52nd week of 2009 patent applcation highlights part 50 |
Patent application number | Title | Published |
20090318645 | METHOD FOR THE PRODUCTION OF OXETANE GROUP-CONTAINING (METH)ACRYLATES - The invention relates to a process for preparing oxetane-containing (meth)acrylates. | 2009-12-24 |
20090318646 | Functionalized High Vinyl Terminated Propylene Based Oligomers - This invention relates to a functionalized co-oligomer having an Mn of 300 to 30,000 g/mol comprising 10 to 90 mol % propylene and 10 to 90 mol % of ethylene, wherein the oligomer has at least X % allyl chain ends, where: 1) X=(−0.94(mole % ethylene incorporated)+100), when 10 to 60 mole % ethylene is present in the co-oligomer, and 2) X=45, when greater than 60 and less than 70 mole % ethylene is present in the co-oligomer, and 3) X=(1.83*(mole % ethylene incorporated)−83), when 70 to 90 mole % ethylene is present in the co-oligomer. This invention also relates to a functionalized homo-oligomer, comprising propylene, wherein the oligomer has: at least 93% allyl chain ends, an Mn of about 500 to about 20,000 g/mol, an isobutyl chain end to allylic vinyl group ratio of 0.8:1 to 1.2:1.0, and less than 100 ppm aluminum. This invention also relates to a process of making functionalized homo-or co-oligomer, comprising propylene, wherein the productivity is greater than 4500 g/mmol Hf (or Zr)/hour. | 2009-12-24 |
20090318647 | Olefin Functionalization By Metathesis Reaction - This invention relates to a process to functionalize propylene co-oligomer comprising contacting an alkene metathesis catalyst with a heteroatom containing alkene, and a propylene a co-oligomer having an Mn of 300 to 30,000 g/mol comprising 10 to 90 mol % propylene and 10 to 90 mol % of ethylene, wherein the oligomer has at least X % allyl chain ends, where: 1) X=(−0.94 (mol % ethylene incorporated)+100), when 10 to 60 mol % ethylene is present in the co-oligomer, and 2) X=45, when greater than 60 and less than 70 mol % ethylene is present in the co-oligomer, and 3) X=(1.83*(mol % ethylene incorporated)−83), when 70 to 90 mol % ethylene is present in the co-oligomer. This invention also relates to a process to functionalize propylene homo-oligomer comprising contacting an alkene metathesis catalyst with a heteroatom containing alkene, and a propylene homo-oligomer, comprising propylene, wherein the oligomer has: at least 93% allyl chain ends, an Mn of about 500 to about 20,000 g/mol, an isobutyl chain end to allylic vinyl group ratio of 0.8:1 to 1.2:1.0, and less than 100 ppm aluminum. | 2009-12-24 |
20090318648 | MEDIA-RESISTANT COATING RESINS - The invention relates to compositions comprising glycerol mono(meth)acrylate and hydroxyethyl methacrylate, including those with addition of further monomers, free-radically polymerized and subsequently crosslinked with isocyanates, to a process for preparing them and to their use as film-forming resins with particular media resistance. | 2009-12-24 |
20090318649 | Styrene-Maleic Anhydride Copolymers for Bioapplications and Their Preparation - The present invention discloses styrene-maleic anhydride copolymers preparations using solventless techniques. The solventless method resulted in reduced amounts of residues, such as unreacted styrene and/or maleic anhydride monomers, which makes the copolymers particularly suitable for bioapplications. | 2009-12-24 |
20090318650 | NOVEL FLUORINE-CONTAINING POLYMER AND METHOD OF PRODUCING FLUORINE-CONTAINING POLYMER - A method of producing a fluorine-containing polymer, containing conducting an addition polymerization of a fluorine-containing compound having 2 or more terminal fluorine-containing vinyl groups each directly bonded to an oxygen atom per molecule, and a compound having 2 or more groups represented by —XH, where X represents an oxygen atom or a sulfur atom; and a fluorine-containing polymer comprising a repeating unit represented by formula (i): | 2009-12-24 |
20090318651 | HETEROCYCLIC COMPOUND AND HETEROCYCLIC POLYMERS - The present invention provides a heterocyclic compound of the following general formula (I): | 2009-12-24 |
20090318652 | NOVEL COMPOUND, POLYMER, AND RESIN COMPOSITION - A radiation-sensitive resin composition which has high transparency to radiation, excelling in basic properties as a resist such as sensitivity, resolution, and pattern shape, and, in particular, exhibiting high resolution performance, excellent DOF and LER, and high resistance to a liquid medium used in liquid immersion lithography is provided. Also provided are a polymer which can be used in the composition, a novel compound useful for synthesizing the polymer, and a method of producing the composition. A radiation-sensitive resin composition having an excellent resistance to a liquid medium can be obtained by using the novel compound shown by the following formula (1), | 2009-12-24 |
20090318653 | COMPOSITION FOR MANUFACTURING A CARBOXYLIC GROUP-CONTAINING POLYMER AND A POLYMER MANUFACTURED BY USING THE SAME - The present invention relates to a composition for manufacturing a carboxylic group-containing polymer and a carboxylic group-containing polymer manufactured by using the same. More particularly, the present invention relates to a composition for manufacturing a carboxylic group-containing polymer comprising an allyl monomer having a long chain of a hydrophilic part containing alkylene oxide and a side chain of a hydrophobic part containing fatty acid ester as a dispersion promoter; a vinyl group-containing unsaturated carboxylic acid; a vinyl group-containing crosslinking agent; and a radical polymerization initiator, and a carboxylic group-containing polymer manufactured by using the same wherein the polymer can be dispersed in water without stirring, its dispersion solution has low viscosity, and its neutralized viscous solution obtained by alkali neutralization has high viscosity and transparency. Therefore, the carboxylic group-containing polymer of the present invention can be effectively used in the fields of a thickener and a dispersion stabilizer for an emulsion, a suspension and the like. | 2009-12-24 |
20090318654 | SINTERING ULTRAHIGH MOLECULAR WEIGHT POLYETHYLENE - Ultrahigh molecular weight polyethylene compositions of highly beneficial sintering characteristics are disclosed and methods for making and processing time. Additionally, products comprising these compositions are described. | 2009-12-24 |
20090318655 | POLYCARBOSILANE AND METHOD OF PRODUCING THE SAME - Provided are polycarbosilane and a method of producing the same. The polycarbosilane contains an allyl group, and thus can be cured by UV absorption when not exposed to the air. | 2009-12-24 |
20090318656 | Polyetheramine Macromonomers Comprising Two Neighboring Hydroxyl Groups And Their Use For Producing Polyurethanes - The object of the invention are compounds of the formula (2) wherein R | 2009-12-24 |
20090318657 | Sealing gasket for closure and process for production of closure using the same - A sealing gasket for closure, made of a polyurethane elastomer obtained by reacting the following (A), (B) and (C):
| 2009-12-24 |
20090318658 | BAKED RESIN PRODUCT AND ELECTRONIC DEVICE COMPRISING SAME - The present invention provides a baked resin product that exhibits an excellent heat resistance and an electronic device that incorporates this baked resin product. The present invention provides a baked resin product obtained by baking a resin composition that contains a main chain-type aromatic benzoxazine structure, wherein the baked resin product has a peak measured by | 2009-12-24 |
20090318659 | BIOCIDAL POLYMER AND PROCESS FOR PREPARING THE SAME - Disclosed herein is a biocidal polymer including at least one repeating unit of formula (A): | 2009-12-24 |
20090318660 | CROSSLINKABLE ARAMID COPOLYMERS - The invention pertains to an aramid copolymer composition comprising an aramid copolymer having at least one arylene carboxylic acid moiety and at least one hydroxyarylene moiety, or comprising an aramid copolymer having at least one arylene carboxylic acid moiety or having at least one hydroxyarylene moiety, and a crosslinker agent. The invention further relates to crosslinked copolymers derived thereof and shaped articles comprising said crosslinked copolymers. | 2009-12-24 |
20090318661 | A BIOCOMPATIBLE, NON-BIODEGRADABLE, NON-TOXIC POLYMER USEFUL FOR NANOPARTICLE PHARMACEUTICAL COMPOSITIONS - The invention relates to a biocompatible, non-biodegradable, and non-toxic polymer of formula (I), comprising of three monomeric units, selected from 1-Vinylpyrrolidone (VP), N-Isopropylacrylamide (NIPAM), and ester of Maleic anhydride and Polyethylene glycol (MPEG), cross-linked with a bi-functional vinyl derivative, of high purity and substantially free of respective toxic monomeric contaminants, and a process for preparation thereof. The invention further relates to nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds comprising the polymer of the invention, which are safe, less-toxic and convenient for bedside administration to patients in need thereof. Furthermore, the invention relates to a highly selective method for preparation of nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds. | 2009-12-24 |
20090318662 | Hydrazine storage resin - A hydrazine-fixing group such as a ketone group, a formyl group, a chlormethyl group or an amide group, which is capable of releasably fixing hydrazine, is introduced into a side chain of a synthetic resin, and hydrazine is fixed to the hydrazine-fixing group. Since a hydrazine storage resin of the present invention has a hydrazine-releasable group capable of releasing hydrazine, it is able to store hydrazine stably. In addition, hydrazine can be supplied by releasing hydrazine from the hydrazine-releasable group. Consequently, the hydrazine storage resin can be widely used in various industrial fields requiring supply of hydrazine. | 2009-12-24 |
20090318663 | Polymerizable Spherical Transition Metal Complex, Spherical Transition Metal Complex, and Production Method Thereof - A polymerizable spherical transition metal complex is provided which has a hollow shell which is formed from transition metal atoms and bidentate organic ligands, the bidentate organic ligands having a substituent having a polymerizable group moiety at an end thereof, and the substituents being oriented towards the interior of the hollow shell. A spherical transition metal complex in which, in the hollow shell of the polymerizable spherical transition metal complex, the polymerizable groups are polymerized, and a production method thereof are also provided. The polymerizable spherical transition metal complex which is a spherical transition metal complex having a hollow shell, is characterized in that the hollow shell is formed from a transition metal atoms (wherein a represents an integer of 6 to 60), and 2a bidentate organic ligands, the bidentate organic ligands have a substituent having at least one or more polymerizable group moieties at an end thereof, and the substituents are oriented towards an interior of the hollow shell. The spherical transition metal complex is characterized in that the polymerizable groups are polymerized in the hollow shell of the polymerizable spherical transition metal complex. The production method thereof is also provided. | 2009-12-24 |
20090318664 | LOW PROFILE LUBRICANT WITH CYCLOPHOSPHAZENE RING ATTACHED - A compound comprising a backbone with a perfluoropolyether chain. The compound also has one or more cyclophosphazene rings attached to or incorporated into the backbone. The compound further includes at least two functional groups attached to the backbone, attached to the one or more cyclophosphazene rings, or a combination thereof. | 2009-12-24 |
20090318665 | PHARMACEUTICAL FORMULATIONS - Good bioavailability of desmopressin can be obtained by means of an orodispersible pharmaceutical dosage form. Preferred dosage forms comprise desmopressin and an open matrix network which is an inert water-soluble or water-dispersible carrier material. Desmopressin formulated in this way is useful for voiding postponement, or the treatment or prevention of incontinence, primary noctural enuresis (PNE), nocturia or central diabetes insipidus. Peptides other than desmopressin can also be formulated in this way. | 2009-12-24 |
20090318666 | Synthetic Dog/Human Chimeric C-C Chemokine Receptor 2B - Disclosed herein are polynucleotides encoding a chimeric C—C chemokine receptor 2B, the encoded polypeptides thereof and methods of making and using said polynucleotides and polypeptides. | 2009-12-24 |
20090318667 | Peptoid compositions and methods of using the same - Novel peptoids are disclosed that have a formula represented by the following formulae Ia and Ib: | 2009-12-24 |
20090318668 | Water-Soluble CC-1065 Analogs and Their Conjugates - This invention relates to novel analogs of the DNA-binding alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and their conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor. | 2009-12-24 |
20090318669 | Novel Isodipeptide - An isodipeptide of the following formula (1) which is a useful synthetic unit for the effective synthetic method for a polypeptide and the like: | 2009-12-24 |
20090318670 | Separation of Proteins from Grasses Integrated with Ammonia Fiber Explosion (AFEX) Pretreatment and Cellulose Hydrolysis - A process for extracting an aqueous ammonium hydroxide solution from a plant biomass after an Ammonia Fiber Explosion (AFEX) process step, is described. The proteins can be separated before or after a hydrolysis of sugar precursors (carbohydrates) from the biomass to produce sugars for fermentation to produce ethanol. The proteins are useful as animal feeds because of their amino acid food values. | 2009-12-24 |
20090318671 | Novel canola protein isolate - A novel canola protein isolate consisting predominantly of 2S canola protein and having equal to better solubility properties and improved clarity properties, has an increased proportion of 2S canola protein and a decreased proportion of 7S canola protein. The novel canola protein isolate is formed by heat treatment or isoelectric precipitation of aqueous supernatant from canola protein micelle formation and precipitation, to effect precipitation of 7S protein which is sedimented and removed. Alternatively, the novel canola protein isolate may be derived from a selective membrane procedure in which an aqueous canola protein solution containing 12S, 7S and 2S canola proteins is subjected to a first selective membrane technique to retain 12S and 7S canola proteins in a retentate, which is dried to provide a canola protein isolate consisting predominantly of 7S canola protein, and to permit 2S canola protein to pass through the membrane. The permeate is subjected to a second selective membrane technique to retain 2S canola protein and to permit low molecular weight contaminants to pass through the membrane, and the retentate from the latter membrane technique is dried. | 2009-12-24 |
20090318672 | ANTIBODIES TO PRO352 - The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. | 2009-12-24 |
20090318673 | METHOD OF CHANGING FLUORESCENCE WAVELENGTH OF FLUORESCENT PROTEIN - The present invention provides: a method of changing the fluorescence wavelength of a GFP-like fluorescent protein from copepod while maintaining recombinant expression efficiency, which comprises identifying a structural factor for determining the fluorescence wavelength thereof in the three-dimensional structure of the protein and modifying amino acid residues associated with the structural factor; and a modified fluorescent protein obtained by applying said method. For example, with regard to a GFP-like fluorescent protein from | 2009-12-24 |
20090318674 | PROCESS FOR PURIFICATION OF ANTIBODIES - The disclosed embodiments are directed to methods and compositions for purification of proteins, in particular, to methods and compositions for an antibody purification process that includes aggregate removal and the use of solubility enhancing additives such as zwitterion-containing compositions to enhance antibody solubility and avoid aggregate formation or occlusion during ion exchange chromatography, yielding a high-purity protein product substantially free of aggregates. | 2009-12-24 |
20090318675 | NOVEL GEM-DIFLUORINATED C-GLYCOSIDE COMPOUNDS DERIVED FROM PODOPHYLLOTOXIN, THEIR PREPARATION AND THEIR APPLICATIONS - The invention relates to a gem-difluoride glycoconjugated compound with formula (I): where R represents II or a benzyl, acetyl, benzoyl alkyl group, R | 2009-12-24 |
20090318676 | OLIGONUCLEOTIDES COMPRISING A NON-PHOSPHATE BACKBONE LINKAGE - One aspect of the present invention relates to a ribonucleoside substituted with a phosphonamidite group at the 3′-position. In certain embodiments, the phosphonamidite is an alkyl phosphonamidite. Another aspect of the present invention relates to a double-stranded oligonucleotide comprising at least one non-phosphate linkage. Representative non-phosphate linkages include phosphonate, hydroxylamine, hydroxylhydrazinyl, amide, and carbamate linkages. In certain embodiments, the non-phosphate linkage is a phosphonate linkage. In certain embodiments, a non-phosphate linkage occurs in only one strand. In certain embodiments, a non-phosphate linkage occurs in both strands. In certain embodiments, a ligand is bound to one of the oligonucleotide strands comprising the double-stranded oligonucleotide. In certain embodiments, a ligand is bound to both of the oligonucleotide strands comprising the double-stranded oligonucleotide. In certain embodiments, the oligonucleotide strands comprise at least one modified sugar moiety. Another aspect of the present invention relates to a single-stranded oligonucleotide comprising at least one non-phosphate linkage. Representative non-phosphate linkages include phosphonate, hydroxylamine, hydroxylhydrazinyl, amide, and carbamate linkages. In certain embodiments, the non-phosphate linkage is a phosphonate linkage. In certain embodiments, a ligand is bound to the oligonucleotide strand. In certain embodiments, the oligonucleotide comprises at least one modified sugar moiety. | 2009-12-24 |
20090318677 | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof - The present invention relates generally to the control of body weight of animals including mammals and humans, and more particularly to materials identified herein as modulators of weight, and to the diagnostic and therapeutic uses to which such modulators may be put. In its broadest aspect, the present invention relates to the elucidation and discovery of nucleotide sequences, and proteins putatively expressed by such nucleotides or degenerate variations thereof, that demonstrate the ability to participate in the control of mammalian body weight. The nucleotide sequences in object represent the genes corresponding to the murine and human ob gene, that have been postulated to play a critical role in the regulation of body weight and adiposity. Preliminary data, presented herein, suggests that the polypeptide product of the gene in question functions as a hormone. The present invention further provides nucleic acid molecules for use as molecular probes, or as primers for polymerase chain reaction (PCR) amplification, i.e., synthetic or natural oligonucleotides. In further aspects, the present invention provides a cloning vector, which comprises the nucleic acids of the invention; and a bacterial, insect, or a mammalian expression vector, which comprises the nucleic acid molecules of the invention, operatively associated with an expression control sequence. Accordingly, the invention further relates to a bacterial cell or a mammalian transfected or transformed with an appropriate expression vector, and correspondingly, to the use of the above mentioned constructs in the preparation of the modulators of the invention. Also provided are antibodies to the ob polypeptide. Moreover, a method for modulating body weight of a mammal is provided. In specific examples, genes encoding two isoforms of both the murine and human ob polypeptides are provided. | 2009-12-24 |
20090318678 | Stable C-Glycoside Sugar and C-Glycoconjugate Mimetics, Method for preparing same and uses Thereof in Particular in Cosmetics and Drugs - The invention concerns a C-glycoside compound of formula (I); wherein: n is equal to 1 or 2; Y represents H or halogen; X is an alkyl chain bearing at least one amino, amide, acid, ester, carbonyl, alcohol, aryl function or a carbonyl, ester amide, amino, alcohol group; the R's, identical or different, represent a OH or OR′ group where R′ is an alkyl, benzyl, benzoyl, acetyl, pivaloyl, trialkylsilyl, tertiobutyldiphenylsilyl group or one or more sugars; R1 represents OR′, NR″R″′, N3, or a phthalamide with R″ and R″′, identical or different, represent H or an alkyl, aryl, benzyl, benzoyl, acetyl, alkoxycarbonyl, allyloxycarbonyl, benzyloxycarbonyl group; R2 represents H or halogen or a OH, OR, NR″R″′ or N3 group, as well as derivatives thereof in physiologically or pharmaceutically acceptable base, mineral or organic acid-addition salt, hydrate or solvate form. The invention is useful for preparing C-glycoside compounds or C-glycoconjugates applicable in particular in cosmetology, medical imagery, immunology for treating cancer, diabetes, hypertension. | 2009-12-24 |
20090318679 | APPARATUS AND METHOD FOR HYDROLYSIS OF CELLULOSIC MATERIAL IN A TWO-STEP PROCESS - A system and method for extracting pentose from a slurry of cellulosic material comprising cellulose, water, and optionally acid in a two-stage process. | 2009-12-24 |
20090318680 | Boron-Containing Porphyrin Compounds and Their Uses - Boron-containing porphyrin compounds are disclosed that may be used for boron neutron capture therapy of tumors, radiotherapy of tumors, and photodynamic therapy of tumors. | 2009-12-24 |
20090318681 | METAL COMPLEX, AND USE THEREOF - Provided is a metal complex represented by the following formula (A-1) or (B-1) as a metal complex useful for a redox reaction catalyst or some other article that is excellent in heat resistance and acid resistance: | 2009-12-24 |
20090318682 | Process for the synthesis of 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid - Process for the synthesis of the compound of formula (I): | 2009-12-24 |
20090318683 | METHOD FOR PREPARING A MIXED SOLVATE OF OLANZAPINE - An improved method is provided for preparing a mixed solvate of olanzapine/water/tetrahydrofuran in a proportion of 1:1:1/2. Said improvement is characterised in that said mixed solvate is basically prepared by means of methylation of the N-desmethylolanzapine with dimethyl sulphate, using tetrahydrofuran and water as solvents. | 2009-12-24 |
20090318684 | ROCK INHIBITORS AND USES THEREOF - The subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are compounds that inhibit Rho-protein associated kinase function. Compounds of the invention include piperazinyl pyridines, piperazinylmethyl pyridines, piperazinyl ureas and carbamates, piperazinyl pyridines and quinoilines (including isoquinliones) as well as piperazinyl (including piperazinylmethyl) pyridines and quinolines (including isoquinolines). Compounds of the invention disrupt Rho-kinase activation and function and significantly inhibit tumor cell growth and induce tumor cell death. | 2009-12-24 |
20090318685 | METHOD FOR PRODUCING 3,4-DIHYDRO-1,2,3-OXATHIAZIN-4-ONE-2,2-DIOXIDE COMPOUND OR SALT THEREOF - A high quality 3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide compound or a salt thereof is obtained easily and efficiently. | 2009-12-24 |
20090318686 | METHOD FOR PRODUCING POTASSIUM SALT OF 3,4-DIHYDRO-1,2,3-OXATHIAZIN-4-ONE-2,2-DIOXIDE COMPOUND - A method for producing a high quality potassium salt of 3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide compound easily and efficiently is provided. | 2009-12-24 |
20090318687 | Methods of Treating or Preventing Autoimmune Diseases With 2,4-Pyrimidinediamine Compounds - The present invention provides methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds, as well as methods of treating, preventing or ameliorating symptoms associated with such diseases. Specific examples of autoimmune diseases that can be treated or prevented with the compounds include rheumatoid arthritis and/or its associated symptoms, systemic lups erythematosis and/or its associated symptoms and multiple sclerosis and/or its associated symptoms. | 2009-12-24 |
20090318688 | METHOD FOR PREPARING PHENYLALANINE DERIVATIVES HAVING QUINAZOLINE-DIONE SKELETON AND INTERMEDIATES FOR USE IN THE PREPARATION OF DERIVATIVES - A method for preparing a phenylalanine derivative having a quinazoline-dione ring represented by the following formula (1) or a pharmaceutically acceptable salt thereof, comprising the following steps (a), (b) and (c): | 2009-12-24 |
20090318689 | Processes To Make Apoptosis Promoters - Processes to make compounds, including N-acylsulfonamide apoptosis promoters are disclosed. | 2009-12-24 |
20090318690 | Benzisoxazole Compound - Disclosed is a compound represented by the general formula (I) or a salt thereof: | 2009-12-24 |
20090318691 | Novel Aromatic AZA Heterocycles, Method of Production and Use of the Material in Organic Electronics - An electron transport material based on fused aromatic electron-deficient compounds. The accumulation of aromatic rings with an electron deficiency allows free-radical anions to be stabilized very efficiently in these systems. | 2009-12-24 |
20090318692 | PROCESS OF MAKING IMATINIB - The present invention provides a process of coupling the compound (2) and compound (3) in the presence of a coupling agent, yielding imatinib of formula (1). | 2009-12-24 |
20090318693 | LIGANDS FOR ESTROGEN RELATED RECEPTORS AND METHODS FOR SYNTHESIS OF SAID LIGANDS - Estrogen-Related Receptor (ERR) modulating compounds and methods for synthesis of said compounds are described. | 2009-12-24 |
20090318694 | Cross-Linked Amine Compounds and Agents for Pest Control - Cyclic amine compounds represented by formula (1) | 2009-12-24 |
20090318695 | PROCESSES FOR THE PREPARATION OF VARENICLINE AND INTERMEDIATES THEREOF - The invention provides an improved process for the preparation and purification of Varenicline and intermediates for the preparation of Varenicline. | 2009-12-24 |
20090318696 | Synthesis and use of MSE-framework type molecular sieves - A method of synthesizing a crystalline molecular sieve having an MSE framework type comprises crystallizing a reaction mixture comprising a source of water, a source of an oxide of a tetravalent element, Y, selected from at least one of silicon, tin, titanium, vanadium and germanium, a source of an alkali or alkaline earth metal, M, and a source of organic cations, Q, having the following general structure: | 2009-12-24 |
20090318697 | PROCESS FOR PREPARING A PIPERAZINE DERIVATIVE - Disclosed is a process for preparing purified ranolazine of formula (I), which is indicated for the chronic treatment of angina, comprising reacting 1-[(2,6-dimethylphenyl)aminocarbonyl]piperazine with 1-phenoxy-2,3-epoxypropane in an inert solvent followed by precipitating the ranolazine. | 2009-12-24 |
20090318698 | Use of Metal Complexes as Emitter in an Organic Light-Emitting Component and such a Component - A HEMT device including a GaN channel structure including a very thin (Al, In, Ga)N subchannel layer ( | 2009-12-24 |
20090318699 | Methods of synthesis of morphinans - The disclosure describes morphinan compounds and methods for their synthesis. Preferred methods according to the disclosure allow for large-scale preparation of diastereomerically enriched morphinans. Preferred methods according to the disclosure may also allow for the preparation of diastereomerically enriched morphinans using less time, and/or using fewer reaction steps, and/or providing better yield than previously used methods for preparing morphinans. The methods disclosed herein find utility in synthetic organic chemistry as well as medicinal chemistry. | 2009-12-24 |
20090318700 | PROCESS FOR PREPARING PRADOFLOXACIN - The invention relates to an improved process for preparing pradofloxacin, in which the substituent in the 7 position is introduced by nucleophilic substitution in an N-methylpyrrolidone-ethanol solvent mixture. | 2009-12-24 |
20090318701 | METHOD PREPARATION CLOPIDOGREL AND INTERMEDIATES USED THEREIN - Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt. | 2009-12-24 |
20090318702 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND - The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, the present invention provides, for example, compounds represented by the formulas (6), (7-1), (7-2) and (8): | 2009-12-24 |
20090318703 | CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL AGENT COMPRISING THE SAME AS ACTIVE INGREDIENT - A carboxylic acid derivative of formula (I): | 2009-12-24 |
20090318704 | Processes for the Preparation of N-(2-Acetyl-4,6-Dimethylphenyl)-3--2-Thiophenecarboxamide - Provided are processes for the preparation of N-(2-Acetyl-4,6-dimethylphenyl)-3-{[(3,4-dimethyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxamide, a compound useful for the treatment of endothelin-mediated disorders. | 2009-12-24 |
20090318705 | METHODS OF PREPARING IMIDAZOLE-BASED BICYCLIC COMPOUNDS - Methods of preparing compounds of formula I are disclosed: | 2009-12-24 |
20090318706 | Process for the Preparation of Candesartan Cilexetil - The present invention provides an improved synthesis for the manufacture of candesartan and pharmaceutically acceptable salts and esters thereof as active ingredients of a medicament for the treatment of hypertension and related diseases and conditions which comprises the removal of the tetrazolyl protecting group in an organic solvent, and in the presence of a Lewis acid. | 2009-12-24 |
20090318707 | NOVEL MALEIMIDE DERIVATIVE - A compound represented by the following general formula (I): | 2009-12-24 |
20090318708 | 2-Oxo-1-Pyrrolidine Derivatives, Processes For Preparing Them And Their Uses - The present invention relates to optically enriched or substantially optically pure 4-substituted-pyrrolidin-2-ones of formula (III), and their uses for the synthesis of 2-oxo-pyrrolidin-1-yl derivatives. | 2009-12-24 |
20090318709 | PROCESS FOR THE SYNTHESIS OF N-[3-[(2-METHOXYPHENYL] SULFANYL] -2-METHYLPROPYL] -3,4-DIHYDRO-2H-1,5-BENZOXATHIEPIN-3-AMINE. - The invention relates to a new process for the preparation of N-[3-[(2-methoxyphenyl)sulfanyl]-2-methylpropyl]-3,4-dihydro-2H-1,5-benzoxathiepin-3-amine. | 2009-12-24 |
20090318710 | PROCESS FOR THE PURIFICATION OF THIOPHENES - The invention relates to a process for the purification of thiophenes by means of precipitation. The purified thiophenes are liquid at room temperature, have a purity of at least 99.50 wt. %, and are represented by the following general formula (I), | 2009-12-24 |
20090318711 | Non-Covalent Inhibitors of AmpC -Lactamase - β-lactamases are the most widespread resistance mechanism to β-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced. Unfortunately, these inhibitors are also β-lactams, and resistance to them has developed rapidly. Consequently, the present invention provides a novel structure-based approach to inhibitors of these enzymes. | 2009-12-24 |
20090318712 | CATALYST SYSTEM AND METHOD FOR PRODUCING CARBOXYLIC ACIDS AND/OR CARBOXYLIC ACID ANHYDRIDES - Catalyst systems for preparing carboxylic acids and/or anhydrides, the catalyst system comprising a reaction zone and a layered catalyst, the reaction zone comprises a gas inlet region and a gas outlet region, the layered catalyst comprises an active composition and one or more middle layers, one or more first layers disposed on a side of the one or more middle layers toward the gas inlet region, and one or more second layers on a side of the one or more middle layers toward the gas outlet region, wherein the active composition content of one or more of the middle catalyst layers, based on total mass of the layered catalyst, is lower than the active composition content of the one or more first catalyst layers and is lower than one or more second catalyst layers; and processes for gas phase oxidation employing a layered catalyst of the present invention. | 2009-12-24 |
20090318713 | PROCESS FOR MANUFACTURING A CYCLIC DIESTER OF AN A-HYDROXY ACID - Process for manufacturing a cyclic diester of an α-hydroxy acid comprising the following steps:
| 2009-12-24 |
20090318714 | ORGANIC COMPOUNDS - The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula VI, | 2009-12-24 |
20090318715 | Method for the Production of D,L-2-Hydroxy-4-Alkylthio Butyric Acid - The present invention relates to a process for preparing compounds of the formula (I) | 2009-12-24 |
20090318716 | METHOD FOR PURIFYING HYDROXYCARBOXYLIC ACID, METHOD FOR PRODUCING CYCLIC ESTER, AND METHOD FOR PRODUCING POLYHYDROXYCARBOXYLIC ACID - A process for purification of a hydroxycarboxylic acid by distillation, comprising: distilling a hydroxycarboxylic acid solution containing a high-boiling point hydroxy compound comprising at least one species selected from the group consisting of alcohols and phenols having a higher boiling point than the hydroxycarboxylic acid. As a result, a hydroxycarboxylic acid suitable as a starting material for production of a polyhydroxycarboxylic acid can be obtained. The purified hydroxycarboxylic acid is further polycondensed to provide a hydroxycarboxylic acid oligomer, which is de-polymerized to provide a cyclic ester comprising a dimer of the hydroxycarboxylic acid, and the cyclic ester is converted into a polyhydroxycarboxylic acid by ring-opening polymerization thereof. | 2009-12-24 |
20090318717 | Novel hybride materials and related methods and devices - The invention provides devices and methods for end and side derivatization of carbon nanotubes. Also facile methods to attach moieties and nanoparticles on the side walls and both ends are described. The invention provides hybide materials for analytical, and optoelectronic purposes as well as materials applications. Materials have improved properties in the areas of tensile, electrical and thermal conductivity. | 2009-12-24 |
20090318718 | PROCESS FOR PRODUCTION OF GLYCIDOL - The present invention relates to a process for producing glycidol from glycerol carbonate as a raw material with a high yield. The process for producing glycidol according to the present invention includes the steps of (1) reducing a content of a salt having a weak acidity in glycerol carbonate to 1500 ppm by mass or less; and (2) obtaining the glycidol from the glycerol carbonate. | 2009-12-24 |
20090318719 | METHOD OF PREPARATION AND ISOLATION OF BETULIN DIACETATE FROM BIRCH BARK FROM PAPER MILLS AND ITS OPTIONAL PROCESSING TO BETULIN - The invention relates to a method of preparation and isolation of betulin diacetate from birch bark from paper mills and its optional processing to betulin, wherein the birch bark is ground, mixed with two- to twenty-fold excess volume of water and is stirred so that all birch bark is dipped, then the fraction of the birch bark which floats on the surface is collected, said collected fraction is dried at the temperature in the range of from 50 to 85° C. and the betulin contained in the dried birch bark is then subjected to an acetylation reaction, after the acetylation the birch bark is dried at the temperature of from 50 to 100° C. and the formed betulin diacetate is then isolated from the birch bark by supercritical extraction of the birch bark with carbon dioxide at the pressure of 28-35 MPa and the temperature of from 50 to 100° C. and subsequently, the supercritical extract is recrystallized for direct use or for further processing. The further processing can be basic hydrolysis of the re-crystallized betulin diacetate to betulin. | 2009-12-24 |
20090318720 | Process for selectively synthesising 3 alpha-hydroxychlormadinone acetate - The invention relates to a process for synthesising 3α-hydroxychlormadinone acetate. | 2009-12-24 |
20090318721 | Process for the preparation of 7alpha-alkylated 19-norsteroids - Processes useful in the preparation of pharmaceutical compounds such as fulvestrant and processes for the preparation of fulvestrant. | 2009-12-24 |
20090318722 | PROCESS FOR PREPARATION OF PARICALCITOL INTERMEDIATES - The present invention relates to a compound and a novel process for the preparation of Paricalcitol intermediates. | 2009-12-24 |
20090318723 | Novel Ru-Containing Polyoxotungstates and Process for Their Preparation - The invention relates to polyoxometalates represented by the formula (A | 2009-12-24 |
20090318724 | HYDROSILYLATION METHOD - Compounds containing carbon-carbon double bonds and/or carbon-carbon triple bonds are hydrosilylated with linear organopolysiloxanes having diorganosiloxy units and Si—H groups, produced by reacting diorganodichlorosilanes and monochlorosilanes and optionally dichlorosilanes with water in a first step, where at least one of the monochlorosilanes or dichlorosilanes contain Si—H groups to give a partial hydrolysate and gaseous hydrogen chloride, and in a second step, treating the partial hydrolysate with water to remove SiCl groups still present to form hydrochloric acid, and producing a hydrolysate containing the organopolysiloxanes. | 2009-12-24 |
20090318725 | HIGH REFRACTIVE INDEX MATERIAL - Disclosed is a high refractive index material having a high refractive index, which enables the formation of a waveguide by a simpler method. Also disclosed are a high refractive index member made from the high refractive index material, and an image sensor. The high refractive index material contains a resin (A) having a structural unit represented by the following general formula (a-1). | 2009-12-24 |
20090318726 | NEW SILYLSUBSTITUTED 1,2-ALKYNES AND SYNTHESIS OF SILYLSUBSTITUTED 1,2-ALKYNES - New silylsubstituted 1,2-alkynes of the general formula 1 and a new way of synthesis of new and already known silylsubstituted 1,2-alkynes of the general formula 1. The unknown silylsubstituted 1,2-alkynes of general formula 1, in which R | 2009-12-24 |
20090318727 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS - In a process for the preparation of ring compounds via a combinatorial synthesis, the reaction procedure is based on a Suzuki coupling, subsequent halo-demetallation and finally a further Suzuki coupling. The Suzuki couplings are each carried out with a boronic acid or a boronic acid ester. The reaction procedure uses provides novel ring compounds and uses novel synthesis units used for this purpose. The novel ring compounds are suitable for use as constituents in liquid-crystalline mixtures. | 2009-12-24 |
20090318728 | PROCESSES FOR PREPARING PRODRUGS OF GABAPENTIN AND INTERMEDIATES THEREOF - Gabapentin prodrugs and intermediates thereof are described. | 2009-12-24 |
20090318729 | IMMOBILIZED LEWIS ACID CATALYSTS COATED WITH IONIC LIQUIDS AND USE THEREOF - The invention provides a novel immobilized Lewis acid catalyst which exhibits high catalytic activity in an aqueous solution and which permits recovery and reuse or long-term continuous use. The invention relates to an immobilized Lewis acid catalyst comprising a solid substance and a Lewis acid supported on the surface of the solid substance by chemical bonding, wherein the surface of the solid substance and the peripheries of the Lewis acid are coated with an ionic liquid, more specifically, an immobilized Lewis acid catalyst comprising a solid substance such as silica gel or an organic polymer and a Lewis acid stable even in water which is supported on the surface of the solid substance by chemical bonding, wherein the surface of the solid substance and the peripheries of the Lewis acid are completely or partially coated with a hydrophobic ionic liquid; a process for the production of the catalyst; use thereof; and a process for the preparation of compounds with the catalyst. | 2009-12-24 |
20090318730 | Method of Separating and Collecting Optically Active Amino Acid Amide - [Problems] To provide a method for efficiently separating and collecting an optically active amino acid amide and an optically active amino acid which are highly important substances as intermediates in the production of various industrial chemicals, agricultural chemicals, and pharmaceuticals, from an aqueous solution containing the optically active amino acid amide and the optically active amino acid. | 2009-12-24 |
20090318731 | METHOD FOR PRODUCING 3-(2,2,2-TRIMETHYL-HYDRAZINIUM) PROPIONATE DIHYDRATE - A method for producing 3-(2,2,2-trimethylhydrazinium)propionate dihydrate by saponification of salts of 3-(2,2,2-trimethylhydrazinium)propionate esters with subsequent purification step using saturation with carbon dioxide or sulphur dioxide in alcoholic solution. | 2009-12-24 |
20090318732 | Dialdehyde compound, preparation method thereof, and synthetic method of carotenoids using the same - The novel C dialdehyde compound which can be efficiently utilized in the synthesis of carotenoid compounds based on the sulfone chemistry, the preparation method of the same, and the expeditious and practical synthetic processes for lycopene and β-carotene by the use of the above novel compound are disclosed. The syntheses of lycopene and β-carotene are characterized by the processes of the coupling reaction between two equivalents of geranyl sulfone or cyclic geranyl sulfone and the above C dialdehyde, the functional group transformation reactions of the diol in the resulting C 40 coupling products to X's (either halogens or ethers), and the double elimination reactions of the functional groups of the benzenesulfonyl and X to produce the fully conjugated polyene chain of the carotenoids. | 2009-12-24 |
20090318733 | METHOD FOR PURIFYING CYCLIC KETONES - The present invention relates to a process for purifying a composition (I) comprising at least one cyclic ketone having from 7 to 16 carbon atoms, which comprises thermal treatment of the composition (I) with a catalyst comprising at least one transition metal and further purification by means of a process selected from the group consisting of distillation, extraction and crystallization. Furthermore, the present invention relates to a process for preparing cyclododecanone, which comprises such a purification, and the use of at least one catalyst comprising at least one transition metal for purifying a composition (I) comprising at least one cyclic ketone having from 7 to 16 carbon atoms by thermal treatment of the composition (I) with a catalyst comprising at least one transition metal. | 2009-12-24 |
20090318734 | IONIC ADDITIVE FOR CATALYSIS IN BIPHASIC REACTION SYSTEMS - An additive for improving the rate of catalysis in biphasic reaction systems is disclosed. The additive is an ionic molecule comprising an organic cation such as a heterocyclic compound or a quaternary ammonium or phosphonium cation, and an anion which may be organic or inorganic. A process for improved catalysis in an aqueous biphasic system wherein the catalyst is substantially dissolved in the aqueous phase and the substrate is substantially contained in the non-aqueous phase is also described. A suitable additive is 1-octyl-3-methylimidazolium halide. Examples of suitable catalytic reactions include the hydrogenation, hydrosilation, hydroboration, hydrovinylation, hydroformylation, oxidation and hydroxycarbonylation of alkenes, and Heck, Suzuki, Stille, and Sonigashira coupling. | 2009-12-24 |
20090318735 | PREPARATION OF GLUTARALDEHYDE - Provided is a process for the preparation of glutaraldehyde. The process comprises reacting an alkoxydihydropyran with water in the presence of an acidic catalyst. The alcohol by-product distilled from the reaction mixture is subjected to a heterogeneous catalyst that is located external to the distillation column used for distilling the alcohol, thereby increasing glutaraldehyde yield and decreasing the level of alkoxydihydropyran contamination in the alcohol. | 2009-12-24 |
20090318736 | Production method of aromatic hydroxide - According to the present invention, two hydroxyl groups can be introduced into the 1-position and the 4-position of the benzene ring of an aromatic compound highly efficiently and highly selectively by a one step process to give the corresponding aromatic hydroxide. | 2009-12-24 |
20090318737 | Production of Paraffinic Fuel from Renewable Feedstocks - A process has been developed for producing fuel from renewable feedstocks such as plant and animal oils and greases. The process involves treating a first portion of a renewable feedstock by hydrogenating and deoxygenating in a first reaction zone and a second portion of a renewable feedstock by hydrogenating and deoxygenating in a second reaction zone to provide a diesel boiling point range fuel hydrocarbon product. If desired, the hydrocarbon product can be isomerized to improve cold flow properties. A portion of the hydrocarbon product is recycled to the first reaction zone to increase the hydrogen solubility of the reaction mixture. | 2009-12-24 |
20090318738 | SELECTIVE HYDROGENATION CATALYST AND PROCESS FOR ITS PREPARATION - The invention concerns a catalyst comprising palladium on an oxide of aluminium support. In the calcined state, the oxide of aluminium support has a diffractogram obtained by X ray diffraction comprising peaks which correspond to the following interplanar spacings and relative intensities: | 2009-12-24 |
20090318739 | NICKEL CATALYST FOR SELECTIVE HYDROGENATION - The present invention discloses a Ni-based catalyst useful in selective hydrogenation, comprising the following components supported on an alumina support: (a) 5.0 to 40.0 wt. % of metallic nickel or oxide(s) thereof; (b) 0.01 to 20.0 wt. % of at least one of molybdenum and tungsten, or oxide(s) thereof; (c) 0.01 to 10.0 wt. % of at least one rare earth element or oxide(s) thereof; (d) 0.01 to 2.0 wt. % of at least one metal from Group IA or Group IIA of the Periodic Table or oxide(s) thereof; (e) 0 to 15.0 wt. % of at least one selected from the group consisting of silicon, phosphorus, boron and fluorine, or oxide(s) thereof; and (f) 0 to 10.0 wt. % of at least one metal from Group IVB of the Periodic Table or oxide(s) thereof; with the percentages being based on the total weight of the catalyst. The catalyst is useful in the selective hydrogenation of a pyrolysis gasoline. | 2009-12-24 |
20090318740 | METHOD OF CONVERTING FEEDSTOCKS FROM RENEWABLE SOURCES TO GOOD-QUALITY DIESEL FUEL BASES USING A ZEOLITE TYPE CATALYST - The invention relates to a method of treating feedstocks from renewable sources in order to produce diesel fuel bases of excellent quality. The feedstocks used can be, for example, raw vegetable oils or such oils that have been previously subjected to a prerefining stage, animal fats, or mixtures of such feedstocks. The invention relates to a method allowing high diesel fuel base yields to be obtained from such feedstocks. | 2009-12-24 |
20090318741 | METHOD OF IMPROVING A DEHYDROGENATION PROCESS - The invention relates to a method of improving a dehydrogenation process comprising: removing a volume of a first dehydrogenation catalyst from a radial dehydrogenation reactor; loading the reactor with a volume of a second dehydrogenation catalyst that has a lower decline rate than the first dehydrogenation catalyst; and passing a dehydrogenatable hydrocarbon through the reactor wherein the volume of the second catalyst is at most 90% of the volume of the removed catalyst. | 2009-12-24 |
20090318742 | PROCESS FOR COMBINING THE CATALYTIC CONVERSION OF ORGANIC OXYGENATES AND THE CATALYTIC CONVERSION OF HYDROCARBONS - A process for combining the catalytic conversion of organic oxygenates and the catalytic conversion of hydrocarbons: an organic oxygenate feedstock is contacted with a Y-zeolite containing catalyst to produce a reaction stream, and a coked catalyst and a product stream are obtained after separating the reaction stream; a hydrocarbon feedstock is contacted with a Y-zeolite containing catalyst to produce a reaction stream, a spent catalyst and a reaction oil vapor are obtained after separating the reaction stream, and the reaction oil vapor is further separated to give the products such as gas, gasoline and the like; a part or all of the coked catalyst and a part or all of the spent catalyst enter the regenerator for the coke-burning regeneration, and the regenerated catalyst is divided into two portions, wherein one portion returns to be contacted with the hydrocarbon feedstock, and the other portion, after cooling, returns to be contacted with the organic oxygenate feedstock. This process not only reasonably utilizes the excessive thermal energy of the hydrocarbon conversion, but also solves the problem of heat supply for the conversion of the organic oxygenate, thus ensuring the continuous catalytic conversion of the organic oxygenate. | 2009-12-24 |
20090318743 | COMBINED CARBON DIOXIDE AND OXYGEN PROCESS FOR ETHYLBENZENE DEHYDROGENATION TO STYRENE - Processes for using a combination of carbon dioxide and oxygen in the dehydrogenation of hydrocarbons are provided. A hydrocarbon feedstock, carbon dioxide and oxygen are fed to an oxidative dehydrogenation reactor system containing one or more catalysts that promote dehydrogenation of the hydrocarbon feedstock to produce a dehydrogenated hydrocarbon product. The processes of the present invention may be used, for example, to produce styrene monomer by dehydrogenation of ethylbenzene using carbon dioxide and oxygen as oxidants. | 2009-12-24 |
20090318744 | SEPARATION PROCESS - A process is disclosed for the separation of solids from gases in a mixture which is most particularly applicable to an FCC apparatus. The mixture of solids and gases are passed through a conduit and exit through a swirl arm that imparts a swirl motion having a first annular direction to centripetally separate the heavier solids from the lighter gases. The mixture then enters a gas recovery conduit in which at least one plate radially extending from an inner wall impedes rotational motion of the mixture. The mixture enters cyclones at the other end of the gas recovery conduit without substantial swirling motion. | 2009-12-24 |