52nd week of 2011 patent applcation highlights part 39 |
Patent application number | Title | Published |
20110318382 | IMMUNOMODULATORY AGENTS AND METHODS OF USE - An antisense oligonucleotide compound, composition, vaccine and methods for treating a variety of conditions characterized by up-regulation of IL-10 in a mammalian subject are disclosed. The compound (i) is composed of morpholino subunits and phosphorus-containing intersubunit linkages joining a morpholino nitrogen of one subunit to a 5′ exocyclic carbon of an adjacent subunit, (ii) is capable of uptake by monocytes, lymphocytes, and dendritic cells in a mammalian subject, (iii) contains between 10-40 nucleotide bases, and (iv) has a base sequence effective to hybridize to at least 12 contiguous bases of a target sequence contained in an exon-2 or exon-4 slice site region of human IL-10 pre-mRNA. | 2011-12-29 |
20110318383 | HEMORRHAGIC FELINE CALICIVIRUS, CALICIVIRUS VACCINE AND METHOD FOR PREVENTING CALICIVIRUS INFECTION OR DISEASE - The present invention relates to a novel, isolated and purified hemorrhagic feline calicivirus FCV-DD1. The invention further embraces monovalent and multivalent vaccines containing the new FCV-DD1 strain. In addition, the invention encompasses methods of protecting felines against infection or preventing disease caused by feline calicivirus alone or in addition to other pathogens that comprises administering to the felines an immunologically effective amount of the monovalent and multivalent vaccines described herein. Also, the invention concerns methods for diagnosing or detecting the hemorrhagic feline calicivirus in a susceptible host, asymptomatic carrier and the like by detecting the presence of feline calicivirus FCV-DD1 or antibodies raised or produced against feline calicivirus FCV-DDI antigen. | 2011-12-29 |
20110318384 | VECTOR FOR TREATMENT VACCINE FOR STABLE AND CONSTITUTIVE HIGH-EXPRESSION CERVICAL CANCER AND RECOMBINANT LACTOBACILLUS TRANSFORMED BY THE SAME - A surface expression vector for preparing HPV vaccines, in which the surface expression vector contains a gene encoding a repE mutant protein having an amino acid sequence of SEQ ID NO: 1, a promoter, a poly-gamma-glutamate synthetase complex gene, and a gene which is linked with the poly-gamma-glutamate synthetase complex gene and encodes a tumor induction-associated antigen protein of human papillomavirus. | 2011-12-29 |
20110318385 | ENGINEERED BOTULINUM NEUROTOXIN C1 WITH SELECTIVE SUBSTRATE SPECIFICITY - An isolated polypeptide comprising a botulinum neurotoxin C1 light chain having a modified amino acid sequence relative to the sequence of a wild-type botulinum neurotoxin C1 light chain is disclosed. The modified botulinum neurotoxin C1 light chain is capable of selectively cleaving syntaxin protein, but has substantially reduced or no activity against SNAP-25 as compared to wild type botulinum neurotoxin C1 light chain, and is thus useful as a research tool and in medical treatment. | 2011-12-29 |
20110318386 | BACILLUS ISOLATES AND METHODS OF THEIR USE TO PROTECT AGAINST PLANT PATHOGENS - Methods of inducing systemic acquired resistance to infection in a plant by applying a composition comprising a | 2011-12-29 |
20110318387 | IMMUNIZATION METHOD USING CANCER CELLS - The object of the present invention is to provide an immunization method which allows efficient preparation of a desired antibody. | 2011-12-29 |
20110318388 | S1P Receptors Modulators and Their Use Thereof - The invention relates to novel compounds that have S1P receptor modulating activity. Further, the invention relates to a pharmaceutical comprising at least one compound of the invention for the treatment of diseases and/or conditions caused by or associated with inappropriate S1P receptor modulating activity or expression, for example, autoimmune response. A further aspect of the invention relates to the use of a pharmaceutical comprising at least one compound of the invention for the manufacture of a medicament for the treatment of diseases and/or conditions caused by or associated with inappropriate S1P receptor modulating activity or expression such as autoimmune response. | 2011-12-29 |
20110318389 | HUMAN PANCREATIC BETA CELL LINES FOR DIAGNOSTIC OF DIABETES - The present invention relates to a method for preparing commercial scale quantities of human functional Betacells and to the establishment of cell lines. It also relates to a method of diagnosis using Beta cell tumors or cells derived thereof. The method comprises sub-transplantation procedure to enrich the graft in proliferating Betacells, allowing to generate human Betacell lines. Such lines express little amount of insulin and have a gene expression profile that resembles to adult Betacells. In addition, the human Betacell lines are able to normalize glycemia of diabetic mice when transplanted, demonstrating their insulin secretion capabilities. | 2011-12-29 |
20110318390 | Bioactive Dose Having a Rapid Release Coating or Rapid Release Layer Containing a Material for Modulating pH of a Bodily Fluid to Help or Hinder Absorption of a Bioactive - A bioactive dose for delivering a bioactive agent to a mammal includes a solid bioactive dosage unit containing at least one bioactive agent and a rapid release coating provided on at least one outer surface of the solid bioactive dosage unit. The rapid release coating contains a material having a property of rapidly modulating a pH of bodily fluids in which the material comes in contact in a direction towards a pKa of the at least one bioactive agent and prior to the action of any buffer system internal to the dosage unit. In another embodiment, e.g., to aid oral quick dissolve forms in which it is not desirable to absorb the bioactive in the mouth, the rapid release coating contains a material having a property of rapidly modulating a pH of bodily fluids in which the material comes in contact in a direction away from a pKa of the at least one bioactive agent. | 2011-12-29 |
20110318391 | Bioactive Dose Having Containing a Material for Modulating pH of a Bodily Fluid to Help or Hinder Absorption of a Bioactive - A bioactive dose for delivering a bioactive agent to a mammal, includes a solid bioactive dosage unit containing at least one bioactive agent and a rapid release coating provided on at least one outer surface of the solid bioactive dosage unit, the rapid release coating containing a material having a property of rapidly modulating a pH of bodily fluids in which the material comes in contact in a direction towards an ideal absorptive pH or towards an ideal pH to hinder absorption of the at least one bioactive agent given the pKa that least at one bioactive agent. A modified liquid that is administered prior to, contemporaneous with, or following the delivery of a bioactive agent is also described. The liquid includes a pH modifier selected to control the pH of the liquid to a predetermined range so that the modified liquid rapidly modulates the pH of bodily fluids to enhance or hinder absorption of the bioactive agent. | 2011-12-29 |
20110318392 | DRUG COATING PROVIDING HIGH DRUG LOADING AND METHODS FOR PROVIDING THE SAME - The present invention is directed to aqueous drug coatings that include at least one insoluble drug, wherein the drug accounts for about 85 wt % to about 97 wt % of the drug coatings. A drug coating according to the present invention may include only one insoluble drug, two or more insoluble drugs, or one or more insoluble drugs in combination with one or more soluble drugs. The present invention also includes drug coating formulations suitable for providing drug coatings according to the present invention and dosage forms that include a drug coating according to the present invention. | 2011-12-29 |
20110318393 | Substituted Pyrazole Compounds - Provided are substituted pyrazole compounds which are useful as protein kinase inhibitors, compositions comprising the compounds, and methods of use thereof. The protein kinase inhibitors are particularly for inhibition of Aurora A (Aurora-2) protein kinase and are useful in the treatment of diseases associated with protein kinases, especially diseases associated with Aurora-2, such as cancer. | 2011-12-29 |
20110318394 | MULTI-LINKED STAR-SHAPED POLYMERS AND SYNTHETIC METHODS THERFOR - The invention describes new synthetic medical adhesives and antifouling coatings which exploit the key components of natural marine mussel adhesive proteins. | 2011-12-29 |
20110318395 | POLYHYDROXYALKANOATE MEDICAL TEXTILES AND FIBERS - Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate. These devices provide a wider range of in vivo strength retention properties than are currently available, and could offer additional benefits such as anti-adhesion properties, reduced risks of infection or other post-operative problems resulting from absorption and eventual elimination of the device, and competitive cost. The devices may also be particularly suitable for use in pediatric populations where their absorption should not hinder growth, and provide in all patient populations wound healing with long-term mechanical stability. The devices may additionally be combined with autologous, allogenic and/or xenogenic tissues to provide implants with improved mechanical, biological and handling properties. | 2011-12-29 |
20110318396 | DERMATOLOGICAL/COSMETIC COMPOSITIONS COMPRISING A RETINOID AND BENZOYL PEROXIDE - Dermatological/cosmetic compositions contain, in a physiologically acceptable medium, at least one retinoid, dispersed benzoyl peroxide and a gelling system comprising at least two categories of compounds. | 2011-12-29 |
20110318397 | METHOD FOR PREPARING HIGH PURITY GINSENOSIDE RD USING LACTOBACILLUS CASEI AND COSMETIC COMPOSITION FOR ANTI-WRINKLE COMPRISING THE HIGH PURITY GINSENOSIDE RD - The present invention relates to a method for preparing high-purity ginsenoside Rd using | 2011-12-29 |
20110318398 | COSMETIC COMPOSITION COMPRISING MOLECULAR ENCAPSULATED FERMENTED EXTRACT OF RHUS JAVANICA L. AS AN ACTIVE INGREDIENT - The present invention relates to a cosmetic composition comprising a composite prepared by molecularly encapsulating a fermented sumac ( | 2011-12-29 |
20110318399 | EMULSIFIED COSMETIC COMPOSITION - Disclosed is an emulsified cosmetic which is not sticky, has a long-lasting moisturizing effect, and can realize an excellent shiny sensation after application. Specifically disclosed is an emulsified cosmetic characterized by comprising (A) 0.1 to 15% by mass of a plate-like powder, (B) 0.1 to 30% by mass of an oil having an IOB value of 0.1 to 0.5, (C) 0.01 to 5% by mass of a pulverized agar gel, and (D) 1 to 20% by mass of a moisturizing agent. The plate-like powder preferably has an average particle diameter of 1 to 20 μm. The pulverized agar gel is one obtained by dissolving agar in water or an aqueous solvent, then allowing the agar solution to cool and solidify to form a gel, and pulverizing the gel. | 2011-12-29 |
20110318400 | Skin Care Product - The invention relates to a skin-care product comprising at least one component selected from the group of heat shock protein from alfalfa and heat shock protein hydrolysate from alfalfa. The invention further relates to the use of shock protein from alfalfa or hydrolysate thereof for slowing down the aging of the skin and/or for rejuvenating the skin. | 2011-12-29 |
20110318401 | TREATMENT OF LEG ULCERS USING PLACENTA DERIVED COLLAGEN BIOFABRIC - The present invention provides a method of treating a leg ulcer comprising contacting the leg ulcer with a collagen biofabric. The leg ulcer may be a venous, arterial, diabetic or decubitus (pressure) ulcer. The invention further provides kits comprising one or more pieces of collagen biofabric for the treatment of a leg ulcer. | 2011-12-29 |
20110318402 | TRICALCIUM PHOSPHATES, THEIR COMPOSITES, IMPLANTS INCORPORATING THEM, AND METHODS FOR THEIR PRODUCTION - Methods for the synthesis of tricalcium phosphates are presented, as well as a series of specific reaction parameters that can be adjusted to tailor, in specific ways, properties in the tricalcium phosphate precursor precipitate. Particulate tricalcium phosphate compositions having an average crystal size of about 250 nm or less are provided. Compositions of the invention can be used as prosthetic implants and coatings for prosthetic implants. | 2011-12-29 |
20110318403 | Preparation and Use of Pouteria Lucuma Extract - A method of preparing | 2011-12-29 |
20110318404 | Wound Dressing, Methods and Apparatus For Making Same and Storage and Use Thereof - Provided is a wound dressing prepared from whole blood that is clotted ex vivo to form a sheet of clotted blood that is applied onto the skin over a sight of skin injury. | 2011-12-29 |
20110318405 | Chemical Combination and Method for Increasing Delivery of Coenzyme Q10 - The present invention relates to a chemical combination and method for increasing delivery of Coenzyme Q10. The chemical combination comprises Coenzyme Q10 mixed with at least one chemical. The at least one chemical includes cyclic terpene containing essential oil(s) that permit unprecedented levels of Coenzyme Q10 to be made available for delivery and absorption, increasing bioavailability, as well as overcoming the previous limits. A transdermal patch including a layer containing Coenzyme Q10 is also provided. | 2011-12-29 |
20110318406 | Lecithin carrier vesicles and methods of making the same - A hydrated lecithin carrier vesicle composition includes a lecithin-derived membrane-forming lipid vesicle in conditioned water for incorporation of an active ingredient to form a dispersed composition. A method of making the hydrated lecithin carrier vesicle includes using lecithin having not more than about 80% w/w phosphatidylcholine in the presence of conditioned water. | 2011-12-29 |
20110318407 | INACTIVATED DENGUE VIRUS VACCINE WITH ALUMINIUM-FREE ADJUVANT - The present disclosure provides immunogenic compositions for the prevention and/or treatment of disease caused by dengue virus. | 2011-12-29 |
20110318408 | HLA CLASS I A2 TUMOR ASSOCIATED ANTIGEN PEPTIDES AND VACCINE COMPOSITIONS - A composition or vaccine composition comprising at least one peptide that has less than 600 contiguous amino acids having 100% identity to a native sequence of CEA, HER2/neu, MAGE2, MAGE3, or p53, the peptide further comprising at least one epitope selected from Table 6. | 2011-12-29 |
20110318409 | FRACTIONS OF WHEAT GERM FERMENT - The invention concerns wheat germ ferment, its biologically active fractions, the process for their production, the pharmaceutical preparations containing them and their uses. | 2011-12-29 |
20110318410 | RARE EARTH METAL COMPOUNDS, METHODS OF MAKING, AND METHODS OF USING THE SAME - Rare earth metal compounds, particularly lanthanum, cerium, and yttrium, are formed as porous particles and are effective in binding metals, metal ions, and phosphate. A method of making the particles and a method of using the particles is disclosed. The particles may be used in the gastrointestinal tract or the bloodstream to remove phosphate or to treat hyperphosphatemia in mammals. The particles may also be used to remove metals from fluids such as water. | 2011-12-29 |
20110318411 | MULTI-LAYERED ORALLY DISINTEGRATING TABLET AND THE MANUFACTURE THEREOF - The present invention features a tablet containing a first layer and a second layer, wherein: (i) the first layer includes a pharmaceutically active agent and the composition of the first layer is different from the composition of the second layer; (ii) the tablet has a density less than about 0.8 g/cc; and (iii) the tablet disintegrates in the mouth when placed on the tongue in less than about 30 seconds. | 2011-12-29 |
20110318412 | LOW DOSE DOXEPIN FORMULATIONS, INCLUDING BUCCAL, SUBLINGUAL AND FASTMELT FORMULATIONS, AND USES OF THE SAME TO TREAT INSOMNIA - The invention disclosed herein generally relates to low-dose oral doxepin pharmaceutical formulations and the use of these formulations to promote sleep. | 2011-12-29 |
20110318413 | EXTENDED RELEASE FORMULATIONS CONTAINING DARIFENACIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF - The present invention relates to an extended release formulation comprising darifenacin or pharmaceutically acceptable salts thereof and one or more release controlling hydrophobic materials optionally coated with combination of one or more release controlling hydrophobic materials and one or more release controlling hydrophilic materials; wherein said formulation provides controlled release of the darifenacin over the period of 24 hours. The present invention further relates to an extended release formulation comprising darifenacin or pharmaceutically acceptable salts thereof, wherein darifenacin is incorporated in a matrix comprising one or more release controlling hydrophobic materials and one or more release controlling hydrophilic materials. | 2011-12-29 |
20110318414 | REGENERATIVE TISSUE GRAFTS AND METHODS OF MAKING SAME - A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (MPCs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. MPCs can be harvested from debrided muscle tissue following orthopaedic trauma. The traumatized muscle-derived progenitor cells are a readily available autologous cell source that can be utilized to effect or improve wound healing in a variety of therapeutic settings and vehicles. | 2011-12-29 |
20110318415 | Hollow Gold Nanospheres (HAuNSs) and HAuNSs-Loaded Microspheres Useful in Drug Delivery - A near-infrared mediated drug delivery system comprising a plurality of microspheres made of polymeric material, each sphere containing a plurality of hollow gold nanospheres together with drug product, wherein upon NIR irradiation, the drug product is released from the microsphere. | 2011-12-29 |
20110318416 | BIORESORBABLE POLYMER MATRICES AND METHODS OF MAKING AND USING THE SAME - A bioerodible composition for delivery of a bioactive agent is the reaction product of a reaction mixture which includes an oxidized dextran solution, and a mixture of solids containing a dihydrazide, a bioactive agent, and optionally a pH adjusting agent in an amount sufficient to achieve a pH of the reaction mixture of 6 or less. The composition may include a release agent for the controlled release of the bioactive agent from the composition. A bioactive agent may therefore be administered to a body site in need of the same by providing a first aliquot portion of a reaction mixture comprising an oxidized dextran solution, and a second aliquot portion of a reaction mixture comprising a mixture of solids comprised of a dihydrazide, a bioactive agent, and a solid acid which is present in an amount sufficient to achieve a pH of the reaction mixture of 6 or less, mixing the first and second aliquot portions to form the reaction mixture thereof, and thereafter installing the reaction mixture at the body site and allowing a solidified bioerodible drug delivery composition to be formed thereby in situ. The present invention may be provided in the form of a kit comprised of a double syringe which respectively contains the first and second aliquot portions of the reaction mixture so that the same may be mixed just prior to use. | 2011-12-29 |
20110318417 | HIGHLY PURE CINACALCET OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF - Provided herein are impurities of cinacalcet, (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-(5,6,7,8-tetrahydronaphthalene)methaneamine (tetrahydro cinacalcet impurity), (R)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethaneamine-N-oxide (cinacalcet N-oxide impurity) and (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]methyl]-1-naphthalenemethaneamine (benzylamine impurity); and processes for preparation and isolation thereof. Provided further herein is a highly pure cinacalcet or a pharmaceutically acceptable salt thereof substantially free of impurities, processes for the preparation thereof, and pharmaceutical compositions comprising highly pure cinacalcet or a pharmaceutically acceptable salt thereof substantially free of impurities. | 2011-12-29 |
20110318418 | COMPOSITIONS OF 5-ETHYL-2--PYRIMIDINE - This invention relates to the field of pharmaceutical chemistry and, more specifically, to pharmaceutical formulations as well as to intermediates used to prepare such formulations and to methods for manufacturing such formulations. | 2011-12-29 |
20110318419 | GRAFT MATERIALS CONTAINING BIOACTIVE SUBSTANCES, AND METHODS FOR THEIR MANUFACTURE - Described are packaged, sterile medical graft products containing controlled levels of a growth factor such as Fibroblast Growth Factor-2 (FGF-2). Also described are methods of manufacturing medical graft products wherein processing, including sterilization, is controlled and monitored to provide medical graft products having modulated, known levels of a extracellular matrix factor, such as a growth factor, e.g. FGF-2. Preferred graft materials are extracellular matrix materials isolated from human or animal donors, particularly submucosa-containing extracellular matrix materials. Further described are ECM compositions that are or are useful for preparing gels, and related methods for preparation and use. | 2011-12-29 |
20110318420 | FULVESTRANT NANOSPHERE/MICROSPHERE AND PREPARATIVE METHOD AND USE THEREOF - Fulvestrant nanosphere/microsphere and preparation method and use thereof are provided in the present invention. The carrier material of the fulvestrant nanosphere/microsphere is methoxy ended polyethylene glycol-polylactic acid block copolymer. The nanosphere/microsphere is prepared by solvent-nonsolvent method, in-liquid drying method and/or spray drying method, and has the features of high drug loading and high encapsulation efficiency, controllable release of medicine and no irritant to application site or blood vessel. The fulvestrant nanosphere/microsphere can be used to treat metastatic advanced breast cancer in post-menopausal woman. | 2011-12-29 |
20110318421 | SURFACE FUNCTIONALIZED CERAMIC NANOPARTICLES - The present disclosure is directed to surface functionalized ceramic nanoparticles. The method for producing the surface functionalized ceramic nanoparticles generally includes at least four distinct steps: 1) synthesis of an amphiphilic surfactant having the desired surface functionality, 2) formation of mixed solvent microstructured solution with the surfactant, 3) synthesis of the desired ceramic within the microstructured solution, and 4) chemical attachment of the surfactant to the ceramic nanoparticle. The composition of the surface functionalized nanoparticle comprises a lipophilic component, a hydrophilic component, a chelating agent and a ceramic forming component. | 2011-12-29 |
20110318422 | TARGETED ACTIVE AGENT DELIVERY SYSTEM BASED ON CALCIUM PHOSPHATE NANOPARTICLES - Calcium phosphate nanoparticle active agent conjugates are described. Specifically, anticancer agent conjugates are prepared which are suitable for targeted active agent delivery to tumor cells and lymphatics for the treatment of cancer and the treatment or prevention of cancer metastasis. | 2011-12-29 |
20110318423 | Methods and Apparatus for Creating Particle Derivatives of HDL with Reduced Lipid Content - The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL. These derivatives of HDL are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol levels in cells, tissues, organs, and blood vessels. The present method is useful for treating atherogenic vascular disease and may be combined with other therapies such as statins, inhibitors of cholesterol absorption, niacin, anti-inflammatories, exercise and dietary restriction. | 2011-12-29 |
20110318424 | METHODS FOR PROLONGING VIABILITY OF CONE CELLS USING MODULATORS OF THE MAMMALIAN TARGET OF RAPAMYCINE (mTOR) - The present invention is directed to the use of modulators of the mammalian target of rapamycine (mTOR) pathway, glucose and/or glucose enhancers for treating retinal disorders and, in particular, for prolonging the viability of cone cells. | 2011-12-29 |
20110318425 | TREATMENT OF INTERSTITIAL CYSTITIS USING (6aR, 10aR)- DELTA-8-TETRAHDRAOCANNABINOL-11-OIC ACIDS - The present invention relates to non-psychoactive derivatives of tetrahydrocannabinol, which are useful in treating interstitial cystitis and relieving symptoms thereof. The invention uses (6aR,10aR)-Δ | 2011-12-29 |
20110318426 | ANTIBACTERIAL AGENT AND METHOD OF USING THE SAME - An antibacterial agent of the present invention contains a metal-containing compound containing a metal other than aluminum, and a phosphorus-adsorbing material. A method of using an antibacterial agent of the present invention is a method for improving an antibacterial property of a metal-containing compound containing a metal other than aluminum, wherein the metal-containing compound and a phosphorus-adsorbing compound are used in combination. Thus, the present invention provides an antibacterial agent, and a method of using an antibacterial agent, wherein an antibacterial property of a metal-containing compound containing a metal other than aluminum, particularly a silver-containing compound, is improved significantly. | 2011-12-29 |
20110318427 | FUNGICIDAL COMPOSITIONS BASED ON COPPER SALTS - Fungicidal compositions are described, comprising:
| 2011-12-29 |
20110318428 | TREATMENT SOLUTION FOR TREATING WOUNDS, IN PARTICULAR FOR LIQUID WOUND TREATMENT - The invention relates to a treatment solution for treating wounds, preferably for liquid wound treatment of acute and chronic wounds, made of an aqueous solution including zinc, iron, and acid, wherein the per liter proportion of zinc is 10 to 100 mg, the proportion of iron is 6.5 to 60 mg, and the proportion of acid is selected such that the pH value of the treatment solution is 2.5 to 3.5. | 2011-12-29 |
20110318429 | Uses of an Immunomodulatory Protein (GMI) from Ganoderma Microsporum - The invention provides a method for inhibiting EGF receptor activity comprising contacting an EGF receptor with an immunomodulatory protein (GMI) from | 2011-12-29 |
20110318430 | TUMOR THERAPY WITH ANTITUMOR AGENTS IN COMBINATION WITH SINDBIS VIRUS-BASED VECTORS - A method for treating malignant tumors with Sindbis viral based vectors in combination with antitumor agents and pharmaceutical formulations for use in such treatment. | 2011-12-29 |
20110318431 | Pharmaceutical Compositions and Methods of Treating Neurological Insults - A pharmaceutical composition containing a magnesium salt and an osmotic hypertonic agent, like a mannitol, is disclosed. Also disclosed are methods of treating individuals who have suffered a neurological insult, such as traumatic brain injury. | 2011-12-29 |
20110318432 | COMPOSITIONS FOR THE TREATMENT OF GASTRO-ESOFAGEAL REFLUX DISEASE (GERD) - Oral pharmaceutical, nutraceutical, health foods and medical device compositions based on polysaccharides from | 2011-12-29 |
20110318433 | SOOTHING PHARMACEUTICAL OR COSMETIC COMPOSITION COMPRISING A PEPTIDE THAT ACTIVATES HMG-COA REDUCTASE - The present invention relates to a soothing cosmetic or pharmaceutical composition comprising at least one peptide that activates human HMG-CoA reductase of general formula (I): | 2011-12-29 |
20110318434 | Acne Vulgaris Treatment Regimen - An improved method, formulation and kit for the treatment of acne vulgaris are disclosed. The formulation is effective in inhibiting or killing the | 2011-12-29 |
20110318435 | Composition comprising longan arillus extract or combined extract comprising the same for treating neurodegenerative disease - This disclosure relates to a composition for prevention or treatment of neurodegenerative disease comprising longan arillus extract, or combined extract comprising longan arillus. The composition exhibits remarkably excellent prevention or treatment effect of neurodegenerative disease by containing longan arillus extract or combined extract comprising longan arillus, and particularly, it may effectively prevent or treat neurodegenerative disease by significantly protecting dopaminergic neurons from neurotoxicity due to MPTP selectively acting on dopaminergic nervous system and neurotoxicity due to aggregation of alpha-synuclein proteins. | 2011-12-29 |
20110318436 | HERBAL SOLID FORMULATION AND PROCESS FOR PREPARING THE SAME - Disclosed is a herbal solid formulation of | 2011-12-29 |
20110318437 | COMBINATIONS OF HERB EXTRACTS HAVING SYNERGISTIC ANTIOXIDANT EFFECT, AND METHODS RELATING THERETO - The present invention comprises mixtures of herb extracts, namely a mixture of the herb ginger and the herb sophora, which which mixture exerts synergistic antioxidant effect. Skin care preparations incorporating such herb extract mixtures, and their methods of preparation and use, are also claimed. | 2011-12-29 |
20110318438 | PHARMACOLOGICALLY EFFECTIVE COMPOSITION OF HERBS FOR TREATMENT ON SYMPTOMS OF INFLUENZA AND COLDS - A pharmacologically effective composition of herbs is provided for symptom relieving for influenza and colds. The composition that is antiviral, antibacterial and does not contain any undesirable stimulants such as caffeine. | 2011-12-29 |
20110318439 | PLANT EXTRACTS FROM ACRONYCHIA SPECIES AND THEIR USE - The invention relates to plant extracts and bioactive molecules derived from the plant genus | 2011-12-29 |
20110318440 | DIE PLATE FOR AN UNDERWATER TYPE PELLETIZER - The invention relates to a die plate ( | 2011-12-29 |
20110318441 | MOULDING PLANT FOR MANUFACTURING A STORAGE CONTAINER FOR STORAGE OF NUCLEAR RADIATION MATERIAL - A method and a moulding plant for manufacturing a storage container for storage of nuclear radiation material, the container having an inner container part of a first thermoplastic material, an intermediate container part of radiation inhibiting material on the outside of the inner container part, and an outer container part of a second thermoplastic material moulded onto the outside of intermediate container part. First, second, third and fourth locations are present along a circular path. First, second and third sets of outer mould means are provided at said second, third and fourth locations, respectively, for enabling injection moulding of said inner container part, said intermediate container part and said outer container part, respectively, thereat and at least one mould core or a plurality of mutually spaced mould cores being movable by means of a rotary turntable to successively move from the first location to the second location, then from the second location to the third location, then from the third location to the fourth location, and then from the fourth location back to the first location. | 2011-12-29 |
20110318442 | APPARATUS FOR PRODUCING MONOFILAMENTS OR RIBBONS - The invention relates to an apparatus for producing monofilaments or ribbons which are guided in parallel through several treatment devices in an extrusion process. For this purpose, an extrusion device is connected downstream in several treatment device, wherein for guiding the monofilaments or ribbons at least one rod-shaped guide element is provided which has a contact surface for guiding the ribbons or monofilaments. In order to enable low-friction and wear-resistant guidance, in particular when using very elastic monofilaments or ribbons, the contact surface has a multiple coating comprising several coating materials that are applied in several single coatings, each with a different layer thicknesses, wherein the single coatings are formed in a sandwich-like manner on the contact surface. | 2011-12-29 |
20110318443 | PLACING AND REMOVING DEVICE FOR INSERT MOLDED ARTICLE - A device for removing an insert molded article and simultaneously placing a preformed item, includes a bracket; a removing mechanism slidably mounted to the bracket, the removing mechanism comprises a suck for sucking the insert molded article; a placing mechanism slidably mounted to the bracket, the placing mechanism comprises a holding base for holding the preformed item; a first driving element mounted to the bracket and connected to the removing mechanism to drive the removing mechanism to slide relative to the bracket; and a second driving element mounted to the bracket and connected to the placing mechanism to drive the placing mechanism to slide relative to the bracket. | 2011-12-29 |
20110318444 | Material Supply for a Tablet Pressing Machine and a Tablet Pressing Machine - The present invention relates to a material supply for a tablet pressing machine with a rotor which comprises a matrix disc. A plurality of matrices is arranged within the matrix disc. The material supply is provided to supply material which is to be tabletted to the matrices formed in the matrix disc. A further subject of the invention is a tablet pressing machine which comprises a material supply according to the invention. | 2011-12-29 |
20110318445 | METHOD AND DEVICE FOR PLACING THIN MATERIAL LAYERS ONTO A RELIEF MOULD - The present invention relates to a method and a device for placing at least one material layer onto a relief mould for producing a composite material. Thereby, an elastically-reversibly deformable body with a surface relief that is designed to correspond to the relief mould is pressed against the material layer, as a result of which the surface of said body is deformed, and the material layer can be picked up. As a result of its elastically-reversible characteristics the body subsequently deforms back to its initial state so that the material layer can easily be placed onto the relief mould. | 2011-12-29 |
20110318446 | Method And An Apparatus For The Manufacture Of Concrete Pipes - A method and an apparatus for the manufacture of concrete pipes ( | 2011-12-29 |
20110318447 | Angled Core-Pulling Mechanism of Mold - An angled core-pulling mechanism of mold includes a core insert, a shaping core and a slide block of which a rear end longitudinally defines a slide passage having a bottom side slanted downward from front to rear. The core insert defines a shaping cavity, a slide hole extending downward and slanting forward with a top communicating with the shaping cavity, and a receiving fillister having a level bottom face and with a top being connected with a bottom of the slide hole. One end of the shaping core is slantwise slidably disposed in the slide passage, and the other end is slantwise slidably disposed in the slide hole. The slide block can longitudinally move along the bottom face to drive the shaping core to slide slantwise upward and downward along the slide hole so that the shaping core can be inserted into or withdrawn out of the shaping cavity. | 2011-12-29 |
20110318448 | DEER ATTRACTANT AND NUTRIENT - The embodiments of the Deer Attractant and Nutrient is a deer attractant and feed comprising rice hulls; calcium carbonate; manganese; copper sulfate; zinc sulfate; trace amounts of cobalt carbonate; EDDI; mono DICAL; selenium; and power sweet. Because of the balanced nutritional components of the Deer Attractant and Nutrient the product enhances overall deer growth including antler growth in bucks. The Deer Attractant and Nutrient also acts as a deer attractant, causing the deer to move toward a supply of the attractant. | 2011-12-29 |
20110318449 | Phytase-Containing Animal Food and Method - A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described. | 2011-12-29 |
20110318450 | CHEWABLE POUCH FOR FLAVORED PRODUCT DELIVERY - Provided is a disintegrable or non-disintegrable oral flavor delivery product. The product includes a disintegrable or non-disintegrable chewable pouch with a plurality of perforations. The pouch encloses a non-tobacco flavor product that can be in a gel, semi-liquid, and/or liquid form. A user chews, sucks, and/or manipulates the pouch to cause the enclosed flavor product to leach out of the perforations into the user's mouth. | 2011-12-29 |
20110318451 | FERMENTATION METHOD AND APPARATUS ADAPTED FOR THE METHOD - A method for treating a vegetable product in the form of crushed material includes the steps of (i) storing the crushed material in a first vat to let it ferment and form a cap of solid parts floating on a liquid mass therein; (ii) connecting a second vat to the first one to gather in it the gaseous products generated due to fermentation; (iii) isolating the two vats; (iv) reducing the gaseous pressure in the first vat; (v) connecting the second vat to the first at a point beneath the cap so that, due to the differential pressure between the two vats, spontaneous racking of gaseous products in the liquid mass occurs, in such a manner that rising they get into contact with the cap. | 2011-12-29 |
20110318452 | Nutritionally Enhanced Pasta - The invention provides for the use of a texture modifying agent added to nutritionally enhanced pasta dough, such as pasta dough with high levels of protein, so that a pasta product can be produced with a quality similar to that of conventional pasta. The texture modifying agent, which preferably includes an enzyme, permits the nutritionally enhanced pasta dough to be extruded in conventional pasta manufacturing equipment and to form a pasta product with a texture similar to typical semolina-based pasta. | 2011-12-29 |
20110318453 | METHOD FOR PRODUCING FATS AND OILS - The present invention discloses a safer, more effective and industrially suitable method for producing fats and oils rich in a XUX triglyceride wherein the contents of a XXX triglyceride and a XX diglyceride are low which comprises, upon removing by crystallization a XXX triglyceride and a XX diglyceride each of which is contained in fats and oils comprising 50 to 90 mass % of a XUX triglyceride in total triglycerides, the step of conducting such removing by crystallization in the presence of a fatty acid lower alkyl ester. This method is a more efficient and industrially suitable method for producing fats and oils rich in a XUX triglyceride wherein the contents of a XXX triglyceride and a XX diglyceride are low. | 2011-12-29 |
20110318454 | NUTRITIONAL BEVERAGE AND A METHOD OF MAKING THE SAME - A refreshingly acidic beverage which is a potent mineralizing drink and a method of making it is described. It is made from grains, preferably barley and soy and contains physiological supplements of calcium, magnesium and amino acids that can be well assimilated. The method involves use of enzymes, including a carbohydrate oxidase and a catalase during brewing. | 2011-12-29 |
20110318455 | PRODUCTION OF BEADLETS COMPRISING PROBIOTIC COMPOUNDS - The present invention relates a process of production of beadlets comprising probiotic compounds in a matrix comprising at least one starch and/or starch derivative, to such beadlets and to the use of such specific beadlets in food (for mans and animals) as well as in premixes. | 2011-12-29 |
20110318456 | BARBECUE CHOCOLATE DIP SET - A set for preparing molten chocolate or a chocolate dip on a barbecue which includes chocolate and a suitable cooking container for melting the chocolate using the heat of a burning barbecue, whereby the chocolate is provided as a suitable chocolate formulation and preferably also in a suitable form for being molten in the cooking container using the heat of a burning barbecue. | 2011-12-29 |
20110318457 | Pet Meal Kit - The meal kit container of the present invention contains a disposable package which an animal can be feed by using a complete ready-to-use animal meal kit that can be disposed of after use. The invention comprises a meal kit whose components consist of a heat sealed locking closure pouch sufficient to store dry animal food, a locking closure pouch sufficient to hold water and a heat sealed pouch sufficient to hold an edible animal cookie or similar animal treat. | 2011-12-29 |
20110318458 | PROCESSING AND PACKAGING MEAT WITHOUT USING HIGHLY ABSORBENT MATERIAL - The present invention is in the field of meat processing and packaging. Specifically, the invention is a packaged uncooked treated meat product with increased moisture retention, thereby eliminating the need for highly absorbent material in the package. | 2011-12-29 |
20110318459 | FLAVOURING COMPOSITIONS AND METHODS FOR MAKING SAME - Methods for synthesizing traditional balsamic vinegar, conventional balsamic vinegar, and Parmesan cheese flavouring compositions are provided for easily synthesizing these flavourings for use in or with food products for flavour addition, enhancement, and/or substitutes for flavourings typically obtained only after long aging methods. | 2011-12-29 |
20110318460 | METHOD FOR REDUCING HEADSPACE AND MODIFYING ATMOSPHERE IN A FOOD PACKAGE - Methods are disclosed of assembling a food package using an absorbent pad having an active agent that generates an atmosphere-modifying gas into the headspace after the food package is sealed, to compensate for losses of atmosphere-modifying gases injected in the food package prior to sealing. The methods of assembly reduce the headspace requirements and overall dimensions of the food package. The methods further prevent or reduce collapse of the food package or having the lid film contact the food product. | 2011-12-29 |
20110318461 | PERACID AND 2-HYDROXY ORGANIC ACID COMPOSITIONS AND METHODS FOR TREATING PRODUCE - Methods and compositions for treating produce to control microorganisms are provided. The method treats produce by contacting the surface of the produce with an aqueous solution comprising i) an organic peracid of the formula RC(O)OOH wherein R is methyl, ethyl, n-propyl, or s-propyl; ii) a 2-hydroxy organic acid selected from tartaric acid, citric acid, malic acid, mandelic acid, and lactic acid; and (optionally) iii) an anionic surfactant; wherein the aqueous solution has a pH from 2.5 to 6.0. | 2011-12-29 |
20110318462 | Method and Apparatus For An Ice Cream Scooper - A method and apparatus for an ice cream scooper. The apparatus includes at least four tines. The four tines are mechanically coupled to a retractable handle, and the retractable handle has a first position and a second position. The first position causes the four tines to be held in an open arrangement and the second position causes the four tines to be held in a closed arrangement. Each of the four tines is shaped to enable penetration of an ice cream surface when a downward force is applied to the retractable handle while the retractable handle is in the first position and the four tines are set in the open arrangement. Other embodiments are also disclosed. | 2011-12-29 |
20110318463 | System and Method for Pasteurizing Milk - Systems and methods are provided for pasteurizing milk or other fluids, and for cleaning and disinfecting processing passageways prior to and after the milk processing. The disclosed pasteurization systems and methods have very low impact on the characteristics of raw, unpasteurized milk (e.g., texture, flavor, and/or nutritional value). For example, some systems and methods utilize a pump that operates at a very low flow rate (e.g., about 1 gallon per minute (GPM)) to prevent mechanical adulteration of the raw milk. Disclosed systems and methods for cleaning and disinfecting the fluid passageways also utilize a low-flow rate, and can use the same low flow pump that is utilized during pasteurization. A pressure pulser allows pressure to build up within the fluid passageways despite the low flow, and then releases the pressure to purge air from the passageways and to cause their interior surfaces to contact the cleaning fluid. | 2011-12-29 |
20110318464 | SWEETNESS ENHANCERS, SWEETNESS ENHANCED SWEETENER COMPOSITIONS, METHODS FOR THEIR FORMULATION, AND USES - The present invention relates generally to sweetness enhancers capable of enhancing the sweet taste of sweetener compositions and the sweetener compositions produced therefrom. In particular, the present invention relates to sweetener compositions comprising sulfamates capable of enhancing the sweetness of the sweetener composition. | 2011-12-29 |
20110318465 | EFFERVESCENT CARRIER, A METHOD OF CHANGING THE FLAVOR OF MILK AND AN EFFERVESCENT TABLET FOR CHANGING THE FLAVOR OF MILK - An effervescent tablet that includes an effervescent agent that includes an acid component selected from the group consisting of an acid salt, an acid anhydride, and combinations thereof, and a base, binder, and lubricant, the effervescent tablet disintegrating when placed in milk to form a milk beverage that is free of noticeable curdling. | 2011-12-29 |
20110318466 | INSTANT DRIED NOODLES AND PROCESS FOR PRODUCING THE SAME - Instant dried noodle, which has been prepared by a method wherein a dough is made under a degassing condition, the dough is formed into noodle strips an usual manner, gelatinizing the noodle strips, cutting the noodle strips so to contain the resultant cut product thereof in a molding basket, and drying the noodle strips with hot air. A solid fat or oil, and/or an emulsifier has been added to the raw material for dough. There is provided instant dried noodle, which has a viscoelasticity (such as textures including stiffness, elasticity, viscosity and chewing property), which has never been attained the non-fried noodles in the prior art. | 2011-12-29 |
20110318467 | Hydroxypropyl Substituted Starches As Source of Soluble Fiber - The present invention relates to a food product with high levels of ethanol soluble fiber and total dietary fiber and methods of making the same. In particular, the food product contains at least one food ingredient and a modified high hydroxypropyl substituted starch. The modified starch is suitable as a non-animal derived gelatin replacement in foods traditionally prepared with gelatin and may also be used in extruded food products. | 2011-12-29 |
20110318468 | FRUCTOSE-BASED ANTI-DIABETIC ALCOHOLIC BEVERAGE AND METHOD OF MAKING SAME - An alcoholic beverages made from topinambour bulbs that does not contain sugar syrups, glucose or vinegar acids. The topinambour bulb-based beverages utilize a specific acid-hydrolysis utilizing multiple organic acids which results in an extract that contains fructose polysaccharide components that are beneficial for diabetes prevention. For taste and for diabetes-preventing purposes, natural multi-atomic (3, 5 and 6 atoms) alcohols are also utilized. Natural colorings are optionally added to provide a desirable appearance to the beverage. | 2011-12-29 |
20110318469 | Barley with reduced lipoxygenase activity and beverage prepared therefrom - According to the invention, there is provided barley with total loss of functional lipoxygenase (LOX)-1 and LOX-2 enzymes, and plant products produced thereof, such as malt manufactured by using barley kernels defective in the synthesis of the fatty acid-dioxygenating enzymes LOX-1 and LOX-2. Said enzymes account for the principal activities related to dioxygenation of linoleic acid into 9- and 13-hydroperoxy octadecadienoic acid, respectively. 9-Hydroperoxy octadecadienoic acid represents a LOX pathway metabolite, which—through further enzymatic or spontaneous reactions—may lead to the appearance of trans-2-nonenal (T2N). The invention enables brewers to produce a beer having insignificant levels of stale, T2N-specific off-flavors, even after prolonged storage of the beverage. | 2011-12-29 |
20110318470 | Method For Improving Plant Health - A method for improving the health of a plant, which method comprises treating the plant and/or the locus where the plant is growing or is intended to grow and/or the plant propagules with a plant health improving amount of at least one benzoyl-substituted alanine compound (A) of the formula I. | 2011-12-29 |
20110318471 | PROCESSING TECHNIQUE TO THAW PARTIALLY FROZEN FRUITS AND VEGETABLES AND INCORPORATING SOLIDS - A method for thawing and infusing partially frozen fruits or vegetables. Individually quick frozen fruits or vegetables are introduced into a mixing kettle. An infusion solution is circulated from a solution tank, through a bed of fruits or vegetables, and back to a solution tank. The infusion solution is maintained at a temperature of about 45° to about 50° F. and at a Brix of about 40° to about 50°. The infusion solution is pumped and circulated at a high rate which reduces thaw time but does not result in product degradation. After thawing, the pumping and re-circulating rate is decreased to allow for increased infusion efficiency. Pressure pulses are applied to the product in the mixing tank which decreases the infusion time. Thus, thawed and infused fruit and vegetables are produced quickly and with minimal product degradation. | 2011-12-29 |
20110318472 | LOW FAT CONTENT CHIP-LIKE CEREAL SNACK - There is described a cereal-based chip-like snack having a very reduced total fat content and an improved shelf-life and a process for the production thereof which comprises the steps of cooking, drying, flaking and toasting. Specifically, chips according to the present invention have size and thickness completely similar to those of the traditional chips. Therefore, they are a highly valid and useful alternative to traditional chips, not only in terms of nutritional and dietetic values, but also in terms of appearance, agreeableness and crispness. | 2011-12-29 |
20110318473 | GENERATION OF PLANTS WITH ALTERED PROTEIN, FIBER, OR OIL CONTENT - The present invention is directed to plants that display an improved oil quantity phenotype or an improved meal quality phenotype due to altered expression of an IMQ nucleic acid. The invention is further directed to methods of generating plants with an improved oil quantity phenotype or improved meal quality phenotype. | 2011-12-29 |
20110318474 | FOOD PRODUCTS ENRICHED WITH METHYLXANTHINES - A food product enriched with one or more methylxanthines is provided. The food product comprises a total amount of from 100 to 3000 milligram of methylxanthines per unit amount of the food product, and further comprises a polymeric polyphenol compound that has a molecular weight equal to or above 500 gram per mole and which is complexed with the one or more methylxanthines, wherein the weight ratio of the polymeric polyphenol compound to the one or more methylxanthines is from 10:1 to 1:10 A method for the production of such food products is also provided. | 2011-12-29 |
20110318475 | METHODS AND APPARATUS FOR FORMING CONTOURED EDIBLE PIECES - A method for forming thin edible pieces uses two continuous belts that cooperate to form a fill cavity. An edible mass, such as chocolate, is flowed into the fill cavity where it forms an edible blank which is transported on a belt path with the two belts moving in tandem. After the edible blank is released from the first or second continuous belt, a three-dimensional shape may be imparted to the edible blank at a forming station using one or more stamping dies or a forming drum. Using the techniques and apparatus described herein, novel edible products, and particularly novel chocolate products, can be made having shape characteristics that cannot be obtained using known molding or forming techniques. | 2011-12-29 |
20110318476 | POROUS AND NONPOROUS MATERIALS FOR TISSUE GRAFTING AND REPAIR - Implants having improved mechanical properties and/or degradation profiles, kits including such implants, and methods of producing and using the same. | 2011-12-29 |
20110318477 | Apparatus and method for producing a sheet material - Provided is an apparatus for producing a sheet material including: an RFID reader ( | 2011-12-29 |
20110318478 | PARTICLES AND INKS AND FILMS USING THEM - Particles and particle films are provided. In certain examples, particles produced from a single phase process may be used to provide industrial scale synthesis of particles for use in devices such as printed wiring boards. | 2011-12-29 |
20110318479 | METAL PLATING COMPOSITIONS AND METHODS - Disclosed are metal plating compositions and methods. The metal plating compositions provide good leveling performance and throwing power. | 2011-12-29 |
20110318480 | Method of manufacturing substrate using a carrier - A method of manufacturing a substrate using a carrier, that includes preparing a carrier having a releasing layer, and insulating layers and metal layers sequentially disposed on both sides of the releasing layer; patterning the metal layers to form base circuit layers; forming buildup layers on the base circuit layers; executing a routing process to separate the insulating layers from the releasing layer; and forming solder resist layers on the buildup layers and forming openings in the solder resist layers and the insulating layers to expose pads. | 2011-12-29 |
20110318481 | Method for Preparing Metallic Thin Film - Provided is a method for manufacturing a metal film, including: coating or printing a metal ink containing an organic metal complex on a substrate; and necessrily parallel-performing a pressure process during a procedure of forming metal particles by firing the metal ink, thereby forming a conductive metal film. The present invention can provide a method for manufacturing a metal film capable of improving film characteristics such as conductivity, reflectance, and uniformity in thickness, and the like, as well as remarkably shortening the time for forming the metal film, thereby efficiently manufacturing a superior-quality metal film. | 2011-12-29 |