39th week of 2008 patent applcation highlights part 41 |
Patent application number | Title | Published |
20080233478 | ANODE, METHOD OF MANUFACTURING IT, BATTERY, AND METHOD OF MANUFACTURING IT - A battery capable of improving the cycle characteristics and the swollenness characteristics is provided. The battery includes a cathode, an anode, and an electrolytic solution. The node has an anode current collector and an anode active material layer provided thereon, and the anode active material layer contains a plurality of anode active material particles having silicon, and a metal material having a metal element not being alloyed with an electrode reactant in a gap between the anode active material particles. | 2008-09-25 |
20080233479 | NEGATIVE ACTIVE MATERIAL FOR RECHARGEABLE LITHIUM BATTERY AND RECHARGEABLE LITHIUM BATTERY INCLUDING SAME - Negative active materials for rechargeable lithium batteries are provided. One negative active material includes at least one Si active particle and a metal matrix surrounding the Si active particle. The metal matrix does not react with the Si active particle. The negative active material has a martensite phase when X-ray diffraction intensity is measured using a CuKα ray. The negative active material has improved efficiency and cycle-life. | 2008-09-25 |
20080233480 | NEGATIVE ACTIVE MATERIAL FOR RECHARGEABLE LITHIUM BATTERY AND RECHARGEABLE LITHIUM BATTERY - Negative active materials and rechargeable lithium batteries including the negative active materials are provided. The negative active material includes an intermetallic compound of Si and a metal, and a metal matrix including Cu and Al. The negative active material may provide a rechargeable lithium battery having high capacity and excellent cycle-life and cell efficiency. | 2008-09-25 |
20080233481 | POSITIVE ELECTRODE ACTIVE MATERIAL FOR NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY - To provide a positive electrode active material for a non-aqueous electrolyte secondary battery, which can achieve high capacity and high output simultaneously, and a non-aqueous electrolyte secondary battery using the same. A non-aqueous electrolyte secondary battery is obtained by using as a positive electrode, a positive electrode active material for a non-aqueous electrolyte secondary battery, which is expressed by the general formula: Li | 2008-09-25 |
20080233482 | Lead-Tin-Silver-Bismuth Containing Alloy for Positive Grid of Lead Acid Batteries - A lead-acid battery grid made from a lead-based alloy containing, in addition to lead, tin at a concentration that is at least about 0.500%, silver at a concentration that is greater than 0.006%, and bismuth at a concentration that is at least about 0.005%, and, if calcium is present in the lead-based alloy, the calcium is at concentration that is no greater than about 0.010%. | 2008-09-25 |
20080233483 | Layer having shielded fibers; and galvanic cell - A layer, in particular for use as a separator in galvanic cells, including fibers having at least one first substance which renders possible the chemical and/or physical binding of ammonia or ammonia compounds. A galvanic cell having a low self-discharging rate over its entire life cycle having a layer wherein a first substance is present in volumetric regions of the fibers whose surface areas are at least partially covered by a second substance. | 2008-09-25 |
20080233484 | Battery with Gelled Electrolyte - An electric device comprises a gelled acid electrolyte in complex with a lanthanide that forms a redox pair with a second element. Preferred electric devices include batteries, and especially primary batteries, while preferred acid electrolytes have a sulfonic acid group. Contemplated lanthanides especially include cerium, and preferred second elements particularly include zinc. Alternatively, contemplated electric devices may comprise a gelled electrolyte in which with a lanthanide forms a redox pair with zinc. | 2008-09-25 |
20080233485 | NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY - A non-aqueous electrolyte secondary battery comprises: a positive electrode using a positive electrode active material consisting of metal composite oxide containing lithium having a laminated structure; a negative electrode; and a non-aqueous electrolyte dissolving an electrolyte in a non-aqueous solvent; wherein the positive electrode active material contains 50 mol % or more of nickel in metal excluding lithium, and cyclic ether is added in the range of 0.1 volume % to 2.0 volume % to the non-aqueous electrolyte. | 2008-09-25 |
20080233486 | System and Method for Providing Phase Shift Mask Passivation Layer - System and method for providing a passivation layer for a phase shift mask (“PSM”) are described. In one embodiment, a PSM comprises a transparent substrate; a phase shift pattern disposed on the transparent substrate; and a passivation layer disposed to substantially cover exposed surfaces of at least a portion of the phase shift pattern. | 2008-09-25 |
20080233487 | Method and System for Optimizing Lithography Focus and/or Energy Using a Specially-Designed Optical Critical Dimension Pattern - Disclosed is a method and a system for optimizing lithography focus and/or energy using a specially-designed optical critical dimension pattern. A wafer comprising a plurality of photomasks is received. Critical dimension, line-end shortening, and side wall angle of the plurality of photomasks are measured using an integrated metrology equipment. A spectrum analysis is performed in a simulated spectra library to form analysis data. The analysis data is stored into a plurality of lookup tables of an optical critical dimension library. A lookup of the plurality of lookup tables is performed to determine a focus or energy of the wafer. | 2008-09-25 |
20080233488 | Mask with hydrophobic surface - A mask with hydrophobic surface. The mask includes a substrate, a plurality of patterns formed on the substrate, and a self-assembled monolayer (SAM) formed on the substrate exposed by the patterns. The self-assembled monolayer includes an alkyltrichlorosilane-based layer such as octadecyltrichlorosilane (OTS) or perfluorodecyltrichlorosilane (FDTS) and formed by vapor process or solution process. | 2008-09-25 |
20080233489 | Method to form a pattern of functional material on a substrate using a stamp having a surface modifying material - The invention provides a method to form a pattern of functional material on a substrate. The method uses an elastomeric stamp having a relief structure with a raised surface and having a modulus of elasticity of at least 10 MegaPascal. A surface modifying material is applied to the relief structure and forms a layer at least on the raised surface. A composition of the functional material and a liquid is applied to the layer of the surface modifying material on the relief structure and the liquid is removed to form a film. The elastomeric stamp transfers the functional material from the raised surface to the substrate to form a pattern of the functional material on the substrate. The method is suitable for the fabrication of microcircuitry for electronic devices and components. | 2008-09-25 |
20080233490 | Mask rework method - A mask rework method includes forming a first carbon-containing hard mask layer and a first silicon-containing hard mask layer over an etch target layer, forming a first photoresist pattern over the first-silicon-containing hard mask layer, removing the first photoresist pattern, the first silicon-containing hard mask layer, and the first carbon-containing hard mask layer to generate a resulting structure, stacking a second carbon-containing hard mask layer and a second silicon-containing hard mask layer on the resulting structure, and forming a second photoresist pattern over the second silicon-containing hard mask layer. | 2008-09-25 |
20080233491 | BARRIER FILM MATERIAL AND PATTERN FORMATION METHOD USING THE SAME - A barrier film material includes, in addition to an alkali-soluble polymer, a multivalent carboxylic acid compound having a plurality of carboxyl groups or a multivalent alcohol compound. Thus, the multivalent carboxylic acid compound or the multivalent alcohol compound is adhered onto the surface of a resist film, and hence, particles having been adhered to the surface of the resist film are removed in removing the barrier film. Also, in the case where the barrier film is removed simultaneously with development, the resist film can be prevented from remaining partly undissolved. | 2008-09-25 |
20080233492 | METHOD OF MANUFACTURING COLOR FILTERS - The present invention provides a method of manufacturing color filters using a first mixed gas and a second mixed gas. In the method, a stopper layer whose etching rate by the second mixed gas is low is formed on the support, a colored layer is formed on the stopper layer, a photo resist layer is formed on the colored layer, an image on the colored layer is formed by removing the photo resist layer according to a pattern, a part of the colored layer is removed by dry etching process using the first mixed gas to the extent that the stopper layer is not exposed removing so as to form a colored-layer removed portion according to the pattern, and the colored-layer removed portion is removed by dry etching process using the second mixed gas so as to form a stopper-layer exposed portion according to the pattern. | 2008-09-25 |
20080233493 | PROCESSES FOR FORMING PARTITION WALLS, COLOR FILTER AND ORGANIC EL - To provide a process for forming partition walls excellent in the uniformity in thickness of the ink layer even when light exposure is low in the exposure step. | 2008-09-25 |
20080233494 | Method for forming a high resolution resist pattern on a semiconductor wafer - In one disclosed embodiment, a method for forming a high resolution resist pattern on a semiconductor wafer involves forming a layer of resist comprising, for example a polymer matrix and a catalytic species, over a material layer formed over a semiconductor wafer; exposing the layer of resist to patterned radiation; and applying a magnetic field to the semiconductor wafer during a post exposure bake process. In one embodiment, the patterned radiation is provided by an extreme ultraviolet (EUV) light source. In other embodiments, the source of patterned radiation can be an electron beam, or ion beam, for example. In one embodiment, the polymer matrix is an organic polymer matrix such as, for example, styrene, acrylate, or methacrylate. In one embodiment, the catalytic species can be, for example, an acid, a base, or an oxidizing agent. | 2008-09-25 |
20080233495 | TONER AND METHOD FOR PRODUCING THE SAME, AND, DEVELOPER, TONER-CONTAINING CONTAINER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD - A toner producing method is provided, which comprises preparing toner base particles in an aqueous medium, wherein the toner base particles comprise resin fine particles, and forming a coating layer on the surface of the toner base particles, wherein the coating layer is formed by attaching or coating a toner functional substance onto the surface of the toner base particles using at least one of supercritical fluids and sub-supercritical fluids. | 2008-09-25 |
20080233496 | TONER FOR DEVELOPING LATENT ELECTROSTATIC IMAGE, TWO-COMPONENT DEVELOPER, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS - The present invention provides a toner which, despite its spherical shape, makes it possible to prevent an external additive from being embedded in the toner easily or by a load generating low stress, reduce variation in image density, maintain cleaning ability and transfer ability throughout its long-term use and obtain excellent image quality, and further, provides a two-component developer, an image forming method and an image forming apparatus with the use of the toner. There is a toner including: base particles including a colorant and a resin, and hard fine particles, wherein the base particles and the hard fine particles are mixed together, and protruding portions formed of fine organic resin particles which are different in composition from a resin contained as a main component in the base particles are provided on surfaces of the base particles. | 2008-09-25 |
20080233497 | TONER FOR DEVELOPING LATENT ELECTROSTATIC IMAGE, PROCESS CARTRIDGE AND IMAGE FORMING METHOD - A toner for developing a latent electrostatic image produced by suspension polymerizing a polymerizable monomer composition in an aqueous dispersion medium, wherein the polymerizable monomer composition contains a polymerizable monomer, a colorant, and a layered inorganic mineral in which at least a part of an interlayer ion is replaced with an organic ion, and a process cartridge and an image forming method using the toner. | 2008-09-25 |
20080233498 | TONER, DEVELOPER, TONER CONTAINER, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS - There is provided a toner which contains at least a binder resin, and filler including a layered inorganic compound, wherein the layered inorganic compound is cleaved to form particles in the toner, and the particles have a breadth of 0.5 nm to 4 nm, and a length of 10 nm to 90 nm. | 2008-09-25 |
20080233499 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS - An electrophotographic photosensitive member having a charge generation layer containing a phenanthrene compound, a phenanthroline compound or an acenaphthene compound. Also disclosed are a process cartridge and an electrophotographic apparatus which have the electrophotographic photosensitive member. | 2008-09-25 |
20080233500 | PHOTORECEPTOR DEVICE HAVING A SELF-ASSEMBLED PATTERNED BINDER LAYER - A photoreceptor device having at least one layer that is a self-assembled patterned binder layer, which may include at least one functional material. | 2008-09-25 |
20080233501 | Photoconductors containing fluorinated components - A photoconductor containing a fluoroalkyl ester layer, a supporting substrate, a photogenerating layer, and at least one charge transport layer. | 2008-09-25 |
20080233502 | Overcoated photoconductors containing fluorinated components - A photoconductor containing an optional supporting substrate, a photogenerating layer, at least one charge transport layer, and an overcoating layer in contact with and contiguous to the charge transport layer, and which overcoating layer includes a fluoroalkyl ester, and a polymer. | 2008-09-25 |
20080233503 | Photoconductor fluorinated charge transport layers - A photoconductor containing a supporting substrate, a photogenerating layer, and at least one charge transport layer which contains a fluoroalkyl ester. | 2008-09-25 |
20080233504 | Corona detection device - A corona detection device includes a bandpass filter having a primary passband that includes at least wavelengths in the range of about 250 nm to about 400 nm and a secondary passband that includes wavelengths in the range of about 675 nm to about 850 nm. The corona detection device also includes an image intensifier in optical communication with the bandpass filter. The image intensifier is configured to generate an image based on radiation passed through the primary passband and the secondary passband of the bandpass filter. | 2008-09-25 |
20080233505 | TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGE, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE TONER - A toner, including a parent particulate material including a colorant and a binder resin, and an external additive including particles having an average primary particle diameter from 80 to less than 150 nm in an amount of from 0.03 to 2% by number, particles having an average primary particle diameter from 5 nm to less than 15 nm in an amount of from 50 to 95% by number, and particles having an average primary particle diameter from 15 to less than 40 nm in an amount of from 5 to 40% by number, and the particles having an average primary particle diameter from 80 to less than 150 nm include particles having an average primary particle diameter not less than 200 nm in an amount of from 10 to 30% by number, and have a weight reduction rate not greater than 3.00% when heated from 30 to 250° C. | 2008-09-25 |
20080233506 | TONER, AND OILLESS FIXING METHOD AND PROCESS CARTRIDGE USING THE TONER - A toner useful for an oilless fixing method, includes a binder resin; a colorant; and 2.0 to 4.5% by weight of a wax which is soluble in n-hexane, based on a total weight of the toner, wherein the wax is dispersed in the toner, the wax forming wax domain particles (DA) comprising wax domain particles (DS) exposed at a surface of the toner and wax domain particles (DI) encapsulated in the toner and not exposed at the surface of the toner, wherein a weight of the DS is greater than a weight of the DI, wherein the toner from which the DS have been eluted with n-hexane comprises vestigial concavities having an area of 0.01 πμm | 2008-09-25 |
20080233507 | TWO COMPONENT DEVELOPER - A two component developer used in an electrophotographic method composed of a toner containing at least a resin and a colorant, and a carrier, is disclosed. The resin is composed of a polyester resin and a styrene-acryl resin, in which the polyester resin is prepared via condensation-polymerization of a polyvalent carboxylic acid and a polyol in a state where a styrene monomer and an acrylate monomer exist in an aqueous medium containing an acidic compound, followed by formation of the styrene-acryl resin via radical polymerization of the styrene monomer and the acrylate monomer; and the carrier comprises magnetic material powder dispersed in a binder resin, and has a volume based median diameter of 10 μm-100 μm, a shape factor SF-1 of 1.0-1.2, and a shape factor SF-2 of 1.1-2.5. | 2008-09-25 |
20080233508 | PROCESS FOR PRODUCING TONER FOR ELECTROPHOTOGRAPHY - The present invention relates to a process for producing a toner for electrophotography, including:
| 2008-09-25 |
20080233509 | SPHERICAL SILICA CORE-SHELL PARTICLES - A process of preparing spherical nano-sized core/shell silica particles, including providing a latex polymer dispersion comprising particles of a liquid dispersible starting polymer in a dispersion liquid, adding at least one functionalized monomer to the latex polymer dispersion and polymerizing the at least one functionalized monomer on the particles, and growing an outer silicate shell on the particles through addition and reaction of at least one silane monomer. | 2008-09-25 |
20080233510 | TONER AND METHOD FOR PRODUCING THE SAME, TONER CONTAINER, DEVELOPER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE - Disclosed is a non-magnetic toner for use in developing electrostatic toner image, wherein the toner is produced by a toner production method that includes: dispersing in an aqueous medium an organic dispersion liquid that comprises in an organic solvent a pigment, a binder resin and/or a binder resin precursor, and a releasing agent; removing the organic solvent to prepare a dispersion slurry in which toner particles are dispersed in the aqueous medium; heating the dispersion slurry to a temperature equal to or higher than the melting point of the releasing agent; and washing the toner particles. | 2008-09-25 |
20080233511 | TONER, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME - A toner including particles including a toner composition including a binder resin and a coloring material, wherein the toner composition includes a laminate compound A in which a cation between layers is modified by an organic cation, and a laminate compound B in which an anion between layers is modified by an organic anion, the laminate compound A is of negative charging property upon particulation of the laminate compound A by dispersion or internal addition in the binder resin and the laminate compound B is of positive charging property upon particulation of the laminate compound B by dispersion or internal addition in the binder resin, and the toner is of a positive charging property. | 2008-09-25 |
20080233512 | Liquid recovery system, immersion exposure apparatus, immersion exposing method, and device fabricating method - A liquid recovery system is used by an immersion exposure apparatus. The liquid recovery system comprises: a plate that has a first surface and a second surface on the side opposite the first surface; and a liquid recovery part, at least part of which opposes the second surface with a first gap interposed therebetween. The liquid recovery system recovers the liquid on a movable object that opposes the first surface of the plate via the liquid recovery part. | 2008-09-25 |
20080233513 | Heat-Resistant Photosensitive Resin Composition, Method For Forming Pattern Using the Composition, and Electronic Part - A heat resistant photosensitive resin composition having excellent film properties is provided by constituting a photosensitive resin composition containing (A) a polymer having an acid functional group and/or a substituent derived therefrom, (B) a compound having at least one substituent derived from an amine functional group, (C) a photoreactive compound, and (D) a solvent. Using this composition, a pattern with high resolution can be produced, and thus an electronic part having a high quality can be produced. | 2008-09-25 |
20080233514 | POSITIVE PHOTORESIST COMPOSITION WITH A POLYMER INCLUDING A FLUOROSULFONAMIDE GROUP AND PROCESS FOR ITS USE - A positive photoresist composition comprises a radiation sensitive acid generator, and a polymer that includes a first repeating unit derived from a sulfonamide monomer including a fluorosulfonamide functionality, a second repeating unit having a pendant acid-labile moiety, and a third repeating unit having a lactone functionality. The positive photoresist composition may be used to form patterned features on a substrate, such as those used in the manufacture of a semiconductor device. | 2008-09-25 |
20080233515 | RADIATION SENSITIVE RESIN COMPOSITION FOR FORMING A PROTECTIVE FILM, METHOD OF FORMING A PROTECTIVE FILM FROM THE COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE AND SOLID-STATE IMAGE SENSING DEVICE - A radiation sensitive resin composition for forming a protective film, comprising:
| 2008-09-25 |
20080233516 | NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME - A negative lithographic printing plate precursor includes a support; and a photo-polymerization layer containing a polymer compound having at least one of a sulfonamido group and a cyclic structure derived from maleimide, and further having a hydrophilic group in a molecule thereof | 2008-09-25 |
20080233517 | Negative Resists Based on Acid-Catalyzed Elimination of Polar Molecules - The present invention provides polymers that are useful in negative resist compositions. Polymers of the present invention comprise (1) a first monomer having a polar functional group; (2) a second monomer; and optionally, (3) a third monomer that imparts at least one characteristic selected from crosslinkable functionality, etch resistance, and solubility modulation. The first monomer provides an acid catalyzed polarity switch upon elimination of the polar functional group, whereas, the second monomer provides aqueous dissolution. The polymers of the present invention may be incorporated into negative resist compositions, which may also include photoacid generators, crosslinking agents, basic compounds, solvents, dissolution accelerators, photobase generators, latent basic compounds, surfactants, adhesion promoters, and anti-foaming agents. | 2008-09-25 |
20080233518 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND MANUFACTURING METHOD OF SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE WITH SUCH CHEMICALLY AMPLIFIED RESIST COMPOSITION - With the damascene process in which an interconnection is formed using a conventional chemically amplified positive photoresist composition, there arises a problem that the photoresist within the via hole (as well as in its vicinity) may remain even after the exposure and the development are carried out. The present invention relates to a chemically amplified resist composition comprising, at least, a photo acid generator, a quencher and a salt having a buffering function for an acid which is generated from the acid generator by irradiation, wherein the salt having the buffering function for the acid generated from the acid generator is a salt derived from a long chain alkylbenzenesulfonic acid or a long chain alkoxybenzenesulfonic acid and an organic amine that is a basic compound. | 2008-09-25 |
20080233519 | METHODS FOR FABRICATING OPTICAL MICROSTRUCTURES BY IMAGING A RADIATION SENSITIVE LAYER SANDWICHED BETWEEN OUTER LAYERS - Microstructures are fabricated by imaging a microstructure master blank that includes a radiation sensitive layer sandwiched between a pair of outer layers, on an imaging platform, to define the microstructures in the radiation sensitive layer. At least one of the outer layers is then removed. The microstructures that were defined in the radiation sensitive layer are developed. The radiation sensitive layer sandwiched between the pair of outer layers may be fabricated as webs, to provide microstructure master blanks. | 2008-09-25 |
20080233520 | Method For Producing Multi-Layer Optical Disk - A method for producing a multilayer optical disk including a plurality of information storage layers is disclosed. The method includes a mastering step of preparing a plurality of metal dies, a replicating step of producing a base plate onto which a desired pattern is transferred using the plurality of metal dies and forming recordable/reproducible information storage layers. The desired pattern includes a wobbling tract pattern that is formed by combining a plurality of wobble patterns each having the same fundamental frequency. The mastering step produces the plurality of metal dies for the plurality of information storage layers having a shape that specifies a track groove whose shape factor differs from one information storage layer to another. | 2008-09-25 |
20080233521 | Method for manufacturing substrate for making microarray - A method for manufacturing a substrate for making a microarray wherein a monomolecular film for immobilizing a target molecule can be simply formed position-selectively in manufacture of the substrate for making the microarray is provided. | 2008-09-25 |
20080233522 | Method of forming 3D micro structures with high aspect ratios - A method of forming 3D micro structures with high aspect ratios includes the steps of: disposing a mask, which has a plurality of through holes having at least two different sizes, on a substrate to expose the substrate through the through holes; forming a negative photoresist layer on the mask and the substrate; providing a light source to illuminate the negative photoresist layer through the substrate and the through holes of the mask so as to form a plurality of exposed portions and an unexposed portion; and removing the unexposed portion and leaving the exposed portions to form a plurality of pillars each having a bottom portion contacting the substrate and a top portion opposite to the bottom portion. A top area of the top portion is slightly smaller than a bottom area of the bottom portion, and the pillars are allowed to have at least two different heights. | 2008-09-25 |
20080233523 | FLARE CHARACTERIZATION AND CONTROL SYSTEM - A video analytics system for characterization of a flare. A video of a flare may be taken for obtaining information so as to appropriately control the flare in an interest of reducing emissions not necessarily favorable to the environment. The system may incorporate a control scenario involving one or more parameters of a flare which are to be controlled in view of a flare characterization from an algorithmic analysis of the video. | 2008-09-25 |
20080233524 | HEAT ACCUMULATING-TYPE BURNER - A heat accumulating-type burner that operates by alternately repeating heat accumulation and combustion where the heat accumulating element is heated by exhaust gas to accumulate heat therein, and combustion air is passed through the heat accumulating portion to preheat the combustion air by thermal exchange with the heat accumulating element that holds the heat accumulated therein, and the preheated combustion air is used to carry out, combustion. The cross-sectional area of the heat accumulating portion at the furnace-inner side is made to be smaller than the cross-sectional area of the heat accumulating portion at the air supply/discharge port side, and in addition, the thickness of the fireproof heat insulating member that covers the heat accumulating portion is made to be thick at the furnace-inner side of the heat accumulating portion, and is made to be thin at the air supply/discharge port side of the heat accumulating portion. | 2008-09-25 |
20080233525 | Turbine engine having folded annular jet combustor - A combustor for a turbine engine is disclosed. The combustor may have a can-like dilution zone, a primary combustion zone, and a secondary combustion zone. The primary combustion zone may be disposed radially about the can-like dilution zone. The secondary combustion zone may be disposed at an end of the can-like dilution zone to fluidly communicate the primary combustion zone and the can-like dilution zone. | 2008-09-25 |
20080233526 | Heating Apparatus - The invention discloses a heating apparatus, which includes a housing frame consisting of conduits for containing gas and/or liquid fuel and which includes supporting means for supporting an object to be heated; burning means for heating the object supported on the supporting means; and inlet means for supplying the gas and/or liquid fuel to the burning means. The apparatus furthermore includes valve means associated with the burning means, and being adapted to prevent the supply of gas and/or liquid fuel to the burning means if the supporting means is not substantially horizontal. The apparatus furthermore includes valve means associated with the burning means, and being adapted to prevent the supply of gas and/or liquid fuel to the burning means if an object is not supported by the supporting means. | 2008-09-25 |
20080233527 | Method for continuous mixing and melting inorganic salts and furnace installation for realizing the method - The invention relates to a method for the continuous melting of inorganic salts and a furnace installation for realizing the method. Solid salts are fed into a furnace with the aid of a feeding unit. The salts contained in the furnace are heated. A flow of the salts is generating inside the furnace with the aid of a circulating unit. The flow generates a two-phase region containing solid and melted salt and a separate second region containing substantially solely a melt that is heated to the desired temperature. The melt is discharged from the separate second region simultaneous with the feeding of the solid salts into the furnace with the aid of a removal unit. | 2008-09-25 |
20080233528 | INDIRECT BONDING TRAYS FOR ORTHODONTIC TREATMENT AND METHODS FOR MAKING THE SAME - An indirect bonding tray places orthodontic appliances in precise, predetermined positions on the teeth of a patient. The indirect bonding tray includes a first matrix material that extends over a set of appliances and a second matrix material that extends over the first matrix material. The indirect bonding tray also includes at least one occlusal stop member that is connected to the second matrix material for firm, relatively hard contact with the occlusal tips of the patient's teeth when the tray is received in place over the patient's dental arch. | 2008-09-25 |
20080233529 | Active attachments for interacting with a polymeric shell dental appliance - An active dental attachment. Specifically, an attachment device for interacting with a polymeric shell dental appliance is described. The attachment device includes an anchoring attachment body. A bonding surface is coupled to the anchoring attachment body, wherein the bonding surface is configured for anchoring the anchoring attachment body to a dental feature of a patient's dentition. A force-applying active mechanism is coupled to the anchoring attachment body. A polymeric shell dental appliance contact region is coupled to the force-applying active mechanism. The polymeric shell dental appliance contact region is configured to contact the force-applying active mechanism and apply a force generated by the force-applying active mechanism between the dental feature and the polymeric shell dental appliance when the polymeric shell dental appliance engages the force-applying active mechanism. | 2008-09-25 |
20080233530 | METHODS AND APPARATUS FOR BONDING ORTHODONTIC APPLIANCES USING PHOTOCURABLE ADHESIVE MATERIAL - A bonding tray for indirect bonding of orthodontic appliances includes a body adapted to fit over at least a portion of the dental arch. One or more orthodontic appliances are releasably connected to the body, and a photocurable adhesive material extends across the base or bonding pad of each appliance for bonding the appliance to a tooth. An outer surface of the body includes at least one receptacle for removably receiving a source of light in order to facilitate curing the photocurable adhesive material. | 2008-09-25 |
20080233531 | METHODS AND ASSEMBLIES FOR MAKING AN ORTHODONTIC BONDING TRAY USING RAPID PROTOTYPING - Indirect bonding trays for orthodontic treatment are made from a model of the patient's dental arch that is manufactured using digital data and rapid prototyping processes. The model includes one or more guides for orienting an orthodontic appliance in a desired position on a model tooth of the dental arch model. A holder is connected to the archwire slot of the appliance and is brought into contact with the guide in order to move the appliance to its intended position for subsequent manufacture of the indirect bonding tray. | 2008-09-25 |
20080233532 | TOOTH SHADE ANALYZER SYSTEM AND METHODS - The invention relates to a method of determining a tooth shade of at least a portion of a patient's tooth which is to be replaced or restored, by capturing an electronic image of the patient's tooth, the image including color information representative of the patient's tooth shade; storing color information representative of known tooth shades with each known tooth shade representing a different tooth color; calibrating the color information of the patient's tooth and the color information representative of known tooth shades; and comparing the color information of the patient's tooth with the stored color information to identify a single tooth shade or a combination of tooth shades with a color or combined color corresponding to the color of at least a portion of the patient's tooth, such that the patient's tooth may be comprised of a single tooth shade or a plurality of tooth shades. | 2008-09-25 |
20080233533 | Light curing device - The invention relates to a light curing device, comprising a light source which is accommodated in a housing which has a light exit, through which light leaves the housing. It is provided that the light exiting direction of the light beam is variable, in particular infinitely variable. | 2008-09-25 |
20080233534 | Light curing device/base station combination - The invention relates to a light curing device/base station combination, comprising a heat absorbing element, which is in particular metallic, and which is in thermally conducting connection with a heat source, in particular a light source, and in particular comprising a handle. The base station ( | 2008-09-25 |
20080233535 | Dental implement and method for inhibiting bleeding during a root canal procedure - A dental implement for applying a hemostatic compound to a root canal of a person's tooth includes an elongate applicator having an upper section and a lower section. The lower section includes a tip having a generally pointed configuration. The tip and lower section may be coated with a hemostatic agent that inhibits bleeding. A user may hold the applicator by its upper section and insert the lower section and tip into a root canal for applying the hemostatic compound to the tissues therein, whereby to inhibit bleeding during a root canal procedure. | 2008-09-25 |
20080233536 | Dental machining device and method for monitoring sealing elements in dental machining devices - The invention relates to dental machining device ( | 2008-09-25 |
20080233537 | Healing components for use in taking impressions and methods for making the same - The present invention provides a healing abutment for attachment to a dental implant with marking locations thereon. The marking locations either lack or have markers that provide a binary code system for retrieving unique information about the healing abutment and the underlying implant. | 2008-09-25 |
20080233538 | TWO-PART SCREW FOR A DENTAL IMPLANT - A two-part screw for a dental implant with a screw rod and a nut, which is sized so as to be received into a screw passage channel of an abutment in an axially secured manner, and which is formed with an inner thread for screwing connection to a first coronal thread on the screw rod, the screw rod being furnished with a second apical thread, which is formed to screwingly connect the screw to the dental implant; the construction made up of screw rod and nut can be replaced with a screw with a screw bush. | 2008-09-25 |
20080233539 | Abutment For a Tooth Implant - The abutment for a tooth implant comprises a connecting portion for fixing to the tooth implant and a post with a groove. In one example, the connecting portion and the post are made in one-piece and the abutment has the form of a sleeve. Such an abutment permits repeated further treatment and use of snap-on elements, in particular, the use of a snap-on cap which can be used as a manipulation element or as a base for the production of a crown. | 2008-09-25 |
20080233540 | POWDER BLAST TOOL, POWDER RESERVOIR, INSERT FOR POWDER RESERVOIR AND METHOD OF DENTAL TREATMENT - A powder blast tool for mixing a powder with a pressurised gas, having at least one powder reservoir, with supply lines for the pressurised gas, and a discharge line, which is connected to a discharge nozzle, at which a powder-gas mixture and optionally pressurised water are discharged, wherein the powder blast tool can preferably be connected to plural powder reservoirs simultaneously and exchangeably, wherein at least one receiving region with at least one mixture terminal and at least one gas terminal is disposed on the powder blast tool and wherein the powder reservoir has a coupling region for exchangeable connection of the powder reservoir to the powder blast tool. Also disclosed are a suitable powder reservoir and an insert for such powder reservoirs and a corresponding method of dental treatment. | 2008-09-25 |
20080233541 | Method and Device for Enhancing the Treatment of Teeth and Gums - An autonomous device which includes a trough, shaped for the immersion of teeth and/or gums of a dental arch, or a dental brace and one or more electrical components which provide functionality is disclosed. The device is useful in methods for whitening teeth, relieving pain, treating bacteria, treating bad breath, and healing. Inserts for use with the device are also disclosed. | 2008-09-25 |
20080233542 | System for optimising the formation of refractory moulds for multiple metal castings in the production of fixed dental prostheses - According to the invention, the components of the system have been optimised such that they interact and complement each other and such that one cannot operate without the other in the formation of refractory moulds for multiple metal castings in the production of fixed dental prostheses. The invention also relates to a mechanical metal device for positioning increased length refractory cylinders in standard horizontal centrifuges, thereby increasing the number of fixed dental prostheses that can be cast at one time. | 2008-09-25 |
20080233543 | Video Capture, Recording and Scoring in Firearms and Surveillance - A video camera and recording device integrated with a real or toy weapon to provide video recording of the assault and aiming process of the weapon holder in operational training, actual combat, hunting, sports and gaming scenarios. A video camera is boresighted with the weapon, and a video memory stores the recorded dynamic scenario, and a trigger sensor which continually senses and records the triggering actions imposed by the weapon holder. The trigger sensor is attached to the actual trigger of the weapon thus enabling normal operation of the weapon. The video camera, may be mounted internally within the bore of the weapon, such that the external form of the weapon is not altered, thus achieving closer operation to real life situations. The recorded trigger data is utilized upon playback of the recorded video, enabling quick review and scoring of the recorded aiming process for training and gaming. | 2008-09-25 |
20080233544 | Collapsible flight training hood - A flight training hood that can be collapsed for compact storage. A spring member can quickly restore the flight training hood to its pre-collapsed position ready for use. | 2008-09-25 |
20080233545 | SYSTEM AND METHOD FOR SIMULTANEOUSLY ADVERTISING CONSUMER PRODUCTS AND SERVICES AND EDUCATING STUDENTS - A system and method for simultaneously advertising and educating students which uses a corporate sponsor of consumer products or service which pays for a modular hands-on real-life simulation of an occasion for encountering the products or service and provides ability to learn and to permit revenue sharing via an internet teaching and testing component. | 2008-09-25 |
20080233546 | Visual scene displays, uses thereof, and corresponding apparatuses - A method and a device are provided. In at least one embodiment, the method includes receiving an indication of selection of a key from a keyboard, including at least one of a polysemous symbol and a compilation symbol; and displaying a scene related to the selected at least one of a polysemous symbol and a compilation symbol. In at least one embodiment, the device includes a keyboard including a plurality of keys including polysemous symbols; and a display to display, on at least a portion thereof and in response to receiving an indication of selection of a key including at least one of a polysemous symbol and a compilation symbol, a scene related to the selected at least one of a polysemous symbol and a compilation symbol. | 2008-09-25 |
20080233547 | Reading motivational system - A method of promoting literacy through encouraging reading includes the step of providing a medium capable of storing and displaying information. Information relating to an individual is entered onto the medium, with at least a portion of the information being related to current reading materials of the individual. The medium is placed into a display mechanism adapted and constructed to be worn on the person of the individual, and the display mechanism is then worn by the individual. | 2008-09-25 |
20080233548 | Method Of and Light System For Dance Instruction - A method of using lights and a light system for teaching dance, particularly to students with hearing impairments. The method or dance instruction includes a light bar having a plurality of first lights and second lights. The first and second lights are visually distinguishable. The first lights are turned on and off to display a pre-selected time signature pattern, and the second lights of the light bar are turned on and off to display a pre-selected and count time signature pattern. A light system for dance instruction includes a light bar having a first lights and second lights, which are visually distinguishable, and a control unit for: a) turning the first lights of the light bar on and off to display a pre-selected time signature pattern; and b) turning the second lights of the light bar on and off to display a pre-selected and count time signature pattern. | 2008-09-25 |
20080233549 | BODY ANATOMIE VISUAL AID GARMENTS - One embodiment of the apparatus includes clothing depicting a selected body anatomy so that when the clothing is associated with the body to be massaged the clothing presents the location of the body system of interest. Such clothing preferably forms a visual aid that is associated with a body to be massaged that shows (a) the location of a muscle system (with or without labels) perhaps including a split view overlaying muscles and underlying muscles, (b) a skeletal system depicting bony landmarks and origin, insertion and function of attached muscles, (c) a lymphatic system showing circulation paths, (d) the nine regions and quadrants of a human body, and (e) the location of organs and acupressure points including chakras. Such a visual aid would preferably be useful for allowing a student to better comprehend the meaning of terms such as medial, lateral, prone, and supine and the locations of body “landmarks.” | 2008-09-25 |
20080233550 | Method and apparatus for technology-enhanced science education - The interactive science learning method consists of a sequence of hands-on experiments with matching computer simulations that connect a student's prior experience to core science concepts, and the apparatus implements the learning method. A tutorial is employed to evoke a student's prior experience, and equates that experience with a hands-on laboratory experiment performed by the student. Computer generated simulations emulate the hands-on experiment to reinforce the concept, by picturing the phenomenon more completely and by allowing the student to instantaneously see how changing input variables affects an outcome, and may also extrapolate the concept to different physical scales. A remote sensor device, such as may for example incorporate an accelerometer feature, can be employed to transmit, in real time, signals containing information that is representative of phenomena that are sensed or experienced by the student, for use in the computer-generated simulations. | 2008-09-25 |
20080233551 | WIRELESS LEARNING SYSTEM - In one embodiment, the present invention provides a wireless learning system that includes a master control unit and a plurality of trigger units. Each trigger unit is able to wirelessly communicate with the master control unit and the other trigger units. Each trigger unit further includes at least one trigger switch and can provide an indication when that trigger unit is the first one of the trigger units to have its trigger switch actuated. | 2008-09-25 |
20080233552 | METHOD OF CROSS-LINKING AMNION TO BE AN IMPROVED BIOMEDICAL MATERIAL - The present invention discloses a method of cross-linking amnion to be an improved biomedical material. The present invention adopts the amnion cross-linked by EDC (N-(3-dimethylaminopropyl)-N′-ethyl-carbodiimide HCI) or NHS (N-hydroxysuccinimide), and the cross-linked amnion not only has more resistance to protease, but also binds specific extracellular matrix (ECM) such as heparin by using cross-linked functional group. Further, by using the affinity of the ECM with specific growth factors, the amnion can be an efficient carrier for specific growth factor. Hence, some specific diseases may be treated. | 2008-09-25 |
20080233553 | Method and Apparatus for Separating and Harvesting Cells From a Whole Blood Sample - An automated method and apparatus for separating and harvesting cells of interest, e.g., mononuclear cells, in a whole blood sample. The method of the invention uses the aspirating/dispensing probe of an automated sample preparation instrument to underlay a density gradient medium beneath a whole blood sample in a centrifugation tube, and the same probe is used to harvest cells of interest from a cell layer formed in the tube as a result of a centrifugation step. In harvesting cells, the probe is advanced inside the tube by a fixed, predetermined distance at which the probe tip (i.e., its aspiration port) is known to be located at, or within a predetermined distance below, the bottom of the cell layer. A predetermined volume of liquid is then aspirated through the probe tip, whereby most cells of interest (and more than 90% of those cells that can be harvested by a flawless manual method) are removed from the cell layer and collected for analysis. Preferably, the probe is caused to move laterally with respect to the tube during the aspiration of the cell layer, whereby cells offset from the center of the container are readily harvested. | 2008-09-25 |
20080233554 | COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING THE SAME - The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the present invention relates to the use of a preservative composition having an antiplatelet agent, an anticoagulant, and an oxygen carrier, for maintaining the freshness of platelets. Additionally, the composition may also contain an ultra-short acting broad spectrum anti-microbial agents. The preservative composition may be used to store platelets in a liquid state, a frozen state, or a freeze-dried state. | 2008-09-25 |
20080233555 | HOMOGENEOUS ASSAY FOR ENZYMATIC ACTIVITY - An assay is disclosed for measuring activity of enzymes, such as kinases, phosphatases, and proteses. Measurements of enzymatic activity are accomplished in a homogenous assay format utilizing a fluorescence quenching technique employing paramagnetic metal ions. | 2008-09-25 |
20080233556 | CYTOTONIC PROTEIN AND UTLIZATION THEREOF - This invention relates to a new cytotoxic protein (M toxin, mucous layer devastating toxin) produced by | 2008-09-25 |
20080233557 | PNA Probes, Kits, and Methods for Detecting Lamivudine-Resistant Hepatitis B Viruses - Disclosed are peptide nucleic acid (PNA) probes to detect lamivudine resistant mutants of hepatitis B virus (HBV), which causes acute and chronic hepatitis, kits for detecting lamivudine resistant HBV comprising the PNA probes, and methods for detecting lamivudine resistant HBV by using the kits. They can accurately detect mutations of rtL180M, rtM204V, rtM204I and rtV2071 within B and C domains of HBV DNA polymerase gene, the main cause of lamivudine resistance, as well as mixed mutants of more than one mutant. They can detect lamivudine resistant HBV with high specificity and sensitivity. | 2008-09-25 |
20080233558 | Inhibitors of viral entry screening method - In one aspect the invention relates to a method for identifying inhibitors or viral entry comprising providing an indicator cell wherein said cell expresses a reporter gene and wherein said cell is capable of supporting entry by an effector particle, providing a candidate inhibitor of viral entry, co-compartmentalizing said candidate inhibitor and said indicator cell, contacting said indicator cell with an effector particle, incubating to allow any effector particle entry to take place, and assaying said indicator cell for reporter gene activity, wherein detection of reporter gene activity identifies the candidate inhibitor as an inhibitor for viral entry. Preferably the effector particle is HIV, preferably the reporter gene is a CD | 2008-09-25 |
20080233559 | Inhibition of HIV-1 Replication by Disruption of the Processing of the Viral Capsid-Spacer Peptide 1 Protein - Inhibition of HIV-1 replication by disrupting the processing of the viral Gag capsid (CA) protein (p24) from the CA-spacer peptide 1 (SP1) protein precursor (p25) is disclosed. Amino acid sequences containing a mutation in the Gag p25 protein, with the mutation resulting in a decrease in the inhibition of processing of p25 to p24 by dimethylsuccinyl betulinic acid or dimethylsuccinyl betulin, polynucleotides encoding such mutated sequences and antibodies that selectively bind such mutated sequences are also included. Methods of inhibiting, inhibitory compounds and methods of discovering inhibitory compounds that target proteolytic processing of the HIV Gag protein are included. In one embodiment, such compounds inhibit the interaction of the HIV protease enzyme with Gag by binding to Gag rather than to the protease enzyme. In another embodiment, viruses or recombinant proteins that contain mutations in the region of the Gag proteolytic cleavage site can be used in screening assays to identify compounds that target proteolytic processing. | 2008-09-25 |
20080233560 | DNA-transfection system for the generation of infectious influenza virus - The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus. Attenuated or inactivated RNA viruses produced by the present invention may be administered to a patient in need of vaccination by any of several routes including intranasally or intramuscularly. | 2008-09-25 |
20080233561 | Method for Measuring Cytopathic Effect Due to Viral Infection in Cells Using Electric Cell-Substrate Impedance Sensing - A method of measuring cytopathic effect in cells includes providing cells in culture, using electric cell-substrate impedance sensing (ECIS) to measure the resistance of current associated with the cells, and quantifying the cytopathic effect (CPE) associated with the cells based on the measured resistance. The cells may be identified as being infected with a virus if the CPE associated with the cells is above a predetermined level. Alternatively, the cells may be provided in a healthy monolayer and infected with a virus in order to measure the effect of the virus on CPE associated with the cells. Cells may also be treated with candidate antiviral agents and the effects of the agents on the virus-infected cells may be measured to screen for and identify actual antiviral agents. | 2008-09-25 |
20080233562 | Method of Estimating Antitumor Effect of Histone Deacetylase Inhibitor - The present invention provides a method of obtaining a gene capable of becoming an index for predicting the efficacy of a histone deacetylase inhibitor, which comprises at least (I) a step of dividing tumor cells into a histone deacetylase inhibitor sensitive tumor cell and a histone deacetylase inhibitor resistant tumor cell, and (II) a step of examining the gene expression pattern of each of the sensitive tumor cell and the resistant tumor cell, and a step of selecting (i) a gene showing high expression in the sensitive tumor cell and low expression in the resistant tumor cell, or (ii) a gene showing low expression in the sensitive tumor cell and high expression in the resistant tumor cell, in order to provide a gene useful for predicting the efficacy, particularly an antitumor effect, of a histone deacetylase inhibitor, for a tumor desired to be treated. | 2008-09-25 |
20080233563 | Enhanced Detection of Rna Using a Panel of Truncated Gene-Specific Primers for Reverse Transcription - The present invention provides truncated gene-specific primers in panels that can be used during the reverse transcription step of RT-PCR to increase signal detection of cancer gene markers in a tissue sample. Also provided are forward and reverse primers for RT-PCR. Methods of using the primers are also provided. | 2008-09-25 |
20080233564 | Methods of Using Databases to Greate Gene-Expression Microarrays, Microarrays Greated Thereby, and Uses of the Microarrays - Methods of preparing biological databases, and databases prepared according to those methods. In some embodiments, the methods can be performed entirely using computer resources, relying solely on publicly available biological sequence information. The methods of the invention can be used to generate species-specific nucleic acid microarrays | 2008-09-25 |
20080233565 | PKHDL1, a homolog of the autosomal recessive kidney disease gene - Nucleic acids encoding fibrocystin-L polypeptides and fibrocystin-L polypeptides are provided. Antibodies against the polypeptides, vectors and host cells containing the nucleic acids, methods for using the nucleic acids and polypeptides, and compositions and articles of manufacture also are provided. | 2008-09-25 |
20080233566 | Methods and materials for detecting mutations in quasispecies having length polymorphisms - The present invention is directed to a method for detecting the presence or absence of a mutation of interest in the nucleic acid of a pathogen, wherein the mutation of interest is located adjacent to a length polymorphism defining multiple quasispecies of the pathogen. | 2008-09-25 |
20080233567 | Companion diagnostic assays for cancer therapy - A method for classifying cancer patients as eligible to receive cancer therapy with a small molecule inhibitor of Bcl-2 comprising determination of the presence or absence in a patient tissue sample of chromosomal copy number status at the chromosomal locus 13q14 comprising the microRNA's miR15 | 2008-09-25 |
20080233568 | Detection of Extracellular Tumor-Associated Nucleic Acid in Blood Plasma or Serum Using Nucleic Acid Amplification Assays - This invention relates to detection of specific extracellular nucleic acid in plasma or serum fractions of human or animal blood associated with neoplastic or proliferative disease. Specifically, the invention relates to detection of nucleic acid derived from mutant oncogenes or other tumor-associated DNA, and to those methods of detecting and monitoring extracellular mutant oncogenes or tumor-associated DNA found in the plasma or serum fraction of blood by using rapid DNA extraction followed by nucleic acid amplification with or without enrichment for mutant DNA. In particular, the invention relates to the detection, identification, or monitoring of the existence, progression or clinical status of benign, premalignant, or malignant neoplasms in humans or other animals that contain a mutation that is associated with the neoplasm through detection of the mutated nucleic acid of the neoplasm in plasma or serum fractions. The invention permits the detection of extracellular, tumor-associated nucleic acid in the serum or plasma of humans or other animals recognized as having a neoplastic or proliferative disease or in individuals without any prior history or diagnosis of neoplastic or proliferative disease. The invention provides the ability to detect extracellular nucleic acid derived from genetic sequences known to be associated with neoplasia, such as oncogenes, as well as genetic sequences previously unrecognized as being associated with neoplastic or proliferative disease. The invention thereby provides methods for early identification of colorectal, pancreatic, lung, breast, bladder, ovarian, lymphoma and all other malignancies carrying tumor-related mutations of DNA and methods for monitoring cancer and other neoplastic disorders in humans and other animals. | 2008-09-25 |
20080233569 | Detection of Extracellular Tumor-Associated Nucleic Acid in Blood Plasma or Serum Using Nucleic Acid Amplification Assays - This invention relates to detection of specific extracellular nucleic acid in plasma or serum fractions of human or animal blood associated with neoplastic or proliferative disease. Specifically, the invention relates to detection of nucleic acid derived from mutant oncogenes or other tumor-associated DNA, and to those methods of detecting and monitoring extracellular mutant oncogenes or tumor-associated DNA found in the plasma or serum fraction of blood by using rapid DNA extraction followed by nucleic acid amplification with or without enrichment for mutant DNA. In particular, the invention relates to the detection, identification, or monitoring of the existence, progression or clinical status of benign, premalignant, or malignant neoplasms in humans or other animals that contain a mutation that is associated with the neoplasm through detection of the mutated nucleic acid of the neoplasm in plasma or serum fractions. The invention permits the detection of extracellular, tumor-associated nucleic acid in the serum or plasma of humans or other animals recognized as having a neoplastic or proliferative disease or in individuals without any prior history or diagnosis of neoplastic or proliferative disease. The invention provides the ability to detect extracellular nucleic acid derived from genetic sequences known to be associated with neoplasia, such as oncogenes, as well as genetic sequences previously unrecognized as being associated with neoplastic or proliferative disease. The invention thereby provides methods for early identification of colorectal, pancreatic, lung, breast, bladder, ovarian, lymphoma and all other malignancies carrying tumor-related mutations of DNA and methods for monitoring cancer and other neoplastic disorders in humans and other animals. | 2008-09-25 |
20080233570 | METHODS FOR IDENTIFICATION OF SEPSIS-CAUSING BACTERIA - The present invention provides compositions, kits and methods for rapid identification and quantification of sepsis-causing bacteria by molecular mass and base composition analysis. | 2008-09-25 |
20080233571 | Method for identifying compounds which affect synaptogenesis - A method is provided for identifying a compound which affects the formation of AMPA receptors into aggregates. A method is also provided for identifying a compound which affects the formation of synaptic connections. A method is provided for identifying a compound that modulates immediate early gene expression. A method is further provided for increasing the number of excretory synapses of a neuron, including introducing into the neuron a polynucleotide sequence encoding a Narp operatively linked to a promoter, or a Narp polypeptide, thereby increasing the number of excretory synapses of the neuron. A method is provided for treating a subject with a disorder associated with a decrease in a function or expression of Narp, including administering to the subject a therapeutically effective amount of a compound that augments Narp function or expression. A method is provided for treating a subject with a disorder associated with an increase in a function or expression of Narp, including administering to the subject a therapeutically effective of a compound that inhibits Narp function or expression. A method is provided for treating a patient having or at risk of having a disorder associated with decreased Narp expression. The method includes introducing into a cell of a patient having a disorder associated with decreased Narp expression or function a polynucleotide sequence encoding a Narp polypeptide operatively linked to a promoter. A method is provided for treating a subject having a deficiency in a neuron's immediate early gene responsiveness to a stimulus. The method includes administering a nucleic acid encoding a Narp polypeptide to said subject, wherein the administration results in amelioration of the deficiency. | 2008-09-25 |
20080233572 | METHODS AND COMPOSITIONS FOR THE DETECTION AND QUANTIFICATION OF E.COLI AND ENTEROCOCCUS - The present invention is drawn to methods and compositions for the rapid assessment of fecal indicator bacteria in a sample. Provided herein are novel primer and probe compositions for use in detecting the presence of these organisms in a sample, particularly using quantitative PCR methods. Provided herein are novel oligonucleotide primers and probes, including the primers set forth in SEQ ID NO:1-4, the novel oligonucleotide probe sequences set forth in SEQ ID NO:5-8, and methods for using these primers and probes for the detection and/or quantification of fecal indicator bacteria, particularly | 2008-09-25 |
20080233573 | Gene expression profiling for identification, monitoring and treatment of transplant rejection - The present invention provides methods of characterizing organ transplant rejection or inflammatory conditions associated with organ transplant rejection using gene expression profiling. | 2008-09-25 |
20080233574 | Map-Based Genome Mining Method for Identifying Regulatory Loci Controlling the Level of Gene Transcripts and Products - The invention pertains to a method for identifying one or more regions within a genome of an organism of interest that mediate the expression of one or more genes of interest. The method comprises identifying a first and a second organism of interest, the first organism of interest is characterized by exhibiting a measurable response to an environmental stimulus, or otherwise, exhibiting a phenotype associated with differential gene expression associated with a process of interest. The second organism of interest is characterized by lacking or not exhibit as strong a response to the stimulus as that observed within the first organism of interest, or it exhibits a different phenotype compared with that of the first organism of interest, wherein the different phenotype is associated with the process of interest, or it exhibits a phenotype of interest that segregates when compared with the first organism of interest, or a combination thereof. The first and second organisms of interest are crossed to produce a population of segregated progeny and RNA is extracted from each of the segregated progeny. The level of gene expression for one or more genes of interest that are associated with the response to an environmental stimulus, or process of interest is quantified. A linkage map of the segregated progeny using one or more markers is prepared, and the relationship between said one or more markers on the linkage map and the gene expression of the one or more genes of interest is determined and one or more quantitative trait loci (QTL) identified. This method also pertains to identifying one or more QTLs associated with one or more genes of interest in segregated progeny that are subjected a desired environmental stimulus. Furthermore, this method may be used for the identification of one or more QTL corresponding to a transcription factor or any factor controlling the expression of one or more genes of interest, and the one or more genes located at the one or more QTL may be isolated and characterized. | 2008-09-25 |
20080233575 | Methods for increasing accuracy of nucleic scid sequencing - The invention provides methods for improving the fidelity of a sequencing-by-synthesis reaction by resequencing at least a portion of a nucleic acid template. | 2008-09-25 |
20080233576 | METHOD FOR FEATURE SELECTION IN A SUPPORT VECTOR MACHINE USING FEATURE RANKING - In a pre-processing step prior to training a learning machine, pre-processing includes reducing the quantity of features to be processed using feature selection methods selected from the group consisting of recursive feature elimination (RFE), minimizing the number of non-zero parameters of the system (l | 2008-09-25 |
20080233577 | METHOD FOR PRODUCING LIGANDS, LIGANDS AND TEST KIT - The invention relates to a method for producing ligands, in particular aptamers. With this method, a target substance is offered to a set of candidate ligands, and the unbonded ligands are separated out by a cross-flow filtration process. The retentate, which contains ligand-target substance complexes, then undergoes further continuous cross-flow filtration while chemical and/or physical parameters are being varied. After each variation of a parameter, those candidate ligands whose bond with the target substance was dissolved by the parameter variation are collected in separate fractions and separately multiplied. | 2008-09-25 |