48th week of 2021 patent applcation highlights part 13 |
Patent application number | Title | Published |
20210369867 | LIPID NANOPARTICLE FORMULATIONS COMPRISING LIPIDATED CATIONIC PEPTIDE COMPOUNDS FOR NUCLEIC ACID DELIVERY - The present disclosure relates to lipid mixtures comprising lipidated cationic peptide compounds, such as tertiary amino lipidated and/or PEGylated cationic peptide compounds or lipitoids, for nucleic acid delivery. More specifically, the present disclosure relates to lipid nanoparticle formulations comprising lipidated cationic peptide compounds and other lipid components including structural lipid, phospholipid and shielding lipids. The present disclosure also relates to methods of preparing and using the lipid mixtures. | 2021-12-02 |
20210369868 | Optimized Liver-Specific Expression Systems for FVIII and FIX - The present invention relates to nucleic acid expression cassettes and vectors containing liver-specific regulatory elements and codon-optimized factor IX or factor VIII transgenes, methods employing these expression cassettes and vectors and uses thereof. The present invention is particularly useful for applications using liver-directed gene therapy, in particular for the treatment of hemophilia A and B. | 2021-12-02 |
20210369869 | NUCLEIC ACID MOLECULES CONTAINING SPACERS AND METHODS OF USE THEREOF - The present invention relates to nucleic acid molecules containing spacers and methods of using the same. | 2021-12-02 |
20210369870 | COMPOSITIONS AND METHODS FOR TREATING WILSON'S DISEASE - Provided herein are nucleic acid molecules and vectors comprising variant copper transporting ATPase 2 (ATP7B) nucleic acid sequences. Such sequences have been optimized for expression in mammalian cells, liver cells, and/or from an adeno associated viral vector (AAV), including truncated and/or codon optimized variants. Also provided are viral vectors comprising such ATP7B variant nucleic acid sequences, and methods of use thereof for treating disorders associated with an ATP7B deficiency, such as Wilsons disease. | 2021-12-02 |
20210369871 | ADENO-ASSOCIATED VIRUS FOR THERAPEUTIC DELIVERY TO CENTRAL NERVOUS SYSTEM - A method to prevent, inhibit or treat one or more symptoms associated with disease of the central nervous system by intranasally, intrathecally, intracerebrcvascularly or intravenously administering a rAAV encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease, in an amount effective, e.g., to provide for cross-correction. | 2021-12-02 |
20210369872 | HTT REPRESSORS AND USES THEREOF - Disclosed herein are Htt repressors and methods and compositions for use of these Htt repressors. | 2021-12-02 |
20210369873 | COMPOSITIONS AND METHODS FOR DETECTION OF TRAUMATIC BRAIN INJURY - The present disclosure relates generally to compositions and methods for determining whether a patient suffers from a traumatic brain injury (TBI) by detecting the presence of an amyloid beta protein in an eye of the patient. Also provided are compositions and methods for preparing a patient for diagnosis and treatment of traumatic brain injury (TB). | 2021-12-02 |
20210369874 | COMPOSITION FOR DETECTING BIOFILMS ON VIABLE TISSUES - A staining composition for use in making biofilm detectable on viable tissue wherein the composition preferentially stains the biofilm and comprises a staining agent in a quantity effective to stain said biofilm and render it detectable. | 2021-12-02 |
20210369875 | ALGINIC ACID-BASED INJECTABLE HYDROGEL SYSTEM - The present invention provides an alginic acid-based injectable hydrogel system for labeling an accurate position of a disease lesion and effectively delivering a drug to a target region. The formulation of the present invention can make it easy to locally inject a contrast agent and a drug into a target region while controlling the release rate of the contrast agent or the drug, with the formation of the hydrogel in the injected region. Through the advantages, the labeled position can be accurately determined from images, thereby enhancing the precision of surgical operation, with a minimal incision formed therefor. In addition, when used, the alginic acid-based injectable hydrogel system allows the effective local delivery of a drug to a target region while increasing the long-acting effect of the drug. | 2021-12-02 |
20210369876 | CHEMILUMINESCENT AND FLUORESCENT NANOPARTICLE FOR OPTICAL IMAGING OF CANCER - The present invention provides compositions and methods for detecting tumor tissues in a subject. Embodiments of the present invention provide biocompatible chitosan nanoparticles suitable for dual modality optical imaging. Embodiments of the present invention provide methods for fabricating chitosan nanoparticles. Embodiments of the present invention provide methods for detecting tumor tissues in a subject using compositions provided by the present invention. | 2021-12-02 |
20210369877 | MARKING PRECURSOR WITH SQUARIC ACID COUPLING - The invention relates to a marking precursor incorporating a chelator or fluorination group for radiolabelling with 44Sc, 47Sc, 55Co, 62Cu, 64Cu, 67Cu, 66Ga, 67Ga, 68Ga, 89Zr, 86Y, 90Y, 90Nb, 99mTc, 111ln, 135Sm, 140Pr, 159Gd, 149Tb, 160Tb, 161Tb, 165Er, 166Dy, 166Ho, 175Yb, 177Lu, 186Re, 188Re, 213Bi and 225Ac or with 18F, 131I or 211At, and one or two biological targeting vectors which are coupled to the chelator or fluorinating group via one or more squaric acid groups. | 2021-12-02 |
20210369878 | KITS AND METHODS FOR PREPARING RADIOPHARMACEUTICALS - Disclosed herein are kits and methods for preparing radiopharmaceuticals. The kits and methods of the present disclosure can prepare the radiopharmaceuticals without using a heater and computer monitoring equipment. The kit includes a frozen crystal reaction vial, a reagent vial and a labeling holder, wherein the labeling holder contains a heating bag that can heat up to a high temperature of at least 95° C. by adding an aqueous solution. | 2021-12-02 |
20210369879 | DECONTAMINATION OF BODY SURFACES AND ARTICLES WITH HARMLESS RADIATION AND RELATED METHODS - A system and method that include using biophotonic and/or phononic systems for deactivating viruses, bacteria, and other pathogens that may be present on people, their clothing, or other surfaces. Biophotonic refers to the use of photons in specific wavelengths of the FAR—Ultraviolet C radiation and/or FAR—Infrared C radiation to affect the interior structure and chemistry of bacteria and viruses to degrade them and render them harmless. The infrared radiation may also provide a phononic effect that degrades the physical conditions of the cell or virus sufficiently to disrupt the cellular machinery, deactivating the virus. Furthermore, a higher temperature Inside the UVIR system makes negligible the rate of propagation of the Virus. The system of the present invention is operable to use electromagnetic radiation to disinfect the exterior surfaces of living mammal animals without harming the animal's tissue, but still effective to degrade microbe and sanitize the exterior surfaces. | 2021-12-02 |
20210369880 | Assembly for dispensing sanitiser fluid - An assembly | 2021-12-02 |
20210369881 | LOW-FLOW HAND SANITATION UNIT - The disclosed technology includes a system for sanitizing a user's hands or other objects using atomized water. The system can include a heating element for heating air, a blower for directing the heated air toward a user's hands or other objects, and one or more reservoirs for holding fluids, such as water and a sanitizing agent. The system can include an atomizing device for atomizing at least some of the fluid. The system can include a controller for controlling the various components of the system. | 2021-12-02 |
20210369882 | SYSTEMS AND METHODS FOR STERILIZING WASTE - Disclosed herein is a receptacle configured to receive and contain waste, such as medical waste, during sterilization, wherein the receptacle is water permeable and heat resistant at a temperature of up to about 320° F. Also disclosed are systems and methods for sterilizing waste, such as with an autoclave, including the use of the receptacle. | 2021-12-02 |
20210369883 | SELF-CLEANING DEVICE - This document describes self-cleaning devices. In one aspect, a self-cleaning device includes a fabric having a surface covered with a photocatalyst, one or more light sources embedded in the fabric, and a triggering mechanism that activates a cleaning cycle by activating the one or more light sources. The triggering mechanism can include a pressure sensor. The triggering mechanism can be configured to activate the cleaning cycle in response to detecting a decrease in pressure being applied to the pressure sensor. | 2021-12-02 |
20210369884 | UV-C STERILIZER ATTACHABLE TO INPUT PAD OF AUTOMATED MACHINE - Provided is a sterilizer simply attached to the edges of an input pad of an existing automated machine, wherein a moving UV bar ( | 2021-12-02 |
20210369885 | UV-C STERILIZER ATTACHABLE TO TOUCH SCREEN OF AUTOMATED MACHINE - Provided is a sterilizer which is simply attached to the bezel of a touch screen of the existing automated machine (an ATM, a kiosk, or a vending machine, etc.), and sterilizes the surface of the touch screen by vertically moving the moving UV bar ( | 2021-12-02 |
20210369886 | ASSEMBLY FOR THE SANITATION OF THE TERMINALS OF WASTEWATER DISCHARGING PIPES - A sanitation assembly for sanitation of terminals of wastewater discharging pipes includes a sanitation chamber inside which, while in use, there is located a terminal to be sanitized. A fixed UV emission means is located inside the sanitation chamber near a bottom portion thereof and arranged to emit a UV radiation upwards, the fixed UV emission means including a first plurality of LEDs arranged along a first circumference and a second plurality of LEDs arranged along a second circumference inside said first circumference, the first and the second plurality of LEDs being arranged to emit upward a UV radiation having a wavelength ranging from 200 and 300 nm. A movable UV emission means is housed inside the sanitation chamber and includes a third plurality of LEDs designed to emit a radiation ranging from 200 and 300 nm and arranged along a circumference on a vertically moving ring-shaped structure which, while in use, is arranged to surround the terminal to be subject to sanitation. The LEDs of the third plurality of LEDs are designed to emit, in a converging manner, a UV radiation having the wavelength ranging from 200 to 300 nm. | 2021-12-02 |
20210369887 | SANITIZATION DEVICES - In some examples, a sanitization device includes an elongated member, a plurality of sanitizing sources located on a surface of the elongated member, and an attachment mechanism coupled to the elongated member, where the attachment mechanism is to couple the elongated member to an electronic device including a display. | 2021-12-02 |
20210369888 | DISINFECTING AND ILLUMINATING LIGHTING ASSEMBLIES - A lighting assembly includes a lightbulb, sleeve, motor assembly, a control circuit, power source, first state, and second state. The control circuit is communicatively coupled to the power source, the lightbulb, and the motor assembly. The lightbulb emits ultra violet (“UV”) radiation. The sleeve converts UV radiation to visible light, is circumferentially positioned about the lightbulb, and is rotatably coupled to the lightbulb via the motor assembly. The motor assembly is mechanically coupled to the sleeve, and selectively rotates the sleeve about the lightbulb and thereby positions the lighting assembly in the first state or the second state. The sleeve includes a slit that emits the UV radiation from the lightbulb. In the first state, the lighting assembly emits UV radiation towards a surface. In the second state, the lighting assembly emits visible light towards the surface. | 2021-12-02 |
20210369889 | PLAYING CARD CLEANER - A card cleaning apparatus comprises an input bin, an output bin, and a cleaning module disposed between the input and output bins. The input bin receives a stack of playing cards. The cleaning module includes a housing, a UV-C light source, and a card guide. The UV-C light source and the card guide are contained within the housing. A plurality of rollers transport individual cards from the stack along a card transport path. The card transport path extends from the input bin to the output bin via the card guide of the cleaning module. The UV-C light source emits UV-C light onto each card while it is in the card guide to clean the cards. | 2021-12-02 |
20210369890 | REDUCING MICROBIAL GROWTH ON PACKAGED TERMINAL AIR CONDITIONERS - An antimicrobial lighting system is used to reduce microbial growth on surfaces in or on air conditioning and/or heating equipment. In some examples, antimicrobial light within one or more antimicrobial wavelength ranges is applied to inactivate one or more microorganisms on target surface(s) within or on a packaged terminal air conditioner (PTAC). The antimicrobial light may include light within a first antimicrobial wavelength range and/or light within a second antimicrobial wavelength range. The antimicrobial lighting system may include an array of individually controllable antimicrobial light segments. An array controller may individually control activation of the one or more antimicrobial light segments based on the status information or commands received from a PTAC controller or from an external computing device. | 2021-12-02 |
20210369891 | MICROBIAL DECONTAMINATION OF COMMON TOUCH ARTICLES - An antimicrobial lighting system includes an antimicrobial lighting array that emits antimicrobial light within one or more antimicrobial wavelength ranges to inactivate one or more microorganisms on common touch surfaces. The common touch surfaces may include, for example, restaurant menus, airline safety instructions, pamphlets, instruction cards, or other common touch objects having a generally flat form factor, or that can be reduced to a flat form factor. Application of the antimicrobial light to the common touch surfaces may improve hygiene of such common touch surfaces and may help maintain microbial growth below acceptable levels. | 2021-12-02 |
20210369892 | PORTABLE UV-C PATHOGEN INACTIVATION APPARATUS FOR HUMAN BREATHING AIR - System and method for pathogen inactivation with UV-C light (employed by itself or in addition to filtering out particulates rom the flow of air reaching the user) by delivering, into a lightguide portion of the air inactivation chamber of the system, a dose of ultraviolet radiation sufficient for at least one log reduction level of the pathogen while, at the same time, multiply reflecting the light inside the chamber to increase the irradiance of inactivating light several fold (up to 5×, or even up to 8.6×) as compared to that delivered to the chamber. | 2021-12-02 |
20210369893 | SANITATION ASSEMBLY - A sanitation assembly for sanitizing and/or sterilizing a space. | 2021-12-02 |
20210369894 | STERILIZATION MODULE AND STERILIZATION DEVICE INCLUDING THEREOF - A sterilization apparatus includes a support member and multiple germicidal light sources. The multiple germicidal light sources are mounted on the support member and emit germicidal light which is light having a wavelength capable of inactivating microorganisms. In addition, respective light exit surfaces of the multiple germicidal light sources face in different directions from one another. Further, an irradiance of the germicidal light delivered to a sterilization target is greater than a minimum irradiance required for sterilization. | 2021-12-02 |
20210369895 | UV SANITIZING CABINET - A UV sanitizing cabinet includes outer walls and a control panel located thereon. An inner enclosure is defined by inner walls and a pivotally mounted door that may be selectively moved between an open orientation and a closed orientation. An upper rack and a lower rack are selectively positioned within the enclosure. At least one UV lamp is positioned below the lower rack within the enclosure and at least one UV lamp is positioned above the upper rack within the enclosure. A middle shelf is selectively positioned within the enclosure. Tracks are secured along the inner walls for supporting the upper and lower racks, as well as the middle shelf, in a manner allowing for selective removal and insertion thereof such that the cabinet can support various electronic devices with minimal contact, including, those with a hinge in an open 180 degree orientation. | 2021-12-02 |
20210369896 | Cold Plasma Sanitization Robot - A cold plasma system to disinfect PPE while disinfecting a floor surface, comprising a positive air ion collector on a top portion and a negative air ion collector on a lower portion. | 2021-12-02 |
20210369897 | FOOTWEAR SANITIZATION SYSTEM - A footwear sanitization system or floormat which may have one or more zones to. The zones may include a disinfecting zone, a drying zone, a scraping zone that are used to perform different procedures on the footwear for the purposes of cleaning or sanitizing the footwear when the footwear is in or on the zone. | 2021-12-02 |
20210369898 | DISINFECTANT POUCH WITH FLUID CONTROL - A disinfectant device including a pouch, the pouch including a first layer of material coupled to a second layer of material and defining a compartment therebetween. At least one dry reactant is retained within the compartment, the at least one dry reactant producing chlorine dioxide gas when exposed to water. A wick is at least partially disposed within the compartment. At least one from the group consisting of the first layer of material and the second layer of material define an array of ports along a periphery of the pouch and an array of fluid conduits, the array of fluid conduits being proximal to the array of ports, offset from the array of ports, in fluid communication with the wick, the compartment, and the array of ports. | 2021-12-02 |
20210369899 | Sterilization Method and Apparatus - Disclosed is a method of sterilizing an article by sequentially exposing the article under vacuum first to a gaseous conditioning agent for forming radicals and then to a sterilant. The preferred conditioning agent is hydrogen peroxide and the preferred sterilant is ozone. The chamber is initially evacuated to a first vacuum pressure and then sealed for the remainder of the sterilization process and during all sterilant injection cycles, without removal of any component of the sterilization atmosphere, which means without any measures to reduce the water vapor content. Keeping the chamber sealed and maintaining the conditioning agent and the radicals generated thereby in the chamber for the sterilization with sterilant results in a synergistic increase in the sterilization efficiency and allows for the use of much lower sterilant amounts and sterilization cycle times than would be expected from using the conditioning agent and the sterilant in combination. | 2021-12-02 |
20210369900 | HYDROGEN PEROXIDE FOAM GENERATING APPARATUS AND RELATED METHOD - An apparatus for generating a powerful oxidative hydrogen peroxide foam and chemically stable application process comprises separate supply lines for respectively conveying liquid hydrogen peroxide and liquid foaming agent from separate storage receptacles, a mixer for mixing the liquid hydrogen peroxide and foaming agent once combined together, an air supply line for aerating the foamable liquid hydrogen peroxide mixture, and a foam generating device for mechanically agitating the aerated foamable liquid hydrogen peroxide mixture to form the hydrogen peroxide foam for subsequent discharge to a substrate. There is also disclosed a related method for generating the hydrogen peroxide foam. | 2021-12-02 |
20210369901 | MOBILE DEVICE HAVING AN INTEGRATED DISINFECTING DEVICE FOR AIRCRAFT CABINS - A mobile device having an integrated disinfecting device for aircraft cabins, having a base having an upper side and, on a lower side, rotatably mounted wheels for moving the base on a floor; a frame fastenable to an upper side of the base; a dispenser unit which is coupled to the frame and configured to discharge on demand disinfectant in a metered manner at a front side; a supply unit coupled to the frame and configured to provide at least the disinfectant; wherein the dispenser unit is configured to be movable between a stowage state and a use state; and wherein the frame and/or the disinfecting device in the stowage state have/has a size which does not substantially exceed a size of a full-size cabin trolley. | 2021-12-02 |
20210369902 | COSMETICS CONTAINER, INNER LID, TUBULAR MEMBER, ROD-SHAPED MEMBER, AND MAIN BODY SIDE INNER LID - [Problem to be Solved] | 2021-12-02 |
20210369903 | MEMS-Based Virus Treatment - A microelectromechanical device utilizing one or more micropumps embedded in a mouthguard for treatment and detection of viruses in a person's mouth. The micropump pumps saliva through the device where it can, for example, be treated with heat to destroy viruses in the saliva. In another embodiment the device can be used to detect the presence of virus in the saliva utilizing DNA PCR or chronoamperometry. | 2021-12-02 |
20210369904 | AROMA GENERATOR - There is provided a novel aroma generator. | 2021-12-02 |
20210369905 | WHITE LIGHT LED LIGHT BULBS FOR AMBIENT LIGHTING AND PATHOGEN INACTIVATION - Consumable and replaceable light bulbs that emit white light to provide ambient lighting and also emit UV light for pathogen inactivation. The white light and the UV light may be emitted simultaneously or the light bulb can be controlled to emit the white light and the UV light at separate times. The UV light emitted by the light bulbs has a wavelength and output power that is safe for humans and pets and the UV light inactivates pathogens over relatively prolonged exposure periods. The light bulbs described herein can be used in place of conventional light bulbs, for example in a room of a home, office building or other human occupied space. Humans can remain in the space when the light bulb(s) is on without being harmed by the UV light. | 2021-12-02 |
20210369906 | Ultraviolet Air Irradiation System and Ultraviolet Air Irradiation Process - The present invention is a compact and portable personal ultraviolet air irradiation system having an ultraviolet air irradiation unit, a breathing tube, and a face mask. Unfiltered air passes through the ultraviolet air irradiation unit and is purified to ensure biological material has been neutralized by utilizing UV LEDs in the germicidal wavelengths of 100-280 nm. The ultraviolet air irradiation unit may further purify air of air particulates, gases, vapors, and biological material by utilizing a HEPA filter. The ultraviolet air irradiation unit may provide variable pressure to the mask to meet the breathing demands of the user. Flow through the ultraviolet irradiation unit may be reversible to irradiate the exhalations of a user who may be infected with a virus or other disease spread through exhalations. | 2021-12-02 |
20210369907 | DEVICE FOR DUAL MODE DISINFECTION IN A VEHICLE INTERIOR - A device providing dual mode ultraviolet (UV) disinfection includes a housing for one or more light sources therein operating in the UV-C spectrum. A dynamically moveable shutter assembly is used for disinfecting air moving through the housing, or directing light from light source to a designated area of a motor vehicle interior. | 2021-12-02 |
20210369908 | METHOD FOR DUAL MODE DISINFECTION IN A VEHICLE INTERIOR - A method for providing dual mode UV automotive disinfection includes the step of providing one or more UV light sources and moving automotive cabin air in proximity to the light sources. A shutter is configured in proximity to the light source in either an open or closed position where operation of the light source(s), motor and shutter are controlled where the light sources operate in a first mode by disinfecting cabin air in proximity to the light source or in a second mode using the at least one light source to irradiate cabin surfaces. | 2021-12-02 |
20210369909 | POWDER TYPE HEMOSTATIC COMPOSITION AND METHOD FOR PREPARING THE SAME - The present invention relates to a powder type hemostatic composition and method for preparing the same, and more specifically, to powder aggregate having porosity obtained by combining powder of biocompatible hemostatic material with a binder and a method for preparing the same, and a powder type hemostatic composition which comprises the powder aggregate and shows improved hemostatic performance as compared with simple powder hemostatic agents, and can be used to a large surface area for hemostasis, or to narrow, thin or other sites to which approach for hemostasis is difficult. | 2021-12-02 |
20210369910 | METHODS OF WOUND HEALING WITH SERP-1 POLYPEPTIDES - Disclosed herein are topical compositions for treating wounds. The topically compositions include a Serp-1 polypeptide or a nucleic acid encoding a Serp-1 polypeptide. Also disclosed are methods of treating a wound in subject. The methods include administering a topical formulation that includes a Serp-1 polypeptide or a nucleic acid encoding a Serp-1 polypeptide to the wound. | 2021-12-02 |
20210369911 | HYDROGEL COMPOSITIONS - A crosslinkable composition comprises: A1) at least one multifunctional isocyanate-terminated urethane prepolymer comprising between 1 and 16 isocyanate functionalities on average, the prepolymer being a product of the reaction of a diisocyanate, a triisocyanate or a polyisocyanate with a functionality strictly greater than 3, with a polyol comprising 1 to 8 hydroxyl groups; and/or A2) at least one mono, di or polyisocyanate and/or an oligoglycerol; with B) at least one macropolyol chosen from: B1) oligoglycerols with an average degree of polymerisation less than or equal to 7, B2) glycerol dendrimers, B3) linear, branched or hyperbranched polyglycerols with a degree of polymerisation greater than or equal to 8, B4) mixtures of hyperbranched polyglycerols and linear, branched or hyperbranched oligoglycerols, with a degree of polymerisation of between 2 and 7, optionally functionalised. | 2021-12-02 |
20210369912 | 2D AND 3D BIOSCAFFOLD EXTRACELLULAR STRUCTURAL UNIT AND TISSUE STRUCTURE DESIGN AND METHODS OF MANUFACTURE - A bioscaffold structure is provided, the bioscaffold comprising a plurality of connected unit cells, each unit cell comprising a plurality of filaments composed of an extracellular material containing Collagen I and Collagen III, wherein each of the plurality of unit cells includes at least one opening connected to an internal volume. | 2021-12-02 |
20210369913 | SUSTAINED RELEASE INJECTABLE FORMULATION CONTAINING A POLY L LACTIC ACID FILLER AND A HYALURONIC ACID FILLER CONJUGATE AND A METHOD FOR PREPARING THE SAME - Disclosed are a sustained-release injection formulation containing a biodegradable polymer double microcapsule that contains a conjugate of poly-L-lactic acid (hereinafter referred to as “PLLA”) filler and hyaluronic acid (hereinafter referred to as “HA”) and is capable of controlling the release rate of PLLA, and a method of preparing the same. | 2021-12-02 |
20210369914 | ULTRAHIGH DUCTILITY, NOVEL Mg-Li BASED ALLOYS FOR BIOMEDICAL APPLICATIONS - The invention relates to compositions including magnesium-lithium alloys containing various alloying elements suitable for medical implant devices. The devices may be constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also relates to methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, such as but not limited to, orthopedic, dental, craniofacial and cardiovascular surgery. | 2021-12-02 |
20210369915 | TRIPLE-NETWORK HYDROGEL IMPLANTS FOR REPAIR OF CARTILAGE - Artificial cartilage materials for repair and replacement of cartilage (e.g., load-bearing, articular cartilage). The artificial cartilage materials described herein include triple-network hydrogels including a cross-linked fiber network (e.g., a bacterial cellulose nanofiber network) and a double-network hydrogel (e.g., a double-network hydrogel including polfacrylamide-methyl propyl sulfonic acid). The artificial cartilage may be coated onto or formed into an implant (e.g., plug). The artificial cartilage may include a surface macroporosity, e.g., 0.1-300 micrometers diameter. Also described herein are methods of forming and methods of using the triple-network hydrogel artificial cartilage materials. | 2021-12-02 |
20210369916 | TERMINALLY STERILIZED DEMINERALIZED BONE MATERIAL (DBM) AND SYSTEM AND METHODS FOR PROTECTING DBM AGAINST TERMINAL IRRADIATION - Terminally sterilized demineralized bone material (DBM) and systems and methods for protecting DBM against damage caused by terminal irradiation are described. A method includes providing the DBM, which includes at least a collagen matrix and natural, non-collagenous protein. The DBM is soaked in a mixture of glycerol and a solvent to remove and replace water in the collagen matrix of the DBM. The DBM is dried, after soaking, to form a protected DBM. | 2021-12-02 |
20210369917 | MODULAR BIOFABRICATION PLATFORM FOR DIVERSE TISSUE ENGINEERING APPLICATIONS AND RELATED METHOD THEREOF - System and method of bioprinting used to enable automated fabrication of various constructs with high reproducibility and scalability, while reducing costs and production timelines. The bioprinting applications provides a critical component to the further enrichment the overall biomanufacturing paradigm. The biofabrication of sheet-like implantable constructs and other construct types with cells deposited on both sides—a process that may be both scaffold and cell type agnostic, and furthermore, is amenable to many additional tissue engineering applications beyond skeletal muscle. | 2021-12-02 |
20210369918 | CELL SHEET FOR TRANSPLANTATION INTO LIVING BODY AND METHOD FOR PRODUCING SAME - A cell sheet for transplantation into a living body, containing MSCs having an average cell density of 3.0×10 | 2021-12-02 |
20210369919 | BONE GRAFTS INCLUDING OSTEOGENIC STEM CELLS, AND METHODS RELATING TO THE SAME - Bone grafts and constructs including stem cells are provided. Example bone grafts include osteogenic stem cells seeded on a scaffold of osteoconductive cortico-cancellous chips and/or osteoinductive demineralized bone. Example constructs include extracellular matrix on a synthetic scaffold, in which the ECM is secreted from MSCs seeded onto the synthetic scaffold. Also provided are methods of making the present bone grafts and scaffolds. Further provided are methods of promoting bone healing and treating wound healing, by administering the present bone grafts and constructs to a mammal in need thereof Also provided are kits that include the present bone grafts and/or constructs, or components thereof. | 2021-12-02 |
20210369920 | NASOLACRIMAL DUCT INSERTION MEMBER COMPRISING SHAPE MEMORY POLYMER - The present invention relates to a nasolacrimal duct insertion member comprising a shape memory polymer for treatment of nasolacrimal duct obstruction/stenosis, wherein the shape memory polymer comprises a crosslinkable functional group, such that the nasolacrimal duct insertion member has a melting point suitable for implantation into a living body. | 2021-12-02 |
20210369921 | Fluoropolymer Based Anti-Thrombotic Coatings - The present disclosure provides for medical devices comprising one or more components comprised of a fluoropolymer and/or perfluorinated polymer and a liquid comprised of one or more fluorinated and/or perfluorinated liquids, wherein at least a portion of a surface of the one or more components comprised of a fluoropolymer and/or perfluorinated polymer comprises a surface layer of the fluorinated and/or perfluorinated liquid. | 2021-12-02 |
20210369922 | VISCOELASTIC COMPOSITION - The purpose of the present invention is to provide a viscoelastic composition having excellent operability, which is suitable for use in securing the field of view of an endoscope when opaque dark-colored liquid accumulates inside a canal and obstructs the field of view of the endoscope, the viscoelastic composition securing the field of view by pushing the liquid aside, and to provide a method for securing the field of view of an endoscope using the viscoelastic composition. The viscoelastic composition for securing the field of view of an endoscope comprises a substance having viscoelastic properties and water, preferably has a hardness of 550 N/m | 2021-12-02 |
20210369923 | RECOMBINANT HUMAN COLLAGEN-BASED MULTIFUNCTIONAL STENT COATING AND PREPARATION METHOD THEREOF - A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials. | 2021-12-02 |
20210369924 | METHOD DEVICE THAT PREVENTS AIR LEAKAGE AND ENVIRONMENTAL CONTAMINATION DURING TUBE REMOVAL FROM PATIENT - A medical device for use with an associated tube inserted into an incision formed in skin or tissue of a patient includes a dressing including an opening sized to receive and allow movement of the associated tube. A valve is operatively connected with the opening of the dressing and includes a main body; and an opening formed in a portion of the main body. The opening is sized and dimensioned to accommodate the surgical tube. | 2021-12-02 |
20210369925 | CHEST TUBE AIR LEAK DETECTION SYSTEM - A gas collection unit for use in monitoring and tracking a discharge of air from a patient includes a housing, a set of valves, and a plurality of tubes. The housing contains a first chamber, a second chamber, and a third chamber wherein the chambers are in fluid communication with one another. The housing includes a fluid in the first chamber and the second chamber. The first valve regulates the passage of air flow from the patient into the first chamber and is located within a first tube coupled to the housing. The second valve is in communication with the second chamber. The second valve being configured to regulate the passage of air exiting the first chamber. The second chamber is subjected to a suction. The gas collection unit is operable with an air collection device as a retrofitted item. | 2021-12-02 |
20210369926 | A PUMP ARRANGEMENT, CONFIGURED TO BE USED WITH A DOUBLE BREAST PUMP DEVICE - In a pump arrangement ( | 2021-12-02 |
20210369927 | Breast Pump - A breast pump is disclosed. According to an aspect of the present invention, there is provided a breast pump comprising a contact housing comprising a protruding part configured to correspond to a mother's nipple and extend toward the front; a first space-defining member coupled to the protruding part to define a first inner space; a second space-defining member defining a second inner space linked with the first inner space; a storage housing comprising a coupling hole corresponding to the second inner space, the storage housing being coupled with the contact housing; a lid coupled to cover the second inner space through the coupling hole of the storage housing, the lid comprising an air passage; a flow separation membrane configured to divide and separate the second inner space into a first portion and a second portion, the first portion linked with the first inner space, the second portion linked with the air passage; and an attachable pump module on the lid to suck air of the second portion through the air passage, wherein the attachable pump module is integrally coupled with the lid to be attached to and detached from the coupling hole. | 2021-12-02 |
20210369928 | MEDICAL SYSTEM FOR MONITORING USING RADAR WAVES - A medical system, usable for example in connection with a dialysis apparatus, may utilize radar waves for monitoring a patient, a medical area, or an object. The medical system includes at least one sending device for sending radar waves, and at least one receiving device for receiving reflected radar waves. The medical system further includes an evaluation unit for evaluating the reflected radar waves which have been received by the at least one receiving device, resulting in obtaining a result, and an output device for outputting the result or a signal based on the result. | 2021-12-02 |
20210369929 | SERVICING REGIME FOR A DISPOSABLE SET OF A MEDICAL FLUID THERAPY MACHINE - A servicing regime for a disposable set of a medical fluid therapy machine is disclosed. In an example, a medical fluid delivery system includes a medical fluid therapy machine operating with a disposable set over multiple treatments to mix for each treatment at least one concentrate with purified water to form a medical fluid. The medical fluid delivery system also includes a sensor configured to measure an accuracy of the medical fluid mixed by the medical fluid therapy machine. The sensor is configured to produce a mixing accuracy output. The medical fluid delivery system further includes a computer programmed to analyze the mixing accuracy output provided by the sensor to determine whether the disposable set needs to be replaced. | 2021-12-02 |
20210369930 | COMBINATION WEARABLE AND STATIONARY DIALYSIS SYSTEM WITH ULTRAFILTRATE MODULE - The present disclosure includes systems and methods for hemodialysis, such as including a first dialysis module and an auxiliary module detachably connectable to the first dialysis module. The first dialysis module can include a dialyzer, a blood circuit, a dialysate circuit, and a sorbent. The auxiliary module can include an ultrafiltrate collector operably couplable to the dialysate circuit for removing excess fluid therefrom. | 2021-12-02 |
20210369931 | BLOOD PROCESSING SYSTEM - A blood gas management device comprises a blood passage having a gas-blood interface with a plurality of gas passages, and is arranged to direct a flow of supply gas from the gas inlets through the gas passages to the gas outlets, and to allow a flow of blood in a blood flow path through the blood passage to thereby permit an exchange of blood gas with the supply gas via the interface. The blood gas management device comprises a supply gas distribution arrangement allowing the supply gas to be provided from different directions relative to the blood flow path. This provides an improved gas-transfer gradient at different locations along the gas passage. | 2021-12-02 |
20210369932 | MULTI-FUNCTIONAL PERITONEAL DIALYSIS MOBILE CART - A mobile dialysis therapy cart includes a top shelf; a cycler compartment positioned below the top shelf, the cycler compartment sized and shaped to house an APD cycler; a fluid bag management compartment sized and shaped to house at least two fluid bags; a drain compartment positioned below the fluid bag management compartment; and a plurality of wheels. The cart may include a heating device associated with the fluid bag management compartment and/or a sanitizing light source for sanitizing a location of a disposable set associated with the fluid bags. | 2021-12-02 |
20210369933 | METHOD FOR REMOVAL OF VIRUSES FROM BLOOD BY LECTIN AFFINITY HEMODIALYSIS - The present invention relates to a method for using lectins that bind to pathogens having high mannose surface glycoproteins or fragments thereof which contain high mannose glycoproteins, to remove them from infected blood or plasma in an extracorporeal setting. Accordingly, the present invention provides a method for reducing viral load in an individual comprising the steps of obtaining blood or plasma from the individual, passing the blood or plasma through a porous hollow fiber membrane wherein lectin molecules are immobilized within the porous exterior portion of the membrane, collecting pass-through blood or plasma and reinfusing the pass-through blood or plasma into the individual. | 2021-12-02 |
20210369934 | FILTERING SYSTEMS AND FILTERING MANIFOLDS FOR USE WITH FILTERING SYSTEMS - Filtering device for filtering cerebrospinal fluid are disclosed. An example filtering device may include a filter housing having an inlet for receiving cerebrospinal fluid from a patient and an outlet for returning filtered cerebrospinal fluid to the patient. The filter housing may include a plurality of layers coupled together and defining a fluid pathway therein between the inlet and the outlet. A filtering section may be defined within the filter housing along the fluid pathway. The filtering section may include a widened region of the fluid pathway that is configured to slow the passage of fluid therethrough. | 2021-12-02 |
20210369935 | SENSOR SYSTEM AND MEDICAL DEVICE - A sensor system ( | 2021-12-02 |
20210369936 | POSTPARTUM BLOOD LOSS COLLECTION AND MEASUREMENT DEVICE, AND METHOD OF USE - Devices and methods for collecting and measuring postpartum blood loss of a patient are disclosed. The device generally includes a tray that may be positioned under a patient and a basin configured to collect blood. The basin can include gradation markings to facilitate accurate, real-time measurements of the amount of blood that the patient has lost to guide decision making of medical personnel. | 2021-12-02 |
20210369937 | INTEGRATED SYSTEM FOR ASSESSING WOUND EXUDATES - An integrated system for assessing wound exudates from the wound of a patient is described. The system may contain functionality to detect, process and report various wound parameters. The system also may make treatment determinations based on these findings. The system may detect one or more physiological values of the wound exudates from the wound of the patient. The system may means for comparing the one or more detected physiological values to predetermined physiological values in order to obtain a comparison result in real time. The system may include a processor | 2021-12-02 |
20210369938 | INTEGRATED SYSTEM FOR ASSESSING WOUND EXUDATES - An integrated system for assessing wound exudates from the wound of a patient is described. The system may contain functionality to detect, process and report various wound parameters. The system also may make treatment determinations based on these findings. The system may detect one or more physiological values of the wound exudates from the wound of the patient. The system may means for comparing the one or more detected physiological values to predetermined physiological values in order to obtain a comparison result in real time. The system may include a processor | 2021-12-02 |
20210369939 | Suction Device for Surgical Instruments - A suction device is shown and described. The suction device includes a body, an input port configured to receive a flow of matter, a suction port, and a suction lumen that couples the suction port to the input port. In some embodiments the suction device is configured to couple with a surgical instrument for use in a surgical procedure. | 2021-12-02 |
20210369940 | MODULAR, MULTI-SPECIALTY FLUID PUMP - The present disclosure is directed to a modular, multi-specialty pump system. The pump system includes a pump console with a motor and a sensor and a removable pump cassette attached to the pump console. The pump cassette includes a cassette identifier and the sensor can detect the cassette identifier and adjust at least one operating parameter of the motor depending on the detected cassette identifier of the pump cassette. | 2021-12-02 |
20210369941 | SYSTEM AND METHOD FOR ESTIMATION AND CONTROL OF COMPLIANCE AND PRESSURE/VOLUME VARIATIONS WITHIN A BODY CAVITY - Systems and methods are provided for controlled infusion, effusion, and/or perfusion of biological/biocompatible liquid to and from a body cavity of a subject, and for continuous control of body cavity parameters, for example in neuro-intensive care. Systems and methods may relate to estimating compliance and pressure/volume changes within a body cavity. A bio-liquid replacement system may include a sensor for continuously measuring at least one parameter associated with the cavity, a pump for infusing the liquid into and aspirating the liquid out of the cavity, a processing unit continuously calculating at least one physiological parameter based on the measured parameter, and defining a target parameter slightly offset from the physiological parameter, and a flow controller controlling said pump unit based on the target parameter and the induced offset such that continuous compensatory changes are induced in the liquid volume. The processing unit continuously estimates the body cavity compliance. | 2021-12-02 |
20210369942 | SYSTEMS AND METHODS FOR POSITIONING FLUID SUPPLY SYSTEM - Fluid supply systems and methods for therapeutic fluid delivery systems, including those used for negative pressure wound therapy (NPWT) systems and methods. | 2021-12-02 |
20210369943 | VESSEL AND DEVICE FOR RECOVERING AND PREPARING ADIPOSE TISSUES - Disclosed is a vessel for recovering adipose tissues including a body sealed by a lid connectable to a first pipe with a suction cannula, and a second pipe with a suction pump. A removable adapter connects a lid including two orifices, each closed by a stopper that can be pierced or is pre-pierced and self-sealing, and a vent opening with a filter and removable plug. The connection adapter includes two rigid piercing tubes projecting from under the adapter, each piercing tube in continuous fluid relationship with a corresponding nipple projecting from the adapter, each nipple connectable to a corresponding pipe. The two sealed orifices of the lid and the adapter and piercing tubes are arranged so, when the connection adapter is applied to the lid, each piercing tube pierces a corresponding stopper and brings each nipple into correspondence, in a sealed manner, with the internal volume of the vessel. | 2021-12-02 |
20210369944 | SECURING CONTROL OF SETTINGS OF WOUND THERAPY APPARATUSES - Embodiments of secure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, the apparatus includes a pressure source, a user interface, and a locking mechanism. The locking mechanism can be in one of at least two states, the at least two states including a first state in which the locking mechanism physically prevents user adjustment of one or more operational parameters with the user interface and a second state in which the locking mechanism does not physically prevent user adjustment of the one or more operational parameters with the user interface. The locking mechanism can include an authentication key and a receiver configured to receive an authentication input, which may be compared to the authentication key. Providing a sufficiently matching authentication input can transition the locking mechanism from the first state to the second state, permitting adjustments to the one or more operational parameters. | 2021-12-02 |
20210369945 | PACKAGING FOR A MEDICAMENT CONTAINER - The present disclosure relates to a packaging for a medicament container, wherein the medicament container comprises at least one distal container abutment section and at least one proximal container abutment section, the packaging comprising: a bottom and a sidewall structure connected to the bottom, the bottom and the sidewall structure confining a storage space configured to accommodate at least one medicament container, at least one distal packaging abutment section, and at least one proximal packaging abutment section, wherein the at least one distal packaging abutment section is integrated into or arranged at one of the sidewall structure and the bottom and configured to abut with the at least one distal container abutment section, wherein the at least one proximal packaging abutment section is integrated into or arranged at the sidewall structure and configured to abut with the at least one proximal container abutment section. | 2021-12-02 |
20210369946 | RADIOEMBOLIZATION DELIVERY DEVICE - A delivery assembly includes a console including a vial containment region and a vial engagement mechanism extending from the console within the vial containment region. The engagement mechanism is configured to engage a vial assembly. The delivery assembly further includes a sled assembly removably coupled to the console at the vial containment region and a safety shield removably coupled to the console over the vial containment region such that the vial engagement mechanism and the sled assembly are encapsulated within the safety shield when the safety shield is coupled thereto. The sled assembly, the vial assembly, and the safety shield are configured to inhibit radioactive emissions from within the vial containment region. | 2021-12-02 |
20210369947 | DELIVERY DEVICE - A delivery device for intravenous delivery of microparticles to a patient. The delivery device is fluidly connectable to (i) a first source of an injection medium and (ii) a second source of an injection medium. The delivery device includes: a first fluid inlet fluidly connectable to the first source of the injection medium, a fluid outlet, a fluid mixer fluidly connecting the first fluid inlet to the fluid outlet, a second fluid inlet fluidly connectable to the second source of the injection medium, and a source of microparticles fluidly connecting the second fluid inlet to the fluid mixer. When fluid flows from the second source of the injection medium into the delivery device: the second injection medium fluidly drives microparticles from the source of microparticles into the fluid mixer, and the fluid outlet dispenses to the patient an injection medium that includes the microparticles. | 2021-12-02 |
20210369948 | ANTI-BUBBLE INFUSION DRIP CHAMBER - The present invention discloses an anti-bubble infusion drip chamber. The anti-bubble infusion drip chamber comprises a drip chamber main body; the drip chamber main body has an upper portion and a lower portion, namely a drip chamber portion arranged on the upper portion and a filtering portion arranged on the lower portion; the filtering portion is provided with a liquid storage cavity communicated with an inner cavity of the drip chamber portion, and a liquid medicine filter and an air filter which are arranged on two sides of the liquid storage cavity; a liquid medicine flow channel is arranged on the side wall of the filter and is provided with a liquid inlet and a liquid outlet; the liquid inlet is formed above the liquid outlet; a liquid medicine filter membrane is arranged between the liquid inlet of the flow channel and the liquid storage cavity; and an air filter is arranged on the drip chamber main body on at least one side of the filter membrane. A horizontally-placed liquid medicine filter membrane in the traditional drip chamber can cause unsmooth flow of liquid medicine due to surface tension of the liquid medicine and accumulation of impurities. By making an improvement on the drip chamber, the liquid medicine filter membrane is vertically or obliquely arranged, so that on one hand, the impurities can be prevented from being accumulated on the surface of the filter membrane, and on the other hand, the surface tension of the liquid medicine can be destroyed. | 2021-12-02 |
20210369949 | SYSTEM AND METHOD FOR SUBSTANCE DELIVERY - A system for delivering a fluid to tissue and a method of using same are provided. The system includes a tissue clip for securing a tissue fold and a tissue puncturing device attachable to the tissue clip. The system further includes a mechanism for sensing the tissue fold and releasing a safety mechanism in the tissue puncturing device so as to enable manual deployment of a tissue puncturing element from the tissue puncturing device. | 2021-12-02 |
20210369950 | CHEMICAL LIQUID INJECTING APPARATUS - In a chemical liquid injection conduit, there is a need to prevent a backflow of body fluid of a subject reaching the inside of a common conduit portion. This is solved by the chemical liquid injecting apparatus that includes: a common conduit portion that flows a chemical liquid from a chemical liquid injector to a replaceable conduit portion; a control device that controls the chemical liquid injector; and a flow blocking unit that is arranged inside the replaceable conduit or in a conduit of a boundary portion between the replaceable conduit and the common conduit portion, and by receiving a command from the control device, is switchable between an open state allowing a flow of the chemical liquid and a closed state blocking a flow of the chemical liquid. | 2021-12-02 |
20210369951 | SYRINGE INFUSION DEVICES AND SYSTEMS FOR DELIVERY OF ACTIVE AGENTS - A pump device ( | 2021-12-02 |
20210369952 | DRUG SOLUTION DELIVERY APPARATUS - This drug solution delivery apparatus includes a pump main body, a cartridge main body having a plunger operation unit, and a controller for controlling a drive unit. The plunger operation unit has a slide nut and a rib for restricting movement of the slide nut. The drug solution delivery apparatus further includes an attachment detection sensor for detecting contact of the slide nut with the rib. The controller causes the drive unit to drive in reverse, and determines whether the cartridge main body is new or previously used on the basis of a detection signal of the attachment detection sensor. | 2021-12-02 |
20210369953 | System For Syringe Engagement To An Injector - An injector system for injecting fluid includes a syringe and an injector. The syringe includes a body and a plunger movably disposed within the body. The plunger has at least one flexible leg extending toward the rearward end of the body. The injector has a housing with a front plate, a drive member at least partially disposed within the housing and operable to engage the plunger, and a syringe release assembly operable to release the syringe. The syringe assembly includes a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing and a plunger release tube surrounding at least a portion of the drive member. The plunger release tube has a first end rotationally engaged with the syringe release gear. Rotation of the syringe release assembly releases the at least one flexible leg from the drive member. | 2021-12-02 |
20210369954 | INFUSION PUMP SYSTEMS AND METHODS FOR ADMINISTRATION SETS - An LVP that provides peristaltic pumping to removably couplable administration set tubing assemblies supplying medical infusate. The LVP includes a housing, a drive-train assembly, and a controller. The housing includes an assembly receptacle configured to receive an administration set tubing assembly. The drive-train assembly provides mechanical peristaltic movement within the assembly receptacle. The drive-train assembly includes a stepper motor located within the housing and a camshaft assembly, driven by the stepper motor and at least partially extending into the assembly receptacle. The camshaft assembly includes a unitary camshaft and a plurality of tube engaging members that cooperatively move according to rotation of the unitary camshaft. Further, the controller is located within the housing that controls operation of the stepper motor and the camshaft assembly. | 2021-12-02 |
20210369955 | MULTIPLE INFUSION CHANNEL DATA GRAPHICAL USER INTERFACE - Data is received that characterizes infusions administered to a patient among each of a plurality of infusion channels. Thereafter, a plurality of infusion events and respective event times are identified based on the received data. A temporal view of the infusion events can then be displayed in a graphical user interface and/or the temporal view of the infusion events can form part of a report. The temporal view segregates each channel into a separate swim lane with each swim lane visualizing infusion events for the corresponding channel at the respective event times. Related apparatus, systems, techniques and articles are also described. | 2021-12-02 |
20210369956 | INFUSION PUMP FLOW RATE CONTROL - Methods and systems for infusing a user. An infusion pump includes a housing with an elastic component configured to expand and store potential energy. The infusion pump includes a first tube fluidically coupled to an outlet of the housing. The first tube is configured to conduct the fluid from the housing at a first flow rate. The infusion pump includes an air filter fluidically coupled to a distal end of the first tube via an air filter inlet. The infusion pump includes a second tube fluidically coupled to the air filter via an air filter outlet. The second tube is configured to adjust the first flow rate of the fluid conducted from the housing to a second flow rate. The infusion pump further includes one or more components for distributing the fluid to a user, the one or more components fluidically coupled to an outlet of the second tube. | 2021-12-02 |
20210369957 | DRUG DELIVERY DEVICE WITH NEEDLE ACTUATION MECHANISM - A drug delivery device ( | 2021-12-02 |
20210369958 | POOLING DEVICE FOR SINGLE OR MULTIPLE MEDICAL CONTAINERS - A medicinal fluid pooling device may be used to pool multiple containers of medicinal fluid to facilitate administration of the medicinal fluid to a patient. A medicinal pooling device may include spikes covered by spike sheaths which are pierced when a container of medicinal fluid is inserted into the medicinal pooling device. The medicinal pooling device may also include a cover configured to cover the spikes. The medicinal pooling device may also include a fluidic interface which may be used to fluidly connect the medicinal pooling device to an infusion pump or syringe. | 2021-12-02 |
20210369959 | REAL TIME DRIP CHAMBER MONITOR - Drip chamber detection assemblies for intravenous sets used with an infusion pump are provided. A drip chamber detection assembly includes a sensor coupled to a drip chamber. The sensor is positioned to generate signals related to the fluid level within the drip chamber. The signal data is transmitted to an infusion pump or a controller. A fluid level status or condition is determined and used for closed loop control of the infusion system, which generates an alarm and/or stops the infusion pump based on abnormal conditions. Methods of operating drip chamber detection assemblies are also provided. | 2021-12-02 |
20210369960 | MODULAR INTRAVENOUS ASSEMBLY - Modular intravenous (IV) assemblies are provided. The modular IV assembly includes a drip chamber having a body and an inlet connector, a base housing coupled directly to a base portion of the drip chamber, the base housing having an inlet port in fluid connection with the drip chamber and a flow path cavity in fluid connection with the inlet port and a flow control assembly coupled directly to a first portion of the base housing. Any of a filter assembly, an anti-run dry member, a check valve and an air vent assembly may be included in the modular IV assembly. IV sets and methods of use are also provided. | 2021-12-02 |
20210369961 | Intravenous Fluid Delivery System and Apparatus - An intravenous fluid delivery apparatus (IFDA) includes a body having two or more docks, wherein each dock includes a dock outlet and is configured to engage with a container. The IFDA further includes a fluid interface having two or more interface inlets and an interface outlet, wherein the two or more interface inlets are in fluid communication with the interface outlet, and two or more supply lines, each supply line disposed between one of the dock outlets and one of the interface inlets, wherein the interface outlet is configured to connect with an intravenous line. | 2021-12-02 |
20210369962 | INFUSION PUMP SENSING SYSTEM - Force sensing assemblies for an infusion pump are provided. A force sensing assembly includes a processor and an occlusion sensor coupled to the processor. The occlusion sensor is positioned opposed to an occluder valve when the platen is closed. The force sensing assembly measures one or more forces exerted on a fluid tube during a pump cycle. Infusion pump assemblies, methods of operating an infusion pump with a force sensing assembly, systems for controlling an infusion pump and an infusion device are also provided. | 2021-12-02 |
20210369963 | INTEGRATED LIQUID FLOW CLOSED LOOP SENSING AND CONTROL - An integrated intravenous (IV) administration set includes a flow stop having a tubing fitment and a housing, the flow stop configured, in a first position, to prevent a flow of a fluid through the tubing, and in a second position, to permit the flow of the fluid through the tubing, the tubing fitment comprising a protrusion configured to receive a tubing. The IV administration set also includes an electronic flow sensor disposed within the housing, the electronic flow sensor configured to measure a flow of a fluid in the tubing, and one or more conductive connections configured within the housing and configured to provide electrical power to the electronic flow sensor. The flow stop is shaped to be loaded and engaged to a receptacle of an infusion device, and shaped to cause, when loaded and engaged, the one or more conductive connections to engage with a corresponding conductive connection provided by the infusion device to activate the flow sensor based on a power flow from the infusion device. | 2021-12-02 |
20210369964 | Arrangement for Detecting a Position of a Plunger - The invention relates to an arrangement for detecting a position of a plunger ( | 2021-12-02 |
20210369965 | PROCESS AND AUTOINJECTOR DEVICE FOR INJECTIONS WITH INCREASED PATIENT COMFORT - The invention provides methods and apparatus for injecting a medicine, especially a highly viscous medicine. Conventional methods and apparatus for injecting viscous medicines suffers from a variety of problems such as excessive force during the initial needle insertion and initial injection. In an inventive method, during the initial phase of the injection, energy is stored in a torsion spring that is subsequently released during a later stage of the injection. The present invention also provides for an improved autoinjector; especially via the use of a combination compression and torsion spring that powers the injection through controlling force applied to plunger via a screw flange or nut having pins that ride in a prescribed path down the length of the autoinjector. | 2021-12-02 |
20210369966 | Drug Delivery Device - The present disclosure relates to an audible and/or tactile indicator for use with a drug delivery device including a resilient force member configured to reside in two or more states having two or more different conformations, wherein in a relaxed state, the resilient force member is relaxed in a first conformation, wherein in a biased state, the resilient force member is biased to store energy in a second conformation different to the first conformation, wherein the resilient force member releases stored energy to generate an audible signal when changing from the biased state into the relaxed state due to a transition from the second conformation to the first conformation, wherein the resilient force member is bent by a certain angle about a longitudinal axis forming a longitudinal round fold with two adjacent angled wing-shaped sections. | 2021-12-02 |