Collinson
Albert Collinson, Marlborough, MA US
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20120271033 | HIGH AFFINITY ADAPTOR MOLECULES FOR REDIRECTING ANTIBODY SPECIFITY - Disclosed are methods for identifying high affinity adaptor molecules that bind to both a circulating antibody and a target molecule and redirect the specificity of the circulating antibody to the target molecule. Exemplary high affinity adaptor molecules are also provided. | 10-25-2012 |
20140155579 | DUAL SPECIFICITY ANTIBODIES AND METHODS OF MAKING AND USING - Antibodies having dual specificity for two different but structurally related antigens are provided. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have dual specificity for IL-1α and IL-1β and neutralize IL-1α and IL-1β activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting two different but structurally related antigens (e.g., IL-1α and IL-β) and for inhibiting the activity of the antigens, e.g., in a human subject suffering from a disorder in which IL-1α and/or IL-1β activity is detrimental. | 06-05-2014 |
20140378666 | DUAL SPECIFICITY ANTIBODIES AND METHODS OF MAKING AND USING - Antibodies having dual specificity for two different but structurally related antigens are provided. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have dual specificity for IL-1α and IL-1β and neutralize IL-1α and IL-1β activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting two different but structurally related antigens (e.g., IL-1α and IL-1β) and for inhibiting the activity of the antigens, e.g., in a human subject suffering from a disorder in which IL-1α and/or IL-1β activity is detrimental. | 12-25-2014 |
20150175694 | DUAL SPECIFICITY ANTIBODIES AND METHODS OF MAKING AND USING - Antibodies having dual specificity for two different but structurally related antigens are provided. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have dual specificity for IL-1α and IL-1β and neutralize IL-1α and IL-1β activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting two different but structurally related antigens (e.g., IL-1α and IL-1β) and for inhibiting the activity of the antigens, e.g., in a human subject suffering from a disorder in which IL-1α and/or IL-1β activity is detrimental. | 06-25-2015 |
Albert Collinson, Marlboro, MA US
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20090232736 | Dual specificity antibodies and methods of making and using - Antibodies having dual specificity for two different but structurally related antigens are provided. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have dual specificity for IL-1α and IL-1β and neutralize IL-1α and IL-1β activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting two different but structurally related antigens (e.g., IL-1α and IL-1β) and for inhibiting the activity of the antigens, e.g., in a human subject suffering from a disorder in which IL-1α and/or IL-1β activity is detrimental. | 09-17-2009 |
Brett Collinson, New York, NY US
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20160110502 | Human and Machine Assisted Data Curation for Producing High Quality Data Sets from Medical Records - A method for building a Patient's Data Set from a Patient's Data File to provide robust patient care comprising the steps of obtaining a Patient's Data File, building a training set for machine learning through experts' selection of at least one desired feature from the Patient's Data File to create the Patient's Data Set, developing a data mining algorithm to automate extraction of at least one data feature from at least one other Patient's Data File using the training set, the algorithm automatically generating the Patient's Data Set from at least one other Patient's Data File, supplementing the Patient's Data Set with at least one patient input, and analyzing the Patient's Data Set to confirm patient course of treatment. | 04-21-2016 |
Daniel K. Collinson, Bellevue, WA US
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20150118146 | SYSTEMS AND METHODS FOR CONTROLLING ON-BOARD GENERATION AND USE OF HYDROGEN FUEL MIXTURES - This is a system for generating hydrogen on-board the vehicle from compressed natural gas (CNG) in select ratios to create hydrogen-enriched CNG (HCNG) fuel for use in internal combustion engines. The on-board generation of hydrogen is comprised of a reforming system of CNG fuel with direct contact with exhaust gases. The reforming system controls for production of HCNG fuel mixtures is based on specific engine operating conditions. The vehicle's engine controls and operating parameters are modified for combustion of selective ratios of HCNG fuel mixtures throughout engine operating cycle. The reforming system controls and engine controls modifications are also used to minimize combustion emissions and optimize engine performance. | 04-30-2015 |
Donald L. Collinson, Lafayette, NY US
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20100309089 | PLANAR ARRAY ANTENNA HAVING RADOME OVER PROTRUDING ANTENNA ELEMENTS - A subarray of a planar array antenna has a ground plane having a rear face and a front face, radiating elements, each of the radiating elements protruding forward of the front face and physically mounted to the ground plane; circuit elements electrically coupled to the radiating elements, and physically mounted to the ground plane and positioned rearward of the rear face of the ground plane; and a dielectric radome supported on the ground plane defining a continuous surface sealed to the ground plane. The continuous surface includes a forward wall positioned forward of each of the radiating elements to form an environmental seal around the radiating elements. The radome has an intermediate wall intermediate at least one pair of adjacent ones of the antenna elements. | 12-09-2010 |
James George Collinson, Winnipeg CA
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20140259939 | Trackless Folding Panel Gate - A foldable panel gate includes an inner panel section and an outer panel section foldable relative to one another between open and closed positions of the gate. An operating linkage controls displacement of the outer panel section relative to the inner panel section as the inner panel section is driven by a suitable drive between the open and closed positions. The linkage includes a pivotal body coupled to the inner panel section, a first connecting link pivotally coupled between the gate post and the pivotal body, and a second connecting link pivotally coupled between the pivotal body and the outer panel section to fold the outer panel section relative to the inner panel section through a range of 180 degrees as the inner panel section is driven through a range of 90 degrees between the open and closed position. | 09-18-2014 |
John P. Collinson, Newcastle Upon Tyne GB
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20120324420 | PROCESS FOR DEVELOPMENT OF MONITORING TOOLS - A process for creation of an equipment health monitoring (EHM) tool, including defining functional requirements for a proposed EHM tool in a structured hierarchical format. The functional requirements definition is used to generate an outline model for a plurality of functions of the proposed EHM tool according to a model template, wherein the outline model is captured as one or more graphical representations. Each graphical representation includes at least one component representative of a defined EHM functional requirement. Source code for the proposed EHM tool is automatically generated based upon the graphically represented model and then compiled to create a deployable EHM tool from the source code by applying a compilation strategy dependent on an intended mode of operation for said EHM tool. An EHM generation tool and associated data carrier are also recited. | 12-20-2012 |
Marc Gibson Collinson, Lonan GB
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20120039586 | ELECTRIC STEAM GENERATION - A steam generator e.g. for a hand-held portable appliance such as a domestic iron or steam cleaner comprises a water inlet, a boiler, a valve for controlling the entry of water into the boiler and means for delivering a surge of water to the boiler when the valve is opened. Also disclosed is an adaptor for supplying electrical power to a mobile electrical appliance. The adaptor is operable in a corded mode when secured to the appliance for supplying electrical power and water while the appliance is being used; or a cordless mode when secured to a base unit such that electrical and water connection can be made by placing the appliance on or against the base unit; and broken by lifting or moving the appliance away from the base unit. | 02-16-2012 |
20120060396 | HAND-HELD STEAM APPLIANCES - A steam generating appliance such as an electric iron comprises a base unit and a hand-held mobile unit which can be releasably coupled to the base unit. The base unit comprises a reservoir for water and a pump for pumping water from the reservoir into the mobile unit when the mobile unit is coupled to the base unit. The mobile unit comprises a boiler and an on-board reservoir for water, wherein the on-board reservoir is adapted to store water received from the base unit under pressure and to deliver the water to the boiler under the control of a user-operable valve. | 03-15-2012 |
Maureen Shannon Collinson, Toronto CA
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20150275302 | DETERMINATION OF SINGLE NUCLEOTIDE POLYMORPHISMS USEFUL TO PREDICT RESPONSE FOR RASAGILINE - This application provides a method for treating a human subject afflicted with Parkinson's disease (PD) with a pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, and a pharmaceutically acceptable carrier, comprising the steps of: | 10-01-2015 |
Michael Collinson, Camarillo, CA US
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20120143006 | ENDOSCOPIC SHEATH ASSEMBLY - A sheath assembly for an endoscope includes an elongate tubular body and a plug. The endoscope has a handle portion and a scope portion extending therefrom to a tip. The body includes first and second wall sections and extends along a longitudinal axis between first and second distal openings located at distal and proximal ends thereof, respectively. The first wall section extends radially about the longitudinal axis to define a scope lumen. The scope portion is receivable in the scope lumen with the distal and proximal ends. The second wall section extends radially about a portion of the first wall section and longitudinally between second distal and proximal end openings. The first and second wall sections define an integral suction lumen in fluid communication with a first source of negative pressure. The plug is mated with the distal end opening and includes a lens surface through which energy is transmissible. | 06-07-2012 |
20120323175 | CATHETER ASSEMBLY - A catheter assembly comprises a first catheter including a wall with an inner surface at least partially defining a lumen. A second catheter is connected to the wall of the first catheter and is disposed outward of the inner surface of the wall. The second catheter is at least partially covered by a sheath portion of the first catheter. A first portion of the wall of the first catheter is made of a relatively low durometer elastomeric material and is relatively extensible. A second portion of the wall is formed of a relatively high durometer elastomeric material and is relatively inextensible. | 12-20-2012 |
20130267777 | ENDOSCOPIC SHEATH ASSEMBLY - A sheath assembly for an endoscope includes an elongate tubular body and a plug. The endoscope has a handle portion and a scope portion extending therefrom to a tip. The body includes first ( | 10-10-2013 |
20140357955 | ENDOSCOPIC SHEATH ASSEMBLY - A sheath assembly for an endoscope includes an elongate tubular body and a plug. The endoscope has a handle portion and a scope portion extending therefrom to a tip. The body includes first and second wall sections and extends along a longitudinal axis between first and second distal openings. The first wall section extends radially about the longitudinal axis to define a scope lumen. The scope portion is receivable in the scope lumen. The second wall section extends radially about a portion of the first wall section and longitudinally between second distal and proximal end openings. The first and second wall sections define an integral suction lumen in fluid communication with a first source of negative pressure. The plug is mated with the distal end opening for closing the scope lumen and includes at least one suction opening disposed in co-registration with the first distal end opening. | 12-04-2014 |
20150314094 | REVERSIBLE AIRWAY DEVICE AND RELATED METHOD FOR VENTILATING A SUBJECT - A reversible airway device can include a tubular guide, a laryngeal mask, and an endotracheal tube. The tubular guide can have a distal end portion, a proximal end portion, and a first passageway extending between the distal and proximal end portions. The tubular guide can further include a first longitudinal seam. The laryngeal mask can be attached to the distal end portion of the tubular guide. The laryngeal mask can include an opening in fluid communication with the first passageway. The laryngeal mask can further include a second longitudinal seam. The endotracheal tube can be slidably disposed within the first passageway and have a second passageway. The first and second longitudinal seams can be adapted to permit ingress and egress of the tubular guide from the airway without detaching the endotracheal tube from a ventilation source. | 11-05-2015 |
Michael Collinson, Gelta, CA US
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20110144425 | Apparatus and Method for Manipulating or Retracting Tissue and Anatomical Structure - Integrated systems and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchoring devices for such purposes. | 06-16-2011 |
20110152607 | Apparatus and Method for Manipulating or Retracting Tissue and Anatomical Structure - Integrated systems and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchoring devices for such purposes. | 06-23-2011 |
Michael Howard D. Hearn Collinson, Caledon CA
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20140199914 | APPARATUS FOR TREATMENT OF PLANTS - A tray for positioning in an exit path of a bee hive comprises a base, a bee entrance end, and a bee exit end. Spaced apart side walls extend upwardly from the base. The sidewalls extend generally lengthwise between the bee entrance end and bee exit end. A plurality of posts extend upwardly from the base and are positioned between the bee entrance end and the bee exit end. The posts are generally circular in cross-section. The posts act as obstacles around which the bees must walk to reach the bee exit end from the bee entrance end. | 07-17-2014 |
20150359204 | APPARATUS FOR TREATMENT OF PLANTS - A bee vectoring apparatus includes a tray for positioning in the exit path of a beehive. The tray includes a bottom, a bee entrance end, and a bee exit end. The apparatus includes a tray lid positioned above the bottom, with first and second barrier walls extruding downwardly from the lid. A ceiling extends between bottom ends of the first and second barrier walls. | 12-17-2015 |
Mike Collinson, Goleta, CA US
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20110251592 | DEVICES FOR MAINTAINING SURGICALLY CREATED OPENINGS - Devices and methods are directed to improving the gaseous exchange in a lung of an individual having, for instance, chronic obstructive pulmonary disease. More particularly, conduits may be deployed in the lung to maintain collateral openings (or channels) surgically created through airway walls. This tends to facilitate both the exchange of oxygen ultimately into the blood and decompress hyper-inflated lungs. The conduit includes a radially expandable center section having a first end, a second end, and a passageway extending from the first end to the second end. A control segment may be associated with the conduit to limit the degree of radial expansion. The conduit further includes a plurality of deflectable members extending from the ends of the center section. A tissue barrier may coaxially surround the conduit such that tissue ingrowth is prevented. The conduits may also include hold-down members and bioactive coatings that serve to prevent ejection of the conduit as well as prevent narrowing of the passageway due to tissue ingrowth. | 10-13-2011 |
Natasha Collinson, Luton GB
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20150382213 | MOBILE COMMUNICATION TERMINAL TEST DEVICE AND MOBILE COMMUNICATION TERMINAL TEST METHOD - A mobile communication terminal test device communicates with a mobile communication terminal to perform a test operation. The test device comprises a display unit, a test engine unit that determines a test procedure to be executed as part of the test operation and communicates the test procedure to a test execution unit which executes the test procedure and returns an outcome of the test procedure execution to the test engine unit, and a display control unit that displays a screen indicating a hierarchical trace of executed test procedures and their outcomes, on the display unit. | 12-31-2015 |
Sarah Jenny Collinson, Hull GB
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20110282309 | WOUND DRESSING AND METHOD OF USE - A system, method, and apparatus are disclosed for dressing a wound. The apparatus comprises a liquid and gas permeable transmission layer, an absorbent layer for absorbing wound exudate, the absorbent layer overlying the transmission layer, a gas impermeable cover layer overlying the absorbent layer and comprising a first orifice, wherein the cover layer is moisture vapor permeable. | 11-17-2011 |
20120136325 | SYSTEMS AND METHODS FOR CONTROLLING OPERATION OF A REDUCED PRESSURE THERAPY SYSTEM - Negative pressure wound therapy apparatuses and dressings, and systems and methods for operating such apparatuses for use with dressings are disclosed. In some embodiments, controlling the delivery of therapy can be based on monitoring and detecting various operating conditions. An apparatus can have a controller configured to monitor the duty cycle of a source of negative pressure and, based on the monitored duty cycle, determine whether a leak is present. The controller can be configured to provide an indication that a leak is present. For example, the controller can be configured to suspend and/or pause the delivery of therapy, and to restart the delivery of therapy due to a timeout, request from a user, etc. In addition, the controller can be configured to pause and/or restart the delivery of therapy upon a request from the user, such as in response to the user operating a switch. | 05-31-2012 |
20120165764 | SYSTEMS AND METHODS FOR CONTROLLING OPERATION OF A REDUCED PRESSURE THERAPY SYSTEM - Negative pressure wound therapy apparatuses and dressings, and systems and methods for operating such apparatuses for use with dressings are disclosed. In some embodiments, controlling the delivery of therapy can be based on monitoring and detecting various operating conditions. An apparatus can have a controller configured to monitor the duty cycle of a source of negative pressure and, based on the monitored duty cycle, determine whether a leak is present. The controller can be configured to provide an indication that a leak is present. For example, the controller can be configured to suspend and/or pause the delivery of therapy, and to restart the delivery of therapy due to a timeout, request from a user, etc. In addition, the controller can be configured to pause and/or restart the delivery of therapy upon a request from the user, such as in response to the user operating a switch. | 06-28-2012 |
20130110058 | REDUCED PRESSURE THERAPY APPARATUSES AND METHODS OF USING SAME | 05-02-2013 |
20140316359 | WOUND DRESSING AND METHOD OF TREATMENT - Embodiments disclosed herein are directed to negative pressure treatment systems and wound dressing systems, apparatuses, and methods that may be used for the treatment of wounds. In particular, some embodiments are directed to improved wound dressings comprising a bridge portion connecting two or more portions of an absorbent layer that facilitates trimming of the wound dressing to suitable sizes. Some embodiments provide for trimming the dressing in a gap between two or more portions of an absorbent layer and sealing the exposed portion of dressing after trimming when the dressing is applied to skin surrounding a wound. | 10-23-2014 |
20150065966 | REDUCED PRESSURE THERAPY APPARATUSES AND METHODS OF USING SAME - Some embodiments comprise a pump assembly for reduced pressure wound therapy, comprising a housing, a flow pathway through the pump, one or more valves in communication with the flow pathway, a pump supported within or by the housing, and a one-way flow valve in fluid communication with the pump. The pump assembly can have a pressure sensor in communication with the flow pathway through the pump, and at least one switch or button supported by the housing, the at least one switch or button being accessible to a user and being in communication with the controller. The one-way flow valve can be configured to substantially prevent a flow of gas through the one-way flow valve in a direction of flow away from the pump. The pump assembly can have a controller supported within or by the housing, the controller being configured to control an operation of the pump. The pump has been sterilized following the assembly of the pump such that an inside and an outside of the housing, the flow pathway, the one or more valves, the pump, the controller, the battery compartment, and the at least one switch or button have been sterilized. | 03-05-2015 |
20150100045 | NEGATIVE PRESSURE WOUND THERAPY APPARATUS - Some embodiments disclosed herein are directed to a pump assembly comprising a voice coil, a magnet and a diaphragm, wherein the voice coil is configured to move the diaphragm to pump a fluid through the pump assembly in response to a drive signal applied to the voice coil. Some embodiments disclosed herein are directed to an apparatus for applying negative pressure to a wound comprising a source of negative pressure configured to be coupled to a dressing, the source of negative comprising a voice coil actuator and a diaphragm, and a controller configured to produce a drive signal for the voice coil actuator. | 04-09-2015 |
20150141941 | APPARATUSES AND METHODS FOR NEGATIVE PRESSURE WOUND THERAPY - Disclosed herein are several embodiments of a negative pressure appliance and methods of using the same in the treatment of wounds. Some embodiments are directed towards wound dressings comprising a liquid and gas permeable transmission layer, an absorbent layer for absorbing wound exudate, the absorbent layer overlying the transmission layer, a gas impermeable cover layer overlying the absorbent layer and comprising a first orifice, wherein the cover layer is moisture vapor permeable. Some embodiments are directed to improved fluidic connectors or suction adapters for connecting to a wound site, for example using softer, kink-free conformable suction adapters. | 05-21-2015 |
20150159066 | COMPOSITION, APPARATUS, KIT AND METHOD AND USES THEREOF - A curable composition for use in wound care comprising, apportioned between at least one Part A and at least one Part B: one or more alkenyl-group containing polymers (i) having at least one alkenyl group or moiety per molecule, one or more SiH-containing polymers (ii) having at least one Si—H unit per molecule; and a catalyst (iii) for curing by addition of alkenyl-containing polymer (i) to SiH-containing polymer (ii), Part A and Part B independently having viscosity at 23° C. in the range 5-300 Pa·s, preferably 10-100 Pa s, at a shearing rate of 10 s | 06-11-2015 |
20150182677 | WOUND DRESSING AND METHOD OF TREATMENT - Embodiments disclosed herein are directed to negative pressure treatment systems and wound dressing systems, apparatuses, and methods that may be used for the treatment of wounds. In particular, some embodiments are directed to improved wound dressings comprising an obscuring layer that may hide fluid contained therein. Some embodiments may further comprise one or more viewing windows disposed therethrough so as to enable monitoring or examination of fluids contained therein. | 07-02-2015 |
20150190286 | WOUND DRESSING AND METHOD OF TREATMENT - Embodiments disclosed herein are directed to negative pressure treatment systems and wound dressing systems, apparatuses, and methods that may be used for the treatment of wounds. In particular, some embodiments are directed to improved wound dressings comprising an obscuring layer that may hide fluid contained therein. Some embodiments may further comprise one or more viewing windows disposed therethrough so as to enable monitoring or examination of fluids contained therein. | 07-09-2015 |
20150216733 | WOUND DRESSING AND METHOD OF TREATMENT - Embodiments disclosed herein are directed to negative pressure treatment systems and wound dressing systems, apparatuses, and methods that may be used for the treatment of wounds. In particular, some embodiments are directed to improved wound dressings comprising an obscuring layer that may hide fluid contained therein. Some embodiments may further comprise one or more viewing windows disposed therethrough so as to enable monitoring or examination of fluids contained therein. | 08-06-2015 |
20150217032 | SYSTEMS AND METHODS FOR CONTROLLING OPERATION OF A REDUCED PRESSURE THERAPY SYSTEM - Negative pressure wound therapy apparatuses and dressings, and systems and methods for operating such apparatuses for use with dressings are disclosed. In some embodiments, controlling the delivery of therapy can be based on monitoring and detecting various operating conditions. An apparatus can have a controller configured to monitor the duty cycle of a source of negative pressure and, based on the monitored duty cycle, determine whether a leak is present. The controller can be configured to provide an indication that a leak is present. For example, the controller can be configured to suspend and/or pause the delivery of therapy, and to restart the delivery of therapy due to a timeout, request from a user, etc. In addition, the controller can be configured to pause and/or restart the delivery of therapy upon a request from the user, such as in response to the user operating a switch. | 08-06-2015 |
20150320604 | WOUND DRESSING AND METHOD OF USE - A system, method, and apparatus are disclosed for dressing a wound. The apparatus comprises a liquid and gas permeable transmission layer, an absorbent layer for absorbing wound exudate, the absorbent layer overlying the transmission layer, a gas impermeable cover layer overlying the absorbent layer and comprising a first orifice, wherein the cover layer is moisture vapor permeable. | 11-12-2015 |
Sarah Jenny Collinson, Heslington GB
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20160120706 | WOUND DRESSING SEALANT AND USE THEREOF - Embodiments disclosed herein are directed to sealing compositions for negative pressure treatment systems and wound dressing systems, devices containing the same, apparatuses, uses and methods for creating a main wound dressing portion for use in wound care, more particularly for sealing a trimmable dressing, having a main dressing portion or cell in fluid (e.g., gas) communication with additional dressing portions or cells, for use in woundcare, more particularly that may be used for the treatment of wounds. In particular, some embodiments are directed to compositions for improving the versatility of wound dressings for wounds of different shapes or sizes. | 05-05-2016 |
Sarah Jenny Collinson, York GB
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20150174304 | REDUCED PRESSURE APPARATUS AND METHODS - Some embodiments have a pump assembly mounted to or supported by a dressing for reduced pressure wound therapy. The dressing can have visual pressure, saturation, and/or temperature sensors to provide a visual indication of the level of pressure, saturation, and/or temperature within the dressing. Additionally, the pump assembly can have a pressure sensor in communication with the flow pathway through the pump, and at least one switch or button supported by the housing, the at least one switch or button being accessible to a user and being in communication with the controller. The pump assembly can have a controller supported within or by the housing, the controller being configured to control an operation of the pump. The pump can be configured to be sterilized following the assembly of the pump such that all of the components of the pump have been sterilized. | 06-25-2015 |
Sarah T. Collinson, Woodland, CA US
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20100287669 | MODULATION OF ACC SYNTHASE IMPROVES PLANT YIELD UNDER LOW NITROGEN CONDITIONS - The invention provides methods for improving plant yield, particularly under nitrogen limiting conditions. According to the invention, applicants have discovered that modulating ACC synthase activity in plants improves yield of plants, even when grown under low nitrogen conditions. The same plants, while demonstrating improved yield over non-modified plants, exhibited no deleterious effects under normal nitrogen conditions. The invention further provides methods using recombinant expression cassettes, host cells and transgenic plants. | 11-11-2010 |
20150284737 | MODULATION OF ACC SYNTHASE IMPROVES PLANT YIELD UNDER LOW NITROGEN CONDITIONS - The invention provides methods for improving plant yield, particularly under nitrogen limiting conditions. According to the invention, applicants have discovered that modulating ACC synthase activity in plants improves yield of plants, even when grown under low nitrogen conditions. The same plants, while demonstrating improved yield over non-modified plants, exhibited no deleterious effects under normal nitrogen conditions. The invention further provides methods using recombinant expression cassettes, host cells and transgenic plants. | 10-08-2015 |