Cuppen
Edwin Cuppen, Utrecht NL
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20140041063 | Genetically Modified Rat Models for Obesity and Diabetes - This invention relates to a genetically modified or chimeric rat cell whose genome comprises chromosomal alleles of an obesity-diabetes gene (especially, the Mc4r gene or Lep gene), wherein at least one of the two alleles contains a mutation, or the progeny of this cell. The obesity or diabetes gene may affect any of the pathways of obesity and diabetes. The obesity or diabetes gene may predispose the rat to a phenotype of obese and diabetic, lean and diabetic, obese and non-diabetic, non-obese and diabetic or any of the combinations thereof. In another aspect, the invention relates to a desired rat or a rat cell which contains a predefined, specific and desired alteration rendering the rat or rat cell predisposed to obesity or diabetes. | 02-06-2014 |
Edwin Pieter Cuppen, Utrecht NL
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20130178387 | NUCLEIC ACID MOLECULES AND COLLECTIONS THEREOF, THEIR APPLICATION AND MODIFICATION - The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof. | 07-11-2013 |
Edwin Pieter Johan Cuppen, Utrecht NL
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20130190379 | SMALL RNA MOLECULES, PRECURSORS THEREOF, MEANS AND METHODS FOR DETECTING THEM, AND USES THEREOF IN TYPING SAMPLES - The invention is related to small RNA molecules, precursors thereof and methods for detecting such molecules. The invention is in particular concerned with differentially expressed small RNA molecules and precursors thereof. Various collections of small RNA molecules, precursors thereof and collections of probe and primers that can be used to detect small RNA molecules, precursors thereof are provided. Further provided are diagnostic test based on this differential expression. Also provided are therapeutic applications using one or more of the members of the presented collections. | 07-25-2013 |
Edwin Pieter Johan Gerard Cuppen, Bilthoven NL
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20140005251 | MiRNA for Treating Diseases and Conditions Associated with Neo-angiogenesis | 01-02-2014 |
Edwin P.j.g. Cuppen, Bilthoven NL
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20100035760 | Nucleic Acid molecules and Collections Thereof, Their Application and Modification - The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof. | 02-11-2010 |
20110136891 | Nucleic acid molecules and collections thereof, their application and Identification - Provided is a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) as disclosed herein or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides new nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof. | 06-09-2011 |
Edwin P.j.g. Cuppen, Utrecht NL
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20090215865 | Nucleic Acid Molecules and Collections Thereof, Their Application and Identification - The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides new nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof. | 08-27-2009 |
Johannes Josephus Maria Cuppen, Veldhoven NL
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20100160713 | DEVICE AND METHOD FOR ELECTROMAGNETIC STIMULATION OF A PROCESS WITHIN LIVING ORGANISMS - Device for applying an electromagnetic field for stimulation of a process within a living organism when applied to at least part of a body, comprising a driver for generating a time varying drive signal and a transducer responsive to said drive signal for generating a time varying electromagnetic field signal B(t). The signal B(t) comprises a superposition of two or more periodic base signals b | 06-24-2010 |
20100197992 | COIL STRUCTURE FOR ELECTROMAGNETIC STIMULATION OF A PROCESS WITHIN A LIVING ORGANISM, DEVICE USING SUCH COIL STRUCTURE AND METHOD OF DRIVING - A distributed electromagnetic coil structure for applying a time varying electromagnetic field to a population of living organisms is described. The coil structure comprises at least a substantially planar first coil sub-structure. The first coil sub-structure comprises at least a first wire of a predetermined shape and a least a second wire of a predetermined shape, wherein said first and second wire are shaped to define one or more of first cells. An electromagnetic field is generated by said first cells when a current runs through said first coil sub-structure. | 08-05-2010 |
Martinus Antonius Maria Cuppen, Mierlo NL
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20120085078 | GUIDANCE CHAIN FOR GUIDING CABLES OR OTHER LINES IN A MEDICAL DIAGNOSTIC APPARATUS - The invention relates to a guidance chain ( | 04-12-2012 |
Martinus Antonius Maria Cuppen, Eindhoven NL
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20090298414 | PRECISION APPARATUS HAVING A MOVABLE MEMBER, AN AIR SLIT AND A VACUUM DUCT - A precision apparatus has a movable member (A), moving in a bridge element ( | 12-03-2009 |
20120155616 | BIDIRECTIONAL MOVEMENT ASSEMBLY - The present invention relates to motor assisted movement as well as to mobile X-ray systems comprising at least one bidirectional wheel. Positioning heavy objects in in particular confined spaces with high precision may be a cumbersome and tedious task. Consequently, a motor assisted movement assembly as well as an X-ray system comprising at least one bidirectional wheel is presented. According to the present invention a motor assisted movement assembly ( | 06-21-2012 |
Roel Peter Geert Cuppen, Venio NL
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20130300314 | Setting up hybrid coded-light - ZigBee lighting system - A lighting system ( | 11-14-2013 |
Roel Peter Geert Cuppen, Venlo NL
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20120194095 | MULTI-DIMENSIONAL CONTROL OF LIGHTING PARAMETERS - A multi-dimensional controller ( | 08-02-2012 |
20130182411 | Tangible navigation of color temperature and light intensity | 07-18-2013 |
20140285096 | Coded light transmission and reception - There is provides an illumination system which comprises a plurality of luminaries or light sources. Each luminary or light source comprises a light driver capable of receiving and storing a dynamic light effect pattern, and from the dynamic light effect pattern creating a light effect. The color and/or intensity of the luminary or light source is thereby dynamically varied. The light driver is further arranged to embed data in the light effect. Each luminary or light source further comprises a light emitter for emitting the light effect comprising the encoded data. A light detector is arranged to receive light emitted by other luminaries or light sources in the illumination system. A light decoder is arranged to decode data out of light received by the detector and arranged to determine the intensity of the light received. | 09-25-2014 |
20150022123 | Remote control of light source - A lighting system comprises a set of light sources and a remote control unit. The remote control unit comprises a user interface through which a user may identify an area in an image and a light source. The identified image area is linked with the light source and color information of the identified image area is transmitted to the light source. The light source is thereby enabled to adapt its light output to the color information. A user is thereby enabled to pick the color to be outputted by a light source by selecting an area in an image displayed on the remote control unit. The remote control unit may be part of a mobile telephone, a tablet computer, an electronic photo frame, or a television screen. | 01-22-2015 |
20150070133 | IDENTIFICATION SENSOR FOR GATE IDENTIFICATION OF A PERSON - The invention relates to an identification sensor ( | 03-12-2015 |
Roel Peter Geert Cuppen, Eindhoven NL
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20110276152 | APPARATUS AND METHOD FOR PROVIDING SETTINGS OF A CONTROL SYSTEM FOR IMPLEMENTING A SPATIAL DISTRIBUTION OF PERCEPTIBLE OUTPUT - An apparatus for providing settings of a control system ( | 11-10-2011 |
20120176783 | LIGHTING DEVICE - A lighting device | 07-12-2012 |
20140257573 | ADAPTIVE CONTROL OF AMBIENCE SETTINGS - The invention relates to a method and to an apparatus that enables the ambience of e.g. hospital rooms to adapt according the scheduled or non-scheduled activities throughout the day. The ambience generated by lights, sound devices, image, movie displays and other devices is controlled by an ambience controller ( | 09-11-2014 |
Roel P.g. Cuppen, Eindhoven NL
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20100225810 | METHOD FOR SYNCHRONIZING A CONTENT STREAM AND A SCRIPT FOR OUTPUTTING ONE OR MORE SENSORY EFFECTS IN A MULTIMEDIA SYSTEM - A method for synchronizing a content stream ( | 09-09-2010 |
20100318201 | METHOD AND SYSTEM FOR DETECTING EFFECT OF LIGHTING DEVICE - A method comprises transmitting an operate signal from a control system to an effects device, operating the effects device according to the operate signal, detecting an effect of the effects device, assigning a location to said effect, and storing the location of said effect. The effects device can comprise a lighting device, and the method can be repeated for multiple effects devices. | 12-16-2010 |