include applying a sample to a separation medium; separating analytes of the sample in the separation medium along a separation axis; immobilizing the analytes on a dipstick embedded in the separation medium; removing the dipstick from the separation medium; and detecting the analytes immobilized on the removed dipstick. | 2015-09-17 |
20150260682 | MICROFLUIDIC DEVICE FOR GEL ELECTROPHORESIS AND METHOD OF MANUFACTURING THEREOF - According to embodiments of the present invention, a microfluidic device for gel electrophoresis is provided. The microfluidic device includes a sample channel configured to receive a sample; a stacking channel comprising a preloaded stacking reagent; and a separation channel comprising a preloaded separation reagent, wherein the preloaded stacking reagent has a physical characteristic different from that of the preloaded separation reagent; and wherein the sample channel, the stacking channel and the separation channel are in fluid communication with one another. According to further embodiments of the present invention, a method of manufacturing a microfluidic device for gel electrophoresis is also provided. | 2015-09-17 |
20150260683 | Mass Spectrometer - A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator and an ion guide arranged downstream of the ion mobility spectrometer or separator. A plurality of axial potential wells are created in the ion guide so that ions received from the ion mobility spectrometer or separator become confined in separate axial potential wells. The potential wells maintain the fidelity and/or composition of ions received from the ion mobility spectrometer or separator. The potential wells are translated along the length of the ion guide. | 2015-09-17 |
20150260684 | METHOD AND APPARATUS FOR ION MOBILITY SPECTROMETRY - Methods and systems for performing mass spectrometry are provided herein. The method includes ionizing one or more compounds to generate ions, passing the ions into an ion mobility spectrometer, providing ozone, reacting the ions with ozone to produce ozone-induced fragment ions, and performing mass analysis and detection of the ozone-induced fragment ions. The system can comprise an ion source for ionizing one or more compounds to generate ions, an ion mobility spectrometer for receiving and separating the ions, an ozone supply for introducing ozone into the system; a reaction region for reacting the ions with the ozone to produce ozone-induced fragment ions, and a mass spectrometer for performing mass analysis and detection of the ozone-induced fragment ions. | 2015-09-17 |
20150260685 | Method of Mapping Anomalies in Homogenous Material - An electrical conductor and antenna are positioned in a fixed relationship to one another. Relative lateral movement is generated between the electrical conductor and a homogenous material while maintaining the electrical conductor at a fixed distance from the homogenous material. The antenna supplies a time-varying magnetic field that causes the electrical conductor to resonate and generate harmonic electric and magnetic field responses. Disruptions in at least one of the electric and magnetic field responses during this lateral movement are indicative of a lateral location of a subsurface anomaly. Next, relative out--of-plane movement is generated between the electrical conductor and the homogenous material in the vicinity of the anomaly's lateral location. Disruptions in at least one of the electric and magnetic field responses during this out-of-plane movement are indicative of a depth location of the subsurface anomaly. A recording of the disruptions provides a mapping of the anomaly. | 2015-09-17 |
20150260686 | SYSTEM AND METHOD FOR TESTING SHELL AND TUBE HEAT EXCHANGERS FOR DEFECTS - A magnetostrictive transducer assembly for generating a longitudinal elastic guided wave of a selected frequency and mode and for guiding the wave into an open end of a heat exchanger tube for testing the tube. The transducer assembly comprises a current-carrying coil of wire, a magnetostrictive material wrapped around the coil of wire, a mechanism for pressing the magnetostrictive material against an inner surface of the tube, and one or more biasing magnets placed in the vicinity of the current-carrying coil of wire and the magnetostrictive material. | 2015-09-17 |
20150260687 | FLUID STATE IDENTIFICATION DEVICE - Provided is a fluid state identification device including a fluid state identification unit having a sensor part and a support part, and a cover surrounding the fluid state identification unit. The support part has a front surface part and a rear surface part which are located opposite to each other. The sensor part is located on the front surface part side. The cover has a lower opening and an upper opening. Inside the cover, a first fluid flow route running through a front area adjacent to the support front surface part and a second fluid flow route running through a rear area adjacent to the support rear surface part are formed and located so as to make the fluidity of the fluid in the second fluid flow route higher than the fluidity of the fluid in the first fluid flow route. | 2015-09-17 |
20150260688 | SHEET CONVEYING DEVICE, IMAGE FORMING APPARATUS, AND METHOD OF DETERMINING WHETHER MULTI-FEED HAS OCCURRED - A sheet conveying device includes: a sending unit configured to send an ultrasonic wave; a receiving unit positioned to face the sending unit across a conveyance path, along which a sheet is conveyed, and configured to receive a first ultrasonic wave, the first ultrasonic wave being an ultrasonic wave sent from the sending unit and passed through the sheet, and output a first voltage corresponding to the first ultrasonic wave; an adjusting unit configured to adjust the first voltage into an adjusted first voltage according to a setting; an amplification unit configured to amplify the adjusted first voltage by a preset amplification factor for multi-feed determination into an amplified first voltage; and a determining unit configured to determine whether or not multi-feed of the sheet has occurred based on the amplified first voltage. | 2015-09-17 |
20150260689 | PARTICLE ANALYSIS IN AN ACOUSTIC CYTOMETER - The present invention is a method and apparatus for acoustically manipulating one or more particles. | 2015-09-17 |
20150260690 | METHOD AND SYSTEM FOR IMMERSION ULTRASOUND INSPECTION INCLUDING WITHIN DOWNWARDLY OPENING CAVITIES - Immersion ultrasonic NDE is performed within cavities of inanimate objects, having downwardly directed openings, such as for in situ inspection of steam inlet sleeves and steam inlet necks within steam turbine housings. A shaft assembly has one or more single angle or phased array ultrasonic probes that are affixed on an upstream or distal end. An inflatable bladder is affixed to the shaft on a proximal end of the shaft assembly downstream the ultrasonic probe(s). The shaft is inserted into the cavity opening, and the bladder is inflated to form a fluid tight seal against the cavity. Immersion fluid is introduced upstream the bladder in the volume occupied by the probes. Immersion ultrasonic inspection of the object is then performed. | 2015-09-17 |
20150260691 | PHASING ADDER, ULTRASOUND PROBE, ACOUSTIC SENSOR AND ULTRASOUND DIAGNOSIS APPARATUS - Disclosed is a phasing adder including delay charge transfer units including holding and transferring units which obtain signal charge amounts that are not amplified and which send and receive the signal charge amounts across a predetermined plurality of stages while holding the signal charge amounts for a predetermined time in each stage and a delay adder which performs phasing addition of the signal charges which are held for a predetermined number of stages in the delay charge transfer unit, and electric capacity of each first holding unit, which is the first stage among the plurality of stages in the holding and transferring unit, where the signal charges are obtained and held at a time of ultrasound wave reception is greater than electric capacity of each of later holding units where the signal charges are to be held in a second stage and stages thereafter. | 2015-09-17 |
20150260692 | METHOD AND SYSTEM FOR VERIFYING THE AGE OF AN AMINAL PROVIDING MEAT - The invention provides a method for verifying the age of an animal providing meat using volatile profiles that comprises the step of providing a sample of animal meat. The method uses one or more chemical analyses to obtain a profile of a set of volatile organic compounds from a sample of meat from an animal. The profile is fit to a mathematically discriminating function resulting. The data obtained is analyzed in order to establish a correlation between the age of the animal (tooth development) and volatiles exuded by meat. | 2015-09-17 |
20150260693 | MULTI-MEASUREMENT FLOW CELL ASSEMBLY FOR LIQUID CHROMATOGRAPHY - A detector for detecting constituents of a liquid for use in liquid chromatography is disclosed. The detector includes a first optical flow cell body and a second optical flow cell body, each having a channel therethrough that allows passage of a liquid from an inlet port to an outlet port. The first and second optical flow cell bodies are arranged in series such that the liquid exiting the outlet port of the first optical flow cell body enters the inlet port of the second optical flow cell body. An insulator resides between the first optical flow cell body and the second optical flow cell body, which is adapted to electrically insulate the first optical flow cell body from the second optical flow cell body while allowing the liquid to pass from the first optical flow cell body to the second optical flow cell body. The first optical flow cell body is adapted to facilitate measurement of absorption by the liquid of a first wavelength of light, and second optical flow cell body is adapted to facilitate measurement of absorption by the liquid of a second wavelength of light. The first and second optical flow cell bodies are further adapted to perform as electrodes for measuring the conductivity of the liquid. | 2015-09-17 |
20150260694 | GAS CHROMATOGRAPHY DEVICE - A gas chromatography device includes a sample injection part, a detector, a separation column, and a transfer line connecting between the sample injection part and the separation column and between the sample injection part and the detector. Furthermore, a column temperature adjustment part for adjusting the temperature of the separation column, and a line temperature adjustment part for adjusting the temperature of the transfer line are provided. The line temperature adjustment part is structured to include a heat block which includes a heating element and which is in contact with the transfer line from one side, and a holding member which presses the transfer line toward the heat block side by being in contact from the other side, and to sandwich the transfer line by the heat block and the holding member. | 2015-09-17 |
20150260695 | PROCESS AND SYSTEM FOR RAPID SAMPLE ANALYSIS - Components resolved in time by a separator accumulate in a sample cell and are analyzed by electromagnetic radiation-based spectroscopic techniques. The sample cell can be configured for multiple path absorption and can be heated. The separator can be a gas chromatograph or another suitable device, for example a distillation-based separator. The method and system described herein can include other mechanical elements, controls, procedures for handling background and sample data, protocols for species identification and/or quantification, automation, computer interfaces, algorithms, software or other features. | 2015-09-17 |
20150260696 | METHODS FOR DETECTING AND REDUCING IMPURITIES OF LAPATINIB AND SALTS THEREOF - Impurities of lapatinib such as N-{3-chloro-4-[(2-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazoline-4-amine compound of formula (I) or a salt thereof: | 2015-09-17 |
20150260697 | METHOD FOR FITTING PROTECTION TUBE TO GAS SENSOR AND APPARATUS FOR FITTING PROTECTION TUBE TO GAS SENSOR - A method for fitting a protection tube to a gas sensor includes: a step for engaging tube-end opening jigs which have been inserted into the inside of a protection tube through its one end portion, with this end portion, for maintaining this end portion at an opened state, a step for bringing tube-end holding jigs into contact with this engagement portion from outside for holding the tube through pinching between these jigs, and a step for inserting the sensor into the inside of the tube being held through pinching, wherein the insertion of the sensor into the inside of the tube is continued even after an end portion of the sensor comes into contact with the inner surface of the tube, while the engagement of the tube with the tube-end opening jigs is gradually released, thereby fitting the tube to the sensor. | 2015-09-17 |
20150260698 | GAS SENSOR - In a gas sensor, not only a tube | 2015-09-17 |
20150260699 | DYNAMIC RECIPE CONTROL - Nutritional substance systems and methods are disclosed enabling the tracking and communication of changes in nutritional, organoleptic, and aesthetic values of nutritional substances, and further enabling the adaptive storage and adaptive conditioning of nutritional substances. | 2015-09-17 |
20150260700 | INDEX AND METHOD OF USE OF ADAPTED FOOD COMPOSITIONS FOR DYSPHAGIC PERSONS - The present invention provides a method in which a quantitative and descriptive approach is used to adapt the food texture in the clinical management of dysphagia. There is provided a new index, ST index, and method of use for determining and modulating the physical characteristics of foods in a manner to allow the food composition at serving temperature to have a desired combination of firmness, adhesiveness, springiness and cohesiveness to overcome dysphagia-related problems. | 2015-09-17 |
20150260701 | METHOD AND APPARATUS FOR SIMULTANEOUS ONLINE ASSAY OF NITRITES AND NITRATES IN WATER SAMPLES - The invention relates to an apparatus for simultaneous online assay of nitrites and nitrates in water samples with improved sensitivity and accuracy, enhanced capacity of anti-interference against salinity, reduced assay costs, and simplified operation. | 2015-09-17 |
20150260702 | SYSTEMS AND METHODS FOR CONTROLLING CATIONIC WATER TREATMENT ADDITIVES - Systems and methods are provided for measuring the amount of cationic organic water treatment additives in water systems. Disclosed systems and methods monitor, analyze and control the amounts of cationic organic water treatment additive supplied to the water. Disclosed systems and methods may include various dyes and surfactants for facilitating the monitoring and control of the cationic organic water treatment additives. | 2015-09-17 |
20150260703 | REAL TIME MEASUREMENT OF MUD LOGGING GAS ANALYSIS - Disclosed are systems and methods for measuring the gas content in drilling fluids in real time using optical computing devices. One system includes a flow path circulating a drilling fluid into and out of a borehole during drilling operations, a first optical computing device arranged at or near an outlet of the borehole and having a first integrated computational element configured to optically interact with the drilling fluid as it exits the borehole and generate a first output signal corresponding to a concentration of a gas present in the drilling fluid at the outlet of the borehole, and a signal processor communicably coupled to the first optical computing device and configured to receive the first output signal and determine the concentration of the gas present in the drilling fluid at the outlet of the borehole. | 2015-09-17 |
20150260704 | GENDER, VIABILITY AND/OR DEVELOPMENTAL STAGE DETERMINATION OF AVIAN EMBRYOS IN OVO - The present invention relates to a process for the non-destructive determination of gender, developmental stage and/or viability of an avian embryo in an egg, comprising (a) detecting at least a first developmental marker compound selected from sugars and/or amino acids, precursors and metabolites thereof in an egg at a time period of from the beginning of the incubation of the egg until the hatching; (b) measuring the amount of the at least first detected developmental marker compound, and (c) comparing the amount to a base line established for male and female, developmental stage of the embryo, and/or alive and deceased or non-developed embryo, to determine whether the embryo is viable, male and/or female, and/or the developmental stage of the embryo. | 2015-09-17 |
20150260705 | METHOD AND APPARATUS FOR MEASURING HEMATOCRIT OF BLOOD - Disclosed herein are a method and an apparatus for measuring hematocrit of flowing blood. The apparatus for measuring hematocrit of blood according to an exemplary embodiment of the present invention includes: a body part provided with a blood inlet and a blood outlet; first and second electrodes disposed on both inner side walls of the body part so as to be opposite to each other; a third electrode disposed on the same side wall as a side wall on which the first electrode is disposed while maintaining a predetermined distance from the first electrode; a measurement unit measuring first impedance of blood between the first and second electrodes and second impedance of the blood between the first and third electrodes; and a calculation unit determining the hematocrit of blood using the first and second impedances. | 2015-09-17 |
20150260706 | System and Method for Analysing and Measuring Ammonia Levels in a Sample - A system for sensing and measuring ammonia in a breath sample is described. The system comprises a sampling means for capturing and directing a breath sample from a subject to an ammonia sensor, the ammonia sensor comprising a conducting polymer polyaniline sensor. The sampling means comprises a breath sample capture chamber, the chamber having an inlet and outlet, the inlet having a first valve through which a breath is exhaled into the sample capture chamber, the outlet having a second valve through which breath surplus to the volume of the chamber is expelled, to provide capture of a breath sample of predefined volume. | 2015-09-17 |
20150260707 | METHOD FOR EVALUATING THE SCENT PERFORMANCE OF PERFUMES OR PERFUME MIXTURES - Proposed is a method for evaluating the scent performance of perfumes or perfume mixtures, wherein at least one odorants is brought into contact with an olfactory receptor selected from the group consisting of OR1B1, OR2L8, OR4X2, OR4C16, OR5L1, OR8B4, OR8D2, OR10A6, OR10C1, OR12D2, OR524, OR4E2, OR4P4, OR4K2, OR4C3, OR5I1, OR10Q1 and measuring the response of the receptor. | 2015-09-17 |
20150260708 | System and Method for Lateral Flow Immunoassay Testing - A lateral flow immunoassay system is provided that includes a housing having a base portion forming a first chamber therein and a body portion formed with three openings in fluid communication with the first chamber, a vial containing a buffer agent, and a sample collector for introducing a sample fluid into the first chamber via the second opening. The vial is mounted to the housing such that a dispensing side extends into the first opening for dispensing the buffer agent therefrom into the first chamber. The housing allows the buffer agent and sample fluid to be mixed within a reaction well formed within the first chamber to form a test sample mixture. The body portion is configured to receive a receiving end of an elongated holder in the third opening and allow a test strip secured in the holder to be brought into communication with the text sample mixture. | 2015-09-17 |
20150260709 | DIAGNOSTIC DEVICE AND DIAGNOSTIC SYSTEM HAVING THE SAME - A diagnostic device capable of measuring a concentration of glycated hemoglobin using a simple structure and a diagnostic system having the same are provided. The diagnostic device includes: a first sample supplier including a bond inhibiting substance that inhibits bonding between glycated hemoglobin and a bonding substance bound selectively to the glycated hemoglobin; a second sample supplier separated from the first sample supplier; a first chamber connected to the first sample supplier through a first passage between the first sample supplier and the first chamber; and a second chamber connected to the second sample supplier through a second passage between the second sample supplier and the second chamber. | 2015-09-17 |
20150260710 | SELECTIVE CAPTURE AND STIMULATED RELEASE OF CIRCULATING TUMOR CELLS ON NANOSTRUCTURED DEVICES - A device for capturing preselected cell types from a fluid sample that includes a plurality of cell types includes a substrate, a plurality of nanowires at least one of attached to or integral with a surface of the substrate such that each nanowire of the plurality of nanowires has an unattached end, and a layer of temperature-responsive material formed on at least the unattached end of each of the plurality of nanowires. The layer of temperature-responsive material has a compact configuration at a first temperature and an expanded configuration at a second temperature so as to facilitate release of cells captured at the first temperature to be released at the second temperature. | 2015-09-17 |
20150260711 | Microfluidic Device For Cell Separation And Uses Thereof - The invention features methods for separating cells from a sample (e.g., separating fetal red blood cells from maternal blood). The method begins with the introduction of a sample including cells into one or more microfluidic channels. In one embodiment, the device includes at least two processing steps. For example, a mixture of cells is introduced into a microfluidic channel that selectively allows the passage of a desired type of cell, and the population of cells enriched in the desired type is then introduced into a second microfluidic channel that allows the passage of the desired cell to produce a population of cells further enriched in the desired type. The selection of cells is based on a property of the cells in the mixture, for example, size, shape, deformability, surface characteristics (e.g., cell surface receptors or antigens and membrane permeability), or intracellular properties (e.g., expression of a particular enzyme). | 2015-09-17 |
20150260712 | Methods, Systems, and Arrays for Biomolecular Analysis - Disclosed herein are formulations, substrates, and arrays. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays. Also disclosed are methods for identifying peptide sequences useful for diagnosis and treatment of disorders, and methods for using the peptide sequences for diagnosis and treatment of disorders, e.g., celiac disorder. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. | 2015-09-17 |
20150260713 | QUANTIFICATION OF A CHANGE IN ASSAY - The present invention relates to portable devices for point-of-care diagnostics that can perform measurements on a sample (e.g., blood, serum, saliva, or urine) and relay data to an external device for, e.g., data analysis. The device can comprise a paper-based diagnostic substrate and a base substrate that include electronic circuitry and electronic elements necessary for performing the measurements. The device can also comprise an antenna for near field communication with an external device. Another aspect of the invention relates to methods of using these devices. | 2015-09-17 |
20150260714 | SEROLOGIC TEST FOR THE RAPID DIAGNOSIS OF ACTIVE TUBERCULOSIS - The present invention relates to methods and kits for detecting active tuberculosis infection in a subject using serological techniques and a first agent capable of binding an IgG, IgA and/or IgM directed to the first protein present in or on a | 2015-09-17 |
20150260715 | RAPID DETECTION AND QUANTITATION OF PATHOGEN-SPECIFIC BIOMARKERS USING NANOPOROUS DUAL- OR MULTI-LAYER SILICA FILMS - Improved methods for detecting active tuberculosis are disclosed. A method comprises enriching at least one | 2015-09-17 |
20150260716 | DIAGNOSIS OF TUBERCULOSIS - The invention comprises an oligonucleotide selected from the group comprising SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3; SEQ ID NO: 4; SEQ ID NO: 5 and SEQ ID NO: 6. The invention also comprises a complementary oligonucleotide of the oligonucleotide selected from the group comprising SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3; SEQ ID NO: 4; SEQ ID NO: 5 and SEQ ID NO: 6, an oligonucleotide being at least 80% homogolous thereto, a truncated portion of any of the aforementioned, or a pairing of any of the aforementioned. | 2015-09-17 |
20150260717 | UNIVERSAL NUCLEIC ACID APTAMERS FOR COMMONLY BINDING TO VARIOUS TYPES OF MICROORGANICMS AND METHOD OF PRODUCING THE SAME - Provided are a single-stranded nucleic acid aptamer simultaneously and specifically binding to various types of microorganisms, and a method of manufacturing the nucleic acid aptamer. For example, provided are a probe that is capable of simultaneously detecting or diagnosing a variety of microorganisms, and a method of manufacturing an aptamer having characteristics of such a probe. | 2015-09-17 |
20150260718 | Methods, Devices, Kits and Compositions for Detecting Roundworm, Whipworm, and Hookworm - Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm, whipworm and/or hookworm in a fecal sample from a mammal and may also be able to distinguish between one or more helminth infections. Confirmation of the presence or absence of roundworm, whipworm and/or hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated. | 2015-09-17 |
20150260719 | MICROFLUIDIC LAL-REACTIVE SUBSTANCES TESTING METHOD AND APPARATUS - A microfluidic testing cartridge for testing LAL-reactive substances in fluid samples is provided. The cartridge may comprise at least two (2) testing modules, wherein each testing module includes at least one inlet port for receiving one of the fluid samples, and at least four (4) testing channels in fluid communication with the inlet port. Each of the testing channels may include a metering portion for metering an aliquot of the fluid sample, an analyzing portion, and a mixing portion, wherein a valve is positioned between the metering portion and the analyzing portion to selectively fluidly separate the metering portion from the analyzing portion. The cartridge is insertable into an optical reader which performs optical measurements of the fluid sample within each test ing channel during a testing process. | 2015-09-17 |
20150260720 | METHOD AND KIT FOR DISTINGUISHING BETWEEN PROSTATE CARCINOMA AND BENIGN PROSTATIC HYPERPLASIA - An object of the present invention is to provide a method for distinguishing between prostate carcinoma and benign prostatic hyperplasia with high sensitivity and good reproducibility using a small amount of an analyte sample. The method for distinguishing between prostate carcinoma and benign prostatic hyperplasia according to the present invention as a solution means thereof comprises: bringing an analyte sample containing a prostate-specific antigen (PSA) into contact with a carrier having an anti-free PSA antibody immobilized thereon, thereby binding free PSA to the anti-free PSA antibody immobilized on the carrier; thereafter bringing the carrier in which the free PSA is bound to the immobilized anti-free PSA antibody into contact with a monoclonal antibody capable of specifically recognizing a glycan in which a terminal sialic acid residue is bound to galactose through an α(2,3) bond, thereby binding the monoclonal antibody capable of specifically recognizing a glycan in which a terminal sialic acid residue is bound to galactose through an α(2,3) bond to the free PSA bound to the anti-free PSA antibody immobilized on the carrier; measuring the amount of the free PSA having an N-type glycan in which a terminal sialic acid residue is bound to galactose through an α(2,3) bond; comparing the measured amount thus obtained with a preset cutoff value for prostate carcinoma and benign prostatic hyperplasia, thereby determining that when the measured amount is larger than the cutoff value, prostate carcinoma is developed or the probability of developing prostate carcinoma is high, and when the measured amount is smaller than the cutoff value, benign prostatic hyperplasia is developed or the probability of developing benign prostatic hyperplasia is high. | 2015-09-17 |
20150260721 | NOVEL BIOMARKERS FOR SUB-TYPING PANCREATIC DUCTAL ADENOCARCINOMA - This invention relates to novel approaches for the identification and stratification of subtypes of pancreatic ductal adenocarcinoma (PDAC), in particular to novel PDAC subtype-specific markers, and to diagnostic kits comprising reagents for detecting said markers. | 2015-09-17 |
20150260722 | NOVEL CANCER MARKER AND UTILIZATION THEREOF - The present invention provides a novel cancer marker that is useful in the diagnosis of urothelial cancer. The present invention uses ubiquilin 2 as a cancer marker for urothelial cancer (renal pelvis cancer, ureteral cancer, and bladder cancer). Detection of ubiquilin 2 in a urine sample allows easy and accurate diagnosis of a possibility of urothelial cancer. The present invention is also applicable to the diagnosis of squamous cancer (esophageal cancer, cervical cancer, etc.). | 2015-09-17 |
20150260723 | COMPANION DIAGNOSTICS FOR TEC FAMILY KINASE INHIBITOR THERAPY - The invention provides methods, assays and systems for determining the efficacy of a TEC family kinase inhibitor on a target kinase. The methods, assays and systems relate to determining the occupancy of a target kinase by a TEC family kinase inhibitor (e.g., BTK inhibitors). Such quantitative measurements are used to inform therapeutic treatment and the over-all health care management of a subject. For example, diagnostic kits for diagnosing, prognosing, and monitoring a disease or indication benefiting from treatment with a TEC family kinase inhibitor are provided. In another example, diagnostic kits for identifying responders to TEC family kinase inhibitor therapy, determining therapeutic regimens, and detecting resistance to TEC family kinase inhibitor also are provided. | 2015-09-17 |
20150260724 | CELL BASED SENSOR - Cell based sensor. The present invention relates to a novel cell based sensor useful for drug discovery that comprises a cell line with professional regulated exocytosis of secretory granules transfected with a non-protease hydrolase as a reporter polypeptide stored in the regulated secretory granules of the cell line with professional regulated exocytosis and having either an endogenous or a heterologous molecule as a modulator of regulated secretory granules exocytosis. Said granule stored non protease-hydrolase reporter having at least: a high resistance to conditions already present inside the granules such as low pH and proteolysis by other proteases; enzymatic activity after exocytosis; a highly specific substrate; absence of toxicity when cell thawing; a very low level of secretion under unstimulated or basal conditions; and a high signal to background activity in a media compatible with cell culture viability and granule exocytosis for a high throughput robust and sensitive detection. | 2015-09-17 |
20150260725 | CARBOXY X RHODAMINE ANALOGS - The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis and/or treatment of disease conditions. | 2015-09-17 |
20150260726 | SYSTEMS AND METHODS FOR MANAGEMENT OF MEDICAL CONDITION - Embodiments of the invention relate to a self-contained kit for medical condition monitoring and maintenance, such as the monitoring and maintenance of blood sugar levels. The kit is compact and includes components structurally retained therein for use without removal, wherein these components are normally separate and loose. Such components could include a glucose meter, an insulin pen and a lancing apparatus. Other embodiments of the invention relate to a computer system and method for monitoring a medical condition, monitoring a medical condition over time, correlating recorded results with environmental factors such as location, time and meals consumed. A method may also enable individual users to share information to provide support to one another. | 2015-09-17 |
20150260727 | Targeted Identification of Immunogenic Peptides - This invention relates generally to identifying peptide sequences involved in antibody binding to any protein for synthesis of vaccine treatments. This novel method allows for a more manageable vaccine peptide discovery and specific generation of unique immunogenic peptides from self-tumor associated proteins and/or foreign proteins from infectious organisms for specific and/or enhanced expression only in the presence of the antibody. | 2015-09-17 |
20150260728 | Method for Diagnosing a Molecular Phenotype of a Patient Suffering From an Illness Accompanied by Chronic Inflammation - Chronic inflammation is an increasing medical problem area of high socioeconomic significance. The invention relates to a method and a kit for diagnosing a molecular phenotype of a patient suffering from an illness accompanied by chronic inflammation, and to a medicament for treating such a patient. To that end, the gene expression of GATA-3 and/or Tbet in a biological isolate of the patient is measured and used for association with a molecular phenotype of the illness. | 2015-09-17 |
20150260729 | SCHIZOPHRENIA MARKER SET AND ITS UTILIZATION - The object is to provide a combination of biomarkers which allow highly accurate discrimination of schizophrenia, and a utilization thereof. A combination of schizophrenia marker set including a combination of two or more protein molecules selected from the group consisting of trifunctional purine biosynthetic protein adenosine-3, uroporphyrinogen decarboxylase, interferon-induced GTP-binding protein Mx1, glutaredoxin-3, microtubule-associated protein RP/EB family member 1, tubulin folding cofactor B, immunoglobulin mu chain C region, and heat shock 70 kDa protein 4L is provided. In addition, a method for examining schizophrenia using the level of the marker set in a specimen as an index is provided. | 2015-09-17 |
20150260730 | PROSTATITIS-ASSOCIATED ANTIGENS AND METHODS OF USE THEREOF - The present disclosure provides prostatitis-associated antigens, and compositions comprising the antigens. The present disclosure provides diagnostic methods, generally involving assaying the level of an immune response specific for a prostatitis-associated antigen in an individual. Kits suitable for use in performing such diagnostic assays are also provided. The present disclosure further provides methods of treating prostatitis, methods of treating prostate cancer, and methods of treating benign prostatic hyperplasia. | 2015-09-17 |
20150260731 | ANTIBODIES, KIT AND METHOD FOR DETECTING AMYLOID BETA OLIGOMERS - This invention is a selective Aβ oligomer kit and immunoassay method capable of reliably and sensitively detecting Aβ oligomers in a biological sample of a patient. In one embodiment the inventive assay uses a pair of anti-Aβ oligomer antibodies, as capture and detection antibodies, to detect and quantify Aβ oligomers. The method can be used to differentiate Alzheimer's disease (AD) patients from non-AD patients and/or to stratify AD patients according to the severity of their disease. | 2015-09-17 |
20150260732 | METHOD FOR DIAGNOSING OR MONITORING KIDNEY FUNCTION OR DIAGNOSING KIDNEY DYSFUNCTION - A method for (a) diagnosing or monitoring kidney function in subject or (b) diagnosing kidney dysfunction in a subject or (c) predicting or monitoring the risk of an adverse events in a diseased subject or (d) predicting or monitoring the success of a therapy or intervention comprising
| 2015-09-17 |
20150260733 | METHOD FOR IDENTIFYING COMPOUNDS THAT MODULATE A T2R TASTE RECEPTOR - The invention provides nucleic acid and amino acid sequences for a novel family of taste transduction G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste transduction G-protein coupled receptors. | 2015-09-17 |
20150260734 | NOVEL COMPOUND, AND METHOD FOR MEASURING IRON CONCENTRATION BY USING NOVEL COMPOUND AS CHELATE COLOR FORMER - The present invention addresses the problem of providing a chelate color former which can measure the concentration of iron with high sensitivity and with low blank values when measuring the concentration of iron, and an iron concentration measurement method and kit that use this chelate color former. The present invention relates to: a compound represented by following formula [1] or a salt thereof | 2015-09-17 |
20150260735 | Method for Hemostasis Testing - A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis. | 2015-09-17 |
20150260736 | METHOD FOR DETECTING MODULATORS OF GPIB-THROMBIN INTERACTION - The present invention is in the field of coagulation diagnostics and relates to methods for detecting modulators of GPIb-thrombin interaction in a sample. To this end, the sample is contacted with isolated mutated GPIbα protein and thrombin, and the formation of a complex between mutated GPIbα protein and thrombin is determined. | 2015-09-17 |
20150260737 | LIPIDOMIC BIOMARKERS FOR THE PREDICTION OF CARDIOVASCULAR OUTCOMES IN CORONARY ARTERY DISEASE PATIENTS NOT UNDERGOING STATIN TREATMENT - The present invention inter alia provides a method, and use thereof, of predicting severe CVD complications such as AMI or CVD death by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in predicting these CVD complications than currently utilized clinical markers. Also provided are antibodies towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating CVD complications. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of CVD complications. | 2015-09-17 |
20150260738 | LIPIDOMIC BIOMARKERS FOR THE PREDICTION OF CARDIOVASCULAR OUTCOMES IN CORONARY ARTERY DISEASE PATIENTS UNDERGOING STATIN TREATMENT - The present invention inter alia provides a method, and use thereof, of predicting severe CVD complications such as AMI or CVD death by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in predicting these CVD complications than currently utilized clinical markers. Also provided are antibodies towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating CVD complications. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of CVD complications. | 2015-09-17 |