42nd week of 2017 patent applcation highlights part 39 |
Patent application number | Title | Published |
20170299530 | COMPOUNDS AND METHODS FOR ANALYSIS AND SYNTHESIS OF SACCHARIDE COMPOUNDS, AND METHOD FOR QUANTITATING SACCHARIDE - Provided is a method for quantitating a saccharide in a liquid sample. The method comprises incubating the liquid sample with 2,3-naphthalenediamine in the presence of iodine to allow a naphthimidazole group to be linked to the saccharide to obtain a first mixture; obtaining an | 2017-10-19 |
20170299531 | Evaluating Performance of a Fluid Transport System Using Limited Sensor Data - Embodiments of the disclosure relate to systems and methods to evaluate performance of a fluid transport system. Towards this end, a performance report of the fluid transport system can be generated by estimating various performance parameters at an outlet of a heat exchanger in lieu of using sensor data obtained directly from the outlet of the heat exchanger. Specifically, in one exemplary implementation, sensor data is obtained from an inlet of the heat exchanger and an outlet of a downstream element that is coupled to the heat exchanger, for estimating the various performance parameters at the outlet of the heat exchanger. The estimated performance parameters can then be combined with empirical data and predictive data for generating the performance report of the fluid transport system. | 2017-10-19 |
20170299532 | DIFFERENTIAL SCANNING CALORIMETRY METHOD AND APPARATUS - A method of determining thermal properties of a sample using differential scanning calorimetry (DSC), the method comprises injecting a first separation fluid, a sample plug, and a second separation fluid into a sample cell. The first separation fluid and the sample plug have a first separation interface, and the sample plug and the second fluid have a second separation interface. The method further comprises injecting a reference fluid into a reference cell, heating the sample cell and reference cell, and determining thermal properties of the sample using DSC analysis. | 2017-10-19 |
20170299533 | CONTROL APPARATUS FOR ROTATING DEVICE - A control apparatus for rotating device includes a plurality information sensors and a controller. The information sensors are coupled to the rotating device for sensing temperature information, acoustic information and vibration information. The controller receives the temperature information, the acoustic information and the vibration information at a plurality of consecutive sampling time points to respectively obtain a plurality of sampled temperature values, a plurality of sampled noise values, and a plurality of sampled vibration values, during a time period. The controller generates a plurality of status signals corresponding to the sampling time points according to the sampled temperature values, the sampled noise values and the sampled vibration values. The controller generates a control signal according to the status signals, and transports the control signal to control an operation of the rotating device. | 2017-10-19 |
20170299534 | ANALYSIS SYSTEM AND ANALYSIS METHOD - A heat source position inside a measurement object is identified with high accuracy by improving time resolution. | 2017-10-19 |
20170299535 | DETECTING DEVICE AND DETECTING METHOD FOR DETECTING A USAGE STATE OF A SOCKET - A detecting device for detecting a usage state of a socket includes a carrier, a movable assembly and a conductivity detecting module. The carrier has a first plug hole and a second plug hole. The movable assembly is movably disposed in the carrier. The conductivity detecting module is disposed on the carrier. The movable assembly is moved for exposing the first plug hole and the second plug hole by an external pushing force, and a detecting signal of the socket in-use is generated by the conductivity detecting module according to movement of the movable assembly. | 2017-10-19 |
20170299536 | GAS ANALYZER AND GAS ANALYSIS METHOD - A gas analyzer including: a chamber; a first gas sensor provided in the chamber and including a first gas sensitive member; a second gas sensor provided in the chamber and including a second gas sensitive member; and a detector that detects each of resistance changes of the first and the second gas sensitive members; wherein the first gas sensitive member is an oxide semiconductor mainly composed of at least one of Sn, W, Zn and In or a semiconductor mainly composed of C, and the second gas sensitive member is mainly composed of a halide or an oxide of Cu or Ag. | 2017-10-19 |
20170299537 | METHODS FOR IN SITU MONITORING AND CONTROL OF DEFECT FORMATION OR HEALING - Production of perforated two-dimensional materials with holes of a desired size range, a narrow size distribution, and a high and uniform density remains a challenge, at least partially, due to physical and chemical inconsistencies from sheet-to-sheet of the two-dimensional material and surface contamination. This disclosure describes methods for monitoring and adjusting perforation or healing conditions in real-time to address inter- and intra-sheet variability. In situ or substantially simultaneous feedback on defect production or healing may be provided either locally or globally on a graphene or other two-dimensional sheet. The feedback data can be used to adjust perforation or healing parameters, such as the total dose or efficacy of the perforating radiation, to achieve the desired defect state. | 2017-10-19 |
20170299538 | APPARATUS AND METHODS FOR PROVIDING DUAL-LAYER ENZYMATIC SENSOR - An enzymatic sensor and processes for making an enzymatic sensor are disclosed. In some implementations, a sensor is provided that includes a gel-enzyme layer for reacting with an analyte of interest to create an electrical signal corresponding to a concentration of the analyte in a sample. In addition, a cushion layer formed on the gel-enzyme layer to attenuate the effects of mechanical perturbations on the gel-enzyme layer and its concomitant distortion of a signal output of the sensor. | 2017-10-19 |
20170299539 | SYSTEMS AND METHODS FOR ELECTROCHEMICAL TRIGLYCERIDES ASSAYS - A system for the electrochemical detection of triglyceride levels includes a test strip including an electrode and a counter electrode, the electrode and counter electrode located proximate to a sample reception area; and a coating on one of the electrode and counter electrode, the coating including a reagent coating for triglycerides. | 2017-10-19 |
20170299540 | METHOD FOR MEASURING AN ANALYTE IN A SAMPLE - A sensor system including devices and methods for determining the concentration of an analyte in a sample is described. Input signals including amperometric and voltammetric duty cycles of excitations and relaxations may provide a shorter analysis time and/or improve the accuracy and/or precision of the analysis. The disclosed system may reduce analysis errors, thus improving measurement performance, by adjusting the potential and/or scan rate in response to output currents obtained from voltammetric scans. The disclosed system also may determine the concentration of more than one ionizable species in the sample by adjusting the potential and/or scan rate in response to output currents obtained from voltammetric scans. The multiple, determined concentrations may be used to determine the concentration of multiple analytes or to correct the concentration determined for an analyte, thus improving the measurement performance of the system. | 2017-10-19 |
20170299541 | METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS - A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes. | 2017-10-19 |
20170299542 | ELECTROCHEMICAL CHLORINE GAS SENSOR AND FABRICATION THEREOF - An electrochemical chlorine gas sensor is disclosed with a working electrode, a counter electrode, and a reference electrode. The working electrode may be coated with a nanoporous gold layer, a first solution comprising an ionic liquid, and a second solution that may be selected from a Nation solution, a chitosan solution, an agar solution, or combinations thereof. The reference and counter electrodes may be further coated with the ionic liquid. | 2017-10-19 |
20170299543 | NITROGEN OXIDE BASED GAS SENSOR, OXYGEN PUMP, GAS SENSOR APPARATUS, MANUFACTURING METHOD OF GAS SENSOR APPARATUS, AND SENSOR NETWORK SYSTEM - A nitrogen oxide based gas sensor includes: a substrate provided with a beam structure having a MEMS structure; a heater disposed on the substrate; a lower electrode disposed on the heater, a solid electrolyte layer disposed on the lower electrode; an upper electrode disposed on a surface of the solid electrolyte layer facing the lower electrode and configured to introduce a measurement target gas; a cavity portion formed in the substrate; and a gas flow path disposed so as to connect the cavity portion and the lower electrode, wherein the gas sensor is configured to detect a concentration of nitrogen oxide in the measurement target gas. | 2017-10-19 |
20170299544 | 2H/1T Phase Contact Engineering for High Performance Transition Metal Dichalcogenide Chemical Vapor Sensors - A method of making a low dimensional material chemical vapor sensor comprising providing a monolayer of a transition metal dichalcogenide, applying the monolayer to a substrate, applying a PMMA film, defining trenches, and placing the device in a n-butyl lithium (nbl) bath. A low dimensional material chemical vapor sensor comprising a monolayer of a transition metal dichalcogenide, the monolayer applied to a substrate, a region or regions of the transition metal dichalcogenide that have been treated with n-butyl lithium, the region or regions of the transition metal dichalcogenide that have been treated with n-butyl lithium have transitioned from a semiconducting to metallic phase, metal contacts on the region or regions of the transition metal dichalcogenide that have been treated with the n-butyl lithium. | 2017-10-19 |
20170299545 | SENSOR PACKAGE HAVING AN ELECTRICAL CONTACT - Sensor package is provided that includes a package housing defining a receiving cavity and having a package side. The package side includes a detector opening therethrough. The sensor package also includes a sensor module held by the package housing and disposed within the receiving cavity. The sensor module has a sensor side that is aligned with the detector opening such that the sensor side is exposed to a detection space. The sensor module also includes a conductive pathway that is configured to transmit signals that are based on an environmental parameter detected by the sensor module. The sensor package also includes an electrical contact that is coupled to the package housing. The electrical contact includes a contact finger. The contact finger is engaged to the conductive pathway and exerts a normal force against the conductive pathway. | 2017-10-19 |
20170299546 | ELECTROCHEMICAL SENSOR - An electrochemical sensor for potentiometric measurements in a measurement medium has a sensor head ( | 2017-10-19 |
20170299547 | CAPILLARY ELECTROPHORESIS APPARATUS - A pump is used to draw in a sample into a sample suction tube, and the sample is introduced into a capillary tube that is disposed straight in the horizontal direction. Because the sample is drawn in through the sample suction tube in this way, there is no need to bend the capillary tube so as to dip an end portion thereof into the sample. The result is that there is no need to lengthen the capillary tube to compensate for the degree of separation that is lost through bending of the capillary tube, and thus the capillary tube may be shorter, enabling the analysis to be performed more quickly and with higher throughput. | 2017-10-19 |
20170299548 | Nucleic Acid Delivery Controlling System and Method for Manufacturing Same, and Nucleic Acid Sequencing Device - The present invention provides: a nucleic acid delivery controlling system in which a novel delay principle is utilized to greatly delay the nanopore passing rate of a nucleic acid strand, thereby enabling the stable analysis of a nucleotide sequence; a method for manufacturing the nucleic acid delivery controlling system; and a nucleic acid sequencing device. The present invention relates to a nucleic acid delivery controlling system, equipped with a passage through which a nucleic acid strand can pass, said nucleic acid delivery controlling system being characterized in that the passage through which a nucleic acid strand can pass has at least one nanochannel having multiple passages per one nanopore through which only one molecule of the nucleic acid strand can pass, the nanochannel has a microphase-separated structure composed of a block copolymer that is composed of a hydrophobic polymer chain and a hydrophilic polymer chain, and the nanochannel contains the hydrophilic polymer chain of the block copolymer as the main component. | 2017-10-19 |
20170299549 | System and Method For the Separation of Analytes - A separation module operates to fractionate or separate an analyte into fractions according to pI, i.e., pI bands, utilizing capillary isoelectric focusing (“CIEF”) within a first microchannel. The fractions are stacked to form plugs, the number of which is determined by a number of parallel second microchannels integrally connected to the first microchannel, into which the fractions are directed according to the buffer characteristics found in each of the individual microchannels. Within the microchannels the plugs are separated into proteins according to a different chemical property, i.e., “m/z,” utilizing capillary electrophoresis (“CE”). | 2017-10-19 |
20170299550 | WIDEBAND ISOLATION DIRECTED BY ION MOBILITY SEPARATION FOR ANALYZING COMPOUNDS - In an ion mobility-mass spectrometry (IM-MS) system, an ion mass-isolated data set is acquired by operating a mass filter to apply a mass isolation window having an m/z width such that the mass isolation window moves through a sequence of window positions, each window position being defined by an IM drift time value and an m/z ratio value. The m/z width of the mass isolation window and the sequence of window positions are determined such that the mass isolation window captures ions in a region of interest of a larger all-ions data set. The isolation window may be a wideband isolation window. In comparison to the all-ions data set, the mass-isolated data set may yield reduced ion signal interference and increased selectivity for analytes of interest. | 2017-10-19 |
20170299551 | FAST-SWITCHING DUAL-POLARITY ION MOBILITY SPECTROMETRY - Systems and methods disclosed provide for methods of managing polarity switching in an ion mobility spectrometer, and provide for management of the repelling grid voltage, the gating grid voltage, and the fixed grid voltage during polarity switching. Systems and methods also provide for the management of the effect of dielectric relaxation in an insulator proximal to the collector, and provide for a preamplifier coupled to the collector including a switch, and a method of managing the collector output including the switch. Systems and methods consistent with the current disclosure further provide for a method of normalizing ion mobility data by determining fitting coefficients associated with a plurality of measurement data sets, and subtracting the curves determined by the fitting coefficients from the data acquired by the ion mobility spectrometer. | 2017-10-19 |
20170299552 | Ultrasonic-Based System for Detection of Metallic Security Threats Containers on Cargo - Proactively identifying and interdicting transport of commodities associated with illicit nuclear materials and nuclear weapons shielded by high Z-number materials, such as lead, can help ensure effective nuclear nonproliferation. In an embodiment, a method for imaging an object on a surface includes exciting a surface with ultrasonic excitation from an ultrasonic transmitter having an ultrasonic transducer in contact with the surface. The method further includes imaging, at a processor, a two-dimensional representation of the object acoustically coupled to the surface based on the ultrasonic reflections received at an ultrasonic receiver via a receiving transducer in contact with the surface. This method can complement existing x-ray screening systems to increase the odds of detecting radiological materials. | 2017-10-19 |
20170299553 | PHOTOACOUSTIC MICROSCOPE OBJECTIVE LENS UNIT AND PHOTOACOUSTIC MICROSCOPE INCLUDING THE SAME - A photoacoustic microscope objective lens unit includes: an objective lens which irradiates a sample with excitation light L; a photoacoustic wave detection unit which detects a photoacoustic wave U generated from the sample; and a photoacoustic wave guide system. The photoacoustic wave guide system includes: a photoacoustic wave separation member; and an acoustic lens that is disposed between the photoacoustic wave separation member and the sample and has a focus position that substantially matches with a focus position of the objective lens. The acoustic lens is obtained by cementing a main acoustic lens and a correction acoustic lens to each other. The main acoustic lens and the correction acoustic lens satisfy predetermined Conditional Expressions. | 2017-10-19 |
20170299554 | COMBINED ELECTROMAGNETIC ACOUSTIC TRANSDUCER (EMAT) AND ELECTRO PERMANENT MAGNETS (EPMS) FOR BIAS FIELD CONTROL - Systems and methods for non-destructive testing of specimens are disclosed herein. In one embodiment, an electromagnetic acoustic transducer (EMAT) includes an electro-permanent magnet (EPM) configured to controllably apply a biasing magnetic flux to a target location. The EPM includes a hard magnet, and a soft magnet at least partially enclosing the hard magnet. The EPM also includes a magnetizing coil having a plurality of turns at least partially encircling the soft magnet. The magnetizing coil is configured to controllably magnetically bias the soft magnet when a current is applied to the magnetizing coil. | 2017-10-19 |
20170299555 | METHOD FOR WETTING A SONOTRODE - The method comprising the following steps:
| 2017-10-19 |
20170299556 | CHROMATOGRAPH SAMPLER AND METHOD FOR OPERATING CHROMATOGRAPH SAMPLER - In order to, in a chromatograph sampler, regulate the pressure of a sample fluid filled in a constant volume tube to be as constant as possible and ensure the reproducibility of measurement, the chromatograph sampler is configured to provide a bypass line between a sample introduction line and a sample discharge line in parallel with the constant volume tube, and when filling the sample fluid in the constant volume tube, flow the sample fluid also through the bypass line in parallel. | 2017-10-19 |
20170299557 | SIMULTANEOUS MULTICOMPOUND ANALYSIS METHOD AND SIMULTANEOUS MULTICOMPOUND ANALYSIS PROGRAM USING MASS SPECTROMETRY - The operation efficiency and accuracy of the simultaneous analysis of phospholipids, including fatty acid compositions are increased. After a first-time LC/MS/MS analysis for determining the phospholipid classes of the phospholipid contained in a sample is performed (S2-S3), a second-time LC/MS/MS analysis for determining fatty acid compositions is performed only for the detected phospholipids (S4-S8). By associating a method list in which an MRM transition for phospholipid class determination is recorded for each compound of phospholipid classes with a method list in which an MRM transition for fatty acid composition determination is recorded for each phospholipid compound, it is possible to promptly select MRM transitions for fatty acid composition determination that correspond to compounds of the detected phospholipid classes, and to easily create an analysis method for the second-time analysis. | 2017-10-19 |
20170299558 | TECHNIQUES FOR DISPLAY AND PROCESSING OF MASS SPECTRAL DATA - Processing mass spectral data may include performing one or more experiments using one or more samples, each experiment including mass analysis using a mass spectrometer; acquiring one or more raw mass spectral data sets as a result of performing the one or more experiments; receiving selection criteria; filtering the one or more raw mass spectral data sets in accordance with the selection criteria; and generating a chromatogram as a result of said filtering, wherein the chromatogram displays signal intensity as a function of scan time for a plurality of scan times and includes a non-zero signal intensity at each scan time only if, at the scan time, the selection criteria is met and otherwise the chromatogram includes a zero signal intensity at the scan time. The mass spectrometer may alternate between low and elevated energy modes and acquire two of the raw mass spectral data sets concurrently. | 2017-10-19 |
20170299559 | System and method for gas sample analysis - A method is provided for analyzing a sample and identifying species using chromatography and spectrometry. Possible candidate species to be used in a regression analysis are selected for consideration based on their retention indices in a chromatography column and peak locations in an infrared spectrum. By using such a selection process, the number of combinations of species to be used in the regression analysis can be significantly reduced. The species and respective concentrations in the sample are identified by using an iterative process with regression analysis and minimizing least squares errors between a sample spectrum and a computed spectrum associated with selected candidate species. | 2017-10-19 |
20170299560 | DERIVATIZATION APPARATUS AND METHOD - A derivatization apparatus and method for coating a sample carrier with a reagent solution. The derivatization apparatus consists of a closed system in which a small quantity of reagent solution is sprayed into a closed container via a spray nozzle. A sample carrier is located in the closed container and is coated as homogeneously as possible with the reagent solution. | 2017-10-19 |
20170299561 | Method, Device, And System For Aerosol Detection Of Chemical And Biological Threats - Methods and systems for identifying an aerosolized agent. A method for identifying an aerosolized agent includes the steps of providing a sample potentially containing an aerosolized agent, concentrating the sample with an aerosol collector, analyzing the concentrated sample on a collection substrate using spectroscopy to produce an aerosolized agent analysis output, comparing the analysis output to a database of known agent analysis outputs; identifying the aerosolized agent based on the comparison; and alerting a user to the presence of an aerosolized agent in the sample. | 2017-10-19 |
20170299562 | BELL CAP AEROSOL ADAPTOR - A method of testing an air sample and/or testing equipment may comprise introducing aerosolized sample particles into an air flow to create sample air upstream from an air quality sampling device. The method may include introducing the sample air to an offset sample inlet of a bell cap inlet adaptor coupled to a sample tube. The method may include merging at least a portion of the introduced sample air with axially flowing air with little to no turbulence based on the geometry of the bell cap inlet adaptor and/or a containment cavity. The method may include introducing at least a portion of the sample air into the sample tube. Next, a test of at least one of the quality of the sample air and/or the functionality of the bell cap inlet may be performed. | 2017-10-19 |
20170299563 | INTERCONNECTED CORRUGATED CARBON-BASED NETWORK - An interconnected corrugated carbon-based network comprising a plurality of expanded and interconnected carbon layers is disclosed. In one embodiment, each of the expanded and interconnected carbon layers is made up of at least one corrugated carbon sheet that is one atom thick. In another embodiment, each of the expanded and interconnected carbon layers is made up of a plurality of corrugated carbon sheets that are each one atom thick. The interconnected corrugated carbon-based network is characterized by a high surface area with highly tunable electrical conductivity and electrochemical properties. | 2017-10-19 |
20170299564 | CANNABIS CULTIVATION TEST - Systems and methods are disclosed to determine that a | 2017-10-19 |
20170299565 | Computing system for detecting total phosphorus in effluent using data driven A2/O process - A computing system is designed for measuring the A | 2017-10-19 |
20170299566 | Reagents For Oxidizer-Based Chemical Detection - Reagents and methods are disclosed for detection of oxidizers and inorganic salts and other analytes of interest. The reagents can interact with their target analytes, especially oxidizer compositions or oxidizer-based explosives, to selectively enhance their ionization yield, interacting by chemical reaction or by forming an associative adduct which facilitates their detection. For example, the reagents can adduct with the counter-ion of the intended analyte for improved direct detection and/or react chemically via acid-base reactions to produce a new product for detection. In another aspect of the invention, reactive reagents and methods are also disclosed that facilitate indirect detection of the analyte at lower temperatures based on reduction-oxidation (redox) chemistry. These reagents are particularly useful in detecting oxidizer analytes. | 2017-10-19 |
20170299567 | METHODS AND SYSTEMS FOR TREATING MEIBOMIAN GLAND DYSFUNCTION USING RADIO-FREQUENCY ENERGY - A method of treating meibomian gland dysfunction is disclosed. The method includes directing RF energy to an internal portion of a meibomian gland, selectively targeting an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction, and expressing the obstruction from the duct of the meibomian gland. An apparatus for treating meibomian gland dysfunction is also disclosed. The apparatus comprises at least one RF electrode configured to direct RF energy to an internal portion of a meibomian gland located in an eyelid of an eye, the at least one RF electrode further configured to selectively target an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction. The apparatus also comprises at least one expressor configured to express the obstruction from the duct of the meibomian gland. | 2017-10-19 |
20170299568 | METHOD TO DETERMINE A CETANE NUMBER OF A FUEL - A method of determining the cetane number of a fuel in an internal combustion engine comprising, during running of the engine, i) with respect to one cylinder, performing a routine including a series of injections such that for each injection a quantity of fuel is injected into the cylinder, and during the routine varying the angle at which the injections takes place with respect to crankshaft angle; ii) measuring engine speed at intervals during the series of injections and determining values for changes in engine speed consequent to the injections; iii) determining cetane number from a pre-stored relationship relating the cetane number to changes in engine speed consequent to changes in the test injection angle. | 2017-10-19 |
20170299569 | METHOD FOR EVALUATING IDENTITY OF POLYMERS AND SYSTEM USING SAME - This invention relates to a method of evaluating the identity of polymers and a system using the same, and more particularly to a novel method of evaluating the identity of polymers, wherein the identity of multiple polymers, rather than just one polymer, can be determined using only information about structures of the polymers, without the need to determine the characteristics of synthesized polymers through real-world experimentation. In order to evaluate the identity of polymers, the identity index PohoFactor(X | 2017-10-19 |
20170299570 | METHOD FOR PREDICTING CANCER PROGRESSION BY NANOMECHANICAL PROFILING - The invention relates to a method for staging metastatic potential of a primary tumour sample or related lymph node by nanomechanical measurement and/or for determing the reoccurrence or incidence potential. | 2017-10-19 |
20170299571 | Compositions and methods for determining mechanical properties of cells - Provided herein are systems and method for measuring cell stiffness. In particular, provided herein are microelectrode configuration and systems for measuring platelet deformation and stiffness. | 2017-10-19 |
20170299572 | BIOPOLYMER ANALYSIS DEVICE AND BIOPOLYMER ANALYSIS METHOD - The thin film of a thin film device used for analyzing a biopolymer breaks due to the potential difference between the solutions at both sides of the thin film. | 2017-10-19 |
20170299573 | HOST AND INTESTINAL MICROBIOTA DERIVED METABOLOMIC BLOOD PLASMA SIGNATURE FOR PRIOR RADIATION INJURY - Provided are methods of determining prior radiation dose exposure levels for subjects, and kits therefor. Also provided are methods of treatment. | 2017-10-19 |
20170299574 | METHODS OF MONITORING FOR ADHERENCE TO ARIPIPRAZOLE THERAPY - Methods for helping to monitor subject adherence with a prescribed antipsychotic drug treatment regimen are disclosed. | 2017-10-19 |
20170299575 | APPARATUS, METHOD, SYSTEM FOR THE DETERMINATION OF THE AGGREGATION RATE OF RED BLOOD CELLS - The present invention generally relates to an apparatus, method, system for the determination of the aggregation rate of red blood cells. More specifically, the invention concerns a method, system, and the relative apparatus used to determine the aggregation rate of red blood cells, and other parameters related to these, such as viscosity, deformability, elasticity, density, in the field of in vitro medical analyses, using optical systems after or during inducted forces for red blood cell disruption and redistribution generated by ultrasound waves. | 2017-10-19 |
20170299576 | PEPTIDOMIMETIC MACROCYCLES - The present invention provides biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins. The invention additionally provides methods of identifying and making such improved polypeptides. | 2017-10-19 |
20170299577 | METHOD OF IDENTIFYING OR EVALUATING SYNERGISTIC COMBINATIONS OF ACTIVES AND COMPOSITIONS CONTAINING THE SAME - A method of identifying or evaluating synergistic combinations of actives such as skin-care actives that improve the metabolism of a cell and provides an advantage over using the actives alone. The method includes contacting cells with test agents, alone and in combination, and determining a response of the cells to the test agent(s), wherein the response corresponds to a change in a metabolic indicator associated with glycolysis and a change in a metabolic indicator associated with oxidative phosphylation. | 2017-10-19 |
20170299578 | MICROFLUIDIC ASPIRATOR AND METHODS OF MAKING AND USING THE SAME - Disclosed herein are devices that include a top chamber including at least one port, a bottom chamber including at least one inlet and at least one outlet, wherein the opening of the at least one inlet is smaller than the opening of the at least one outlet, and a membrane located between the top chamber and the bottom chamber, wherein the membrane is fluidly coupled with the top chamber and the bottom chamber. Also disclosed herein are systems including the disclosed devices. The systems include liquid in one or more of the chambers of the device. Methods of using the devices and systems include producing a vacuum by flowing a liquid through the bottom chamber of the system. Due to the difference in size of the inlet and outlet in the bottom chamber, a vacuum is produced in the top chamber. | 2017-10-19 |
20170299579 | VITELLINE MEMBRANE AS A MODEL OF THE BLOOD BRAIN BARRIER - The vitelline membrane of an egg is a novel, inexpensive and useful model of the human blood brain barrier (BBB). FD&C Blue #1, FD&C Red #40, FD&C Red #3, quinine and fluorescein do not cross the vitelline membrane and do not cross the human BBB. Ethanol, diethyl ether, 2-chloroprocaine and acetaminophen, cross the vitelline membrane and are known to cross the human BBB. Using the vitelline membrane, as model of the human BBB, may decrease the time and cost of discovering lead drugs for the treatment of central nervous system diseases. | 2017-10-19 |
20170299580 | POLYMER MICROPARTICLE FOR CARRYING PHYSIOLOGICALLY ACTIVE SUBSTANCE AND METHOD FOR PREPARING SAME - Provided are novel polymer particles for carrying a physiologically active substance and a method of preparing the same. The polymer particles for carrying a physiologically active substance can provide an analytical reagent, which has high analytical precision and sensitivity and can be stably prepared; can easily and precisely control the amount of functional groups carrying the physiologically active substance; can introduce, onto the surface of latex particles, a hydrophilic compound for inhibiting a nonspecific reaction; and can be prepared to have a narrow and uniform particle size distribution. The polymer particles for carrying a physiologically active substance are obtained by polymerizing a monomer, a radical polymerization initiator, and an emulsifier, and the emulsifier is an amphiphilic block polymer of the general formula (1): | 2017-10-19 |
20170299581 | ELECTROCHEMICAL TYROSINASE ENZYME IMMUNOASSAY BIOSENSOR AND SYSTEMS AND METHODS RELATED THERETO - Devices, assays and methods for detecting analytes in a sample are provided. Biosensor devices include a biosensor interface that includes enzyme-conjugated molecules, antibodies and an enzyme driven redox cycle coupled to an electrically conductive electrode for signal amplification. The biosensor devices are easily adaptable to a variety of assay formats, a variety of target analytes and provide real-time measurements combined with high sensitivity and high specificity for the analyte. | 2017-10-19 |
20170299582 | SOLID SUPPORT FOR IMPROVED DETECTION OF INTERACTION BETWEEN SPECIES - Disclosed is a solid support suitable for improving the detection of how different species interact with each other. The solid support has multiple defined areas divided by low dividers, and optionally independent containers divided by high dividers, each container having at least two defined areas. The solid support is typically used in measurements where the total amount of liquid is temporarily reduced during measurement. The solid support extends the possibilities of the measurement system. | 2017-10-19 |
20170299583 | System and Method for Pathogen Detection Using Multiple-Sized Polymer-Coated Beads within Lyotropic Chromonic Liquid Crystals - A novel detection system and method is presented, where a two-bead receptor method is used for capturing pathogens, with one type of bead being magnetic and having a size of 3 microns or smaller, and the other type being polymeric and having a size of 3 microns or larger. The first type is used to concentrate a pathogen; the latter is used to create a detectable signal. Fast sensitive detection is achieved by collecting the optical signal created by the distortion of a homeotropically aligned chromonic azo dye in the presence of captured pathogens. | 2017-10-19 |
20170299584 | SELF-SENSING ARRAY OF MICROCANTILEVERS FOR CHEMICAL DETECTION - The invention provides a chemical detection system for detecting at least one target chemical species, including a self-sensed cantilevered probe array having a plurality of self-sensed cantilevered probes, at least one chemical-sensitive coating material applied to at least one cantilevered probe in the cantilevered probe array, and an interface circuit that is coupled to the cantilevered probe array. At least one cantilevered probe in the cantilevered probe array exhibits a shifted cantilevered probe response when the cantilevered probe array is exposed to the target chemical species and the interface circuit actuates the cantilevered probe. A handheld chemical detection system and a method of operation are also disclosed. | 2017-10-19 |
20170299585 | COMPOSITIONS, KITS, AND METHODS FOR CELL SEPARATION - A cell-capturing substrate, methods of using the cell-capturing substrate that allow for label-free cell separation, and kits that incorporate the cell-capturing substrate. | 2017-10-19 |
20170299586 | METHOD OF DETECTING AN ANALYTE USING CHROMATOGRAPHIC ENRICHMENT - A device is provided. The device comprises a casing comprising an interior, a first opening, and a second opening; and a porous carrier comprising a sample-receiving zone and a target analyte-binding zone. The porous carrier defines a first fluid pathway that extends from the sample-receiving zone to the target analyte-binding zone. At least portion of the porous carrier is disposed in the interior of the casing. A second fluid pathway comprising a central axis extends through the casing from the first opening and the second opening, the second fluid pathway intersecting the porous carrier at the target analyte-binding zone. The central axis is oriented orthogonally with respect to the porous carrier. Methods of using the device to detect a target analyte are also provided. | 2017-10-19 |
20170299587 | LATERAL FLOW BLOTTING ASSAY - Methods, compositions, and kits for performing analyte detection in a lateral flow assay. | 2017-10-19 |
20170299588 | METHODS FOR SEPARATION AND IMMUNO-DETECTION OF BIOMOLECULES, AND APPARATUS RELATED THERETO - Disclosed are methods and apparatus for separation of biomolecules via two-dimensional gel electrophoresis, methods and apparatus for immunoblotting separated biomolecules, and methods for the use of biomolecules processed via the methods and apparatus of the present invention, including use in a clinical setting. The methods and apparatus for separation of biomolecules via two-dimensional gel comprises vertical agarose gel electrophoresis in the first dimension, and the electrophoresis of a novel non-denaturing 3-35% concave gradient polyacrylamide gel in the second dimension. This novel gel can be cast in a modified gel caster that can facilitate the pouring of multiple gels simultaneously. The methods and apparatus for immunoblotting are useful with any type of immunoblotting, including Western blot, Northern blot, and Southern blot analyses. These methods and apparatus provide safe, efficient and cost-effective immunoblots, while facilitating the reduction of exposure to toxic or radioactive materials, as well as the disposal of those materials. | 2017-10-19 |
20170299589 | Methods to Diagnose and Treat Multiple Sclerosis via Detection of Altered Protein Components of Serum - The methods disclosed herein include diagnosing a patient with MS, selecting a patient for further testing for MS, should the patient show elevated level of human IgG relative to an appropriate control. The methods also include differentiating subtypes of MS. The methods also include evaluating the efficacy of an MS drug or course of drug treatments, and/or treating MS. The methods include determining whether patients have elevated levels of IgG | 2017-10-19 |
20170299590 | METHODS AND COMPOSITIONS FOR SYSTEMIC LUPUS ERYTHEMATOSUS - The invention provides methods and compositions for the diagnosis, prognosis, and/or treatment response characterization of individuals suffering from systemic lupus erythematosus (SLE) using single cell network profiling. | 2017-10-19 |
20170299591 | EXOSOME-MEDIATED DIAGNOSIS OF HEPATITIS VIRUS INFECTIONS AND DISEASES - A method for diagnosing hepatitis virus infection or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers present on exosomes in a bodily fluid sample from the subject is disclosed. Also disclosed are a method for monitoring the course of a hepatitis virus infection or a hepatitis-diseases condition in a subject and a method for monitoring effectiveness of treatment to a subject with an anti-hepatitis virus agent based on hepatitis virus-associated biomarkers present on exosomes in bodily fluid samples from the subject, as well as a kit for diagnosing hepatitis virus infection and/or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers on exosomes in bodily fluid samples from the subject. | 2017-10-19 |
20170299592 | BIOMARKERS FOR ASSESSING BREAST CANCER - The present invention relates to a metabolic biomarker set for use in assessing breast cancer in a mammalian subject. In particular, the invention relates to a metabolic biomarker set for screening and/or diagnosing breast cancer, the metabolic biomarker set comprising at least (a) one amino acid selected from glutamine, glutamate and serine, and one lipid, or (b) glutamine and glutamate. Further, the invention relates to a metabolic biomarker set for prediction of therapeutic response to breast cancer neoadjuvant chemotherapy. Further, the invention relates to a metabolic biomarker set for assessing biochemical reflection of breast cancer tumor activity. Further, the invention relates to a metabolic biomarker set for subclassification between intrinsic breast cancer tumor subtypes. Moreover, the present invention relates to a method for assessing breast cancer, which comprises obtaining a biological sample, preferably blood, from a mammalian subject and measuring in the biological sample the amount and/or ratios of metabolites. By employing the specific biomarkers and the method according to the present invention it becomes possible to more properly and reliably assess breast cancer. | 2017-10-19 |
20170299593 | USE OF E-CADHERIN AND VIMENTIN FOR SELECTION OF TREATMENT RESPONSIVE PATIENTS - Methods and kits for the selection, evaluation, and/or treatment of a patient having cancer with an inhibitor of a glutamine-utilizing enzyme or a glutamine-depleting agent, by evaluating E-cadherin or vimentin expression are disclosed. | 2017-10-19 |
20170299594 | SIGNATURES AND PCDETERMINANTS ASSOCIATED WITH PROSTATE CANCER AND METHODS OF USE THEREOF - The present invention provides methods of detecting cancer using biomarkers. | 2017-10-19 |
20170299595 | METHOD OF ASSESSING DISEASE CONDITION OF CANCER - A method, system and computer-readable medium for assessing a disease condition of a cancer of a subject, including: receiving a blood sample from the subject; isolating a plurality of circulating tumor cells (CTCs) from the blood sample; measuring at least one of cell or cell nucleus sizes of each of the plurality of CTCs; determining a measured CTC size distribution of the plurality of CTCs based on the measuring; comparing the measured CTC size distribution to a reference CTC size distribution using a computer; and assigning the disease condition of the cancer of the subject based on the comparing. | 2017-10-19 |
20170299596 | MTOR KINASE MUTATIONS AND METHODS OF USE THEREOF - Certain embodiments of the invention provide a method of detecting the presence of a biomarker associated with resistance to an mTOR kinase inhibitor in a subject, comprising determining the presence of the biomarker in a physiological sample from the subject, wherein the sample comprises a nucleic acid. | 2017-10-19 |
20170299597 | COMBINED ANTICANCER DRUG SENSITIVITY-DETERMINING MARKER - To provide an anti-cancer agent sensitivity determination marker, which marker can determine whether or not the patient has a therapeutic response to the anti-cancer agent, and novel cancer therapeutic means employing the marker. | 2017-10-19 |
20170299598 | Methods and Monitoring of Treatment With A DLL4 Antagonist - Methods for treating diseases such as cancer comprising administering a DLL4 antagonist, either alone or in combination with other anti-cancer agents, and monitoring for cardiovascular side effects and/or toxicity. | 2017-10-19 |
20170299599 | PHOSPHORYLATION OF HISTONES AND USES THEREOF - Phosphorylation of histones was observed at certain tyrosine residues which have not been associated with epigenetic modification. These sites include H2B Tyr37, H4 Tyr88 and Tyr 51 and H3 Tyr99. Kinases responsible for the phosphorylation as well as downstream genes regulated by such phosphorylation were also identified. Antibodies that are specific to such phosphorylated histones have been generated, which are useful for detecting the phosphorylation and related events. With such findings, the present disclosure provides compositions and methods for disease diagnosis, prognosis and therapy selection, in particular for cancer, obesity and diabetes. | 2017-10-19 |
20170299600 | METHODS AND COMPOSITIONS FOR ASSESSING GERMLINE RISK OF CANCER - Heritable mutations in the BRCA1 and BRCA2 and other genes in the DNA double-strand break (DSB) repair pathway increase risk of breast, ovarian and other cancers. In response to DNA breaks, the proteins encoded by these genes bind to each other and are transported into the nucleus to form nuclear foci and initiate homologous recombination. Flow cytometry-based functional variant analyses (FVAs) were developed to determine whether variants in BRCA1 or other DSB repair genes disrupted the binding of BRCA1 to its protein partners, the phosphorylation of p53 or the transport of the BRCA1 complex to the nucleus in response to DNA damage. Each of these assays distinguished high-risk BRCA1 mutations from low-risk BRCA1 controls. Mutations in other DSB repair pathway genes produced molecular phenocopies with these assays. FVA assays may represent an adjunct to sequencing for categorizing VUS or may represent a stand-alone measure for assessing breast cancer risk. | 2017-10-19 |
20170299601 | RATIOMETRIC AND MULTIPLEXED SENSORS FROM SINGLE CHIRALITY CARBON NANOTUBES - A single chirality single walled carbon nanotubes (SWNT), and combinations thereof, can be used to detect trace levels of chemical compounds in vivo with high selectivity. | 2017-10-19 |
20170299602 | Biomimetic Chemical Sensors Using Nanoelectronic Readout of Olfactory Receptors - The present invention provides biomimetic sensor devices that utilize proteins—such G-protein coupled receptors—and are useful in high-sensitivity analysis of analyte-containing samples. These sensors may be used to determine the presence or concentration of one or more analytes in a sample. The invention also includes methods of fabricating the devices and methods of using the devices to assay samples. | 2017-10-19 |
20170299603 | METHOD AND APPARATUS FOR ANALYZING PROTEIN-PROTEIN INTERACTION ON SINGLE-MOLECULE LEVEL WITHIN THE CELLULAR ENVIRONMENT - A method of analyzing protein-protein interactions includes binding the first proteins to the substrate where the first proteins are tagged with the first markers which bind specifically to the biomolecules immobilized on the substrate or the first proteins bind specifically to the biomolecules immobilized on the substrate; incubating the substrate bound first proteins with cell lysate containing the second proteins which are tagged with second markers; analyzing the interactions between the first proteins and the second proteins in the cell lysate, and obtaining the first analytic value representing the kinetic picture of the interactions; incubating the substrate bound first proteins with cell lysate mixture of a cell lysate consisting of the second markers-tagged second proteins and another cell lysate comprising other proteins including unlabelled second proteins and obtaining the second analytic value; comparing and analyzing the first and the second analytic values. | 2017-10-19 |
20170299604 | SRM METHODS IN ALZHEIMER'S DISEASE AND NEUROLOGICAL DISEASE ASSAYS - Provided herein are methods for developing selected reaction monitoring mass spectrometry (LC-SRM-MS) assays. | 2017-10-19 |
20170299605 | SRM METHODS IN ALZHEIMER'S DISEASE AND NEUROLOGICAL DISEASE ASSAYS - Provided herein are methods for developing selected reaction monitoring mass spectrometry (LC-SRM-MS) assays. | 2017-10-19 |
20170299606 | IMMUNO-MALDI TO MEASURE AKT1 AND AKT2 PHOSPHORYLATION - This application relates to methods of quantifying AKT1 and AKT2 and determining AKT1 and AKT2 phosphorylation status. The disclosed methods allow for selection of cancer therapy. | 2017-10-19 |
20170299607 | Methods For Providing A Prognosis Of Pregnancy - The invention relates to a method of providing a prognosis for a pregnancy comprising subjecting a sample to direct mass spectral analysis, and comparing the spectra resulting from said analysis to spectra generated from samples obtained from 5 normal pregnancies. The invention describes subjecting a sample of maternal bodily fluid and/or fluids in which an embryo is cultured, or kept in, to direct matrix assisted laser desorption time of flight mass spectrometry and detection of spectral masses between 2,000 and 100,000 m/z. The changes in spectral masses, leading to changes in the profile of the spectra, are characteristic of disorders of fetal development and 10 pregnancy. | 2017-10-19 |
20170299608 | COMPOSITIONS AND METHODS FOR MODULATING BODY WEIGHT - The present disclosure provides a protein complex, including a three-dimensional structure of the protein complex, that plays a role in regulation of body weight. In addition, the protein complex and components thereof, including three-dimensional structures thereof, find use in identifying agents that can be used to control body weight. | 2017-10-19 |
20170299609 | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS WITH SK CHANNEL ACTIVATORS - Methods for treating amyotrophic lateral sclerosis (ALS). The methods include administering to a subject in need thereof a therapeutically effective amount of at least one small conductance calcium-activated potassium (SK) channel activator or a pharmaceutically acceptable salt or solvate thereof. Pharmaceutical compositions for the treatment of ALS, including a therapeutically effective amount of at least one SK channel activator, or a pharmaceutically acceptable salt or solvate thereof, and at least one excipient, adjuvant, or pharmaceutically acceptable carrier. | 2017-10-19 |
20170299610 | METHOD FOR DETECTING CELLS - The present invention relates to methods for detecting the chromatin state of a cell based on recording a super resolution image of nucleosome organization and correlating said imaged with size of nucleosomal clutches, nucleosomal density and/or number of nucleosomes per nucleosomal clutches. Additionally, the invention relates to a kit comprising a first antibody capable of specifically binding to a histone protein and a photoswitchable fluorophore linked-secondary antibody and the use of the kit of the invention for detecting the chromatin state of a cell and isolating a cell in an open chromatin state or in a closed chromatin state. The invention also relates to a device adapted to detect the chromatin state of a cell. | 2017-10-19 |
20170299611 | METHOD FOR EVALUATING ARTICULAR JOINT THERAPEUTICS - The invention provides a method for determining the efficacy of compositions used to treat articular joint conditions in mammals. The method includes measuring the change in levels of one or more cartilage degradation biomarkers in a mammal from before exercise and after exercise, then administering a composition used to treat articular joint conditions to the mammal, and measuring the change in levels of one or more cartilage degradation biomarkers in the mammal from before exercise and after exercise. | 2017-10-19 |
20170299612 | CARDIAC TROPONIN I DETECTION DURING PREGNANCY FOR CARDIOVASCULAR DISEASE IDENTIFICATION AND RISK ASSESSMENT - The present invention provides systems and methods for determining and reporting the cardiac troponin I (cTnI) concentration in a sample from a pregnant woman (in the first, second, or third trimester) by determining whether the sample (cTnI) concentration is higher than a 99 | 2017-10-19 |
20170299613 | Use of CD5 Antigen-Like as a Biomarker for Diabetic Nephropathy - Biomarkers for pre-Diabetes, Diabetes and/or a Diabetes related conditions, and methods of their use, including the biomarkers in Tables 1 and 2 such as peroxiredoxin-2, complement C1q subcomponent subunit B, sulfhydryl oxidase 1 and apolipoprotein A-IV. | 2017-10-19 |
20170299614 | Alzheimer's Disease - Variant forms of Amyloid-beta (Aβ) and kits comprising a variant Aβ are disclosed. The invention also provides uses of these kits and the Aβ variants in Aβ studies, for example in assays and methods for screening novel compounds for use in treating Alzheimer's Disease. | 2017-10-19 |
20170299615 | BIOMARKER FOR COGNITIVE DYSFUNCTION DISEASES, AND METHOD FOR DETECTION OF COGNITIVE DYSFUNCTION DISEASES USING THE BIOMARKER - The present invention aims to provide methods to detect cognitive impairment including mild cognitive impairment and Alzheimer disease by using a protein or its partial peptide that differs in presence or absence, or in quantity between non-cognitive impairment and patients with cognitive impairment and further aims to present biomarkers comprising said protein and said partial peptide to be used to detect cognitive impairment including Alzheimer disease or mild cognitive impairment. Specifically, a biomarker for diagnosis of psychiatry disease or cognitive impairment comprising protein fragment or peptide of not less than 5 amino acid residues arising from at least one protein or peptide selected from the group of proteins consisting of amino acid sequence expressed by SEQ ID NOS: 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 23, and 25 and selected from the group of partial peptide in these proteins consisting of amino acid sequence expressed by SEQ ID NOS: 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, and 27. And further aims to provide diagnostic method using these biomarker. | 2017-10-19 |
20170299616 | NOVEL BIOMARKERS FOR COGNITIVE IMPAIRMENT AND METHODS FOR DETECTING COGNITIVE IMPAIRMENT USING SUCH BIOMARKERS - The present invention aims to provide methods to detect cognitive impairment including mild cognitive impairment and Alzheimer disease by using a protein or its partial peptide that differs in presence or absence, or in quantity between non-cognitive impairment and patients with cognitive impairment and further aims to present biomarkers comprising said protein and said partial peptide to be used to detect cognitive impairment including Alzheimer disease or mild cognitive impairment. Specifically, a biomarker for diagnosis of psychiatry disease or cognitive impairment comprising protein fragment or peptide of not less than 5 amino acid residues arising from at least one protein or peptide selected from the group of proteins consisting of amino acid sequence expressed by SEQ ID NOS: 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 23, and 25 and selected from the group of partial peptide in these proteins consisting of amino acid sequence expressed by SEQ ID NOS: 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, and 27. And further aims to provide diagnostic method using these biomarker. | 2017-10-19 |
20170299617 | METHODS AND COMPOSITIONS RELATED TO LIPOPROTEINS IN BLOOD SAMPLES - Methods and compositions related to lipoproteins reactions are provided. Particularly, quantitation of lipoprotein subgroup particle numbers may be used to detect lipoprotein's response to oxidation conditions and incubation conditions. In further aspects, ultracentrifugation may be improved to analyze the lipoprotein profiles. Embodiments are directed to methods for generating a oxidation susceptibility measure for serum lipoproteins. In certain aspects a first portion of a serum sample is used to generate a base lipid particle profile (LPP) and a second portion of the serum sample is used to generate an oxidized lipid particle profile. | 2017-10-19 |
20170299618 | ANTIBODIES TO RISPERIDONE AND USE THEREOF - Disclosed is an antibody which binds to risperidone, which can be used to detect risperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of risperidone, including multiplex detection of aripiprazole, quetiapine, olanzapine, and risperidone in a single lateral flow assay device. | 2017-10-19 |
20170299619 | CONSUMABLE MANIPULATION FOR THE PURPOSE OF LIQUID HANDLING - A method and device to perform liquid handling by means of manipulation and transportation of consumables, instead of manipulation and transportation of a liquid handling head, among static or quasi-static liquid handling heads. A quasi-static liquid handling head (or pipette) that doesn't move between the aspiration and dispensing steps. | 2017-10-19 |
20170299620 | ONLINE MEASURING METHOD OF PARTICLE VELOCITY IN MULTIPHASE SYSTEM - The present invention provides an online measuring method of particle (such as bubbles, droplets and solid particles) velocity in multiphase reactor. The method based on an online multiphase measuring instrument includes the following steps: (1) the online multiphase measuring instrument is placed into the multiphase reactor, and then a particle image produced by two or more exposures are obtained; (2) the actual size of individual pixel in the particle image is determined; (3) valid particles are determined in the depth of field; (4) then the centroid coordinates are conversed to the actual length of the coordinates (x | 2017-10-19 |
20170299621 | DETECTION AND WIRELESS TRANSMISSION OF WHEEL ROTATION DIRECTION - Wireless transmission of wheel rotation direction is disclosed. A disclosed apparatus includes a tone ring exhibiting a rotational asymmetry and a detector to measure a rotational direction of a wheel of a vehicle based on the rotational asymmetry and to measure a rotational speed of the wheel, where the detector or the tone ring is operatively coupled to the wheel. The disclosed apparatus also includes a wireless transmitter to transmit the rotational direction and the rotational speed to a receiver proximate or within an engine compartment of the vehicle. | 2017-10-19 |
20170299622 | SENSOR ELEMENT FOR THERMAL ANEMOMETRY - A sensor element for thermal anemometry includes a semiconductor substrate and a thin-film diaphragm attached to the semiconductor substrate and having a front side and a rear side. A resistive heating element and a temperature-dependent resistor are attached to the front side of the thin-film diaphragm. In the area of the rear side of the thin-film diaphragm, the semiconductor substrate has a first recess. A silicon layer including a recess which merges with the first recess of the semiconductor substrate is located between the thin-film diaphragm and the semiconductor substrate. | 2017-10-19 |
20170299623 | INERTIAL FORCE SENSOR - An inertial force sensor includes: an acceleration detection element; a temperature sensor that detects an ambient temperature of the acceleration detection element; a bridge circuit that processes an output signal from the acceleration detection element; an AD converter that converts an analog signal output from the bridge circuit into a digital signal, and outputs the digital signal; a calculation circuit that performs calculation on the output signal from the AD converter; and a storage that stores correction data for correcting a variation in the output signal from the AD converter due to a temperature change. The correction data are coefficients of a formula expressed by a calibration curve that is a quadratic or higher-degree curve, and the storage stores, as the correction data, the coefficients of the calibration curve of each of a plurality of patterns that differ between a predetermined temperature or more and less than the predetermined temperature. | 2017-10-19 |
20170299624 | MULTIPLE METER DETECTION AND PROCESSING USING MOTION DATA - Systems and methods are disclosed for identifying portable devices carried by the same person. An example method includes receiving media exposure data from one of a plurality of portable computing devices. Receiving segmented accelerometer data from the plurality of portable computing devices. Forming accelerometer classification data for the plurality of portable computing devices based on features extracted from the segmented accelerometer data. Comparing the accelerometer classification data for the first portable computing device to accelerometer classification data for the plurality of portable computing devices, to determine if the accelerometer classification data for the first portable computing device is sufficiently similar to a second portable computing devices. The example method further includes identifying the first and second portable computing device as being physically carried by a same person when the comparison determines that the accelerometer classification data for the first portable computing device is sufficiently similar to the second computing devices. | 2017-10-19 |
20170299625 | WHEEL SENSOR INTERFACE APPARATUS - A wheel sensor interface apparatus may include: a wheel sensor interface unit configured to supply power to a wheel sensor of a vehicle, or sense an output current of the wheel sensor and transmit the sensed current to a microprocessor unit of the vehicle; and an over-current detection unit including: a reference current generation unit configured to generate a reference current using a voltage across a resistor through which the output current flows; and a voltage level decision unit configured to decide a voltage level according to the reference current. The over-current detection unit may determine whether the output current is an over-current, according to the voltage level. | 2017-10-19 |
20170299626 | System and Method for Performing a Test on a Pitot Probe Heating Element - A system for testing a pitot probe heating element includes first and second probes, measuring signals selected from a first signal representing a differential electric current between supply and return wires of the heating element, a second signal representing a residual voltage with respect to ground in the heating element, and a third signal representing ambient electric fields with respect to ground in the heating element; a signal acquisition component that selectively and sequentially applies a test voltage to the heating element to generate the selected signals and receives the selected signals measured by the first and second probes; a signal processing component that receives the selected ones of the first, second, and third signals, processes them, and extracts measurements from the data to generate results indicative of a condition of the heating element; a device control component that generates a display; and a display component. | 2017-10-19 |
20170299627 | METHOD FOR DETERMINING ANTIFOULING ABILITY OF A MATERIAL SURFACE AND DETERMINING DEVICE FOR DETERMINING ANTIFOULING ABILITY OF MATERIAL SURFACE - A method for determining antifouling ability of a material surface includes: (a) providing a determining device, wherein the determining device includes: a probe, wherein the probe includes a micro particle or a micro particle and a pollutant fixed on a surface of the micro particle; and a determining unit with a spring characteristic structure, wherein the probe is fixed at one end of the spring characteristic structure; (b) contacting the probe with a material surface-to-be-determined to make the micro particle itself or the pollutant on the surface of the micro particle adhere to the material surface-to-be-determined; (c) deforming the spring characteristic structure until the probe departs from the material surface-to-be-determined to recover the spring characteristic structure, and determining the level of the deformation; (d) determining the adhesion value of the probe to the material surface-to-be-determined using the deformation; and (e) determining the antifouling ability of the material surface. | 2017-10-19 |
20170299628 | QUANTITATIVE MEASUREMENTS USING MULTIPLE FREQUENCY ATOMIC FORCE MICROSCOPY - The imaging mode presented here combines the features and benefits of amplitude modulated (AM) atomic force microscopy (AFM), sometimes called AC mode AFM, with frequency modulated (FM) AFM. In AM-FM imaging, the topographic feedback from the first resonant drive frequency operates in AM mode while the second resonant drive frequency operates in FM mode and is adjusted to keep the phase at 90 degrees, on resonance. With this approach, frequency feedback on the second resonant mode and topographic feedback on the first are decoupled, allowing much more stable, robust operation. | 2017-10-19 |
20170299629 | PROBE CARD - A probe card includes a wiring board, a top cover, a retractable structure and a probe. The top cover couples with the wiring board and has an air inlet. The retractable structure connects with the top cover and includes a first and a second rings. The first ring has vent holes. A top surface of the first ring and a first bottom surface of the top cover define a homogenized space communicating with the air inlet and the vent holes. The second ring couples with the first ring and has jet holes communicating with the vent holes. Outlets of the jet holes locate on a second bottom surface of the second ring. A first inner sidewall of the first ring and a second inner sidewall of the second ring define a pressure space. The probe connects with the wiring board and extends to the pressure space. | 2017-10-19 |