Patent application number | Description | Published |
20100040710 | Stimulation of the synthesis and of the activity of an isoform of lysyl oxidase-like LOXL for stimulating the formation of elastic fibers. - The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (lysyl oxidase-like) isoform. | 02-18-2010 |
20110014175 | STIMULATION OF THE SYNTHESIS OF THE ACTIVITY OF AN ISOFORM OF LYSL OXIDASE-LIKE LOXL FOR STIMULATING THE FORMATION OF ELASTIC FIBRES - The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (lysyl oxidase-like) isoform. | 01-20-2011 |
20110223264 | Substancefor Restoring Normal Co-expression and Interaction Between the LOX and NRAGE Proteins - The invention relates to a substance for restoring normal co-expression and interaction between the LOX and NRAGE proteins. | 09-15-2011 |
20120225141 | SUBSTANCE FOR RESTORING NORMAL CO-EXPRESSION AND INTERACTION BETWEEN THE LOX AND NRAGE PROTEINS - The disclosed substance restores normal co-expression and interaction between the LOX and NRAGE proteins. Particularly, an effective amount of the substance that modulates the expression and/or activity of LOX of SEQ ID NO: 1 and/or that modulates the expression and/or activity of NRAGE of SEQ ID NO: 2, may be used for the manufacture of a composition for modulating the interaction between the LOX and NRAGE proteins to regulate the balance between the cellular phenomena of proliferation, differentiation and apoptosis, particularly in cases where the balance between these phenomena is disturbed, and especially in cases where the interaction between LOX and NRAGE is absent or altered. The invention makes it possible especially to treat and/or prevent skin ageing, lichen planus, graft-versus-host reaction (GVH), eczema, psoriasis and a cancer, particularly an epithelial cancer and more particularly a cutaneous epithelial cancer of basocellular or spinocellular type. | 09-06-2012 |
20130011902 | STIMULATION OF THE SYNTHESIS OF THE ACTIVITY OF AN ISOFORM OF LYSYL OXIDASE-LIKE LOXL FOR STIMULATING THE FORMATION OF ELASTIC FIBERS - The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (lysyl oxidase-like) isoform. The invention relates notably to a method of identifying an active principle which stimulates the formation of elastic fibers. The aim of the invention is mainly to provide such a method of identification so as to provide compositions which enable stimulating the formation of elastic fibers. | 01-10-2013 |
Patent application number | Description | Published |
20110123636 | MICELLIC ASSEMBLIES - Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instances, micellic assemblies provided herein are pH sensitive particles. | 05-26-2011 |
20110129921 | TARGETED POLYMER BIOCONJUGATES - Polymer bioconjugate having a RNAi agent covalently coupled to the alpha or omega end of a pH-dependent membrane-destabilizing polymer. | 06-02-2011 |
20110142951 | MICELLES FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS - Composition comprising a polymeric micelle and an associated polynucleotide. | 06-16-2011 |
20110143435 | POLYMERIC CARRIER - Provided herein are polymeric carriers suitable for the delivery of polynucleotides (e.g. oligonucleotides) and/or other therapeutic agents into a living cell. | 06-16-2011 |
20110281934 | MICELLES OF HYDROPHILICALLY SHIELDED MEMBRANE-DESTABILIZING COPOLYMERS - Provided herein are micelles comprising a plurality of copolymers. In certain instances, micelles provided herein are pH sensitive particles. | 11-17-2011 |
20110286957 | MULTIBLOCK COPOLYMERS - Provided herein are multiblock copolymers, as well as micelles and therapeutic compositions thereof. | 11-24-2011 |
20120021514 | HETEROGENEOUS POLYMERIC MICELLES FOR INTRACELLULAR DELIVERY - Compositions comprising a heterogeneous polymeric micelle and an agent (e.g., a polynucleotide) associated with the micelle are disclosed, together with methods for intracellular delivery of such agent. | 01-26-2012 |
20130011362 | TARGETING MONOMERS AND POLYMERS HAVING TARGETING BLOCKS - Provided herein are monomers incorporating folate or other targeting agent, polymers prepared therefrom, polymers prepared therefrom having a therapeutic agent covalently coupled thereto, as well as micelles and therapeutic compositions thereof. | 01-10-2013 |
20130017167 | HYDROPHOBIC BLOCK CONJUGATED THERAPEUTIC AGENTS - Provided herein are polymers having a therapeutic agent covalently coupled to a hydrophobic block thereof, as well as micelles and therapeutic compositions thereof. | 01-17-2013 |