42nd week of 2021 patent applcation highlights part 39 |
Patent application number | Title | Published |
20210325358 | DETECTION OF GASES AND VAPORS BY PATTERNED NANOPARTICLE LIQUID CRYSTAL ALIGNMENT - A sensor for detecting non-hazardous and especially hazardous gases and/or vapors comprises a liquid crystal cell generally having a standard substrate and a conductive electrode layer thereon. An alignment layer is desirably located on the electrode layer and contains one or more types of metal nanoparticles that cover at least a portion of the alignment layer. The nanoparticles contain at least one type of ligand thereon that is capable of sensing a specific type of non-hazardous or hazardous gas. The sensor is very sensitive and can detect the gases or vapors contained within air, or the like, up to 1 part per million. | 2021-10-21 |
20210325359 | METHOD OF IDENTIFYING A SOURCE COMPONENT OF PARTICULATE DEBRIS IN AN AIRCRAFT ENGINE - The method can include analyzing the composition of the particulate metal debris, including ascertaining a presence of at least one main alloy element and a presence or absence of at least one signature alloy element in the particulate debris; establishing a correlation between the particulate metal debris and a set of components, including matching the ascertained presence of the at least one main alloy element to a family of alloys from which the components of the set, including the source component, are made; and determining the source component amongst the components of the set, including matching the ascertained presence or absence of the at least one signature alloy element to an alloy composition of the source component. | 2021-10-21 |
20210325360 | METHODS FOR DETERMINING AIR RELEASE PERFORMANCE OF LUBRICATING OILS - Provided is a method for determining air release performance of a lubricating oil. The method involves determining air release time of the lubricating oil in accordance with ASTM D3427 at a designated temperature; determining surface tension of the lubricating oil at the temperature used in ASTM D3427; determining kinematic viscosity of the lubricating oil in accordance with ASTM D445 at the temperature used in ASTM 3427; and utilizing the surface tension, ASTM D3427 air release time, and ASTM D445 kinematic viscosity to determine air release performance of the lubricating oil. Surface tension is correlated with ASTM D3427 air release time at an ASTM D445 kinematic viscosity of at least about 30 cSt. The method has higher measurement sensitivity and reproducibility/repeatability than ASTM D3427. | 2021-10-21 |
20210325361 | System for Indicating Content within a Fluid Container - A system for indicating content within a fluid container provides an improved fuel container for mixed fuel, which indicates its contents to a user. The system communicates whether there is oil, gas, a mixture of the two, or nothing inside the container. When the system is filled with gas only, the color of the can will change to, or otherwise remain, a first color. Similarly, oil alone would be indicated by a unique color. When a user combines oil and gas, the system changes to a new color to let the user know that oil is indeed inside the receptacle of the apparatus. Alternatively, the system may provide a nozzle equipped with the same color-indicating capabilities as the fuel receptacle embodiment. For example, when oil is mixed with gas inside the system, the nozzle may turn blue to ensure that a user is aware of the change of contents. | 2021-10-21 |
20210325362 | METHOD OF IDENTIFYING A SOURCE COMPONENT OF PARTICULATE DEBRIS IN AN AIRCRAFT ENGINE - The gas turbine engine can have a set of components, the components of the set all being made of material compositions of the same type having a common at least one main material element, the material compositions having distinct signatures in the form of a varying trace amount of one or more signature element, the distinct signatures varying from one component of the set to another. | 2021-10-21 |
20210325363 | METHOD FOR DETERMINING DEGREE OF SLUDGE GENERATION IN OIL - A method for determining the degree of sludge generation in oil includes: a deteriorated oil generating step ST | 2021-10-21 |
20210325364 | METHOD OF ANALYZING THE BOND STRENGTH OF CEMENT AND FORMATION WITH DISCRETE IMAGE ANALYSIS - A method of analyzing a composite plug includes creating a composite plug, where the composite plug includes a formation layer, a cement layer, and an interface region between them, and the cement extends into the formation sample in the interface region. The method further includes imaging the composite plug to gather a series of discrete images, where each discrete image in the series depicts a cross section of the composite plug and the discrete images are taken at set increments throughout a depth of the composite plug. The method further includes analyzing each discrete image in the series of discrete images to determine a porosity measurement of each discrete image, determine a first and second boundary of the interface region from the porosity measurement of each discrete image, and determine a depth of the interface region by a number of discrete images between the first boundary and the second boundary. | 2021-10-21 |
20210325365 | BIOLOGICAL NANOPORES HAVING TUNABLE PORE DIAMETERS AND USES THEREOF AS ANALYTICAL TOOLS - The invention relates to the field of nanopores, in particular to engineered Fragaceatoxin C (FraC) nanopores and their application in analyzing biopolymers and other (biological) compounds, such as single-molecule (protein) sequencing. Provided is a system comprising oligomeric FraC nanopores comprised in a lipid bilayer, wherein the sum of the nanopore fraction in the heptameric (Type II) state and the nanopore fraction in the hexameric (Type III) state represents at least 60% of the total number of FraC nanopores. | 2021-10-21 |
20210325366 | REPLACEABLE GROUND ELECTRODE FOR ELECTROPHYSIOLOGY, ELECTRODE REJUVENATING APPARATUS, AND RELATED METHODS AND SYSTEMS - A plenum assembly configured for electrophysiology assays, such as patch clamp techniques, includes one or more ground electrode assemblies. The ground electrode assemblies are individually removable from a plenum base of the plenum assembly in a non-destructive manner, and may be reinstalled in the plenum base in a manner that reestablishes electrical contact with ground circuitry without requiring soldering or other additional steps. A rejuvenating apparatus is provided for rejuvenating one or more ground electrode assemblies removed from the plenum base. | 2021-10-21 |
20210325367 | Controlled Exposure to Pathogens for Generating Immunity - A method generates a natural immunity to a pathogen in the absence of a vaccine. The process draws a blood sample, exposes the blood sample to a pathogen outside of a living organism, and measures the antibody type, level, and a pathogen level in the exposed blood sample. The method injects the blood sample exposed to the pathogen into the source of the blood sample when one or more antibody types are detected at a predetermined level and the pathogen level is below a predetermined level. | 2021-10-21 |
20210325368 | METHODS DETERMINING AND TREATING CELLULAR RESISTANCE TO ADP-RIBOSYLATING TOXIN - The present invention is based in part on the identification of DPH1 and other members of the diphthamide synthesis pathway as biomarkers of resistance to an ADP-ribosylating toxin in a cell, and methods for identification, assessment, and treatment of a condition that is resistant to an ADP-ribosylating toxin. | 2021-10-21 |
20210325369 | PREDICTIVE BIOMARKERS FOR AN IMMUNE RESPONSE - Biomarkers and uses thereof, as well as methods for using same for identifying vaccine recipients who will respond to a single dose of vaccine. In addition, an integration model for identifying biomarkers is also provided, such that the biomarkers form a network of signatures associated with a vaccine responder. | 2021-10-21 |
20210325371 | APPARATUS, SYSTEMS, AND METHODS FOR QUANTIFYING INFECTIOUS AGENTS - Various methods, devices, and systems for determining the concentration of infectious agent in a target sample are disclosed herein. In one embodiment, a method for determining the concentration of an infectious agent of an unknown strain can include diluting aliquots of a target sample comprising the infectious agent by different dilution factors to yield diluted samples. The method can also include determining the time it takes a solution characteristic of each of the diluted samples to undertake a predetermined threshold change. The method can also include determining the concentration of the infectious agent of the unknown strain by taking into account the different dilution factors, the monitored times, and certain curve fitting parameters calculated from predetermined calibration curves generated for infectious agents of different known strains. | 2021-10-21 |
20210325372 | METHOD TO ASSESS CAR FUNCTIONALITY - The present invention relates a method for assessing the functionality of a chimeric antigen receptors (CAR) expressing cell. More specifically, this method is based on a trogocytosis process which involves membrane transfer between antigen expressing target cells and antigen specific immune cells. | 2021-10-21 |
20210325373 | PERFORMING OPTICAL MEASUREMENTS ON A SAMPLE - Apparatus and methods are described including measuring hematocrit within a blood sample, by performing a first measurement on a first portion of the blood sample. Mean corpuscular volume in the blood sample is measured, by performing a second measurement on a second portion of the blood sample, the second portion being diluted with respect to the first portion. A red blood cell count per unit volume within the blood sample is determined by dividing the hematocrit measured within the first portion by the mean corpuscular volume measured within the second portion. Other applications are also described. | 2021-10-21 |
20210325374 | UNIVERSAL MARKER FOR WATER QUALITY ASSESSMENT - An apparatus for detecting, in a liquid such as water, concentrations of chemicals that exceed the maximum allowable concentrations, includes a substrate, and a plurality of test strips disposed on the substrate, each test strip having an indicator that reacts to a concentration of a chemical that exceeds the maximum allowable concentration for that chemical. The substrate includes a dissolvable coating covering the test strips to isolate the test strips from air prior to immersion of the substrate in the liquid, and to dissolve when immersed in the liquid to expose the indicator of each test strip to the liquid. | 2021-10-21 |
20210325375 | MULTISIGNAL REAGENTS FOR LABELING ANALYTES - Provided is a multisignal labeling reagent comprising a first polymer covalently bound to (a) a reactive group or a first member of a first binding pair, and (b) more than one digoxigenin molecule. | 2021-10-21 |
20210325376 | POLYMERS AND CONJUGATES COMPRISING THE SAME - Polymers and conjugates comprising polymers are disclosed herein. In some embodiments, the conjugates disclosed are suitable for use as detection probes in immunohistochemical assays, including multiplex immunohistochemical assays. | 2021-10-21 |
20210325377 | METHOD FOR MEASUREMENT OF TOTAL PROTEIN CONTENT AND DETECTION OF PROTEIN VIA IMMUNOASSAY IN A MICROFLUIDIC DEVICE - Some embodiments described herein relate to systems and methods operable to combine immunoassay and Total Protein techniques in a single sample run. Some embodiments described herein allow for multiple sequential immunoassays to be performed in the same microfluidic device. Some embodiments described herein relate to stripping reagents operable to remove primary antibodies associated with immunoassays. Such stripping reagents can allow for additional immunoassays and/or Total Protein assays to be performed on the same sample. | 2021-10-21 |
20210325378 | METHODS AND COMPOSITIONS FOR REMOVING BIOTIN INTERFERENCE FROM ASSAYS USING CYCLODEXTRIN TRAPS - The present invention relates to methods and compositions to remove or reduce biotin interference from certain assays. | 2021-10-21 |
20210325379 | SINGLE-MOLECULE ELECTRONIC SEQUENCE DETECTOR AND METHODS OF USE - The present disclosure provides devices, systems, and methods related to single molecule detection. In particular, the present disclosure provides devices and methods for sequence-specific detection of a nucleic acid target using current fluctuations as a readout for protein binding to the nucleic acid target. As described herein, certain aspects of the bioelectronic devices and method can be used to detect and identify any nucleic acid target for the purpose of diagnosis and/or treatment. | 2021-10-21 |
20210325380 | DISEASE DIAGNOSTICS USING A MULTI-CONFIGURABLE SENSING ARRAY - A sensor device includes a porous substrate layer and an array of sensors to accept a sample. The array of sensors includes a plurality of sensors, each of the plurality of sensors includes respective semiconducting nanostructures with a respective capture reagent coupled to the semiconducting nanostructures that selectively binds to a respective target analyte in the sample. The array of sensors includes a first subset of sensors with first capture reagents to bind to biomarkers characteristic of a particular disease and a second subset of sensors with second capture reagents to bind to one of cytokines, chemokines, enzymes, metabolites, or antibodies present in the sample. | 2021-10-21 |
20210325381 | Using Exhaled Breath Condensate for Testing for a Biomarker of COVID-19 - An apparatus for detecting a biomarker comprises a droplet harvesting structure for converting breath vapor to a fluid droplet for forming a fluid sample and a testing system having a biomarker testing zone for receiving the fluid sample and detecting a biomarker. The droplet harvesting structure may include at least one of a hydrophobic field for receiving the breath vapor and forming the fluid droplet from the received breath vapor and hydrophilic channels for receiving the fluid droplet and channeling the fluid droplet towards the testing system. A fluid dam member may be provided disposed between the droplet harvesting structure and the biomarker testing zone. | 2021-10-21 |
20210325382 | Using Exhaled Breath Condensate, Aerosols and Gases for Detecting Biomarkers - An apparatus for detecting a biomarker includes a particulate capturing structure for receiving and capturing exhaled breath aerosol (EBA) particulate from airway linings of a user, the particulate capturing structure having an aerosol particulate testing system for receiving the captured particulate and detecting a first biomarker, wherein the aerosol particulate testing system includes a dissolvable EBA sample collector film for capturing EBA particulate. The apparatus may include a droplet harvesting structure for converting breath vapor to a fluid droplet for forming a fluid sample and a testing system having a biomarker testing zone for receiving the fluid sample and detecting a biomarker. | 2021-10-21 |
20210325383 | LATERAL FLOW ASSAY FOR DETECTING MULTIPLE PROTEINS OF A PATHOGEN - A lateral flow assay device includes a test strip that is configured to receive a sample fluid and detect a presence of antibodies to one or more of a plurality of proteins of the target pathogen. The lateral flow assay device includes a conjugate pad and a membrane. The conjugate pad contains a plurality of the proteins of the target pathogen, each conjugated with a label. If the sample fluid contains antibodies that are specific to the target pathogen through any of the target pathogen's proteins, a binding takes place between those antibodies and the corresponding tagged protein. The membrane may include a plurality of test lines. Each test line may contain the immobilized binding reagent to one antibody class, resulting in the concentration of all the molecules of that antibody class on the test line. | 2021-10-21 |
20210325384 | IMMUNOCHROMATOGRAPHIC DEVICE FOR EXTRACTING AND MEASURING SUGAR CHAIN ANTIGEN - It is intended to provide a method and an immunochromatographic device, which are capable of measurement with sufficient sensitivity by performing a nitrous acid extraction treatment over a sufficient period of time in an immunochromatography method of extracting and measuring a sugar chain antigen by nitrous acid extraction on an immunochromatographic test piece. The present invention provides an immunochromatographic device comprising an immunochromatographic test piece for extracting and measuring a sugar chain antigen in a specimen, and a container which stores the test piece, the immunochromatographic device having a specimen addition port in a sample pad of the test piece, the immunochromatographic test piece comprising: a sample pad to which a specimen mixed with nitrite or an acid solution is added; a label region comprising a labeled antibody obtained by labeling an antibody against the sugar chain antigen; and a detection region on which the antibody against the sugar chain antigen is immobilized, wherein an antibody-sugar chain antigen-labeled antibody complex is formed in the detection region to measure the sugar chain antigen, and the immunochromatographic test piece having a region impregnated with a neutralizing reagent upstream of the label region, and further having a region impregnated with a solid acid reagent when the specimen mixed with the nitrite is used, or a region impregnated with nitrite when the specimen mixed with the acid solution is used, upstream of the region impregnated with the neutralizing reagent, wherein the immunochromatographic device (i) has a wide specimen addition port for promoting the extraction of the sugar chain antigen with the nitrite and the solid acid reagent by retaining an added specimen sample solution and supplying the specimen sample solution in a short time to the region impregnated with the solid acid reagent or the nitrite, and (ii) has no space between the addition port and the sample pad so as to prevent the sample from escaping from the addition port. | 2021-10-21 |
20210325385 | PH-GRADIENT SPR-BASED BINDING ASSAY - Herein is reported a method for determining the dissociation rate constant k | 2021-10-21 |
20210325386 | Microfluidic Devices and Methods for Rapid Detection of Pathogens and Other Analytes - The invention provides devices and methods for detecting viruses, bacteria, and other analytes of interest in a fluid sample. The fluid sample flows through a first microfluidic channel to a nanoporous or microporous membrane on which are disposed ligands, such as antibodies, specific for the analyte. If the analyte of interest is captured by the ligand, it clogs the pores of the membrane, preventing the fluid sample from passing through the membrane and diverting the fluid into a second channel. Detecting movement of the fluid sample in the second channel signals the presence of the analyte in the fluid sample, while failure of the fluid sample to move in the second channel signals absence of the analyte in the fluid sample. | 2021-10-21 |
20210325387 | CELL ATLAS OF THE HEALTHY AND ULCERATIVE COLITIS HUMAN COLON - The present invention provides for a human cell atlas of the colon from healthy and diseased subjects. The atlas was obtained by single sequencing of about 117,000 cells. The present invention discloses novel markers for cell types. Moreover, genes associated with disease are identified in the colon and colon specific cell types. The invention provides for diagnostic assays based on gene markers and cell composition, as well as target cell types that express genes associated with disease. Finally, disclosed are novel cell types and methods of quantitating, detecting and isolating the cell types. | 2021-10-21 |
20210325388 | LATERAL FLOW DETECTION DEVICE FOR DETECTING A CORONAVIRUS BY IMMUNOASSAY - The invention provides a lateral flow detection device for detecting a coronavirus by immunoassay, wherein the detection device comprises two lateral flow test strips, a test strip 1 is used to test an antibody to a N full-length protein and/or a S full-length protein, while a test strip 2 is used to test an antibody to a S-RBD site protein, and a combination of the two test strips is used to test IgG and IgM antibodies to novel coronavirus, which further improves a detection rate of serological antibodies and effectively reduces a possibility of missing detection and wrong detection, thereby avoiding any missing detection. | 2021-10-21 |
20210325389 | System and Method for Obtaining Post-Infection Clearance - A system for obtaining clearance comprises a mechanism to identify the user and generate an identification signal; an analytical toilet comprising a bowl to receive excreta from the user; an analyzer configured to analyze the sample to detect one or more antibodies in a sample of the excreta or sputum and to generate an analysis signal; a processor configured to receive the identification signal and the analysis signal; determine therefrom the status of the user with respect to the one or more antibodies; and transmit a report to an authority, the report comprising the identity and the status of the user with respect to the antibodies detected. A method for obtaining clearance comprises linking a user to an analytical toilet; receiving a sample of excreta from the user in the analytical toilet; analyzing the sample of excreta in an analytical toilet to detect one or more antibodies; processing results from the analytical toilet and determining the status of the user with respect to the antibodies detected; submitting the identity and the status of the user with respect to the antibodies detected to an authority. | 2021-10-21 |
20210325390 | Virus detection - The invention includes methods and kits for the detection of a virus that may be in a sample. In embodiments, the invention includes a method of detecting a virus in a sample by forming a reaction mixture exposing an aliquot of the sample purportedly containing a virus to an immobilized receptor. A soluble receptor including a detectable label is added to the reaction mixture. A washing step washes the immobilized receptor, and the detectable label is detected. | 2021-10-21 |
20210325391 | METHOD FOR EVALUATION THE PRESENCE OF A VIRAL RESERVOIR - A method for the evaluation of the efficacy of a drug aiming to eradicate a cellular reservoir of mammalian cells infected with a mammalian immunodeficiency virus, the method including: a) quantifying, the presence of lymphocyte cells expressing a CD89 differentiation marker on their surface; and b) concluding that the drug is efficient to eradicate the cellular reservoir of mammalian cells infected with the mammalian immunodeficiency virus when lymphocyte cells expressing a CD89 differentiation marker are absent. | 2021-10-21 |
20210325392 | Activated GTPase-Based Assays and Kits for the Diagnosis of Sepsis and Other Infections - In one embodiment, the invention provides a method of diagnosing sepsis or a virus-related infection (often a viral hemorrhagic fever infection) in a subject by detecting and measuring the level of a set of sepsis and virus infection-associated-GTPase biomarkers in a sample obtained from the subject using multiplexed flow cytometry. Related kits are also provided. In a preferred embodiment, the invention provides point of care diagnostic methods for determining an early stage sepsis or the severity of a virus infection, especially in a hospital or other setting. | 2021-10-21 |
20210325393 | DETECTION OF LYME DISEASE - The disclosure, in some aspects, provides antigen-specific amino acid sequences for | 2021-10-21 |
20210325394 | METHOD FOR PROVIDING INFORMATION ON THERAPEUTIC REACTION OF CANCER IMMUNOTHERAPY AND KIT USING SAME - Provided in the present disclosure are a method for providing information on a therapeutic reaction of cancer immunotherapy and a kit using same for providing information, the method comprising the steps of: measuring respective expression levels of PD-L1 and PVR in a biological sample isolated from a subject; and evaluating the therapeutic reaction of cancer immunotherapy for the subject on the basis of the measured expression levels of PD-L1 and PVR. | 2021-10-21 |
20210325395 | METHOD, ARRAY AND USE THEREOF - The present invention relates to a method for determining the locality and/or presence of pancreatic cancer in an individual comprising or consisting of the steps of: (a) providing a sample to be tested from the individual, and (b) determining a biomarker signature of the test sample by measuring the expression in the test sample of one or more biomarkers selected from the group defined in Table A, wherein the expression in the test sample of one or more biomarkers selected from the group defined in Table A is indicative of the locality and/or presence of pancreatic cancer in the individual. The invention also comprises arrays and kits of parts for use in the method of the invention. | 2021-10-21 |
20210325396 | IDENTIFICATION OF PROTEIN ASSOCIATED WITH HEPATOCELLULAR CARCINOMA, GLIOBLASTOMA AND LUNG CANCER - The present invention provides methods and compositions for screening, diagnosis and prognosis of HCC, glioblastoma and lung cancer, for monitoring the effectiveness of HCC, glioblastoma and lung cancer treatment, and for drug development. | 2021-10-21 |
20210325397 | DIGITAL ANALYSIS OF MOLECULAR ANALYTES USING ELECTRICAL METHODS - Electrical detection methods are used to identify and further characterize single-molecule target analytes such as proteins and nucleic acids. A composition including a probe region and a tail region is contacted with a target analyte. The probe region specifically binds to the target analyte. The tail region is coupled to the probe region, and includes a nucleic acid template for polynucleotide synthesis. When conditions are such that polynucleotide synthesis occurs along the tail region, one hydrogen ion is released for every nucleotide that is incorporated into the tail region. A transistor such as an ISFET detects and measures changes in ion concentration, and these measurements can be used to identify the tail region and thus characterize the corresponding target analyte. | 2021-10-21 |
20210325398 | TARGETED SIALIC ACID LABELING COMPOUNDS, METHODS, AND USES THEREOF - Described herein are compounds, compositions, and reagents capable of labeling a biomolecule. In some embodiments, the compounds, compositions, and reagents allow for labeling to occur using a bioorthagonal reaction outside of a living cell and without a glycosyltransferase enzyme. Also described herein are methods of using the compounds compositions and reagents described herein. | 2021-10-21 |
20210325399 | NEAR-INFRARED FLUORESCENT NANOPROBE - A fluorescent probe having a capsule of nanometric size and an aggregate of fluorogenic molecules coupled to the capsule is provided. The aggregate emits a fluorescent signal at one or more wavelengths within the fluorescence spectral range when the probe is illuminated by an excitation light beam at one or more wavelengths within the excitation spectral range. Preferably, the fluorescent spectral range is in the near-infrared region of the spectrum. In some embodiments, the capsule is a boron nitride (BN) nanotube and the aggregate comprise 3,6-Bis[2,2]bithiophenyl-5-yl-2,5-di-n-octylpyrrolo[3,4-c]pyrrole-1,4-dione as fluorogenic molecules. In some embodiments, the 3,6-Bis[2,2]bithiophenyl-5-yl-2,5-di-n-octylpyrrolo[3,4-c]pyrrole-1,4-dione fluorogenic molecules are in a J-aggregation state. | 2021-10-21 |
20210325400 | PREECLAMPSIA DIAGNOSTIC DEVICES, SYSTEMS AND METHODS - Provided are diagnostic and/or screening tests, assays and devices for preeclampsia (PE). The diagnostic and/or screening tests, assays and devices include test antibodies for activin A and/or inhibin A. The PE diagnostic and/or screening tests, assays and devices are capable of detecting activin A and/or inhibin A in a sample at a concentration of less than about 60 pg/m L. Corresponding methods of diagnosing and/or screening for PE are provided. | 2021-10-21 |
20210325401 | METHOD FOR MEASUREMENT OF TOTAL PROTEIN CONTENT AND DETECTION OF PROTEIN VIA IMMUNOASSAY IN A MICROFLUIDIC DEVICE - Some embodiments described herein relate to systems and methods operable to combine immunoassay and Total Protein techniques in a single sample run. Some embodiments described herein allow for multiple sequential immunoassays to be performed in the same microfluidic device. Some embodiments described herein relate to stripping reagents operable to remove primary antibodies associated with immunoassays. Such stripping reagents can allow for additional immunoassays and/or Total Protein assays to be performed on the same sample. | 2021-10-21 |
20210325402 | DETECTION OF MEMBRANE PROTEINS BY MASS SPECTROMETRY - A method of detecting a membrane protein by mass spectrometry comprises: (a) providing a solution comprising a native membrane vesicle having a lipid bilayer to which said membrane protein is attached; (b) sonicating the vesicle in the presence of a mass spectrometry-compatible buffer; (c) providing a mass spectrometer comprising a nanoelectrospray ionisation source, a mass analyser and a detector; (d) vaporising the sonicated solution using the nanoelectrospray ionisation source under conditions such that the membrane protein is released from the vesicle; (e) ionising the membrane protein; (f) resolving the ionised membrane protein using the mass analyser; and (g) detecting the resolved membrane protein using the detector. Also provided are solutions comprising sonicated vesicles for use in mass spectrometry methods. | 2021-10-21 |
20210325403 | CELLULAR ASSAYS WITH A MOLECULAR ENDPOINT MEASURED BY SAMDI MASS SPECTROMETRY - The disclosure provides a cell-based, label-free assay compatible with high-throughput screening (HTS) that can report quantitatively on enzyme activities by measuring mass changes of substrates with MALDI-mass spectrometry. | 2021-10-21 |
20210325404 | METHODS FOR PERFORMING EX VIVO DIAGNOSTIC TESTS FOR THE PRESENCE OF A PROLIFERATION-INDUCING LIGAND (APRIL) IN A HUMAN SAMPLE - The invention relates to a method for obtaining APRIL-binding peptides. With this method APRIL-binding peptides may be obtained and/or selected. Further aspects of the invention relate to a cell comprising a nucleotide sequence coding for an APRIL-binding peptide according to the invention, a process for producing an APRIL-binding peptide and the APRIL-binding peptide obtainable in the production process and/or the selection method. In view of the possible utility of the APRIL-binding peptides according to the invention, further aspects of the invention relate to diagnostic uses of an APRIL binding peptide of the invention. | 2021-10-21 |
20210325405 | IDENTIFICATION OF PLATELET ACTIVATING ANTIBODIES - Described is a method for identifying pathogenic platelet-activating antibodies in a subject's blood and particularly antibodies implicated in heparin-induced thrombocytopenia (HIT) which comprises the preparation of a platelet releasate from a normal subject's platelets, the combination of the platelet release with a normal subject's platelets, a test subject's blood sample, and analyzing the sample for platelet activation. | 2021-10-21 |
20210325406 | PROTEIN NANOPORE FOR IDENTIFYING AN ANALYTE - Use of a metal embedded protein nanopore in identifying an analyte and use of MspA in identifying a metal-containing analyte are provided. Methods and Systems of identifying an analyte using a protein nanopore are also provided. Furthermore, a kit for identifying an analyte is provided, which contains a metal-containing compound and a protein that can form a nanopore. | 2021-10-21 |
20210325407 | SARS-COV-2 INFECTION BIOMARKERS AND USES THEREOF - Disclosed herein are methods that employ the use of one or more biomarkers for the treatment of SARS-CoV-2 infected individuals (COVID-19 patients). The methods may employ detection and measurement of one or more cytokines, the measurement of which may be used to treat COVID-19 patients with one or more immunomodulatory therapies. | 2021-10-21 |
20210325408 | METHOD FOR ASSISTING PREDICTION OF EXACERBATION OF RESPIRATORY INFECTION, AND DEVICE TO ASSIST IN PREDICTING EXACERBATION OF RESPIRATORY INFECTION - Disclosed is a method for assisting prediction of exacerbation of respiratory infection, comprising measuring a biomarker in a specimen collected from a subject suffering from a respiratory infection or a subject suspected of having a respiratory infection, wherein the biomarker is at least one selected from the group consisting of IFNλ3, CCL17, CXCL11, IP-10, IL-6 and CXCL9, and a measured value of the biomarker is used as an index to predict exacerbation of the respiratory infection. | 2021-10-21 |
20210325409 | BIOMARKERS AND USES THEREOF FOR DIAGNOSING THE SILENT PHASE OF ALZHEIMER'S DISEASE - The present invention relates to a molecular signature of the silent phase of Alzheimer's disease; and to methods using the same, for diagnosing a silent stage of Alzheimer's disease in a subject, stratifying a silent phase of Alzheimer's disease in a subject into different grades of the silent phase, prognosticating the progress of a silent phase of Alzheimer's disease in a subject, and determining a personalized course of treatment in a subject affected with a silent phase of Alzheimer's disease, it also relates to a computer system comprising a machine learning algorithm trained for diagnosing a silent phase of Alzheimer's disease in a subject. | 2021-10-21 |
20210325410 | APPARATUS AND METHOD FOR MEASURING GLYCATED HEMOGLOBIN - Provided is a glycated hemoglobin measuring apparatus. The apparatus for measuring glycated hemoglobin includes a cartridge for receiving blood and a plurality of chemicals, a rotating tray for rotating the cartridge, wherein the cartridge is disposed inside the rotating tray, a driver having a nozzle disposed above the cartridge and movable in a vertical direction, and a measurement unit located above the cartridge and measuring glycated hemoglobin of the blood, wherein the driver sucks at least one of the blood, the plurality of chemicals, and mixed solution of the blood and the plurality of chemicals into the nozzle or discharges the sucked at least one into the cartridge such that the blood is chemically treated through the plurality of chemicals. | 2021-10-21 |
20210325411 | Method For The Determination Of The Fingerprint In Varieties Of Cannabis - Method of obtaining a fingerprint from | 2021-10-21 |
20210325412 | AUTOMATED SAMPLE DEPOSITION AND STAINING SYSTEMS AND ASSOCIATED METHODS - Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element. | 2021-10-21 |
20210325413 | SAMPLE TESTING SYSTEM WITH AUTOMATED CONTROL OF SAMPLE RETESTING - A sample testing system comprising: a transporting apparatus; a testing apparatus for obtain a sample and performing testing on the obtained sample; and a controller. The controller executes operation of: controlling the transporting apparatus so as to transport the sample rack in first direction, such that each sample container held in a sample rack is transported to a obtaining position on which the testing apparatus obtains a sample and then the sample rack is transported toward the second position; changing, when retesting of a sample contained in a sample container is necessary, the transporting direction from the first direction to second direction, and then controlling the transporting apparatus so as to transport the sample container accommodating the sample, for which retesting is necessary, to the obtaining position again. Sample testing method and a computer program product are also disclosed. | 2021-10-21 |
20210325414 | REAGENT REPLACEMENT METHOD AND DEVICE OF AN ANALYZER - Disclosed are a reagent replacement method and device. The reagent replacement method includes: monitoring a working state of a sample analyzer in real-time, and reading failure information when it is detected that automatic sample conveying is suspended; identifying whether a reagent failure exists; if so, displaying a reagent setup window automatically to display information of at least one failed reagent; obtaining reagent information of a replacement reagent, and inputting at least part of the information into a corresponding place in the reagent setup window so as to set up the reagent; judging whether the setup of all the failed reagents is completed; if so, closing the reagent setup window; and executing a reagent reset on the replacement reagent after the setup or executing the reagent reset after the reagent setup window is closed. By means of the reagent replacement method, the operation process of reagent replacement is simplified. | 2021-10-21 |
20210325415 | Infectious Microbe Detection Method and Apparatus - The invention is a novel and economical method for detecting infectious microbes, whether airborne or bound to surfaces. A microbe is any microorganism, especially a virus, or bacteria, or fungal spore of any kind. Every infectious microbe has a specific path or vector to invade the human body and cause disease. This inspection and detection method utilizes a real or simulated human cell enzyme coating to bind the target microbe to the sample gathering filter or swab. This greatly increases the sample gathering sensitivity to the target microbe. | 2021-10-21 |
20210325416 | VIAL GRABBER INSPECTION APPARATUS - The present invention generally involves an apparatus and method for grabbing a plurality of vials from a container. In particular embodiments, the present invention may provide a reliable apparatus that a vial inspector may use to pick up a plurality of vials from a container of vials so that the vials can be inspected wherein the apparatus tends to standardize inspection output across a variety of users making the task more productive and production goals easier to establish. | 2021-10-21 |
20210325417 | Measuring arrangement - A measuring arrangement having a first dual conductor field device with a first sensor and a first dual conductor interface for the power supply of the first dual conductor field device and for the transmission of data from the dual conductor field device to a superordinate unit, wherein the first dual conductor field device has at least one second dual conductor interface suitably designed to receive data from at least one second dual conductor field device. | 2021-10-21 |
20210325418 | Detecting Device for Detecting Rotation Speed of Color Wheel, Light Source System and Projection Device - A detecting device for detecting a rotation speed of the color wheel includes: a first processing unit, used to compare an external ambient temperature with a preset temperature, and outputs a logic level when the external ambient temperature is greater than the preset temperature; and a light-emitting unit, including a light-emitting body for emitting measurement light, a temperature compensation circuit, wherein the temperature compensation circuit adjusts, according to the logic level and the external ambient temperature, the resistance of a circuit in which the light-emitting body is located, causing a driving current of the light-emitting body to be within a preset current range, a reflection unit disposed on a moving color wheel and used to reflect measurement light, and a measurement and control unit used to receive the measurement light emitted periodically by the reflection unit, and to calculate the number of times that the measurement light enters. | 2021-10-21 |
20210325419 | HYBRID FEEDBACK DEVICE - A feedback device is coupled to rotate with a rotating component of an aircraft engine. The feedback device comprises a body having cavities defined therein and circumferentially spaced thereabout, each cavity configured to receive therein a position marker, the body made of a non-ferromagnetic material and the position markers comprising a ferromagnetic material. A sealing member is configured to be secured to the body for retaining the position markers within the cavities. At least one sensor is positioned adjacent the feedback device and configured for producing, as the feedback device rotates about a longitudinal axis with the rotating component, at least one sensor signal in response to detecting passage of the position markers. A processing unit is communicatively coupled to the at least one sensor and configured to determine a rotational speed of the rotating component from the at least one sensor signal received from the at least one sensor. | 2021-10-21 |
20210325420 | RESOLVER INTERFACE SYSTEMS AND METHODS - A resolver interface system for a motor drive system includes a phase detector configured to be operatively connected to a rotation signal output of a resolver to receive a rotation signal therefrom and generate a phase difference signal. A differentiator is operatively connected to an output of the phase detector to convert the phase difference signal of the phase detector into a pulse output configured to be read by a processing system. | 2021-10-21 |
20210325421 | NON-NULLING GAS VELOCITY MEASUREMENT APPARATUS AND PERFORMING NON-NULLING MEASUREMENT OF GAS VELOCITY PARAMETERS - A non-nulling gas velocity measurement apparatus performs a non-nulling measurement of gas velocity parameters and includes: a non-nulling pitot probe; gas valves in fluid communication with a different entrant aperture of the non-nulling pitot probe via a different pressure channel; receives stagnant gas from the respective entrant aperture; receives a reference gas; receives a valve control signal; and produces a valve-selected gas based on the valve control signal, the valve-selected gas consisting essentially of the reference gas or the stagnant gas; and a plurality of differential pressure transducers, such that each differential pressure transducer: is separately and independently in fluid communication with a different gas valve, and that gas valve communicates the valve-selected gas to the differential pressure transducer; receives the valve-selected gas from the gas valve; and produces a differential pressure signal from comparison of the pressure of the valve-selected gas to a reference gas pressure. | 2021-10-21 |
20210325422 | SENSOR SYSTEM, INCLUDING A PLURALITY OF INDIVIDUAL AND SEPARATE SENSOR ELEMENTS - A sensor system including a plurality of individual and separate sensor elements. Each of the individual sensor elements is independently functional. The individual sensor elements of the sensor system being formed in one piece from parts of a wafer or a vertically integrated wafer stack. The sensor system including at least one separation structure, in particular a scribe line, between the individual and separate sensor elements. | 2021-10-21 |
20210325423 | ACCELERATION MEASURING DEVICE AND ACCELERATION MEASURING METHOD OF THE SAME - An acceleration measuring device includes a housing with an inner cavity, a reference substance disposed in the inner cavity, an elastic supporting member connected between the bottom portion of the inner cavity and the reference substance, a light source secured to a side of the reference substance, a lens secured to the reference substance that is positioned at a side of the light source away from the reference substance, an image sensor at a top portion of the inner cavity and located at a side of the lens away from the reference substance for receiving light emitted by the light source and scattered by the lens, and a processor configured to calculate displacement information of the reference substance in a vertical direction according to light received by the image sensor, and calculate an acceleration of the reference substance according to the displacement information. | 2021-10-21 |
20210325424 | Physical Quantity Sensor Module, Clinometer, And Structure Monitoring Device - A physical quantity sensor module includes: a resonant frequency shift based physical quantity sensor whose frequency adjusts with a adjust in physical quantity; a reference signal oscillator which outputs a reference signal; a frequency delta-sigma modulator which performs frequency delta-sigma modulation of the reference signal, using an operation signal based on a measurement target signal as an output from the resonant frequency shift based physical quantity sensor, and generates a frequency delta-sigma modulated signal; a first low-pass filter provided on an output side of the frequency delta-sigma modulator and operating synchronously with the measurement target signal as the output from the resonant frequency shift based physical quantity sensor; and a second low-pass filter provided on an output side of the first low-pass filter and operating synchronously with the reference signal. | 2021-10-21 |
20210325425 | Inertial Sensor, Electronic Apparatus, and Vehicle - The inertial sensor includes a substrate, stationary electrodes provided to the substrate, an element section including a movable body which is displaceable with respect to the stationary electrodes, and which has electrodes in a first portion and a second portion opposed to the stationary electrodes, a protrusion which limits a displacement of the movable body, and which has a detection electrode in a portion opposed to the first portion of the movable body, a drive circuit for outputting a drive signal to the element section, a contact detection circuit for outputting a detection signal due to a contact between the electrode in the first portion of the movable body and the detection electrode of the protrusion, a self-diagnostic circuit for outputting a test signal to the element section when receiving the detection signal from the contact detection circuit, and a determination circuit for determining whether or not a level of a signal output by the element section in response to the test signal is out of a threshold value. | 2021-10-21 |
20210325426 | BALL BEHAVIOR ANALYSIS APPARATUS - Provided is an analysis apparatus for analyzing a behavior of a ball that has a center of gravity and in which an acceleration sensor is installed at a position shifted from the center of gravity by a predetermined shift amount, the analysis apparatus including a control unit configured to derive a centrifugal acceleration that is applied to the acceleration sensor, based on acceleration data that is output by the acceleration sensor, and derive at least one of a direction of a rotation axis and a rotation speed of a spin of the ball, based on the predetermined shift amount and the centrifugal acceleration. | 2021-10-21 |
20210325427 | MULTIPLE METER DETECTION AND PROCESSING USING MOTION DATA - Apparatuses are disclosed for identifying portable devices carried by the same person. An example apparatus includes at least one memory, instructions on the apparatus, and a processor to execute the instructions to access media exposure data from at least one of a plurality of portable computing devices, access motion strings from each of the plurality of portable computing devices, each of said strings comprising a successive binary representation of motion over a first period of time, compare the motion strings in a processor to determine if at least two motion strings match within a predetermined threshold, and identify the devices that produced matching motion strings. | 2021-10-21 |
20210325428 | PAN-SHARPENING FOR MICROSCOPY - Techniques for generating full-spatial resolution, full spectral resolution image(s) from a 3D spectral-data cube for any spectral value within a given spectral range are provided without requiring the acquisition of all full-spatial resolution, full spectral resolution data by an instrument. The 3D spectral-data cube is generated from a limited number of full-spatial resolution, sparse spectral resolution data and a sparse-spatial resolution, full-spectral resolution data of the same area of the sample. The use of the 3D spectral-data cube reduces the data acquisition time. | 2021-10-21 |
20210325429 | INITIATING AND MONITORING THE EVOLUTION OF SINGLE ELECTRONS WITHIN ATOM-DEFINED STRUCTURES - A method for the patterning and control of single electrons on a surface is provided that includes implementing scanning tunneling microscopy hydrogen lithography with a scanning probe microscope to form charge structures with one or more confined charges; performing a series of field-free atomic force microscopy measurements on the charge structures with different tip heights, where interaction between the tip and the confined charge are elucidated; and adjusting tip heights to controllably position charges within the structures to write a given charge state. The present disclose also provides a Gibb's distribution machine formed with the method for the patterning and control of single electrons on a surface. A multi bit true random number generator and neural network learning hardware formed with the above described method are also provided. | 2021-10-21 |
20210325430 | SPLIT THIN-FILM PROBE CARD AND ELASTIC MODULE THEREOF - A split thin-film probe card and an elastic module thereof are provided. The elastic module includes an elastic cushion and a thin-film sheet. The elastic cushion has a plurality of partition slots so as to define a plurality of independent elastic segments. The thin-film sheet includes a carrier, a plurality of signal circuits disposed on the carrier, and a plurality of conductive protrusions that are respectively formed on the signal circuits. The carrier has a plurality of grooves so as to divide the carrier into a plurality of action segments respectively disposed on the independent elastic segments. The signal circuits are respectively disposed on the action segments. When any one of the conductive protrusions is pressed, only the corresponding independent elastic segment is deformed through the corresponding signal circuit and the corresponding action segment. | 2021-10-21 |
20210325431 | SIGNAL ANALYSIS METHOD AND MEASUREMENT SYSTEM - A signal analysis method is described. The signal analysis method comprises the following steps. An output signal is received from a device under test. A sampling point density is received and/or the sampling point density is determined based on the output signal. A response function of the device under test is determined based on the output signal and based on the sampling point density. The sampling point density represents a number of sampling points per frequency interval for determining the response function. The response function characterizes at least one property of the device under test as a function of frequency. Moreover a measurement system for determining a response function of a device under test is described. | 2021-10-21 |
20210325432 | HARDWARE TRIGGER GENERATION FROM A DECLARATIVE PROTOCOL DESCRIPTION - An oscilloscope includes an input port to receive an input signal, a trigger system coupled to the input port and operable to generate a trigger signal in response to detecting a trigger event in the input signal, the trigger system includes at least one finite state machine, and a snippet compiler configured to accept one or more Declarative Trigger Language (DTL) code snippets as an input, compile the one or more DTL code snippets into one or more state machine op codes, and output the one or more state machine op codes. The trigger system uses the one or more state machine op codes to configure the at least one finite state machine. | 2021-10-21 |
20210325433 | CURRENT DETECTION SYSTEM, CURRENT DETECTION METHOD, AND DETECTION APPARATUS - A current detection system, a current detection method, and a detection apparatus are provided. The current detection system includes a printed circuit board and N groups of amplification apparatuses, wherein N is a positive integer greater than or equal to 1. Each group includes at least one amplification apparatus. N Rogowski coils are mounted on the printed circuit board. The n | 2021-10-21 |
20210325434 | Current Sensor Having A Flux Concentrator For Redirecting A Magnetic Field Through Two Magnetic Field Sensing Elements - A method can use a current sensor that can include a magnetic flux concentrator along with first and second magnetic field sensing elements disposed proximate to the magnetic flux concentrator, wherein the magnetic flux concentrator is operable to influence a direction of first and second magnetic fields at the first and second magnetic field sensing elements, respectively, the first and second magnetic fields resulting from an electrical current passing through a conductor, the first and second magnetic field sensing elements operable to generate first and second signals, respectively, in response to the first and second magnetic fields, respectively, wherein the current sensor can also include a differencing circuit operable to subtract the first and second signals to generate a difference signal related to the electrical current. | 2021-10-21 |
20210325435 | SEMICONDUCTOR SAMPLE INSPECTION DEVICE AND INSPECTION METHOD - An inspection device includes a reference signal output section, a noise removal section, and an electrical characteristic measurement section. The reference signal output section is connected to an external power supply device in electrical parallel with a semiconductor sample, and outputs a reference signal according to the output of the external power supply device. The noise removal section outputs a noise removal signal obtained by removing a noise component of the output of the external power supply device from the current signal output from the semiconductor sample based on the reference signal. The electrical characteristic measurement section measures the electrical characteristic of the semiconductor sample based on the noise removal signal. The inspection device measures the electrical characteristic of the semiconductor sample to which a voltage is being applied by the external power supply device and which is being irradiated and scanned with light. The inspection device outputs a defective portion of the semiconductor sample based on the electrical characteristic. | 2021-10-21 |
20210325436 | PULSE MEASUREMENT DEVICE - A pulse measurement device is provided, including a first signal source, a second signal source, two microwave resonators, two mixers, and a signal processing unit. The first signal source and the second signal source output a first high-frequency signal and a second high-frequency signal, respectively. Each of the microwave resonators generates an electric field according to the first high-frequency signal, and senses a variation in the electric field which is interfered by a pulse to obtain a sensing signal. Each of the mixers is coupled to one of the microwave resonators, to mix the sensing signal and the second high-frequency signal to output a down-converted signal. The signal processing unit respectively demodulates amplitudes of the down-converted signals of the two mixers to obtain amplitude signals. | 2021-10-21 |
20210325437 | Cached Peak Graphical Display for Spectrum Analyzers - A spectrum analyzing device and method include sweeping a first frequency range at least once at a first resolution and performing a Fast Fourier Transform (FFT) on data from the sweeping of the first frequency range to produce first peak hold trace data. A second frequency range is swept at least once at a second resolution and an FFT applied to produce second peak hold trace data based on the sweeping of the second frequency range. The resolution for the sweeps is selected based on a bandwidth of the frequency range to be swept. A composite graphical display is produced based upon the first and second peak hold trace data. By caching the peak hold trace data, the spectrum analyzer preserves detected signal information when zooming from a coarser to a finer frequency resolution while minimizing the processing requirements of the spectrum analysis. | 2021-10-21 |
20210325438 | RADIATED EMISSION MEASUREMENT METHOD AND RADIATED EMISSION MEASUREMENT SYSTEM - A radiated emission measurement method includes a prescan measurement step of performing broadband measurement including detection of a peak and detection of a quasi-peak by one fast Fourier transform in a target measurement frequency range; a calculation step of calculating a difference in level between the peak and the quasi-peak obtained for a measurement frequency to be a candidate for a result of measurement; a determination step of determining whether the obtained difference is less than a reference value; and an output step of outputting a result obtained as an interference level of the radiated emission in the broadband measurement when it is determined that the difference is less than reference value, and performing narrowband measurement and outputting the obtained result as the interference level of the radiated emission, when it is determined that the difference is equal to or higher than the reference value. | 2021-10-21 |
20210325439 | SOFTWARE SIMULATION SYSTEM FOR INDOOR EMC TEST - According to some embodiments, a method of performing EMC testing of an ADV can be used According to some embodiments, a method of performing EMC testing of an ADV can be used to test how software and hardware components in the ADV are impacted in an indoor EMC testing environment. According to the method, the ADV can be positioned at a fixed spot in the indoor EMC testing environment, and can be driven in an autonomous driving mode for a predetermined period of time. One or more of the autonomous driving modules of the ADV are modified to accommodate the positioning of the ADV at the fixed spot and the indoor EMC testing environment. The ADV can determine if each of a plurality of performance parameters meets its performance metric during the predetermined period of time. If each performance parameters meets its performance metric, the ADV is considered to have passed the EMC testing. | 2021-10-21 |
20210325440 | METHODS FOR DETECTING SENSOR FAULTS IN A CONSUMER APPLIANCE - A method for operating a consumer appliance, as provided herein, may include detecting a preliminary first conversion value from a first sensor input pin electrically connected to an analog-to-digital converter (ADC) and detecting a preliminary second conversion value from a second sensor input pin electrically connected to the ADC in electrical parallel with the first sensor input pin. The method may further include determining a preliminary variation between the preliminary first and second conversion values is less than or equal to a predetermined preliminary threshold. The method may still further include activating a pull-up resistor in electrical communication with the first sensor input pin, identifying a fault state in response based on a conversion value variation following activating the pull-up resistor, and directing the appliance based on the determined fault state. | 2021-10-21 |
20210325441 | DETECTION OF ANOMALIES IN AN ELECTRICAL NETWORK - The disclosed method detects anomalies in an electrical network. An ohmic matrix model of the network is initially generated from consumption measurements produced by meters connected to a same transformer. The model has currents carried by the meters as input, relative voltage drops of the meters referenced to a voltage of a reference node located on the network as output, and resistive quantities initially determined by currents and voltages based on the consumption measurements as matrix terms, the relative voltage being a voltage difference between a voltage determined for a meter and an average of voltages determined for a set of meters of the network. The model is iteratively modified according to detected anomalies, and a diagnosis of the network characterizing the detected anomalies is provided. | 2021-10-21 |
20210325442 | OVERHEAD POWER LINE INSULATOR INCLUDING A LEAKAGE CURRENT MEASUREMENT DEVICE HAVING EXTENDED BATTERY LIFE - An overhead power line insulator is provided including a device for detecting and measuring a leakage current and for transmitting data, the device being arranged in such a manner as to perform: measuring a leakage current of an insulator during a first measurement period and during a second measurement period in a measurement circuit; comparing two values of the current that are obtained during respective ones of the two measurement periods; and stopping the measurement circuit for a certain sleep period of time if the second value of the current is less than or equal to the first value of the current, and then starting the measurement circuit again after the certain sleep period of time. | 2021-10-21 |
20210325443 | DETERMINATION OF POWER MOSFET LEAKAGE CURRENTS - An example method provides a power MOSFET, a voltage source coupled to the power MOSFET, and a current measurement device coupled to a first non-control terminal of the power MOSFET. The voltage source, the current measurement device, and a second non-control terminal of the power MOSFET couple to ground. The method uses the voltage source to apply a voltage between a gate terminal and the second non-control terminal of the power MOSFET, the voltage greater than zero volts and less than a threshold voltage of the power MOSFET. The method also uses the current measurement device to measure a first current flowing through the first non-control terminal while applying the voltage. The method further uses the first current to predict a second current through the first non-control terminal for a voltage between the gate terminal and the second non-control terminal that is approximately zero. | 2021-10-21 |
20210325444 | METHOD AND SYSTEM FOR CONTROLLING AN ELECTRONIC DEVICE HAVING SMART IDENTIFICATION FUNCTION - Disclosed are an facilitating debugging electronic device, system and method, reasonably integrates the power-supply interface and the signal interface of the electronic device, matches the conventional output end of the electronic device with the master device, realizes the debugging of electronic devices including semi-finished products of PACKAGE (SMD)/PCBA/COB modules and electronic products, partly overcomes the technical problem of the increase of product volume and cost, which caused by setting different interfaces on electronic devices for various testing, burning and correcting purposes. The present disclosure also partly realizes the debugging of electronic devices with fewer external interfaces, which contributes to the miniaturization of electronic devices such as semi-finished products of PACKAGE (SMD)/PCBA/COB modules and electronic products, and guarantees the quality of electronic products by implementing the waterproof, dustproof and pleasing design of the housing structure of devices and achieves economic and social benefits. | 2021-10-21 |
20210325445 | PREDICTIVE CHIP-MAINTENANCE - The disclosure describes to techniques for detecting field failures or performance degradation of circuits, including integrated circuits (IC), by including additional contacts, i.e. terminals, along with the functional contacts that used for connecting the circuit to a system in which the circuit is a part. These additional contacts may be used to measure dynamic changing electrical characteristics over time e.g. voltage, current, temperature and impedance. These electrical characteristics may be representative of a certain failure mode and may be an indicator for circuit state-of-health (SOH), while the circuit is performing in the field. | 2021-10-21 |
20210325446 | METHOD FOR TESTING A POWER MODULE - A method for testing a power module includes connecting an output capacitor of the power module to a load meter; inputting an input signal, an enable signal, a PowerGood signal, and an output signal of the power module to first, second, third, and fourth channels of an oscillometer, respectively; adjusting the load meter to a no-load state, and capturing and storing the power-on waveforms and power-off waveforms of four channels of signals of the power module; adjusting the load meter to a full-load state, and capturing and storing the power-on waveforms and power-off waveforms of the four channels of signals of the power module; and determining whether the power-on sequence, power-off sequence, overshoot voltage value, and undershoot voltage value of the power module are normal based on the power-on waveforms and power-off waveforms of the four channels of signals stored by the load meter under the no-load and full-load states. | 2021-10-21 |
20210325447 | Electrical Power Analyzer for Large and Small Scale Devices for Environmental and Ecological Optimization - A device, system, and a computer-implemented method a for identifying an anomaly in an operation of a device includes comparing, by an electrical power analyzer, a current power draw signature of the device with a known power draw signature of the device. There is a determining as to whether at least one anomaly is present in the current power draw signature. A warning is generated in response to determining the at least one anomaly is present in the current power draw signature. | 2021-10-21 |
20210325448 | TESTING DEVICE OF ARRAY SUBSTRATES AND TESTING METHOD - The present application discloses a testing device of array substrates and a testing method. The testing device of array substrates includes: a machine and testing interfaces, the testing interfaces being disposed on the machine; and testers disposed above the machine. There are at least two sets of testers, and the testers synchronously operate according to a preset scheme. | 2021-10-21 |
20210325449 | METHOD OF PREPARING COMPOSITE MATERIAL FOR SEMICONDUCTOR TEST SOCKET THAT IS HIGHLY HEAT-DISSIPATIVE AND DURABLE, AND COMPOSITE MATERIAL PREPARED THEREBY - This application relates to a method of preparing a composite material for a semiconductor test socket, and a composite material prepared through the method. In one embodiment, the method includes preparing a powder mixture including (i) a metal powder comprising aluminum or aluminum alloy particles and magnesium particles and (ii) a polymer powder. The method may also include sintering the powder mixture to produce the composite material using a spark plasma sintering (SPS) process. This application also relates to a method of manufacturing a semiconductor test socket, the method including forming an insulating portion of the semiconductor test socket with the composite material. This application further relates to a semiconductor test socket produced through the method. | 2021-10-21 |
20210325450 | TEST APPARATUS FOR TESTING SEMICONDUCTOR PACKAGES AND AUTOMATIC TEST EQUIPMENT HAVING THE SAME - A test apparatus and an automatic test equipment having the same are disclosed. The test apparatus includes a test head having a test area, a socket board combined to the test area of the test, the socket board including a socket body and an active device attached on a first surface of the socket body, the active device configured to operate a semiconductor package, and a heat exchanger arranged on an upper portion of the test head, the heat exchanger being in contact with the socket board. | 2021-10-21 |
20210325451 | WAFER PROBER TO FACILITATE TESTING OF A WAFER USING NANOSECOND PULSES - A wafer testing system may comprise a chuck, a wafer carrier, a cathode plate, and a probe card. The chuck may be configured to hold the wafer carrier. The wafer carrier may be configured to hold a wafer on a surface of the wafer carrier, wherein the surface of the wafer carrier comprises one or more contact features protruding from the surface of the wafer carrier. The cathode plate may be configured to provide an electrical connection between the wafer carrier and the probe card, wherein a portion of a surface of the cathode plate is configured to be disposed on the one or more contact features of the wafer carrier. The probe card may be configured to test, using one or more probes associated with the probe card, the wafer when the wafer is on the surface of the wafer carrier. | 2021-10-21 |
20210325452 | THERMAL TEST HEAD FOR AN INTEGRATED CIRCUIT DEVICE - A thermal test head for an integrated circuit device includes a heat exchanger assembly, a contact assembly configured to contact the integrated circuit, and a thermal control assembly disposed between the heat exchanger assembly and the contact assembly. The thermal control assembly includes a Peltier device in thermal contact with opposing surfaces of the heat exchanger assembly and the contact assembly, and a spacer in physical contact with the opposing surfaces of the heat exchanger assembly and the contact assembly. | 2021-10-21 |
20210325453 | THERMAL TEST HEAD FOR AN INTEGRATED CIRCUIT DEVICE - A thermal test head for an integrated circuit device includes a heat exchanger assembly, a contact assembly configured to contact the integrated circuit, and a thermal control assembly disposed between the heat exchanger assembly and the contact assembly. The thermal control assembly includes a Peltier device in thermal contact with opposing surfaces of the heat exchanger assembly and the contact assembly, and a spacer in physical contact with the opposing surfaces of the heat exchanger assembly and the contact assembly. | 2021-10-21 |
20210325454 | SEMICONDUCTOR PACKAGE WITH PREDICTIVE SAFETY GUARD - The disclosure describes techniques for detecting failures or performance degradation of a device including an integrated circuit (IC) components in the field by including additional contacts, i.e. terminals, along with functional contacts of the circuit used for connecting the circuit to a system in which the circuit is a part. These additional contacts may be internal external to the package surface and may be used to measure dynamic changing electrical characteristics over time e.g. voltage, current, capacity, temperature and impedance. These electrical characteristics may be representative of one or more failure modes and may be treated as indicator for device state-of-health (SOH). | 2021-10-21 |
20210325455 | DIE-TO-DIE CONNECTIVITY MONITORING - An input/output (I/O) sensor for a multi-IC module. The I/O sensor includes: delay circuitry, configured to receive a data signal from an interconnected part of an IC of the multi-IC module and to generate a delayed data signal, the delay circuitry including an adjustable delay-line configured to delay an input signal by a set time duration; a comparison circuit, configured to generate a comparison signal by comparing the data signal with the delayed data signal; and processing logic, configured to set the time duration of the adjustable delay-line and, based on the comparison signal, identify a margin measurement of the data signal for determining an interconnect quality parameter. | 2021-10-21 |
20210325456 | REDUCED SIGNALING INTERFACE METHOD & APPARATUS - This disclosure describes a reduced pin bus that can be used on integrated circuits or embedded cores within integrated circuits. The bus may be used for serial access to circuits where the availability of pins on ICs or terminals on cores is limited. The bus may be used for a variety of serial communication operations such as, but not limited to, serial communication related test, emulation, debug, and/or trace operations of an IC or core design. Other aspects of the disclosure include the use of reduced pin buses for emulation, debug, and trace operations and for functional operations. | 2021-10-21 |
20210325457 | SCAN OUTPUT FLIP-FLOP WITH POWER SAVING FEATURE - A scan output flip-flop includes a selection circuit, a control circuit, and a scan-out stage circuit. The selection circuit is controlled by a first test enable signal to transmit a data signal on a first input terminal or a test signal on a second input terminal to an output terminal to serve as an input signal. The control circuit is controlled by a first clock signal and a second clock signal to generate a first control signal and a second control signal according to the input signal. The scan-out stage circuit receives only one of the first control signal and the second control signal, and is controlled by the first test enable signal and a second test enable signal to generate a scan-out signal. | 2021-10-21 |
20210325458 | ASYNCHRONOUS CIRCUITS AND TEST METHODS - Circuits, methods, and systems are provided which facilitate testing of asynchronous circuits having one or more global or local feedback loops. A circuit includes a data path and a scan path. The data path has an input configured to receive a data input signal, and a first output. The scan path includes a first multiplexer having a first input configured to receive the data input signal, a latch coupled to an output of the first multiplexer, a scan isolator coupled to an output of the latch, and a second multiplexer having a first input coupled to the first output of the data path and a second input coupled to an output of the scan isolator. The second multiplexer is configured to output a data output signal. | 2021-10-21 |