49th week of 2020 patent applcation highlights part 12 |
Patent application number | Title | Published |
20200376189 | DOSING UNIT REFILLING SCHEDULING - A method for managing refilling a first reservoir of an ambulatory infusion system from a first container that stores a first drug and for managing refilling a second reservoir of the ambulatory infusion system out of a second container that stores a second drug is disclosed. The method includes repeatedly and automatically carrying out a filling volume assessment routine, which involves determining the expected infusion of the first drug and the second drug between the present time t | 2020-12-03 |
20200376190 | OCCLUSION DETECTION SYSTEM AND METHOD - A method, computer program product, and infusion pump assembly for determining a first rate-of-change force reading that corresponds to the delivery of a first dose of an infusible fluid via an infusion pump assembly. At least a second rate-of-change force reading is determined that corresponds to the delivery of at least a second dose of the infusible fluid via the infusion pump assembly. An average rate-of-change force reading is determined based, at least in part upon the first rate-of-change force reading and the at least a second rate-of-change force reading. | 2020-12-03 |
20200376191 | RATCHET DRIVE FOR ON BODY DELIVERY SYSTEM - Ratchet-based drive systems for more reliable and safer drug delivery are provided. The ratchet-based drive systems restrict angular movement and/or linear movement of components that cause a plunger to expel a liquid drug from a drug container. Movement of the components can be restricted to correspond to a predetermined or desired portion of the liquid drug. In the case that control of the drive system is lost or fails, the maximum amount of drug that could be delivered is limited to a known amount, thereby reducing the likelihood of an overdose. | 2020-12-03 |
20200376192 | SELF-RIGHTING SYSTEMS, METHODS, AND RELATED COMPONENTS - Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self-actuating component. For example, the self-righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent (e.g., for delivery to a location internal to a subject). | 2020-12-03 |
20200376193 | PUNCTURE MEMBER DETACHMENT DETECTION APPARATUS, PUNCTURE MEMBER DETACHMENT DETECTION SYSTEM, AND PUNCTURE MEMBER DETACHMENT DETECTION METHOD - A puncture member detachment detection apparatus ( | 2020-12-03 |
20200376194 | LIQUID TRANSFER DEVICE WITH TELESCOPIC VIAL ADAPTER FOR USE WITH INFUSION LIQUID CONTAINER AND DISCRETE INJECTION VIAL - A liquid transfer device is described. The liquid transfer device comprising a vial adapter comprising a puncturing cannula for puncturing an injection vial stopper, an IV spike and a substitute IV port holder for receiving a substitute IV port, and a flow control member port. The IV spike, the substitute IV port holder and the puncturing cannula are in flow communication with the flow control member port. The liquid transfer device comprising a flow control member sealingly inserted in the flow control member port. Rotation of the flow control member between a plurality of positions controls flow communication of the liquid transfer device, the positions comprising a mixing position for enabling flow communication between the IV spike and the puncturing cannula; and an administering position for enabling flow communication between the IV spike and the substitute IV port holder. | 2020-12-03 |
20200376195 | Valve Assembly for Drug Delivery Device - A valve assembly for a drug delivery device includes a valve housing having a first side and a second side positioned opposite from the first side, a cannula having a first end and a second end positioned opposite the first end, a pierce plate having a body and a piercing member extending from the body, with the body defining a coiled elongate member, and a valve boot connected to the valve housing and defining an interior space. The valve boot is configured to move from a pre-use position where the first end of the cannula and the piercing member of the pierce plate are received within the interior space to a use position where the piercing member of the pierce plate and the first end of the cannula extend outside of the valve boot and the interior space. | 2020-12-03 |
20200376196 | DEFORMABLE VALVE MECHANISM FOR CONTROLLING FLUID DELIVERY - A valve for controlling delivery of fluid includes a valve seat comprising a fluid inlet, a fluid outlet, a well having a passage, and a valve membrane comprising a conical portion having a base and a tip. The conical portion is configured to fit within the passage of the valve seat. The valve membrane is configured to fluidly connect the fluid inlet to the fluid outlet when the valve membrane is in an undeformed position and fluidly disconnect the fluid inlet from the fluid outlet when the valve membrane is in a radially deformed position. | 2020-12-03 |
20200376197 | ADJUSTING INSULIN DELIVERY RATES - A method includes receiving up-to-date blood glucose data for a PWD, determining basal insulin dosages for the PWD based on a baseline basal rate, delivering the basal insulin dosages to the PWD, modifying a target blood glucose level based on variability of blood glucose data for the PWD, receiving a temporary override indicating a user preference to reduce the likelihood that the PWD has a hypoglycemic event or a user preference to reduce the likelihood that the PWD has a hyperglycemic event, determining a temporary target blood glucose level based on the input—greater than the modified blood glucose level if the preference is to reduce the likelihood of a hypoglycemic event—lower than the modified target blood glucose level if the preference is to reduce the likelihood that of a hyperglycemic event. The method includes delivering basal insulin for the temporary period of time based on the temporary target. | 2020-12-03 |
20200376198 | SYSTEM AND METHOD FOR HEALTH MONITORING BY AN EAR PIECE - A biosensor includes an optical circuit that obtains a plurality of photoplethysmography (PPG) signals from light at different wavelengths that is reflected from or transmitted through tissue of a user. A processing circuit determines a measurement value for a nitric oxide (NO) level in blood flow using first and second PPG signals and determines an insulin response from caloric intake using the measurement value for the NO level in blood flow. The first PPG signal is obtained from light at a wavelength having a high absorption coefficient for NO in blood flow and the second PPG signal is obtained from light at a second wavelength having a low absorption coefficient for NO in blood flow. The processing circuit also determines one or more phases of digestion using at least one or more of the plurality of PPG signals. | 2020-12-03 |
20200376199 | AUTO-INJECTION DEVICE - The present application discloses a device that is designed to inject into a user medicinal or non-medical substance upon activation. The device is light and compact, suitable for wearing or carrying by a user. The device comprises a needle, a syringe, and two sets of springs. The syringe comprises a plunger and a chamber for storing an injection substance. The needle is configured to be coaxial and in communication with the syringe. Each set of springs may comprise one or more springs. The first set of springs is configured to push the needle and the second set of springs is configured to move the plunger. In one exemplary embodiment, the device is enclosed in a sealed case and the device may be made to resemble a watch. | 2020-12-03 |
20200376200 | SEMI DISPOSABLE AUTO INJECTOR - An automatic injection device including a reusable driving assembly having a forward injection end and an engagement element and a disposable cassette assembly including an injectable liquid to he injected at an injection site, wherein the disposable cassette assembly is removably insertable into the reusable driving assembly at the forward injection end and is removably retained within the reusable driving assembly by snap fit engagement therewith, the snap fit engagement being effected at least partially by the engagement element, which is displaced rearwardly by insertion of the disposable cassette assembly in the reusable driving assembly. | 2020-12-03 |
20200376201 | Medicant Injection Device - A medicant injection device includes a compressible body, a tip, and an outer luer body. The compressible body has a proximal end, a distal end, and a plurality of bellows, and defines an inner cavity for holding a liquid medicant. The tip is positioned at the proximal end of the compressible body. The outer luer body includes internal threads, and is positioned over and engaged with the tip to form a first fitting therewith. The first fitting is configured to be connected with a second fitting. A medicant injection device includes a compressible body having first and second arms, a receptacle interconnected with the compressible body and defining an inner cavity, and a first fitting configured to engage a second fitting. The compressible body is configured to be compressed by forcing the distal end of the first and second arm toward each other. | 2020-12-03 |
20200376202 | PREFILLED CONTAINER SYSTEMS - A syringe assembly may include a plunger having a stopper. A barrel may be configured to receive the plunger at an open first end. A tip cap may be removably attached to the second end and may form a chamber within the barrel between the plunger and tip cap. The chamber may be configured to contain a sterilization sensitive material. The barrel may be formed of a plastic material having a high barrier property configured to create a barrier between the sterilization sensitive material and gases produced for sterilization purposes such that the sterilization sensitive material remains unchanged during a sterilization procedure. | 2020-12-03 |
20200376203 | CONNECTION MECHANISM FOR AN AUXILIARY MODULE - An auxiliary module for connecting to an injector for dispensing a medical substance comprises a housing having a retaining device, and a receiving unit having a retaining element, wherein the receiving unit is movable relative to the housing. The auxiliary module includes a retaining configuration, in which the receiving unit is immovably retained in the housing by the retaining device, and in which the retaining element can cooperate with the injector in such a way that the injector is retained by the receiving unit and the retaining element is locked by the housing. The auxiliary module also includes a release configuration, in which the receiving unit is released from the retaining device and the injector is released from the retaining element. The auxiliary module can be adjusted from the retaining configuration into the release configuration, and back again, by an adjustment movement of the receiving unit. | 2020-12-03 |
20200376204 | COVER FOR LIQUID DELIVERY SYSTEM WITH INTEGRATED PLUNGER POSITION SENSING USING FOCUSED OPTICAL BEAM AND LINEAR POTENTIOMETER - A sliding cover for a liquid delivery device, such as a cap ( | 2020-12-03 |
20200376205 | DOSAGE DETERMINATION USING ELECTRICAL CONDUCTIVITY IN AN INJECTION DEVICE - A dose setting mechanism for a drug delivery device is presented that includes one or more potentiometers whereby relative motion and distances traveled between components in the dose setting mechanism are determined by monitoring and measuring changes in electrical resistance using a measuring device in electrical communication with the one or more potentiometers. | 2020-12-03 |
20200376206 | GAS FEEDING APPARATUS, GAS FEEDING CONTROL METHOD AND STORAGE MEDIUM - A gas feeding apparatus includes first and second temperature sensors for measuring a temperature of an atmosphere that are disposed in a housing. The apparatus may also include a panel, a protrusion protruding forward from the panel, a first opening provided in the panel in a vicinity of the first temperature sensor, and a second opening provided in the panel in a vicinity of the second temperature sensor. The first temperature sensor and the second temperature sensor are separated by a predetermined distance in a horizontal direction and disposed below the protrusion. | 2020-12-03 |
20200376207 | CARTRIDGE HOUSING AND ATOMIZER FOR A PERSONAL VAPORIZING UNIT - A personal vapor inhaling unit is disclosed. An electronic flameless vapor inhaler unit that may simulate a cigarette has a cavity that receives a cartridge in the distal end of the inhaler unit. The cartridge brings a substance to be vaporized in contact with a wick. When the unit is activated, and the user provides suction, the substance to be vaporized is drawn out of the cartridge, through the wick, and is atomized by the wick into a cavity containing a heating element. The heating element vaporizes the atomized substance. The vapors then continue to be pulled by the user through a mouthpiece and mouthpiece cover where they may be inhaled. | 2020-12-03 |
20200376208 | AEROSOL DELIVERY SYSTEM - An aerosol delivery system including a first engagement mechanism, a first power supply, and a first vaporizer, wherein the first vaporizer is arranged to selectively receive power from the first power supply to generate a first aerosol from a first aerosol precursor material for user inhalation; and a second aerosol delivery device including a second engagement mechanism, a second power supply, and a second vaporizer, wherein the second vaporizer is arranged to selectively receive power from the second power supply to generate a second aerosol from a second aerosol precursor material for user inhalation; wherein the first engagement mechanism of the first aerosol delivery device and the second engagement mechanism of the second aerosol delivery device are arranged to releasably co-engage with one another to selectively couple the first aerosol delivery device to the second aerosol delivery device so the first aerosol delivery device and the second aerosol delivery device may be used together to deliver the first and second aerosols to a single user when they are coupled together and may be used independently to deliver the first and second aerosols to different users when they are not coupled together. | 2020-12-03 |
20200376209 | MEDICINAL INHALER DRIVE MECHANISM - A drive mechanism for a medicinal inhaler, the inhaler comprising: a patient port; a canister actuable by the drive mechanism to deliver a dose of medicament to the patient port, the drive mechanism comprising: a follower which moves between a first position in which the mechanism is primed for use and a second position in which the follower engages the canister to deliver a dose of medicament to the patient port, the follower being carried on a rocker plate which pivots as the follower moves between its first and second position, wherein the rocker plate engages a switch when the follower is in its second position to indicate that a dose of medicament has been delivered to the patient port. | 2020-12-03 |
20200376210 | VAPOR PROVISION CARTRIDGE AND SYSTEM - A cartridge for a vapor provision system including the cartridge and a control unit, wherein the cartridge includes a housing part having a mouthpiece end and an interface end, wherein the mouthpiece end includes a vapor outlet for the cartridge and the interface end includes an interface for coupling the cartridge to a control unit; an air channel extending from an air inlet in the housing part to the vapor outlet; a reservoir within the housing part containing liquid for vaporization, wherein an end of the reservoir at the interface end of the housing part is sealed by a resilient plug, wherein the reservoir includes a dividing wall between a first reservoir region on a side of the dividing wall facing the mouth piece end of the housing part and a second reservoir region on a side of the dividing wall facing the interface end of the housing part, wherein the dividing wall includes at least one fluid communication opening to provide fluid communication between the first reservoir region and the second reservoir region; and a liquid transport element arranged to transport liquid from the second region of the reservoir to a vaporizer for generating vapor in a vapor generation region for user inhalation. | 2020-12-03 |
20200376211 | AEROSOL PROVISION DEVICE AND APPARATUS FOR A VESSEL - An aerosol provision device for generating an inhalable aerosol comprises a housing containing a first chamber for containing a hot liquid. The housing also contains a second chamber for containing a substance that is heatable to generate the aerosol. The housing also contains a thermal energy transfer component for contacting the hot liquid when the hot liquid is contained in the first chamber to transfer thermal energy from the hot liquid to the substance when the substance is contained in the second chamber in order to heat the substance to generate the aerosol. The device comprises a mouthpiece comprising an outlet through which the aerosol may flow. | 2020-12-03 |
20200376212 | OIL-INFUSED ELASTOMERIC THERAPEUTIC DEVICE - A clip device is provided, which is configured to removably attach to a body part of a human or animal user. The clip is of an elastomeric, silicone-based material, and the material is configured to absorb an oil to infuse the clip with the oil. The oil is to be applied to a user through the clip when the clip is attached to the body part of the user. In some instances, the clip device is adapted to connect to the nose of the user by way of the user's nostrils. | 2020-12-03 |
20200376213 | MINIATURE AIR FILTRATION ASSEMBLY FOR A MEDICAL FIELD - The present invention is directed to an assembly and method of use thereof for reducing microbial load in an airway of a patient. The assembly includes a miniature vacuum unit. The miniature vacuum unit includes a housing, at least one air inlet configured in the housing for air intake; a vacuum motor for sucking the air through the at least one air inlet; vents configured in the housing for blowing the sucked air out of the housing, a filter media covering inner side of the vents, such as the sucked air passes through the filter media, the filter media configured to retain microbes suspended in the sucked air; and at least one suction tube. The suction tube is having a proximal end and a distal end, the proximal end of the at least one suction tube configured to sealably and releasably coupled to the at least one air inlet, a plurality of apertures configured in the wall of the suction tube near its distal end. The suction tube configured to be positioned within the mouth of the patient. | 2020-12-03 |
20200376214 | OSCILLATING POSITIVE EXPIRATORY PRESSURE DEVICE - An oscillating positive expiratory pressure device comprising a housing enclosing at least one chamber, a chamber inlet configured to receive exhaled air into the at least one chamber, and a chamber outlet configured to permit exhaled air to exit the at least one chamber. A channel is positioned in an exhalation flow path between the chamber inlet and the chamber outlet, with the channel being movably connected to a chamber of the at least one chamber. An air flow regulator is movable with respect to the channel between a first position, where the flow of air through the channel is restricted and a second position, where the flow of air through the channel is less restricted, the air flow regulator being configured to repeatedly move between the first position and the second position in response to a flow of exhaled air. | 2020-12-03 |
20200376215 | HUMIDIFICATION SYSTEM AND POSITIVE AIRWAY PRESSURE APPARATUS INCORPORATING SAME - Systems, apparatus, and methods for providing humidity in a positive airway pressure (PAP) device. In one embodiment, a humidifier is configured to periodically provide vapor to a flow of pressurized gas to produce flows of pressurized gas with added humidity. Each of the flows of pressurized gas with added humidity may be timed to reach a user interface primarily during a first portion of a breath cycle (e.g., during inspiration). Portions of the flow of pressurized gas that reach the user interface during a second portion of the breath cycle (e.g., during expiration) may include little or no added humidity. | 2020-12-03 |
20200376216 | AIRWAY CLEARANCE SYSTEM - An airway clearance system includes a bladder, a negative pressure relief valve, a positive pressure relief valve, and a port. The bladder is moveable between an expanded state and a compressed state, and defines a first volume in the expanded state and a second volume in the compressed state. The second volume is less than the first volume. The negative pressure relief valve is in fluid communication with the bladder and configured to supply fluid to the bladder from an atmosphere surrounding the bladder. The positive pressure relief valve is in fluid communication with the bladder and configured to supply fluid to the atmosphere from the bladder. The port is in fluid communication with the bladder and configured to supply fluid from the bladder when the bladder moves to the compressed state and to supply fluid to the bladder when the bladder moves to the expanded state. | 2020-12-03 |
20200376217 | BLOOD PRESSURE MEASURING APPARATUS, METHOD AND PROGRAM FOR MEASURING BLOOD PRESSURE, AND RESPIRATION ASSISTANCE APPARATUS - According to one embodiment, a blood pressure measuring apparatus includes a blood pressure measurement unit, a warning estimator, and a signal output unit. The measurement unit measures blood pressure of a target person. The estimator monitors variation of blood pressure measured by the measurement unit and estimates the variation of the blood pressure as a sign of a blood pressure increase associated with an onset of sleep apnea syndrome if the blood pressure continuously decreases to a preset threshold or lower for a predetermined time or longer. The output unit outputs a sign notification signal to outside of the apparatus if the sign is estimated by the estimator. | 2020-12-03 |
20200376218 | SYSTEM AND METHOD FOR USE OF ACOUSTIC REFLECTOMETRY INFORMATION IN VENTILATION DEVICES - The present disclosure relates to a system and method for use of acoustic reflectometry information in ventilation devices. The system and method includes a speaker to emit sound waves into an intubated endotracheal tube (“ETT”) and a microphone to detect returning acoustic reflections. In addition, the system and method includes a reflectometry device in communication with a ventilation device for analyzing timings and amplitudes of the returning acoustic reflections to determine a size of a passageway around an ETT tip, location and size of ETT obstructions, and relative movement of the ETT tip within a trachea. The reflectometry device is also configured to determine a resistance parameter representative of resistance to actual flow of air through the ETT based upon a function of the diameter of the ETT, length of the ETT, and percent obstruction of the ETT, where the resistance parameter is used to calculate the tracheal pressure, | 2020-12-03 |
20200376219 | Blind intubation device and related methodologies for endotracheal intubation - Disclosed is an apparatus and method to facilitate insertion of the endotracheal tube into the patient's trachea. | 2020-12-03 |
20200376220 | MASK AND FLOW GENERATOR SYSTEM - A system for delivering a pressurized flow of breathable gas to a patient includes a patient interface and a flow generator mounted on the patient interface. The patient interface is configured to contact the patient's head and includes a frame and a cushion supported by the frame and configured to sealingly connect the patient interface to the patient's face and form a chamber between the frame and the patient's face. An inlet port in the frame is configured to receive the pressurized flow of breathable gas. The flow generator is configured to generate the pressurized flow and is capable of creating a pressure of about 2-40 cm H | 2020-12-03 |
20200376221 | PATIENT INTERFACE - A patient interface includes a plenum chamber pressurisable to a therapeutic pressure above ambient air pressure, a seal-forming structure constructed and arranged to seal with a region of the patient's face surrounding an entrance to the patient's airways, a positioning and stabilising structure to provide a force to hold the seal-forming structure in a therapeutically effective position on the patient's head, a connection port configured to connect to an air circuit to direct a flow of air into the plenum chamber, and a vent structure to allow a continuous flow of gases exhaled by the patient from an interior of the plenum chamber to ambient, and the plenum chamber includes a superior portion, an inferior portion, and a flexible portion positioned between the superior portion and the inferior portion, the flexible portion being configured to allow the superior portion and the inferior portion to move relative to one another. | 2020-12-03 |
20200376222 | Patient Interface Systems - A patient interface structure for delivery of respiratory therapy to a patient includes a front plate configured to conform to the shape of the patient's face; a mouth cushion defining a breathing chamber and provided to the front plate and configured to seal around the patient's mouth; and a nasal cushion configured to seal the patient's nasal airways. The nasal cushion is supported by the mouth cushion, does not contact a bridge of the patient's nose in use, and extends at least partially into the breathing chamber. A patient interface system includes a patient interface structure and a patient interface structure positioning system configured to position, stabilize and secure the patient interface structure in sealing engagement with the patient's face. | 2020-12-03 |
20200376223 | Patient Interface Systems - A patient interface structure for delivery of respiratory therapy to a patient includes a front plate configured to conform to the shape of the patient's face; a mouth cushion defining a breathing chamber and provided to the front plate and configured to seal around the patient's mouth; and a nasal cushion configured to seal the patient's nasal airways. The nasal cushion is supported by the mouth cushion, does not contact a bridge of the patient's nose in use, and extends at least partially into the breathing chamber. A patient interface system includes a patient interface structure and a patient interface structure positioning system configured to position, stabilize and secure the patient interface structure in sealing engagement with the patient's face. | 2020-12-03 |
20200376224 | PIERCING ASSEMBLY AND BREATHING CONDUIT KIT - An assembly is configured to provide access to an interior volume of a breathing conduit. The assembly includes a piercing portion and a body portion. The piercing portion is configured to pierce through a wall of the breathing conduit to make an opening there through. The piercing portion is configured to be inserted through the opening, into the interior volume. The body portion includes a channel configured to provide fluid access to the interior volume. The assembly also includes a sealing configured to seal an area between the opening and the body portion. A breathing conduit kit includes a breathing conduit and an assembly. | 2020-12-03 |
20200376225 | LOCKING TUBE CLIP - A component useable with one or more tube comprises a body engageable with one or more external surface recesses of the one or more tubes. The component has a pair of jaws extending from the body for gripping an item. The component is configured, such that, in use, in a first orientation of the body relative to the respective tube(s) recesses, the component is movable along a length of the tube(s); and, in a second orientation of the body relative to the respective tube(s) recesses, the component is resistive to movement along a length of the tube(s). | 2020-12-03 |
20200376226 | CONFIGURABLE OXYGEN CONCENTRATOR AND RELATED METHOD - A configurable oxygen concentrator for providing various flow rates and volumes of concentrated oxygen to a patient includes an electro-mechanical assembly having a housing with a first face, a second face and an outer surface. The oxygen concentrator also includes a first battery, a second battery, a first adsorbent container and a second adsorbent container. The first and second batteries are removably mountable to the first face and the first and second adsorbent containers are removably mountable to the second face to permit modification of the concentrated oxygen capacity and operating life of the concentrator as the patient progresses through different stages of a breathing disease. The first battery has a first battery capacity that is less than a second battery capacity of the second battery. The first adsorbent container has a first adsorbent capacity that is less than a second adsorbent capacity of the second adsorbent container. | 2020-12-03 |
20200376227 | CONCENTRATOR WITH ELECTRONIC HANDHELD REMOTE DELIVERY DEVICE - A system that enables remote adjustment of oxygen flow from an oxygen source includes a gas source device fluidly coupled to a gas source, a remote delivery device with an outlet for providing gas to a user and an inlet fluidly coupled to an outlet of the gas source device, wherein the gas source device has a control system. The control system determines a current control setting of the remote delivery device based on pneumatic feedback from the remote delivery device and modifies a pressure of gas flowing from the gas source device to the remote delivery device based on the current control setting of the remote delivery device, so that a target flow volume of supply gas associated with the current control setting is delivered to the inlet. | 2020-12-03 |
20200376228 | BREATHING ASSISTANCE APPARATUS WITH A MANIFOLD TO ADD AUXILIARY GASES TO AMBIENT GASES - The breathing assistance apparatus of the present invention includes a manifold that is provided with or retrofittable to gases supply and humidifying devices. The manifold allows gases from an oxygen concentrator to be combined with the flow through a gases supply and humidifying device, most usually air The combined output of oxygen and other breathing gases (air) is then humidified. The breathing assistance apparatus and manifold of the present invention provides a safe method to add oxygen to the input air stream of a gases supply and humidifying device and reduces the amount of accumulation of oxygen within the gases supply device, reducing fire risk should sparking occur within the device. | 2020-12-03 |
20200376229 | MIGRAINE TREATMENT PREPARATION AND METHOD - A method of ameliorating a migraine utilizing a frozen caffeinated comestible, the method constituted of: a) abutting a portion of the frozen caffeinated comestible to a user palate for at least 5 seconds; b) detaching the abutted portion from the user palate for a detachment period; and c) continuously repeating steps a-b until at least 70 milligrams of caffeine from the frozen caffeinated comestible have been consumed over a total period of at least 4 minutes. | 2020-12-03 |
20200376230 | REMOTELY CONTROLLED BILATERAL ALTERNATING TACTILE STIMULATION THERAPEUTIC METHOD AND SYSTEM - A bilateral alternating tactile stimulation therapeutic system includes an Internet web page; a first mobile device, at a first location, configured to access the Internet web page, wherein the first mobile device has a first application for transmitting audio information and pulse control information including alternating pulsation signals for uploading to the Internet web page; a second mobile device, at a second location remote from the first location, adapted to connect to the Internet web page and having a second application for receiving the audio information and the pulse control information in a streaming or live mode; a pair of pulsating devices wirelessly coupled to the second mobile device; and wherein the second mobile device is programmed to enable a subject to hear the audio information and also transmit the alternating pulsation signals to the pair of pulsating devices. | 2020-12-03 |
20200376231 | TRAUMATIC NIGHTMARE DETECTION AND INTERVENTION - The present disclosure, in one embodiment, is a computer-implemented method for the detection of and intervention in traumatic nightmares. In one embodiment, a user wears a watch wirelessly connected to a phone. The watch may include an accelerometer, gyroscope, and heartrate monitor. The application may monitor these sensors and intervene with haptic feedback if the application detects a traumatic nightmare. In one embodiment, the application may include a monitoring module that collects data from the watch's accelerometer, gyroscope, and heartrate sensors. The application may then estimate and record stress levels based on these sensors. The application may also include an intervention module that responds to high stress levels with haptic feedback that increases in intensity of previous efforts to intervene were unsuccessful. | 2020-12-03 |
20200376232 | STEERABLE CATHETER WITH PIEZOELECTRIC TRANSDUCER - A steerable medical catheter includes a tubular body having a longitudinal axis and a distal portion for insertion into a subject, a first pull wire, a second pull wire, and a piezoelectric transducer. The piezoelectric transducer includes a first electrode and a second electrode. At the distal portion of the catheter the first pull wire and the second pull wire are each mechanically coupled to the tubular body at respective first and second offset positions with respect to the longitudinal axis for imparting a curvature on the distal portion of the catheter. At the distal portion of the catheter the first pull wire is electrically connected to the first electrode of the piezoelectric transducer and the second pull wire is electrically connected to the second electrode of the piezoelectric transducer. | 2020-12-03 |
20200376233 | Line Protecting Garment - A garment for protecting a line, such as a central line or broviac line, protruding out of a body of a user, the garment having a body strap, and a pocket on an interior side of the body strap to cover and protect the line from the user. The body strap can have a slit through which the line can exit. The garment can have shoulder straps with line traps to further manage the line exiting from the body strap. | 2020-12-03 |
20200376234 | CATHETER ASSEMBLY HAVING AN INJECTION PORT AND RELATED METHODS - A catheter assembly may include a catheter adapter. A body of the catheter adapter may include a distal end, a proximal end, and a first lumen extending through the distal end and the proximal end. The catheter adapter may include a side port, which may extend outwardly from the body. The side port may include a second lumen, which may be perpendicular to the first lumen. The catheter assembly may include a catheter extending distally from the distal end of the body. The catheter assembly may include a valve disposed within the first lumen. The valve may include an outer surface that is cylindrical and may seal the first lumen from the second lumen. The catheter assembly may include a divider disposed with the second lumen. The divider may divide the second lumen into a plurality of openings and may increase a burst value of the valve. | 2020-12-03 |
20200376235 | NEEDLE CAPTURE SAFETY INTERLOCK FOR CATHETER - A catheter assembly ( | 2020-12-03 |
20200376236 | SHEATHLESS GUIDE INTRODUCER - A system for inserting a guide catheter into a relatively small vessel may include an expandable introducer configured for inserting into the vessel, expanding to dilate the vessel, and holding the vessel in an open condition. The system may also include a dilator ( | 2020-12-03 |
20200376237 | GUIDE WIRE AND MEDICAL DEVICE - A guide wire and a medical device are disclosed that have high workability, restrain erroneous puncture by a needle portion for puncture, and assure relative safety. A guide wire for guiding an elongated tubular body or dilator, and which is configured to be inserted in a living body. The guide wire includes a shaft portion, a puncture portion that is fixed to a distal portion of the shaft portion and that forms a hole in living body tissue, and a cover portion that is elastically deformable and that covers the puncture portion, in which when the cover portion is exposed from the elongated tubular body or dilator, the cover portion covers the puncture portion and the cover portion is bent. | 2020-12-03 |
20200376238 | METHOD OF USING A CATHETER ASSEMBLY - A method of using a catheter assembly for inserting in a fluid filled space in a body includes providing a main body having a first end portion and a second end portion. The first end portion is positioned within the fluid filled space. The second end portion is adjusted to extend outwardly from the fluid filled space when the first end portion is positioned within the fluid filled space. A catheter tip is connected to the second end portion of the main body. The catheter tip includes a housing having a cavity defined therein and a rotating element positioned within the fluid filled space. The rotating element is rotated within the cavity of the housing to impart movement of the first end portion of the main body within the fluid filled space. | 2020-12-03 |
20200376239 | METHODS AND SYSTEMS FOR DRAINING CEREBROSPINAL FLUID INTO THE VENOUS SYSTEM - Methods for treating hydrocephalus using a shunt, the shunt having one or more CSF intake openings in a distal portion, a valve disposed in a proximal portion of the shunt, and a lumen extending between the one or more CSF intake openings and the valve, the method comprises deploying the shunt in a body of a patient so that the distal portion of the shunt is at least partially disposed within a CP angle cistern, a body of the shunt is at least partially disposed within an IPS of the patient, and the proximal portion of the shunt is at least partially disposed within or proximate to a JV of the patient, wherein, after deployment of the shunt, CSF flows from the CP angle cistern to the JV via the shunt lumen at a flow rate in a range of 5 ml per hour to 15 ml per hour. | 2020-12-03 |
20200376240 | MEDICAL PRESSURIZATION CONTROL DEVICE - The present invention provides a medical pressurization control device, comprising an outer tube and a threaded push rod inside the outer tube. A movable caliper comprising two arms, a caliper control member connected to the movable caliper, and an operating member connected to the caliper control member are provided in the outer tube; when the operating member moves from a second position to a first position, the operating member drives the caliper control member to move to a locking position, so as to push the two arms of the movable caliper to hold the threaded push rod for locking the threaded push rod; when the operating member moves from the first position to the second position, the operating member drives the caliper control member to move to a release position, so as to push the two arms of the movable caliper to release the threaded push rod for unlocking the threaded push rod. | 2020-12-03 |
20200376241 | BUCCAL SWAB DELIVERY SYSTEM - Described herein is a drug product delivery device and method of delivering a drug on a swab. The drug product delivery device may include an applicator platform housed within a rigid housing. The applicator platform may be in the form of a plunger. The foil drug reservoir cap creates a fluid storage chamber disposed between the foil drug reservoir cap and the plunger. A series of fluidic channels carry fluid from the fluid storage chamber to an applicator. A frangible seal is attached to the plunger between the fluid storage chamber and the applicator. The frangible seal blocks a fluid from moving from the fluid storage chamber into the series of fluidic channels. Actuation of the plunger causes the frangible seal to be ruptured, which causes the fluid to exit the fluid storage chamber and enter into the fluidic channels. The fluidic channels carry the fluid to the applicator. | 2020-12-03 |
20200376242 | GASTRIC RESIDENCE SYSTEM - The present disclosure is in the field of gastric resident systems. A device for extended retention in a stomach is provided. The device includes: first, second, and third arms, the second and third arms being pivotally connected to respective ends of the first arm. The device is configured to transform between a compressed configuration and an expanded configuration. The device further includes a biasing member configured to bias the device into the expanded configuration whereby the second and third arms are configured to mechanically engage each other to retain the system in the expanded configuration. | 2020-12-03 |
20200376243 | APPLICATOR FOR WATER-SOLUBLE SHEET-SHAPED PREPARATION - To provide a means which makes it possible to reliably administer a sheet-like water-soluble preparation to skins at various sites and supply water from a back side of the sheet-like water-soluble preparation. | 2020-12-03 |
20200376244 | SYSTEMS AND METHODS FOR IN-SITU, BOTTOM-UP TISSUE GENERATION - Embodiments of the present disclosure encompass systems and methods for in-situ/in vivo, bottom-up tissue generation for wound repair, repair of tissue defects, and the like. Embodiments of the systems of the present disclosure include modular scaffolds seeded with cells (modular tissue forming units (MTFUs)) for packing a tissue defect, such that these MTFUs are able to fill the wound bed with cells of one or more needed tissue types supported by the modular scaffolding particles. | 2020-12-03 |
20200376245 | Mechanical and Electrical Intracellular Access for Cells with Tough Cell Walls - A high-throughput method, device and system technology is provided capable of unconstrained penetration into virtually any cell type. This technology is completely agnostic to the cargo type or size (DNA, RNA or protein), is ultra-robust due to use of stiff metals, and has a direct path to scalabillity. This technology will serve as an effective method of intracellular delivery. In addition, this device is reusable and capable with working with all cell types, regardless of cell stiffness, and is potentially capable of penetrating into the nucleus of a cell. An intra-cellularly delivery device with an elongated structure with an ultra-sharp tip of less than 10 nanometers enables this technology whereby intracellular access is gained with little to no observable deformation of the cell walls. This dramatically increases the likelihood of cell survival and successful delivery. | 2020-12-03 |
20200376246 | NEEDLE DISC ROLLER APPARATUS WITH PUMP - A needle disk roller apparatus having a built-in pump, includes: a drug container ( | 2020-12-03 |
20200376247 | METHOD OF PRODUCING MICRONEEDLE ARRAY - An object of the present invention is to provide a method of producing a microneedle array that enables concentration of a drug at needle tips of the microneedle array. According to the present invention, provided is a method of producing a microneedle array, including a step of filling a hydrophobic mold with a drug-containing solution to form a needle tip, and a step of filling the mold including the formed needle tip with a liquid which contains a water-soluble polymer or disaccharides to form a needle base and a sheet, in which the drug-containing solution contains 0.01 mg/mL to 5 mg/mL of a surfactant. | 2020-12-03 |
20200376248 | DC POWER SUPPLY UNIT FOR A TATTOO MACHINE AND CAPABLE OF OUTPUTTING SQUARE WAVES - A power supply unit for a tattoo machine includes a power operating unit electrically connected to a power supply device. The power operating unit is electrically connected to an operating unit. The power operating unit can output a DC power and can control a current value or a voltage value of the DC current according to operation of the operating unit. A modulating unit is electrically connected to the power operating unit and the operating unit. The modulating unit modulates the DC current according to the operation of the operating unit and outputs a square wave power or the DC power. The modulating unit can control frequency or a work cycle of the square wave power according to the operation of the operating unit. An output end of the DC power supply unit is electrically connected to the tattoo machine to output the square wave power or the DC power. | 2020-12-03 |
20200376249 | FLUSHING CATHETER - The present invention relates to a flushing catheter device, flushing catheter components, and methods for making the same. A flushing catheter includes one or more flush segments comprised of one or more flush ports along a length of catheter body. A preferred method for making a flushing catheter incorporates a retrofit including one or more flush segments. Flushing catheters may be nested within each other's lumens to form a multi-catheter system. Flush segments may enable radial fluid communication between the many lumens and annular lumens of a multi-catheter system, e.g. intraluminal fluid communication. A multi-catheter system including flushing catheters may be entirely purged of air with a single step of fluid injection. A flushing catheter may include a tapered distal end to further enhance the ease of procedure with a multi-catheter system. | 2020-12-03 |
20200376250 | THERAPEUTIC DELIVERY DEVICE - A therapeutic delivery device that provides a controlled release of high doses of a therapeutic agent in a local area, sustains the high dose controlled release with a percutaneous port for refilling the device, and is versatile for use with multiple types of therapeutic agents and/or implant systems. A rate determining/controlled release membrane is used to decrease the molecular mobility of the therapeutic compounds thereby controlling the therapeutic release profile. The therapeutic delivery device includes a body defining an internal reservoir for receiving a therapeutic agent and including a first membrane for providing a controlled release of the therapeutic agent to the surgical site, a port in fluid communication with the reservoir, a sleeve configured to encapsulate the body, and a rigid housing configured to support the body and a portion of the sleeve, the rigid housing configured to release the body and the sleeve after the body and the sleeve are anchored position relative to the surgical site. | 2020-12-03 |
20200376251 | THERAPEUTIC DELIVERY DEVICE - A therapeutic delivery device that provides a controlled release of high doses of a therapeutic agent in a local area, sustains the high dose controlled release with a percutaneous port for refilling the device, and is versatile for use with multiple types of therapeutic agents and/or implant systems. A rate determining/controlled release membrane is used to decrease the molecular mobility of the therapeutic compounds thereby controlling the therapeutic release profile. The therapeutic delivery device includes a body defining an internal reservoir for receiving a therapeutic agent and including a first membrane for providing a controlled release of the therapeutic agent to the surgical site, a port in fluid communication with the reservoir, a sleeve configured to encapsulate the body, and a rigid housing configured to support the body and a portion of the sleeve, the rigid housing configured to release the body and the sleeve after the body and the sleeve are anchored position relative to the surgical site. | 2020-12-03 |
20200376252 | NEUROLOGICAL APPARATUS COMPRISING A PERCUTANEOUS ACCESS DEVICE - Apparatus for delivering therapeutic agents to the central nervous system of a subject is described. The apparatus includes at least one intracranial catheter and a percutaneous access device. The percutaneous access device includes a body having at least one extracorporeal surface and at least one subcutaneous surface, the body defining at least one port for connection to an implanted intracranial catheter. The port is accessible from the extracorporeal surface of the device, but is provided with a seal such as a rubber bung between the lumen of the port and the extracorporeal surface. The percutaneous access device may have more than two ports and/or a flange. A method of implanting the percutaneous access device is also described. | 2020-12-03 |
20200376253 | FUNNEL-SHAPED PRESSURIZATION VALVE - The disclosure is directed to a system for maintaining hemostasis during introducing or withdrawing an interventional device. The system includes a housing. The housing includes a first end, a second end and a side wall defining a housing chamber. The system also includes a first funnel-shaped member disposed at least partially within the housing chamber. The first funnel-shaped member includes an inner portion, a middle portion and an outer portion. The inner portion of the first funnel-shaped member includes an elastic orifice, which is aligned with the through channel of the housing. The first funnel-shaped member includes an open configuration and a closed configuration. When the first funnel-shaped member is in the closed configuration, the elastic orifice is substantially closed, and when the first funnel-shaped member is in the open configuration, an interventional device is introduced through the system and the elastic orifice is open. | 2020-12-03 |
20200376254 | AUTOMATIC DISINFECTION OF A VASCULAR ACCESS DEVICE CONNECTOR - A device to couple a vascular access device to a medical device may include a body, a spring, and a housing. The body may include a distal end, a proximal end, and a lumen extending through the distal end and the proximal end. The proximal end of the body may include a connector. The housing may be coupled to a proximal end of the spring and may enclose the connector. A distal end of the spring may be coupled to the body. The housing may include a flap, which may include an antimicrobial compound. When the housing is disposed in a proximal position, the flap may cover the connector, the antimicrobial compound may contact the connector, and the spring may be uncompressed. In response to movement of the housing from the proximal position to a distal position, the spring may be compressed and the flap may open. | 2020-12-03 |
20200376255 | MINIMALLY INVASIVE IMPLANTABLE NEUROSTIMULATION SYSTEM - A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes. | 2020-12-03 |
20200376256 | MINIMALLY INVASIVE IMPLANTABLE NEUROSTIMULATION SYSTEM - A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes. | 2020-12-03 |
20200376257 | MINIMALLY INVASIVE IMPLANTABLE NEUROSTIMULATION SYSTEM - A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes. | 2020-12-03 |
20200376258 | MINIMALLY INVASIVE IMPLANTABLE NEUROSTIMULATION SYSTEM - A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes. | 2020-12-03 |
20200376259 | MINIMALLY INVASIVE IMPLANTABLE NEUROSTIMULATION SYSTEM - A medical device system for delivering a neuromodulation therapy includes a delivery tool for deploying an implantable medical device at a neuromodulation therapy site. The implantable medical device includes a housing, an electronic circuit within the housing, and an electrical lead comprising a lead body extending between a proximal end coupled to the housing and a distal end extending away from the housing and at least one electrode carried by the lead body. The delivery tool includes a first cavity for receiving the housing and a second cavity for receiving the lead. The first cavity and the second cavity are in direct communication for receiving and deploying the housing and the lead coupled to the housing concomitantly as a single unit. | 2020-12-03 |
20200376260 | DEVICES, SYSTEMS AND METHODS TO REDUCE COUPLING OF A CONDUCTOR WITHIN AN IMPLANTABLE MEDICAL LEAD - Conductors within an implantable medical lead that carry stimulation signal signals are at least partially embedded within a lead body of the medical lead over at least a portion of the length of the conductors while being surrounded by a radio frequency (RF) shield. A space between the shield and the conductors is filled by the presence of the lead body material such that body fluids that infiltrate the lead over time cannot pool in the space between the shield and the conductors. The dielectric properties of the lead body are retained and the capacitive coupling between the shield and the conductors continues to be inhibited such that current induced on the shield is inhibited from being channeled onto the conductors. Heating at the electrodes of the medical lead is prevented from becoming excessive. | 2020-12-03 |
20200376261 | METHOD AND APPARATUS FOR TREATING SLEEP APNEA - Intraoral appliances are disclosed that provide electrical stimulation to tissue in a patient's oral cavity in a manner that reduces apnea events during sleep. A representative appliance can induce a current or currents through tissue and/or anatomical structures in a manner that maintains upper airway tone and/or patency. | 2020-12-03 |
20200376262 | SYSTEMS AND METHODS FOR MAKING AND USING IMPLANTABLE ELECTRICAL/OPTICAL STIMULATION LEADS AND SYSTEMS - A stimulation lead includes light emitters disposed along the distal portion of the lead and stimulation electrodes disposed along the distal portion of the lead with a portion of the lead upon which at least one of the light emitters and at least one of the electrodes is disposed is arranged to form a coil or spiral. Another stimulation lead includes a lead body; a paddle or cuff attached to the lead body; light emitters disposed on the paddle or cuff; and stimulation electrodes disposed on the paddle or cuff. Yet another stimulation lead includes a lead body; a paddle or cuff attached to the lead body; at least one long electrode disposed on the paddle or cuff and extending at least 50% of a width or length of the paddle or cuff; and segmented stimulation electrodes disposed in at least one row or column on the paddle or cuff. | 2020-12-03 |
20200376263 | METHODS AND SYSTEMS FOR DISCRETE MEASUREMENT OF ELECTRICAL CHARACTERISTICS - An electrical stimulation system includes at least one electrical stimulation lead, each of the at least one electrical stimulation lead including a plurality of stimulation electrodes; and a processor coupled to the lead and configured to perform actions, including: directing delivery of at least one electrical pulse through at least one of the stimulation electrodes of the at least one electrical stimulation lead to tissue of a patient; and directing discrete or intermittent measurement of an electrical characteristic of the tissue using at least one of the stimulation electrodes of the at least one electrical stimulation lead during, and after, delivery of the at least one electrical pulse to the tissue of the patient. | 2020-12-03 |
20200376264 | DEVICE AND METHOD FOR PERCUTANEOUS PLACEMENT AND ANCHORING OF STIMULATING ELECTRODES IN SPINE - A system and method for anchoring an electrode that stimulates a dorsal root ganglion. The anchoring device includes a screw, collet, and locking cap. The screw is inserted into bone of the pars interarticularis and the electrode is inserted through the screw and positioned next to the dorsal root ganglion for stimulation. The screw includes a recess that is shaped to fit the collet. The collet has flexible arms. When assembled, the locking cap forces the collet into the recess thereby moving the flexible arms inward radially, impinging on the electrode and holding the electrode in place adjacent the dorsal root ganglion. | 2020-12-03 |
20200376265 | IMPLANTABLE ELECTRICAL LEADS AND ASSOCIATED DELIVERY SYSTEMS - Systems, methods, and devices to facilitate insertion of certain leads with electrode(s) into patients are described. Leads can be implanted to work in conjunction with a cardiac pacemaker or cardiac defibrillator. A lead for cardiac therapy may be inserted into an intercostal space associated with the cardiac notch of a patient. Devices for delivery may include, for example, a delivery system coupled with an electrical lead and having a handle, a component advancer and insertion tips. The handle is configured to be actuated by an operator and the component advancer is configured to advance an electrical lead into the patient. The insertion tips can be configured to close around the electrical lead within the component advancer, to push through biological tissue, and to open to enable the lead to advance into the patient. The electrical lead can also be maintained in a particular orientation during the advancement into the patient. | 2020-12-03 |
20200376267 | ELECTRICAL-STIMULATION DEVICE AND OPERATION METHOD THEREOF AND ELECTRICAL-STIMULATION SYSTEM - An electrical-stimulation device includes an electrical-stimulation signal-generating circuit, a first connection unit, a first conductive member and a second conductive member. The electrical-stimulation signal-generating circuit has a first channel for providing a first electrical-stimulation signal. The first connection unit has a plurality of first contact points and a plurality of second contact points, wherein the first contact points and the second contact points are alternately arranged. The first conductive member is connected to the first contact points. The second conductive member is connected to the second contact points. The first conductive member and the second conductive member are electrically connected to the first channel, so that the first electrical-stimulation signal is transmitted through the first contact points and the second contact points corresponding to the first channel. | 2020-12-03 |
20200376268 | EXTERNAL SPEECH PROCESSOR UNIT FOR AN AUDITORY PROSTHESIS - A cochlear implant system comprising an external component having an external speech processor unit, and an internal component. The speech processor unit monitors one or more parameters, and the speech processor unit is configured to reduce the power consumption of the cochlear implant system in the absence of one or more parameters. | 2020-12-03 |
20200376269 | ADVANCED ELECTRODE DATA ANALYSIS - A method, including applying at first and second temporal locations respective electrical currents to an electrode located in a cochlea of a recipient, obtaining first and second data indicative of electrical properties at a plurality of locations away from the electrode, the first and second data corresponding to data obtained, respectively, at the first and second temporal locations, evaluating whether or not there is an existence of a temporal change in electrical conductivity between the electrode and the plurality of locations based on the obtained data, and determining whether or not a phenomenon exists inside the cochlea based on the evaluation. | 2020-12-03 |
20200376270 | BALLOON-TYPE RETINAL STIMULATION DEVICE AND METHOD FOR MANUFACTURING SAME - A balloon type retinal stimulation device includes: a substrate unit having an insertion portion provided to be inserted into an eyeball; and a stimulation unit that is provided at one or both of one and the other surfaces of the substrate unit. The insertion portion is provided to be expandable and contractible as a fluid is injected into and discharged from an inside of the injection portion. When the insertion portion expands, one surface of the insertion portion is deformed to match a shape of the retina such that the stimulation unit is brought into close contact with the retina on which an image is formed, and the other surface of the insertion portion comes into close contact with an inner surface of the eyeball that is not a region of retina on which an image is formed, to support the insertion portion that is in contact with the region of retina on which an image is formed. | 2020-12-03 |
20200376271 | SYSTEM AND METHOD FOR PATIENT INTAKE MONITORING - A system for monitoring patient intake includes an acquisition and transmission device having an electrode configured to detect vagus nerve activity. A first internal inductive coil is configured to communicate a signal indicative of the vagus nerve activity detected by the electrode to a second external inductive coil. The system also includes a processor configured to execute instructions stored in a memory that cause the system to process the signal received by the second induction coil into data corresponding to intake of the patient and communicate the data to a server that is accessible by a clinician. | 2020-12-03 |
20200376272 | TARGETED ELECTROSTIMULATION FIELDS BASED ON FOCAL DERMATOMAL COVERAGE - Systems and methods for optimizing neuromodulation field design for pain therapy are discussed. An exemplary neuromodulation system includes an electrostimulator to stimulate target tissue to induce paresthesia, a data receiver to receive pain data including pain sites experiencing pain, and to receive patient feedback on the induced paresthesia including paresthesia sites experiencing paresthesia. The neuromodulation system includes a processor circuit configured to generate a spatial correspondence indication between the pain sites and the paresthesia sites over one or more dermatomes, determine an anodic weight and a cathodic weight for each of multiple electrode locations using the spatial correspondence indication, and generate a stimulation field definition for neuromodulation pain therapy. | 2020-12-03 |
20200376273 | ELECTROGRAPHIC OBSESSION IN HUMAN NUCLEUS ACCUMBENS - Provided herein are, inter alia, methods for detecting the anatomic structure of a nucleus accumbens in the brain of a subject. The method includes inserting an electrode into the ventral striatum of a subject; and detecting an oscillatory frequency of 30-40 Hz, thereby identifying the anatomic structure of a nucleus accumbens in the subject. The methods provided herein may include a step of delivering an electrical stimulation to ameliorate or prevent an OCD symptom from occurring. | 2020-12-03 |
20200376274 | DEVICES AND METHODS FOR CARDIAC PACING AND RESYNCHRONIZATION - Devices and methods can be used for artificial cardiac pacing and/or resynchronization. For example, this document provides improved electrodes for stimulating and sensing electrical activity of the heart, and provides pacing and resynchronization systems incorporating such electrodes. While the devices and methods provided herein are described primarily in the context of pacing, it should be understood that resynchronization can additionally or alternatively be performed in an analogous manner, and that the scope of this disclosure includes such subject matter. | 2020-12-03 |
20200376275 | CIRCUIT FOR AN IMPLANTABLE DEVICE - An integrated circuit includes: a radio-frequency (RF) to direct current (DC) rectifying circuit coupled to one or more antenna on an implantable wirelessly powered device, the rectifying circuit configured to: rectify an input RF signal received at the one or more antennas and from an external controller through electric radiative coupling; and extract DC electric power and configuration data from the input RF signal; a logic control circuit connected to the rectifying circuit and a driving circuit, the logic control circuit configured to: generate a current for the driving circuit solely using the extracted DC electrical power; in accordance with the extracted configuration data, set polarity state information for each electrode; and a driving circuit coupled to one or more electrode, the driving circuit comprising current mirrors and being configured to: steer, to each electrode and via the current mirrors, a stimulating current solely from the generated current. | 2020-12-03 |
20200376276 | NEUROSTIMULATION DEVICE WITH RECORDING PATCH - The present disclosure describes systems and methods for recording electrical activity, such as local field potentials. The system can include a recording patch that is placed inline between an implanted neurological lead and an implantable pulse stimulator. The recording patch can include recording and amplification circuitry that detects, records, and amplifies electrical activity (also referred to as signals) from a target site. The system can be used to select over which of the lead's electrodes therapeutic stimulations are delivered. | 2020-12-03 |
20200376277 | ELECTRICAL STIMULATION CONTROLLING DEVICE AND ELECTRICAL STIMULATION SYSTEM - An electrical stimulation controlling device and an electrical stimulation system are provided. In which, the electrical stimulation controlling device includes a receiving circuit and a controller coupled to the receiving circuit. The receiving circuit is configured to receive an ictal neural signal which is a signal obtained by a detector when a neural event has been occurring. The controller is further coupled to a stimulator and configured to: determine a time point to start an electrical stimulation according to the ictal neural signal after an onset of the neural event has been determined; and generate and transmit a control signal to the stimulator for providing the electrical stimulation according to the determined time point. | 2020-12-03 |
20200376278 | WAVEFORM SHAPES FOR TREATING NEUROLOGICAL DISORDERS OPTIMIZED FOR ENERGY EFFICIENCY - Systems and methods for stimulation of neurological tissue apply a stimulation waveform that is derived by a developed genetic algorithm (GA), which may be coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The waveform is optimized for energy efficiency. | 2020-12-03 |
20200376279 | Rate Responsive Pacing - Some aspects relate to systems, devices, and methods of delivering rate responsive pacing therapy. The method includes monitoring activity information related to an activity level of a patient and delivering rate responsive pacing (RRP) to the patient at a pacing rate corresponding to a RRP profile. The RRP profile may be used to generate the pacing rate based on the activity information and may be adjusted based on the monitored activity information. | 2020-12-03 |
20200376280 | HIS-BUNDLE PACING FOR ATRIOVENTRICULAR BLOCK - Systems and methods for dynamically controlling His-bundle pacing (HBP) according to an indication of a rate-related or intermittent atrioventricular (AV) block in a subject are disclosed. An exemplary medical system includes an AV conduction monitor to detect an indication of either a presence or an absence of intermittent or rate-related AV conduction disturbance using physiologic information of the subject. In the event that an intermittent or rate-related AV conduction disturbance is present, a control circuit provides a control signal to an electrostimulation circuit to deliver HBP pulses. If there is no indication of intermittent or rate-related AV conduction disturbance, or a previously detected intermittent or rate-related AV conduction disturbance has been terminated, the control circuit withholds or discontinues delivery of the HBP pulses to promote intrinsic ventricular conduction and activation. | 2020-12-03 |
20200376281 | VALVES FOR USE IN MANUFACTURING OF IMPLANTABLE MEDICAL DEVICES - A valve for use in manufacturing of implantable medical devices is insertable into a bore of the medical device during a manufacturing process. The valve is configured to remain closed while the pressure differential between an internal volume of the implantable medical device and a surrounding environment is below a particular threshold and to open when the threshold is reached, thereby allowing air or other fluids to escape from the internal volume into the surrounding environment. The valves are particularly useful during certain types of coating processes that must be performed at or near vacuum and provide an effective way to prevent ingress of coating material into the internal volume of the implantable medical device. | 2020-12-03 |
20200376282 | VENTRICULAR LEADLESS IMPLANTABLE MEDICAL DEVICE WITH DUAL CHAMBER SENSING AND METHOD FOR SAME - A computer implemented method and device for providing dual chamber sensing with a single chamber leadless implantable medical device (LIMD) are provided. The method is under control of one or more processors in the LIMD configured with specific executable instructions. The method obtains a far field (FF) cardiac activity (CA) signals for activity in a remote chamber of a heart and compares the far field CA signals to a P-wave template to identify an event of interest associated with the remote chamber. The method sets an atrial-ventricular (AV) delay based on the P-wave identified and delivers pacing pulses at a pacing site of interest to a local chamber based on the AV delay, | 2020-12-03 |
20200376283 | Method and Device for Quantification of Neuromuscular Stimulations due to RF-currents - A two-part NMS-test bench is provided with which instruments, generator voltages, and surgery modes can be evaluated with regard to neuromuscular stimulations. By separating the NMS-test bench in a first part for application of the instrument and in the second part for evaluation of the physiological effect on nerves, a measurement free of artifacts is possible. The spatial and timely separation of the RF-application from the recording of the compound action potentials makes RF-disturbances ineffective. The electrical signals gained in the instrument test chamber can be pre-processed. The recorded electrical signals emitted from the instrument can be evaluated at the nerve model an arbitrary number of times. The variance involved with the recording of compound action potentials during direct use of the instrument can thus be minimized. The separated test of the signals at the nerve model avoids thermal damage of a prepared nerve and falsification of measurement results. | 2020-12-03 |
20200376284 | IMPLANTABLE MEDICAL DEVICE FOR ARRHYTHMIA DETECTION - A computer implemented method for determining heart arrhythmias based on cardiac activity that includes under control of one or more processors of an implantable medical device (IMD) configured with specific executable instructions to obtain far field cardiac activity (CA) signals at electrodes located remote from the heart, and obtain acceleration signatures, at an accelerometer of the IMD, indicative of heart sounds generated during the cardiac beats. The IMD is also configured with specific executable instructions to declare a candidate arrhythmia based on a characteristic of at least one R-R interval from the cardiac beats, and evaluate the acceleration signatures for ventricular events (VEs) to re-assess a presence or absence of at least one R-wave from the cardiac beats and based thereon confirming or denying the candidate arrhythmia. | 2020-12-03 |
20200376285 | WEARABLE CARDIAC DEFIBRILLATOR (WCD) SYSTEM SOUNDING TO BYSTANDERS - A wearable cardiac defibrillator (“WCD”) system may include a support structure that a patient can wear, an energy storage module that can store an electrical charge, and a discharge circuit that can discharge the electrical charge through the patient so as to shock him or her, while the patient is wearing the support structure. Embodiments may actively take into account bystanders, both to protect them from an inadvertent shock, and also to enlist their help. In some embodiments, the WCD system includes a speaker system and a memory. Prompts have been saved in advance in the patient's own voice, and stored in the memory. In case of an emergency, the prompts may be played by the speaker system in the patient's own voice, and heard by a bystander. | 2020-12-03 |
20200376286 | RESCUE SERVICES ACTIVATION - A system for providing remote assistance to a caregiver during a medical event includes a computer tablet with a transmitter/receiver to communicably couple the tablet with a remote computing system associated with central caregivers, physiological sensors for collecting patient information, and a defibrillator configured to couple to the sensors and including a transmitter/receiver to communicably couple the defibrillator and tablet, and a processor to receive the patient information from the sensors, provide the patient information for display, and communicate the patient information to the tablet, the tablet being configured to generate a user alert for communications with the remote system based on a signal indicating that resuscitative treatment of the victim is being administered, the signal including the patient information received from the sensors, and the user alert including a request for a confirmation to initiate communications with the remote system, and, in response, establish communications with the remote system. | 2020-12-03 |
20200376287 | METHODS FOR INCREASING TGF-B SIGNALING - The present invention, in some embodiments thereof, is directed to a method for preserving or promoting oral tolerance in a subject in need thereof, including modulating neurons in the mid-posterior region of the insular cortex (mpIC). Further provided is a method for increasing TGF-β signaling in a subject in need thereof. | 2020-12-03 |
20200376288 | TRAUMATIC TISSUE INJURY TREATMENT SYSTEMS - A wearable article can include one or more sensors configured to sense one or more of pressure, force, acceleration, and/or tissue activity. The wearable article can also include one or more stimulators configured to generate a magnetic field and positioned to apply the magnetic field to a tissue of a user, i.e., when worn, for treating the tissue after a predetermined pressure, force, acceleration, and/or tissue activity is sensed by the one or more sensors. | 2020-12-03 |
20200376289 | IMPLANTABLE LIGHT THERAPY DEVICE - The present invention relates to an implantable light therapy device which emits visible light in a specific wavelength band for a predetermined time period according to symptoms of a disease in a state in which the implantable light therapy device is fixed to a disease site, which occurs in tissue or an organ in the human body due to inflammation to suppress or reduce inflammation inducers (for example, interleukin 1 beta (IL-1β) and interleukin 18 (IL-18)). When the inflammation inducers (for example, IL-β and IL-18) in a disease site generated due to the inflammation in the tissue or the organ of the human body are suppressed or reduced according to the present invention, inflammatory diseases (for example, Alzheimer's disease, Parkinson's disease, stroke, pancreatitis, rheumatoid arthritis) may be treated or prevented. | 2020-12-03 |