Arjan Laurens
Arjan Laurens Van Wuijckhuijse, Hendrik-Ido-Ambacht NL
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20110204220 | Method and Apparatus for Identification of Biological Material - Biological material is detected in a sample using a MALDI-MS technique (Matrix Assisted Laser Desorption and Ionization-Mass Spectroscopy). A liquid comprising the sample and a MALDI matrix material is prepared and used to form a continuous stream of the liquid. The stream is separated into successive parts to form drops, which are launched into flight, or the stream is launched into flight and then separated into drops. Drop forming techniques may be used that are known from ink jet printers. Material from the drops is ionized while in flight. Mass spectra from the ionized material of respective drops are measured. Preferably, before the drops are formed the liquid is diluted to a level where the majority of drops at most one micro-organism is present per drop. | 08-25-2011 |
Arjan Laurens Van Wuijckhuijse, Leiden NL
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20150066377 | Method for Classification of a Sample on the Basis of Spectral Data, Method for Creating a Database and Method for Using this Database, and Corresponding Computer Program, Data Storage Medium and System - The invention relates to a method for classification of a sample on the basis of spectral data, a method for creating a database and a method for using this database, and corresponding computer program, data storage medium and system. The method comprises: a) obtaining at least two sets of first spectra for use as reference spectra, each set comprising spectra of reference samples belonging to the same class; b) determining for each of the reference spectra the value of the same at least one quantity related to a spectral feature; c) associating a probability to different values of the quantity on the basis of the determined values; d) obtaining a spectrum from the sample and determining the value of the same at least one quantity of this spectrum; and e) calculating on the basis of the probabilities and the value of the quantity for the obtained spectrum for each of said at least two classes a probability that the sample belongs to that class. | 03-05-2015 |
Arjan Laurens Wuijckhuijse, Zwijndrecht NL
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20120018628 | MATRIX FOR REAL-TIME AEROSOL MASS SPECTROMETRY OF ATMOSPHERIC AEROSOLS AND REAL-TIME AEROSOL MALDI MS METHOD - Matrix for real-time aerosol mass spectrometry of atmospheric aerosols and real-time aerosol MALDI MS method Abstract The invention is directed to a matrix material for MALDI mass spectrometry, to a matrix composition for MALDI mass spectrometry, in particular for aerosol MALDI mass spectrometry, to a MALDI mass spectrometry method, in particular an aerosol MALDI mass spectrometry method, to the use of a specific compound as a MALDI matrix material, and to the use of a MALDI matrix composition in a gas phase coating method. The matrix material of the invention comprises a 2-mercapto-4,5-dialkylthiazole according to formula (I), wherein X is chosen from S, O or N, and wherein R | 01-26-2012 |