40th week of 2016 patent applcation highlights part 11 |
Patent application number | Title | Published |
20160287717 | Core and Surface Modification of Mesoporous Silica Nanoparticles to Achieve Cell Specific Targeting In Vivo. - In one aspect, the invention provides mesoporous silica nanoparticles (MSNPs), monodisperse populations of MSNPs and related protocells which exhibit single cell binding specificity to the substantial exclusion of non-targeted cells. For example, MSNPs and protocells of the invention may be used to target specific delivery of therapeutic agents to cancer cells or to specific blood vessel types (e.g. in the arterial, venous and/or capillary vessels or any combination of vessels). Related protocells, pharmaceutical compositions and therapeutic and diagnostic methods are also provided. | 2016-10-06 |
20160287718 | NOVEL POLYMER CONJUGATE - The present invention concerns a conjugate of a domain I β2GP1 polypeptide with a water-soluble polymer, wherein the polymer is bound via two cysteine residues derived from a disulfide bridge in the domain I β2GP1 polypeptide. | 2016-10-06 |
20160287719 | SUSTAINED DRUG DELIVERY SYSTEM - A drug composition comprising a charged moiety coupled to a therapeutic compound is disclosed. The charged moiety is configured to interact with at least one type of component of opposite charge in a biological tissue to create an in situ depot for prolonged drug delivery. The biological tissue may be eye tissue or any tissue containing charged components. | 2016-10-06 |
20160287720 | NOVEL SEZ6 MODULATORS AND METHODS OF USE - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | 2016-10-06 |
20160287721 | PYRROLOBENZODIAZEPINES AND TARGETED CONJUGATES - This invention relates to pyrrolobenzodiazepines (PBDs), in particular pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position in each monomer unit, and their inclusion in targeted conjugates. The differing substituent groups may offer advantages in the preparation and use of the compounds, particularly in their biological properties and the synthesis of conjugates, and the biological properties of these conjugates. | 2016-10-06 |
20160287722 | Immunoconjugates with an Intracellularly-Cleavable Linkage - The invention relates to therapeutic conjugates with improved ability to target various cancer cells containing a targeting moiety and a therapeutic moiety. The targeting and therapeutic moieties are linked via an acid cleavable linkage that increases therapeutic efficacy of the immunoconjugate. | 2016-10-06 |
20160287723 | Method of Fabricating Anticancer Drug Having Doxorubicin Bonded with Gold Nanoparticles - Albumin and doxorubicin are bonded through reaction. The bonded albumin and doxorubicin are added with a gold-nanoparticles solution for reaction. After being purified with water in a column, the liquid phase of gold-nanoparticles is changed into a phosphate buffer for obtaining an anticancer drug having doxorubicin bonded with gold nanoparticles. Thus, with the high biocompatibility and the big surface areas, gold nanoparticles are used in biological applications and used as carriers for increasing drug accumulation on tumor. The bonding between gold nanoparticles and doxorubicin increases stability of doxorubicin. Besides, doxorubicin has tumor-killing effect for cancer therapy. | 2016-10-06 |
20160287724 | COMPOSITIONS AND METHODS FOR CARDIAC REGENERATION - The invention relates to the use of a CITED4 polypeptide and/or a microRNA-222 or precursor (e.g., pre-miR-222) or mimic thereof, for treating a cardiovascular disease or pathological condition, such as heart failure, myocardial infarction, and for promoting post-myocardial infarction cardiac remodeling in heart tissue. | 2016-10-06 |
20160287725 | LIVER SPECIFIC DELIVERY OF MESSENGER RNA - Disclosed herein are compositions and methods of modulating the expression of gene or the production of a protein by transfecting target cells with nucleic acids. The compositions disclosed herein demonstrate a high transfection efficacy and are capable of ameliorating diseases associated with protein or enzyme deficiencies. | 2016-10-06 |
20160287726 | CATIONIC CONTRAST AGENTS AND METHODS OF USING THE SAME - Gadolinium complexes for use as contrast agents, and methods for making and using the gadolinium complexes, are described. The contrast agent complexes preferably have a net positive charge, and can electrostatically interact with glycosaminoglycans to improve the delineation of fine tears within cartilage, detection of cartilage degeneration, or assessment of cartilage thickness, morphology, or glycosaminoglycan content via magnetic resonance imaging. | 2016-10-06 |
20160287727 | PHOTOACOUSTIC IMAGING CONTRAST AGENT - A photoacoustic imaging contrast agent comprising a biodegradable polymer backbone grafted with a photoacoustic contrast agent is provided. A method of preparing a photoacoustic imaging contrast agent, and a method of imaging living tissue are also provided. | 2016-10-06 |
20160287728 | NON-INVASIVE DIAGNOSTIC AGENTS AND METHODS OF DIAGNOSING INFECTIOUS DISEASE - The present invention is directed to novel non-invasive diagnostic tools to diagnose numerous infectious disease states or conditions. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these disease states. The novel imaging probe is capable of detecting infected cells, as well tissue. This represents a quantum step forward in the diagnosis and staging of NHL using non-invasively molecular imaging techniques. This novel probe will also be useful to monitor patients response to therapeutic treatments and other interventions or therapies used in the treatment of these disease states or conditions. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states. Pharmaceutical compositions are also described. | 2016-10-06 |
20160287729 | SMALL MOLECULE IMAGING OF FUNGI BY POSITRON EMISSION TOMOGRAPHY SCANNING - Disclosed herein are isotopically labeled calcofluor derivatives and uses of such to detect fungi, such as filamentous fungi, including | 2016-10-06 |
20160287730 | LABELED EVANS BLUE DYE DERIVATIVE FOR IN VIVO SERUM ALBUMIN LABELING - Disclosed is a compound of formula (I): | 2016-10-06 |
20160287731 | Compounds for Positron Emission Tomography - Described herein are compounds, compositions, and methods for diagnosing and/or monitoring pathogenic disease using positron emission tomography. Also described are conjugates of the formula B-L-P, wherein B is a radical of a targeting agent selected from vitamin receptor binding ligands (such as folate), PSMA binding ligands, or PSMA inhibitors; L is a divalent linker comprising aspartic acid, lysine, or arginine, and P is a radical of an imaging agent or radiotherapy agent, such as a radionuclide or radionuclide containing group, or a radical of a compound capable of binding a radionuclide, such as a metal chelating group. | 2016-10-06 |
20160287732 | TUMOR THERAPY BY BISPECIFIC ANTIBODY PRETARGETING - The present invention relates to methods and compositions for pretargeting delivery of alpha-emitting radionuclides, such as | 2016-10-06 |
20160287733 | PICOLINATE CROSS-BRIDGED CYCLAMS, CHELATES WITH METALLIC CATIONS AND USE THEREOF - Chelates resulting from the complexation of picolinate cross-bridged cyclams of formula (I), wherein n and the substituents L1-L4 and R1-R5 are as defined, with metallic cations. Picolinate cross-bridged cyclam ligands of formula (I), the use of chelates in nuclear medicine and the use of ligands in cations detection or epuration of effluents are also described. | 2016-10-06 |
20160287734 | 18F LABELING OF PROTEINS USING SORTASES - The present invention, in some aspects, provides methods, reagents, compositions, and kits for the radiolabeling of proteins, for example, of proteins useful for positron emission tomography (PET) or single-photon emission computed tomography (SPECT) (e.g., for diagnostic and therapeutic applications), using sortase-mediated transpeptidation reactions. Some aspects of this invention provide methods for the conjugation of an agent, for example, a radioactive agent or molecule to diagnostic or therapeutic peptides or proteins. Compositions comprising sortagged, radiolabeled proteins as well as reagents for generating radiolalebed proteins are also provided. Kits comprising reagents useful for the generation of radiolabeled proteins are provided, as are precursor proteins that comprise a sortase recognition motif. | 2016-10-06 |
20160287735 | PLASMA INSTALLATION WITH A SEPARATELY TRANSPORTABLE VESSEL - A plasma installation includes at least two separate components being a vessel for an object to be processed and a plasma unit having an electrical plasma source for igniting a plasma in the vessel. The plasma unit has no additional subassembly for other media so that the plasma unit can be constructed in a structurally particularly simple manner and readily operated. In a particularly preferred manner, the vessel comprises a vessel body of glass. The vessel body is preferably constructed in one piece and surrounds the object completely. The plasma can be ignited spaced apart from the plasma unit by means of a high-frequency generator, an induction coil and/or a magnetron of the electrical plasma source. | 2016-10-06 |
20160287736 | Static Fluid Disinfecting Systems and Related Methods - Static fluid disinfecting system and related methods. Implementations of a method of disinfecting a fluid include statically contacting a fluid included in in a container with an open-celled foam where the open-celled foam is coated with a quaternary organosilane coating produced from a quaternary ammonium organosilane reagent where the fluid contains one or more microorganisms. | 2016-10-06 |
20160287737 | Purified Hydrogen Peroxide Gas Microbial Control Methods and Devices - The present invention relates to methods and devices for providing microbial control and/or disinfection/remediation of an environment. The methods generally comprise: generating a Purified Hydrogen Peroxide Gas (PHPG) that is substantially free of, e.g., hydration, ozone, plasma species, and/or organic species; and directing the gas comprising primarily PHPG into the environment such that the PHPG acts to provide microbial control and/or disinfection/remediation in the environment, preferably both on surfaces and in the air. | 2016-10-06 |
20160287738 | Aromatherapy apparatus and housing - The present invention is an apparatus for employing aromatherapy and binaural sounds for inducing a state of relaxation in a user who may be anxious, upset, or experiencing sleeping difficulties. The apparatus comprises a shape memory foam pillow, a pair of stereo speakers, an aromatherapy diffuser, a pillowcase comprised of heat-transfer fabric, an optional vibrating device, a canopy and a housing to support these elements. The user connects a smartphone or digital audio device to the speakers, activates the aromatherapy diffuser and the vibrating device, and lays his or her head down on the pillow beneath the canopy. Ideally, the smartphone or music device should have a meditation or binaural sound application, which would be tuned to a specific beat frequency, such as 10 Hertz. The combined action of essential oil vapors and binaural sounds should enable the user to relax or sleep more soundly. | 2016-10-06 |
20160287739 | AIR FRESHENER CANISTERS - An air freshener canister includes a container, a nipple thereon and a cap threadably matable therewith. The cap can be positioned along the length of the nipple from a closed position with the cap rim against the exterior surface of the container and an open position wherein there is spacing between the rim and exterior surface. A volatile liquid in the container emits air freshener vapors. A wick runs from the liquid to the nipple. When the cap is in the open position, vapors escape from the wick through the spacing. When the cap is in the closed position the vapors are prevented from escaping. When the cap is removed from the nipple the container may be refilled with the volatile liquid. The escape of vapors may be increased or decreased by positioning the cap on the nipple to increase or decrease the spacing. | 2016-10-06 |
20160287740 | SUSPENSIONS AND MATERIALS COMPRISING COMPLEXES OF CHITIN NANOFIBRILS WITH METALS - The present invention refers to an aqueous suspension comprising chitin nanofibrils in a complex with at least one metal selected from the group Ag, Cu and Bi and at least one thickener, as well as to a process for the preparation thereof. Moreover, the present invention provides a process for the manufacturing of biomedical materials from said suspension, and biomedical articles based on said materials. | 2016-10-06 |
20160287741 | METASTABLE SILVER NANOPARTICLE COMPOSITES WITH COLOR INDICATING PROPERTIES - Embodiments of the present invention relate to a metastable silver nanoparticle composite, a process for its manufacture, and its use as a source for silver ions and/or colorimetric signaling In various embodiments, the composite comprises, consists essentially of or consists of metastable silver nanoparticles that change shape when exposed to moisture, a stability modulant that controls the rate of the shape change, and a substrate to support the silver nanoparticles and the modulant. | 2016-10-06 |
20160287742 | HOT MELT WETNESS INDICATOR COMPOSITION THAT INCLUDES A LEUCO DYE, AND ARTICLES INCLUDING THE SAME - A hot melt wetness indicator composition that includes a water insoluble thermoplastic polymer, an anionic surfactant, a leuco dye, and a component selected from the group consisting of acid, rosin-based tackifying agent, plasticizer and combinations thereof, and is homogeneous is disclosed. The hot melt wetness indicator composition exhibits a color change after contact with water. | 2016-10-06 |
20160287743 | MULTILAYER COMPOSITION - Disclosed herein is a multilayer composition comprising: a first layer comprising a first material which is at least partially impregnated with a second material wherein the first material is a gel material and the second material is a flexible porous material, and a second layer comprising a low friction material wherein the composition is adapted so that the first layer is in fluid flow communication with a wound or skin of a wearer in use. | 2016-10-06 |
20160287744 | VASCULAR EMBOLIC SYSTEM - Systems and methods of blocking a biological vessel are provided. The systems and methods may comprise introducing to the vessel an amphiphilic peptide. The peptide may comprise at least thirteen amino acids that may alternate between a hydrophobic amino acid and a hydrophilic amino acid. The peptide may form a beta-sheet spontaneously in an aqueous solution in the presence of a cation. | 2016-10-06 |
20160287745 | DISSOLVABLE HYDROGEL COMPOSITIONS FOR WOUND MANAGEMENT AND METHODS OF USE - The inventions provided herein relate to dissolvable hydrogel compositions and methods of uses, e.g., but not limited to, in wound management. Accordingly, methods for wound management involving the dissolvable hydrogel compositions are also provided herein. In some embodiments, the dissolvable hydrogel composition comprises an adhesive thioester hydrogel, which can facilitate adherence of the dissolvable hydrogen composition to a surface (e.g., a wound) and can be controllably dissolved later upon addition of a thiolate compound to release the dissolvable hydrogel composition from the surface (e.g., the wound). | 2016-10-06 |
20160287746 | RESORBABLE BIOMIMETIC PROSTHETIC LIGAMENT - An artificial ligament prosthesis which is notable in that it comprises a layer totally or partly consisting of PCL fibres. The ligament prosthesis is a biodegradable and “biointegrable” artificial ligament which makes it possible to take away all the apprehensions and uncertainties due to non-degradable synthetic supports. It is a prosthetic structure inspired by and similar to the native tissue, which is biodegradable while being sterilisable. It can optionally be seeded in order to facilitate the formation of functional tissues with controlled cell and tissue activity, having the required mechanical properties. The prosthesis maybe slowly resorbable in order to be gradually replaced with a functional tissue identical to that of the native ligament. | 2016-10-06 |
20160287747 | SHAPED COLLAGEN TISSUE IMPLANT AND METHOD OF MANUFACTURING THEREOF - The invention relates to a shaped collagen tissue implant comprised of collagen molded in a particular shape and methods of manufacture thereof. The shaped tissue implants of the invention generate tissue structures that retain their size, shape, flexibility, and texture after implantation into a patient. | 2016-10-06 |
20160287748 | STERILIZATION PROCESS - The present invention relates to a process for sterilizing implantable biomaterials. In particular, the invention relates to a process for sterilizing collagen-containing implantable biomaterials and storage thereafter. | 2016-10-06 |
20160287749 | RECONSTITUTED AMNIOTIC MEMBRANE-AMNIOTIC FLUID COMBINATION TISSUE GRAFT - The invention relates to preparations and methods of creating preparations of reconstituted amniotic membrane utilizing amniotic fluid, for use as combination tissue grafts in surgical and minimally invasive medical therapy of injury and disease. The preparations maximize available quantities of viable mesenchymal stem cells and non-cellular bioactive compounds to enhance therapeutic efficacy. The tissue graft preparations are liquids and/or semi-viscous fluids which may be intraoperatively transplanted at the recipient site using a needless syringe or by non-operative percutaneous injection through a hypodermic needle. | 2016-10-06 |
20160287750 | STANDARDIZED AMNIOTIC MEMBRANE TISSUE GRAFT - The invention relates to preparations of amniotic membrane-derived tissue grafts standardized for the concentration amniotic membrane and its constituent components by dry weight. The standardized amniotic membrane tissue graft is used by physicians and other healthcare providers in the surgical and minimally invasive medical therapy of a wide range of injuries and disease processes. The preparations maximize available quantities of non-cellular bioactive compounds and viscosity to enhance therapeutic efficacy for the desired application. The standardized amniotic membrane tissue graft preparations are semi-viscous fluids or gels which may be intraoperatively transplanted at the recipient site using a needless syringe, by non-operative percutaneous injection through a hypodermic needle, or by direct application. | 2016-10-06 |
20160287751 | INJECTABLE AMNIOTIC MEMBRANE TISSUE GRAFT - The invention relates to an injectable amniotic membrane tissue graft product for percutaneous, minimally invasive, surgical, and topical therapy of injury and disease and methods of applying such tissue grafts to a subject at a particular location. The injectable preparations maximize and standardize available quantities of non-cellular biological compounds to enhance therapeutic efficacy. The tissue graft preparations are semi-viscous fluids with standardized properties which may be intraoperatively transplanted at the recipient site using a needless syringe, by non-operative percutaneous injection through a hypodermic needle, or direct topical application to open cutaneous wounds and external soft tissue defects. | 2016-10-06 |
20160287752 | RECONSTITUTED AMNIOTIC MEMBRANE-AMNIOTIC FLUID COMBINATION TISSUE GRAFT WITH STANDARDIZED STEM CELL COMPONENT AND METHOD OF FORMING SAME - The invention relates to preparations and methods of creating preparations of reconstituted amniotic membrane utilizing amniotic fluid, for use as combination tissue grafts in surgical and minimally invasive medical therapy of injury and disease. The preparations maximize available quantities of viable mesenchymal stem cells and non-cellular bioactive compounds to enhance therapeutic efficacy. The tissue graft preparations are semi-viscous fluids which may be intraoperatively transplanted at the recipient site using a needless syringe or by non-operative percutaneous injection through a hypodermic needle. | 2016-10-06 |
20160287753 | BONE REGENERATION AGENT - Provided is a bone regeneration agent comprising an inactivated cell construct derived from stem cells as a source material, the inactivated cell construct at least containing a mineral and an extracellular matrix. The bone regeneration agent has osteoconductive and osteoinductive abilities, and is inexpensively producible and size-controllable. Also provided is a method comprising the steps of: | 2016-10-06 |
20160287754 | METHOD FOR PREPARING BILAYER SCAFFOLD THROUGH SINGLE PROCESS AND METHOD FOR REGENERATING TISSUE USING BILAYER SCAFFOLD OBTAINED BY PREPARING METHOD - Disclosed is a method for preparing a bilayer scaffold through single process comprising: preparing a first polymer aqueous solution; adding a second polymer into the first polymer aqueous solution and stirring a reactant; adding a surfactant into the stirred reactant and stirring the reactant at high temperature and high speed; freeze-drying the stirred reactant thereby obtaining a sponge; dipping the sponge in a cross-linking agent thereby rendering be cross-linked; and freeze-drying the cross-linked reactant. | 2016-10-06 |
20160287755 | TISSUE SCAFFOLD MATERIALS FOR TISSUE REGENERATION AND METHODS OF MAKING - Disclosed herein are tissue scaffold materials with microspheres of one density embedded in hydrogel of a different density. The disclosed materials have improved ability to facilitate cellular invasion and vascularization for wound healing and tissue regeneration. The inventors have found that materials having components with different densities promotes invasion of cells, including desirable cells such as fibroblasts and endothelial precursor cells, into the scaffold. | 2016-10-06 |
20160287756 | METHOD OF PRINTING A TISSUE CONSTRUCT WITH EMBEDDED VASCULATURE - A printed tissue construct comprises one or more tissue patterns, where each tissue pattern comprises a plurality of viable cells of one or more predetermined cell types. A network of vascular channels interpenetrates the one or more tissue patterns. An extracellular matrix composition at least partially surrounds the one or more tissue patterns and the network of vascular channels. A method of printing a tissue construct with embedded vasculature comprises depositing one or more cell-laden filaments, each comprising a plurality of viable cells, on a substrate to form one or more tissue patterns. Each of the one or more tissue patterns comprises one or more predetermined cell types. One or more sacrificial filaments, each comprising a fugitive ink, are deposited on the substrate to form a vascular pattern interpenetrating the one or more tissue patterns. The vascular pattern and the one or more tissue patterns are at least partially surrounded with an extracellular matrix composition. The fugitive ink is then removed to create vascular channels in the extracellular matrix composition, thereby forming an interpenetrating vascular network in a tissue construct. | 2016-10-06 |
20160287757 | REDUCING THE DETERIORATON OF WETTED HYDROPHILIC COATINGS COMPRISING WATER SUBJECTED TO STERILIZATION BY RADIATION - A method of reducing the deterioration of a wetted hydrophilic coating comprising water at the time of sterilization by radiation is provided. The method comprises the step of reducing the amount of oxygen in an atmosphere in contact with the wetted hydrophilic coating in addition to any reduction in oxygen provided by oxygen scavengers that may be present in the wetted hydrophilic coating. | 2016-10-06 |
20160287758 | Application Of Antimicrobial Agents To Medical Devices - Invasive medical devices including a substantially non-eluting antimicrobial treatment are disclosed. One or more external and/or internal surfaces of the medical device include a substantially non-eluting copper-coated surface that assists in preventing microbial colonization of the coated surface. This in turn reduces the incidence of infection to the patient originating from the medical device. In one embodiment, a catheter assembly is disclosed and comprises an elongate catheter tube that defines at least one lumen, at least one extension leg including a luer connector, and a bifurcation hub including at least one fluid passageway that provides fluid communication between the extension leg and the lumen. A substantially non-eluting copper coating is disposed on a surface of at least one of the lumen, the extension leg, the luer connector, and the fluid passageway. The coating is applied via an electroless deposition process. A water-shed coating is disposed on the copper coating. | 2016-10-06 |
20160287759 | FLUSHABLE DISINTEGRATION CATHETER - Medical devices that are flushable in a standard toilet are disclosed. The medical devices are made at least in part of material that when introduced into water (of a toilet) disintegrate and/or fragment or are fragmentable before or after introduction into water such that they can be easily carried by the water through the disposal system. At least a portion of the device is intended for insertion into a patient or subject wherein the body-insertable portion retains its structural integrity while in use but is fragmentable once outside the body and exposed to a selected condition. | 2016-10-06 |
20160287760 | ULTRAVIOLET ACTIVATED ANTIMICROBIAL SURFACES - The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings. | 2016-10-06 |
20160287761 | STENT WITH PREFERENTIAL COATING - This invention relates to stents, a type of implantable medical device, with an antiproliferative coating and a prohealing luminal coating and methods of fabricating stents with an antiproliferative coating and a prohealing luminal coating. | 2016-10-06 |
20160287762 | DIGITAL PRESSURE GAUGE - A vacuum pressure regulator system is provided for use in association with a vacuum system in which a vacuum is employed for healthcare purposes, for assisting in monitoring and regulating the vacuum pressure, and having a manual pressure control valve to adjust the treatment vacuum pressure supplied to the patient, a vacuum pressure sensor to sense the treatment vacuum pressure for the patient in the system, and producing a treatment vacuum pressure signal, a sampling circuit which intermittently samples the pressure signal generated by the pressure sensor and generate sampling signals, an electrically powered pressure display circuit, and digital pressure display, for receiving the sampling signals and providing a visible display, and a non-mains power supply. | 2016-10-06 |
20160287763 | Apparatus, Method, And System For Controlling Negative-Pressure Treatment - In one example embodiment, an apparatus for providing negative-pressure therapy may comprise a negative-pressure source, a pressure sensor, and a control valve. The negative-pressure source may be configured to be fluidly coupled to a distribution component. The control valve may be fluidly coupled to the pressure sensor and configured to be selectively coupled to the negative-pressure source, the distribution component, or both. A controller may also be configured to operate the control valve to selectively couple the pressure sensor to at least one of the negative-pressure source and the distribution component through the control valve, and the pressure sensor may provide a feedback signal to the controller indicative of pressure in a feedback path associated with the position of the control valve. The controller may also be configured to operate the negative-pressure source based on the feedback signal. | 2016-10-06 |
20160287764 | BURSITIS TREATMENT DEVICE AND METHOD - A bursitis treatment device ( | 2016-10-06 |
20160287765 | NEGATIVE PRESSURE WOUND CLOSURE DEVICE - The present invention relates to a negative pressure wound closure system and methods for using such a system. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Preferred embodiments can utilize tissue securing portions that aid in securing the invention within a wound. | 2016-10-06 |
20160287766 | BREAST MILK STORAGE SYSTEM - A breast milk storage system which comprises a mandrel for selective engagement with a bottle connector of a breast pump. The storage system also includes at least one clamp in pivotal engagement with the mandrel, and a lock ring. The lock ring is positioned for rotation about the mandrel and the at least one clamp. Rotation of the lock ring effectuates pivoting of the at least one clamp between an open position and a closed position. In the closed position, the at least one clamp is pivoted with respect to the mandrel and presses against the mandrel so as to retain a storage bag in place by pinching said storage bag between the at least one clamp and the mandrel. | 2016-10-06 |
20160287767 | BREASTMILK EXPRESSION SYSTEM WITH DETECTION, FEEDBACK AND CONNECTABILITY FEATURES - Methods and systems for an improved feedback milk extraction system are described. According to aspects, the system may communicate with various electronic devices and/or server components to exchange data and perform certain functionalities. The functionalities may include providing visual and audio feedback to a user, supporting unique kit identification as well as associated user profiles and preferred configuration settings, detecting and responding to leaks having various sizes during operation of the breastpump, controlling operation of the breastpump in response to detected leaks and the detected type and/or magnitude of the leak, preemptively contacting customers if a fault condition is detected or imminent, enabling effective labeling of collection containers, and determining volume and flow of expressed breastmilk. | 2016-10-06 |
20160287768 | WEARABLE MACHINE SYSTEM - A wearable machine system includes a garment and a passive actuator mounted to the garment. The passive actuator is actuatable in response to involuntary movements of a wearer of the garment. A machine is coupled with the passive actuator such that actuation of the passive actuator responsive to the involuntary movements mechanically drives the machine. | 2016-10-06 |
20160287769 | BREAST PUMP SYSTEM AND METHODS - Systems and methods for pumping milk from a breast, wherein the milk is expressed from the breast under suction and milk is expulsed from the pumping mechanism to a collection container under positive pressure. | 2016-10-06 |
20160287770 | IMPLANTABLE CONNECTOR ASSEMBLY AND METHOD OF COMMUNICATING AN ELEMENT TO AN IMPLANTABLE DEVICE - An implantable connector assembly ( | 2016-10-06 |
20160287771 | Hemodynamic Assist Device - A hemodynamic flow assist device includes a miniature pump, a basket-like cage enclosing and supporting the pump, and a motor to drive the pump. The device is implanted and retrieved in a minimally invasive manner via percutaneous access to a patient's artery. The device has a first, collapsed configuration to assist in implantation and a second, expanded configuration once deployed and active. The device is deployed within a patient's aorta and is secured in place via a self-expanding cage which engages the inner wall of the aorta. The device includes a helical screw pump with self-expanding blades. Also included is a retrieval device to remove the hemodynamic flow assist device once it is no longer needed by the patient. Also included is an arterial closure device to close the artery access point after implantation and removal of the hemodynamic flow assist device. The hemodynamic flow assist device helps to increase blood flow in patients suffering from congestive heart failure and awaiting heart transplant. | 2016-10-06 |
20160287772 | METHODS AND APPARATUSES FOR IMPEDANCE-BASED GAS DETECTION FOR MICROFLUIDIC SYSTEMS - Methods and apparatuses for detection of gas bubbles in a microchannel configured for a conductive fluid to flow therethrough. The methods and apparatuses utilize a plate and at least two aligned electrodes embedded within the plate. The plate is configured to be located over the microchannel such that the at least two aligned electrodes are located along a length of the microchannel in the flow direction. Impedance is measured between the electrodes, and the percentage of gas within the fluid flowing through the microchannel is measured based on the measured impedance between the electrodes. | 2016-10-06 |
20160287773 | AUTOMATED PERITONEAL DIALYSIS SYSTEM USING A PERISTALTIC PUMP AND NON-CONTACT SENSORS - An automated peritoneal dialysis therapy device includes pump tubing for delivering dialysate to a patient and for removing waste from the patient; a retractable peristaltic pump assembly; and a processor for controlling operations of the automated peritoneal dialysis therapy device. The retractable peristaltic pump assembly includes a retractable peristaltic pump having a pump rotor and a pump base, a heating source, located in the pump base, to heat the dialysate, a first temperature sensor to measure a temperature of the heating source, a second temperature sensor to measure a temperature of the dialysate, a flow sensor to measure an amount of dialysate being pumped, a pressure sensor to measure a pressure of the dialysate being pumped, and a motor to rotate the pump rotor. The processor controls rotational speed, displacement, and a direction of the pump rotor. | 2016-10-06 |
20160287774 | IMPLANTABLE HEART TREATMENT SYSTEMS, DEVICES, AND METHODS - Treatment of cardiac tissue via an implantable heart treatment device is described. A device embodiment includes, but is not limited to, a substrate configured for implantation within a body; an electromagnetic signal generator coupled to the substrate and configured to generate one or more electric signals configured to stimulate one or more tissues of a heart; and an oxygenator coupled to the substrate and configured to supply one or more oxygenated molecules to one or more tissues of the heart, the oxygenator including a blood inlet portion, a blood outlet portion, and an oxygen exchange portion positioned between the blood inlet portion and the blood outlet portion, the oxygen exchange portion including a high surface area oxygen exchanger configured to transfer one or more oxygenated molecules from the high surface area oxygen exchanger to blood passing from the blood inlet portion to the blood outlet portion. | 2016-10-06 |
20160287775 | IMPLANTABLE HEART TREATMENT SYSTEMS, DEVICES, AND METHODS - Treatment of cardiac tissue via an implantable heart treatment device is described. A device embodiment includes, but is not limited to, a substrate; an electromagnetic signal generator configured to generate one or more electric signals configured to stimulate one or more tissues of a heart; a metabolic molecule supply device configured to supply one or more metabolic molecules to one or more tissues of the heart; and control circuitry operably coupled to the electromagnetic signal generator and the metabolic molecule supply device, the control circuitry configured to generate one or more control signals according to at least a first control protocol and a second control protocol, dependent upon a status of a ventricular fibrillation event of the heart. | 2016-10-06 |
20160287776 | IMPLANTABLE HEART TREATMENT SYSTEMS, DEVICES, AND METHODS - Treatment of cardiac tissue via an implantable heart treatment device is described. A device embodiment includes, but is not limited to, a substrate configured for implantation within a body; an electromagnetic signal generator coupled to the substrate and configured to generate one or more electric signals configured to stimulate one or more tissues of a heart within the body; and an energy-carrier molecule delivery device coupled to the substrate and configured to supply one or more non-oxygen cellular energy sources to one or more tissues of the heart within the body. | 2016-10-06 |
20160287777 | Method and Apparatus for Producing Platelet Rich Plasma - A device and method for producing a portion of platelet rich plasma from a fluid sample obtained from a patient. The device comprises three intercommunicated portions, each portion having an internal chamber defined therein. The fluid sample is first brought into the base portion where it is separated into red blood cells and plasma. The plasma portion of the sample is then withdrawn into the second portion where it is further separated into platelet poor plasma disposed over platelet rich plasma. The portion of platelet poor plasma is then withdrawn from the second chamber, leaving only platelet rich plasma within the second chamber. The base portion also includes a membrane located on its distal end which helps maintain a vacuum within the device when the fluid sample is being initially inserted into base chamber. | 2016-10-06 |
20160287778 | Cell Washing Device Using Standing Acoustic Waves And A Phantom Material - Devices for washing a composition including cells are provided. The devices include a separation channel, a first wave component and a second wave component. The separation channel is positioned between the first and second wave components. Collectively, the wave components generate a standing bulk acoustic wave that isolates cells from the composition. | 2016-10-06 |
20160287779 | SURGICAL FLUID MANAGEMENT SYSTEM - A fluid management system includes a disposable cassette carrying inflow and outflow tubing sections that are configured for releasably mating with a console including a control unit and a pair of roller pump heads. The console may automatically identify the disposable cassette and weigh the fluid in an inflow source. During operation, the system can monitor pressure in the working space, and provide for inflow and outflow control to maintain any desired operating parameters. | 2016-10-06 |
20160287780 | THERAPY-SPECIFIC MEDICAL PUMP - A medical pump provides programming to assist a patient in complying with treatment schedules involving varying dosages of medicament(s). The pump includes stored treatment schedules and protocols that describe control of flow control device(s) for delivering different medicines according to the protocols and which may provide reminders and instructions to the patient | 2016-10-06 |
20160287781 | Compact Intravenous Pump and Medication Container Holder - A compact intravenous pump and medication container holder. The present invention has a substantially flat base having a peripheral edge with one or more sidewalls placed along the edge. The sidewalls are positioned substantially perpendicular to the base, forming an interior adapted to removably secure an intravenous pump. An arm is placed substantially perpendicular to the base on one side thereon and extends upward therefrom. The arm has a first end secured to the base, and a second end having a fastener adapted to support a medication container. A strap is affixed to one side of the base and is adapted to secure an intravenous pump to the base. | 2016-10-06 |
20160287782 | SEALED INFUSION DEVICE WITH ELECTRICAL CONNECTOR PORT - A portable medical device includes an interface for accepting a power supply and enabling data transfer while still connected to a human body. The interface may include a universal serial bus interface and may be coupled to a data isolation chip and a power isolation chip. A power controlling processor may determine how the supplied power, e.g., voltage, is supplied to other components within the infusion device. Additional circuitry within the system may provide a secure power transfer within the device to ensure user safety and ensure that a high frequency noise is properly attenuated. | 2016-10-06 |
20160287783 | IMPLANTABLE DRUG DELIVERY DEVICE WITH A CHECK VALVE - An implantable drug delivery device, comprising a check valve, a locking device, a drug delivery device body capable of being connected to a well-matched catheter through a locking device, wherein the drug delivery device body further comprising a pump frame, a well-matched punctured diaphragm disposed on the top of the pump frame, a pump cover well-matched with pump frame and punctured diaphragm disposed on the top of the punctured diaphragm, the pump cover, punctured diaphragm and pump frame sealingly connected to each other; and a check valve connected to the pump frame, wherein a pump cavity is formed by the pump cover, punctured diaphragm, pump frame and the check valve forming a pump cavity. | 2016-10-06 |
20160287784 | PUMP DELIVERY CALCULATION SYSTEMS AND METHODS - An infusion pump system includes at least one reservoir having a reservoir volume, and an infusion pump including a pumping mechanism operably coupled to the at least one reservoir, a processor including a memory and configured to control operation of the pumping mechanism, and a calculation module configured to determine at least one characteristic about the at least one reservoir. | 2016-10-06 |
20160287785 | IV FLOW MANAGEMENT SYSTEMS AND METHODS - An intravenous delivery system may operate by gravity feed, and may have a liquid source containing a liquid, a drip unit that receives the liquid from the liquid source, and tubing that receives the liquid from the drip unit for delivery to a patient. A flow rate sensor may be used to measure a flow rate of liquid through the intravenous delivery system, and may generate a flow rate signal indicative of the flow rate. A controller may receive the signal, and may compare the flow rate with a desired flow rate. If the flow rate is more or less than the desired flow rate, the controller may transmit a control signal to a flow rate regulator. The flow rate regulator may receive the control signal and, in response, modify the flow rate to bring the flow rate closer to the desired flow rate. | 2016-10-06 |
20160287786 | DRUG ADMINISTRATION CONTROLLER - A drug administration controller has a sensor that generates a sensor signal to a physiological measurement device, which measures a physiological parameter in response. A control output responsive to the physiological parameter or a metric derived from the physiological parameter causes a drug administration device to affect the treatment of a person, such as by initiating, pausing, halting or adjusting the dosage of drugs administered to the person. | 2016-10-06 |
20160287787 | Medicament Delivery Device and Actuation Mechanism for a Drug Delivery Device - Described is an actuation mechanism for a medicament delivery device having a needle with a distal tip. The actuation mechanism comprises an outer sleeve telescopically relative to the delivery device and an inner sleeve telescopically arranged relative to the outer sleeve. The outer sleeve is axially translatable relative to the delivery device, and the inner sleeve is axially translatable relative to the outer sleeve. In a first state, the inner sleeve protrudes distally from the outer sleeve and the outer sleeve protrudes distally from the delivery device. In a second state, the inner sleeve is contained within the outer sleeve. Movement of the outer sleeve proximally relative to the delivery device in the second state initiates delivery of a medicament in the delivery device. | 2016-10-06 |
20160287788 | AUTO-INJECTOR - An auto-injector pen has an outer housing ( | 2016-10-06 |
20160287789 | MEDICAMENT DELIVERY DEVICE SUB-ASSEMBLY - A sub-assembly of a medicament delivery device, the sub-assembly including a housing for containing a propellant source, and a locking ring for attachment to the housing. The housing is configured to receive a flange of a syringe, the locking ring is configured to retain a syringe flange received in the housing between the locking ring and the housing when the locking ring is attached to the housing. | 2016-10-06 |
20160287790 | MEDICAMENT DELIVERY DEVICE SUB-ASSEMBLY - A sub-assembly of a medicament delivery device, the sub-assembly comprising including a propellant source having a reservoir housing defining a reservoir and a stem having a bore therethrough, at least one inlet in fluid communication with the bore, and an open outlet end in fluid communication with the bore, the stein being moveable relative to the reservoir housing between a first position in which the at least one inlet is not in fluid communication with the reservoir and a second position in which the at least one inlet is in fluid communication with the reservoir, the propellant source further including a biasing member for biasing the stem towards the first position. The sub-assembly further including a collet member having a first plurality of radially flexible fingers and a second plurality of radially flexible fingers. | 2016-10-06 |
20160287791 | Medicament Delivery Device - A medicament delivery device includes a housing having a longitudinal axis, a container holder, an axially movable plunger adapted to be displaced along the longitudinal axis into the container holder, and an energy accumulating member arranged inside the housing and adapted for displacing the plunger along the longitudinal axis. The plunger includes an outer plunger rod and an inner plunger rod arranged at least partially inside the outer plunger rod, the inner plunger rod being threadedly engaged with the outer plunger rod and manually rotatable to displace the inner plunger rod along the longitudinal axis into the container holder. | 2016-10-06 |
20160287792 | PLUGGED HYPODERMIC NEEDLE SYSTEM - A needle hypodermic system and method for reducing the incidence of infections due to administering fluids by injection or for reducing the risk of surface contamination of an aspirated sample of blood or other bodily tissue in humans or animals is provided. The hypodermic needle system may include a needle with a plug or film disposed over or within its hollow bore to substantially prevent bacteria, fungi and/or other organisms/contaminants, which may be present on the exterior surface to be penetrated, from adhering to the inner surfaces of the needle's channel or become trapped in the needle bore. A second stylet or needle may be deployed to pierce or push aside the plug. | 2016-10-06 |
20160287793 | HYPODERMIC NEEDLE SYSTEM HAVING PLUNGER - A needle hypodermic system and method for reducing the incidence of infections due to administering fluids by injection or for reducing the risk of surface contamination of an aspirated sample of blood or other bodily tissue in humans or animals is provided. The hypodermic needle system may include a needle with a plug or film disposed over or within its hollow bore to substantially prevent bacteria, fungi and/or other organisms/contaminants, which may be present on the exterior surface to be penetrated, from adhering to the inner surfaces of the needle's channel or become trapped in the needle bore. A second stylet or needle may be deployed to pierce or push aside the plug. | 2016-10-06 |
20160287794 | HYPODERMIC NEEDLE SYSTEM ACTIVATION MECHANISM - A needle hypodermic system and method for reducing the incidence of infections due to administering fluids by injection or for reducing the risk of surface contamination of an aspirated sample of blood or other bodily tissue in humans or animals is provided. The hypodermic needle system may include a needle with a plug or film disposed over or within its hollow bore to substantially prevent bacteria, fungi and/or other organisms/contaminants, which may be present on the exterior surface to be penetrated, from adhering to the inner surfaces of the needle's channel or become trapped in the needle bore. A second stylet or needle may be deployed to pierce or push aside the plug. | 2016-10-06 |
20160287795 | METHOD OF USING A HYPODERMIC NEEDLE SYSTEM - A needle hypodermic system and method for reducing the incidence of infections due to administering fluids by injection or for reducing the risk of surface contamination of an aspirated sample of blood or other bodily tissue in humans or animals is provided. The hypodermic needle system may include a needle with a plug or film disposed over or within its hollow bore to substantially prevent bacteria, fungi and/or other organisms/contaminants, which may be present on the exterior surface to be penetrated, from adhering to the inner surfaces of the needle's channel or become trapped in the needle bore. A second stylet or needle may be deployed to pierce or push aside the plug. | 2016-10-06 |
20160287796 | CARTRIDGE SYSTEM TO WHICH A SYRINGE BODY CAN BE ATTACHED - A needle hypodermic system and method for reducing the incidence of infections due to administering fluids by injection or for reducing the risk of surface contamination of an aspirated sample of blood or other bodily tissue in humans or animals is provided. The hypodermic needle system may include a needle with a plug or film disposed over or within its hollow bore to substantially prevent bacteria, fungi and/or other organisms/contaminants, which may be present on the exterior surface to be penetrated, from adhering to the inner surfaces of the needle's channel or become trapped in the needle bore. A second stylet or needle may be deployed to pierce or push aside the plug. | 2016-10-06 |
20160287797 | HYPODERMIC NEEDLE SYSTEM HAVING A SPACER - A needle hypodermic system and method for reducing the incidence of infections due to administering fluids by injection or for reducing the risk of surface contamination of an aspirated sample of blood or other bodily tissue in humans or animals is provided. The hypodermic needle system may include a needle with a plug or film disposed over or within its hollow bore to substantially prevent bacteria, fungi and/or other organisms/contaminants, which may be present on the exterior surface to be penetrated, from adhering to the inner surfaces of the needle's channel or become trapped in the needle bore. A second stylet or needle may be deployed to pierce or push aside the plug. | 2016-10-06 |
20160287798 | Housing Blank and Activation Member Blank for a Medicament Delivery Device, a Kit Comprising Such Blanks, and a Medicament Delivery Device - A housing blank and an activation member blank for a medicament delivery device are disclosed, with a kit including a housing blank and an activation member blank, and a medicament delivery device assembled from the kit. The housing blank includes a mid portion having a through-opening for receiving a proximal end portion of a medicament container assembly, and first and second legs foldable relative to the proximal end portion. The activation member blank includes a central portion and a first and second arm foldable relative to the proximal end portion. | 2016-10-06 |
20160287799 | Assembly for a Drug Delivery Device - An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state. The assembly is configured such that, in a first state of the assembly, the piston rod guide is in a first axial position relative to the piston rod in which the piston rod interaction feature is arranged to interact with the guide interaction feature to prevent proximal movement of the piston rod with respect to the housing, and wherein, in a second state of the assembly being different from the first state, the piston rod guide is in a second axial position relative to the piston rod, the second axial position being different from the first axial position, wherein, in the second axial position, the piston rod interaction feature and the guide interaction feature are arranged such that proximal movement of the piston rod with respect to the housing is allowed. | 2016-10-06 |
20160287800 | MEDICAL SYRINGE, GASKET USED FOR SYRINGE AND METHOD FOR PRODUCING SAME - In a conventional laminated gasket production method, when a product of a laminated gasket is demolded from a mold, the product is rubbed against the mold and, therefore, minute scratches are formed on a surface of the laminated gasket. These minute scratches are liable to prevent reliable sealing of a liquid drug. The present invention is a method for producing a gasket to be used for a medical syringe and is characterized by including the steps of: preparing a gasket molding mold; molding a gasket having a circumferential surface portion in the mold with the gasket being laminated with a lamination film; and demolding the gasket from the mold, and then forming a groove only in the lamination film circumferentially of the circumferential surface portion of the gasket. | 2016-10-06 |
20160287801 | Medicament Delivery Device - A medicament delivery device includes a housing having proximal and distal ends; a hollow piston plunger within the housing; a telescopic dose drum concentric between the housing and the plunger; and a plunger driver to drive the plunger toward the proximal end having a hollow drive drum sleeve movable within and coupleable to the piston plunger and fixed to the dose drum; an actuator operably connected to the drive drum sleeve; and a stop body for inhibiting rotation of the dose drum and drive drum sleeve when a set dose equals a remaining dose in a medicament container. The drive drum sleeve and piston plunger are operatively coupled such that axial movement of the actuator toward the proximal end forces the drive drum sleeve and piston plunger to couple, whereby the piston plunger and dose drum are displaced toward the proximal end for delivering the set dose. | 2016-10-06 |
20160287802 | DRUG DELIVERY DEVICE WITH DOSE DELIVERY CLICKER - A drug delivery device comprises a lead screw having a longitudinal axis, a distal end and a proximal end that is axially movable in a distal direction relative to a mid-body, the lead screw including a threaded shaft, wherein the lead screw has a keyway positioned parallel to the longitudinal axis and containing a first section of a dose dispensing feedback component; the mid-body being designed to prevent rotation of the lead screw with respect to the mid-body, where the mid-body contains a second section of the dose dispensing feedback component. | 2016-10-06 |
20160287803 | DRUG DELIVERY DEVICE WITH END OF DOSE FEEDBACK - A method and an assembly for providing a drug delivery device is presented. The assembly includes a housing and an end of dose feedback connection provides the user with an audible and/or tactile signal to indicate that the drug delivery is completed. A first section of the end of dose feedback connection is located on a distal portion of an inner sleeve and a second section of the end of dose feedback connection is located on the mid-body. | 2016-10-06 |
20160287804 | Rotary Sensor Assembly with Space Efficient Design - A sensor assembly comprising a first rotary sensor part having a plurality of individual electrically conducting code segments arranged in a circumferential pattern, and a plurality of electrically conducting reference segments between the code segments, and a second rotary sensor part arranged rotationally relative to the first part a plurality of contact structures, each contact structure being arranged to be in contact with either a code segment or a reference segment depending on the rotational position between the first and second rotary sensor part. The contact structures are configured to engage and connect to different sensor segments as the first and second rotary sensor part rotate relative to each, the created connections being indicative of a rotational position between the first and second rotary sensor part. For a given rotational position, at least one contact structure engages a code segment and at least one contact structure engages a reference segment. | 2016-10-06 |
20160287805 | Medicament Delivery Device and Method of Assembling the Same - A device for injecting a medicament includes a housing for a medicament container assembly, and an activation member axially movable relative to the housing between extended and retracted positions with a gripping member. A movement guide mechanism includes a first guide, a second guide that has a locking portion, and a guide follower that slides along the first guide when the activation member moves from the extended position to the retracted position and that slides along the second guide when the activation member moves from the retracted position to the extended position. The gripping member engages the container assembly when the activation member is in the retracted position. The locking portion interacts with the guide follower when the activation member moves from the retracted position to the extended position to restrict movement of the activation member. A method of assembling a delivery device is also disclosed. | 2016-10-06 |
20160287806 | MEMBER AND ASSEMBLY FOR A DRUG DELIVERY DEVICE, DRUG DELIVERY DEVICE AND USE OF A MEMBER | 2016-10-06 |
20160287807 | Rotary Sensor Assembly with Axial Switch and Redundancy Feature - A sensor assembly comprising a first rotary sensor part with a plurality of individual electrically conducting axial position sensor segments arranged in a circumferential pattern, and a second rotary sensor part arranged rotationally relative to the first portion and comprising a plurality of circumferentially arranged electrically interconnected axial position contacts adapted to be arranged in contact with the axial position sensor segments. The assembly further comprises actuator means for axially moving the axial position contacts between a connected and a dis-connected position, wherein the axial position contacts and the axial position sensor segments are arranged such that for a given rotational position at least two axial position contacts each are in contact with a different axial position sensor segment. | 2016-10-06 |
20160287808 | Rotary Sensor Module with Resynchronization Feature - Drug delivery device comprising expelling means allowing a user to set a dose corresponding to a number of increments from an initial state, an indication member adapted to rotate in a first direction corresponding to the set dose, and rotate in an opposed second direction corresponding to an expelled dose, the indication member having an initial rotational position corresponding to both the initial state and the fully expelled dose state. Sensor means having an incremental counter synchronized with the rotational position of the indication member and having a reference point corresponding to the initial rotational position of the indication member. After detecting an error state the sensor means is adapted to re-synchronize by detecting the number of rotational increments for a set dose and for a subsequent expelled dose. If the numbers are identical the reference point is reset corresponding to the current rotational position of the indication member. | 2016-10-06 |
20160287809 | MEDICAL DEVICES AND METHODS FOR CREATING BUBBLES - A dedicated device for detection of vascular shunts can include a first chamber, a second chamber, and a third chamber. The first chamber can be configured to hold liquid, the second chamber to hold gas, and the third chamber can be in communication with the first and second chambers. The third chamber can include small-scale geometric features configured to produce gas bubbles as liquid from the first chamber and gas from the second chamber simultaneously flow into the third chamber. The device can also include a device opening in communication with the third chamber such that a mixture of liquid and gas bubbles can flow out of the device opening. The device can also include a plunger configured to force the liquid and the gas simultaneously from the first and second chambers, through the third chamber to mix with each other and produce bubbles, and further through the device opening. | 2016-10-06 |
20160287810 | DRUG DELIVERY DEVICE HAVING A NEEDLE SHIELD WITH NEEDLE CAP REMOVER - The invention relates to a mg delivery device ( | 2016-10-06 |
20160287811 | INJECTION DEVICES AND METHODS OF USE THEREOF - Medical devices for injecting tissue and methods of use thereof are described. The medical device may comprise a handle, a shaft, and a plurality of needles extending through the shaft, each needle defining a lumen therethrough and being independently moveable along a longitudinal axis of the device to transition from a retracted configuration to an extended configuration. In the extended configuration, a distal portion of each needle may deflect radially outward with respect to the longitudinal axis of the device. The medical device may comprise an end cap coupled to the distal end of the shaft and/or a locking mechanism to selectively lock the needles in the retracted configuration and/or extended configuration. | 2016-10-06 |
20160287812 | Drug Delivery Device with Movable Needle Mount - The present invention provides a drug delivery device ( | 2016-10-06 |
20160287813 | METHOD AND APPARATUS FOR APPLYING AN ANESTHETIC AND BACTERICIDE - A method and an apparatus for applying an anesthetic includes a receptacle having an upper end, a substantially hollow interior, a lower end having a tube or nozzle extending therefrom, and an attachment for attaching to the barrel of a syringe or vice versa. The receptacle receives a container or canister containing an endothermic gas or vapor (propellant) that rapidly absorbs heat when released to the atmosphere. A depressible actuating member or trigger propels the gas or vapor through an outlet nozzle that is oriented to project a stream of gas or vapor along a delivery axis that intersects a delivery axis of the needle, therefore, the gas or vapor can be successively delivered to an injection site with minimal repositioning of the housing. | 2016-10-06 |
20160287814 | MEDICAL ILLUMINATION DEVICE - A device for locating blood vessels of a patient includes at least one illumination strip including a top surface and a bottom surface. There is a securing device connected to the at least one illumination strip and configured to affix the bottom surface to the patient's skin. There is a light source disposed along the at least one illumination strip and directed toward an area on the patient's skin adjacent to the at least one illumination strip to illuminate the area on the patient's skin and enhance visibility of the patient's blood vessels. | 2016-10-06 |
20160287815 | PHARMACEUTICAL INJECTION DEVICE, AND METHOD FOR CONTROLLING PHARMACEUTICAL INJECTION DEVICE - A pharmaceutical injection device may comprise a main body case having a cartridge holder, a piston that pushes out the pharmaceutical of a pharmaceutical cartridge held in the cartridge holder, a light emitting component, a light receiving component, and a controller. The light emitting component may shine light of different colors on the pharmaceutical cartridge disposed in the cartridge holder. The light receiving component receives light that has been shined from the light emitting component onto the pharmaceutical cartridge and reflected by the pharmaceutical cartridge. The controller may shine from the light emitting component and identify the type of pharmaceutical cartridge. | 2016-10-06 |
20160287816 | Vaporizer - A vaporizer comprising a mouthpiece, atomizer and battery. The atomizer preferably includes an upper chamber and a lower chamber disposed directly below the upper chamber. The upper chamber is preferably the shape of part of an oval cone and the lower chamber is preferably the shape of an oval cylinder. A heat source is disposed in the lower chamber, preferably running lengthwise along the longest diameter of the oval cross-section of the lower chamber. The atomizer is detachable connectable to the battery's housing, facilitating an electrical connection between the atomizer and the battery. | 2016-10-06 |