Abedini
Andisheh Abedini, Jefferson City, MO US
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20100021390 | Fluorescent Analogs Of The Islet Amyloid Polypeptide - The present invention relates to methods and compositions for the investigation of amyloid formation. In preferred embodiments, amyloid formation associated with type II diabetes is monitored by fluorescence spectroscopic measurements of the activity of p-cyano-phenylalanine-substituted islet amyloid polypeptide, and derivatives thereof, under an amyloid-forming condition. In some embodiments, the amyloid-forming condition is associated with a diseased, or putatively diseased, cell or tissue. In some embodiments, the invention provides a method of evaluating the severity of the amyloid-forming condition, and changes therein induced by agents that inhibit, or potentially inhibit, amyloid formation. | 01-28-2010 |
Andisheh Abedini, New York, NY US
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20130022620 | ASSAYS AND METHODS PERTAINING TO PRE-AMYLOID INTERMEDIATES - The present invention relates to amyloidogenic peptides, polypeptides and proteins; and methods for screening to identify modulators of polypeptide self-aggregation into amyloids. The invention further relates to assays and methods using islet amyloid polypeptide (IAPP) as a component of a model system with which to screen for modulators of islet amyloid formation and accumulation. Also encompassed are modulators identified using the assays and methods described herein and compositions comprising same. The present invention also relates to methods and compositions for modulating amyloid formation and accumulation, thereby providing novel treatments for amyloidoses. In a particular aspect, methods and compositions are presented for inhibiting islet amyloid formation and accumulation, thereby providing novel treatments for diabetes. | 01-24-2013 |
Navid Abedini, Raritan, NJ US
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20150063343 | RESOURCE ALLOCATION FOR DISTRIBUTED DEVICE-TO-DEVICE SYNCHRONIZATION - Methods, systems, and devices are described for synchronizing a user equipment (UE) in a device-to-device communications network. The UE may scan for a synchronization signal transmitted from another UE in the network. A synchronization frame including a plurality of slots to use may be identified based at least in part on a result of the scanning. The identified synchronization frame may be analyzed to select a slot to use from the plurality of slots of the synchronization frame. A synchronization signal may be transmitted using the identified synchronization frame and the selected slot. | 03-05-2015 |
20150078369 | METHOD AND APPARATUS FOR DISSEMINATION OF TIMING INFORMATION IN DISTRIBUTED SYNCHRONIZATION DEVICE TO DEVICE NETWORKS - A method, an apparatus, and a computer program product for wireless communication are provided in connection with improving convergence to a common timing structure for devices in a distributed synchronization D2D network. In an example, a communications device is equipped to detect, by a UE, a synchronization signal during a listening slot duration scan of a communication channel. In an aspect, the listening slot duration may be defined based on a first timing structure, and the synchronization signal may be defined based on a second timing structure. The communications device may further be equipped to obtain timing information associated with the second timing structure from the synchronization signal, and determine whether the first timing structure or the second timing structure is a preferred timing structure. | 03-19-2015 |