Patent application number | Description | Published |
20130084298 | NOVEL ANTI-CLATHRIN HEAVY CHAIN MONOCLONAL ANTIBODY FOR INHIBITION OF TUMOR ANGIOGENESIS AND GROWTH AND APPLICATION THEREOF - A purified monoclonal antibody, or an. antigen-binding portion thereof, which specifically binds to human clathrin heavy chain (CHC) is disclosed. The antibody, or antigen-binding portion, thereof, exhibits at least one, two, three, four, five, six, seven, or all eight of the following properties: (a) specifically binds to pancreatic adenocarcinoma cells; (b) binding to the cell surface and cytosol of cancer cells and tumor blood vessels; (c) internalized by CHC-expressing cells; (d) inhibiting tumor growth, invasion ability, migration, and angiogenesis; (e) inducing apoptosis in cancer cells and human umbilical vein endothelial cells; (f) inhibiting tumor growth and tumor blood vessels in pancreatic cancer in vivo; (g) suppressing epidermal growth factor, transferrin, and VEGF internalizations by cancer cells; and (h) suppressing hypoxia-inducible factor-1α expression and vascular endothelial growth factor secretion. Methods for inhibiting tumor cell growth and/or angiogenesis, and detecting cancer in a subject is also disclosed. | 04-04-2013 |
Patent application number | Description | Published |
20130123183 | Anti-tumor Fibrillar Human Serum Albumin Methods and Compositions - Fibrillar human serum albumin was shown to be effective in the treatment of various types of cancers. Methods and compositions are disclosed for using fibrillar human serum albumin as a medicament to treat subjects having cancer. | 05-16-2013 |
20130126834 | ORGANIC LUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT APPARATUS - An organic luminescent material includes a host luminescent material and a guest luminescent material. The host luminescent material includes a compound represented by formula (1), | 05-23-2013 |
20130161199 | Production of Graphene - An apparatus for large-scale production of graphene and graphene oxide is provided. The apparatus includes a first electrode, a second electrode, an electrobath, a power supply, and a module for filtering and separating the graphene products. Large amounts of graphene and graphene oxide can be produced rapidly using electrochemical exfoliation. High-quality graphene and graphene oxide can be produced under the room temperature in a simple and cost-effective way. | 06-27-2013 |
20130185053 | Typing Candidate Generating Method for Enhancing Typing Efficiency - For relieving typing burdens caused by incorrect spellings, typing errors, unknown spellings, and characters with diacritical marks, and for enhancing a typing efficiency of a typist with some simplified techniques, several candidate generating methods are provided for assisting the typist to pick a candidate word from a list of generated candidate words, or for selecting a candidate word from said list of generated candidate words in an automatic-selection manner. A proper-designed user interface may also be utilized for implementing the candidate generating methods. | 07-18-2013 |
20130185823 | MESOPOROUS SILICA NANOPARTICLE-MEDIATED DELIVERY OF DNA INTO ARABIDOPSIS ROOT - Transient gene expression is a powerful tool for plant genomics studies. Recently, the use of nanomaterials has drawn great interest. Delivery with mesoporous silica nanoparticles (MSNs) has many advantages. We used surface-functionalized MSNs to deliver and express foreign DNA in | 07-18-2013 |
20130187042 | PERIODIC FIELD DIFFERENTIAL MOBILITY ANALYZER - A periodic field differential mobility analyzer apparatus for separating and identifying ionic analytes employs a series of elongated parallel channels, a pump, a first voltage providing an electric field E | 07-25-2013 |
20130188249 | OPTICAL MODULE AND MICROSCOPE - An optical module includes at least a carrying stage, at least an actuator unit and at least an optical assembly. The carrying stage has a first aperture. The actuator unit is disposed at one side of the carrying stage and has a second aperture. The optical assembly is connected with the actuator unit, and the actuator unit adjusts the position of the optical assembly. A radiated wave enters from one side of the optical module and passes through the first aperture, the second aperture and the optical assembly. A microscope with the optical module has compact size and is easily assembled and carried. The optical module and microscope can efficiently reduce the effect of ambient temperature variations so as to improve the measuring stability thereof. | 07-25-2013 |