Patent application number | Description | Published |
20100291683 | Modified Antigen Presenting Cells and Methods of Use - The invention provides compositions comprising and methods of using antigen presenting cells into which has been introduced at least a first nucleotide sequence that encodes calnexin, wherein expression of calnexin in the antigen presenting cell increases the antigen presenting cell's ability to activate a T cell response. | 11-18-2010 |
20100316603 | Combination Immunogene Therapy - The present invention provides to immunogene therapy protocols for the treatment of tumors. In particular, the present invention provides combinations of immune-modulating proteins that induce systemic immunity against tumors. In addition, the present invention provides humanized animal models suitable for the evaluation of anti-human tumor immunity and permit the identification of combinations of immune-modulating genes which when delivered to human tumor cells induce an effective anti-tumor response, including a systemic anti-tumor response. | 12-16-2010 |
20110236363 | SYSTEM AND METHOD FOR PRODUCING T CELLS - Disclosed herein is a system and method for producing T cells from stem cell populations. Specifically exemplified herein is a culture system and method that produces CD4 cells and/or T cell subtypes from a CD4 lineage using a sample of hematopoietic stem cells. Adult hematopoietic precursor/stem cells (HPC) are progenitors to all lineages of immune cells. There has been limited success in generating functional CD4 T cells with this convenient culture system. Also disclosed herein is a novel stromal cell line expressing DL1, interleukin-7 (IL-7), and FMS-like tyrosine kinase 3 ligand (Flt3-L). This improved culture system can greatly facilitate the study of late T cell development and enables immunotherapeutic applications. | 09-29-2011 |
20130330310 | EX VIVO DEVELOPMENT, EXPANSION AND IN VIVO ANALYSIS OF A NOVEL LINEAGE OF DENDRITIC CELLS - Disclosed herein are new methods of producing a novel line of dendritic cells. The method comprises subjecting a sample of hematopoietic stem/precursor cells to a first feeder culture system that is supplemented with a first set of factors and a second feeder culture system supplemented with a second group of factors. The disclosure also pertains to new cell types that may be used as cancer immunotherapy. | 12-12-2013 |
Patent application number | Description | Published |
20100051540 | Retention/Detention Pond And Green Roof Passive Nutrient Removal Material Mixes - Materials, compositions, substances and methods and systems for stormwater treatment in wet ponds, dry ponds and a green roof system. A first embodiment provides in-situ treatment unit within the retention pond by withdrawing the stored stormwater to circulate the stored stormwater into the in-situ treatment unit to sorb nitrogen from the stored stormwater. A second embodiment provides uses a riprap apron, a perforated riser located at the bottom of the riprap apron and a goetextile media encased in a sorption media jacket around the perforated riser. A third embodiment provides a green roof stormwater treatment system that includes protection for waterproofing and insulating the roof, a pollution control media layer for filtration and sorption of solids and dissolved materials found in stormwater, a growing media for growing vegetation, and a cistern to store the runoff stormwater between irrigation events. The green roof system includes recycling runoff stormwater by irrigating the green roof with the stored stormwater. | 03-04-2010 |
20100059437 | Passive Underground Drainfield For Septic Tank Nutrient Removal Using Functionalized Green Filtration Media - Methods, systems and compositions for a green sorption media for bioretention soil amendments in drainfields for on-site waste water systems filled with the green sorption media to foster an anaerobic or anoxic environment saturated. The green sorption media includes one or more recycled materials, including tire crumb, sawdust, orange peel, coconut husks, leaf compost, oyster shell, soy bean hulls and one or more naturally occurring materials including peat, sands, zeolites, and clay. The wastewater filtration system for a passive drainfield includes the green sorption material mixture, a cell including baffled compartments and a riser, the cell filled with green sorption material mixture to provide an alternating cycle of aerobic and anoxic environments, an influent distribution system to distribute the influent over the cell, and a piping system arranged for dosing the cell to sustain the functionality of the green sorption material mixture to remove nutrient content in wastewater. | 03-11-2010 |
20100062933 | Functionalized green filtration media for passive underground drainfield for septic tank nutrient removal - Methods, systems and compositions for a green sorption media for bioretention soil amendments in drainfields for on-site waste water systems filled with the green sorption media to foster an anaerobic or anoxic environment saturated. The green sorption media includes one or more recycled materials, including tire crumb, sawdust, orange peel, coconut husks, leaf compost, oyster shell, soy bean hulls and one or more naturally occurring materials including peat, sands, zeolites, and clay. The wastewater filtration system for a passive drainfield includes the green sorption material mixture, a cell including baffled compartments and a riser, the cell filled with green sorption material mixture to provide an alternating cycle of aerobic and anoxic environments, an influent distribution system to distribute the influent over the cell, and a piping system arranged for dosing the cell to sustain the functionality of the green sorption material mixture to remove nutrient content in wastewater. | 03-11-2010 |
Patent application number | Description | Published |
20100142454 | SYSTEM AND METHOD FOR AUTOMATED OPTIMIZATION OF SPECTRUM ALLOCATION - The present disclosure describes systems and methods that facilitate the allocation of spectrum for wireless communications. A database may be maintained that includes spectrum that has been offered by spectrum holders for use by spectrum users. Portions of the offered spectrum that have been allocated to spectrum users may be identified, the remainder of the offered spectrum being unallocated spectrum. A request specifying aspects of desired spectrum may be received from a user. A lack of available spectrum from the offered spectrum that fulfills the specified aspects in the request may be identified. Unallocated spectrum from a corresponding spectrum offer may be apportioned to fulfill the request with unallocated spectrum that matches the time duration and the geographic area aspects of the request and that has a frequency range that is shifted from the frequency range of the request for at least a portion of the time duration. | 06-10-2010 |
20100145745 | SYSTEM AND METHOD FOR TRANSFERRING SPECTRUM USE RIGHTS - The present disclosure describes systems and methods that facilitate the transfer rights associated with spectrum between parties. Access to spectrum for wireless communications may be transferred from a spectrum holder to a spectrum user while minimizing their role in submitting regulatory agency compliance filings. As a result, parties may transfer spectrum with relative ease, with faster transaction time and lower expense. This leads to more efficient use of the spectrum. | 06-10-2010 |
20100145862 | AUTOMATED SPECTRUM EXCHANGE SYSTEM AND METHOD - The present disclosure describes systems and methods that facilitate the transfer of rights associated with spectrum between parties by providing an automated spectrum exchange in which spectrum is a tradable commodity. In one embodiment, data is received from a spectrum holder that defines a spectrum offering by frequency, time, and geographic area to identify available spectrum from the holder. A spectrum query that defines aspects of spectrum being sought by a spectrum user is also received and matched to one or more spectrum offerings. A transactional process is hosted by receiving a bid or rebid from the spectrum user for a matched spectrum offering and receiving a counteroffer from the spectrum holder that posted the matched spectrum offering. Each spectrum offering, bid, rebid, and counteroffer specifies price, frequency, time, and geographic area information in a standardized format. As a result, the automated spectrum exchange allows parties to market, locate, and transfer spectrum use rights with relative ease, faster transaction time, and lower expense. | 06-10-2010 |
Patent application number | Description | Published |
20090310575 | Keep alive timeslots in a heterogeneous MAC protocol to track handsets in a wireless network - This disclosure describes a new keep alive timeslots based method to track registered handsets for a MAC protocol that combines contention-free and contention-based MAC protocols into a heterogeneous MAC protocol used for forwarding VoIP traffic in VoIP systems on wireless networks using multiple base stations thus allowing for transmission of high bit-rate data to multiple users over wired and wireless means. | 12-17-2009 |
20100014503 | Method for extending a heterogeneous MAC protocol to multi-channel systems - An extension to a heterogeneous MAC protocol that makes provisions for multi-frequency system architecture is described. A new frame structure for a multi-frequency xMAX system is introduced. Multi-frequency xMAX system is an extension of a single-channel xMAX system, where the available bandwidth is split into multiple channels to provide additional capacity and range. The new frame structure is followed by all channels and is designed to fulfill the requirements of multiple frequency operation. The new frame structure incorporates features that allow the handset to leverage the advantages of multiple frequency channels, especially in the event of interference. Also, a new mechanism to reduce the power consumption in the handset is discussed that significantly reduces the number of unnecessary receive operations at the handset. | 01-21-2010 |
20100124202 | RTP voice packets for base station hand-off in mobile IP telephony - In wireless networks where the goal is to support a large number of VOIP based cellular calls, large overhead headers in RTP voice packets are not acceptable. In wireless networks where multiple base stations are deployed, handsets may handoff from one base station to the other while in a voice call creating a large overhead. This disclosure describes an efficient way to extend a header compression algorithm and lower the overhead when the handset is in a voice call and hands off from one base station to another. | 05-20-2010 |
20110003604 | Dynamic pattern elimination based compression method for text-based signaling protocols - This disclosure describes a dynamic pattern elimination compression method to eliminate redundant patterns, the content of which is not known a priori, by identifying the candidate dynamic patterns and marking them, then checking to see if there are any duplicate occurrences within the entire message by searching for markers, if a marker is found, checking to see if the pattern occurred before, if not, assigning a unique variable to the pattern, if so replacing the pattern with the variable that was assigned for this pattern, and if a pattern is found only once, removing the variable assigned to it. | 01-06-2011 |
Patent application number | Description | Published |
20140098528 | LED RETROFIT LAMP - An LED retrofit lamp which has one end which is configured to engage a standard light bulb socket, such as an E26 or E39 socket. The other end provides a plurality of LED's—a center section of LED's pointing downward, and a plurality of LED's going around a perimeter of the center section, generally pointing outward. Preferably, the LED retrofit lamp | 04-10-2014 |
20140098568 | LED RETROFIT LAMP - An LED retrofit lamp which has one end which is configured to engage a standard light bulb socket, such as an E26 or E39 socket. The other end provides a plurality of LED's—a center section of LED's pointing downward, and a plurality of LED's going around a perimeter of the center section, generally pointing outward. Preferably, the LED retrofit lamp 10 includes circuitry which is configured to take the voltage received from the light bulb socket, and use that voltage to drive the LED's as well as, preferably, a fan which tends to keep the LED retrofit lamp within prescribed temperature tolerances. Preferably, a protective shield, such as a plastic protective shield, covers and protects the LED's. Furthermore, preferably the LED retrofit lamp includes louvers which allow the fan inside to grab air from the outside, and allows the hot air to escape. Preferably, the LED retrofit lamp is generally lightweight. | 04-10-2014 |