41st week of 2020 patent applcation highlights part 9 |
Patent application number | Title | Published |
20200315882 | ASSISTIVE MOBILITY DEVICE - An assistive mobility device comprising a seat and knee pad, the knee pad arranged to lift a person in a kneeling position into said seat and stabilize said person in said seat, maintaining supportive contact with the person's legs. The seat and knee pad each have an independent rotational tilt adjustment and can be raised and lowered together. | 2020-10-08 |
20200315883 | Wheelchair Having An Adjustable Base - A wheelchair comprises a base assembly and a tilt assembly supported on the base assembly. The base assembly has a wheelbase and a wheel track. Each of the wheelbase and wheel track is independently adjustable. The tilt assembly is unchanged when either the wheelbase or wheel track is adjusted. | 2020-10-08 |
20200315884 | LEG REST RELEASE MECHANISM AND WHEELCHAIR COMPRISING THE SAME - The present disclosure relates to a leg rest release mechanism ( | 2020-10-08 |
20200315885 | Devices and Methods to Help Prevent Decubitus Ulcers - This invention can help a person in bed to avoid decubitus ulcers. This device has a flexible body support structure (such as a sheet or blanket) which is automatically moved from a first configuration which is flat to a second configuration which enfolds and/or wraps around a person's body. The device turns a person from lying on their first side to lying on their opposite side by: enfolding the person in the support structure; rotating or pivoting the support structure; and then releasing the person by unfolding the support structure. | 2020-10-08 |
20200315886 | PRONE-TO-SUPINE TRANSFER MATTRESS - A mattress includes an inflatable pair of first panels connected to each other and defining a first air pocket therebetween; and an inflatable pair of second panels connected to each other and defining a second air pocket therebetween, wherein the pair of first panels and the pair of second panels are operatively connected to each other defining an inflatable tube containing a space to accommodate a user between the pair of first panels and the pair of second panels, and wherein the inflatable tube is rotatable upon inflation of the pair of first panels and the pair of second panels and rotation of the tube. | 2020-10-08 |
20200315887 | Patient Lifting Assembly - A patient lifting assembly includes a first housing that is coupled to a vertical support surface to be positioned adjacent to a user's head when the user is lying in a bed. A first cable is retracted or extended outwardly from the first housing. A first handle is coupled to the first cable and the first handle can be gripped by a user to urge the user toward the head of the bed. A second housing is coupled to a vertical support surface to be positioned adjacent to a user's feet when the user is lying in the bed. A second cable is retracted or extended outwardly from the second housing. A second handle is coupled to the second cable and the second handle can be gripped by a user to urge the user into an upright, seated position. | 2020-10-08 |
20200315888 | PORTABLE FRAME - A portable frame apparatus and associated methods of use are disclosed. The apparatus includes a frame. The frame includes a first support member, a second support member, and at least one connecting member. The connecting member is configured to be coupled to the first support member at a first end of the connecting member and to the second support member at a second end of the connecting member. The first support member, the second support member and the connecting member form a rigid structure that provides support to a user of the portable frame apparatus. | 2020-10-08 |
20200315889 | INFANT WARMERS HAVING INTEGRAL BACKUP WARMING BLANKET - A warming device configured to warm an infant. The warming device includes a base that supports the infant and an overhead portion that includes an enclosure. An arm is coupled to the base and to the overhead portion. The arm supports the overhead portion above the base. A heating element is operated to generate heat to warm the infant. The overhead portion includes the heating element. A portion of the heat is dissipated into the overhead portion as a waste heat. A warming blanket has a stored state and a deployed state. In the stored state, the warming blanket is at least partially inside the overhead portion. In the deployed state, the warming blanket is outside the overhead portion. The warming blanket is designed to store the waste heat when the warming blanket is in the stored state and to warm the infant when in the deployed state. | 2020-10-08 |
20200315890 | THERMOTHERAPY DEVICE - A patient bed assembly unit as well as to a thermotherapy device for newborns includes a bed frame and a drawer. The bed frame has a drawer guide configured to make possible a drawer movement from a central pushed-in position in the bed frame along a first pull-out direction and in a second pull-out direction, which direction is opposite the first pull-out direction, into a pulled-out position of the drawer. A drawer-centering device acts on the drawer to move it into the central pushed-in position. The drawer can be removed from the guide. A drawer anti-tilt device is provided, which transmits a torque acting on the drawer directly to a bed frame and prevents the downward tilting of the drawer relative to the bed frame about an axis extending at right angles to the pull-out directions. | 2020-10-08 |
20200315891 | Medical Technology Station and Method of Use - The invention includes a medical technology station and a method for using the medical technology cart. The station can be a portable cart that can be movable, such as rollable, and has a computer system. Attached to the cart is a housing that communicates with the computer system. Insertable in the housing is a cassette system that includes a series of drawers. The drawers are openable and preferably closeable on command from a user. The drawers have a readable unique drawer identifier that is readable by sensors in the cassette. The cassette also preferably includes proximity sensors, while the drawers contain a target for the proximity sensors. In use, an operator, with proper credentials, can, though the computer system, identify a drawer to be opened by the computer system. The cassette and drawers can be removed from the housing and transported to another location for filling of the drawers with medications or other supplies. | 2020-10-08 |
20200315892 | MODULAR MULTI-ARTICULATED PATEINT SUPPORT SYSTEM - A surgical table for supporting a patient during a surgical procedure and including a patient support structure, a first support structure, and a second support structure. The patient support structure is configured to support the patient during the surgical procedure and may be operably coupled at a first end to the first support structure and at a second end to the second support structure. The first support structure includes a first column and a first displacement apparatus operably coupling the first column to the first end of the patient support structure. | 2020-10-08 |
20200315893 | AERODYNAMIC RAIL COVERS - The present invention relates to an aerodynamic rail cover for an operating room with laminar airflow. In order to provide measures to improve the provision of a laminar airflow in an operating zone, an aerodynamic rail cover ( | 2020-10-08 |
20200315894 | DRESSING WITH TARGETED LOW-INTENSITY VIBRATION - Vibrational dressing systems, vibrational dressing devices, and methods for placing the same are disclosed. Vibrational dressing systems and vibrational dressing devices include a first portion and a second portion. The first portion may be contoured to a target treatment location of a subject. The second portion may be coupled to the first portion and the second portion may include a plurality of vibrational devices and a control system. Each vibrational device may vibrate the target treatment location and each vibrational device may be positioned within the second portion to correspond with a particular location on a body of the subject within the target treatment location when the first portion is coupled to the body of the subject. The control system may selectively activate one or more of the plurality of vibrational devices. | 2020-10-08 |
20200315895 | VIRTUAL SCENE INTERACTIVE REHABILITATION TRAINING ROBOT BASED ON LOWER LIMB CONNECTING ROD MODEL AND FORCE SENSE INFORMATION AND CONTROL METHOD THEREOF - A virtual scene interactive rehabilitation training robot based on a lower limb connecting rod model and force sense information and a control method thereof are disclosed. The thigh, calf and foot of a leg of a human body are equated to a three-connecting rod series-connected mechanical arm. A human body leg gravity compensation model is constructed. The leg posture of a patient is detected by Kinect. An interaction force between a limb of the patient and a rehabilitation robot is detected by a force sensor on the rehabilitation robot. Then, a progressive rehabilitation training method is designed for the model. According to a set weight reduction ratio, the motion of the rehabilitation robot is controlled by judging plantar force data. | 2020-10-08 |
20200315896 | UPPER ARM MODULE OF WEARABLE MUSCULAR STRENGTH ASSISTING APPARATUS AND WEARABLE MUSCULAR STRENGTH ASSISTING APPARATUS INCLUDING SAME - An upper arm module of a wearable muscular strength assisting apparatus includes: a base part fixedly connected to a wearer's body; an upper arm part being configured such that a first end thereof is coupled to the base part to be rotatable about a fixed point, and being coupled to the wearer's upper arm to apply a rotational torque thereto; a first link configured such that a first end thereof is rotatably coupled to the base part at a point of application; a second link extending on a plane on which the upper arm part extends, and being rotatably coupled to a second end of the first link at a first point; a third link coupled to the second link at a second point to guide movement of the second point; and an elastic body generating an elastic force by deformation. | 2020-10-08 |
20200315897 | WEARABLE APPARATUS FOR ASSISTING MUSCULAR STRENGTH - A wearable apparatus for assisting muscular strength includes a back support, and a connection chain having a first end portion coupled to the back support to be rotatable upward or downward. The connection chain extends from the back of the wearer to a side thereof and includes a plurality of rotary elements arranged abreast laterally, each rotary element being rotatably coupled to an adjacent rotary element laterally. The wearable apparatus further includes an upper arm module that extends in a direction in which an upper arm of the wearer extends, one end portion of the upper arm module coupled to a second end portion of the connection chain to be rotatable upward or downward with respect to the one end portion. The upper arm module generates a rotational force for rotating the upper arm of the wearer upward or downward. | 2020-10-08 |
20200315898 | UPPER ARM MODULE OF WEARABLE MUSCULAR STRENGTH ASSISTING APPARATUS AND WEARABLE MUSCULAR STRENGTH ASSISTING APPARATUS INCLUDING SAME - An upper arm module of a wearable muscular strength assisting apparatus is provided. The upper arm module includes a base part configured to be connected to a wearer's body, and an upper arm part having a first end thereof coupled to the base part to be rotatable about a fixed point. The upper arm part is coupled to the wearer's upper arm to apply a torque thereto. The upper arm module further includes an elastic body having a first end thereof fixedly coupled to the upper arm part and generating an elastic force by deformation. In particular, the upper arm module also includes a first link having a first end thereof rotatably coupled to the base part at a point of application, and a second link rotatably coupled to the second end of the first link at a first point. | 2020-10-08 |
20200315899 | ACTUATOR-EQUIPPED KNEE ANKLE FOOT ORTHOSIS - The present invention provides an actuator-equipped knee ankle foot orthosis in which a control device calculates a thigh phase angle based on an angle-related signal detected by a thigh orientation detecting means at one sampling point, applies the thigh phase angle at that sampling point to an assisting force control data, which is stored in the control device in advance and indicates the relationship between the thigh phase angle and a size of the assisting force to be imparted to a lower leg-side brace, to obtain the size of the assisting force to be imparted to the lower leg-side brace at that sampling point, and executes operational control for an actuator unit such that the assisting force having the size is output. | 2020-10-08 |
20200315900 | ANKLE-LESS WALKING ASSISTANT APPARATUS AND METHOD FOR CONTROLLING THE SAME - An ankle-less walking assistant apparatus includes: a body supporting the back of a wearer; left and right hip joint-drivers extending from both sides of the body; left and right thigh links having first ends connected to the left and right hip joint-drivers, respectively; left and right knee-drivers connected to second ends of the left and right thigh links, respectively; left and right calf links having first ends connected to the left and right knee-drivers, respectively; and ground-contact feet fixed to second ends of the left and right calf links, respectively. | 2020-10-08 |
20200315901 | COLLAPSIBLE WHEELED WALKER WITH STABILITY ENHANCING BRACKET APPARATUS AND METHOD - The disclosure demonstrates a collapsible wheeled walker having two side frames supported above a walking surface with attached wheel assemblies. The side frames are interconnected by an X-folder apparatus. The X-folder apparatus has first and second elongate elements rotatably coupled to each other with the bottom ends of the elements rotatably attached to the bottoms of the side frames, and the top ends of the elements having perpendicular support elements that in the deployed open position, engage support brackets formed on the inner sides of the side frames. The support brackets have protrusions extending from bracket support surfaces to engage complementary apertures formed in the perpendicular support elements to provide stability to the wheeled walker. | 2020-10-08 |
20200315902 | PROGRESSIVE MOBILITY AID DEVICE - Disclosed herein are novel embodiments of progressive mobility aid devices. Such progressive mobility aid devices are designed to progress through a variety of configurations to accommodate the use of the progressive mobility aid device in a safe and secure manner as the user of the progressive mobility aid device traverses a variety of surfaces and terrain such as traversing irregular surfaces including sidewalks and stone-based surfaces; loose surfaces and terrain including gravel and sand; soft surfaces including wet ground and carpeted surfaces; and variable gradient surfaces including stairs and inclining or declining surfaces and terrain. The progressive mobility aid devices accommodate such uses with an articulating design that provides for front legs of the progressive mobility aid device to be pivotably adjusted with respect to the rear legs of the progressive mobility aid device, and with wheel assemblies that are selectively deployable and retractable. | 2020-10-08 |
20200315903 | GAZE STABILIZATION SYSTEM AND METHOD - A system is disclosed that allows a practitioner to rotate a human subject's head in three-dimensional space using a robotic arm with a head mount attached to one end, while the subject is focused on a visual target. | 2020-10-08 |
20200315904 | EXFOLIATING HEAD WITH ROLLING ELEMENTS - The invention provides a body care device ( | 2020-10-08 |
20200315905 | Compression Device Especially for Preventing Deep Vein Thrombosis - A compression device particularly suited for DVT prophylaxis includes a disposable wrap and a re-usable controller removably mounted on the wrap to apply a tensioning force to the wrap when it is encircling the limb of a patient. The wrap includes an RF chip with a unique identifier and the controller includes an RF sensor and processor to authenticate the wrap before commencing a compression cycle. A kiosk is provided for storing a plurality of wraps for use by patients and a plurality of controllers to be used with any of the wraps. The processor of each controller can control an electric motor in the controller to tighten and loosen the wrap according to a three-stage DVT prophylaxis protocol that produces an optimum blood flow velocity. An accelerometer and software/firmware in the controller can also measure and summarize patient activity while wearing the device. | 2020-10-08 |
20200315906 | Compression Device Especially for Preventing Deep Vein Thrombosis - A compression device particularly suited for DVT prophylaxis includes a disposable wrap and a re-usable controller removably mounted on the wrap to apply a tensioning force to the wrap when it is encircling the limb of a patient. The wrap includes an RF chip with a unique identifier and the controller includes an RF sensor and processor to authenticate the wrap before commencing a compression cycle. A kiosk is provided for storing a plurality of wraps for use by patients and a plurality of controllers to be used with any of the wraps. The processor of each controller can control an electric motor in the controller to tighten and loosen the wrap according to a compression protocol between a pre-tension compression force and maximum compression force. The amount of movement of the wrap changes as the patient's physiology changes while maintaining the pre-tension and maximum compression forces. | 2020-10-08 |
20200315907 | Phototherapy Body Roller - The present invention discloses a phototherapy body roller, which comprises a rotatable outer casing having at least one transparent portion. The outer casing is hollow, and a light board and a power supply device for supplying power to the light board are installed therein, and the light board is mounted on the light housing, and the light emitting tubes are facing the transparent portion of the outer casing. A balancing device is also mounted in the outer casing, and the light housing is fixedly mounted with the balancing device. The phototherapy body roller can perform LED light therapy while using as a body roller for self-exercise, stretching, fascia and relieve fatigue and relax muscle groups. With a balancing device, the light source is always facing the upper part of the phototherapy body roller, which saves energy and does not cause light pollution, and is environmentally friendly. | 2020-10-08 |
20200315908 | WEARABLE MASSAGER - The present disclosure generally relates to a massaging device such as a wearable massager. The wearable massager may include a moveable cover, a first magnet, a second magnet, a first shell, a second shell, a printed circuit board, a motor, and a battery. The wearable massager may be operated to provide a massaging effect to a wearer of the massager at a desired body part location at a desired time. | 2020-10-08 |
20200315910 | FATIGUE REDUCING DEVICE - A fatigue reducing device according to an embodiment includes, as an example, a determinator that determines whether an occupant sitting on a seat of a vehicle is driving the vehicle, and a controller that controls a vibration device provided in the seat to apply vibration stimulation at a first frequency causing muscular tension to a second muscle serving that is an antagonist muscle to a first muscle that is a massage target in a case where the determinator has determined that the occupant is driving the vehicle. | 2020-10-08 |
20200315911 | SOUND THERAPY SYSTEMS AND METHODS FOR RECALIBRATING THE BODY'S ELECTROMAGNETIC FIELD - A sound treatment system includes an audio system for transmitting tones of predetermined frequencies through a plurality of outputs. A sound transmitting device is electrically connectable to one or more of the outputs, and includes a speaker for transmitting the tones received. The speaker is adjacent to crystal which is vibrationally responsive to the tones. A method of using the system includes generating tonal segments of predetermined duration, modulating the frequencies, and compiling these into an audio program. One or more sound transmitting devices are placed on desired locations of the body, and their inputs connected to corresponding outputs of the audio system. The generating step includes compiling selected predetermined frequencies into an audio program to generate the tonal segments, as well as modulating tones of one or more desired frequencies to generate the tonal segments. | 2020-10-08 |
20200315912 | GRAPHENE NANO-STEAM GENERATOR AND BEAUTY INSTRUMENT THEREOF - A graphene nano-steam generator and a beauty instrument are provided. The graphene nano-steam generator includes a coarse steam channel, a nano-steam channel and a high-voltage power supply device. The coarse steam channel is connected to a coarse steam manufacturing device and the nano-steam channel. The coarse steam channel is provided with a steam sieving device, and an end of the coarse steam channel is provided with a first electrode and a second electrode. The high-voltage power supply device is coupled to the first electrode and the second electrode. The high-voltage power supply device supplies high-voltage electricity to the first electrode and the second electrode, and forms a high-voltage arc discharge between the first electrode and the second electrode, thus the coarse steam molecular group flowing through is ionized by the high-voltage arc to generate a large amount of active nano-scale steam to be flowed out from the nano-steam channel. | 2020-10-08 |
20200315913 | INFUSION BAG OF MIDAZOLAM FOR INTRAVENOUS USE - The invention relates to an infusion container comprising a sterile, ready-to-use, stable aqueous solution of Midazolam or a pharmaceutically acceptable salt thereof, suitable for direct intravenous infusion to a patient in need thereof. The invention also relates to a novel infusion container having plurality of ports that is suitable for delivering or receiving a sterile fluid, such as the said stable aqueous solution of Midazolam or a pharmaceutically acceptable salt thereof. | 2020-10-08 |
20200315914 | MEDICAL VESSELS AND SYSTEMS WITH PIERCING MEMBERS AND UNLOCK MECHANISMS - The present invention relates, in some embodiments thereof, to devices, systems and methods for establishing a fluid passageway between vessels. In some embodiments, the invention provides a system for the engagement and establishment of fluid passageway between vessels, the system comprises a first and second vessels configured to be coupled to each other wherein at least one of the first and second vessels comprises a piercing member disposed within the vessel in a retracted position wherein the piercing member confined within/adjacent a port or aperture of the vessel, the piercing member configured to pierce through a cover/seal of the vessel at about the time of or following the engagement between the first and second vessels, thereby establishing a fluid transfer between the vessels. | 2020-10-08 |
20200315915 | MULTI CHAMBER FLEXIBLE BAG AND METHODS OF USING SAME - A method of preparing a pharmaceutical product in a single multiple chamber flexible bag. A pharmaceutical product is introduced in a liquid state into a first chamber of the flexible bag through a first port. The pharmaceutical product is lyophilized within the first chamber of the flexible bag to provide a lyophilized pharmaceutical product. The flexible bag has a second chamber and the first chamber and the second chamber are separated by a breakable seal. The second chamber further includes a reconstituting solution for reconstituting the lyophilized pharmaceutical product in the first chamber. A user may apply pressure to the flexible bag to break the seal and mix the lyophilized pharmaceutical product and the reconstituting solution to order to administer the pharmaceutical product to a patient. | 2020-10-08 |
20200315916 | MEDICAL VESSELS WITH DYNAMIC FLUID TRANSFER LOCK MECHANISM - The present invention relates, in some embodiments thereof, to devices, systems and methods for establishing a fluid passageway between vessels. In some embodiments, the invention provides a system that comprises a first vessel; a second vessel configured to be coupled to the first vessel; and a plunger locking mechanism disposed on the first vessel and configured to lock a plunger thereof and prevent the plunger from expelling content of the first vessel prior to an engagement with the second vessel, wherein the first and/or second vessel(s) comprise(s) an unlock mechanism configured to unlock the lock mechanism of the first vessel, and wherein at the time of or following the engagement between the first vessel and the second vessel, the unlock mechanism unlocks the lock mechanism of the plunger, allowing movement thereof and thereby a fluid transfer from the first vessel to the second vessel. | 2020-10-08 |
20200315917 | SYSTEM, APPARATUS, AND METHOD FOR EXTENDING THE USEFUL LIFE OF MEDICINE - An apparatus to preserve a first fluid of a medicine vial is provided. The apparatus may include a vial coupling member comprising a housing and a flexible membrane. The housing and the flexible membrane form a vial coupling member cavity within the vial coupling member. The apparatus may also include a first fluid pathway forming a first lumen that is in fluid communication with the vial coupling member cavity. The apparatus may further include a second fluid pathway forming a second lumen that is in fluid communication with the vial coupling member cavity. When the flexible membrane engages the medicine vial, the flexible membrane forms a sealed environment over a medicine vial septum. When the flexible membrane engages the medicine vial, the flexible membrane permits the first lumen and the second lumen to establish fluid communication with an interior space of the medicine vial. | 2020-10-08 |
20200315918 | MEDICAL VESSELS WITH VALVES AND VALVE LOCK-UNLOCK MECHANISMS - The present invention relates, in some embodiments thereof, to devices, systems and methods for establishing a fluid passageway between vessels. In some embodiments, the invention provides a system for the engagement and establishment of fluid passageway between vessels, the system comprises a first vessel comprising a valve; and a second vessel configured to be coupled to the first vessel; wherein the second vessel comprises a valve unlock mechanism configured to unlock/open the valve, and wherein at about the time of or following the engagement between the first and second vessels, the valve unlock mechanism unlocks/opens the valve, allowing a fluid transfer between the vessels. | 2020-10-08 |
20200315919 | Dry Powder Inhalation Drug Products Exhibiting Moisture Control Properties and Methods of Administering the Same - A drug product comprising:
| 2020-10-08 |
20200315920 | MICROLAYER COEXTRUSION TO CREATE A TIME-RELEASE DRUG SUBSTANCE DELIVERY PRODUCT - The present disclosure relates to medical devices containing time-release drug substance, and more particularly, to medical tubing, catheters, stents, cables (including fiber optic cables), pills, capsules, sheaths, threads, clamps, sutures, and endotracheal devices. The invention also generally relates to a method for extruding multiple laminated flow streams using microlayer coextrusion to create these various time-release drug delivery products. | 2020-10-08 |
20200315921 | Syringe Plunger with Hinged Flange - A plunger for movably mounting within a cavity or barrel of a syringe. The plunger includes a contact face having a flange movably mounted thereto, wherein the flange is movable between an open configuration wherein an opening is formed between the flange and a portion of the plunger, the opening configured for engagement with an IV hook or other engagement member, and a closed configuration wherein the upper surfaces of the contact face and the flange are generally planar with one another. | 2020-10-08 |
20200315922 | TALKING PACIFIER APPARATUS - A talking pacifier that will serve as an interpreter and an advocate for the vocally challenged, namely infants. The device contains a microprocessor coupled to a speaker for providing short musings that will appear to be delivered by the user of the device. In a preferred embodiment an activation button releases a baby's musings on everything from potty talk to politics. | 2020-10-08 |
20200315923 | DESINFECTANT BONE AND DENTAL FILLER MATERIALS COMPRISING LIPOSOMES - Bone or dental filler materials include liposomes, which give them disinfectant properties. These filler materials are used, in particular, for filling dental pulp or a bone defect. | 2020-10-08 |
20200315924 | INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE - The present disclosure provides an inorganic dental filler including a surface treated with at least one silane. Exemplary silanes described in the present disclosure for the surface treatment of the inorganic filler include silanes of Formula I and/or Formula II: (R | 2020-10-08 |
20200315925 | DENTAL COMPOSITE MATERIAL AND MILL BLANKS CONSISTING OF SAID COMPOSITE MATERIAL - A polymerisable dental composite material comprising
| 2020-10-08 |
20200315926 | CUSTOM FORMULATION SYSTEMS - Custom formulation systems include a user input device and a dispenser having a cabinet, a bead assembly, a fluid formulation assembly, and a mixing area. The bead assembly dispenses a plurality of beads containing a first cosmetic formulation, and is one of a plurality of bead assemblies located within the cabinet. The plurality of bead assemblies has a vertically organized configuration. The fluid formulation assembly is configured to dispense a second cosmetic formulation in flowable fluid form, and is one of a plurality of fluid formulation assemblies located within the cabinet. The mixing area is located within the cabinet and configured to receive at least one bead from the bead assembly and the second cosmetic formulation in flowable fluid form from the fluid formulation assembly. The vertically organized bead assemblies, the fluid formulation assemblies, and the mixing area are positioned adjacent to a first side of the cabinet. | 2020-10-08 |
20200315927 | SOLID COSMETIC COMPOSITION FOR EYE MAKE-UP INCLUDING FIBER - The present invention relates to a stick formulation cosmetic composition for eye make-up comprising a fiber and a hectorite-based oil thickener, and a stick formulation cosmetic product manufactured using the composition. A cosmetic composition according to an aspect allows a fiber to attach to eyebrows, providing an excellent effect of making the eyebrows look full, and also has excellent sustainability and waterproof properties. | 2020-10-08 |
20200315928 | MULTISTAGE COLORED POLYMER PARTICLE AND SKIN CARE FORMULATIONS COMPRISING SAME - A multistage colored polymer particle is provided, having a core comprising polymerized units of a monoethylenically unsaturated carboxylic acid core monomer and a non-ionic ethylenically unsaturated core monomer; an inner shell comprising polymerized units of a non-ionic ethylenically unsaturated inner shell monomer; a monoethylenically unsaturated carboxylic acid inner shell monomer; optionally, an aliphatic inner shell monomer; and, optionally, a first polymerizable dye monomer; an outer shell comprising polymerized units of a non-ionic ethylenically unsaturated outer shell monomer; a monoethylenically unsaturated non-carboxylic acid outer shell monomer; optionally, a second polymerizable dye monomer; and, optionally, an aliphatic outer shell monomer; wherein the core, when dry, contains at least one void; and wherein the multistage colored polymer particle comprises polymerized units of polymerizable dye monomer. Skin care formulations comprising multistage colored polymer particles and methods of using same are also provided. | 2020-10-08 |
20200315929 | OIL-IN-WATER TYPE EMULSION SOLID COSMETIC - An oil-in-water type emulsion solid cosmetic that causes “adhesion” similar to that of a water-in-oil type emulsion solid cosmetic including wax, while having freshness and a moisturizing effect of an oil-in-water type emulsion substance. An oil-in-water type emulsion solid cosmetic contains (A) at least one hydrophilic thickening agent selected from the group consisting of gellan gum, agar, and copolymers including 2-acrylamide-2-methyl propane sulfonic acid, (B) a higher alcohol, (C) a surfactant, (D) water, and (E) an oil component, wherein the ratio between the blending amount of the (A) hydrophilic thickening agent and the total blending amount of the (B) higher alcohol and the (C) surfactant falls within the range of 3:1-1:9. | 2020-10-08 |
20200315930 | COMPOSITION FOR TOPICAL SKIN CARE - The present invention relates to a novel topical composition for treatment of the skin. The composition is a microemulsion that comprises curcumin or a curcumin derivative. The composition is able to penetrate into skin cells where it induces the production of adenosine triphosphate (ATP) and promotes the formation of new skin cells. The formation of new skin cells smoothes the skin and alleviates lines and wrinkles. The topical composition can be applied to the skin of a person daily. The invention also relates to the use of the novel topical composition for delaying skin aging. In another aspect, the invention relates to the use of the novel composition for reducing or preventing hair loss and/or inducing the growth of new hair. | 2020-10-08 |
20200315931 | Encapsulation - The invention describes a core shell microcapsule wherein the capsule shell is hydrolysable. The capsule is made from a water phase with initiator and emulsifier, and from one or more oil phases having a first multifunctional (meth)acrylate monomer having greater than one ester group on average in the monomer and having a hydrophilicity index of less than 20; a second multifunctional (meth)acrylate monomer, the second multifunctional (meth)acrylate comprising a hydrophilic multifunctional polar monomer having a hydrophilicity index of at least 20 and said second multifunctional polar monomer comprising 50% or less of the capsule shell along with an acidic (meth)acrylate monomer or at least one oil soluble or dispersible simple acid, the acidic (meth)acrylate monomer having one or more groups which are selected from carboxy and sulfonic groups, and optionally from 0 to 50% by weight of the shell comprises in addition an aliphatic polyester comprising an oligomer, polymer or co-polymer of one or more of lactic acid, caprolactone, or glycolic acid, the aliphatic polyester having two or more of acrylate or methacrylate groups. | 2020-10-08 |
20200315932 | STABLE, REVERSIBLE, COLORED PHOTOCHROMIC ADDITIVES AND METHODS OF MAKING THE SAME - A stable and consistent reversible coloured photochromic additive changes colour from original buff to desired colour shade between pink to blue when exposed to sunlight and restores to original colour in the absence of the sunlight; simultaneously having synergistic SPF value of at least 3. The additive comprises titanium dioxide, psuedoboehmite, iron oxide hydroxide and tungsten oxide. | 2020-10-08 |
20200315933 | USE OF CANNABIDIOL OR CANNABIS EXTRACT IN PREPARATION OF SKIN WHITENING PRODUCTS - The present invention belongs to the field of medicaments and daily chemicals, and relates to use of cannabidiol or an cannabis extract in preparing a skin whitening product. Particularly, the present invention relates to use of any one of (1) to (2) below in preparing a drug or a reagent for inhibiting tyrosinase activity, inhibiting melanin formation or inhibiting melanocyte generation: (1) cannabidiol or a pharmaceutically acceptable salt or ester thereof; and (2) a plant extract containing cannabidiol. The cannabidiol or the cannabis extract can effectively inhibit activity of tyrosinase, and has a good skin whitening effect. | 2020-10-08 |
20200315934 | MONOPHASIC APPEARANCE COSMETIC HAIR COMPOSITION COMPRISING A PARTICULAR NONIONIC SURFACTANT - The present invention relates to a cosmetic composition having a monophasic appearance, comprising at least one particular non-ionic surfactant, water and at least one propellant. The invention also relates to an aerosol device and also to a process for styling keratin fibres using such a composition. | 2020-10-08 |
20200315935 | TOPICALLY APPLICABLE CHEMICAL PEEL COMPOSITION - A topically applicable chemical peel composition for home use having from about 4% to about 13%, by weight, of alpha hydroxy acid, from about 0.1% to about 2.0%, by weight, of salicylic acid, from about 0.1% to about 2.0%, by weight, of phenylethyl resorcinol and balance essentially dermatologically acceptable liquid solvent comprising water and ethanol, the ethanol present from about 10 to about 90 wt %. In addition, a chemical skin peel regime or regimen including topical application onto the skin is also disclosed. | 2020-10-08 |
20200315936 | HAIR STRENGTHENING INGREDIENT AND METHOD FOR STRENGTHENING HAIR - A method for strengthening and repairing keratin fibres including providing a first—and a second crosslinking composition, wherein the first—crosslinking composition comprises an at least bi-functional Brønsted-base and the second—crosslinking composition comprises—an at least bi-functional organic acid, and a cosmetically acceptable carrier; applying the first—as well as the second—crosslinking composition to keratin fibres; and optionally mixing the first—crosslinking composition into a commercially available hair coloring or hair bleaching composition. | 2020-10-08 |
20200315937 | HAIR TREATMENT AGENT COMPRISING SPECIFIC CHELATING AGENTS - The present disclosure relates to a hair treatment agent comprising at least one specific chelating agent, at least one diol and at least one triol. Moreover, the present disclosure relates to the use of the specific chelating agent to remove undesired multivalent metal ions from hair that has previously been treated with relaxing agents containing at least one multivalent metal ion. Furthermore, the present disclosure relates to a method for relaxing keratinic fibers wherein the inventive hair treatment agent is applied after relaxing the hair with a relaxing composition comprising a multivalent metal hydroxide. After the inventive hair treatment agent is applied, the hair is treated with an acidic cleansing composition. Finally, the present disclosure relates to a kit of parts, comprising a hair relaxing composition with a multivalent metal hydroxide, an inventive hair treatment composition and an acidic cleansing composition in separate containers. | 2020-10-08 |
20200315938 | HAIR TREATMENT COMPOSITION - The present invention is in the field of hair treatment compositions; in particular relates to hair treatment compositions for hair volume reduction. Despite the prior art, there still exists the opportunity to increase the conditioning benefits delivered through hair treatment compositions. It is therefore an object of the present invention to provide a hair treatment composition that retains shape and reduces frizz even after exposure to humidity and washing the hair. It has been found that reduced hair frizz and hair shape retention even after exposure to moisture can be obtained by using N-formyl amino acids. | 2020-10-08 |
20200315939 | A TOPICAL COMPOSITION - The present invention relates to a topical composition comprising from 0.001 to 10% by weight a compound of formula (I), i.e. N-cyclopropyl nicotinamide, that provides improved antimicrobial effect through generation of antimicrobial peptides when applied to an external surface of the human body. A combination of compound of formula I and at least one ingredient selected from niacinamide, picolinamide and iso-nicotinamide triggers generation of AMPs in a synergistic way. | 2020-10-08 |
20200315940 | USE OF THIOPHOSPHATE DERIVATIVES AS SKIN DEPIGMENTING AGENTS - The present invention relates to a skin depigmentation composition comprising (i) at least one thiophosphate derivative and (ii) acceptable carriers for topical, oral and/or parenteral administrations to human. The present invention further relates to the cosmetic and medical treatment uses thereof for reducing skin and/or hair pigmentation. | 2020-10-08 |
20200315941 | METHOD OF FACILITATING THE BINDINGS BETWEEN KERATINOCYTES - Provided is a novel peptide and a cosmetic composition for inhibiting a skin-aging or a skin-wrinkle formation including the same. The peptide has activities for facilitating the bindings between keratinocytes; and increasing the expressions of junction proteins significantly. | 2020-10-08 |
20200315942 | METHODS AND KITS OF REMOVING CALCULUS - Methods and kids for removing calculus from a tooth. The method can include applying a component A comprising a hydrogen peroxide or a precursor thereto and a component B the comprising a catalase to the tooth, thereby generating oxygen; and removing at least a part of the calculus from the tooth. | 2020-10-08 |
20200315943 | REMOVAL OF BIOLOGICAL DEPOSITS - Provided herein is a method of at least partly removing a biological deposit, such as a dag, from the skin of an animal. The method includes administering to the biological deposit an effective amount of a composition containing a keratinase, and optionally one or both of a reducing agent and a surfactant. Also provided is a composition for use in the aforementioned method as well as a method of making same. | 2020-10-08 |
20200315944 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ACRYLIC POLYMER AND A FATTY ACID ESTER OF DEXTRIN - The present invention relates to a composition, especially a cosmetic, in particular photoprotective, composition, comprising at least: —one or more particular acrylic polymers —one or more fatty acid esters of dextrin, and —one or more UV-screening agents. | 2020-10-08 |
20200315945 | Actinic Light Curable Dip System - An actinic light curable dip gel comprises an acrylic resin selected from the group consisting of a poly(C | 2020-10-08 |
20200315946 | FRAGRANCE PRODUCT - An anhydrous and alcohol-free slow fragrance diffusive composition (lotion, gel or cream) with longer lasting properties than hydroalcoholic formula fragrance product that contains 50 to 75 percent by weight dimethicone crosspolymer gel, 0.01 to 30 percent by weight fragrance oil and 5 to 40 percent by weight volatile linear silicone fluid. Emollients may be added to moisturize the skin, improve the fragrance rendition and/or increase the miscibility of the fragrance oil in the composition when a high level of dimethicone is used (in case of a lotion for example). Moreover, a preservative and some pigments can be added to the formula to preserve the fragrant product from bacteria contamination and to improve the aesthetics respectively. | 2020-10-08 |
20200315947 | Personal Care Compositions - Disclosed herein are liquid cleansing compositions comprising a foam booster comprising ethoxylated hydrogenated castor oil present in an amount ranging from about 0.5% to about 2% based on the total weight of the composition, castor oil maleate, glycerin, and at least one surfactant, wherein the pH of the composition is less than about 7. The liquid cleansing compositions disclosed herein provide enhanced foam volume and texture. Further disclosed herein are methods of making a liquid cleansing composition. | 2020-10-08 |
20200315948 | EAR-CLEANSING AGENT FOR COMPANION ANIMALS AND METHOD OF MANUFACTURING THE SAME - The present invention relates to an ear-cleansing agent for companion animals and a method of manufacturing the same. More particularly, the present invention relates to an ear-cleansing agent for companion animals, which includes distilled | 2020-10-08 |
20200315949 | COMPOSITIONS AND METHODS FOR HAIR REGROWTH - The disclosure provides compositions and methods for promoting hair growth and reducing hair loss using bioactive extracts of curcumin, | 2020-10-08 |
20200315950 | COMPOSITION FOR MODULATING THE GENES RESPONSIBLE FOR GENERAL SKIN FUNCTIONS, METHOD FOR MODULATING THE EXPRESSION OF GENES RESPONSIBLE FOR GENERAL SKIN FUNCTIONS, AND USE OF A PLANT EXTRACT - The present invention relates to compositions for modulating genes responsible for the general functions of the skin comprising at least one plant extract and at least one cosmetically acceptable vehicle, as well as to a method for modulating the expression of genes responsible for the general functions of the skin, and use of said plant extract in the preparation of a composition for modulating genes responsible for the general functions of the skin. | 2020-10-08 |
20200315951 | SKIN WHITENING COMPOSITION COMPRISING CULTURE OF PSEUDOALTEROMONAS CARRAGEENOVORA OR EXTRACT THEREOF - Disclosed in the specification is a skin whitening composition comprising as an effective ingredient a | 2020-10-08 |
20200315952 | Compositions And Methods For The Maintenance Of Oral Health - The invention provides a probiotic formulation that includes an LDH-deficient | 2020-10-08 |
20200315953 | Method and System for Preventing Sore Throat in Humans - A method and system to prevent sore throat infections in humans includes the administration of an active ingredient to a site on the mucus membranes of the throat of a human that inhibits adherence and promotes desorption of | 2020-10-08 |
20200315954 | Topical Skin Compositions and Devices and Methods for Using Same - The present disclosure provides topical skin formulations including sunscreen compositions and cannabidiol compositions. The present disclosure further provides topical skin formulations including both sunscreen agents and cannabidiol. The sunscreen agents are included in an amount from about 0.01 to 20% by weight. Cannabidiol is included in an amount from about 0.01 to 10% by weight. A method for applying multiple topical skin formulations includes separately storing a sunscreen composition and a cannabidiol composition in a multi-chambered device. The multi-chambered device may be configured to dispense each composition independently of the other or simultaneously in adjustable ratios. | 2020-10-08 |
20200315955 | SUCCINYLCHOLINE PREFILLED SYRINGE, COMPOSITIONS AND METHODS - Pre-filled syringes, pharmaceutical compositions, and kits and methods relating to same allow for emergency administration of one or more drugs from prefilled glass syringes to a patient via a needleless connector. In preferred embodiments, the prefilled glass syringe has a drug volume of at least 5 mL, has a Luer-lock, and has a syringe tip with an internal channel that has a diameter of about 1.7 mm. Such syringes advantageously allow storage of emergency drugs without leaching of plastic materials and degradation, and substantially improve the safety profile where the syringe is attached to an IV line via a needleless connector. | 2020-10-08 |
20200315956 | COMPOSITIONS AND METHODS FOR TREATING INTERVERTEBRAL DISCS - A biocompatible antimicrobial composition effective against microbial biofilms, including in vivo biofilms containing gram-positive bacteria, can be delivered to and used near the spinal column of vertebrates. Once introduced to an area colonized with a bacterial biofilm, particularly an intervertebral disc, the antimicrobial composition weakens the EPS/ECPS macromolecules of the biofilm, which makes the entire biofilm structure susceptible to being dislodged from the affected area or biosorbed. Additionally or alternatively, certain of the subcomponents of the solute component, as well as perhaps the organic liquid(s) of the solvent component, might lyse microbes, particularly gram-positive bacteria, previously protected by the EPS/ECPS macromolecules. Swelling of and around previously impacted intervertebral discs can be reduced or eliminated, often resulting in appreciable reductions in patient pain levels. | 2020-10-08 |
20200315957 | VETERINARY CANNABINOID, MENTHOL AND ANESTHETIC COMPOSITIONS AND METHODS - The present disclosure relates to compositions, including, hydrogel compositions useful as analgesics including cannabinoids, menthol and anesthetic in a composition formulated to be administrable to a non-human animal rectally as a suppository. The menthol component can be a stabilized menthol composition comprising menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid. | 2020-10-08 |
20200315958 | PERSONAL LUBRICANTS COMPRISING LAMBDA-CARRAGEENAN - The present invention includes pourable, non-toxic lubricating compositions containing carrageenan and more precisely λ carrageenan as an anti-viral agent, for protection from Human Papillomavirus (HPV), and methods of using the lubricating compositions as a non-oily, pseudoplastic lubrication product and administering the carrageenan for reducing the propagation of HPV during sexual activity. | 2020-10-08 |
20200315959 | PERSONAL LUBRICANTS COMPRISING LAMBDA-CARRAGEENAN - The present invention includes pourable, non-toxic lubricating compositions containing carrageenan and more precisely λ carrageenan as an anti-viral agent, for protection from Human Papillomavirus (HPV), and methods of using the lubricating compositions as a non-oily, psuedoplastic lubrication product and administering the carrageenan for reducing the propagation of HPV during sexual activity. | 2020-10-08 |
20200315960 | DRUG DELIVERY DEVICE AND METHOD - A biocompatible intravaginal device adapted for the delivery of therapeutic active ingredients (agents) is provided. The device is constructed to be insertable and remain in the vagina for up to a month (28 to 31 days) or more. The device is loaded with the active agents prior to insertion and constructed to continuously release a therapeutically effective amount of the agents during the duration of up to a one month insertion. Preferred agents include contraceptive and anti-infection agents. It is preferred that the agents are non-hormonal. | 2020-10-08 |
20200315961 | MULTILAYER THIN FILM DRUG DELIVERY DEVICE AND METHODS OF MAKING AND USING THE SAME - Multilayer thin film devices that include a bioactive agent for elution to the surrounding tissue upon administration to a subject are provided. The multilayer thin film devices are useful as medical devices, such as ocular devices. Also provided are methods and kits for localized delivery of a bioactive agent to a tissue of a subject, and methods of preparing the subject devices. The multilayer thin film medical device includes a first layer, a bioactive agent and a second layer. The first and the second layers may be porous or non-porous. The devices have a furled structure, suitable for administration to a subject. | 2020-10-08 |
20200315962 | ORAL PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING PARTICULATE FORMULATION COMPRISING COMPOSITION - Provided is an oral pharmaceutical composition characterized by containing a medicinal ingredient (A), a hydrophobic liquid (B), a water-soluble macromolecular substance (C), and an excipient (D), but not containing a surfactant, wherein: the medicinal ingredient (A) is included in the hydrophobic liquid (B); and the hydrophobic liquid (B) is dispersed in a composition including the water-soluble macromolecular substance (C) and the excipient (D). The oral pharmaceutical composition: allows easy dose-adjustment; has excellent dosability and safety; is biologically equivalent to a standard formulation having established profiles regarding efficacy, safety, etc.; and can be easily produced. | 2020-10-08 |
20200315963 | Hydrocortisone Acetate Suppository Formulation For Treatment Of Disease - The present invention relates, in various embodiments, to formulations comprising hydrocortisone and silicon dioxide. In additional embodiments, the invention relates to suppositories comprising hydrocortisone and silicon dioxide. The formulations of the present invention are useful for administration to patients who have gastrointestinal diseases and disorders such as, for example, inflammatory bowel disease. | 2020-10-08 |
20200315964 | NOVEL SEMI-SOLID PREPARATION - The present invention relates to a novel preparation. The present invention has an advantage of enabling bitterness of the raw material medicine to be masked by only the physical shape thereof. The present invention breaks away from general knowledge, and is a concept having never been conceived of thus far and is a novel preparation, which can be widely used in the pharmaceutical industry in the future. | 2020-10-08 |
20200315965 | NANOEMULSION CONCENTRATE FORMULATIONS AND METHODS - The disclosure provides a stable nanoemulsion concentrate suitable for formulation of one or more non-polar active ingredients, for example a cannabinoid, together with methods of making and using the same. | 2020-10-08 |
20200315966 | Liposomal Compounds and Methods of Use Thereof - A composition and method for treating a subject following myocardial infarction are provided. The composition includes a non-PEGylated liposome. The method includes administering a non-PEGylated liposome to a subject in need thereof following myocardial infarction. | 2020-10-08 |
20200315967 | LIPID NANOPARTICLES - The invention features methods and apparatus for producing lipid nanoparticles. Methods of the invention include injecting a lipid solution into an aqueous solution at an automated rate (e.g., a rate controlled by a servo pump). The invention provides methods and apparatus for making lipid nanoparticles possessing a wide range of lipid components and hydrophilic encapsulants, including nucleic acids (e.g., mRNA). Also provided are nanoparticles and compositions thereof made by methods and apparatus of the invention. | 2020-10-08 |
20200315968 | METHOD FOR PRODUCING PHARMACEUTICAL COMPOSITION CONTAINING FINE PARTICLES OF POORLY SOLUBLE DRUG - The present invention provides a method for producing a pharmaceutical composition containing fine particles of a poorly soluble drug, comprising mixing a sugar or a sugar alcohol with a dispersion of nanoparticles of the poorly soluble drug and granulating the obtained mixture. | 2020-10-08 |
20200315969 | PHARMACEUTICAL COMPOSITIONS COMPRISING SAFINAMIDE - The present invention relates to pharmaceutical compositions comprising safinamide and, more particularly, to taste-masked particles comprising said active ingredient or pharmaceutically acceptable salts thereof, oral dosage forms that include said particles and a process for preparing them. | 2020-10-08 |
20200315970 | TABLETS WITH HIGH ACTIVE INGREDIENT CONTENT OF OMEGA-3 FATTY ACID AMINO ACID SALTS - The present invention relates to a tablet comprising one or more omega-3 fatty acid amino acid salt(s), a method for preparing a tablet according to the invention and the use of a tablet according to the invention as a food supplement or as a pharmaceutical product. | 2020-10-08 |
20200315971 | 3D PRINTING METHODS FOR COMPARTMENTED PHARMACEUTICAL DOSAGE FORMS - The present disclosure provides a stable solid pharmaceutical dosage form for oral administration. The dosage form includes a substrate that forms at least one compartment and a drug content loaded into the compartment. The dosage form is so designed that the active pharmaceutical ingredient of the drug content is released in a controlled manner. | 2020-10-08 |
20200315972 | FORMULATIONS OF A COMPOUND AND USES THEREOF - The present disclosure relates to formulations, such as tablets, of FXR agonists and therapeutic uses thereof. The disclosure also relates to methods for obtaining such formulations. | 2020-10-08 |
20200315973 | METHOD FOR PREPARING A PHARMACEUTICAL PRODUCT - A method of preparing a pharmaceutical product comprises the steps of (a) providing a neat active pharmaceutical ingredient (API) complying with at least five of the following parameters determined by using a FT4 powder rheometer: (i) specific basic flow energy of at most 60 mJ/g; (ii) stability index of 0.75 to 1.25; (iii) specific energy of at most 10 mJ/g; (iv) major principle stress at 15 kPa of at most 40; (v) flow function at 15 kPa of at least 1.3; (vi) consolidated bulk density at 15 kPa of at least 0.26 g/mL; (vii) compressibility of at most 47%; and (viii) wall friction angle of at most 40°; (b) dispensing the neat API of step (a) into a bottom part of a pharmaceutical carrier using a vacuum assisted metering and filling device; and (c) encapsulating the bottom part, thereby producing a pharmaceutical product. | 2020-10-08 |
20200315974 | APPLICATION OF PHARMACEUTICAL COMPOSITION IN REGULATION OF FIBROBLAST GROWTH - An application of an oral pharmaceutical composition in manufacturing of a medication for regulating fibroblast growth and treating or preventing organ fibrosis. The pharmaceutical composition comprises a homogeneous mixture of an edible oil, beeswax, and β-sitosterol, wherein the beeswax forms microcrystals, and on the basis of the total weight of the composition, the content of the beeswax is 0.5-50% and the content of β-sitosterol is 0.1%-20%. | 2020-10-08 |
20200315975 | THREE-DIMENSIONAL PRINTED STRUCTURAL SILOXANES HAVING CONTROLLED DRUG RELEASE - According to one embodiment, a core-shell microsphere includes a polyorganosiloxane shell, and a core inside the shell, the core having a carrier and at least one component, where the at least one component is configured to be released post processing. In addition, an average diameter of the polyorganosiloxane shell is in a range of greater than about 1 micron to less than about 100 microns. | 2020-10-08 |
20200315976 | Encapsulation Methods and Compositions - This invention provides methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as a “glue” to cause more than one biological substance to adhere together, or as carriers for biologically active species. Several methods for forming these membranes are provided. Each of these methods utilizes a polymerization system containing water-soluble macromers, species, which are at once polymers and macromolecules capable of further polymerization. The macromers are polymerized using a photoinitiator (such as a dye), optionally a cocatalyst, optionally an accelerator, and radiation in the form of visible or long wavelength UV light. The reaction occurs either by suspension polymerization or by interfacial polymerization. The polymer membrane can be formed directly on the surface of the biological material, or it can be formed on material, which is already encapsulated. | 2020-10-08 |
20200315977 | ENTERIC COATING COMPOSITION, SOLID PREPARATION AND METHOD FOR PRODUCING SOLID PREPARATION - There are provided an enteric coating composition having an excellent film-forming property, being capable of forming a film at a lower temperature than conventional compositions, and/or being capable of avoiding decomposition of a drug due to a high temperature and operational troubles due to or nozzle clogging; and others. More specifically, there are provided an enteric coating composition containing hypromellose acetate succinate having a molar substitution of hydroxypropoxy groups of 0.40 or more, and water; a method for producing a solid preparation including steps of coating a drug-containing core with the enteric coating composition to obtain a coating layer, and drying the coating layer; and a solid preparation containing a drug-containing core, and a coating layer directly or indirectly on the core, the coating layer containing a hypromellose acetate succinate having a molar substitution of hydroxypropoxy groups of 0.40 or more. | 2020-10-08 |
20200315978 | MULTILAYERED PHARMACEUTICALLY ACTIVE COMPOUND-RELEASING MICROPARTICLES IN A LIQUID DOSAGE FORM - A controlled-release multilayer microparticle containing a pharmaceutically active compound, which is intended for oral administration or direct administration in the stomach, which may be done using a liquid pharmaceutical composition containing the microparticle. The microparticle may include: a core that includes the pharmaceutically active compound, which may be pramipexole; a controlled-release intermediate coating layer; and an outmost external protection coating layer surrounding the controlled-release intermediate coating layer. The external protection coating layer may include a mixture of: a hydrophilic gastro-soluble component which is insoluble in aqueous media at a pH of between 6.5 and 7.5; and a hydrophobic and/or insoluble component. Also disclosed are a liquid pharmaceutical composition containing the microparticles, a kit for the preparation of the liquid pharmaceutical composition, a pharmaceutical solid composition reconstitutable as the liquid composition, a process of preparing the liquid composition, and a method for treating disease with the liquid composition. | 2020-10-08 |
20200315979 | METHOD FOR COATING PARTICLES - Methods are provided for coating particles characterised by the addition of a powdered excipient, typically during coating. Typically, the coating method comprises Wurster fluidized bed coating. The method provides for coating particles in a coater comprising a coating processing chamber, wherein the particles comprise an active pharmaceutical ingredient. The coated particles are preferably for use in a method of administering an active pharmaceutical ingredient or for use in a method of treating or preventing a disease or condition. The invention further provides a pharmaceutical composition comprising coated particles obtainable by the method of the invention, preferably as part of a liquid formulation for oral administration. | 2020-10-08 |
20200315980 | Drug Delivery System Comprising Nanocarrier Loaded with Urate Oxidase and Metal-Based Nanoparticle Capable of Degrading Hydrogen Peroxide and Pharmaceutical Composition Comprising the Same - The present disclosure is directed to a drug delivery system in which urate oxidase and metal-based nanoparticles for hydrogen peroxide degradation are loaded in a temperature-sensitive nanocarrier, and a pharmaceutical composition for treating hyperuricemia-related disease comprising the drug delivery system. In the drug delivery system of the present disclosure, urate oxidase and metal-based nanoparticles for hydrogen peroxide degradation are positioned close to each other, thereby effectively removing the toxic substance hydrogen peroxide (H | 2020-10-08 |
20200315981 | COMPOSITIONS AND METHODS FOR NANOPARTICLE-BASED DRUG DELIVERY AND IMAGING - Methods and compositions described herein use polysaccharide nanoparticles (or polysaccharide-coated nano -particles) to retain and deliver unaltered therapeutic agents to sites of disease. The polysaccharide nanoparticles are non-covalently associated with the unaltered therapeutic agent. The polysaccharide is able to retain cargo (drugs, diagnostics, etc.) without chemical modification of the agent. The nanoparticle maintains its association with the agent through non-covalent interactions but releases its agent in response to changes in the microenvironment, e.g., at the site of cancer cells or cancer tissue. | 2020-10-08 |
20200315982 | POLYMERIC BILE ACID ESTER NANOPARTICLES TO INDUCE TOLERANCE - Polymeric bile acid (pBA) nanoparticles and tolerogenic formulation containing polymeric bile acid nanoparticles for oral delivery and induction of antigen-specific tolerance in a subject may include immunosuppressants and/or disease-specific antigen. Oral delivery results in local organ accumulation as well as systemic delivery of the nanoparticles. Early intervention with the nanoparticles induces antigen-specific tolerance and prevents development of autoimmune disorders. Treatment with the nanoparticles results in long-term antigen-specific immune tolerance, even after cessation of treatment, in autoimmune diseases. | 2020-10-08 |