Patent application number | Description | Published |
20140179680 | Substituted Imidazopyridines as HDM2 Inhibitors - The present invention provides substituted imidazopyridines as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same. | 06-26-2014 |
20140357618 | SUBSTITUTED IMIDAZOPYRIDINES AS HDM2 INHIBITORS - The present invention provides substituted imidazopyridines as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same. | 12-04-2014 |
20150191461 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS - The present invention provides novel pyrazole derivatives of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer. | 07-09-2015 |
20150368247 | 2,6,7 SUBSTITUTED PURINES AS HDM2 INHIBITORS - The present invention provides 2,6,7 substituted purines as described herein or a pharmaceutically acceptable salt thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same. | 12-24-2015 |
Patent application number | Description | Published |
20150083974 | METHOD FOR PREPARING SILVER-BASED ELECTRICAL CONTACT MATERIAL - The present invention relates to a new method for preparing a silver-based electrical contact material, comprising following steps of: (a) providing a carbonaceous mesophase solution; (b) adding a silver source into the carbonaceous mesophase solution and stirring to obtain a compound; (c) removing a solvent from the compound to obtain a solid; (d) performing a heat treatment on the solid, and obtaining a silver-based electrical contact material. The silver source is silver powder prepared by means of a chemical method. By means of the method, a uniform carbonaceous coating on silver is implemented, the silver is uniformly distributed in a nanometer scale, and a diamond is generated in situ of a material after being sintered. The silver-based electrical contact material processed by means of this method shows an excellent mechanical wear resistance and electrical property. | 03-26-2015 |
20150128848 | Method of Preparing Nanostructured Single Crystal Silver - A method of preparing nanostructured single crystal silver, comprising placing a high-conductive molded porous active carbon containing chloride ions, which has been reductively treated, into a silver-containing precursor solution. After several hours at room temperature, the nanostructured single crystal silver grows on the surface of the active carbon. The silver-containing precursors and appropriate amount of chlorine provide a crystal nucleus and a slow stable crystal growth environment which are required for single crystal silver growth, and said nanostructured silver single crystals could be obtained with various morphologies by controlling the concentration of the silver-containing precursor solution and the growth time. The method of the invention is an environmentally friendly synthesis method with the nanostructured single crystal silver grows on the surface of the molded porous active carbon at room temperature, which is pollution-free and does not need any additives; the single crystal could be obtained in high yield and high purity, and can be separated from the molded porous active carbon easily, the grown silver falls off naturally and the active carbon is renewable through sonication with absolute ethanol or alkaline solutions; and the obtained single crystal silver is characterized by having high mechanical strength, good conductivity and less crystal defects. | 05-14-2015 |
20150132502 | METHOD FOR PREPARING DIAMOND CARBON MEMBRANE ON SURFACE OF STAINLESS STEEL - The present invention relates to a method for preparing a diamond carbon membrane on a surface of stainless steel, including: immersing the pretreated stainless steel into a solution of a biomass-derived carbonaceous mesophase in ethanol for several minutes, prior to taking out and air drying; or alternatively, spraying the solution of the biomass-derived carbonaceous mesophase in ethanol onto the stainless steel surface, to provide a layer of the biomass-derived carbonaceous mesophase film adhered on the stainless steel surface upon full volatilization of the solution on the surface; and then carrying out thermal treatment under a hydrogen atmosphere, to prepare the diamond carbon membrane on the stainless steel surface. By the preparation process, which is convenient and easy in operation, and low in cost, the diamond carbon membrane can be made on the stainless steel substrate in a complicated shape, which has a high level of diamond phase and is uniform, dense, and firm in bonding with the stainless steel substrate, leading to improvement of corrosion resistance, wearability, rigidity and high temperature resistance of the stainless steel, and being worth expanding in practical application. | 05-14-2015 |
20150133568 | METHOD FOR PREPARING GRAPHENE FROM BIOMASS-DERIVED CARBONACEOUS MESOPHASE - The present invention relates to a method for preparing graphene from a biomass-derived carbonaceous mesophase, which includes: soaking a base substance into an ethanol solution of a biomass-derived carbonaceous mesophase; after a certain period of time, taking out and drying the base substance, a layer of biomass-derived carbonaceous mesophase film being attached to the surface of the base substance; subjecting the base substance to a heat treatment under the protection of a hydrogen atmosphere, then a stacked graphene film was formed on the surface of the base substance; and further subjecting the base substance to ultrasonic dispersion in an alcohol solvent to separate the graphene film and the base substance, then a graphene alcosol was formed. The preparation process of the present invention is easy to implement. The raw material biomass-derived carbonaceous mesophase has abundant sources and is low in cost. The preparation process has low energy consumption, and is applicable to mass production. The obtained graphene film and graphene alcosol can be used in solar cells, nano-electronic devices, sensors, and so on, and have broad market prospects. | 05-14-2015 |