48th week of 2015 patent applcation highlights part 25 |
Patent application number | Title | Published |
20150337324 | METHOD FOR REGULATING EXPRESSION OF SPECIFIC PROTEIN USING CYTOKININ-RESPONSIVE TRANSCRIPTION FACTOR, ISOPRENOID-PRODUCING PLANT HAVING GENE ENCODING CYTOKININ-RESPONSIVE TRANSCRIPTION FACTOR INTRODUCED THEREIN, AND METHOD FOR PRODUCING POLYISOPRENOID USING SAID ISOPRENOID-PRODUCING PLANT - The present invention provides a method for enhancing the overall pathway of polyisoprenoid biosynthesis. The present invention further provides an isoprenoid-producing plant having an overall enhanced pathway of polyisoprenoid biosynthesis, and a method of producing a polyisoprenoid using such an isoprenoid-producing plant. The present invention relates to a method of regulating by a cytokinin-responsive transcription factor the expression of at least one protein selected from the group consisting of hydroxymethylglutaryl-CoA reductase, isopentenyl diphosphate isomerase, cis-prenyltransferase, and small rubber particle protein. | 2015-11-26 |
20150337325 | GENE CAPABLE OF IMPROVING MATERIAL PRODUCTIVITY IN SEED AND METHOD FOR USE THEREOF - An object of the present invention is to search for a gene having a novel function that can cause an increase or decrease in material productivity, and particularly, fat and oil content. In the present invention, a chimeric protein obtained by fusing a transcription factor consisting of a protein comprising an amino acid sequence shown in any of the even-numbered SEQ ID NOS: 1 to 158 and a functional peptide capable of converting an arbitrary transcription factor into a transcriptional repressor is expressed in a plant. | 2015-11-26 |
20150337326 | PLANTS HAVING ENHANCED YIELD-RELATED TRAITS AND METHOD FOR MAKING THE SAME - The present invention relates generally to the field of molecular biology and concerns a method for enhancing various economically important yield-related traits in plants. More specifically, the present invention concerns a method for enhancing yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding an OsRSZ33 RRM polypeptide, a growth-related protein (GRP) having at least 25% amino acid sequence identity to SEQ ID NO: 251, or a ZPR polypeptide. The present invention also concerns plants having modulated expression of a nucleic acid encoding an OsRSZ33 RRM polypeptide, a growth-related polypeptide as defined herein, or a ZPR polypeptide, which plants have enhanced yield-related traits relative to control plants. The invention also provides unknown OsRSZ33 RRM-encoding nucleic acids, GRP-encoding nucleic acids, or a ZPR polypeptide, and constructs comprising the same, useful in performing the methods of the invention. | 2015-11-26 |
20150337327 | Negative Regulator of the Abiotic Stress Response - A small heat shock protein, AsHSP17, that has been cloned from creeping bentgrass ( | 2015-11-26 |
20150337328 | Methods and Constructs for Conferring Enhanced Abiotic Stress Resistance in Plants - A conserved monocot-specific miRNA, miR528, is described that can be utilized for mediating multiple stress responses and/or mediating morphological aspects of plant development. Also described are transgenic plant cells, plant parts such as seeds and plants as well as progeny of the seeds and plants that include a recombinant polynucleotide including a nucleic acid molecule encoding miR528. Also disclosed are targets of miR528, all of which appear to function in oxidation-reduction processes. | 2015-11-26 |
20150337329 | GENE SEQUENCES AND USES THEREOF IN PLANTS - This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits. | 2015-11-26 |
20150337330 | Management of Corn Rootworm and Other Insect Pests - Trap and/or refuge crops and methods of use in managing corn rootworm and other insect pests of maize are provided. Some methods involve using trap crops comprising plants with enhanced susceptibility to one or more insect pests to lure and kill insect pests. Other methods involve using refuge crops comprising plants with enhanced susceptibility to one or more insect pests to monitor insect pest populations in an area or to promote mating between insecticide resistant and insecticide non-resistant insects. | 2015-11-26 |
20150337331 | NOVEL EXPRESSION VECTOR - Disclosed are a novel expression vector for efficient expression of recombinant proteins in mammalian cells, a mammalian cell transformed with the vector, and a method for production of the mammalian cell. The expression vector is an expression vector for expression of a mammalian protein and includes a gene expression regulatory site, and a gene encoding the protein downstream thereof, and an internal ribosome entry site further downstream thereof, and a gene encoding a glutamine synthetase further downstream thereof, and a dihydrofolate reductase gene downstream of either the same gene expression regulatory site or another gene expression regulatory site in addition to the former. | 2015-11-26 |
20150337332 | Methods and Compositions to Modulate RNA Processing - The present disclosure provides methods and compositions to selectively modulate RNA processing. The methods and compositions selectively enhance or repress RNA processing by up- or down-regulating Drosha expression and/or by providing RNA sequences with mis-matches introduced or removed 5 and/or 9-12 nucleotide positions from the Drosha cutting site. Therapeutic uses of the methods and compositions are also described. | 2015-11-26 |
20150337333 | REGULATORY NUCLEIC ACID ELEMENTS - The invention relates to DNA-sequences, especially transcription- or expression-enhancing elements (TE elements) and their use on an expression vector in conjunction with an enhancer, a promoter, a product gene and a selectable marker. | 2015-11-26 |
20150337334 | METHOD FOR PRODUCTION OF REPROGRAMMED CELL USING CHROMOSOMALLY UNINTEGRATED VIRUS VECTOR - An objective of the present invention is to provide vectors for conveniently and efficiently producing ES-like cells in which foreign genes are not integrated into the chromosome. The present inventors discovered methods for producing ES-like cells from somatic cells using chromosomally non-integrating viral vectors. Since no foreign gene is integrated into the chromosome of the produced ES-like cells, they are advantageous in tests and research, and immunological rejection and ethical problems can be avoided in disease treatments. | 2015-11-26 |
20150337335 | Rationally-Designed Single-Chain Meganucleases With Non-Palindromic Recognition Sequences - Disclosed are rationally-designed, non-naturally-occurring meganucleases in which a pair of enzyme subunits having specificity for different recognition sequence half-sites are joined into a single polypeptide to form a functional heterodimer with a non-palindromic recognition sequence. The invention also relates to methods of producing such meganucleases, and methods of producing recombinant nucleic acids and organisms using such meganucleases. | 2015-11-26 |
20150337336 | ENZYMES AND METHODS FOR STYRENE SYNTHESIS - The subject technology generally relates to biosynthesis of styrene. Certain embodiments of the subject technology is based, in part, on the recognition that phenylalanine can be converted to styrene by a two-step pathway of deamination and decarboxylation, with trans-cinnamic acid (tCA) as the intermediate. Two types of enzymes are directly involved in this process, phenylalanine ammonia lyase (PAL), which converts phenylalanine to tCA, and cinnamic acid decarboxylase, which coverts tCA to styrene. Host cells expressing these two types of enzymes can be cultured in bioreactor to produce styrene from renewable substrates such as glucose. | 2015-11-26 |
20150337337 | PHYTASE IN BIOGAS PRODUCTION - The invention relates to a process for the production of biogas from organic material comprising: treating said organic material with an enzyme composition comprising a phytase, preferably a phytase and a cellulase and/or hemicellulase, and digesting the enzyme treated organic material to form biogas, and further to the use of an enzyme composition comprising a phytase to increase the digestibility of proteins and polysaccharides by microbes present in a process suitable for the conversion of organic material into biogas; the use of an enzyme composition comprising a phytase to increase the availability of minerals in a process suitable for the conversion of organic material into biogas; and the use of an enzyme composition comprising a phytase to reduce precipitation of salts on hardware such as (metal) surfaces and in lines and pumps in a process suitable for the conversion of organic material into biogas. | 2015-11-26 |
20150337338 | RECOMBINANT CELL AND METHOD FOR PRODUCING ISOPRENE - An object of the present invention is to provide a series of techniques for producing isoprene from methanol or the like. Provided is a recombinant cell prepared by introducing a gene encoding isoprene synthase, into a host cell which is a methylotroph, wherein the gene is expressed in the host cell, and the recombinant cell is capable of producing isoprene from at least one C1 compound selected from the group consisting of methane, methanol, methylamine, formic acid, formaldehyde, and formamide. Preferably, it has at least one C1 carbon assimilating pathway selected from the group consisting of a serine pathway, a ribulose monophosphate pathway, and a xylulose monophosphate pathway as a fixing pathway of formaldehyde. Also provided is a method for producing isoprene using the recombinant cell. | 2015-11-26 |
20150337339 | Production Method of Enzyme Containing Antrodia Cinnamomea Component - A production method of enzyme containing | 2015-11-26 |
20150337340 | PENTOSE FERMENTATION BY A RECOMBINANT MICROORGANISM - The present invention provides methods and compositions suitable for use in the isomerization of xylose to xylulose, as well as methods and compositions suitable for use in the conversion of xylose to xylitol and xylulose, including nucleic acid constructs, recombinant fungal host cells, and related materials. | 2015-11-26 |
20150337341 | FERMENTATION PROCESS FOR THE PRODUCTION AND CONTROL OF PYRUVATE-DERIVED PRODUCTS - A process for producing and controlling pyruvate derived products during the fermentation of a CO containing substrate by an acetogenic carboxydotrophic microorganism has been developed. The process involves increasing the concentration of at least one nutrient selected from the group consisting of vitamin B1, vitamin B5, vitamin B7 and mixtures thereof above the cellular requirement of the microorganism. When the concentration is increased, the production of 2,3-butanediol (2,3-BDO) increases whereas the production of the other metabolites is virtually unchanged. The effect is reversible so that when the concentration is decreased, the production of 2,3-BDO is also decreased. This allows one to control the ratio of ethanol:2,3-BDO to a desired value which can vary from about 4:1 to about 1:2. | 2015-11-26 |
20150337342 | BIOSYNTHETIC PATHWAYS AND METHODS - This disclosure describes a recombinant microbial cells and methods of making and using such recombinant microbial cells. Generally, the recombinant cells may be modified to exhibit increased biosynthesis of a TCA derivative compared to a wild-type control. In some embodiments, the TCA derivative can include 1,4-butanediol. In various embodiments, the microbial cell is a fungal cell or a bacterial cell. In some embodiments, the increased biosynthesis of the TCA derivative can include an increase in xylose dehydrogenase activity, xylonolactonase activity, xylonate dehydratase activity, or 2-keto-3-deoxyaldonic acid dehydratase activity. | 2015-11-26 |
20150337343 | A FERMENTATION PROCESS - This invention relates generally to method for producing products, particularly alcohols, by microbial fermentation. In particular, the invention relates to methods for increasing the efficiency of the fermentation, by providing a method for treating the used fermentation broth to produce a treated permeate which is then passed back to the bioreactor. The invention provides a method whereby at least one treatment step used to treat the permeated, produces a gaseous product which is then used in one or more stages of the fermentation process. | 2015-11-26 |
20150337344 | METHOD FOR PRODUCING POLYHYDROXYALKANOATES BY MICROORGANISMS - Method for simultaneous selection and maintenance of a selected microbial consortium for polyhydroxyalkanoates (PHA) production in only one step, said microbial consortium being fed with at least one readily biodegradable carbon substrate, comprising a first step of aerobic cultivation of said microbial consortium in a mixed biological reactor. According to the invention, the specific cell growth rate μl of said microbial consortium is fixed at a target value, in said first step of aerobic cultivation and in that said first step of aerobic cultivation is performed under nutrient limitation such as the readily biodegradable carbon substrate uptake rate qS | 2015-11-26 |
20150337345 | METHODS OF OIL PRODUCTION IN MICROORGANISMS - Provided herein are methods for producing one or more polyunsaturated fatty acids. The methods include the steps of providing a microorganism capable of producing polyunsaturated fatty acids, providing a medium comprising a high concentration of one or more carbon sources, low pH, or both, and culturing the microorganism in the medium under sufficient conditions to produce the one or more polyunsaturated fatty acids. Also provided are methods of culturing one or more microorganisms. The methods include culturing the microorganisms in a medium comprising a first amount of one or more carbon sources at a first concentration level, monitoring a carbon source concentration until the carbon source concentration is reduced below the first concentration level, and adding to the medium a second amount of one or more carbon sources to increase the carbon source concentration to a second concentration level. | 2015-11-26 |
20150337346 | ASPARAGINIC ACID KINASE III MUTANT AND HOST CELLS AND USE THEREOF - Provided in the present invention is an asparaginic acid kinase, and the 340 | 2015-11-26 |
20150337347 | Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same - The present invention relates to polypeptides having cellulolytic enhancing activity, catalytic domains, and carbohydrate binding domains, and polynucleotides encoding the polypeptides, catalytic domains, and carbohydrate binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, and carbohydrate binding domains. | 2015-11-26 |
20150337348 | Enzymatic Synthesis of L-Nucleic Acids - The present invention is related to a method for adding one or more L-nucleotides to the 3′ end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising an enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3′ end of the first L-nucleic acid. | 2015-11-26 |
20150337349 | Microbiome Modulation Index - The disclosure provides methods and systems for characterizing the effects of an agent on one or more microbial communities. | 2015-11-26 |
20150337350 | AUTOMATED VIABILITY TESTING SYSTEM - The invention provides an automated device for accessing the viability of a wide range of organisms based on the metabolic production of fluorescent products from non-fluorescent substrates. Also provide are methods for detecting contaminants in a fluid and measuring the viability of organisms in a fluid or liquid. Components of the invention include the incorporation of a reusable filter to concentrate the organisms, the back flush of the filter to collect the organisms for assay, and the addition of the substrate in a fluorescent detection chamber to detect the enzymatic activity produced by viable organisms to detect the presence of such organisms. | 2015-11-26 |
20150337351 | METHODS OF MICROORGANISM IMMOBILIZATION - The present disclosure is related to methods for immobilizing microorganisms to produce an immobilized microorganism sample for detection with a detection system. Compositions for immobilizing microorganisms are also disclosed. | 2015-11-26 |
20150337352 | RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING SYSTEM BASED ON BACTERIAL IMMOBILIZATION USING GELLING AGENT, ANTIBIOTIC DIFFUSION AND TRACKING OF SINGLE BACTERIAL CELLS - A testing method is disclosed. The testing method includes: providing a mixture solution of a gelling agent and a microbe to a gelling device; solidifying the mixture solution to form a solid thin film in which the microbe is immobilized; supplying a bioactive agent to the solid thin film and allowing the bioactive agent to diffuse into the solid thin film; and imaging the individual responses of the single microbial cells to the bioactive agent, and determining the minimum inhibitory concentration (MIC) of the bioactive agent based on the analysis of the images to obtain AST results. | 2015-11-26 |
20150337353 | RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING SYSTEM BASED ON BACTERIAL IMMOBILIZATION USING GELLING AGENT, ANTIBIOTIC DIFFUSION AND TRACKING OF SINGLE BACTERIAL CELLS - A testing method is disclosed. The testing method includes: providing a mixture solution of a gelling agent and a microbe to a gelling device; solidifying the mixture solution to form a solid thin film in which the microbe is immobilized; supplying a bioactive agent to the solid thin film and allowing the bioactive agent to diffuse into the solid thin film; and imaging the individual responses of the single microbial cells to the bioactive agent, and determining the minimum inhibitory concentration (MIC) of the bioactive agent based on the analysis of the images to obtain AST results. | 2015-11-26 |
20150337354 | BIOLOGICAL STERILIZATION INDICATOR DEVICES AND METHODS OF USE - A biological sterilization indicator device is provided. The device comprises a body, a plurality of test microorganisms, and an oxygen-modulated first fluorescent sensor. The body comprises a first layer attached to a second layer, forming at least one isolatable microchamber and at least one primary passageway that provides fluidic communication between ambience and the at least one microchamber. The microchamber has an isolated volume of about 0.5 microliters to about 9.5 microliters. The plurality of test microorganisms and the oxygen-modulated first fluorescent sensor are disposed in the microchamber. A method of using the device to determine the effectiveness of a sterilization process is also provided. | 2015-11-26 |
20150337355 | CELL-SPREADING DEVICE AND METHOD FOR DETECTING RARE CELL - A cell-spreading device may include a microchamber chip having a microchamber capable of enclosing and retaining a cell, a channel-forming frame united with the microchamber chip to form a channel on the microchamber, an inlet provided in the channel-forming frame to allow a cell suspension to flow into the channel, and an outlet provided in the channel-forming frame to allow the cell suspension, which has been allowed to flow into the channel through the inlet, to flow out from the channel. When an aperture of the microchamber is projected perpendicularly to a longitudinal width of the microchamber chip, the void ratio that is a ratio of the sum total of voids to the longitudinal width is not more than 5%, the void being a length of a portion where the projected aperture of the microchamber is not present against the longitudinal width. | 2015-11-26 |
20150337356 | METHOD FOR IN VITRO DETECTION AND MONITORING OF A DISEASE BY MEASURING DISEASE-ASSOCIATED PROTEASE ACTIVITY IN EXTRACELLULAR VESICLES - The present invention relates to a method for in vitro detection and/or monitoring of a disease in a sample, based on measurement of enzymatic activity of proteases activated and secreted upon disease development, to modified peptides used for the enzymatic detection of the proteases, the use of the peptides, a kit comprising such peptides and the use of ADAM-protease activity as a surrogate marker for disease burden and activity in infectious, inflammatory, and malignant diseases, such as HIV infection and melanoma. | 2015-11-26 |
20150337357 | USE OF RAPID ONSITE BACTERIA TEST FOR OIL AND GAS APPLICATIONS - A method for onsite bacteria testing for oil and gas applications including collecting at least one component of a wellbore fluid; exposing at least one contaminant in the at least one component to at least one substrate that produces a detectable moiety; and performing a quantitative or qualitative detection of the detectable moiety. | 2015-11-26 |
20150337358 | APPARATUS AND METHODS FOR DETECTING ATP IN A LIQUID SAMPLE - Apparatuses and kits for the detection of ATP in a liquid sample are provided. The apparatuses and kits comprise a liquid reagent composition comprising luciferin and a sampling device having a sampling portion and a handling portion. The sampling portion comprises a fibrous or a foam material and is adapted to acquire and releasably retain a predetermined volume of a liquid sample or a sample of residue from a surface. The sampling device comprises a dry coating or a liquid coating, the coating including an effective amount of a pH-adjusting reagent that, when contacted with a liquid reagent composition having a pH 6.8 or lower, changes the pH of the liquid reagent composition to 6.9 or higher. Methods of use of the apparatus or kit are also provided. | 2015-11-26 |
20150337359 | LUCIFERASE-BASED ASSAYS - A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minimize interference by at least about 10% relative to an assay not having tolerance enhancement agent. | 2015-11-26 |
20150337360 | DEVICE FOR GENOTYPIC ANALYSIS AND METHOD FOR GENOTYPIC ANALYSIS - A technique for performing spectral calibration simultaneously with electrophoresis of an actual sample to be analyzed, without performing electrophoresis using a special matrix standard which is time-consuming and costly, is provided. The device for genotypic analysis is characterized by obtaining reference fluorescence spectra using a size standard and an allelic ladder, which provide information concerning known DNA fragments used for electrophoresis of an actual sample, and is characterized by performing spectral calibration for a capillary in which the allelic ladder is not used by detecting a shift amount of the fluorescence spectra of the size standard and shifting the reference fluorescence spectra using the shift amount to determine fluorescence spectra. | 2015-11-26 |
20150337361 | Non-Invasive Diagnosis of Graft Rejection in Organ Transplant Patients - The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant. | 2015-11-26 |
20150337362 | METHOD FOR THE SPECIFIC ISOLATION OF NUCLEIC ACIDS OF INTEREST - A method and diagnostic kit for selective isolation of microorganisms of interest and/or nucleic acids of interest including: a) bringing a liquid biological sample into contact with a saponin formulation to destabilize untargeted elements within the liquid biological sample, b) inducing osmotic shock of the untargeted elements to specifically lyse the untargeted elements, c) adding a solution of at least one enzyme capable of lysing free nucleic acids derived from the untargeted elements lysed in solution in the sample, and d) selectively obtaining the microorganisms of interest or the nucleic acids of interest. A precipitant of the unlysed microorganisms of interest may be optionally added in solution. The microorganisms of interest have cell membranes or capsids that do not contain cholesterol. The untargeted elements may include untargeted cells having cell membranes containing cholesterol, and optionally viruses with envelopes containing cholesterol, mycoplasmas containing cholesterol, and cell debris. | 2015-11-26 |
20150337363 | ARRAY FOR DETECTING MICROBES - The present embodiments relate to an array system for detecting and identifying biomolecules and organisms. More specifically, the present embodiments relate to an array system comprising a microarray configured to simultaneously detect a plurality of organisms in a sample at a high confidence level. | 2015-11-26 |
20150337364 | Isothermal Methods and Related Compositions for Preparing Nucleic Acids - According to some aspects of the invention preparative methods and related compositions are provided for nucleic acid sequencing. | 2015-11-26 |
20150337365 | Polymerase Chain Reaction Detection System - The present invention relates to methods and kits for nucleic acid detection in an assay system. | 2015-11-26 |
20150337366 | METHODS FOR CREATING BILAYERS FOR USE WITH NANOPORE SENSORS - The present disclosure provides biochips and methods for making biochips. A biochip can comprise a nanopore in a membrane (e.g., lipid bilayer) adjacent or in proximity to an electrode. Methods are described for forming the membrane and inserting the nanopore into the membrane. The biochips and methods can be used for nucleic acid (e.g., DNA) sequencing. The present disclosure also describes methods for detecting, sorting, and binning molecules (e.g., proteins) using biochips. | 2015-11-26 |
20150337367 | HIGH DENSITY NANOPORE POLYNUCLEOTIDE SEQUENCER - A polynucleotide sequencer comprising an integrated and multiplexed network of patch clamp capacitive integrator-differentiator amplifiers with small feedback capacitors using pseudo-resistors. | 2015-11-26 |
20150337368 | METHODS AND PRIMER SETS FOR HIGH THROUGHPUT PCR SEQUENCING - The invention relates to a method for amplifying a target nucleic acid sequence t | 2015-11-26 |
20150337369 | SINGLE CELL ANALYSIS OF T CELLS USING HIGH-THROUGHPUT MULTIPLEX AMPLIFICATION AND DEEP SEQUENCING - Methods and oligonucleotide reagents for analyzing individual T cells are disclosed. In particular, the present disclosure provides methods for analyzing individual T cells using high-throughput multiplex amplification and deep sequencing of nucleic acids encoding T cell receptors (TCRs) and various other T cell phenotypic markers. The present disclosure further provides methods of reconstituting TCRs from individual T cells for functional studies, ligand discovery, or screening therapeutics. | 2015-11-26 |
20150337370 | INDEPENDENTLY REMOVABLE NUCLEIC ACID SEQUENCING SYSTEM AND METHOD - A technique for sequencing nucleic acids in an automated or semi-automated manner is disclosed. Sample arrays of a multitude of nucleic acid sites are processed in multiple cycles to add nucleotides to the material to be sequenced, detect the nucleotides added to sites, and to de-block the added nucleotides of blocking agents and tags used to identify the last added nucleotide. Multiple parameters of the system are monitored to enable diagnosis and correction of problems as they occur during sequencing of the samples. Quality control routines are run during sequencing to determine quality of samples, and quality of the data collected. | 2015-11-26 |
20150337371 | CREATION OF LIBRARIES OF DROPLETS AND RELATED SPECIES - The present invention is generally related to systems and methods for producing a plurality of droplets. The droplets may contain varying species, e.g., for use as a library. In some cases, the fluidic droplets may be rigidified to form rigidified droplets (e.g., gel droplets). In certain embodiments, the droplets may undergo a phase change (e.g., from rigidified droplets to fluidized droplets), as discussed more herein. In some cases, a species may be added internally to a droplet by exposing the droplet to a fluid comprising a plurality of species. | 2015-11-26 |
20150337372 | METHODS AND APPARATUS FOR SELECTIVELY PROCESSING EGGS ACCORDING TO GENDER AND OTHER CHARACTERISTICS - Methods and apparatuses for processing eggs based upon a characteristic such as gender are provided. Sample material is extracted from each of a plurality of live eggs. The extracted sample material is deposited on a liquid-immobilizing assay template and then assayed to identify eggs having the characteristic. The eggs identified as having the characteristic are processed accordingly. | 2015-11-26 |
20150337373 | Genetic Markers Associated with Degenerative Disc Disease and Uses Thereof - The present invention relates to novel genetic markers associated with degenerative disc disease (DDD), risk of developing DDD and risk of DDD progression, and methods and materials for determining whether a human subject has DDD, is at risk of developing DDD or is at risk of DDD progression. | 2015-11-26 |
20150337374 | ASSESSMENT AND REDUCTION OF RISK OF GRAFT-VERSUS-HOST DISEASE - Methods of assessing and reducing risk of graft versus host disease (GVHD) based on gene expression profiling are described, as well as methods of selecting a suitable transplant donor. Corresponding reagents and kits are also described. | 2015-11-26 |
20150337375 | BIOMARKERS FOR CHRONIC TRAUMATIC ENCEPHALOPATHY - This invention relates to the field of screening for, identifying, diagnosing, and prognosing chronic traumatic encephalopathy (CTE). Specifically, this invention provides various biomarkers for this disease, and methods of using these biomarkers to correctly diagnose, prognose and predict those individuals who would develop CTE after suffering from mild traumatic brain injury. The invention also provides targets for drug development and basic research for CTE and preventative and therapeutic agents for CTE. | 2015-11-26 |
20150337376 | Core Transcriptional Circuitry in Human Cells and Methods of Use Thereof - Disclosed herein are methods for identifying the core regulatory circuitry or cell identity program of a cell or tissue, and related methods of diagnoses, screening, and treatment involving the core regulatory circuitry and/or cell identity programs identified using the methods. | 2015-11-26 |
20150337377 | METHOD OF DIAGNOSIS OF COMPLEMENT-MEDIATED THROMBOTIC MICROANGIOPATHIES - A method for identifying a patient's risk for developing complement-mediated thrombic microangiopathy is described. A sample of genetic material is obtained from a patient. The genetic material is amplified using primers specific for complement-mediated thrombic microangiopathy. After amplification, the genetic sequence of the amplicon is determined. The genetic sequence of the amplicon is compared to a reference sequence, and variations are identified between the sample amplicon and the reference sequence. A variation between the sample amplicon and the reference sequence is indicative of a risk for the patient for developing complement-mediated thrombic microangiopathy. | 2015-11-26 |
20150337378 | METHODS OF DIAGNOSIS AND TREATMENT OF INFLAMMATORY BOWEL DISEASE - The present invention relates to methods of diagnosing and predicting susceptibility to Crohn's Disease and/or IBD, by determining the presence or absence of susceptibility to genetic variants, risk haplotypes and/or protective haplotypes. In an embodiment, the invention provides methods of diagnosing and/or predicting susceptibility to Crohn's Disease in an individual by determining the presence or absence of risk variants at the IL12RB1, IL12RB2, IL17A, IL17RA, IL17RD and/or IL23R locus. | 2015-11-26 |
20150337379 | GENETIC POLYMORPHISMS PREDICTIVE OF NUTRITIONAL REQUIREMENTS FOR CHOLINE IN SUBJECTS - Methods of predicting susceptibility of a subject to develop one or more choline deficiency-associated health effects are provided, comprising determining a genotype of the subject with respect to at least one choline metabolism gene and comparing the genotype of the subject with at least one reference genotype associated with susceptibility to develop the one or more choline deficiency-associated health effects. | 2015-11-26 |
20150337380 | Compositions and Methods for Diagnosing and Assessing Inflammatory Myopathies - The present invention is directed to assay methods for inflammatory myopathies and microarray plates that can be used in carrying out these assays. | 2015-11-26 |
20150337381 | ASSESSMENT OF RISK OF ANEUPLOIDY - The present disclosure relates generally to methods and materials for use in detecting abnormalities of the number of whole chromosomes or chromosome regions (aneuploidy). It has particular utility for assessing the risk of aneuploidy of eggs (i.e., oocytes), fertilised eggs or embryos developed therefrom in the context of in vitro fertilisation. | 2015-11-26 |
20150337382 | FURTHER USE OF PROTEIN KINASE N BETA - The present invention is related to use of protein kinase N beta or a fragment or derivative thereof as a downstream target of the PI 3-kinase pathway, preferably as a downstream drug target of the PI 3-kinase pathway. | 2015-11-26 |
20150337383 | METHOD OF USING FOXO3A POLYMORPHISMS AND HAPLOTYPES TO PREDICT AND PROMOTE HEALTHY AGING AND LONGEVITY - The invention provides methods and compositions relating to identification and use of genetic information from the FOXO3A gene that can be used for determining and increasing an individual's likelihood of longevity and of retaining physical and cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease, including coronary artery (heart) disease, stroke, cancer, chronic pulmonary disease, diabetes, Parkinson's disease and dementia. | 2015-11-26 |
20150337384 | IN VITRO METHOD FOR THE DIAGNOSIS AND SURVEILLANCE OF CANCER - The present invention relates to an in vitro method for the diagnosis and/or the monitoring and/or predicting the progress of a cancer disease, characterized in that in at least one sample the ratio of Tregs-cells to at least one other group of T cells comprising the group of Th17 cells, Th1 cells and/or Th2 cells is determined. | 2015-11-26 |
20150337385 | EXPRESSION PROTEIN-CODING AND NONCODING GENES AS PROGNOSTIC CLASSIFIERS IN EARLY STAGE LUNG CANCER - The invention provides novel biomarkers (four genes BRCA1, HIF1A, DLC1, and XPO1 alone or in combination CODING GENE SELECTION of miR-21) for early stage lung cancer. | 2015-11-26 |
20150337386 | TEST COMPOSITION FOR SCREENING CANCERS - Provided in the present invention are a molecule for biomarking cancers and a test composition for screening cancers and a detection method thereof comprising designing a number of oligonucleotide primers or probes by analyzing specimens for methylated regions of targeted genes PAX1, ZNF582, SOX1 and NKX6-1 in physical examination, and then using the oligonucleotide probes to detect whether methylation exists in the target genes, and further judge the likelihood of the occurrence of cancer. The detection methods for methylation status include methylation-specific PCR, (MSP), quantitative methylation-specific PCR (QMSP), bisulfate sequencing (BS), microarrays, mass spectrometer, denaturing high-performance liquid chromatography (DHPLC), pyrosequencing, and enzyme-linked immunosorbent assay (ELISA). | 2015-11-26 |
20150337387 | N-MYRISTOYLTRANSFERASE 2 OVEREXPRESSION IN PERIPHERAL BLOOD AND PERIPHERAL BLOOD MONONUCLEAR CELLS IS A MARKER FOR COLORECTAL CANCER - Described herein is the Identification of the NMT isozyme overexpressed in PB-MCs of colorectal cancer patients and the cell types overexpressing NMT2 in the PBMCs of CRC patients. | 2015-11-26 |
20150337388 | METHODS AND COMPOSITIONS FOR IDENTIFYING GLOBAL MICROSATELLITE INSTABILITY AND FOR CHARACTERIZING INFORMATIVE MICROSATELLITE LOCI - The disclosure provides methods and systems for assessing microsatellites, for identifying informative microsatellite loci, and for using microsatellite data. Microsatellite information has numerous uses including, for example, to characterize disease risk, to predict responsiveness to therapy, and to non-invasively diagnose subjects. | 2015-11-26 |
20150337389 | Use Of Genetic Modifications In Human Gene CHK1 Which Codes For Checkpoint Kinase 1 - The invention relates to an in vitro method for predicting disease risks, progression of diseases, drug risks, success of treatment and for finding drug targets by looking for one or more genetic modifications in the promoter region of the CHK1 (CHEK1) gene on human chromosome 11q23, the genetic modifications being a substitution thymine for guanine in position −1143 in the promoter of CHK1, of thymine for cytosine in position −1400, a substitution of cytosine for thymine in position −1453 or an insertion of one cytosine in position −1454 and the genetic modifications being detected individually or in any combinations by way of known methods. | 2015-11-26 |
20150337390 | KITS FOR ANTIANDROGEN THERAPY MONITORING - The present invention provides methods of evaluating the effectiveness of an antiandrogen therapy in a human by comparing the pre- and post antiandrogen treatment levels of an androgen modulated diagnostic marker and a prostate-specific, androgen independent, diagnostic marker in the human. Methods utilizing these markers are also provided that are useful for identifying antiandrogen compounds capable of killing prostate cancer cells, and identifying a human suspected of responding more, or less, favorably to treatment with an antiandrogen compound and monitoring the treatment thereof. Kits and compositions related to these methods are also provided. | 2015-11-26 |
20150337391 | METHOD AND PROBE SET FOR DETECTING CANCER - Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described. | 2015-11-26 |
20150337392 | MARKERS FOR ENDOMETRIAL CANCER - The invention relates to the surprising finding that biomarkers corresponding to ACAA1, AP1M2, CGN, DDR1, EPS8L2, FASTKD1, GMIP, IKBKE, P2RX4, P4HB, PHKG2, PPFIBP2, PPP1R16A, RASSF7, RNF183, SIRT6, TJP3, EFEMP2, SOCS2, and DCN are differentially expressed in control samples as compared to samples from patients having endometrial cancer and are therefore useful for detecting endometrial cancer. In particular these biomarkers having excellent sensitivity, specificity, and/or the ability to separate affected from non affected individuals. Furthermore, the inventors found that the differential expression of these biomarkers in primary endometrial cancer tumor tissue is correlated to their expression level in uterine fluid samples as compared to control values. Thus these biomarkers are robust in that they are found to be differentially expressed in several different types of samples from affected and individuals. | 2015-11-26 |
20150337393 | miRNA FINGERPRINT IN THE DIAGNOSIS OF PROSTATE CANCER - MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing prostate cancer based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls | 2015-11-26 |
20150337394 | SOYBEAN EVENT pDAB9582.816.15.1 DETECTION METHOD - Soybean Event pDAB9582.816.15.1 comprises gene expression cassettes which contain genes encoding Cry1F, Cry1Ac (synpro), and PAT, affording insect resistance and herbicide tolerance to soybean crops containing the event, and enabling methods for crop protection and protection of stored products. The disclosure provides polynucleotiderelated event detection methods. The present disclosure relates to a method for detecting a new insect resistant and herbicide tolerant transgenic soybean transformation event, designated Soybean Event pDAB9582.816.15,1. The DNA of soybean plants containing this event includes the junction/flanking sequences described herein that characterize the location of the inserted DNA within the soybean genome. SEQ ID NO: 1 and SEQ ID N0:2 are diagnostic for Soybean Event pDAB9582.816.15.1. | 2015-11-26 |
20150337395 | Molecular markers and methods for identifying date palm genotypes - The present invention concerns two sets of mini- and micro-satellite molecular markers, and the use thereof to study the genetic diversity and/or identify the genotypes of date palms. The invention also concerns method for identifying date palm cultivars using these sets of molecular markers, and kits for implementing these methods. | 2015-11-26 |
20150337396 | METHOD AND COMPOSITIONS FOR DETECTING FUNGI AND MYCOTOXINS - The invention relates to a method of identifying a specific fungal species in patient tissue or body fluid. The method comprises the steps of extracting and recovering DNA of the fungal species from the patient tissue or body fluid, amplifying the DNA, hybridizing a probe to the DNA to specifically identify the fungal species, and specifically identifying the fungal species. The invention also relates to a method of identifying a mycotoxin in patient tissue or body fluid. The method comprises the steps of extracting and recovering the mycotoxin from the patient tissue or body fluid, contacting the mycotoxin with an antibody directed against the mycotoxin, and identifying the myocotoxin. Both of these methods can be used to determine if a patient is at risk for or has developed a disease state related to a fungal infection, and to develop an effective treatment regimen for the patient. | 2015-11-26 |
20150337397 | Methods and Compositions for Selecting Soybean Plants Resistant to Brown Stem Rot - The present invention is in the field of plant breeding and disease resistance. More specifically, the invention includes methods and compositions for breeding soybean plants containing quantitative trait loci that are associated with resistance to Brown Stem Rot (BSR), a fungal disease associated with | 2015-11-26 |
20150337398 | OLIGONUCLEOTIDE PROBES, KIT CONTAINING THE SAME AND METHOD FOR PATHOTYPING OF H5 AVIAN INFLUENZA VIRUSES - The present invention provides a group of specific probes directed to cleavage site of hemagglutinin precursor protein of avian influenza virus subtypes H5, and provides a method for rapid pathotyping of H5 avian influenza virus. The present invention further provides a kit containing the probes and the kit is easy-to-use, low-cost, high sensitivity, enabled the molecular pathotyping of H5 viruses by a simpler and faster means that conventional methods. | 2015-11-26 |
20150337399 | HIV-1 GENOTYPING AND CORECEPTOR TROPISM ASSAY - A method for detecting low frequency occurrence of one or more HIV sequence variants associated with drug resistance and HIV tropism includes generating a plurality of cDNA species from a plurality of RNA molecules in an HIV sample population, amplifying a plurality of first amplicons and second amplicons from the cDNA species, wherein the first amplicons are amplified using first pairs of primers that amplify a HIV genomic region of the cDNA species encoding the Gag proteins p2, p7, p1 and p6, and the protease, reverse transcriptase, and integrase enzymes and the second amplicons are amplified using second pairs of primers that amplify a HIV genomic encoding region of the cDNA species encoding the env-C2V3 region; determining the nucleic acid sequence compositions of the amplified first amplicons second amplicons; identifying variants in the determined sequence by comparing the determined nucleic sequence to a guide sequence; and correlating the determined variants with variants of HIV drug resistance and HIV tropism. | 2015-11-26 |
20150337400 | SYSTEM AND METHOD FOR CONTROLLING THERMAL CYCLER MODULES - Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples. | 2015-11-26 |
20150337401 | PLANT-BIOMASS HYDROLYSIS METHOD - A method for hydrolyzing a plant biomass, including hydrothermal treatment in which an equivalent concentration of an acid equal to the total of 30 to 1,000% of the equivalent concentration of cations and equivalent concentration of hydroxide ions in a plant-biomass hydrolysis reaction solution is added to the reaction solution; and a method for producing glucose using the above method for hydrolyzing a plant biomass. The hydrothermal treatment is desirably conducted using a solid catalyst including a carbon material and an inorganic acid. The method can eliminate reaction-inhibiting factors due to cations existing in the reaction system to thereby attain a high glucose yield. | 2015-11-26 |
20150337402 | PLANT-BIOMASS HYDROLYSIS METHOD - A method for hydrolyzing a plant biomass, which includes a first process of heating a mixture containing a plant biomass, a solid catalyst, acid and water, and a second process for heating the mixture containing a solid containing a plant biomass and a catalyst separated from the reaction solution after the first process, acid and water, wherein the highest heating temperature in the second process is higher than that in the first process; and a method for producing glucose and xylose using the above-mentioned hydrolyzing method. In the method, both of glucose and xylose can be obtained efficiently from an actual biomass. | 2015-11-26 |
20150337403 | PLANT-BIOMASS HYDROLYSIS METHOD - A method for hydrolyzing a plant biomass, which includes hydrothermal treatment in the presence of an equivalent concentration of an acid equal to 30 to 1,000% of the equivalent concentration of cations in a plant-biomass hydrolysis reaction solution; and a method for producing glucose using the above method for hydrolyzing a plant biomass. The hydrothermal treatment is preferably conducted by using a solid catalyst comprising a carbon material and using inorganic acid as acid. The method eliminates reaction-inhibiting factors to thereby obtain a high glucose yield. | 2015-11-26 |
20150337404 | METHOD AND DEVICE FOR PREDICTING, CONTROLLING AND/OR REGULATING STEELWORKS PROCESSES - The present invention relates to a method for predicting, controlling and/or regulating steelworks processes, comprising the steps of monitoring at least two input variables related to a target variable, determining the relationship between the at least two input variables and at least one target variable by means of regression analysis or classification methods, and using the determined target variable for predicting, controlling and/or regulating the steelworks process. | 2015-11-26 |
20150337405 | ULTRASONIC IMPACT TREATMENT FOR USEFUL LIFE IMPROVEMENT OF DOWNHOLE TOOLS - The useful life of a downhole tool is improved through application of an ultrasonic impact treatment. In an example method, operational parameters of an ultrasonic impact treatment device are selected based upon the one or more physical characteristics of the downhole tool. The ultrasonic impact treatment device is configured to correspond to the selected operational parameters. A residual compressive stress layer is then induced along a surface of the downhole tool using the configured ultrasonic impact treatment device, thereby improving the useful life of the downhole tool. | 2015-11-26 |
20150337406 | MANUFACTURING A HARDENED FORMED PART - A hardened formed part is manufactured with the steps: producing a blank from a hardenable strip material; heating of the blank to an austenitisation temperature; forming and hardening of the blank to a hardened formed part; cleaning the hardened formed part; coating the hardened formed part with a metallic coating in an dipping bath with an electrolyte solution, wherein during the coating process, at least one auxiliary element is used in the dipping bath, such, that the deposition of the coating is partially influenced. A plant is used for manufacturing a hardened formed part. | 2015-11-26 |
20150337407 | SUPPORT DEVICE FOR RADIANT TUBES - A radiant tubes support device, which can be used in furnaces for the thermal treatment, for continuous lines for galvanising and annealing strips or panels made of metal sheet or other products made of steel or other metals, including a furnace side wall support, constrained to a wall of the furnace, a radiant tube support provided with a tubular element and anti-sticking means between the tubular element and the furnace side wall support for supporting the radiant tube and allowing the lateral oscillation thereof, avoiding the sticking on the furnace side wall support. | 2015-11-26 |
20150337408 | HIGH STRENGTH MULTI-PHASE STEEL, AND METHOD FOR PRODUCING A STRIP FROM SAID STEEL - A high-strength multiphase steel with minimum tensile strengths of 580 MPa, preferably having a dual-phase structure for a cold-rolled or hot-rolled steel strip with improved forming properties, particularly for lightweight vehicle construction contains the elements (contents in mass-%): C 0.075 to ≦0.105; Si 0.600 to ≦0.800; Mn 1.000 to ≦2.250; Cr 0.280 to ≦0.480; Al 0.010 to ≦0.060; P≦0.020; N≦0.0100; S≦0.0150, remainder iron, including typical steel-accompanying elements not mentioned above, which are impurities introduced by smelting, with the condition that the Mn content is preferably ≦1.500% for strip thicknesses up to 1 mm, the Mn content is preferably ≦1.750% for strip thicknesses of 1 to 2 mm, and the Mn content is preferably ≧1.500% for strip thicknesses ≧2 mm | 2015-11-26 |
20150337409 | METHOD OF TREATING RECYCLABLE RAW MATERIALS - A method of treating recyclable raw materials containing valuable metals is provided, the method including the steps of feeding recyclable raw materials (W) containing valuable metals into a rotary kiln furnace ( | 2015-11-26 |
20150337410 | HEAP LEACHING - A heap of a material to be leached to recover a valuable metal from the material includes an electromagnetic heating system to generate heat in situ in the heap. | 2015-11-26 |
20150337411 | SOLID-LIQUID-SEPARATION PROCESSING METHOD, AND HYDROMETALLURGICAL METHOD FOR NICKEL OXIDE ORE - A solid-liquid-separation processing method wherein solids in a slurry are separated and removed by applying multistage washing to the slurry, wherein the case where the number of connected thickening-apparatus stages is smaller, the clarity of obtained supernatant liquid is improved. In the solid-liquid-separation processing method wherein thickening apparatuses each equipped with agitation and sedimentation tanks having an overflow unit in a peripheral portion to discharge supernatant liquid and cylindrical feed well vertically arranged at a central portion are provided in multiple stages; multistage washing is applied to a slurry to separate solids in the slurry therefrom and obtain a solution from which the solids are removed, when a flocculant configured to flocculate the solids in the slurry is added, a flocculant predetermined proportion is added to a feed well in a first-stage thickening apparatus, and remainder of the flocculant is added to an overflow unit in a second-stage thickening apparatus. | 2015-11-26 |
20150337412 | OXIDATION OF AMERICIUM IN ACIDIC SOLUTION - A process is for oxidizing americium(III) to americium(VI) includes providing a aqueous acidic composition comprising americium(III) and a mineral acid and exposing the composition to ozone and silver ion under conditions suitable for oxidation of the americium(III) to americium(VI). Nitric, acid is a suitable mineral acid for the process. Extraction of the americium from the silver is possible using organic phosphonate extractant. | 2015-11-26 |
20150337413 | HIGH HEAT-DISSIPATING HIGH STRENGTH ALUMINUM ALLOY - The present invention relates to a high heat-dissipating, high strength aluminum alloy, more particularly to an aluminum alloy containing, as essential components, manganese (Mn), silicon (Si) and magnesium (Mg) at a predetermined content ratio and further containing one or more metal selected from a group consisting of copper (Cu), iron (Fe), zirconium (Zr), chromium (Cr) and titanium (Ti) at a predetermined content ratio, with the remainder being aluminum (Al) and inevitable impurities. | 2015-11-26 |
20150337414 | COMPOSITION FOR REACTIVE MATERIAL - A composition includes an alloy that has, by weight, 25-65% zirconium, 25-65% tungsten, and 6-25% of a combined amount of nickel in at least one of iron and cobalt. The alloy may be formed into a geometric body that has a density of 7.8 grams per cubic centimeter to 11.4 grams per cubic centimeter. | 2015-11-26 |
20150337415 | STEEL SHEET FOR HOT PRESS-FORMING, HOT PRESS-FORMED PART, AND METHOD OF PRODUCING HOT PRESS-FORMED PART - A steel sheet for hot press-forming includes a zinc coating layer and a Si-containing compound layer in this order on a base steel sheet, wherein the Si-containing compound layer contains a silicone resin having an organic functional group of a carbon number of 4 or more. | 2015-11-26 |
20150337416 | HIGH-FORMABILITY AND SUPER-STRENGTH COLD-ROLLED STEEL SHEET AND MANUFACTURING METHOD THEREOF - A high-formability and super-strength cold-rolled steel sheet and a manufacturing method thereof. The weight percentage of its components is: C 0.15-0.25%, Si 1.00-2.00%, Mn 1.50-3.00%, P≦0.015%, S≦0.012%, Al 0.03-0.06%, N≦0.008%, and the rest are Fe and inevitable impurities. The manufacturing method comprises the following steps: 1) smelting and casting; 2) heating to 117˜1230° C. and performing thermal insulation; 3) performing hot rolling, the finish rolling temperature being 880+30° C., and coiling at 550˜650° C.; and 4) performing acid washing, cold rolling, and annealing, the cold rolling reduction being 40-60%, annealing at 860-920° C., and performing slow cooling to 690-750° C. with the cooling rate of 3˜10° C./s; performing rapid cooling at 240˜320° C., with the cooling speed ≧50° C./s, then heating to 360˜460° C., and performing thermal insulation for 100˜500 s to cool to the room temperature at last. Finally, a high-formability, low-rebound property and super-strength cold-rolled steel sheet with the yield strength of 600˜900 MPa, the tensile strength of 980˜1150 MPa, the elongation of 17˜25% is obtained. | 2015-11-26 |
20150337417 | MICROSTRUCTURE OF HIGH-ALLOY STEEL AND A HEAT TREATMENT METHOD OF PRODUCING THE SAME - A method of producing a microstructure of a high-alloy steel includes heating the metal stock to a temperature between 1270° C. and 1280° C., at a rate between 40° C./s and 45° C./s, followed by compression applied to the metal stock in a thixotropic process, after which the stock is cooled to ambient temperature. A microstructure is also shown, which includes undissolved metal carbides in the form of globular particles of austenite microstructure and of martensite microstructure. | 2015-11-26 |
20150337418 | FERRITIC STAINLESS STEEL - The invention relates to a ferritic stainless steel having enhanced high temperature strength and good resistance to high cycle fatigue, creep and oxidation for use in high temperature service, for components such as automotive exhaust manifolds. The steel contains in weight % less than 0.03% carbon, 0.05-2% silicon, 0.5-2% manganese, 17-20% chromium, 0.5-2% molybdenum, less than 0.2% titanium, 0.3-1% niobium, 1-2% copper, less than 0.03% nitrogen, 0.001-0.005% boron, the rest of the chemical composition being iron and inevitable impurities occurring in stainless steels. | 2015-11-26 |
20150337419 | Austenitic Stainless Steel Alloy - An austenitic stainless steel alloy is provided that includes 0.7-1.2 wt % of N, 10-25 wt % of Ni, 26-34 wt % of Cr, 0.1-1.0 wt % of Nb, 0.1-1.0 wt % of V, and a balance of Fe and incidental impurities. | 2015-11-26 |
20150337420 | Superelastic Alloy Structural Geometry for Ultrahigh Mechanical Damping - A mechanical structure is provided with a crystalline super alloy that is characterized by an average grain size and that exhibits a martensitic phase transformation resulting from a mechanical stress input greater than a characteristic first critical stress. A configuration of the superelastic alloy is provided with a geometric structural feature of the alloy that has an extent that is no greater than about 200 micrometers and that is no larger than the average grain size of the alloy. This geometric feature undergoes the martensitic transformation without intergranular fracture of the geometric feature. | 2015-11-26 |
20150337421 | LEAN AUSTENITIC STAINLESS STEEL - An austenitic stainless steel composition including relatively low Ni and Mo levels, and exhibiting corrosion resistance, resistance to elevated temperature deformation, and formability properties comparable to certain alloys including higher Ni and Mo levels. Embodiments of the austenitic stainless steel include, in weight percentages, up to 0.20 C, 2.0-9.0 Mn, up to 2.0 Si, 15.0-23.0 Cr, 1.0-9.5 Ni, up to 3.0 Mo, up to 3.0 Cu, 0.05-0.35 N, (7.5(C))≦(Nb+Ti+V+Ta+Zr)≦1.5, Fe, and incidental impurities. | 2015-11-26 |
20150337422 | LEAN AUSTENITIC STAINLESS STEEL CONTAINING STABILIZING ELEMENTS - An austenitic stainless steel composition including relatively low nickel and molybdenum levels, and exhibiting corrosion resistance, resistance to elevated temperature deformation, and formability properties comparable to certain alloys including higher nickel and molybdenum levels. Embodiments of the austenitic stainless steel include, in weight %, up to 0.20 C, 2.0 to 9.0 Mn, up to 2.0 Si, 16.0 to 23.0 Cr, 1.0 to 7.0 Ni, up to 3.0 Mo, up to 3.0 Cu, 0.05 to 0.35 N, up to 4.0 W, (7.5(C))≦(Nb+Ti+V+Ta+Zr)≦1.5, up to 0.01 B, up to 1.0 Co, iron and impurities. Additionally, embodiments of the steel may include 0.5≦(Mo+W/2)≦5.0 and/or 1.0≦(Ni+Co)≦8.0. | 2015-11-26 |
20150337423 | HYDRIDE-COATED MICROPARTICLES AND METHODS FOR MAKING THE SAME - A metal microparticle coated with metal hydride nanoparticles is disclosed. Some variations provide a material comprising a plurality of microparticles (1 micron to 1 millimeter) containing a metal or metal alloy and coated with a plurality of nanoparticles (less than 1 micron) containing a metal hydride or metal alloy hydride. The invention eliminates non-uniform distribution of sintering aids by attaching them directly to the surface of the microparticles. No method is previously known to exist which can assemble nanoparticle metal hydrides onto the surface of a metal microparticle. Some variations provide a solid article comprising a material with a metal or metal alloy microparticles coated with metal hydride or metal alloy hydride nanoparticles, wherein the nanoparticles form continuous or periodic inclusions at or near grain boundaries within the microparticles. | 2015-11-26 |