Alessia
Alessia Ciccotelli, Vicenza (vi) IT
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20140054471 | DEVICE FOR SHAPING AN ELECTRON BEAM OF A MACHINE FOR INTRAOPERATIVE RADIATION THERAPY - The present invention concerns a device for shaping an electron beam of a machine for intraoperative radiation therapy (IORT—Intra Operative Radiation Therapy) using a tubular applicator ( | 02-27-2014 |
20150174430 | RADIATION DOSE CONTROL DEVICE FOR CONTROLLING AN ELECTRON BEAM PULSE DELIVERED DURING IORT - A radiation dose control device for controlling an electron beam pulse delivered during a therapy session of IORT (Intra-Operative Radiation Therapy), comprising a PWM system configured to provide an electron injection at a DC voltage at each pulse of an input electron beam (FE) sent to the input of an electronic gun (G) of a linear accelerator or linac (AL), so that the output electron beam (FU) exiting said linac (AL) is highly stable, and so that a variation of the radiation dose of said output electron beam (FU) results only from the variation of the delivery time of said input electron beam (FE); said dose variation of the output electron beam (FU) is thus directly proportional to said delivery time of the input electron beam (FE). | 06-25-2015 |
Alessia Covre, Tavagnacco (ud) IT
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20150374731 | DNA HYPOMETHYLATING AGENTS FOR CANCER THERAPY - The present invention relates to a method of treating and/or preventing cancer comprising administering a combination of an effective amount of a DNA hypomethylating agent and an effective amount of at least one immunomodulatory agent and/or optionally an effective amount of at least one targeted therapy agent. | 12-31-2015 |
Alessia Covre US
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20150374731 | DNA HYPOMETHYLATING AGENTS FOR CANCER THERAPY - The present invention relates to a method of treating and/or preventing cancer comprising administering a combination of an effective amount of a DNA hypomethylating agent and an effective amount of at least one immunomodulatory agent and/or optionally an effective amount of at least one targeted therapy agent. | 12-31-2015 |
Alessia Dessi, Quartu Sant'Elena IT
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20130143718 | APPARATUS, A SYSTEM AND A RELATING METHOD FOR LOCAL OR REMOTE REHABILITATION AND FUNCTIONAL EVALUATION OF THE HANDS - An apparatus for the local and/or remote rehabilitation and functional evaluation of the right and/or left hand of a user includes: a number of gym tools for the execution of hand exercises, each gym tool including a mechanical part, a sensor for the transformation of measured physical parameters into electrical signals; a user interface, configured to guide the user in the use of the gym tools, and providing feedbacks to the sequence of user actions; a first processing unit, configured to manage the apparatus functions, signal processing, storing and forwarding information on the measured physical parameters to at least one external device; a short-range communication module, configured to allow a real-time close-distance control of the apparatus; a wide-range communication module, configured to allow the connection to at least one long-distance tele-monitoring system. | 06-06-2013 |
Alessia Di Giancamillo, Milan (mi) IT
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20160106885 | COMPOSITE SCAFFOLD FOR TISSUE REPAIR - A synthetic composite material for tissue repair is disclosed which includes a first layer having an organic material and having side walls and external surface; and a second porous layer comprising an inorganic material and having side walls; wherein the first layer is in direct contact with the second layer and wherein the side walls of the first layer and the side walls of the second layer are coated with a third layer of the organic material. | 04-21-2016 |
Alessia Fornoni, Coral Gables, FL US
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20130202601 | ASSAYS, METHODS AND KITS FOR PREDICTING RENAL DISEASE AND PERSONALIZED TREATMENT STRATEGIES - Assays, methods and kits for predicting a subject's (e.g., human) risk of primary glomerulopathy, secondary glomerulopathy or recurrence (e.g., post-transplant recurrence) of any glomerular disease include examining cells for the presence or absence of cytoskeletal disruptions or rearrangements and examining cells for modulation of expression and/or activity of markers such as SMPDL-3b. Assays for predicting if a diabetic subject will develop kidney disease or a patient with FSGS will develop recurrent disease after transplant also include examining cells for the presence or absence of cytoskeletal disruptions or rearrangements and examining cells for modulation of expression and/or activity of markers such as SMPDL-3b. Also described herein are compositions and methods for treating and preventing the afore-mentioned disorders. | 08-08-2013 |
20140302065 | SOLUBLE UROKINASE RECEPTOR (SUPAR) IN DIABETIC KIDNEY DISEASE - Methods and compositions are provided for diagnosing and treating a diabetic kidney disease (DKD) in an individual. In aspects of the methods, the levels of soluble circulating urokinase receptor (suPAR) in the blood are measured to predict a DKD, diagnose a DKD, or provide a prognosis pertaining to a DKD. In addition, reagents, devices and kits thereof that find use in practicing the subject methods are provided. | 10-09-2014 |
Alessia Fornoni, Miami, FL US
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20150065457 | METHOD OF USING CYCLODEXTRIN - Described are methods for using cyclodextrin to treat, inhibit, prevent, ameliorate, or cure diabetes or conditions relating to diabetes. | 03-05-2015 |
Alessia Ligresti, Pozzuoli IT
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20130059018 | PHYTOCANNABINOIDS IN THE TREATMENT OF CANCER - This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon. | 03-07-2013 |
20150086653 | PHYTOCANNABINOIDS IN THE TREATMENT OF CANCER - This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon. | 03-26-2015 |
Alessia Millemaggi, Cambridge GB
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20150051199 | PHARMACEUTICAL COMPOUNDS - The invention provides compounds that are useful in the treatment of hepatitis C virus (HCV) infections. The compounds have the formula (1): | 02-19-2015 |
20150266873 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY - The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. | 09-24-2015 |
Alessia Montagnoli, Milan IT
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20120157454 | ISOQUINOLIN-1 (2H) -ONE DERIVATIVES AS PARP-1 INHIBITORS - There are provided substituted isoquinolin-1(2H)-one derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of the present invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. A screening method for the identification of compounds capable of binding several PARP proteins, as well the probes used in such method, are further objects of the invention. | 06-21-2012 |
20120276093 | THERAPEUTIC COMBINATION COMPRISING A CDC7 INHIBITOR AND AN ANTI-NEOPLASTIC AGENT - The present invention provides a therapeutic combination comprising (a) a compound of formula (I) as set forth in the specification and (b) one or more antineoplastic agents selected from the group consisting of an alkylating or alkylating-like agent, an antimetabolite agent, a topoisomerase I inhibitor, a topoisomerase 11 inhibitor, an inhibitor of a growth factor or of a growth factor receptor, an antimitotic agent, a proteasome inhibitor, an inhibitor of an anti-apoptotic protein and an antibody directed against a cell surface protein, wherein the active ingredients are present in each case in lice form or in the form of a pharmaceutically acceptable salt or any hydrate thereof. | 11-01-2012 |
20130129841 | THERAPEUTIC COMBINATION COMPRISING A PARP-1 INHIBITOR AND AN ANTI-NEOPLASTIC AGENT - The present invention provides a therapeutic combination comprising (a) a compound of formula (I) as set forth in the specification and (b) one or more antineoplastic agents selected from the group consisting of an alkylating or alkylating-like agent, an antimetabolite agent, a topoisomerase I inhibitor, a topoisomerase II inhibitor, an antimitotic agent and radiation wherein the active ingredients are present in each case in free form or in the form of a pharmaceutically acceptable salt or any hydrate thereof. | 05-23-2013 |
20140045846 | ISOQUINOLIN-1(2H)-ONE DERIVATIVES AS PARP-1 INHIBITORS - There are provided substituted isoquinolin-1(2H)-one derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of the present invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. A screening method for the identification of compounds capable of binding several PARP proteins, as well the probes used in such method, are further objects of the invention. | 02-13-2014 |
Alessia Pasquazi, Roma IT
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20130156051 | STABLE MODE-LOCKED LASER FOR HIGH REPETITION RATE OPERATION - A laser system comprises a high-Q nonlinear optical resonator, a cavity comprising an amplifying element and a dispersive element, an optical delay line adapted to tune the length of the cavity, and a large pass-band filter adapted to tune the cavity's central oscillation wavelength, the nonlinear optical resonator being selected with a linewidth (LW | 06-20-2013 |
Alessia Portieri, Cambridge GB
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20100108889 | METHOD AND APPARATUS FOR IMAGING AN LCD USING TERAHERTZ TIME DOMAIN SPECTROSCOPY - A method configured to investigate an LCD structure, the method comprising: irradiating an LCD structure with pulsed radiation having at least one frequency in the range from 40G Hz to 100 THz; detecting radiation which has been transmitted through or reflected by the structure; determining information about the structure by measuring a quantity at least related to the amplitude of the detected radiation. | 05-06-2010 |
Alessia Salmeri, Torino IT
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20150332008 | Method and System for Providing a Telecare Service - A method is disclosed for providing a telecare service to a patient. According to the method, at least one sensor installed in a domestic environment of the patient detects a datum relating to either the domestic environment or an interaction between patient and domestic environment. Based on the detected datum, an anomaly in the domestic environment or in the interaction between patient and domestic environment is detected. Then, a predefined question uniquely associated with the detected anomaly is selected for generating a questionnaire to be submitted to the patient, with the purpose of determining the cause of the detected anomaly. Based on the patient's reply it is determined if the detected anomaly is a false anomaly and, in the affirmative, the predefined question associated to such false anomaly is excluded from the next questionnaire(s), even if the anomaly persists. | 11-19-2015 |
Alessia Santoprete, Pomezia IT
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20120165503 | OXYNTOMODULIN ANALOGS - Peptide analogs of oxyntomodulin (OXM, glucagon-37), which have been modified to be resistant to cleavage and inactivation by dipeptidyl peptidase IV (DPP-IV) and to increase in vivo half-life of the peptide analog while enabling the peptide analog to act as a dual GLP-1/glucagon receptor (GCGR) agonistm are described. The peptide analogs are useful for treatment of metabolic disorders such as diabetes and obesity. | 06-28-2012 |
Alessia Scire, Dresden DE
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20140097521 | Silicon on Nothing Devices and Methods of Formation Thereof - In accordance with an embodiment of the present invention, a method of forming a semiconductor device includes forming a first cavity within a substrate. The first cavity is disposed under a portion of the substrate. The method further includes forming a first pillar within the first cavity to support the portion of the substrate. | 04-10-2014 |
20140353852 | METHOD FOR PROCESSING A CARRIER AND A CARRIER - A method for processing a carrier may include forming at least one recess structure at least one of over and in the carrier; and annealing the at least one recess structure such that at least one hollow chamber is formed by material of the at least one recess structure, wherein the at least one hollow chamber may form an optical alignment structure. | 12-04-2014 |
20150115226 | OPTOELECTRONIC COMPONENT, A METHOD FOR MANUFACTURING AN OPTOELECTRONIC COMPONENT, AND A METHOD FOR PROCESSING A CARRIER - According to various embodiments, an optoelectronic component may be provided, the optoelectronic component including: an electrode structure disposed at least one of over and in a carrier; and a grating structure disposed over the electrode structure, the grating structure including at least a first region and a second region, wherein the first region of the grating structure includes amorphous silicon; and wherein the second region of the grating structure includes a material having a refractive index different from the refractive index of the amorphous silicon. | 04-30-2015 |
20150147839 | METHOD FOR MANUFACTURING A SEMICONDUCTOR DEVICE - A method for manufacturing a semiconductor device may include: forming a metal layer structure over a semiconductor workpiece; forming a first layer over the metal layer structure, the first layer including a first material; forming at least one opening in the first layer and the metal layer structure; depositing a second layer to fill the at least one opening and at least partially cover a surface of the first layer facing away from the metal layer structure, the second layer including a second material that is different from the first material; removing the second layer from at least the surface of the first layer facing away from the metal layer structure; and removing the first layer. | 05-28-2015 |
20150163915 | ELECTRONIC DEVICE, A METHOD FOR MANUFACTURING AN ELECTRONIC DEVICE, AND A METHOD FOR OPERATING AN ELECTRONIC DEVICE - According to various embodiments, an electronic device may include a carrier including at least a first region and a second region being laterally adjacent to each other; an electrically insulating structure arranged in the first region of the carrier, wherein the second region of the carrier is free of the electrically insulating structure; a first electronic component arranged in the first region of the carrier over the electrically insulating structure; a second electronic component arranged in the second region of the carrier; wherein the electrically insulating structure includes one or more hollow chambers, wherein the sidewalls of the one or more hollow chambers are covered with an electrically insulating material. | 06-11-2015 |
20150318166 | WAFER, A METHOD FOR PROCESSING A WAFER, AND A METHOD FOR PROCESSING A CARRIER - According to various embodiments, a method for processing a wafer may include: forming at least one hollow chamber and a support structure within the wafer, the at least one hollow chamber defining a cap region of the carrier located above the at least one hollow chamber and a bottom region of the carrier located below the at least one hollow chamber and an edge region surrounding the cap region of the carrier, wherein a surface area of the cap region is greater than a surface area of the edge region, and wherein the cap region is connected to the bottom region by the support structure; removing the cap region in one piece from the bottom region and the edge region. | 11-05-2015 |
20150340268 | Silicon on Nothing Devices and Methods of Formation Thereof - In accordance with an embodiment of the present invention, a method of forming a semiconductor device includes forming a first cavity within a substrate. The first cavity is disposed under a portion of the substrate. The method further includes forming a first pillar within the first cavity to support the portion of the substrate. | 11-26-2015 |
20160079182 | METHOD FOR PROCESSING A CARRIER AND A CARRIER - A method for processing a carrier may include forming at least one recess structure at least one of over and in the carrier; and annealing the at least one recess structure such that at least one hollow chamber is formed by material of the at least one recess structure, wherein the at least one hollow chamber may form an optical alignment structure. | 03-17-2016 |
Alessia Terrida, Montebelluna (tv) IT
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20120066845 | DEVICE FOR THE REPLACEMENT OF THE REMOVABLE HEEL, PROVIDED WITH PULLING ENGAGEMENT DEVICES, IN A SHOE WITH REMOVABLE HEEL - Device for the replacement of the removable heel provided with pulling engagement devices in a shoe with removable heel including, associated to the heel-holding sole, a first engagement plate with hooking seats provided with guide slot and guide opening for the engagement of the head of a pulling pin as well as of a first engagement wall and a second engagement wall among which the guide opening is arranged, being the first engagement plate provided with an engagement pin and at least one guide seat, being a second engagement plate joined to the upper part of the removable heel and equipped with pulling pins, provided with head and spring, being the second engagement plate, for the association to the first engagement plate, provided with at least one small peg, through seats and through opening. | 03-22-2012 |
Alessia Tuninetti, Carmagnola IT
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20130080028 | METHOD FOR OPERATING AN INTERNAL COMBUSTION ENGINE - An exemplary embodiment of the present disclosure provides a method for operating an internal combustion engine comprising: monitoring a value of a temperature parameter of a diesel particulate filter of the internal combustion engine; monitoring a value of an operating parameter of the internal combustion engine indicative of an engine load; using the monitored value of the engine load parameter to determine a threshold value of the diesel particulate filter temperature parameter; testing whether the monitored value of the diesel particulate filter temperature parameter exceeds the determined threshold value thereof; and diagnosing that the diesel particulate filter is overheated if the test returns positive. | 03-28-2013 |
Alessia Tuninetti, Piemonte IT
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20110185706 | METHOD FOR MANAGING THE REGENERATION OF A DIESEL PARTICULATE FILTER (DPF) IN A DIESEL ENGINE SYSTEM - A method is provided for managing the regeneration of a Diesel Particulate Filter (DPF) in a Diesel engine system. The engine having an intake and an exhaust line and being configured to after-inject or post-inject quantities of fuel into a combustion chamber for raising the temperature of the engine exhaust gas. The engine including in the exhaust line, but not limited to, a Diesel Particulate Filter (DPF). The method including, but not limited to identifying a faulty condition of the engine system and, in case that such faulty condition is not critical, measuring the intake air charge and, in case such intake air charge is acceptable, and performing a regeneration process for said Diesel Particulate Filter (DPF). | 08-04-2011 |
20120011829 | METHOD TO OPERATE A DIESEL PARTICULATE FILTER - A method is provided to operate a diesel particulate filter of a Diesel engine equipped with a soot-sensor located in an outlet of the diesel particulate filter, the soot-sensor operating according to a succession of soot loading phases mutually separated by a regeneration phase. The method includes, but is not limited to setting a borderline value of the efficiency of the diesel particulate filter, resetting a value of a counter, during a regeneration phase of the soot-sensor, this value representing a soot loading level of the soot-sensor, iteratively increasing the value of this counter, during a next soot loading phase of the soot-sensor, at least until the value reaches a predetermined threshold value of the counter, and detecting an unsuited efficiency of the diesel particulate filter, if a next regeneration phase of the soot-sensor begins when the value of the counter is below the predetermined threshold value of the counter. | 01-19-2012 |
Alessia Vador, Zelarino Venezia IT
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20120129884 | PHOTOCHEMOTHERAPEUTIC HETEROCYCLIC AGENTS HAVING ANTIPROLIFERATIVE AND ANTINEOPLASTIC ACTIVITY - The present invention concerns the synthesis of new analogs of angelicins, pyrrolo [3,2-h]quinoline, for the treatment of pathologies having hyperproliferative character included those having neoplastic nature. The treatment is based on the combined action of pyrrolo [3,2-h]quinolines and UV-A light, through a clinical approach defined as PUVA (psoralen-UVA light). The most important feature of these compounds is that they exert their remarkable photoxicity without any DNA damage, which is the main origin of the side effects of the PUVA therapy. | 05-24-2012 |