47th week of 2011 patent applcation highlights part 35 |
Patent application number | Title | Published |
20110286833 | VACUUM PUMP - A vacuum pump has the outer side of the pump housing provided with retaining elements. These serve to receive at least one mass element. With these mass elements, which are preferably arranged asymmetrically with respect to the longitudinal axis of the vacuum pump, vibrations that occur can be suppressed. | 2011-11-24 |
20110286834 | GUIDE VANE FOR A GAS TURBINE - A guide vane is provided for a gas turbine and has an airfoil extending in the radial direction between an inner platform and an outer platform. The airfoil extends transversely to the direction of the hot gas flow between a leading edge and a trailing edge and has a pressure side and a suction side. A cooling slot running parallel to the trailing edge is provided on the pressure side in front of the trailing edge, a cooling medium can exit through the cooling slot from the guide vane over the entire length of the guide vane and can cool the trailing edge of the guide vane. In such a guide vane, the service life is extended by a thermal stress reducing element provided on the inner platform below the trailing edge and the cooling slot. | 2011-11-24 |
20110286835 | TURBOMACHINE HAVING A COMPENSATING PISTON - A turbomachine including a compensating piston that is sealed by means of a seal with respect to a stator is provided. Conventional compensating pistons consume significant amounts of process fluid, which can cause a considerable loss of efficiency. The turbomachine provides the solution in that the stator partially carrying the seal is designed to be axially moveable in the housing such that the permeability of the seal can be changed in this way. | 2011-11-24 |
20110286836 | GEARED TURBOFAN ENGINE WITH INTEGRAL GEAR AND BEARING SUPPORTS - A gas turbine engine includes a bearing and a bearing support having a second wall extending between first and second ends and operatively supported by the bearing at a first end. An engine case is secured to the second end radially outward of the first end. A second wall integral with and extending transversely from the first wall provides a flexible support. The second wall has a flange, and a gear train component is secured to the flange. A gas turbine engine includes a support structure which supports the main rotatable structure via bearings and gear train components. The support provides both the necessary structural support for the rotor structure as well as desired flexibility for a fan drive gear system. | 2011-11-24 |
20110286837 | EXHAUST-GAS TURBOCHARGER - An exhaust-gas turbocharger includes an outer housing, a bearing flange connected to the outer housing by a material joint, and a turbine wheel rotatable about a rotation axis. Formfittingly connected to the bearing flange is an inner housing which is formed with a collar having at least one section in contact with an inner edge of the bearing flange in a direction of the rotation axis of the turbine wheel. | 2011-11-24 |
20110286838 | TURBOCHARGER HAVING FASTENING ELEMENTS FOR FASTENING VANE BEARING RINGS OF A VARIABLE TURBINE GEOMETRY VTG - A turbocharger with a variable turbine geometry device has one or two blade bearing rings. At least one or more fastening elements are provided for fastening the one or two blade bearing rings. The respective fastening element has at least one section formed with a knurl and/or at least one section formed with at least one or several notches. | 2011-11-24 |
20110286839 | FAN CASE WITH RUB ELEMENTS - A turbofan engine comprising an annular inner wall surrounding tips of the fan blades, a layer of insulating material surrounding the inner wall, and an outer casing including an annular outer wall surrounding the insulating material and concentric to the inner wall and at least two annular rub elements extending radially inwardly from the outer wall through only part of a radial thickness of the layer of insulating material, at least two of the rub elements being in axial alignment with the blade tips at every point around a circumference of the fan, each rub element having a radially inner end spaced apart from the inner wall and made of a material harder than that of the blades, and a containment fabric layer wrapped around a support structure of the outer wall. | 2011-11-24 |
20110286840 | LIQUID RING PUMP WITH LINER - A liquid ring pump is provided that includes an annular housing having an inner surface forming a housing cavity. The annular housing is filled with an operating fluid during operation of the pump. The operating fluid forms an eccentric liquid ring in the annular housing during operation of the pump. A rotor is disposed in the housing cavity and includes a plurality of rotor blades. A shaft extends into the annular housing into the housing cavity. The plurality of rotor blades extend radially outward from the shaft toward the inner surface of the annular housing. A liner formed from a corrosion resistant material is disposed substantially flush with at least a portion of the annular housing inner surface opposite a plurality of rotor blade ends. | 2011-11-24 |
20110286841 | COUNTER-ROTATING OPEN-ROTOR (CROR) - A method of controlling a Counter-Rotating Open-Rotor (CROR) includes measuring a speed of a first rotor and deriving a speed of a second rotor and controlling a pitch of the first rotor and the second rotor. | 2011-11-24 |
20110286842 | COUNTER-ROTATING OPEN-ROTOR (CROR) - A method of controlling a Counter-Rotating Open-Rotor (CROR) includes mechanically linking a pitch change system of a first rotor with a pitch change system of a second rotor and commanding a Blade Angle (Beta1 commanded) of the first rotor such that a Blade Angle (Beta2 Actual) of the second rotor is a function of the commanded Blade Angle (Beta1 commanded) to provide a linear relationship between an actual Blade angle (Beta1 Actual) and Beta1 commanded of the first rotor and a non-linear relationship between Beta2 Actual and Beta1 commanded. | 2011-11-24 |
20110286843 | DRIVE DEVICE FOR DRIVING SEVERAL AXLES - A drive device for driving at least one first axle and one second axle (axle | 2011-11-24 |
20110286844 | LUBRICANT HEATING MECHANISM, GEAR MECHANISM , AND WIND TURBINE GENERATOR USING THE SAME - A lubricant heating mechanism is provided with a tank accumulating therein lubricant; a lubricant pump; a heater provided in the tank to heat the lubricant; and a baffle plate at least partially covering the heater. The tank is provided with a suction port drawing out the lubricant from the tank to the lubricant pump. The baffle plate is provided to convect the heated lubricant toward the suction port. | 2011-11-24 |
20110286845 | HYDRAULIC ACTUATOR LOCKING DEVICE - A hydraulic lock system includes a spring pack defined between a female spring support and a male spring support, the spring pack includes a multiple of serrated washers, each of which defines an inner diameter which is greater than a diameter of the actuator rod and an outer diameter greater than an inner diameter of the cylinder. | 2011-11-24 |
20110286846 | SUN-AND-PLANET SPEED-UP GEAR - A sun-and-planet speed-up gear includes a low-speed-stage sun-and-planet gearing and a high-speed-stage sun-and-planet gearing, in which an input shaft is connected to a low-speed-stage ring gear, the position of a shaft of a low-speed-stage planet gear is secured, a shaft of a low-speed-stage sun gear is connected to a high-speed-stage carrier, and an output shaft is connected to a high-speed-stage sun gear. In order to automatically center the low-speed-stage sun gear to prevent damage to gears and a bearing, a flange formed at a tip of the shaft of the low-speed-stage sun gear and a flange formed at a tip of a coupling that is directly attached to the high-speed-stage carrier or that is formed on the high-speed-stage carrier are coupled via a sleeve. | 2011-11-24 |
20110286847 | GAS TURBINE ENGINE VANES - One embodiment of the present invention is a gas turbine engine. Another embodiment is a gas turbine engine vane system. Other embodiments include apparatuses, systems, devices, hardware, methods, and combinations for gas turbine engine vanes. Further embodiments, forms, features, aspects, benefits, and advantages of the present application shall become apparent from the description and figures provided herewith. | 2011-11-24 |
20110286848 | INDUSTRIAL FAN IMPELLER HAVING A TAPERED BLADE AND METHOD - An industrial fan impeller that includes blades having an outer edge with a tapered portion and a level portion and method of manufacture are provided. The industrial fan impeller includes a front plate with a first diameter and a back plate with a second diameter larger than the first diameter of the front plate. Blades are attached to the front plate and the back plate. Individual blades have an outer edge with a tapered portion and a level portion. The blades are positioned between the front plate and the back plate such that the tapered portion of the outer edge of the individual blades tapers towards the front plate of the industrial fan impeller. | 2011-11-24 |
20110286849 | BLADE FOR A GAS TURBINE - A blade is disclosed for a gas turbine including an airfoil, which extends along a longitudinal axis from a blade root to a blade tip, and has a shroud segment at the blade tip. The shroud segment abuts with first and second edges against shroud segments of adjacent blades to form a ring-like shroud. The first and second edges are each provided with a respective side rail on the upper side of the shroud segment. Each of the side rails is subdivided into sections of different height and/or width. | 2011-11-24 |
20110286850 | AIRFOIL FOR A COMPRESSOR BLADE - The present disclosure provides an improved first stage airfoil for a compressor blade having a unique chord length (CD) stagger angle (γ) and camber angle (Δβ). The stagger angle (γ) and camber angle (Δβ) provide improved aerodynamics while the chord length (CD) provides for reduced airfoil weight. | 2011-11-24 |
20110286851 | Guide blade arrangement for an axial turbo-machine - A guide blade arrangement for an axial turbo-machine is provided. The guide blade arrangement includes at least one annular guide blade carrier and an inner ring arranged concentrically with respect to the guide blade carrier, between which guide blade carrier and inner ring a number of guide blades are arranged in a radial configuration. To obtain a low-wear and particularly durable fastening of the guide blade, which is supported by the guide blade carrier, to the inner ring, it is proposed that the guide blades are fastened resiliently to the inner ring. Here, the fastening is provided by means of a spring element. By means of the spring element, it is possible to ensure a uniform contact pressure of the guide blade head against the inner ring or if appropriate against a further spring element, such that occurring stresses and wear can be reduced. | 2011-11-24 |
20110286852 | WIND TURBINE BLADE - Disclosed is a blade including a blade body including a leading edge and a trailing edge, and at least one trailing edge cavity defined by a blade area disposed in at least partial alignment with the trailing edge, the at least one cavity extending a desired depth into said blade body in a direction of the leading edge. | 2011-11-24 |
20110286853 | BLADE OF A WIND TURBINE - A blade of a wind turbine is provided. The blade includes different layers, which are used to build up the three-dimensional shape of the blade. Resin is applied to connect the layers while the blade is manufactured. A reinforcement structure is arranged close to the surface of the blade and at a resin-rich-section of the blade, where a certain amount of resin is gathered during the manufacture of the blade. | 2011-11-24 |
20110286854 | AIRFOIL COMPONENT - An airfoil component includes an aluminum alloy body having at least an airfoil portion and a root portion. A metallic layer is located on at least a portion of the aluminum alloy body and an electrochemically insulating layer is located between and adjoining the aluminum alloy body and the metallic layer. | 2011-11-24 |
20110286855 | JACKET IMPELLER WITH FUNCTIONAL GRADED MATERIAL AND METHOD - Devices and methods provide for an impeller for use in a compressor. A method for manufacturing the impeller includes: attaching an intermediate layer to a base metal by placing a first metal powder into a gap between a first insert and the base metal; processing with hot isostatic pressing the base metal, the first metal powder and the first insert such that the intermediate layer is bonded to the base metal; attaching an external layer to the intermediate layer by placing a second powder into a gap between a second insert and the intermediate layer; processing the base metal, the intermediate layer, the second metal powder and the second insert via hot isostatic pressing such that the external layer is bonded to the intermediate layer; and removing the second insert to form the impeller, wherein the external layer is corrosion resistant. | 2011-11-24 |
20110286856 | AIRFOIL FOR A COMPRESSOR BLADE - The present disclosure provides an improved second stage airfoil for a compressor blade having a unique chord length (CD) stagger angle (γ) and camber angle (Δβ). The stagger angle (γ) and camber angle (Δβ) provide improved aerodynamics while the chord length (CD) provides for reduced airfoil weight. | 2011-11-24 |
20110286857 | CERAMIC CORE TAPERED TRIP STRIPS - A core for creating an airfoil has a ceramic material that forms a body. The body has an outer dimension, a slot extending through the outer dimension and into the body for receiving an insert, the slot disposed at an angle to the outer dimension, and a trip strip having a first portion disposed in the outer dimension. The first portion is in register with the slot wherein a constant dimension such as minimum thickness is maintained between the trip strip and the slot along a length of the slot and wherein said first portion tapers towards said outer dimension. | 2011-11-24 |
20110286858 | WATER PUMP SYSTEM AND METHOD - This disclosure relates a water pump control system for an internal combustion engine, and a method for operating an internal combustion engine including a clutch-controlled water pump. The water pump control system and method provide protection of the pump impeller during dry pump operation, such as when a watercraft engine is started while the watercraft is out of water, by turning off the clutch-controlled pump when no water is detected at the inlet of the water pump. | 2011-11-24 |
20110286859 | Pump Controller With External Device Control Capability - A variable speed motor controller senses the electrical load on the motor in turning a pump. An output of the controller may be used to trigger a vent valve or power to the motor may be cut if the load level indicates a restricted flow of fluid into the suction side of the pump, such as would be caused by drain occlusion in a swimming pool. A sensor in communication with the suction side of the pump ascertains a vacuum/pressure level present and may be used to verify that an intended operational state for the variable speed motor and the pump is actualized, otherwise anomaly processing is invoked. This pressure/vacuum monitoring may be conducted through speed changes of the motor/pump. | 2011-11-24 |
20110286860 | Method for Controlling a Compressor Installation - A method for controlling a compressor system comprising a plurality of compressors, wherein the compressor system is intended to maintain a predefined excess pressure in a pressurized fluid system, wherein decisions are met at fixed or variable intervals as to switching operations for adapting the system to current conditions, wherein—in a pre-selecting step, switching alternatives are excluded from the plurality of combinatorially available switching alternatives, —in a main selecting step, remaining switching alternatives are weighed against one another while referring to one or more optimization criterion (criteria) and optimum switching alternatives are selected from among the given criteria, and—in a control step, the selected switching alternative is output for implementation in the compressor system. | 2011-11-24 |
20110286861 | AIR COMPRESSOR SYSTEM AND METHOD OF OPERATION - Air compressor systems, upgrade kits, computer readable medium, and methods for controlling an air compressor for improved performance. The methods may include receiving a working air requirement; determining an estimated air pressure of the air compressor to deliver the working air requirement; measuring a pressure of the air compressor; comparing the measured pressure with the calculated estimated air pressure; if the measured pressure of the air compressor is greater than the determined estimated air pressure by a predetermined greater amount, then decreasing an output control of the air compressor; and if the measured pressure of the air compressor is less than the calculated estimated air pressure by a predetermined lesser amount then increasing the output control of the air compressor. The air compressor may be controlled based on a measured pressure of delivered working air. An oil control system may shut off oil to parts of the air compressor. | 2011-11-24 |
20110286862 | PUMP FOR A LUBRICATING SYSTEM OF A COMBUSTION ENGINE - A pump is provided for a lubricating system of a combustion engine that includes, but is not limited to a housing and a lid that together define a pump hollow space in which a pump mechanism for the pumping of lubricant of the lubricating system is arranged. The pump hollow space includes, but is not limited to at least one intake opening and at least one discharge opening. The pump additionally includes, but is not limited to a regulating valve for regulating a flow of the lubricant through the pump, which is integrated in the lid. | 2011-11-24 |
20110286863 | AUXILIARY SYSTEM FOR A DRIVE DEVICE - An auxiliary drive system for a water pump includes a pump housing that is mounted to an engine block. The pump housing includes an impeller shaft that passes therethrough. One end of the impeller shaft has an impeller mounted thereon, which is part of the water pump. A second end of the impeller shaft is supported by an internal bearing to allow for rotation of the impeller shaft. An external bearing is disposed around, but not in contact with the impeller shaft or the internal bearing. The external bearing is in communication with and is driven by an engine belt, such as a timing belt, which helps rotate the impeller shaft and the impeller in accordance with engine operation. A collapsible gear is disposed between and effectuates engagement of the external bearing and the impeller shaft such that if the amount of force required to be exerted by the belt exceeds a certain predetermined threshold, the collapsible gear fails and thereby prevents damage to the engine. | 2011-11-24 |
20110286864 | MULTIPLE INLET VACUUM PUMPS - First and second pump stages provide a flow-path from an inlet to the outlet ( | 2011-11-24 |
20110286865 | HERMETIC COMPRESSOR - A compressor has a rotation shaft in a hermetic container, and first and second bearings to support the shaft in the container. A tolerance between the second bearing and the rotation shaft and a tolerance between the first bearing and the rotation shaft are different, so as to cause hydrodynamic lubrication to occur at one of the first or second bearings. | 2011-11-24 |
20110286866 | AC Power Unit Operating System For Emergency Vehicles - An AC operating system has an electrical distribution panel; a variable frequency drive control unit having a first variable frequency drive and a second variable frequency drive; a hydraulic oil heat exchanger; and a hydraulic power unit. The hydraulic power unit includes a housing having a first electric motor connected to the first variable frequency drive and a second electric motor connected to the second variable frequency drive. A first pump and valve assembly is connected to the first electric motor and a second pump and valve assembly is connected to the second electric motor. A motor start command is transmitted from the electrical distribution panel to at least one of the variable frequency drives. The variable frequency drive controller ramps up power to the selected motor to begin rotation of the motor to a predetermined operating speed in a predetermined amount of time. | 2011-11-24 |
20110286867 | Mud Pump - A mud pump is provided that includes a pump shaft having substantially circular eccentric lobes. Each lobe is rotatably mounted in a connecting rod that, in turn, moves a slide in a horizontal and linearly manner. A piston rod is operatively couples a pump module to one or both sides of each slide frame and a pump module. As the pump shaft turns, each lobe causes the slide to move side to side. As the slide moves side to side, each piston rod operates a pump module whose outputs can be coupled to a common manifold. | 2011-11-24 |
20110286868 | ELECTROMAGNETIC PUMP WITH OSCILLATING PISTON - An electromagnetic pump is provided, which includes a hollow tubular body extending along a longitudinal direction, a piston mounted so as to be able to move inside the hollow tubular body, a solenoid, supplied with alternating current and assembled around at least a portion of the body and a magnetic envelope surrounding at least a portion of the body. The presence of a magnet magnetised longitudinally in a predetermined direction and a magnetic envelope orienting and channelling flux lines created by the magnet either around the solenoid or directly inside themselves creates an oscillating magnetic force on the piston. | 2011-11-24 |
20110286869 | SUPPORT STRUCTURE OF A COOLING FAN - A support structure of a cooling fan includes a base and a tube. The base has a raised section perpendicularly extending from the base and defining a first opening with a first inner diameter. A reception section is formed between the base and the raised section and has a first end and a second end connected with the raised section and base respectively. A second opening is formed between the first and second ends in communication with the first opening and has a second inner diameter equal to the first inner diameter and a third inner diameter larger than the second inner diameter. The tube is fitted in the first and second openings and has a first flange and a second flange mated with the raised section and reception section respectively. The second flange has a third end and a fourth end corresponding to the first and second ends respectively. | 2011-11-24 |
20110286870 | System and Method for Holding Tubing for a Peristaltic Pump that Prevents Tubing Stretch or Deformation - An enhancement for a peristaltic pump that, in a particular embodiment, can be a thin concave spring member or other mechanism with at least one tubing notch adapted to be mounted on a peristaltic pump frame such that peristaltic pump tubing can pass through a notch in the spring member, through the peristaltic pump and through a notch in a similar thin concave spring member mounted on an opposite side of said peristaltic pump so that the spring members prevent tube-stretching or deformation of the tubing. Numerous other embodiments are possible. All of the embodiments allow attaching a first and second notched spring-clamp or other tubing holder onto the input and output sides of a peristaltic pump frame; threading peristaltic pump tubing through a notch or other part in a first spring-clamp or tubing holder, through the peristaltic pump and through a notch or other part in a second spring-clamp or tubing holder. | 2011-11-24 |
20110286871 | SCROLL COMPRESSOR - A scroll compressor is provided that can reliably prevent a situation in which a product whose performance is degraded due to misassembly of a tip seal is shipped. In the scroll compressor, tip seals of different lengths are embedded in tip surfaces of a fixed spiral wrap of a fixed scroll and an orbiting spiral wrap of an orbiting scroll. Among the tip seals, thicknesses of the shorter tip seals are made thicker than thicknesses of the longer tip seals, and depths of seal grooves in which the tip seals are embedded, respectively, are formed to different depths in correspondence with the thicknesses of the respective tip seals. | 2011-11-24 |
20110286872 | Metering gear pump or segment, and metering gear pump assembly comprising a plurality of metering gear pumps or segments - A metering pump or segment, and a metering pump assembly comprising a plurality of the metering pumps or segments, are disclosed. The drive shaft assembly for driving the pump gears of each metering pump or segment is coaxially aligned with the longitudinal axis of the pump or segment, as is the fluid inlet supply path, whereby only three gears are required to comprise each metering pump or segment. The single drive shaft assembly is utilized to drive all of the metering pumps or segments comprising the metering pump assembly, and the different metering pumps or segments are fluidically connected together by means of a common fluid passageway. In addition, the different metering pumps or segments can be interchanged or exchanged so as to permit different metered fluid output volumes to be outputted at different predetermined locations. Also, different metering pumps or segments can be disposed or arranged such that their metered flow output volumes can effectively be added together so as to achieve additionally desired metered fluid output volumes which are different from that achieved from any single one metering pump or segment. | 2011-11-24 |
20110286873 | COMPOSITION OF PARTICULATE MATERIALS FOR FORMING SELF-LUBRICATING PRODUCTS IN SINTERED STEEL, PRODUCT IN SELF-LUBRICATING SINTERED STEEL AND PROCESS FOR OBTAINING SELF-LUBRICATING PRODUCTS IN SINTERED STEEL - The composition includes the iron as the main particulate metallic material; at least one particulate alloy element, with the function of hardening the ferrous structural matrix; and a precursor non-metallic particulate compound, generally a carbide or a carbonate, which is capable of generating, upon its dissociation during the sintering, graphite nodules, whose formation is facilitated: by the precursor compound itself when it includes a chemical element which stabilizes the iron alpha phase of the ferrous structural matrix; or by an additional alloy element included in the composition and which is defined by a chemical element that stabilizes the iron alpha phase during the sintering. The composition can be conformed by compaction or by powder injection molding. The process of the invention leads to obtaining products in self-lubricating sintered steel from said composition. | 2011-11-24 |
20110286874 | SINTERED 17-4PH STEEL PART AND METHOD FOR FORMING - A method of sintering a 17-4PH alloy powder and a sintered 17-4PH sintered part are disclosed. The part is formed by selective laser sintering a 17-4PH alloy powder and binder mixture to form a green part that is sintered to form a part having a substantially pure martensitic structure. The metal powder includes boron. The sintered part may be further processed by shot peening to improve crack resistance. | 2011-11-24 |
20110286875 | BEARING MATERIAL - A bearing material and a method for the manufacture of a bearing having a lining of the bearing material is described, the bearing material comprising: in wt %: 4-12 tin; 0.1-2 nickel; 1-6 bismuth; 0.01-less than 0.10 alumina; balance copper apart from incidental impurities. | 2011-11-24 |
20110286876 | THERMAL MANAGEMENT COMPOSITE MATERIALS - Graphite aluminum composites for use in thermal management applications, such as heat sinks, are manufactured using pressure molds. The materials may be mixed previous to insertion into the mold, or can be mixed within the mold. Further, graphitic particles, such as graphitic needle coke surfaces, can be coated with the aluminum before the mold process is performed. Further, ceramic sheets can be inserted into the mixture before the mold process is performed so that the molded material can then be sliced to provide a carbon aluminum composite plate with a ceramic sheet on one of its surfaces. | 2011-11-24 |
20110286877 | METAL POWDER - A process of using a molybdenum-containing binder alloy powder to produce a sintered hard metal based on a tungsten carbide includes providing a molybdenum-containing binder alloy powder with a FSSS value as determined in accordance with an ASTM B 330 standard of from 0.5 to 3 μm and comprising from 0.1 to 10% by weight of a molybdenum in at least one of an alloyed form and a prealloyed form, less than 60% by weight of an iron, up to 60% by weight of a cobalt, and from 10 to 60% by weight of a nickel. The molybdenum-containing binder alloy powder is incorporated into a hard metal. The hard metal is sintered so as to provide the liquid-phase-sintered hard metal based on a tungsten carbide. | 2011-11-24 |
20110286878 | METHOD FOR PRODUCTION OF NDFEBGA MAGNET AND NDFEBGA MAGNET MATERIAL - An NdFeBGa magnet material has a composition that is represented by the genera formula Nd | 2011-11-24 |
20110286879 | HIGH-Mn AUSTENITIC STAINLESS STEEL AND METAL PARTS FOR CLOTHING ORNAMENT - As a stainless steel for a metal part for clothing ornament capable of working into a complicated form part and having such nonmagnetic properties that the worked part can cope with the detection through needle detecting device is provided a high-Mn austenitic stainless steel having a chemical composition comprising C: 0.02-0.12 mass %, Si: 0.05-1.5 mass %, Mn: 10.0-22.0 mass %, S: not more than 0.03 mass %, Ni: 4.0-12.0 mass %, Cr: 14.0-25.0 mass % and N: 0.07-0.17 mass %, provided that these components are contained so that δ cal (mass %) represented by the following equation (1) is not more than 5.5 mass %: | 2011-11-24 |
20110286880 | HIGH STRENGTH Mg-Al-Sn-Ce AND HIGH STRENGTH/DUCTILITY Mg-Al-Sn-Y CAST ALLOYS - One exemplary embodiment includes a cast alloy including Al present in an amount of about 6.5 wt % to about 9.0 wt %; Sn present in an amount of about 1.0 wt % to about 3.0 wt %; Ce present in an amount of about 0 wt % to about 1.0 wt %; and, Mg comprising a balance of the alloy minus an amount of minor and trace elements wherein Mg is present at an amount of greater than about 85 wt %. | 2011-11-24 |
20110286881 | Methods for controlling and reducing pathogens, allergens odor-causing agents - Disclosed are methods for reducing and/or preventing infection and controlling and/or reducing the level of one or more pathogens, allergens and/or odor-causing agents. | 2011-11-24 |
20110286882 | Automated infection control surfaces - The invention is an automated infection control surface, which may be placed on the sole of a shoe or on the ground in the form of a floor mat/tile. The invention is composed of a series of individual light sources or LEDs (light emitting diodes) capable of emitting ultraviolet sanitizing light. When in the format of a shoe, there is an electronic switch in the form of a pressure sensor which is triggered when the operator's foot is planted within the shoe and standing firmly on the ground. When the pressure sensor is triggered the electrical current passes from the power source to the light sources or LEDs and illumination of sanitizing light occurs. When the shoe is lifted off the ground and when there is no weight or pressure within the shoe, the pressure sensor is turned off and the LEDs turn off. In this way the shoe is only capable of triggering UV microbicidal activity when the sole is flush to the ground, thus preventing inadvertent UV light scatter and potential skin and eye damage. The invention may also be composed in an array like fashion in the form of a floor mat or tile, such that the LEDs are oriented upwardly to shine towards the sole of the operator's shoe, but always concealed underneath the shoe. In either embodiment the LEDs are turned off when there is no weight on the sole of the shoe or floor mat/tile. Both embodiments of the invention could also be used simultaneously to provide maximum sterilization activity. | 2011-11-24 |
20110286883 | ULTRAVIOLET DISINFECTING DEVICE FOR FOOD AND BEVERAGE DISPENSERS - Disinfecting devices and related methods are provided that apply germicidal ultraviolet light to disinfect dispensing components of food and beverage dispensers. A disinfecting holster for a bar gun includes a support surface configured to interface with a bar gun to support the bar gun when stowed in the holster, a housing coupled with the support surface and surrounding a dispensing nozzle of the bar gun when the bar gun is stowed in the holster, and an ultraviolet light source configured to emit germicidal ultraviolet light onto the nozzle. The housing substantially contains the ultraviolet light within the housing during the application of the ultraviolet light to the dispensing nozzle. The ultraviolet light can be periodically applied to maintain the nozzle in a disinfected state. | 2011-11-24 |
20110286884 | HYDROGEN AND ELECTRICAL POWER GENERATOR - A device using needed hydrogen gas flow and electricity for operation obtained from a fuel cell power supply. Also, water generated by the fuel cell may be recycled for hydrogen generation which may be used by the device and in turn expanded by the fuel cell for further electrical power generation. The device may be a gas chromatograph, a fluid calibration mechanism, a flame ionization detector, or the like. | 2011-11-24 |
20110286885 | MICROFLUIDIC DEVICE HAVING NORMALLY OPEN TYPE MICROVALVE AND METHOD OF MANUFACTURING THE MICROFLUIDIC DEVICE - A microfluidic device includes a microvalve formed by disposing a thin elastic film and a valve seat in a microfluidic channel of the microfluidic device. The microvalve is a normally open type valve in which the elastic film does not contact the valve seat. According to the microvalve of the microfluidic device, an additional process for separating the elastic film from the valve seat is not required. Accordingly, the microfluidic device may have a relatively simple manufacturing process. Also, since an initialization operation to use the microfluidic device is not required, the flow of a fluid in the microfluidic device may be efficiently controlled without additional processing steps. | 2011-11-24 |
20110286886 | LABORATORY INSTRUMENT FOR THE PREPARATION OF SAMPLES - A laboratory instrument for the preparation of samples includes a base housing with a work compartment enclosed by protective walls, at least one multifunctional work head having the ability to turn about a rotary axis pivotally supported on the base housing. At least two defined functional positions that can be aligned with at least one container platform which is arranged in the work compartment. The first functional position contains a receiving device which serves to hold a dosage-dispensing device with free-flowing dosage material, and each of the other functional positions contains an additional device. At least one of the protective walls has a cutout opening, and the at least one multifunctional work head is arranged partially in the cutout, so that portions of the at least one multifunctional work head lies both inside and outside of the work compartment. | 2011-11-24 |
20110286887 | OPEN TYPE GROOVE CHANNEL CHIP - The present invention relates to an open-type groove channel chip. More particularly, the present invention relates to an open-type groove channel chip comprising a main body upper plate ( | 2011-11-24 |
20110286888 | Arrangement and method for electrochemically measuring biochemical reactions and method for producing the arrangement - The present invention relates to an arrangement, to a method for measuring with the arrangement and to a method for producing the arrangement. The arrangement is intended to electrochemically measure biochemical reactions and comprises a base plate, a sensor array situated on the latter, a coating of the base plate, and a sealing film with at least one recess. The recess is mechanically connected to the base plate and/or to the coating of the base plate and forms a flow cell above the sensor array. An inlet and an outlet of the flow cell are in the form of continuous recesses in the base plate. The active surfaces of the sensors are free of the coating and regions of the base plate adjacent to the sensors are covered by the coating. | 2011-11-24 |
20110286889 | Robust Low Resistance Vapor Sensor Materials - Compositions for sensor films used for detecting chemical analytes within sensors, such as polymer-absorption chemiresistors (i.e., conductometric sensors) are provided. Robust sensor film compositions that have low resistance, high conductivity, and greater temperature stability and sensitivity to chemical analytes are provided, as well as methods of making these sensor films. Such sensor film compositions include a matrix having a polymer resin and a plurality of conductive particles comprising an axial-geometry conductive particle. Exemplary axial-geometry conductive particles comprise graphene, such as a carbon nanotube. Blends of conductive particles are also contemplated, including blends of axial-geometry conductive particles, such as carbon nanotubes, and carbon black. | 2011-11-24 |
20110286890 | ELECTRICALLY HEATED EXHAUST GAS CONTROL APPARATUS - An electrically heated exhaust gas control apparatus includes: a hollow base member that has electroconductivity; a first insulation member that is disposed within the base member and that divides a vertically upper space and a vertically lower space from each other; a honeycomb catalyst formed in each of the vertically upper space and the vertically lower space; a pair of upper electrodes that heat the honeycomb catalyst in the vertically upper space and a pair of lower electrodes that heat the honeycomb catalyst in the vertically lower space; and a control portion that is able to stop electrifying the lower electrodes while continuing to electrify the upper electrodes. | 2011-11-24 |
20110286891 | SYSTEM FOR REDUCING ENVIRONMENTAL POLLUTANTS - The system for reducing environmental pollutants according to the present invention comprises: a first water immersion tank for producing strongly alkaline water by receiving a supply of bottom ash, which has been created by and has been accumulated at the bottom of a combustion furnace, and reacting it with water accommodated on its inside; an elimination reaction tank which is provided on a combustion pathway extending from the combustion furnace, and which internally accommodates the strongly alkaline water supplied from the first water immersion tank, and which also eliminates carbon-based compounds contained in exhaust gases which are discharged through the combustion pathway; a sludge-storage tank for receiving and storing sludge which has been produced as a consequence of the elimination reaction within the elimination reaction tank; a first aggregate storage tank for receiving and storing bottom-ash aggregate remaining within the first water immersion tank after the neutralisation which follows as a consequence of the production of the strongly alkaline water; and a second water immersion tank for supplying the elimination reaction tank with strongly alkaline water which is produced by reacting water, accommodated on its inside, with a supply of fly ash which has been generated by the combustion furnace and has accumulated in a dust-collecting device on the combustion pathway. | 2011-11-24 |
20110286892 | ELECTRO-KINETIC AIR MOVER WITH UPSTREAM FOCUS ELECTRODE SURFACES - An electro-kinetic air mover for creating an airflow using no moving parts. The electro-kinetic air mover includes an ion generator that has an electrode assembly including a first array of emitter electrodes, a second array of collector electrodes, and a high voltage generator. Preferably, a third or leading or focus electrode is located upstream of the first array of emitter electrodes, and/or a trailing electrode is located downstream of the second array of collector electrodes. The device can also include an interstitial electrode located between collector electrodes, an enhanced collector electrode with an integrally formed trailing end, and an enhanced emitter electrode with an enhanced length in order to increase emissivity. | 2011-11-24 |
20110286893 | PLASMA MICROREACTOR APPARATUS, STERILISATION UNIT AND ANALYSER - Apparatus for the production of a product gas (eg hydrogen and ozone) comprises: a supply of reactant gas (eg oxygen and steam) ( | 2011-11-24 |
20110286894 | System for Integrating Acid Gas Removal and Carbon Capture - In one embodiment, a system includes a hydrogen sulfide (H | 2011-11-24 |
20110286895 | MICROVALVE DEVICE AND METHOD OF MANUFACTURING THE SAME - A microvalve device comprises: a first substrate having a first surface, wherein at least one fluidic channel are formed into the first surface of the first substrate; and at least one valve seat are formed in the fluidic channel; a second substrate having a second surface, the second substrate comprising at least one air channel and at least one air chamber formed on the second surface of the second substrate, wherein the air chamber is connected to the air channel; and an elastic film interposed between the first substrate and the second substrate, where an upper portion of the valve seat is lower than the first surface of the first substrate. | 2011-11-24 |
20110286896 | Patterning Of Surfaces To Control The Storage, Mobility And Transport Of Liquids For Microfluidic Applications - Systems and methods to pattern surfaces to create regions of variable adhesive force on a superhydrophobic paper surface. By taking advantage of high surface energy sticky islands on a non-sticky superhydrophobic surface, microliter water drops can be registered or confined at specific locations; selected drops can then be transferred to another patterned substrate and the drops mixed and/or allowed to react without the need for pipettes or other fluid transfer tool. | 2011-11-24 |
20110286897 | Microtiter plate - Microtiter plate made of plastic, having a plurality of wells in a plate which has at least one break line that divides the plate into various segments. The break line includes a joint line which is formed by molding together various segments of the plate. | 2011-11-24 |
20110286898 | PROCESS FOR RECOVERING RUTHENIUM FROM USED RUTHENIUM OXIDE-COMPRISING CATALYSTS - The invention relates to a process for recovering ruthenium from a used ruthenium-comprising catalyst which comprises ruthenium as ruthenium oxide on a support material which is not readily soluble in mineral acid, which comprises the steps: | 2011-11-24 |
20110286899 | APPARATUS AND METHOD OF CLEANING GAS IN BLOW MOULDING MACHINES - An apparatus ( | 2011-11-24 |
20110286900 | PGM-Zoned Catalyst for Selective Oxidation of Ammonia in Diesel Systems - Platinum group metal zoned ammonia oxidation catalytic articles and methods of making are described. Also described are emissions treatment systems and methods of treating an exhaust stream containing ammonia using a platinum group metal zoned ammonia oxidation catalytic article. | 2011-11-24 |
20110286901 | FLUIDIZED BED WATER GAS SHIFT MEMBRANE FOR SIMULTANEOUS CO2 SEPARATION AND CO2 SEPARATION METHOD USING THE SAME - Disclosed are a fluidized bed water gas shift membrane reactor and a method for separating carbon dioxide using the same. More specifically, disclosed are a fluidized bed water gas shift membrane reactor provided on the back of a gasification reactor to produce a synthetic gas consisting of hydrogen and carbon monoxide by reaction of a solid hydrocarbon with water or oxygen, wherein the carbon monoxide present in an amount of 40 to 70 vol % in the synthesis gas reacts with steam in the presence of a catalyst to produce a mix gas of hydrogen and carbon dioxide, and the hydrogen is selectively isolated from the mix gas through a Pb—Cu shift membrane to increase the concentration of carbon dioxide present in the mix gas and separate the carbon dioxide, and a method for separating carbon dioxide using the same. | 2011-11-24 |
20110286902 | CARBONATION CALCINATION REACTION PROCESS FOR CO2 CAPTURE USING A HIGHLY REGENERABLE SORBENT - A process for the efficient capture of CO | 2011-11-24 |
20110286903 | CATALYTIC REDUCTION OF NOx - A system for NO | 2011-11-24 |
20110286904 | APPARATUS AND PROCESS FOR METAL OXIDES AND METAL NANOPARTICLES SYNTHESIS - The present invention provides an approach to control the generation and grow of nanocrystal with membrane diffusion method and related apparatuses to produce inorganic oxide nanopowders and metal nanoparticles. With this method, the size and size distribution of inorganic oxide nanopowders and metal nanoparticles can be tuned. It overcomes the shortcomings possessed by the common chemical and physical method of preparing nanoparticles. | 2011-11-24 |
20110286905 | PROCESSES FOR PRODUCING PHOSPHORUS TETRAFLUORIDE AND PHOSPHATE HEXAFLUORIDE - An object the invention is to provide a phosphorus pentafluoride producing process wherein phosphorus pentafluoride is separated/extracted from a pentavalent phosphorus compound or a solution thereof, or a composition obtained by allowing the pentavalent phosphorus compound or the solution thereof to react with hydrogen fluoride, thereby producing phosphorus pentafluoride; and a phosphate hexafluoride producing process wherein the resultant phosphorus pentafluoride is used as raw material to produce a phosphate hexafluoride high in purity. The present invention relates to a process for producing phosphorus pentafluoride, wherein a carrier gas is brought into contact with either of the following one: a pentavalent phosphorus compound, a solution thereof, or a solution in which a composition obtained by allowing the pentavalent phosphorus compound or the solution thereof to react with hydrogen fluoride is dissolved, thereby a phosphorus pentafluoride is extracted into the career gas. | 2011-11-24 |
20110286906 | Flowable Chips and Methods for the Preparation and Use of Same, and Apparatus for Use in the Methods - A method for recharging a crucible with polycrystalline silicon comprises adding flowable chips to a crucible used in a Czochralski-type process. Flowable chips are polycrystalline silicon particles made from polycrystalline silicon prepared by a chemical vapor deposition process, and flowable chips have a controlled particle size distribution, generally nonspherical morphology, low levels of bulk impurities, and low levels of surface impurities. Flowable chips can be added to the crucible using conventional feeder equipment, such as vibration feeder systems and canister feeder systems. | 2011-11-24 |
20110286907 | AMMONIA SYNTHESIS PROCESS - The invention provides a process for efficient synthesis of ammonia. The process includes a water-splitting step in which water is decomposed to obtain a first source gas comprising hydrogen and oxygen, a first oxygen removal step in which the oxygen contained in the first source gas is at least partially separated and removed by an oxygen separating membrane or hydrogen separating membrane to obtain a second source gas having a lower oxygen concentration than the first source gas, a second oxygen removal step in which the oxygen in the second source gas is reacted with hydrogen to produce water for removal, or is adsorbed onto an adsorption medium for removal, to obtain a third source gas having a lower oxygen concentration than the second source gas, and an ammonia synthesis step in which the hydrogen in the third source gas is reacted with nitrogen to synthesize ammonia. | 2011-11-24 |
20110286908 | High Concentration NO2 Generating System and Method for Generating High Concentration NO2 Using the Generating System - A high concentration NO | 2011-11-24 |
20110286909 | Generation Of CO Using Off-Gas As Source - A method for generating CO using an off-gas as a source is provided. This method includes providing an off-gas feed stream, wherein said off-gas feed stream comprises CO | 2011-11-24 |
20110286910 | Method Of Preparing Carbon Substrate For Gas Diffusion Layer Of Polymer Electrolyte Fuel Cell, Carbon Substrate Prepared By Using The Method, And System For Manufacturing The Same - A carbon substrate, method, and a system for manufacturing the same. The method includes forming an oxidized carbon precursor fiber preweb comprising oxidized carbon precursor staple fibers and binder staple fibers; impregnating the oxidized carbon precursor fiber preweb with a slurry including a thermosetting resin and carbonaceous fillers and drying the resulting preweb to obtain an oxidized carbon precursor fiber web; applying heat and pressure to the oxidized and impregnated carbon precursor fiber web, to cure the thermosetting resin and press the oxidized carbon precursor fiber web; and heating the oxidized carbon precursor fiber web in an inert atmosphere, thereby stabilizing and carbonizing the oxidized carbon precursor staple fibers to obtain a carbon substrate. The present invention may utilize a combination of carbon precursor staple fibers in an oxidized form with low ductility and high stiffness; and binder staple fibers composed of a polymer resin. | 2011-11-24 |
20110286911 | HYDROGEN FLUORIDE PURIFICATION METHOD - To provide a novel method for purifying hydrogen fluoride, capable of efficiently reducing the content of arsenic in hydrogen fluoride. | 2011-11-24 |
20110286912 | CATHODE ACTIVE MATERIAL (HIGHER OXIDES OF SILVER) - The present invention provides novel cathodes having a reduced resistivity and electrochemical cells using these cathodes. Furthermore, this invention also presents methods of manufacturing novel electrochemical cells and novel cathodes. | 2011-11-24 |
20110286913 | METHOD, DEVICE AND FUEL FOR HYDROGEN GENERATION - A method and a device for generating of hydrogen are provided with which an instantaneous release of hydrogen in considerable amounts is possible. The method comprises a one or two step mixing including injecting the fuel and an activator fluid into a reaction chamber. The device is adapted to be operated with such a method. Further, a fuel suitable for the use with such a method is provided, the fuel being based on a dry metal hydride or a dry metal borohydride being dispersed in a non-aqueous dispersion medium. Moreover, a method for (re-) fuelling the hydrogen generating device at a service station and a method for supplying a service station with fuel are provided. | 2011-11-24 |
20110286914 | NOVEL METAL-CONTAINING ZEOLITE BETA FOR NOx REDUCTION AND METHODS OF MAKING THE SAME - There is disclosed an organic-free, metal-containing zeolite Beta with a silica-to-alumina ratio (SAR) ranging from 5 and 20, and a metal content of at least 0.5 wt. %. There is also disclosed a method of making such a zeolite Beta without organic structure directing agent (SDA). The metal, which may comprise Fe or Cu, can be found in amounts ranging from 1-10 wt. %. A method of selective catalytic reduction of nitrogen oxides in exhaust gases using the disclosed zeolite is also disclosed. | 2011-11-24 |
20110286915 | Nanocarriers for Drug Delivery - The present invention provides a nanocarrier having an interior and an exterior, the nanocarrier comprising at least one conjugate, wherein each conjugate includes a polyethylene glycol (PEG) polymer. Each conjugate also includes at least two amphiphilic compounds having both a hydrophilic face and a hydrophobic face. In addition, each conjugate includes an oligomer, wherein at least 2 of the amphiphilic compounds are covalently attached to the oligomer which is covalently attached to the PEG. The nanocarrier is such that each conjugate self-assembles in an aqueous solvent to form the nanocarrier such that a hydrophobic pocket is formed in the interior of the nanocarrier by the orientation of the hydrophobic face of each amphiphilic compound towards each other, and wherein the PEG of each conjugate self-assembles on the exterior of the nanocarrier. | 2011-11-24 |
20110286916 | GENERATION AND CHARACTERIZATION OF ANTI-NOTCH ANTIBODIES FOR THERAPEUTIC AND DIAGNOSTIC USE - The present invention relates to mammalian antibodies, preferably fully human monoclonal antibodies and antigen-binding portions thereof that specifically bind to a cell surface receptor, wherein the receptor protein is a Notch1 receptor protein. Some of the disclosed antibodies bind Notch1 to the exclusion of other members of the Notch receptor family, while other antibodies bind Notch 1 and Notch3. Nucleic acid molecules encoding the Notch antibodies as well as methods of use thereof are also disclosed. Also included are pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for treatment and diagnosis of pathological hyperproliferative oncogenic disorders associated with expression of Notch1 or Notch3 including aberrant activation of each of these receptors. | 2011-11-24 |
20110286917 | Novel, Prostate-Specific Gene for Diagnosis, Prognosis and Management of Prostate Cancer - Disclosed are nucleic acid and amino acid sequences encoded by a novel, prostate specific gene (UC41) and diagnostic techniques for the detection of human prostate cancer utilizing such nucleic acid and amino acid sequences. Genetic probes and methods useful in monitoring the progression and diagnosis of prostate cancer are described. Methods of treatment for prostate cancer utilizing antisense constructs or antibodies specific for UC41 gene products are also described. | 2011-11-24 |
20110286918 | IMMUNOTHERAPY OF AUTOIMMUNE DISORDERS USING ANTIBODIES WHICH TARGET B-CELLS - Antibodies that bind with a B-cell antigen provide an effective means to treat autoimmune disorders. Antibodies and fragments, which may be conjugated or naked, are used alone or in multimodal therapies. The antibodies may be bispecific antibodies which may be produced recombinantly as fusion proteins, or as hybrid, polyspecific antibodies. | 2011-11-24 |
20110286919 | CONJUGATES OF NOSCAPINE AND FOLIC ACID AND THEIR USE IN TREATING CANCER - The present invention is directed to compounds which are conjugates of two non-toxic natural products, noscapine (and various noscapine analogs) and folic acid (and various folic acid analogs), where the folic acid is conjugated to noscapine or the noscapine analog at the 9-position on the isoquinoline ring on the noscapine framework. Pharmaceutical compositions including the compounds, and methods of treating various tumors using the compounds and compositions, are also disclosed. The conjugates are particularly useful for treating cancers which overexpress the Folate Receptor α (FRa) receptor. | 2011-11-24 |
20110286920 | COMPLEX OF BIFUNCTIONAL CHELATING AGENT AND MANNOSYL HUMAN SERUM ALBUMIN - The present invention is about bifunctional chelating agents (BCA) conjugated mannosyl human serum albumin (MSA) and its radioisotope labeled compounds for imaging immune system such as macrophages, Kupffer cells, reticuloendothelial system (RES), and lymphatic system. The present invention comprises BCA-MSA conjugates, their radiolabeled compounds, and kits for radiolabeing. The present invention improved radiolabeling procedure, showed higher lymphatic system uptake, and enabled image by positron emission tomography (PET). | 2011-11-24 |
20110286921 | 18F-LABELLED FOLATES AS PET RADIOTRACERS - The present invention is directed towards new | 2011-11-24 |
20110286922 | IMAGING AND RADIOTHERAPY METHODS - The present invention relates to in vivo imaging and radiotherapeutic methods and agents which target the enzyme aldehyde dehydrogenase (ALDH) and that are suitable for the in vivo imaging of tumours and treatment of cancer. | 2011-11-24 |
20110286923 | NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES - Conjugates of a polymer having attached thereto an angiogenesis targeting moiety and a therapeutically active agent such as an anti-cancer agent or anti-angiogenesis agent, and processes of preparing same are disclosed. | 2011-11-24 |
20110286924 | NOVEL HUMAN ENDOGENOUS RETROVIRAL ERV3 VARIANT AND USES THEREOF IN THE DIAGNOSING OVARIAN CANCER - The present invention relates to polynucleotide and polypeptide sequences of a novel human endogenous retroviral ERV3 variant which is differentially expressed in ovarian cancer cells when compared to normal cells. The present invention more particularly relates to the use of these polynucleotide and polypeptide in the diagnosis, prognosis or treatment of cancer and in the detection of cancer cells. | 2011-11-24 |
20110286925 | Embolizing Sclerosing Hydrogel - A sclerosing embolizing hydrogel comprising from about 0.1% by weight to about 4.0% by weight of chitosan; from about 0.01M to about 1M of hydrochloric acid; from 0% by volume to about 40% by volume of iopamidol; from 0.5% by weight to about 25% by weight of β-glycerophosphate disodium salt; and from about 0.05% by weight to about 4% by weight of sodium tetradecyl sulphate. Also a kit for synthesizing the hydrogel and a method using the hydrogel to treat a vascular defect in a subject. | 2011-11-24 |
20110286926 | DEGRADABLE HYDROGEL COMPOSITIONS AND METHODS - This invention concerns an in situ biodegradable hydrogel drug delivery system in which the components are assembled in a manner that provides a mechanism for the timed cleavage of a particular amide bond in a covalently linked active agent or of the hydrogel structure. | 2011-11-24 |
20110286927 | ATF4 Inhibitors and Their Use for Neural Protection, Repair, Regeneration, and Plasticity - In one aspect, the invention relates to a method for identifying a drug candidate with activity as a neuroprotective agent. The method includes determining whether a compound reduces ATF4 activity; and identifying the compound that reduces ATF4 activity as a drug candidate. | 2011-11-24 |
20110286928 | Methods and compositions for inhibition of BCL6 repression - Provided are peptides or mimetics that block corepressor binding to a BCL6 lateral groove. Also provided are methods or blocking corepressor binding to the BCL6 lateral groove. Additionally, methods of inhibiting BCL6 repression in a mammalian cell, and methods of treating a mammal with cancer are provided. | 2011-11-24 |
20110286929 | MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS - The invention provides compositions and methods for therapeutic and diagnostic applications. | 2011-11-24 |
20110286930 | METHODS OF IDENTIFYING MODULATORS OF THE PP2A B56 BETA REGULATORY SUBUNIT - The present invention is based at least in part on the discovery that the PP2A B56 regulatory subunit plays a role in regulating insulin signaling by directly regulating phosphorylation of AKT-I. Accordingly, the present invention features methods of identifying modulators of the PP2A B56 regulatory subunit in assays featuring organisms and/or cells. Further featured are therapeutic methods for the use of PP2A B56 regulatory subunit modulators to enhance longevity, to prevent or treat cancer, to prevent or reduce obesity and to prevent or treat type II diabetes. | 2011-11-24 |
20110286931 | CARDIAC ARRHYTHMIA TREATMENT METHODS AND BIOLOGICAL PACEMAKER - Disclosed are methods of preventing or treating cardiac arrhythmia. In one embodiment, the methods include administering to an amount of at least one polynucleotide that modulates an electrical property of the heart. The methods have a wide variety of important uses including treating cardiac arrhythmia. Also disclosed are methods and systems for modulating electrical behavior of cardiac cells. Preferred methods include administering a polynucleotide or cell-based composition that can modulate cardiac contraction to desired levels, e.g., the administered composition functions as a biological pacemaker. | 2011-11-24 |
20110286932 | OPTICAL METHOD FOR THE DETECTION OF ALZHEIMER'S DISEASE - The present subject matter relates to a non-invasive optical imaging method for monitoring early pathological events specific to Alzheimer's disease (AD), such as the development, amount and location of amyloid plaques. The ability to monitor such events provides a basis for, among other things, AD diagnosis, prognosis and assessment of potential therapies. In addition, the present subject matter introduces novel methods for treating AD and retinal ailments associated with AD. Aβ-plaque detection in living brains is extremely limited, especially at high resolution; therefore the present invention is based on studies focusing on the eyes as an alternative to brain-derived tissue that can be imaged directly, repetitively and non-invasively. | 2011-11-24 |