Cuff
Brandon Cuff, Claremont, CA US
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20120066699 | DYNAMIC NATIVE BINDING FOR MANAGED ASSEMBLIES - A method, apparatus, system, article of manufacture, and computer readable storage medium provides the ability to dynamically bind a native assembly from a managed assembly. A managed assembly (e.g., a dynamically linked library (DLL)) is obtained. In the managed assembly, native application program interface entry points are identified. For each of the entry points, intended platform(s) and associated correct native assembly(ies) are specified in the managed assembly. The managed assembly is deployed onto a computer. For example, the single collection of managed and native assemblies can be deployed to all targeted computers, which consist of varying platform environments. During runtime execution, the executing platform of the application is determined. Based on the executing platform, an intended platform is selected and the entry points are bound to the correct native assembly. | 03-15-2012 |
Brian Cuff, Irvington, NY US
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20150113987 | INTEGRATED RENEWABLE ENERGY AND ASSET SYSTEM - An integrated renewable energy and asset system is provided. In some embodiments, the system comprises: an existing parking lot positioned adjacent to a building structure, wherein the existing parking lot has an associated pattern; bore holes that are formed into the existing parking lot, wherein the bore holes are organized based on the pattern of the existing parking lot; vertical columns inserted into at least a first portion of the bore holes, wherein: crossbeams are installed on an upper portion of a vertical column to form a support structure; and a canopy is connected to the crossbeams, wherein the canopy is formed from multiple attached photovoltaic modules and thermal tubes are integrated with the photovoltaic modules; geothermal tubes that capture thermal energy are inserted into at least a second portion of the bore holes, wherein each of the thermal tubes and each of the geothermal tubes is connected to a geothermal heat pump and wherein each of the thermal tubes is connected to the geothermal heat pump; and a hardware processor that is configured to: receive sensor information from sensors disposed on the canopy; determine whether to direct at least a portion of the thermal energy captured using the geothermal tubes to the solar thermal panels based on the received sensor information; and cause the heat captured using the geothermal tubes to be directed to the solar thermal panels based on the determination. | 04-30-2015 |
Carolyn Cuff, Grafton, MA US
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20140161804 | BISPECIFIC IMMUNOBINDERS DIRECTED AGAINST TNF AND IL-17 - Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 06-12-2014 |
20160000936 | BIOMARKERS FOR INFLAMMATORY DISEASE AND METHODS OF USING SAME - The invention provides methods for predicting the efficacy of anti-TNF and anti-IL-17 combination therapies in the treatment of a subject suffering from inflammatory disease by determining the level LIF, CXCL1, CXCL2, CXCL4, CXCL5, CXCL8, CXCL9, CXCL10, CCL2, CCL23, IL-1β, IL-1Ra, TNF, IL-6, IL-10, IL-17A, IL-17F, IL-21, IL-22, IFNγ, CXCR1, CXCR4, CXCR5, GM-CSF, GM-CSFR, G-CSF, G-CSFR protein or nucleic acid, or a homolog, portion or derivative thereof markers in a sample derived from the subject. | 01-07-2016 |
20160002326 | COMPOSITIONS AND METHODS FOR TREATING RHEUMATOID ARTHRITIS - The treatment of rheumatoid arthritis using engineered multivalent and multispecific binding proteins that target TNF and IL-17 is provided. | 01-07-2016 |
Carolyn A. Cuff, Grafton, MA US
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20090311253 | Dual Variable Domain Immunoglobulins and Uses Thereof - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 12-17-2009 |
20110165066 | INTERLEUKIN-13 BINDING PROTEINS - The present invention encompasses IL-13 binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hIL-13 and neutralize hIL-13 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-13 and for inhibiting hIL-13 activity, e.g., in a human subject suffering from a disorder in which hIL-13 activity is detrimental. | 07-07-2011 |
20140099313 | INTERLEUKIN-13 BINDING PROTEINS - The present invention encompasses IL-13 binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hIL-13 and neutralize hIL-13 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-13 and for inhibiting hIL-13 activity, e.g., in a human subject suffering from a disorder in which hIL-13 activity is detrimental. | 04-10-2014 |
20140205613 | ANTI-TNF AND ANTI-IL 17 COMBINATION THERAPY BIOMARKERS FOR INFLAMMATORY DISEASE - The invention provides methods for predicting the efficacy of anti-TNF and anti-IL17 combination therapies in the treatment of a subject suffering from inflammatory disease by determining the level CXCL1 and/or CXCL5 markers in a sample derived from the subject. | 07-24-2014 |
20140335014 | IL-1 ALPHA DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 11-13-2014 |
20150315283 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 11-05-2015 |
Christopher Cuff, Kelso Queensland AU
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20090214408 | PREPARATION AND USE OF CATIONIC HALIDES, SEQUESTRATION OF CARBON DIOXIDE - A process is described for sequestering carbon dioxide. In the process, a carbonate, oxide or hydroxide of a divalent cation is reacted with the carbon dioxide and water and/or with a species resulting from the dissolution of the carbon dioxide in water, to form a hydrogen carbonate of the divalent cation. The carbonate, oxide or hydroxide of the divalent cation has a low solubility in water. The divalent cation of the hydrogen carbonate of the divalent cation thus formed is exchanged for a monovalent cation using an ion exchange medium, to produce a solution of a hydrogen carbonate of the monovalent cation. | 08-27-2009 |
David P. Cuff, Oshkosh, WI US
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20120098172 | GAS SPRING CONTROL SYSTEM AND METHOD - A vehicle suspension system includes a pump, a gas spring, and an accumulator. The suspension system also includes a controller for adjusting the suspension system. The controller has a processing circuit configured to receive a measure of gas in the spring. The processing circuit is further configured to calculate a difference between a target value and a current value based on the received measure of gas. The processing circuit is also configured to provide an output for adjusting the gas in the spring in response to the calculated difference. | 04-26-2012 |
James Cuff, Calgary CA
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20130238290 | CREATING AND LINKING 3D SPATIAL OBJECTS WITH DYNAMIC DATA, AND VISUALIZING SAID OBJECTS IN GEOGRAPHIC INFORMATION SYSTEMS - A method and system of creating and linking 3D spatial objects with dynamic data, and visualizing said objects in geographic information systems (GIS) that includes a front end for a user interface, a database at the back end, and an application layer which processes the data sent between interface and database. A method of generating and uploading Keyhole Markup Language (KML) rings is disclosed. Furthermore, a user specifies a search location, and is shown a view of the available space indicated on the buildings by KML code which is assembled from the database by the system. A method for creating, linking and displaying a three-dimensional spatial object is also disclosed, as well as a method of generating a visual flight between several geographical points, showing the KML structures during the flight. Lastly, a method of showing a cardinal view from a floor of a building in a GIS is disclosed. | 09-12-2013 |
Lisa M. Cuff, Leominster, MA US
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20110184021 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors - A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating polycystic kidney disease in a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. Methods of treating in polycystic kidney disease in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. | 07-28-2011 |
20120322786 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS - A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): | 12-20-2012 |
20120322787 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS - A compound is represented by Structural Formula (I): | 12-20-2012 |
20150225393 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors - A compound is represented by Structural Formula (I): | 08-13-2015 |
Michael Cuff, Clyde Hill, WA US
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20130196773 | Location Services Game Engine - A location services game engine (LSGE) that is concerned with the geographic location of the wireless devices used to play in the game. The operations performed by players on wireless devices inside the location services game engine have location proximity requirements on the wireless devices being played in the game, and other wireless devices they interact with. A common game experience provides a virtual game instance including a plurality of geographically remote playing wireless devices virtually gathered together within the virtual game to physically interact with one another, and traveling relative to one another within the virtual game. A location update of each of the plurality of playing wireless devices active within the virtual game is obtained, with any movement from a last reported position applied against a virtual origin point within the virtual reality game. | 08-01-2013 |
20130267189 | No Responders Online - A rapid assignment dynamic ownership queue for text message sessions queues incoming text messages destined for a service bureau, at a network server. Simultaneous access is provided to any one text message of the queued incoming text messages to a plurality of operator terminals at the service bureau. Initial ownership of the one text message is assigned as a result of a first acting terminal of the plurality of operator terminals having completed an action in service to the text message, and ownership is re-assigned to a subsequent operator terminal having completed another action in service to the text message after the first acting terminal. A configurable escalation queue may be implemented to assign an escalation code to each queued item, regardless of its position in the queue list, to alter the presentation of the queue item. A No Responders Online feature can indicate if all terminal devices are “offline”. | 10-10-2013 |
20130290459 | Configurable Escalation Queue - A rapid assignment dynamic ownership queue for text message sessions queues incoming text messages destined for a service bureau, at a network server. Simultaneous access is provided to any one text message of the queued incoming text messages to a plurality of operator terminals at the service bureau. Initial ownership of the one text message is assigned as a result of a first acting terminal of the plurality of operator terminals having completed an action in service to the text message, and ownership is re-assigned to a subsequent operator terminal having completed another action in service to the text message after the first acting terminal. A configurable escalation queue may be implemented to assign an escalation code to each queued item, regardless of its position in the queue list, to alter the presentation of the queue item. | 10-31-2013 |
20130290460 | Rapid Assignment Dynamic Ownership Queue - A rapid assignment dynamic ownership queue for text message sessions queues incoming text messages destined for a service bureau, at a network server. Simultaneous access is provided to any one text message of the queued incoming text messages to a plurality of operator terminals at the service bureau. Initial ownership of the one text message is assigned as a result of a first acting terminal of the plurality of operator terminals having completed an action in service to the text message, and ownership is re-assigned to a subsequent operator terminal having completed another action in service to the text message after the first acting terminal. A configurable escalation queue may be implemented to assign an escalation code to each queued item, regardless of its position in the queue list, to alter the presentation of the queue item. | 10-31-2013 |
Michael A. Cuff, Clyde Hill, WA US
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20130059608 | Aggregate location dynometer (ALD) - An Aggregate Location Dynometer (ALD) in a physical wireless network alerts to a problematic crowd risk using location based services (LBS). An Aggregate Location Dynometer (ALD) comprises a Network Monitor, a Crowd Risk Determinant and an Alert Module. The Network Monitor monitors wireless traffic for a potential viral event, associated with a formation of a plurality of wireless devices. The Crowd Risk Determinant requests location information associated with a plurality of wireless devices in a given area regarding a respective viral event. The Crowd Risk Determinant determines if the viral event also indicates a crowd safety risk, based on the shape and movement of observed wireless devices. The Alert Module triggers an alert of an impending crowd problem when crowd risk is above a given threshold. Historical databases are empirically determined and maintained in the Aggregate Location Dynometer (ALD) for use in viral event and crowd risk assessment. | 03-07-2013 |
20140155105 | Aggregate Location Dynometer (ALD) - An Aggregate Location Dynometer (ALD) in a physical wireless network alerts to a problematic crowd risk using location based services (LBS). An Aggregate Location Dynometer (ALD) comprises a Network Monitor, a Crowd Risk Determinant and an Alert Module. The Network Monitor monitors wireless traffic for a potential viral event, associated with a formation of a plurality of wireless devices. The Crowd Risk Determinant requests location information associated with a plurality of wireless devices in a given area regarding a respective viral event. The Crowd Risk Determinant determines if the viral event also indicates a crowd safety risk, based on the shape and movement of observed wireless devices. The Alert Module triggers an alert of an impending crowd problem when crowd risk is above a given threshold. Historical databases are empirically determined and maintained in the Aggregate Location Dynometer (ALD) for use in viral event and crowd risk assessment. | 06-05-2014 |
20160044461 | Aggregate Location Dynometer (ALD) - An Aggregate Location Dynometer (ALD) in a physical wireless network alerts to a problematic crowd risk using location based services (LBS). An Aggregate Location Dynometer (ALD) comprises a Network Monitor, a Crowd Risk Determinant and an Alert Module. The Network Monitor monitors wireless traffic for a potential viral event, associated with a formation of a plurality of wireless devices. The Crowd Risk Determinant requests location information associated with a plurality of wireless devices in a given area regarding a respective viral event. The Crowd Risk Determinant determines if the viral event also indicates a crowd safety risk, based on the shape and movement of observed wireless devices. The Alert Module triggers an alert of an impending crowd problem when crowd risk is above a given threshold. Historical databases are empirically determined and maintained in the Aggregate Location Dynometer (ALD) for use in viral event and crowd risk assessment. | 02-11-2016 |
Michael Andrew Cuff, Clyde Hill, WA US
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20140022151 | Wireless Control for Configurable Organic LED (OLED) - A mobile controller application for wirelessly controlling the non-structural appearance of a configurable organic light-emitting diode (OLED) object. A configurable OLED object is fitted with a flexible OLED, a power source, and one or more receptors. A mobile controller application instructs a mobile controller device to send signals, indicating a particular color or display pattern, to one or more receptors embedded in a configurable OLED object. An OLED object receives signals and updates it's non-structural display accordingly. A mobile controller application operates on a mobile controller device. A mobile controller device is preferably a mobile device conventionally used for cell network communication. A mobile controller application enables a user to preview, select, and transmit a display pattern to a configurable OLED object. The inventive mobile controller application also enables a user to store, browse, edit, search, import, export, and categorize display options, which are maintained in a local image database. | 01-23-2014 |
Nicola Jane Cuff, Auckland NZ
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20140194374 | Anthelmintic Formulations and Treatments - A new method of controlling worm burden in ruminants by using two different injectable anthelmintics at or about the same time to increase the time between treatments and to rely on the animal's immune response. One of the anthelmintics is a long acting formulation capable of providing a sustained release of abamectin or other macrocyclic lactone for 2-14 days, to enable the anthelmintic to remove or kill incoming larvae for a sufficiently long period of time to allow the host to recognise the incoming larvae as foreign, and thus allow the ruminant to mount an immune response against these incoming larvae. The other is a short acting anthelmintic such as levamisole designed to substantially eliminate the initial parasite population of adults, juveniles and larvae. They can be combined into a single injectable formulation with a high percentage of levamisole (preferably over 30% of the formulation w/v) together with about 1% w/v of a macrocyclic lactone such as abamectin, dissolved in glycerol formal. | 07-10-2014 |
Philip Anthony Frederick Cuff, New South Wales AU
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20160099950 | USER AUTHENTICATION - A method, system, server processing system and computer readable medium for authenticating a user attempting to access a secure environment is disclosed. In one aspect, the server processing system is configured to: receive an authentication request to authenticate the user attempting to access the secure environment; transfer, to the user or a user device associated with the user, an index corresponding to a selected key from a keymap; receive data indicative of a code which is based on the selected key presented by the user device and a personal identifier, and determine, using the code whether the user is authenticated. Advantageously, the server processing system never stores nor receives data directly indicative of the personal identifier such that no one else is able to determine the personal identifier, not even an employee of the secure environment which the user is attempting to access. | 04-07-2016 |
Simon Cuff, London GB
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20130091519 | PROCESSING AND APPARATUS FOR ADVERTISING COMPONENT PLACEMENT - A method of presenting advertising opportunities to users of a digital advertising placement system is described. The method includes receiving sequences of video material from a video material source, the sequences of video material having been processed from original video material to select parts of the original video material which are suitable for placement of digital advertising components. The method further includes incorporating the received sequences of video material into an online catalog accessible to a plurality of users via a data communications network, the online catalog allowing remote access to a user to identify one or more sequences which are of interest to an advertiser wishing to conduct digital advertising placement using said system. | 04-11-2013 |
20140147096 | SYSTEM AND METHOD OF PRODUCING CERTAIN VIDEO DATA - A system and method of incorporating additional video objects into source video data to produce output video data. A method includes identifying segments of the source video data, selecting identified segments for the inclusion of additional video objects, creating an intermediate working version of the source video data including video material corresponding to the selected segments, creating metadata which identifies at least one frame within the source video data which corresponds to the selected segments, transmitting the intermediate working version to a remote system for the creation of additional video data including additional video objects to be included in the output video data, receiving video file data associated with the additional video data, obtaining the additional video data based on the video file data, retrieving metadata and incorporating the additional video data with the source video data on the basis of the retrieved metadata to produce the output video data. | 05-29-2014 |
20140150013 | SYSTEM AND METHOD OF PRODUCING VIDEO DATA - A system and method for incorporating one or more additional video objects into input video data to produce output video data. A method includes retrieving the input video data, analysing the input video data to identify one or more desired visual attributes for the one or more additional video objects to possess when incorporated into the input video data, creating instructions for generating additional video data comprising the one or more additional video objects having the one or more desired visual attributes and transmitting at least the instructions to a first remote system that has already received at least part of the input video data, the instructions being useable by the remote system to generate the additional video data for incorporation into the input video data. | 05-29-2014 |
Stan Cuff, Auburn, NY US
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20140263698 | APPARATUS AND SYSTEM FOR DELIVERING WATER AND NUTRIENTS TO CROPS, AND METHOD THEREOF - The present invention relates to an apparatus for delivering water and nutrients to crops. The present invention also relates to a system comprising the apparatus of the present invention connected to a hose traveler device. Also disclosed is a method of delivering water and nutrients to the soil using the system of the present invention. | 09-18-2014 |