40th week of 2021 patent applcation highlights part 29 |
Patent application number | Title | Published |
20210310036 | METHOD OF DETECTING BACTERIUM OF GENUS HELICOBACTER USING ABSORBENT SWAB AND APPLICATION THEREOF - A method of detecting a bacterium of the genus | 2021-10-07 |
20210310037 | APPARATUS FOR MICROBIAL ACTIVITY DETECTION AND INVENTORY MANAGEMENT, AND PROCESS THEREOF - A system and method for the real time determination of microbial growth in or on perishable products. The system can predict the extent of microbial growth, e.g., whether food is spoiled, in real time by measuring chemicals released, e.g., CO | 2021-10-07 |
20210310038 | DEVICES AND ASSAYS FOR ESTIMATING MICROBIAL LOAD AND DIFFERENTIATING MICROBIAL POPULATIONS - Devices, methods, kits and means for easy, accurate, and fast estimation of soil microbial load, including fungal load, and fungal to bacterial ratio are described. The methods include extracting soil biomass into an extraction fluid to obtain a soil extract and detecting the fungal fraction, the bacterial fraction, and the fungal to bacterial ratio in the soil extract. The devices typically include microBIOMETER®, devices for particle size discrimination, and devices for absorbance and reflectance detection. The difference in microscopic sizes or spectroscopic absorbance of the fungal particles relative to those of the bacterial particles is used to compute the contribution of each type of particle to the biomass. In one example, the relative coverage of the microBIOMETER® device membrane by the fungal and/or bacterial particles can be measured by and then calculated using a cell phone camera and application. | 2021-10-07 |
20210310039 | MEMBRANE PROTEIN ACTIVITY MEASUREMENT METHOD - The present invention provides a comprehensive assay capable of comprehensively measuring interactive factors for a variety of different types of proteins. In the present invention, provided is a system for detecting activation of a protein by integrating, with mediation of a plurality of factors, changes in the transcriptional regulatory region of a gene whose expression is changed by activation of the protein. The stimulation response ratio of transcription activity before and after stimulation by ligands possessed by individual transcriptional regulatory regions is synergistically integrated, so that a highly sensitive reporter assay system can be constructed. | 2021-10-07 |
20210310040 | SUSCEPTIBILITY AND RESISTANCE OF MICROORGANISMS - Devices, systems, and methods for species and/or strain specific identification and assessment of susceptibility of microorganisms based on the response of sensors in a colorimetric sensor array to metabolic products of the microorganism. An exemplary method according to an embodiment of the present disclosure can include culturing a sample that contains microorganisms. The sample can be in a medium which is exposed to a colorimetric sensor array. A test substance can be introduced to the sample. The method can assess a susceptibility of the microorganisms to the test substance based on a change in at least one sensor in the colorimetric sensor array. Sensors in the colorimetric sensor array can change in response to volatile organic compounds produced by the microorganisms after addition of the test sub stance. | 2021-10-07 |
20210310041 | MODULAR PARALLEL/SERIAL DUAL MICROFLUIDIC CHIP - A system for testing a treatment agent for a biologic material includes an input for receiving a biologic sample. A plurality of micro-pumps pump a portion of the biologic sample from the first reservoir into a connected module. A first module includes a first plurality of testing pathways for testing a first portion of the biologic sample. A first module connector removeably connects the first module to the distributor module. A second module includes a second plurality of testing pathways for testing a second portion of the biologic sample. The selected pathway applies at least one dosage level of a treatment agent to the second portion of the biologic sample. A second module connector removeably connects the second module to the distributor module, wherein treatment agent and the plurality of dosage levels tested by the system may be selected by selecting the second module associated with the second module connector. | 2021-10-07 |
20210310042 | SAMPLING METHOD AND KIT FOR HISTAMINE MEASUREMENT - An object of the present invention is to provide a convenient sampling method and kit for histamine measurement. The present invention provides a method and a kit which involve non-invasively sampling a specimen, and detecting histamine from the obtained sample. | 2021-10-07 |
20210310043 | QUANTIFICATION METHOD OF ETHANOLAMINE PHOSPHATE, OXIDOREDUCTASE FOR QUANTIFICATION, COMPOSITION FOR QUANTIFICATION, KIT FOR QUANTIFICATION AND SENSOR FOR QUANTIFICATION - There is provided a novel quantification method for quantifying a concentration of EAP, which is a biomarker of depression, an enzyme for quantitation, a composition for quantitation, a kit for quantitation or a sensor for quantitation. There is provided a quantification method of ethanolamine phosphate by adding oxidoreductase to a sample containing ethanolamine phosphate. A mediator may be reduced by adding the oxidoreductase, and the reduced mediator may be reacted with a reagent to determine a concentration of ethanolamine phosphate. In addition, hydrogen peroxide produced by adding the oxidase as the oxidoreductase may be reacted with a reagent to determine a concentration of the ethanolamine phosphate. | 2021-10-07 |
20210310044 | ANTIBODY OR APTAMER CONJUGATED-POLYNUCLEOTIDES AND DETECTION METHODS AND MICROFLUIDICS DEVICES USING THE SAME - The disclosure relates to antibody conjugates comprising an antibody linked to a polynucleotide, aptamer conjugates comprising an aptamer linked to a polynucleotide, and methods for detecting a marker or several markers in a sample by using said antibody and aptamer conjugates. The present disclosure also relates to microfluidics devices for detecting markers in a sample. The present disclosure further relates to methods for detecting a microorganism or several microorganisms in a sample and a microfluidics device to be used to detect such microorganisms. | 2021-10-07 |
20210310045 | PROCESS AND COMPOSITION FOR THE STABILIZATION OF CELL-FREE NUCLEIC ACIDS AND CELLS - The invention relates to a composition for use as a stabilizer and a method for stabilizing biological samples, in particular of whole blood, in particular for stabilizing the content and the integrity of cell-free nucleic acids. The composition has, in aqueous solution, at least one buffer substance, which buffers to a pH value of 7 or less, preferably 3.5 to 7.0, at least one chelating agent for divalent cations and urotropine, optionally PEG, or consists thereof. | 2021-10-07 |
20210310046 | METHODS AND KITS FOR LABELING CELLULAR MOLECULES - Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. | 2021-10-07 |
20210310047 | Reaction Mixture, Method and Kit for Performing a Quantitative Real-Time PCR - A reaction mixture for providing a reaction batch for performing a quantitative real-time PCR contains at least one target DNA, which at least in parts corresponds to the DNA section being quantified, at least one reference DNA of defined sequence and in a defined amount, at least two different fluorescent probes of different sequence which generate a signal at different wavelengths, primers, deoxynucleotides and a DNA polymerase. The target DNA and the reference DNA have the same primer binding sites and different probe binding sites. At least one of the fluorescent probes is intended for binding to a section of the target DNA outside the primer binding sites in the amplicon, and at least one of the fluorescent probes is intended for binding to a section of the reference DNA outside the primer binding sites in the amplicon. | 2021-10-07 |
20210310048 | METHOD FOR GENERATING SINGLE-STRANDED CIRCULAR DNA LIBRARIES FOR SINGLE MOLECULE SEQUENCING - The invention comprises circular single-stranded templates for nucleic acid sequencing, methods of making and using the same. | 2021-10-07 |
20210310049 | REAGENTS AND METHODS FOR BLOCKING NON-SPECIFIC INTERACTIONS WITH NUCLEIC ACIDS - Methods and reagents for blocking non-specific interactions with nucleic acids are disclosed. In particular, the invention relates to multi-valent blockers comprising multiple negatively charged polymers or materials attached to a common scaffold and their use in blocking non-specific interactions with nucleic acids. | 2021-10-07 |
20210310050 | IDENTIFICATION OF GLOBAL SEQUENCE FEATURES IN WHOLE GENOME SEQUENCE DATA FROM CIRCULATING NUCLEIC ACID - Techniques for identification of global cancer-specific sequence features in whole genome sequence data obtained from cell-free DNA (cfDNA) samples. An exemplary technique includes obtaining a plurality of whole genome sequencing reads from a cfDNA sample and determining two or more metrics from at least a majority of the plurality of genome sequencing reads, where a first metric of the two or more metrics is: (i) a fragment size of the cell free DNA, (ii) relative read depth of the plurality of whole genome sequencing reads, or (iii) germline allelic imbalance. The technique further includes inputting the two or more metrics into a classifier to obtain a first prediction for a first class and a second prediction for a second class, and classifying the sample of cell free DNA as the first class or the second class based on the first prediction and the second prediction. | 2021-10-07 |
20210310051 | SYSTEMS AND METHODS FOR CHARACTERIZING COMPOSITIONS COMPRISING FECAL-DERIVED BACTERIAL POPULATIONS - In one embodiment, the present invention provides a method for characterizing a first composition comprising a fecal-derived bacterial population, comprising the steps of: obtaining a live culture of the first composition comprising a fecal-derived bacterial population, supplying factors that selectively expand the at least one bacterial strain at a level below a threshold for detection above the threshold level by seeding a chemostat containing culture medium with a second composition comprising a fecal-derived bacterial population; adding the live culture of the first composition comprising a fecal-derived bacterial population to the seeded chemostat, and culturing the first composition comprising a fecal-derived bacterial population with the second composition comprising a fecal-derived bacterial population in the chemostat for a time sufficient to expand the at least one bacterial strain; removing a sample of the chemostat culture; and identifying the at least one bacterial strain. | 2021-10-07 |
20210310052 | METHODS AND SYSTEMS FOR THERAPEUTIC AGENT ANALYSIS - The present disclosure provides methods and systems for analyzing agents (e.g., therapeutic agents) in a biological sample having a three-dimensional matrix. | 2021-10-07 |
20210310053 | METHODS AND SYSTEMS FOR TARGET SCREENING - The present disclosure provides a method for identifying a nucleic acid, which may comprise incubating a cell that has been or is suspected of having been transfected or transduced with an exogenous ribonucleic acid (RNA) molecule or an exogenous deoxyribonucleic (DNA) molecule. Next, a morphological change of the cell may be identified. Next, contents of the cell may be processed to identify a nucleic acid sequence or a peptide, polypeptide, or protein or a sequence of the peptide, polypeptide, or protein. Next, the nucleic acid sequence or the peptide, polypeptide, or protein or the sequence of the peptide, polypeptide, or protein may be analyzed to determine an exogenous sequence of the exogenous RNA molecule or the exogenous DNA molecule. Next, the exogenous sequence of the exogenous RNA molecule or the exogenous DNA molecule may be identified as effecting the morphological change of the cell. The exogenous RNA molecule or the exogenous DNA molecule may encode genes or peptides, polypeptides, or proteins that inhibit, activate, or modulate a biochemical pathway within the cell, thereby causing the morphological change of the cell. | 2021-10-07 |
20210310054 | CUSTOMIZED SKIN CARE PRODUCTS AND PERSONAL CARE PRODUCTS BASED ON THE ANALYSIS OF SKIN FLORA - Embodiments of the present invention relate to a combination of experimental and computational workflows that allow characterization of skin and subcutaneous tissue microbial flora and its associated metabolome, aiming to first evaluate an individual's skin and subcutaneous tissue to determine if any skin condition is as a result of an imbalance or absence of commensal or mutualistic microorganisms or their associated metabolites. In particular, embodiments of the methods and the associated computational platform provided herein relate to conducting a customized or personalized test and obtaining customized or personalized information regarding the skin and subcutaneous tissue flora and its associated metabolome there from. This may be accomplished by simultaneously identifying hundreds of microorganisms or metabolites on an individual's skin and subcutaneous tissue and comparing the resulting profile to a previously compiled healthy profile from our database of skin profiles. An individual's profile provides the basis of a proprietary probiotic skin care product and personal care products that either maintains a health profile or shifts the individual's skin and subcutaneous tissue flora or its associated metabolome close to a healthy profile, at the same time enhancing the synergies between the microbial flora and host's immune system. | 2021-10-07 |
20210310055 | SYSTEMS AND METHODS FOR IDENTIFYING SEQUENCE INFORMATION FROM SINGLE NUCLEIC ACID MOLECULE MEASUREMENTS - Systems and methods for identifying sequence information from measurements made on single nucleic acid molecules are disclosed. The systems and methods can include binding portions of nucleic acid molecules with marker molecules, such as fluorescent molecules and/or intercalating molecules. The marker molecules provide a detectable signal that includes information about the underlying genomic information of the location on the nucleic acid molecule where a given marker molecule is bound. A profile of the detectable signal along a position of the nucleic acid is acquired for multiple different nucleic acid molecules. The PRIMR algorithm processes the data to provide a consensus profile from which a consensus underlying genomic information can be determined. | 2021-10-07 |
20210310056 | REAL-TIME MULTIPLEXED HYDROLYSIS PROBE ASSAY USING SPECTRALLY IDENTIFIABLE MICROSPHERES - Methods and compositions for the detection and quantification of nucleic acids are provided. In one embodiment, a sample is contacted with a primer and a quencher-probe complementary to a target nucleic acid. The quencher-probe is complementary to an anti-probe that comprises a reporter and is attached to a solid support. Thus, hybridized probe is cleaved with a nucleic acid polymerase having exonuclease activity to release the quencher from the probe. The presence of the target nucleic acid is then detected and/or optionally quantified by detecting an increase in signal from the fluorescent reporter on the solid support. | 2021-10-07 |
20210310057 | KINETICALLY PROGRAMMED SYSTEMS AND REACTIONS FOR MOLECULAR DETECTION - The present disclosure concerns detection systems which are kinetically controlled. In the systems of the present disclosure, the systems are kinetically controlled by a first association constant (k | 2021-10-07 |
20210310058 | METHODS AND COMPOSITIONS FOR VIRAL NANO-FISH - Disclosed herein are methods of detecting a target viral nucleic acid sequence, determining the localization of the target viral nucleic acid sequence, and/or quantifying the number of target viral nucleic acid sequences in a cell. This method may be used on small target nucleic acid sequences, and may be referred to as Nano-FISH or viral Nano-FISH. | 2021-10-07 |
20210310059 | COMPOSITIONS, METHODS AND KITS FOR DETECTING MYCOPLASMA GENITALIUM - The present disclosure relates to oligonucleotides useful for determining the presence of | 2021-10-07 |
20210310060 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF COVID 19 - Described herein are methods and compositions related to the diagnosis and treatment of COVID 19 and the detection of SARS-Cov-2. | 2021-10-07 |
20210310061 | DNA AMPLIFICATION METHOD FOR PROBE GENERATION - Disclosed herein are compositions and methods for isothermal amplification of dsDNA without the use of primers. The dis-closed compositions and methods may be used for the generation of probes used in hybrid-capture techniques that usually precede sequencing. Methods of using the probes for capturing target DNA are also provided. | 2021-10-07 |
20210310062 | METHODS FOR THE AMPLIFICATION OF BISULFITE-TREATED DNA - The methods, compositions, and kits of the disclosure provide a novel approach for a whole genome, unbiased DNA analysis method that can be performed on limited amounts of DNA. can be used to analyze DNA to determine its modification status. Aspects of the disclosure relate to a method for amplifying bisulfite-treated deoxyribonucleic acid (DNA) molecules comprising: (a) ligating an adaptor to the DNA molecules, wherein the adaptor comprises a RNA polymerase promoter comprising bisulfite-protected cytosines; (b) treating the ligated DNA molecules with bisulfite; (c) hybridizing the bisulfite-treated DNA molecules with a primer; (d) extending the hybridized primer to make double stranded DNA; and (e) in vitro transcribing the double-stranded DNA to make RNA. | 2021-10-07 |
20210310063 | USE OF DROPLET SINGLE CELL EPIGENOME PROFILING FOR PATIENT STRATIFICATION - An aspect of the invention relates to a method for the diagnosis and/or prognosis of drug resistance, wherein single cell chromatin states are profiled in cells obtained from a subject by using a microfluidic system, the method comprising the steps of: a. providing at least a droplet of first type, wherein said droplet of first type comprises i. a biological element, ii. a lysis buffer, and iii. a nuclease, b. collecting said droplet of first type under conditions that temporarily inactivate said nuclease, c. incubating said droplet of first type, thereby reactivating said nuclease, d. providing at least a droplet of second type, wherein said droplet of second type comprises a nucleic acid sequence, e. merging said droplets of first and second type, thereby generating a droplet of third type, f. incubating said droplet of third type, thereby linking said nucleic acid sequence to one or more genomic region(s) of interest, g. sequencing said one or more genomic region(s) of interest. A further aspect of the present invention relates to a nucleic acid sequence comprising: a. at least one index sequence, b. a sequencing adaptor, and c. at least one protecting function positioned at 3′- and/or 5′-end. | 2021-10-07 |
20210310064 | ELECTRICAL ENHANCEMENT OF BILAYER FORMATION - A method of forming a plurality of lipid bilayers over an array of cells in a nanopore based sequencing chip is disclosed. Each of the cells comprises a well. A salt buffer solution is flowed over the array of cells in the nanopore based sequencing chip to substantially fill the wells in the cells with the salt buffer solution. A lipid and solvent mixture is flowed over the array of cells to deposit the lipid and solvent mixture over at least some of the wells in the cells. A first portion of the cells, each having a lipid bilayer over its well, is detected. A second portion of the cells, each having a lipid membrane but not a lipid bilayer over its well, is detected. An electrical lipid-thinning stimulus is selectively applied to the second portion of the cells but not to the first portion of the cells. | 2021-10-07 |
20210310065 | METHODS AND SYSTEMS FOR ANALYZING IMAGE DATA - Methods and systems for analysis of image data generated from various reference points. Particularly, the methods and systems provided are useful for real time analysis of image and sequence data generated during DNA sequencing methodologies. | 2021-10-07 |
20210310066 | SYSTEM AND METHODS FOR ELECTROKINETIC LOADING OF SUB-MICRON-SCALE REACTION CHAMBERS - Apparatus and techniques for electrokinetic loading of samples of interest into sub-micron-scale reaction chambers are described. Embodiments include an integrated device and related apparatus for analyzing samples in parallel. The integrated device may include at least one reaction chamber formed through a surface of the integrated device and configured to receive a sample of interest, such as a molecule of nucleic acid. The integrated device may further include electrodes patterned adjacent to the reaction chamber that produce one or more electric fields that assist loading the sample into the reaction chamber. The apparatus may further include a sample reservoir having a fluid seal with the surface of the integrated device and configured to hold a suspension containing the samples. | 2021-10-07 |
20210310067 | METHODS AND SYSTEMS FOR MONITORING ORGAN HEALTH AND DISEASE - Methods, compositions, and systems are provided for monitoring tissue and organ health. The methods, compositions, and systems provided herein extract locus specific copy number signals from cell free DNA (cfDNA) samples to identify tissue-specific cfDNA copy number profiles and enable quantification of tissue fractions in the cfDNA samples. | 2021-10-07 |
20210310068 | COMPOSITIONS AND METHODS FOR DETECTING ALLOGENEIC MATTER IN A SUBJECT - The present disclosure provides a panel of nucleic acid molecule primers specific for HLA-specific alleles and other genetic polymorphisms, which are useful for quantitatively amplifying these markers to detect, diagnose, and monitor individuals who have or are at risk of certain disease conditions, such as autoimmune disease, proliferative disease, infectious disease, allograft rejection, or pregnancy-related pathologies. | 2021-10-07 |
20210310069 | METHODS FOR DETERMINING GENE-ALPHA TOCOPHEROL INTERACTIONS - Method for predicting the change in the level of at least one pro-inflammatory cytokine in an individual due to alpha tocopherol supplementation are provided, as well as methods for predicting the response of an individual to alpha tocopherol supplementation, and methods of nutrigenetic screening of an individual. | 2021-10-07 |
20210310070 | ASSESSING INFECTION RISK TO HUMANS - The present disclosure provides methods for assessing the risk of infection to humans posed by a surface or air in a built environment or on an object. In addition to testing for the presence of infectious agents, the methods include the generation and analyses of microbiomes, and the use of both in risk assessment. | 2021-10-07 |
20210310072 | METHOD FOR SCREENING FOR SKIN WHITENING AGENT BY USING SDF1 PROMOTER REGION - A method of screening a skin whitening agent uses the stromal cell-derived factor 1 (SDF1) promoter region, the correlation between the expression amount of the skin pigment and the expression of the SDF1 promoter is observed and thus it is expected to be available in systems for pre-screening pigmentation substances and pigment reduction materials, and the drugs screened by the method is used for treatment of skin pigment-related diseases. | 2021-10-07 |
20210310073 | A GENETIC PREDISPOSITION TO LIVER DISEASE - Embodiments of the disclosure concern a genetic signature for individuals suspected of having liver disease, including end stage liver disease. In particular embodiments, the genetic signature comprises two different genetic markers, including a polymorphism and differential probe hybridization. In specific embodiments, the polymorphism is the rs4567 SNP in the 3′ UTR of the MAN1B1 and the copy number variation is in chromosome 22. | 2021-10-07 |
20210310074 | PROGNOSTIC AND PREDICTIVE TRANSCRIPTOMIC SIGNATURES FOR UTERINE SEROUS CARCINOMAS - The application provides methods of prognosing and classifying uterine serous carcinoma (USC) patients into poor survival groups or good survival groups and for predicting response to therapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application. | 2021-10-07 |
20210310075 | Cancer Classification with Synthetic Training Samples - Methods and systems for detecting cancer and/or determining a cancer tissue of origin are disclosed. A multiclass cancer classifier is disclosed that is trained with a plurality of biological samples containing cfDNA fragments and at least one synthetic training sample generated from the biological samples. The analytics system generates the synthetic training sample by sampling fragments from a training sample labeled as cancer and sampling fragments from another training sample labeled as non-cancer. The sampling probability is determined based on a limit of detection of the cancer classifier, e.g., in order to generate synthetic training samples with cancer tumor fraction proximate to the limit of detection. | 2021-10-07 |
20210310076 | METHODS OF MONITORING CONDITIONS BY SEQUENCE ANALYSIS - There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer. Provided herein are methods for using DNA sequencing to identify personalized biomarkers in patients with autoimmune disease and other conditions. Identified biomarkers can be used to determine the disease state for a subject with an autoimmune disease or other condition. | 2021-10-07 |
20210310077 | KIT, DEVICE AND METHOD FOR DETECTING PROSTATE CANCER - This invention provides a kit or device for detection of prostate cancer and a method for detecting prostate cancer. This invention provides a kit or device for detection of prostate cancer comprising a nucleic acid capable of specifically binding to an miRNA in a sample from a subject or a complementary strand thereof and a method for detecting prostate cancer comprising measuring the miRNA in vitro. | 2021-10-07 |
20210310078 | METHOD FOR EARLY DIAGNOSIS OF BREAST CANCER AND MONITORING AFTER TREATMENT USING LIQUID BIOPSY MULTI-CANCER GENE BIOMARKERS - The present invention relates to a method for early diagnosis and post-treatment monitoring for each molecular subtype of breast cancer using liquid biopsy multiple gene biomarkers, and more particularly, to a non-invasive method for early diagnosis and post-treatment monitoring for breast cancer and each molecular subtype of breast cancer using exosomes. That is, the present inventors have developed a technology for analyzing mRNA inside the exosome, and determined that the accuracy and reproducibility of diagnosis can be improved through the above technology. As such, through the minimal multiple cancer gene biomarker technology applicable to the early diagnosis of breast cancer according to the each molecular subtypes, a method for early diagnosis of breast cancer according to four molecular subtypes thereof, a method of determining the degree of breast cancer progression depending on the degree of expression levels, and the like can be provided. Thus, the present invention can be widely used in the development of a method for early diagnosis of breast cancer using liquid biopsy multiple cancer gene biomarkers and a medical instrument for ex-vivo gene diagnosis for monitoring recurrence after treatment of breast cancer. | 2021-10-07 |
20210310079 | METHODS AND MATERIALS FOR ASSESSING HOMOLOGOUS RECOMBINATION DEFICIENCY - This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an HRD signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided. | 2021-10-07 |
20210310080 | Composition for diagnosing cancer using potassium channel proteins - This disclosure relates to a composition for diagnosing cancer by using potassium channel proteins; to a kit for diagnosing cancer comprising the composition; and to an information providing method for diagnosing cancer. Specifically, the composition or kit for diagnosing cancer provided in this disclosure may be used to diagnose the onset of cancer regardless of its type, by measuring the expression levels of potassium channels, KCa3.1 channel and KCa2.3 channel, or a regulator thereof from vascular endothelial cells treated with a sample of a subject, or from red blood cells isolated from the subject, and thus can be widely utilized in determining the stages of progression (growth, metastasis, prognosis, and recurrence) of various cancers. | 2021-10-07 |
20210310081 | OLIGONUCLEOTIDE PROBE FOR THE SPECIFIC DETECTION OF MICROORGANISMS, CORRESPONDING METHOD AND USE - An oligonucleotide probe combination ( | 2021-10-07 |
20210310082 | TOBACCO TRANSGENIC EVENT AND METHODS FOR DETECTION AND USE THEREOF - Collagen producing plant events, DNA molecules for detecting same and uses thereof in plant breeding methods are provided. | 2021-10-07 |
20210310083 | Methods and Systems for Detection of Pathogens - Disclosed are methods, compositions and systems for detecting the presence or absence of a pathogen in a sample. The method may include the steps of obtaining a sample from the subject and treating the sample with heat to inactivate any pathogen present in the sample. The method may further include the step of treating the sample to concentrate any pathogen present in the sample. Also, the method may include isolate a pathogen-specific nucleic acid from the heat-inactivated sample and detecting the presence or absence of the isolated pathogen-specific nucleic acid. In certain embodiments, the methods and/or systems may be used to detect SARS-CoV-2. The method may employ real time RT-PCR to provide results in about 3 hours or less. | 2021-10-07 |
20210310084 | CELL-FREE NUCLEIC ACIDS FOR THE ANALYSIS OF THE HUMAN MICROBIOME AND COMPONENTS THEREOF - Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like. | 2021-10-07 |
20210310085 | CELL-FREE NUCLEIC ACIDS FOR THE ANALYSIS OF THE HUMAN MICROBIOME AND COMPONENTS THEREOF - Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like. | 2021-10-07 |
20210310086 | PROCESSING OF LIGNOCELLULOSIC BIOMASS - Lignocellulosic biomass ( | 2021-10-07 |
20210310087 | SEMI-CRYSTALLINE FRUCTOSE IN SOLID FORM AND PROCESS FOR MANUFACTURING THE SAME - A fructose in solid form containing a matrix and a plurality of carbohydrate crystals within said matrix, the matrix containing amorphous fructose and water, wherein the carbohydrate crystals comprise fructose and optionally one or more other carbohydrate(s), and optionally wherein the fructose in solid form is coated with a dry powder coating. | 2021-10-07 |
20210310088 | METHODS AND SYSTEMS FOR PROCESSING SUGAR MIXTURES AND RESULTANT COMPOSITIONS - A method including: (a) selectively reacting a first sugar in a mixture which includes at least one second sugar to form a product mixture comprising a product of said first sugar; (b) separating said product of said first sugar from said product mixture; and (c) separating at least one of said at least one second sugar from said product mixture. | 2021-10-07 |
20210310089 | PROCESS AND SYSTEM FOR EXTRACTION OF IRON OXIDE FROM ORE - A method and system of extracting iron oxide from ore is provided, which may include adding a chelating agent to an iron ore to form an iron ore and chelating agent solution, heating the solution to reflux in water, and filtering the solution to yield an extraction residue and a chelated iron solution. The chelated iron solution may be treated with a potassium hydroxide and water solution to yield iron hydroxide. | 2021-10-07 |
20210310090 | PROTECTIVE MASK BY TWO MATERIAL ADDITIVE MANUFACTURING, AND RELATED METHOD - A protective mask for a part, the part including a plurality of openings in a surface thereof, is provided. The protective mask includes a mounting member at least partially within each of at least two of the plurality of openings. Each mounting member includes a water soluble material. A masking member couples the at least two mounting members. The masking member includes a non-water soluble material. Each mounting member includes a first plurality of integral layers of the water soluble material, and the masking member includes a second plurality of integral layers of the non-water soluble material. The protective mask can be made by a two material additive manufacturing system. A related method is also provided. | 2021-10-07 |
20210310091 | ELECTRIC RESISTANCE WELDED STEEL PIPE OR TUBE - Provided is an electric resistance welded steel pipe or tube that develops no quench cracks despite having carbon content of 0.40% or more and has excellent fatigue strength. An electric resistance welded steel pipe or tube comprises: a chemical composition containing, in mass %, C: 0.40% to 0.55%, Si: 0.10% to 1.0%, Mn: 0.10% to 2.0%, P: 0.10% or less, S: 0.010% or less, Al: 0.010% to 0.100%, Cr: 0.05% to 0.30%, Ti: 0.010% to 0.050%, B: 0.0005% to 0.0030%, Ca: 0.0001% to 0.0050%, and N: 0.0005% to 0.0050%, with a balance consisting of Fe and inevitable impurities; and a ferrite decarburized layer at each of an outer surface and an inner surface, the ferrite decarburized layer having a depth of 20 μm to 50 μm from the surface. | 2021-10-07 |
20210310092 | THIN STEEL SHEET AND METHOD FOR MANUFACTURING THE SAME - A thin steel sheet has a steel structure which has a ferrite area fraction of 30% or less, a bainite area fraction of 5% or less, a martensite and tempered martensite area fraction of 70% or more, and a retained austenite area fraction of 2.0% or less and in which the ratio of the dislocation density in the range of 0 μm to 20 μm from a surface of the steel sheet to the dislocation density of a through-thickness central portion of the steel sheet is 90% to 110% and the average of the top 10% of the sizes of cementite grains located in a depth of up to 100 μm from a surface of the steel sheet is 300 nm or less. The maximum camber of the steel sheet sheared to a length of 1 m in a longitudinal direction of the steel sheet is 15 mm or less. | 2021-10-07 |
20210310093 | HOT ROLLED STEEL SHEET WITH ULTRA-HIGH STRENGTH AND IMPROVED FORMABILITY AND METHOD FOR PRODUCING THE SAME - A hot rolled high strength steel sheet with improved formability, including of the following elements in weight %:0.13-0.35 C; 0.80-3.50 Mn; 0.01-2.50 Si; 0.02-1.00 Al; wherein the sum of Si and Al is 0.52-2.50; and optionally one or more selected from: 0.0002-0.0030 Ca; 0.0004-0.0100 REM; 0.10-1.00 Cu; 0.10-1.50 Cr; 0.10-1.00 Ni; 0.05-0.50 Mo; 0.0005-0.0050 B; 0.010-0.100 Nb; 0.010-0.100 Ti; 0.020-0.200 V; wherein the sum of Nb+Ti+V is 0-0.250 and wherein the sum of Cr+Ni+Cu+Mo is 0-1.50, and at most 0.100 P; at most 0.050 S; at most 0.0100 N; the balance inevitable impurities and Fe, wherein the hot rolled high strength steel sheet has a complex phase microstructure including in vol. %:65% or more of a matrix of a mixture of carbide free bainitic ferrite (BF) and/or tempered martensite (TM), and 5 to 25% of retained austenite (RA). | 2021-10-07 |
20210310094 | HIGH-STRENGTH STEEL SHEET AND METHOD FOR MANUFACTURING SAME - The high-strength steel sheet according to the present invention includes a specific chemical composition, a steel structure in which a total area fraction of martensite and bainite in a position of ¼ of a sheet thickness is 92% or more and 100% or less, the balance in a case where the total area fraction is not 100% contains retained austenite, and an area fraction of ferrite in a region extending up to 10 μm in a sheet thickness direction from a surface is 10% or more and 40% or less, in which a tensile strength is 1320 MPa or more, and a Vickers hardness in a position of 15 μm in the sheet thickness direction from the surface satisfies a specified formula. | 2021-10-07 |
20210310095 | HIGH-STRENGTH STEEL SHEET AND METHOD FOR MANUFACTURING THE SAME - There is provided a high-strength steel sheet in which content amounts of a specific steel composition are limited and manufacturing conditions are optimized and that has a steel structure that contains ferrite and a harder phase and in which ferrite accounts for 30% to 70% in terms of area ratio, the harder phase contains bainitic ferrite, tempered martensite, martensite (including 0%), and retained austenite (including 0%), the maximum grain diameter of ferrite d | 2021-10-07 |
20210310096 | METHOD FOR MANUFACTURING A GRAIN-ORIENTED ELECTRICAL STEEL SHEET - Provided is a method for manufacturing a grain-oriented electrical steel sheet. The method comprises: hot rolling a slab to obtain a hot rolled sheet; subjecting the hot rolled sheet to hot band annealing as necessary; subjecting the hot rolled sheet to cold rolling; subjecting the cold rolled sheet to decarburization annealing; applying an annealing separator having MgO as a main component onto a surface of the decarburization annealed sheet and subjecting the decarburization annealed sheet to final annealing to form the forsterite film; and applying an insulating coating treatment liquid onto the final annealed sheet and subjecting the final annealed sheet to flattening annealing to form a tension-applying insulating coating. A difference in total tensions between one and opposite surfaces of the sheet is less than 0.5 MPa. A difference in tensions between the forsterite films in one and opposite surfaces of the sheet is 0.5 MPa or more. | 2021-10-07 |
20210310097 | AMORPHOUS ALLOY RIBBON, PRODUCTION METHOD THEREFOR, AND AMORPHOUS ALLOY RIBBON PIECE - A method of producing an amorphous alloy ribbon having a composition of Fe | 2021-10-07 |
20210310098 | Method for Recovering Gold, Silver and Platinum Metals from Components of a Fuel Cell Stack or of an Electrolyzer - A method for recovering gold, silver, and/or platinum from components of a fuel cell stack of a fuel cell or electrolyzer includes treating the components with an aqueous electrolyte solution and with at least one gaseous oxidant in the fuel cell or the electrolyzer in an oxidation step. In a reduction step, the components are treated with a flow of an aqueous electrolyte solution and with at least one gaseous reductant in the fuel cell or the electrolyzer. A device by which the method can be carried out has a reservoir for the electrolyte solution, a line connected to an outlet opening of the reservoir, the line having a pump, an anode inlet connection connected to an anode inlet, and a cathode inlet connection connected to a cathode inlet. An oxidant-introducer introduces a gaseous oxidant into the line. A reductant-introducer introduces a gaseous reductant and/or inert gas into the line. | 2021-10-07 |
20210310099 | METHOD FOR PRODUCING THERMALLY PROCESSED MATERIAL - Method for producing thermally processed material ( | 2021-10-07 |
20210310100 | PROCESS FOR METALLURGY AND SEPARATING RARE EARTH CONCENTRATE USING COMBINATION METHOD - The present invention provides a process for metallurgy and separating a rare earth concentrate using a combination method, the process including: treating the rare earth concentrate containing bastnaesite by using a method including roasting under an atmosphere, leaching with hydrochloric acids, and roasting with a sulfuric acid, wherein stepping acid leaching with low-concentration hydrochloric acids is controlled during the leaching with the hydrochloric acids so as to obtain a rare earth solution with a high concentration (150-250 g/L REO), such that a leaching rate of Ce reaches 60% or more, and the content of F | 2021-10-07 |
20210310101 | METHOD AND APPARATUS FOR SYNCHRONOUSLY MELTING AND PREPARING ALLOY - An apparatus for synchronously melting and preparing alloy, the alloy to be added is made into wire in advance, and the wire feeding speed required for the preparation of the alloy with a specific composition is calculated according to the flow rate of raw molten aluminum in the launder. In the continuous ingot casting process, the wire is continuously and stably fed into the launder of the raw molten aluminum at the wire feeding speed, and the alloy preparation is formed in real time, which is able to avoid specific gravity segregation caused by the long-term standing of melt, and realize the preparation of gradient materials while significantly improving the alloying efficiency. The present disclosure also relates to a method for synchronously melting and preparing alloy. | 2021-10-07 |
20210310102 | ALUMINUM ALLOY MATERIAL AND METHOD FOR PRODUCING ALUMINUM ALLOY MATERIAL - An aluminum alloy material has a composition containing 3% by mass or more and 10% by mass or less of Fe and the balance of Al and incidental impurities, and a structure including a matrix and a compound. The matrix is composed mainly of Al, the compound contains Al and Fe, and a relative density is 85% or more. In any cross section, the matrix has an average crystal grain size of 1,100 nm or less, and the compound has an average major-axis length of 100 nm or less. | 2021-10-07 |
20210310103 | Pd ALLOY, Pd ALLOY MATERIAL AND PROBE PIN FOR ELECTRIC AND ELECTRONIC DEVICES, AND METHODS FOR MANUFACTURING THE SAME - An object of the present invention is to provide a Pd alloy, a Pd alloy material, and a probe pin for electric and electronic devices in which specific resistance, hardness, and processability are balanced at a higher level than before, and methods for manufacturing the same. In order to achieve this object, the Pd alloy for electric and electronic devices according to the present invention having a composition comprising 50.1 mass % or more and 55.5 mass % or less of Pd, 6.3 mass % or more and 16.1 mass % or less of Ag, 30.0 mass % or more and 38.0 mass % or less of Cu, and 0.5 mass % or more and 2.0 mass % or less of In is adopted. | 2021-10-07 |
20210310104 | HIGH STRENGTH FASTENER STOCK OF WROUGHT TITANIUM ALLOY AND METHOD OF MANUFACTURING THE SAME - This invention generally relates to the field of nonferrous metallurgy, namely to titanium alloy materials with specified mechanical properties for manufacturing the aircraft fasteners. A stock for high strength fastener is manufactured from wrought titanium alloy containing, in weight percentages, 5.5 to 6.5 Al, 3.0 to 4.5 V, 1.0 to 2.0 Mo, 0.3 to 1.5 Fe, 0.3 to 1.5 Cr, 0.05 to 0.5 Zr, 0.15 to 0.3 O, 0.05 max. N, 0.08 max. C, 0.25 max. Si, balance titanium and inevitable impurities, having the value of aluminum structural equivalent [Al]eq in the range of 7.5 to 9.5, and the value of molybdenum structural equivalent [Mo]eq in the range of 6.0 to 8.5, where the equivalents are defined by the following equations: [Al]eq=[Al]+[O]×10+[Zr]/6; [Mo]eq=[Mo]+[V]/1.5+[Cr]×1.25+[Fe]×2.5. A manufacturing method for a stock for high strength fastener includes melting of titanium alloy ingot, production of forged billed from ingot at beta and/or alpha-beta phase field temperatures, hot rolling at a heating temperature of beta and/or alpha-beta phase field to produce a round stock, subsequent annealing of a rolled stock at a temperature of 550° C. to 705° C. (1022° F. to 1300° F.) for at least 0.5 hour followed by drawing to produce a wire with diameter up to 10 mm (0.394 inches) and subsequent annealing at a temperature of 550° C. to 705° C. (1022° F. to 1300° F.) for at least 0.5 hour. A technical result is production of a titanium alloy stock for high strength fastener having high ultimate tensile strength and double shear strength while maintaining a high level of plastic properties in the annealed condition. | 2021-10-07 |
20210310105 | TI- AND NB-ADDED FERRITIC STAINLESS STEEL EXCELLENT IN LOW-TEMPERATURE TOUGHNESS OF WELDS - A Ti, Nb-added ferritic stainless steel with excellent low-temperature toughness of weld zone according to an embodiment of present disclosure includes, in percent (%) by weight of the entire composition, C: 0.004 to 0.015%, N: 0.004 to 0.015%, Si: 0.01 to 0.7%, Mn: 0.01 to 0.7%, P: 0.0001 to 0.04%, S: 0.0001 to 0.005%, Cr: 10 to 30%, Al: 0.005 to 0.04%, Ti: 0.1 to 0.5%, Nb: 0.1 to 0.6%, Ca: 0.0001 to 0.003%, the remainder of iron (Fe) and other inevitable impurities, satisfies the following equation (1), and Al—Ca—Ti—Mg—O-based oxide and Ti—Nb—C—N carbonitride containing the oxide have an average diameter of 3 to 10 μm and a distribution density of 4/mm | 2021-10-07 |
20210310106 | LINER ALLOY, STEEL ELEMENT AND METHOD - Disclosed is a liner alloy and a steel element with a liner alloy element. The liner alloy comprises from 0.5 to 3 wt. % of C, from 10 to 30 wt. % of Cr, less than 2 wt. % of B, less than 4 wt. % of Ti, less than 4 wt. % of Nb, less than 1 wt. % of | 2021-10-07 |
20210310107 | SYSTEMS AND METHODS FOR NON-CONTACT TENSIONING OF A METAL STRIP - Systems and methods of non-contact tensioning of a metal strip during metal processing include passing the metal strip adjacent a magnetic rotor. The magnetic rotor is spaced apart from the metal strip by a first distance. The systems and methods also include tensioning the metal strip through the magnetic rotor by rotating the magnetic rotor. Rotating the magnetic rotor induces a magnetic field into the metal strip such that the metal strip is tensioned in an upstream direction or a downstream direction. In other aspects, rotating the magnetic rotor induces a magnetic field into the metal strip such that a force normal to a surface of the metal strip is applied to the metal strip. | 2021-10-07 |
20210310108 | ALUMINUM-COPPER-LITHIUM ALLOY HAVING IMPROVED COMPRESSIVE STRENGTH AND IMPROVED TOUGHNESS - The invention relates to a product based on an aluminium alloy comprising, as percentages by weight, 4.0 to 4.6% by weight of Cu, 0.7 to 1.2% by weight of Li, 0.5 to 0.65% by weight of Mg, 0.10 to 0.20% by weight of Zr, 0.15 to 0.30% by weight of Ag, 0.25 to 0.45% by weight of Zn, 0.05 to 0.35% by weight of Mn, at most 0.20% by weight of Fe+Si, at least one element selected from Cr, Sc, Hf, V and Ti, the amount of said element, if selected, being from 0.05 to 0.3% by weight for Cr and for Sc, 0.05 to 0.5% by weight for Hf and for V and 0.01 to 0.15% by weight for Ti, the other elements being at most 0.05% by weight each and 0.15% by weight in total, the remainder being aluminium. The invention also relates to a method for obtaining such a product and to the use thereof as an aircraft structural element. | 2021-10-07 |
20210310109 | METHOD OF PRODUCING HOT-DIP METAL COATED STEEL STRIP AND CONTINUOUS HOT-DIP METAL COATING LINE - Provided is a method of producing a hot-dip metal coated steel strip with which a hot-dip metal coated steel strip of high quality can be produced by sufficiently suppressing edge overcoating. The method comprises spraying gas from a pair of gas wiping nozzles | 2021-10-07 |
20210310110 | COVETIC MATERIALS - This disclosure provides a graded composition including at least a first, second, and third material property zone each having a crystallographic configuration distinct from other zones. In some implementations, the graded composition has a first material in the first material property zone including a metal, the first material composed of metallic bonds between metal atoms present in the first material property zone; a second material that at least partially overlaps the first material in the first material property zone including carbon, the second material composed of covalent bonds between the carbon in the second material and the metal in the first material; and, a third material that at least partially overlaps the second material property zone including carbon, the third material composed of covalent bonds between the carbon of the third material. Each crystallographic configuration may include a cubic crystallographic lattice, a hexagonal lattice, a face or body-centered cubic lattice. | 2021-10-07 |
20210310111 | Process for Producing Tinned Copper Wires - Provided is a process for producing a tinned copper wire. The process comprises subjecting a copper wire sequentially to activation treatment, a first hot tinning treatment, a first cooling, a second hot tinning treatment, and a second cooling to obtain a tinned copper wire. The first hot tinning treatment is carried out at a first temperature and the second hot tinning treatment is carried out at a second temperature. The first temperature is higher than the second temperature. The first temperature is at least 38° C. higher than the melting point of tin. The second temperature is at least 8° C. higher than the melting point of tin. | 2021-10-07 |
20210310112 | PART COATED WITH A NON-HYDROGENATED AMORPHOUS CARBON COATING ON AN UNDERCOAT COMPRISING CHROMIUM, CARBON AND SILICON - Disclosed is a part comprising a metal substrate, a non-hydrogenated amorphous ta-C or aC carbon coating that coats the substrate, and an undercoat which is based on chromium (Cr), carbon (C) and silicon (Si) and is disposed between the metal substrate and the amorphous carbon coating and to which the amorphous carbon coating is applied, characterized in that the undercoat included, at its interface with the amorphous carbon coating, a ratio of silicon in atomic percent to chromium in atomic percent (Si/Cr) of 0.3 to 0.60, and a ratio of carbon in atomic percent to silicon in atomic percent (C/Si) of 2.5 to 3.5. | 2021-10-07 |
20210310113 | MULTILAYER FILM, AND AG ALLOY SPUTTERING TARGET - A multilayer film includes: an Ag alloy film; and a transparent dielectric film laminated on both surfaces of the Ag alloy film, and in the Ag alloy film, at least one of Sn or Ge is contained in a range of 0.5 atom % to 8.0 atom % in total, a total content of Na, K, Ba, and Te is 50 ppm by mass or less, a carbon content is 50 ppm by mass or less, and a remainder contains Ag and unavoidable impurities. | 2021-10-07 |
20210310114 | SPUTTERING TARGET, MAGNETIC FILM, AND PERPENDICULAR MAGNETIC RECORDING MEDIUM - Provided is a sputtering target, the sputtering target containing 0.05 at % or more of Bi and having a total content of metal oxides of from 10 vol % to 60 vol %, the balance containing at least Co and Pt. | 2021-10-07 |
20210310115 | ASYNCHRONOUS CONVERSION OF METALS TO METAL CERAMICS - The disclosed invention includes articles having advantageous ceramic layers with a ceramic/metal intermediate layer that diminishes towards a pure metal core. Such articles have substantial use in unconventional, harsh environments. | 2021-10-07 |
20210310116 | ASYNCHRONOUS CONVERSION OF METALS TO METAL CERAMICS - The disclosed invention includes articles having advantageous ceramic layers with a ceramic/metal intermediate layer that diminishes towards a pure metal core. Such articles have substantial use in unconventional, harsh environments. | 2021-10-07 |
20210310117 | METHODS AND SYSTEMS FOR PRODUCING STRUCTURED CARBON MATERIALS IN A MICROGRAVITY ENVIRONMENT - The present disclosure relates to methods and systems for producing structured carbon materials in a microgravity environment. A benefit of the methods and systems disclosed herein can include producing structured carbon materials having fewer defects and reducing excess carbon dioxide in an atmosphere by converting carbon dioxide from an ambient gas into a structured carbon material. | 2021-10-07 |
20210310118 | VAPOR PHASE GROWTH METHOD - Provided is a vapor phase growth method according to an embodiment including loading a first substrate into a reaction chamber, generating a first mixed gas by mixing an indium containing gas, an aluminum containing gas, and a nitrogen compound containing gas, and forming a first indium aluminum nitride film on the first substrate by supplying the first mixed gas into the reaction chamber, the first substrate being rotated at a first rotation speed of 300 rpm or more. | 2021-10-07 |
20210310119 | FILM FORMING METHOD - A film forming method for forming a film by heating a mist in a film-forming unit, the method including steps of: atomizing a raw-material solution in an atomizer to generate a mist; conveying the mist with a carrier gas from the atomizer to the film-forming unit through a conveyor that connects the atomizer and the film-forming unit; and heating the mist to form a film on a substrate in the film-forming unit. In this method, a flow rate of the carrier gas and a temperature of the carrier gas are controlled to satisfy 72021-10-07 | |
20210310120 | DEVICE AND METHOD FOR CONTROLLING THE CEILING TEMPERATURE OF A CVD REACTOR - A CVD reactor may include a susceptor, process chamber and heat dissipation body. In the CVD reactor, one or more layers can be deposited on one or more substrates. The susceptor is heated by a heating device. Heat is transported from the susceptor, through a process chamber towards the process chamber ceiling, through the process chamber ceiling, and from the process chamber ceiling through a gap space to the heat dissipation body. The temperature of the process chamber ceiling is measured at at least two different azimuth angle positions about a central axis of the process chamber. The radial distance of the respective measurement points or zones from the central axis of the process chamber may be equal to one another. The at least two temperature measurement values are used to produce an average value or a difference value. | 2021-10-07 |
20210310121 | SiO2 THIN FILM PRODUCED BY ATOMIC LAYER DEPOSITION AT ROOM TEMPERATURE - A method for atomic layer deposition for the deposition of silicon oxide on a substrate, performed at room temperature, involving at least three precursors, being silicon tetrachloride, water and one Lewis base agent, being in various instances ammonia. The process comprises the steps of exposing on the substrate during an exposure time (a) the one Lewis base agent, (b) the silicon tetrachloride, and (c) the water. The process is remarkable in that at least one step of purge with nitrogen gas is performed after each of the steps (a), (b) and (c) during a purge time. Additionally, a film of silicon oxide which is remarkable in that it comprises a low level of chlorine contaminant and a significant degree of porosity with pores, the pores being in various instances micropores, mesopores or nanopores. | 2021-10-07 |
20210310122 | METHOD OF FORMING HOLES FROM BOTH SIDES OF SUBSTRATE - Methods and apparatus for forming holes through a substrate are provided herein. In some embodiments, a method of forming holes in a substrate for use in a process chamber includes: partially forming the plurality of holes in a substrate using a first drill to form a plurality of rough holes through the substrate from a first side of the substrate to an opposite second side of the substrate; positioning the substrate between a second drill and a third drill; using the second drill to finish the plurality of rough holes from the first side of the substrate to a first location at least halfway along the length of each hole of the plurality of rough holes; and using the third drill to finish the plurality of rough holes from the second side of the substrate to at least the first location along the length of each hole of the plurality of rough holes. | 2021-10-07 |
20210310123 | FLUSH FIXTURE FOR SHOWERHEAD - The present disclosure pertains to embodiments of a flush fixture for flushing a showerhead assembly. The flush fixture includes two distinct cavities, an inner cavity and an outer cavity surrounding the inner cavity and not fluidly connected to the inner cavity. When the flush fixture is mounted to a showerhead, inner apertures are in fluid connection with the inner cavity and one or more exhaust holes are in fluid connection with the outer cavity. Separately accessing the inner apertures and the one or more exhaust holes allows the showerhead to be properly flushed. | 2021-10-07 |
20210310124 | COATING BY ALD FOR SUPPRESSING METALLIC WHISKERS - A deposition method includes depositing on a surface of a substrate a stack by an ALD (atomic layer deposition). Also provided is an ALD reactor for carrying out the method and products obtained using the deposition method. | 2021-10-07 |
20210310125 | MULTI-PORT GAS INJECTION SYSTEM AND REACTOR SYSTEM INCLUDING SAME - A gas injection system, a reactor system including the gas injection system, and methods of using the gas injection system and reactor system are disclosed. The gas injection system can be used in gas-phase reactor systems to independently monitor and control gas flow rates in a plurality of channels of a gas injection system coupled to a reaction chamber. | 2021-10-07 |
20210310126 | METAL-CLAD POLYMER FILMS AND ELECTRONIC DEVICES - In a first aspect, a metal-clad polymer film includes a polymer film adhered to a first metal layer. The root-mean-square roughness (S | 2021-10-07 |
20210310127 | Palladium Plating Solution And Plating Method - The purpose of the present invention is to provide a palladium plating solution and a plating method for improving a bath stability of a palladium plating, without decreasing a deposition property of the palladium plating. A palladium plating solution for improving a bath stability, without decreasing a deposition property, comprising: an aqueous palladium compound; one or more complexing agent containing a compound having at least an ethylenediamine or a propylenediamine skeleton; a formic acid or a formate; and a sulfur compound, wherein the palladium plating solution is having two or more sulfide groups in a molecule of the sulfur compound. | 2021-10-07 |
20210310128 | NON-CHROMATIC CONVERSION COATING SYSTEM AND METHOD - A system and method for coating a foil mesh with a no-chrome conversion coating is provided, wherein the system includes a solution tank, wherein the solution tank defines a tank cavity for containing a conversion coating solution, wherein the conversion coating solution comprises at least one of 5% butyl benzotriazole sodium salt and 7% alodine 5200. The system further includes a reel/roller system configured to cause the foil mesh to be disposed within the conversion coating solution for a predetermine period of time. | 2021-10-07 |
20210310129 | ZnAlMg-Coated Metal Sheet with Improved Flexibility and Corresponding Manufacturing Process - A process for the manufacture of a pre-painted sheet. The process includes supplying a steel substrate, depositing a metallic coating on at least one face by hot-dipping of the substrate in a bath including 4.4% to 5.25% by weight aluminum and 0.3% to 0.56% by weight magnesium. The rest of the bath includes exclusively zinc, unavoidable impurities resulting from the process and optionally one or more additional elements including Si, Ti, Ca, Mn, La, Ce and Bi. The content by weight of each additional element in the metallic coating is less than 0.3% and the presence of nickel is excluded. The process further includes solidifying the metallic coating, surface preparation of the metallic coating and painting of the metallic coating. The present invention further provides a pre-painted sheet. | 2021-10-07 |
20210310130 | HARD COATING AND HARD-COATING-COVERED MEMBER - A hard coating includes a three kinds of layers that are alternately laminated. The three kinds of layers consist of a single composition layer and two kinds of nanolayer-alternated layers. The single composition layer is constituted by one of an A composition (nitride of AlCrSiα), a B composition (nitride of CrBSiβ) and a C composition (nitride of AlCr(SiC)γ). The two kinds of nanolayer-alternated layers include nanolayers which are alternately laminated and which are constituted by two of three combinations consisting of a combination of the A composition and B composition, a combination of the A composition and C composition and a combination of the B composition and C composition. The single composition layer has a thickness of 0.5-1000 nm. Each of the nanolayers constituting the two kinds of nanolayer-alternated layers has a thickness of 0.5-500 nm, and each of the two kinds of nanolayer-alternated layers has a thickness of 1-1000 nm. | 2021-10-07 |
20210310131 | PROCESS FOR SURFACE TREATMENT OF ALUMINUM OR ALUMINUM ALLOYS BY AN ALKALINE CHEMICAL BATH - A process for surface treatment of semi-finished aluminum products is provided. The process includes preparing an aqueous solution of sodium hydroxide (NaOH) and dissolved metallic aluminum, kept in suspension by adding complexing agents including gluconate and sorbitol, and placing a semi-finished aluminum product in contact with the aqueous solution, maintaining temperature of the aqueous solution within a predetermined range. | 2021-10-07 |
20210310132 | AUTOMATED CORROSION MONITORING AND CONTROL SYSTEM FOR MOLTEN SALT EQUIPMENT - The invention provides an in situ method for protecting material exposed to molten salt, the method having the steps of supplying metal in a first nonreactive state to the molten salt to create a mixture; measuring a redox state of the mixture; and transforming the metal to a second reactive state when the redox state indicates corrosion of the material is about to occur. Also provided is a system for preventing corrosion of structural alloys in molten salt environments, the system having a vessel defining a void containing the molten salt; a voltammetry sensor inserted into the molten salt; a first cathode inserted into the molten salt; and a first anode inserted into the molten salt, whereby the cathode and anode are in electrical communication with an electrical power source. | 2021-10-07 |
20210310133 | INTEGRATION CENTER AND APPLICATION FOR ANTI-CORROSION MODULES AND INSTALLATION METHOD FOR ANTI-CORROSIVE PROTECTION OF METALLIC SURFACES - Integration center and application for anti-corrosion modules and installation method for anti-corrosive protection of metallic surfaces consisting of an integration center working with an application for real-time management of an anti-corrosive protection of a metallic surface through anti-corrosion modules, an integration center, a geolocation tool, a motherboard with dedicated processor, WIFI adapters, Bluetooth, Ethernet ports, camera interface plus sensors for measuring temperature. | 2021-10-07 |
20210310134 | A PROCESS AND APPARATUS FOR THE PRODUCTION OF HYDROGEN - A process and apparatus for the production of hydrogen There is provided a process for the production of hydrogen, the process comprising: electrolysing water in an electrolytic cell to produce hydrogen gas and oxygen gas, the electrolytic cell having a first outlet for hydrogen gas; passing the hydrogen gas from the first outlet of the electrolytic cell to a reaction chamber, the reaction chamber comprising a first inlet for receiving the hydrogen gas from the electrolytic cell and a second outlet for hydrogen gas passing out of the reaction chamber, the reaction chamber containing one or more pieces of a metal or an alloy thereof at least partially submerged in an alkali solution, wherein the first inlet is arranged so that the hydrogen gas bubbles through the alkali solution; passing the hydrogen gas from the second outlet to a gas-cleaning chamber, the gas-cleaning chamber comprising a second inlet for receiving hydrogen gas from the reaction chamber and a third outlet for hydrogen gas passing out of the cleaning chamber, the gas-cleaning chamber containing an aqueous solution, wherein the second inlet is arranged so that the hydrogen gas bubbles through the aqueous solution; and recovering hydrogen gas from the third outlet. | 2021-10-07 |
20210310135 | Reactant Flow Channels For Electrolyzer Applications - An electrolyzer or unitized regenerative fuel cell has a flow field with at least one channel, wherein the cross-sectional area of the channel varies along at least a portion of the channel length. In some embodiments the channel width decreases along at least a portion of the length of the channel according to a natural exponential function. The use of this type of improved flow field channel can improve performance and efficiency of operation of the electrolyzer device. | 2021-10-07 |
20210310136 | MODULAR ELECTROLYZER UNIT TO GENERATE GASEOUS HYDROGEN AT HIGH PRESSURE AND WITH HIGH PURITY - The present invention relates to the field of generating gaseous hydrogen at high pressures and with high purity via electrolysis of water by means of an electrolyzer unit ( | 2021-10-07 |