41st week of 2013 patent applcation highlights part 37 |
Patent application number | Title | Published |
20130266953 | AGGREGATION INDUCED EMISSION OF FLUORESCENT BIOPROBES AND METHODS OF USING THE SAME - Provided herein are fluorescent bioprobes comprising fluorogens that exhibit aggregation-induced emission (AIE) labeled on biomolecules. The present subject matter relates to a fluorescent bioprobe comprising one or more fluorogen labeled on chitosan. The present subject matter is also directed to methods of preparing the fluorescent bioprobes, methods of labeling and detecting DNA and/or proteins with the fluorescent bioprobe, and methods of cell imaging including live cell tracking. | 2013-10-10 |
20130266954 | METHOD FOR FORMING A CELL AGGREGATE - A method for forming a cell aggregate in the present invention is a method for forming a cell aggregate by using a culturing vessel and culturing an adhesive cell, wherein the culturing vessel is such that an amino group, a carboxyl group, and/or a hydroxyl group, and a group represented by a general formula of | 2013-10-10 |
20130266955 | EFFERVESCENT COMPOSITIONS AND USES THEREOF - A latent effervescent body comprising a selective agent is disclosed. A method of using the latent effervescent body in a method to selectively enrich a target microorganism is also disclosed. The method comprises providing a sample, a culture medium, and the latent effervescent body. The method further comprises contacting the sample, the culture medium, and the latent effervescent body under conditions to facilitate growth of the target microorganism. The method further comprises releasing the selective agent from the latent effervescent body. Optionally, the method includes detecting a microorganism. | 2013-10-10 |
20130266956 | MICROFLUIDIC DEVICES AND METHODS FOR ASSAYING A FLUID SAMPLE USING THE SAME - Multi-directional microfluidic devices and methods for using the same are provided. Aspects of the present disclosure include microfluidic devices that include a chamber having a separation medium, a first binding medium, and a second binding medium. In addition, the devices include a flow field element configured to subject the chamber to two or more directionally distinct flow fields. Methods of using the devices, as well as systems and kits that include the devices are also provided. The devices, systems and methods find use in a variety of different applications, including diagnostic, research and validation assays. | 2013-10-10 |
20130266957 | HIGHLY FLUORESCENT POLYMER NANOPARTICLE - Fluorescent nanoparticles are provided. The nanoparticles are formed from poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-(1-cyanovinylene-1,4-phenylene)]. Also provided are methods for imaging a target to which the nanoparticles are bound. | 2013-10-10 |
20130266958 | METHOD FOR ACTIVATING HELPER T CELL - The present invention relates to a method for activating helper T cells, which includes the step of activating helper T cells by adding a WT1 peptide to antigen presenting cells, wherein the WT1 peptide has the ability to bind to any MHC class II molecule of an HLA-DRB1* 0101 molecule, an HLA-DRB1* 0401 molecule, an HLA-DRB1* 0403 molecule, an HLA-DRB1* 0406 molecule, an HLA-DRB1* 0803 molecule, an HLA-DRB1* 0901 molecule, an HLA-DRB1* 1101 molecule, an HLA-DRB3* 0202 molecule, an HLA-DRB4* 0101 molecule, an HLA-DPB1* 0201 molecule or an HLA-DPB1* 0301 molecule, and the like. | 2013-10-10 |
20130266959 | PRINCIPLE COMPONENT ANALYSIS (PCA) - BASED ANALYSIS OF DISCONTINUOUS EMISSION SPECTRA IN MULTICHROMATIC FLOW CYTOMETRY - The invention relates to a system for acquiring discontinuous emission spectra data, whereby the data is analyzed by a multivariate statistic model or equivalent model, such as principal component analysis and the use of the system for flow cytometry. | 2013-10-10 |
20130266961 | DIAGNOSIS AND RISK STRATIFICATION BY MEANS OF THE NOVEL MARKER CT-PROADM - The invention relates to a novel diagnostic marker CT-proADM (C-terminal fragment of preproADM, SEQ ID No. 1) for diagnosing and/or stratifying the risk of diseases. Also disclosed is a method for diagnosing and/or stratifying the risk of diseases, particularly cardiovascular diseases, cardiac insufficiency, and infections and/or inflammations of the lungs and respiratory tract. In said method, the CT-proADM (SEQ ID No. 1) marker, or a partial peptide of fragment thereof, or said marker contained in a marker combination (panel, cluster) is determined in a patient who is to be examined. The invention further relates to a diagnostic apparatus as well as a kit for carrying out said method. | 2013-10-10 |
20130266962 | MEANS AND METHODS FOR DIAGNOSING CANCER USING AN ANTIBODY WHICH SPECIFICALLY BINDS TO BRAF V600E - The present invention relates to the field of diagnostic tests and diagnostic tools. Specifically, contemplated is to a method for diagnosing cancer in a sample of a subject suspected to suffer from cancer comprising contacting the sample with an antibody which specifically binds to the epitope characterized by SEQ ID NO 1 on a BRAF polypeptide under conditions which allow for binding of said antibody to the epitope and determining binding of the antibody to the epitope, whereby cancer is diagnosed. Further contemplated are antibodies which specifically bind to the epitope characterized by SEQ ID NO 1 on a BRAF polypeptide and a device or kit comprising such antibodies. | 2013-10-10 |
20130266963 | ASSAY FOR DETECTING NEUTRALIZING AUTOANTIBODIES TO BIOLOGIC THERAPY - The present invention provides assays for detecting and measuring the presence or level of neutralizing and non-neutralizing autoantibodies to biologics such as anti-TNFα drug therapeutics in a sample. The present invention is useful for monitoring the formation of neutralizing and/or non-neutralizing anti-drug antibodies over time while a subject is on biologic therapy. The present invention is also useful for predicting and/or determining the cross-reactivity of neutralizing anti-drug antibodies in a subject's sample with alternative biologic therapies. As such, the present invention provides information for guiding treatment decisions for those subjects receiving therapy with a biologic agent and improves the accuracy of optimizing therapy, reducing toxicity, and/or monitoring the efficacy of therapeutic treatment to biologic therapy. | 2013-10-10 |
20130266964 | METHOD OF DETECTING ENDOTHELIAL PROGENITOR CELLS - A method of detecting endothelial progenitor cells is provided. The method involves contacting a population of cells with a composition comprising a conjugate or complex of the formula A | 2013-10-10 |
20130266965 | Identification of Non-Small Cell Lung Carcinoma (NSCLC) Tumors Expressing PDGFR-ALPHA - The invention discloses a previously unidentified subset of mammalian non-small cell lung carcinomas (NSCLC) in which platelet-derived growth factor receptor alpha (PDGFRα) is expressed and is driving the disease, and provides methods for identifying a mammalian NSCLC tumor that belongs to a subset of NSCLC tumors in which PDGFRα is expressed, and for identifying a NSCLC tumor that is likely to respond to a PDGFRα-inhibiting therapeutic. The invention also provides methods for inhibiting the progression of a mammalian NSCLC tumor in which PDGFRα is expressed, and for determining whether a compound inhibits the progression of a PDGFRα-expressing mammalian NSCLC tumor. | 2013-10-10 |
20130266966 | METHOD OF DETERMINING RISK OF SCOLIOSIS - A method for determining the risk for developing a scoliosis comprising monitoring osteopontin (OPN) expression in a sample from a subject over time; wherein an OPN expression that increases in the subject sample over time is indicative that the subject is at risk for developing a scoliosis. | 2013-10-10 |
20130266967 | FUNCTION HOMOLOGY SCREENING - A method of screening biologically active agent based on the analysis of complex biological responses in culture. Methods for selecting cells and culture conditions for such screens are provided, as well as the identification of an optimized set of discrete parameters to be measured, and the use of biomap analysis for rapid identification and characterization of drug candidates, genetic sequences acting pathways, and the like. A feature of the invention is simultaneous screening of a large number of cellular pathways, and the rapid identification of compounds that cause cellular responses. | 2013-10-10 |
20130266968 | DETECTION OF INFLUENZA VIRUS - The present application describes methods for detecting influenza A and/or influenza B and/or distinguishing between pathogenic and seasonal influenza A subtypes. Many of these preferred formats employ pan-specific antibodies (i.e., that react with all or at least multiple strains within an influenza type) to detect presence of influenza A and/or influenza B and PDZ domains in combination with panspecific antibodies to influenza A to distinguish pathogenic and seasonal influenza A subtypes. | 2013-10-10 |
20130266969 | METHOD OF AND SYSTEM FOR PRINTING IN-WELL CALIBRATION FEATURES - An apparatus and a method are disclosed for printing in-well calibration features onto assay substrates. An apparatus includes a testing substrate; a plurality of capture compound features in a well of the testing substrate; a calibration feature on one of the capture compound features in the well of the testing substrate, where the calibration feature has a known concentration of a compound that is capable of binding to the capture compound; and at least one additional capture compound feature in the same well of the testing substrate, where the at least one additional capture compound feature does not have a calibration feature printed onto the at least one additional capture compound feature. Methods for using the same are disclosed. | 2013-10-10 |
20130266970 | PLASMA BIOMARKER FOR DISTAL METASTASIS IN COLORECTAL CANCER - The present invention proposes secretory gelsolin (pGSN) as a plasma biomarker for evaluating distal metastasis of colorectal cancer. The present invention uses a special amino acid sequence of pGSN to fabricate a pGSN-specific polyclonal antibody. The present invention further uses the pGSN-specific polyclonal antibody to develop a high-specificity ELISA method and an assay kit thereof for evaluating distal metastasis of colorectal cancer. | 2013-10-10 |
20130266971 | POLYSACCHARIDE AND DERIVATIVES THEREOF, SHOWING AFFINITY TO FICOLIN-3, METHOD OF PREPARATION AND USE - The invention relates to bacterial lipopolysaccharide and its components, especially native and chemically modified polysaccharides isolated from | 2013-10-10 |
20130266972 | METHOD OF DETECTING PROTEIN LOSING ENTEROPATHY IN ANIMALS - The present invention provides a method and kit for the detection of Protein Losing Enteropathy (PLE) in animals. The method includes the steps of (a) obtaining a biological sample from an animal to be tested and (b) determining the absence or presence of albumin in the biological sample via a kit comprising an immunoassay utilizing a species-specific anti-albumin antibody. | 2013-10-10 |
20130266973 | IDIOTYPIC ANTIBODIES AND USES THEREOF - The invention provides anti-idiotypic HCMV antibodies as well as methods of using the same. | 2013-10-10 |
20130266974 | METHOD FOR DIAGNOSING HYPERTENSION AS WELL AS CARDIOMYOPATHIES - A method for diagnosis and/or prediction of hypertension and/or cardiovascular end-organ damage is disclosed. The method disclosed comprises the determination of the presence of soluble pro-renin receptor in samples derived from a subject. Furthermore, the use of anti-sPRR antibodies in diagnosis and/or prediction of cardiovascular end-organ damage is encompassed. | 2013-10-10 |
20130266975 | Body Fluid BIN1 as a Marker of Cardiac Health - The present disclosure provides methods involving use of BIN1 protein levels in biological fluid of a subject in evaluating cardiac health of the subject. The method provided herein may be used to predict a risk of a poor outcome in a subject. The methods also find use in evaluating subjects for assessing patients diagnosed with heart failure. These methods are also useful in assessing therapy options and efficacy of treatment in heart failure patients. | 2013-10-10 |
20130266976 | BIOMARKERS ASSOCIATED WITH NEPHROPATHY - Use of urine biomarkers for diagnosing nephropathy, monitoring nephropathy progress, and assessing efficacy of a nephropathy treatment. These urine biomarkers include leukocyte-associated Ig-like receptor-2, alpha-1 acid glycoprotein, their fragments, and combinations thereof. | 2013-10-10 |
20130266977 | METHODS AND SYSTEMS FOR DETECTION OF MICROBES - Provided herein are methods, test units, systems, assays and kits for qualitative and/or quantitative detection of microorganisms or microbes. Some aspects of the invention utilize a test strip comprising a test area and a self-calibrating control area that permits quantitative measurements to be obtained rapidly at the test site. The test strip is ready-to-use and does not require any preparation. The present systems and methods provide valuable tools for sensitive early detection of microbial contamination. | 2013-10-10 |
20130266978 | METHOD AND DEVICE FOR ESTIMATING MOLECULAR PARAMETERS IN A SAMPLE PROCESSED BY MEANS OF CHROMATOGRAPHY - A method for estimating molecular parameters in a sample comprising the following steps: passing the sample through a processing chain including a chromatography step; thereby obtaining a representative signal of molecular parameters as a function of at least one variable of the processing chain; and estimating the molecular parameters using a signal processing device by inverting a direct analytical model of said signal defined as a function of the molecular parameters and technical parameters of the processing chain. Moreover, the processing chain includes a step for multiple measurements of the same product from the chromatography step, the direct analytical model of said signal comprises modelling of this multiple measurement step, and this modelling requires at least one common characteristic of the signals obtained from these multiple measurements. | 2013-10-10 |
20130266979 | LAB-ON-A-CHIP DEVICE, FOR INSTANCE FOR USE OF THE ANALYSIS OF SEMEN - The invention provides a lab-on-a-chip device comprising a micro channel for a fluid, wherein the micro channel comprises a circumferential channel wall, wherein the channel wall comprises a first electrode, a second electrode, and a floating third electrode. The device can be used in a method for the analysis of an analyte fluid comprising flowing the analyte fluid through the channel of the electronic lab-on-a-chip device by measuring an electric signal between the first and the second electrode, especially measuring the electrical impedance between the first electrode and the second electrode. This may be used for instance for the analyses of mammalian semen. | 2013-10-10 |
20130266980 | SYSTEM, DEVICE, METHOD AND COMPUTER ACCESSIBLE MEDIUM FOR IMAGING LARGE AREAS WITH MICROSCOPIC RESOLUTION - Exemplary systems, method and non-transitory computer-accessible medium can be provided for generating an image of at least one tissue that can be subdivided into a plurality of strips. Using such exemplary systems, method and computer-accessible medium, it is possible to scan, using an optical arrangement to generate first information, a first portion of the tissue(s) along a first one of the strips while the tissue(s) can be mechanically moved in a first direction. Move the one tissue(s), by a distance equal to or less than a width of the first portion, in a second direction approximately perpendicular to the first direction. Use the optical arrangement to generate second information, a second portion of the tissue(s) along a second one of the strips while the tissue(s) can be mechanically moved in a third direction, which can be approximately opposite to the first direction. Then the image can be generated based on the first information and the second information. | 2013-10-10 |
20130266981 | EXPRESSION OF CLASS 2 MANNOSIDASE AND CLASS III MANNOSIDASE IN LOWER EUKARYOTIC CELLS - A method for producing human-like glycoproteins by expressing a Class 2 α-mannosidase having a substrate specificity for Manα1,3 and Manα1,6 glycosidic linkages in a lower eukaryote is disclosed. Hydrolysis of these linkages on oligosaccharides produces substrates for further N-glycan processing in the secretory pathway. | 2013-10-10 |
20130266982 | METHOD OF PRODUCING BIOLOGICALLY ACTIVE VITAMIN K DEPENDENT PROTEINS BY RECOMBINANT METHODS - The invention relates to commercially viable methods for producing biologically active vitamin K dependent proteins, particularly Factor IX. Factor IX is produced at a level of at least about 15 mg/L and is at least 25% biologically active. The method relies upon co-expression of one or more of paired basic amino acid converting enzyme (PACE), vitamin K dependent epoxide reductase (VKOR) and vitamin K dependent γ-glutamyl carboxylase (VKGC) at a preferred ratio so that the vitamin K dependent protein is efficiently produced and processed by a recombinant cell. | 2013-10-10 |
20130266983 | Creation of super-stable ColE1 plasmids by duplication of SL1-4 sequence and point mutations. - Super-stable plasmids useful to improve yields of large-scale recombinant gene expression. | 2013-10-10 |
20130266984 | FILAMENTOUS FUNGI WITH INACTIVATED PROTEASE GENES FOR ALTERED PROTEIN PRODUCTION - The invention relates to a filamentous fungal cell (e.g., | 2013-10-10 |
20130266985 | Process for Cell Culturing by Continuous Perfusion - The invention relates to a process for the culturing of cells by continuous perfusion culturing of a cell culture comprising cell culture medium and cells, wherein cell culture medium is added to the cell culture, the cell culture is circulated over a filter module comprising hollow fibers resulting in an outflow of liquid having a lower cell density than the cell culture and the flow within the filter module is an alternating tangential flow. Preferably, culture medium is added at a particular perfusion rate and/or biomass is removed form the culture at least once. The method is especially suitable for the culturing of aggregating cells. The invention also relates to such a process wherein a biological substance, preferably an antibody, is produced by the cells, which biological substance may be further purified in downstream processing. | 2013-10-10 |
20130266986 | PROCEDURE FOR THE PRODUCTION OF TIACUMICIN B - The present invention relates to a process for the production of tiacumicin B which comprises fermentation of a micro-organism of the species | 2013-10-10 |
20130266987 | METHOD AND AGENTS FOR PRODUCING N-ACETYLNEURAMINIC ACID (NEUNAC) - The invention relates to an isolated nucleic acid molecule comprising at least one promoter that is active in fungal cells of the | 2013-10-10 |
20130266988 | METHOD FOR GENE AMPLIFICATION - The present invention provides a double-stranded DNA constructed specifically for high speed gene amplification, a method for gene amplification and a method for synthesizing protein. The gene amplification system of the present invention used a site-specific recombinase such as Cre-lox system and target sequence thereof to efficiently induce a type of replication referred to as a double rolling-circle replication (DRCR). Amplification unit, whose structure is shown in FIG. | 2013-10-10 |
20130266989 | METHODS TO IMPROVE VECTOR EXPRESSION AND GENETIC STABILITY - The present invention relates to methods of developing gene inserts that are more compatible with the host vectors by modifying a protein sequence to lessen potential interference with vector propagation while ensuring that the protein is expressed and processed efficiently and maintains desired structural features, and designing a gene with a nucleotide sequence that resembles the base composition of the host vector genome. | 2013-10-10 |
20130266990 | STEPWISE ENZYMATIC HYDROLYSIS PROCESS FOR CONVERTING CELLULOSE TO GLUCOSE - A method for the production of alcohol and other bioproducts hemicelluloses extracted from biomass prior to thermal conversion of the biomass to energy. The process can be integrated with the host plant process to minimize the energy loss from extracting hemicelluloses. Also disclosed is a Stepwise enzymatic break down of cellulose fibers from a pulping operation which is performed with the redeployment of equipment and vessels contained within typical existing pulp and paper manufacturing mills. The preferred feedstock is highly delignified pulp from acid or alkaline pulping process or from bleaching stage. | 2013-10-10 |
20130266991 | METHOD FOR PRODUCING CONCENTRATED AQUEOUS SUGAR SOLUTION - A method produces a concentrated aqueous sugar solution using a cellulose-containing biomass as a raw material, including:
| 2013-10-10 |
20130266992 | COMPOSITION FOR INCREASING SACCHARIFICATION EFFICIENCY OF BIOMASS, METHOD FOR INCREASING SACCHARIFICATION EFFICIENCY OF BIOMASS AND METHOD FOR PREPARING BIOETHANOL DERIVED FROM BIOMASS ON A LARGE SCALE USING CHAPERONE PROTEIN - The present invention relates to a novel method for increasing saccharification efficiency by adding chaperone protein during saccharification process, more precisely a composition for increasing saccharification efficiency of biomass containing cellulose using peroxiredoxin (Prx) protein and a method for increasing glucose yield by using the same. The conventional saccharification process has the disadvantage of decreasing cellulase activity, suggesting that the high priced saccharogenic enzyme has to be continuously supplied since the saccharogenic enzyme is losing its activity continuously by reducing sugar through the whole saccharification process. Therefore, to increase saccharification efficiency, the present invention provides a method characterized by increasing saccharification efficiency by preventing cellulase from losing its activity throughout the whole saccharification process by using chaperone protein, particularly Prx protein herein, together with cellulase. The method of the present invention, therefore, can overcome the disadvantage of the conventional saccharification process. | 2013-10-10 |
20130266993 | Method for Producing Carboxylic Acid Using Methanol-Assimilating Bacterium - A method for producing a carboxylic acid by a fermentation process which comprises culturing a methanol-assimilating bacterium capable of producing the carboxylic acid in a liquid medium containing methanol and a counter ion to produce and accumulate the carboxylic acid in the medium, further comprising the feeding of a substance comprising methanol and a counter ion to the medium by fed-batch culturing to maintain the total ionic strength within the fermentation medium at or below a certain level. | 2013-10-10 |
20130266994 | TRANSAMINASE POLYPEPTIDES - The present disclosure provides engineered transaminase enzymes having improved properties as compared to a naturally occurring wild-type transaminase enzyme. Also provided are polynucleotides encoding the engineered transaminase enzymes, host cells capable of expressing the engineered transaminase enzymes, and methods of using the engineered transaminase enzymes to synthesize a variety of chiral compounds. | 2013-10-10 |
20130266995 | METHOD FOR PRODUCING D-TYPE LACTIC ACID - The present invention provides a method for producing D-type lactic acid, by a sugar fermentation of sugar. In accordance with the method of the invention, lactic acid produced during the fermentation reaction is selectively absorbed and detached using an active carbon stick. The method does not require steps, such as, lactate concentration and electrodialytic water splitting that are required during the lactic acid fermentation process. According to the invention, D-type lactic acid can be produced in a high purity and with a high yield. Further, the time and cost associated with the separation process can be reduced in a great extent, thereby offering advantageous effects from a commercial perspective. | 2013-10-10 |
20130266996 | METHOD AND APPARATUS FOR PRODUCING LACTIC ACID - The present invention provides an apparatus and a method for producing lactic acid, wherein only lactic acid is selectively absorbed and separated from fermentation liquor using a lactic acid absorption resin and wherein a neutralizing agent is not used. The present invention does not include a neutralizing process and a process of converting lactate to lactic acid. The method of the present invention comprises the steps of: adding and mixing a culture medium, microorganism and sugar in a fermenter; passing a fermentation liquor through a microorganism filtration unit to remove microorganism through a cross-flow filtration; and selectively absorbing and separating lactic acid from filtered liquid using a lactic acid absorption resin. Accordingly, the separation and purification process of lactic acid from a fermentation liquor for polymerization is simplified. The manufacturing cost is thus reduced. The apparatus of the invention includes a fermenter for lactic acid fermentation; a filtration unit for removing a microorganism present in a fermentation liquor; and a lactic acid absorption resin for selectively absorbing lactic acid from a filtered liquid. | 2013-10-10 |
20130266997 | INTEGRATED PROCESSES FOR REFINING SYNGAS AND BIOCONVERSION TO OXYGENATED ORGANIC COMPOUND - Integrated processes are provided for syngas refining and bioconversion of syngas to oxygenated organic compound. In the integrated processes ammonia contained in the syngas is recovered and used as a source of nitrogen and water for the fermentation. The integrated processes first remove tars from syngas by scrubbing using a first aqueous medium under conditions that ammonium bicarbonate is unstable. With tars removed, contact between the syngas and a second aqueous medium enables ammonia and carbon dioxide to be removed from the syngas without undue removal of components adverse to the fermentation, processing or oxygenated product such as benzene, toluene, xylene, ethylene, acetylene, and hydrogen cyanide. At least a portion of the second aqueous medium is supplied as a source of water and ammonia for the fermentation. | 2013-10-10 |
20130266998 | NOVEL OXIDOREDUCTASES FOR ENANTIOSELECTIVE REACTIONS - Described herein are compositions and methods for generating oxidoreductases for enantioselective reactions. Described herein are compositions and methods for generating neomorphic (R)-2-hydroxyacid dehydrogenases capable of enzymatically converting a 1-carboxy-2-ketoacid to a 1-carboxy-(R)-2-hydroxyacid, or the reverse reaction. Illustrative examples include (a) (R)-2-hydroxyadipate dehydrogenase and uses thereof for converting 2-oxoadipate to (R)-2-hydroxyadipate, or the reverse reaction; and (b) (R)-2-hydroxyglutarate dehydrogenase and uses thereof for converting 2-oxoglutarate to (R)-2-hydroxyglutarate, or the reverse reaction. Also described herein are compositions and methods for generating non-natural microbial organisms to enzymatically convert 2-oxoadipate to (E)-2-hexenedioate or adipate, or to enzymatically convert 2-oxoglutarate to (E)-2-pentenedioate or glutarate, or the respective reverse reactions. | 2013-10-10 |
20130266999 | CORYNEFORM BACTERIUM TRANSFORMANT AND PROCESS FOR PRODUCING PHENOL USING THE SAME - Provided is a phenol-producing transformant constructed by transferring a gene which encodes an enzyme having 4-hydroxybenzoate decarboxylase activity into | 2013-10-10 |
20130267000 | CORYNEFORM BACTERIUM TRANSFORMANT AND PROCESS FOR PRODUCING PHENOL USING THE SAME - Provided is a phenol-producing transformant constructed by transferring a gene which encodes an enzyme having tyrosine phenol-lyase activity into a coryneform bacterium as a host. Also provided is a process for producing phenol, which comprises a step of allowing the transformant to react in a reaction mixture containing tyrosine, a salt thereof, or an ester thereof under reducing conditions, and a step of collecting phenol from the reaction mixture. | 2013-10-10 |
20130267001 | Processes for Extraction of Sugar From Sugar-Bearing Plant Material - The invention provides processes for the extraction of sugar from sugar-bearing plant material such as sugar cane. Accordingly, in one aspect of the invention, a process for extracting sugar from sugar-bearing plant material comprises contacting the sugar-bearing plant material with an extractant solution comprising water and a surfactant; and separating the extractant solution from the sugar-bearing plant material. One example of a suitable surfactant is a poly(alkylene oxide) polymer such as a poly(propylene oxide) polymer, a poly(ethylene oxide) polymer, or a poly(propylene oxide)/(ethylene oxide) copolymer. | 2013-10-10 |
20130267002 | Polypeptides Having Glucoamylase Activity And Polynucleotides Encoding Same - The present invention relates to polypeptides having glucoamylase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 2013-10-10 |
20130267003 | Methods for Culturing Cells in an Alternating Ionic Magnetic Resonance (AIMR) Multiple-Chambered Culture Apparatus - Provided herein are methods for culturing cells, tissues or organoid bodies in the presence of a pulsating alternating ionic magnetic resonance field and models comprising a tissue-like assembly of the cells so cultured. The cells, tissues or organoid bodies are introduced into a culture unit comprising growth and nutrient modules in which the gravity vector of the growth unit is continually randomized and cultured in the presence of the alternating ionic magnetic resonance field. | 2013-10-10 |
20130267004 | POLYSILICATE-POLYSILICONE ENZYME IMMOBILIZATION MATERIALS - The present invention generally relates to improvements in enzyme immobilization, particularly for use in the field of carbon dioxide capture and sequestering. It has been discovered that the utilization of sol-gel processes to immobilize enzymes in polysilicate-polysilicone copolymer coatings and particles, and the deposition of these coatings on solid state supports or use of suspensions of these particles, provides significant benefits for use in industrial applications involving enzymatic catalysts. | 2013-10-10 |
20130267005 | MICROFLUIDIC FLUID SEPARATOR AND RELATED METHODS - A microfluidic fluid separator for separating target components of a fluid by filtration is described. Methods for separating target components of a fluid by filtration and methods for processing blood on a large scale with the microfluidic fluid separator are provided. | 2013-10-10 |
20130267006 | Enzyme-Altered Metabolite Activity - The present invention relates to mutant alcohol dehydrogenase enzymes, microorganisms comprising same, and methods for the production of one or more products by microbial fermentation using said microorganisms. | 2013-10-10 |
20130267007 | AMADORIASE HAVING ALTERED SUBSTRATE SPECIFICITY - This invention provides an amadoriase having high substrate specificity to fructosyl valyl histidine. Such amadoriase comprises substitution of one or more amino acid residues at positions corresponding to amino acids selected from the group consisting of position 98, position 259, position 154, position 125, position 261, position 263, position 106, position 103, position 355, position 96, position 66, position 67, position 70, position 100, position 110, position 113, position 114, and position 156 in the amadoriase derived from the genus | 2013-10-10 |
20130267008 | FREEZING MEDIUM COMPOSITION FOR CRYOPRESERVING AMNIOTIC FLUID-DERIVED STEM CELLS AND A METHOD FOR CRYOPRESERVING THE SAME - Provided are to a freezing medium composition for cryopreserving amniotic fluid-derived stem cells, which has A lower concentration of Me | 2013-10-10 |
20130267009 | Rationally-Designed Single-Chain Meganucleases With Non-Palindromic Recognition Sequences - Disclosed are rationally-designed, non-naturally-occurring meganucleases in which a pair of enzyme subunits having specificity for different recognition sequence half-sites are joined into a single polypeptide to form a functional heterodimer with a non-palindromic recognition sequence. The invention also relates to methods of producing such meganucleases, and methods of producing recombinant nucleic acids and organisms using such meganucleases. | 2013-10-10 |
20130267010 | Immuno-Based Retargeted Endopeptidase Activity Assays - The present specification discloses a retargeted endopeptidase pharmaceutical wherein the activity has been determined by the methods disclosed. | 2013-10-10 |
20130267011 | Method For Rapidly Developing Gene Switches And Gene Circuits - Provided are: a selection method for a gene switch and a gene circuit, including using, as a selector, an expression vector containing at least a gene sequence whose expression is controlled by a transcription regulatory factor to be expressed when a genetic switch and a genetic circuit including the genetic switch operate, and a promoter sequence operably linked to the gene sequence upstream thereof; and an expression vector to be used in the selection method. This enables an effective selection method for a genetic switch and a genetic circuit, the selection method being able to be conducted within a short time period and with high selection efficiency and less leakiness. | 2013-10-10 |
20130267012 | Host Cells and Methods for Producing Diacid Compounds - The present invention provides for a method of producing one or more fatty acid derived dicarboxylic acids in a genetically modified host cell which does not naturally produce the one or more derived fatty acid derived dicarboxylic acids. The invention provides for the biosynthesis of dicarboxylic acid ranging in length from C3 to C26. The host cell can be further modified to increase fatty acid production or export of the desired fatty acid derived compound, and/or decrease fatty acid storage or metabolism. | 2013-10-10 |
20130267013 | METHODS FOR ISOLATION, USE AND ANALYSIS OF FERRITIN - This invention provides methods of isolating ferritin from plant and animal material. The isolated ferritin can be administered to humans or animals in need of iron, and can be used to treat or supplement iron deficiency. The isolated ferritin can be used in industrial applications, such as increasing the iron content in heat-processed food or beverages. The methods of the invention also include quantitation of iron derived from plant or animal ferritin. | 2013-10-10 |
20130267014 | DEVICE FOR ANALYZING THE EFFECT OF A GASEOUS MEDIUM ON A BIOLOGICAL TEST SYSTEM USING AN EXTRACELLULAR METABOLIZATION SYSTEM - The invention relates to a method for analyzing the effect of a gaseous medium on a biological test system using an extracellular metabolization system. The method consists of the following steps: a biological test sample is cultivated on a permeable carrier, the gaseous medium is guided over the surface of the biological test system in order to form an exposition atmosphere over the biological test system, the extracellular metabolization system is added to a conservation medium and the permeable carrier is brought into contact with a conservation medium that comprises the extracellular metabolization system below the permeable carrier, in such a manner that the extracellular metabolization system only passes through the permeable carrier and that the biological test system is not submerged by the conservation medium containing the extracellular metabolization system. | 2013-10-10 |
20130267015 | Fluidic Interfacing System and Assembly - A fluidic assay system assembly comprising: (a) a disposable fluidic cartridge ( | 2013-10-10 |
20130267016 | SYSTEM AND CARTRIDGE FOR EFFICIENT NUCLEIC ACID TESTING - A disposable and inexpensive biological diagnostic cartridge for the amplification and detection of nucleic acids includes a configuration having a reaction pouch for amplification which is compressed by a flexible pump pouch for detection of the amplified reaction. | 2013-10-10 |
20130267017 | Portable Coagulation Monitoring Device for Assessing Coagulation Response - A device, system and method is disclosed in which small volume blood samples are subjected to shear forces and shear stresses between two parallel planar surfaces to which linear motion trajectories are imparted. The formation of clots or coagulation of the sample is measured from dynamic mechanical coupling which occurs between the two parallel planar surfaces. Detection of the coagulation response can be achieved through optical probing or by measurement of physical effects of the blood sample binding to the planar surfaces, and restricting movement thereof. | 2013-10-10 |
20130267018 | METHOD FOR PREPARING PELLETS FROM RICE HUSK AND APPARATUS FOR REMOVING ODOR USING RICE HUSK PELLET BIO-MEDIA - A method for preparing pellets from rice husk includes: grinding rice husk; adding ammonia water to a mixture of ethylene vinyl acetate and poly(vinylacetate) to prepare a mixed, liquid binder; mixing the mixed, binder with the ground rice husk to obtain a binder/rice husk mixture; extruding the binder/rice husk mixture through an extruder; and cooling the extruded mixture at room temperature. | 2013-10-10 |
20130267019 | CELL CULTURE INSERT - A cell culture device allows co-cultivation on both sides of a membrane and has an outer tubular body with upper end having an opening and lower end closed by the membrane, an inner surface and an outer surface, which can be colonized with biological material, a complementary tubular body whose inner diameter fits onto the outer diameter of the lower end and a hanger component with upper end and a lower end. A flange extends from the upper end and the outer diameter component fits the inner diameter of the outer tubular body. The outer tubular body in a first step is connected to the complementary tubular body to form a standing insert for a first cell cultivation, and in a second step wherein the outer tubular body is disengaged from the complementary tubular body and is attached to the hanger component for a second cell cultivation. | 2013-10-10 |
20130267020 | Alternating Ionic Magnetic Resonance (AIMR) Multiple-Chambered Culture Apparatus - Provided herein are a culture apparatus, culture systems and an alternating ionic magnetic resonance electromagnetic chamber for culturing cells, tissues or organoid bodies or for delivering a pulsating alternating ionic magnetic resonance field to an object of interest including the above or to an animal, human or plant. The culture apparatus comprises a culture unit having growth and nutrient modules and a randomizing adapter to continually randomize the gravity vector in the growth module. The culture systems further comprise the alternating ionic magnetic resonance electromagnetic chamber. | 2013-10-10 |
20130267021 | SYSTEM AND METHOD OF MODULAR CLONING - System for producing a nucleic acid construct of interest, said system comprising: a set of n entry DNAs numbered 1 to n, n being an integer of at least 2, each of said n entry DNAs comprising in this order: (i) a type IIs restriction endonuclease recognition site followed by the cleavage site thereof; (ii) a sequence portion linking the cleavage site of said recognition site of item (i) with the cleavage site of the recognition site of the following item (iii), and (iii) a cleavage site of a further type Ms restriction endonuclease recognition site followed by the recognition site of said cleavage site; the cleavage sites of the type IIs restriction endonuclease recognition sites of item (iii) of entry DNAs 1 to n−1 are complementary to the cleavage sites of the type IIs restriction endonuclease recognition sites of item (i) of entry DNAs 2 to n, respectively; the cleavage site of the type Ms restriction endonuclease recognition site of item (iii) of entry DNA n is complementary to the cleavage site of the type IIs restriction endonuclease recognition site of item (i) of entry DNA 1 for allowing annealing of complementary single-stranded overhangs formed by restriction at recognition site (i) of entry DNA 1 and at recognition site (iii) of entry DNA n; said system further comprising a destination vector comprising in this order: (I) a type Ms restriction endonuclease recognition site followed by the cleavage site thereof; (II) a vector backbone preferably comprising a selectable marker gene, said vector backbone linking the cleavage sites of said recognition sites of items (I) and the following item (III); (III) a further cleavage site of a type Ms restriction endonuclease recognition site followed by the recognition site of said cleavage site, and (IV) optionally, an insert between the recognition sites of item (III) and item (i); said cleavage sites of items (I) and (III) being different and non-complementary, said recognition sites of items (I) and (III) being preferably recognitions sites of the same endonuclease. | 2013-10-10 |
20130267022 | Therapeutic Inhibitors of PAI-1 Function Methods of Their Use - The invention relates to mammalian PAI-I ligands and modulators. In particular, the invention relates to polypeptides, polypeptide compositions and polynucleotides that encode polypeptides that are ligands and/or modulators of PAI-I. The invention also relates to polyligands that are homopolyligands or heteropolyligands that modulate PAI-I activity. The invention also relates to ligands and polyligands localized to a region of a cell. The invention also relates to localization tethers and promoter sequences that can be used to provide spatial control of the PAI-I ligands and polyligands. The invention also relates to inducible gene switches that can be used to provide temporal control of the PAI-I ligands and polyligands. The invention also relates to methods of treating or preventing atherosclerosis. The invention also relates to methods of treating or preventing fibrosis. | 2013-10-10 |
20130267023 | Multiple Inducible Gene Regulation System - The present invention relates to the field of biotechnology or genetic engineering. More specifically, the present invention relates to a multiple inducible gene regulation system that functions within cells to simultaneously control the quantitative expression of multiple genes. | 2013-10-10 |
20130267024 | NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 282P1G3 USEFUL IN TREATMENT AND DETECTION OF CANCER - A novel gene 282P1G3 and its encoded protein, and variants thereof, are described wherein 282P1G3 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 282P1G3 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 282P1G3 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 282P1G3 can be used in active or passive immunization. | 2013-10-10 |
20130267025 | Partial Region Polypeptide of REIC/Dkk-3 Protein - A polypeptide capable of strongly inducing and activating dendritic-cell-like cells for treating or prevent cancer by immunotherapy, and DNA encoding the polypeptide. The polypeptide is a polypeptide (a) or (b) consisting of a partial region of the REIC/Dkk-3 protein. | 2013-10-10 |
20130267026 | METHODS OF BUILDING A BODY PORTION - An improved method of implanting cells in the body of a patient includes positioning viable cells on a support structure. One or more blood vessels may be connected with the support structure to provide a flow of blood through the support structure. A support structure may be positioned at any desired location in a patient's body. The support structure may be configured to replace an entire organ or a portion of an organ. An organ or portion of an organ may be removed from a body cells and/or other tissue is removed to leave a collagen matrix support structure having a configuration corresponding to the configuration of the organ or portion of an organ. Alternatively, a synthetic support structure may be formed. The synthetic support structure may have a configuration corresponding to a configuration of an entire organ or only a portion of an organ. | 2013-10-10 |
20130267027 | DRY GRANULATED CELL CULTURE MEDIA - The present invention relates dry granulated cell culture media which do not comprise peptones or tryptones, especially to dry granulated cell culture media formulations that support the growth of mammalian, and/or insect and/or plant cells. The present invention further relates to the production of these dry granulated cell culture media and their use. | 2013-10-10 |
20130267028 | Recombinant Influenza Viruses for Vaccines and Gene Therapy - The invention provides a composition useful to prepare influenza A viruses, e.g., in the absence of helper virus. | 2013-10-10 |
20130267029 | MANIPULATION OF STEM CELL FUNCTION BY P53 ISOFORMS - This invention provides methods and compositions for increasing the efficiency of obtaining pluripotent stem cells, the method comprising expressing a 133p53 in cells that are being re-programmed to obtain pluripotent cells. The invention also provides method of inhibiting the proliferation of cancer stem cells, the method comprising suppressing expression of 133p53 in the cells. | 2013-10-10 |
20130267030 | EFFICIENT METHOD FOR ESTABLISHING INDUCED PLURIPOTENT STEM CELLS - The invention provides a method of improving the efficiency of establishment of induced pluripotent stem cells by increasing, in a nuclear reprogramming step of somatic cell, the level of activated form of one or more proteins selected from the group consisting of Ras family members, PI3 kinase, RalGEF, Raf, AKT family members, Rheb, TCL1 and S6K. The invention also provides a method of producing induced pluripotent stem cells by contacting a somatic cell with a nuclear reprogramming substance and one or more of such proteins and nucleic acids that encode such proteins. The invention further provides an induced pluripotent stem cell that has an exogenous nucleic acid encoding such a protein, as well as agents for use in the aforesaid methods. | 2013-10-10 |
20130267031 | Method for Measuring Neuropeptide Y in Biological Samples - The present invention provides methods for determining the amount of NPY in a biological sample using mass spectrometry. The methods involve specific sample collection processes necessary to stabilize and facilitate NYP analyses. Once in the laboratory, sample preparation is followed by on-line extraction, liquid chromatographic separation of relevant moieties with detection by MS/MS whereby specific ion transitions are monitored. This invention has several clinical utilities related to disease processes and patient assessment. | 2013-10-10 |
20130267032 | TEST STRIPS AND METHOD FOR READING TEST STRIPS - A specimen test strip is provided to detect a characteristic of an analyte in a specimen sample. The specimen test strip includes a reaction area to receive the specimen sample and a color calibration area to determine a color, or a color and a color intensity, of the reaction area after receiving the specimen sample. The specimen test strip may further include a temperature indication area to correct a measurement of the characteristic of analyte. | 2013-10-10 |
20130267033 | Detection cell with controlled power dissipation - A voltage control circuitry for a detection cell ( | 2013-10-10 |
20130267034 | INTERMOLECULAR INTERACTION MEASUREMENT METHOD, MEASUREMENT SYSTEM FOR USE IN THE METHOD, AND PROGRAM - A measuring method of an intermolecular interaction for optically measuring an intermolecular interaction between a plurality of substances on a thin film, the method comprising: detecting intensity at a first wavelength of reflected light or transmitted light before start of the intermolecular interaction with a detection unit which detects the reflected light from the thin film or the transmitted light transmitted through the thin film; detecting intensity at the first wavelength of the reflected light or the transmitted light after the start of the intermolecular interaction with the detection unit; and calculating a difference in intensity of the reflected light or the transmitted light at the first wavelength between before and after the start of the intermolecular interaction. | 2013-10-10 |
20130267035 | Isotopic Chemical Analysis using Optical Spectra from Laser Ablation - This disclosure provides systems, methods, and apparatus related to performing isotopic analysis of a sample. In one aspect a method includes applying laser energy to a region of a sample with a laser to generate a plasma and recording a spectrum generated by a plurality of molecular species in the plasma with a device. | 2013-10-10 |
20130267036 | LONGEVITY OF HYPERPOLARIZED ENHANCED SIGNALS FOR 'H NMR SPECTROSCOPY - A method and system for providing an article of manufacture with increased longevity of hyperpolarized | 2013-10-10 |
20130267037 | MASS SPECTROMETER DEVICE AND METHOD USING SCANNED PHASE APPLIED POTENTIALS IN ION GUIDANCE - An ion guide or mass analyser is disclosed comprising a plurality of electrodes having apertures through which ions are transmitted in use. A pseudo-potential barrier is created at the exit of the ion guide or mass analyser. The amplitude or depth of the pseudo-potential barrier is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages are applied to the electrodes of the ion guide or mass analyser in order to urge ions along the length of the ion guides or mass analyser. The amplitude of the transient DC voltage applied to the electrode may be increased with time so that ions are caused to be emitted from the ion guide or mass analyser in reverse order of their mass to charge ratio. | 2013-10-10 |
20130267038 | MICROPLATE GUIDE FOR A PIPETTE - Microplate guide for a pipette, said guide comprising means for selecting the type of the microplate, the mode of dispensing and the dispensing direction, as well as means for indicating the next target for dispensing on the display of the pipette prior to each pipetting operation, and a method for guiding a pipetting operation, said method comprising the steps of selecting the type of microplate, selecting the mode of dispensing, and selecting the dispensing direction, followed by displaying on the display of the pipette the next target for dispensing prior to each pipetting operation. | 2013-10-10 |
20130267039 | Single Molecule Assays - The present invention provides single molecule analyses of species of use in analytical, diagnostic or prognostic assays. In exemplary embodiments, the assays utilize samples prepared by novel methods, affording assays of unexpected sensitivity and robustness. The method is described in a non-limiting manner by reference to cytokine assays. | 2013-10-10 |
20130267040 | PEPTIDE CAPABLE FOR BINDING TO RHODIUM - The present invention provides a novel peptide capable for binding to rhodium. The peptide consists of an amino acid sequence represented by SQMMGHMGHGNMNHMNHGGKFDFHH. | 2013-10-10 |
20130267041 | METHODS FOR ISOLATION, USE AND ANALYSIS OF FERRITIN - This invention provides methods of isolating ferritin from plant and animal material. The isolated ferritin can be administered to humans or animals in need of iron, and can be used to treat or supplement iron deficiency. The isolated ferritin can be used in industrial applications, such as increasing the iron content in heat-processed food or beverages. The methods of the invention also include quantitation of iron derived from plant or animal ferritin. | 2013-10-10 |
20130267042 | MRAM Fabrication Method with Sidewall Cleaning - Fabrication methods for MRAM are described wherein any re-deposited metal on the sidewalls of the memory element pillars is cleaned before the interconnection process is begun. In embodiments the pillars are first fabricated, then a dielectric material is deposited on the pillars over the re-deposited metal on the sidewalls. The dielectric material substantially covers any exposed metal and therefore reduces sources of re-deposition during subsequent etching. Etching is then performed to remove the dielectric material from the top electrode and the sidewalls of the pillars down to at least the bottom edge of the barrier. The result is that the previously re-deposited metal that could result in an electrical short on the sidewalls of the barrier is removed. Various embodiments of the invention include ways of enhancing or optimizing the process. The bitline interconnection process proceeds after the sidewalls have been etched clean as described. | 2013-10-10 |
20130267043 | Magnetic Field Sensors and Methods for Fabricating the Magnetic Field Sensors - Magnetic field sensors and associated methods of manufacturing the magnetic field sensors include molded structures to encapsulate a magnetic field sensing element and an associated die attach pad of a lead frame and to also encapsulate or form a magnet or a flux concentrator. | 2013-10-10 |
20130267044 | SUPERIOR INTEGRITY OF HIGH-K METAL GATE STACKS BY PRESERVING A RESIST MATERIAL ABOVE END CAPS OF GATE ELECTRODE STRUCTURES - When forming high-k metal gate electrode structures in a semiconductor device on the basis of a basic transistor design, undue exposure of sensitive materials at end portions of the gate electrode structures of N-channel transistors may be avoided, for instance, prior to and upon incorporating a strain-inducing semiconductor material into the active region of P-channel transistors, thereby contributing to superior production yield for predefined transistor characteristics and performance. | 2013-10-10 |
20130267045 | SHOWER HEAD APPARATUS AND METHOD FOR CONTROLLIGN PLASMA OR GAS DISTRIBUTION - An apparatus comprises: a shower head having a supply plenum for supplying the gas to the chamber and a vacuum manifold fluidly coupled to the supply plenum; and at least one vacuum system fluidly coupled to the vacuum manifold of the shower head. | 2013-10-10 |
20130267046 | METHOD FOR FABRICATION OF A SEMICONDUCTOR DEVICE AND STRUCTURE - A method to process an Integrated Circuit device including processing a first layer of first transistors, then processing a first metal layer overlaying the first transistors and providing at least one connection to the first transistors, then processing a second metal layer overlaying the first metal layer, then processing a second layer of second transistors overlaying the second metal layer, wherein the second metal layer is connected to provide power to at least one of the second transistors. | 2013-10-10 |
20130267047 | Topography-Aware Lithography Pattern Check - The present disclosure provides a method. The method includes obtaining an integrated circuit (IC) layout. The method includes providing a polishing process simulation model. The method includes performing a lithography pattern check (LPC) process to the IC layout. The LPC process is performed at least in part using the polishing process simulation model. The method includes detecting, in response to the LPC process, possible problem areas on the IC layout. The method includes modifying the polishing process simulation model. The method includes repeating the performing the LPC process and the detecting the possible problem areas using the modified polishing process simulation model. | 2013-10-10 |
20130267048 | Structure and Method for Placement, Sizing and Shaping of Dummy Structures - A chip includes a number a plurality of functional areas of a layer and a number of dummy structures within the layer. The dummy structures are spaced from the functional areas. Each dummy structure has a size that is a function of the size and density of the functional areas. | 2013-10-10 |
20130267049 | METHOD FOR PRODUCING A STRUCTURE COMPRISING AT LEAST ONE ACTIVE PART HAVING ZONES OF DIFFERENT THICKNESSES - Method for producing a structure comprising an active part comprising a first and a second suspended zone of different thicknesses from a first comprising substrate, said method comprising the following steps:
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20130267050 | SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SEMICONDUCTOR DEVICE - Provided is a semiconductor device and a method of manufacturing the semiconductor device, in which the semiconductor device has a semiconductor element having a plurality of wires bonded to the semiconductor element with sufficient bonding reliability and has a good heat dissipation property. A semiconductor device in which a first wire is ball bonded on an electrode, and a second wire is further bonded on the ball-bonded first wire, and the first wire or an end of the second wire defines a space between itself and the ball portion of the first wire. | 2013-10-10 |
20130267051 | Method for Producing a Luminescence Conversion Substance Layer, a Composition Therefor and a Component Comprising such a Luminescence Conversion Substance Layer - One embodiment of the invention describes a method for producing a luminescence conversion substance layer on a substrate with a semiconductor element that emits a primary radiation during operation. A composition includes a luminescence conversion substance, a matrix material and a solvent. The composition is applied to a substrate. At least part of the solvent is removed, with the result that the luminescence conversion substance layer is formed on the substrate. | 2013-10-10 |
20130267052 | SEMICONDUCTOR LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING THE SAME - A method for manufacturing a semiconductor light emitting device includes forming a lower cladding layer over a GaAs substrate; forming a quantum dot active layer over the lower cladding layer; forming a first semiconductor layer over the quantum dot active layer; forming a diffraction grating by etching the first semiconductor layer; forming a second semiconductor layer burying the diffraction grating; and forming an upper cladding layer having a conductive type different from that of the lower cladding layer over the second semiconductor layer, wherein the processes after forming the quantum dot active layer are performed at a temperature not thermally deteriorating or degrading quantum dots included in the quantum dot active layer. | 2013-10-10 |
20130267053 | METHOD FOR MANUFACTURING MOTHER SUBSTRATE AND ARRAY SUBSTRATE - The present invention relates to a method for manufacturing a mother substrate, the mother substrate comprising: a substrate comprising at least one display region and pre-cutting regions in a periphery of the display region, wherein the display region comprises gate scanning lines and data scanning lines, the pre-cutting regions comprise a gate-line connecting line and a data-line connecting line electrically connected to each other, and the gate-line connecting line is electrically connected to all of the gate scanning lines in the display region, and the data-line connecting line is electrically connected to all of the data scanning lines in the display region substrate. | 2013-10-10 |