Dalby
Amy Dalby, Woodridge, IL US
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20150057204 | Maleanized Ester Derivatives - This disclosed invention relates to a maleinated ester derivative derived from an unsaturated linear aliphatic carboxylic acid methyl ester, maleic anhydride, and a monohydric alcohol. Lubricants and functional fluids containing the maleinated esters are disclosed. | 02-26-2015 |
Amy Dalby, Woodstock, IL US
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20140274832 | MALEINIZED ESTER DERIVATIVES - This disclosed invention relates to a maleinated ester derivative derived from an unsaturated linear aliphatic carboxylic acid methyl ester, maleic anhydride, and a monohydric alcohol. Lubricants and functional fluids containing the maleinated esters are disclosed. | 09-18-2014 |
Bert S. Dalby, Wayne, PA US
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20100153296 | Method of administering an investment fund providing a targeted payout schedule - An investment fund that offers shares to investors, which shares provide to their holders a predictable stream of payments over some period. Each payment in the stream of payments is scheduled to be made according to a targeted payment schedule that is established by the investment fund at the time of its creation. The investment fund receives purchase requests and funds from interested investors and invests the funds in securities that provide payments that are used to meet or approximate the targeted payment schedule. A preferred form of the investment fund invests the received funds in Treasuries whose interest or coupon payments and/or principal payments or maturities approximately map to the targeted payment schedule. Principal (or maturity) and interest (or coupon) payments made by the Treasuries are used to provide payments to the investors when such payments become due according to the targeted payment schedule. | 06-17-2010 |
Brian Dalby, Carlsbad, CA US
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20120100522 | STABILIZED CHEMICAL DEHYDRATION OF BIOLOGICAL MATERIAL - The present invention provides compositions and methods that enable the stabilization and storage of samples by contacting a sample with an assembly of particles, and reducing the water activity level of the contacted sample. By reducing the water activity level of the sample, the assembly of particles minimizes the degradation of the sample. Stabilizers may or may not be added to the assembly of particles to further minimize the degradation of the sample. Subsequently to storage in the assembly of particles, the samples are recoverable by eluting the assembly of particles with a fluid solution. In one embodiment, the entire assembly of particles will dissolve into the solution. In another embodiment, only part of the assembly of particles will dissolve into the solution. The assembly of particles provides the advantage that while it is porous, it comprises non-porous particulate material. | 04-26-2012 |
Christina Dalby, Boulder, CO US
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20120148664 | CHEMICAL MODIFICATIONS MOTIFS FOR MIRNA INHIBITORS AND MIMETICS - The present invention provides polynucleotides having chemistry patterns that provide for improved stability, potency, and/or toxicity relative to their use as miRNA inhibitors or miRNA mimetics. The invention further provides pharmaceutical compositions and formulations comprising the polynucleotides, and methods for treating patients having a condition associated with miRNA or mRNA expression. | 06-14-2012 |
20120184596 | MICRORNA INHIBITORS COMPRISING LOCKED NUCLEOTIDES - The invention provides chemically modified oligonucleotides capable of inhibiting the expression (e.g., abundance) of miR-208 family miRNAs, including miR-208a, miR-208b, and/or miR-499. The invention provides in some embodiments, oligonucleotides capable of inhibiting, in a specific fashion, the expression or abundance of each of miR-208a, miR-208b, and miR-499. The invention further provides pharmaceutical compositions comprising the oligonucleotides, and methods of treating patients having conditions or disorders relating to or involving a miR-208 family miRNA, such as a cardiovascular condition. In various embodiments, the oligonucleotides provide advantages in one or more of potency, efficiency of delivery, target specificity, toxicity, and/or stability. | 07-19-2012 |
20130296402 | BASE MODIFIED OLIGONUCLEOTIDES - The present invention relates to oligonucleotides with base modified nucleosides for enhancement of binding affinity. | 11-07-2013 |
20130345288 | INHIBITORS OF THE MIR-15 FAMILY OF MICRO-RNAS - The invention provides chemically modified oligonucleotides capable of inhibiting the expression (e.g., abundance) of miR-15 family miRNAs, including miR-15 | 12-26-2013 |
20140066491 | CHEMICAL MODIFICATION MOTIFS FOR MIRNA INHIBITORS AND MIMETICS - The present invention provides polynucleotides having chemistry patterns that provide for improved stability, potency, and/or toxicity relative to their use as miRNA inhibitors or miRNA mimetics. The invention further provides pharmaceutical compositions and formulations comprising the polynucleotides, and methods for treating patients having a condition associated with miRNA or mRNA expression. | 03-06-2014 |
20140187603 | MICRORNA INHIBITORS COMPRISING LOCKED NUCLEOTIDES - The invention provides chemically modified oligonucleotides capable of inhibiting the expression (e.g., abundance) of miR-208 family miRNAs, including miR-208a, miR-208b, and/or miR-499. The invention provides in some embodiments, oligonucleotides capable of inhibiting, in a specific fashion, the expression or abundance of each of miR-208a, miR-208b, and miR-499. The invention further provides pharmaceutical compositions comprising the oligonucleotides, and methods of treating patients having conditions or disorders relating to or involving a miR-208 family miRNA, such as a cardiovascular condition. In various embodiments, the oligonucleotides provide advantages in one or more of potency, efficiency of delivery, target specificity, toxicity, and/or stability. | 07-03-2014 |
Christina M. Dalby, Boulder, CO US
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20130344135 | OLIGONUCLEOTIDE-BASED INHIBITORS COMPRISING LOCKED NUCLEIC ACID MOTIF - The present invention relates to chemical modification motifs for oligonucleotides. The oligonucleotides of the present invention, such as chemically modified antisense oligonucleotides, can have increased in vivo efficacy. The chemically modified oligonucleotides provide advantages in one or more of potency, efficiency of delivery, target specificity, toxicity, and/or stability. The chemically modified oligonucleotides have a specific chemical modification motif or pattern of locked nucleic acids (LNAs). The oligonucleotide (e.g. antisense oligonucleotide) can target RNA, such as miRNA or niflNA. Also provided herein are compositions comprising the chemically modified oligonucleotides and methods of using the chemically modified oligonucleotides as therapeutics for various disorders, including cardiovascular disorders. | 12-26-2013 |
Glenn Dalby, Seattle, WA US
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20140323378 | Coating Systems - The invention relates to a coating system, in particular a coating system containing an organometallic layer which allows the selective removal of post coating layers from substrates without detrimental impact to their “in-service” performance. The organometallic layer comprises (a) an organic polymer containing multi-chelating functionalities; and (b) a metallic agent which forms an organo metallic complex with the organic polymer containing multi-chelating functionalities and is located between an optionally coated substrate and at least one post coating layer of a coating system. | 10-30-2014 |
Glenn R. Dalby, Shoreline, WA US
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20090257070 | APPARATUS AND METHOD FOR APPLICATION AND ACCURATE POSITIONING OF GRAPHICS ON A SURFACE - In an embodiment of the invention, there is provided an apparatus for application and accurate positioning of at least one graphic image on a large contoured surface, comprising a flexible-rail positioning system mounted on a portion of the surface on which the graphic image is to be applied, a graphic image application system, software to operate the positioning system, and software to operate the graphic image application system. In another embodiment of the invention, there is provided a method of applying and accurately positioning at least one graphic image on a large contoured surface. | 10-15-2009 |
20110199431 | Apparatus for Application and Accurate Positioning of Graphics on a Surface - In an embodiment of the invention, there is provided an apparatus for application and accurate positioning of at least one graphic image on a large contoured surface, comprising a flexible-rail positioning system mounted on a portion of the surface on which the graphic image is to be applied, a graphic image application system, software to operate the positioning system, and software to operate the graphic image application system. In another embodiment of the invention, there is provided a method of applying and accurately positioning at least one graphic image on a large contoured surface. | 08-18-2011 |
20150044420 | Coatings, Coating Compositions, and Methods of Delaying Ice Formation - A coating includes at least one coating layer containing first particles, second particles, and third particles distributed throughout a cross-linked, continuous polymer matrix. An outer surface of the coating layer includes surfaces of at least first particles extending outward from a top periphery of the polymer matrix. The outer surface exhibits a property of delaying ice formation compared to the coating layer without the first particles. A method includes applying a coating composition in one application step. The one-step coating composition contains first particles, second particles, and third particles in a base containing a polymer. A coating composition includes first particles, second particles, and third particles distributed in a matrix precursor. | 02-12-2015 |
Jean-Louis Dalby, Gratens FR
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20100218114 | Method for Simplifying the Display of Stationary Members of an Onboard Database - The invention is situated in the field of displaying on board an aircraft geostationary elements of the navigation database on a screen having different display resolutions for the purpose of this data display, and its subject is a method for simplifying the display of stationary elements of this onboard database. This method is characterized in that it consists in precalculating a “decluttering” during the process of producing the onboard database by meshing the Earth with a Cartesian grid oriented along the latitudes and longitudes of the Earth, and by allowing only the most pertinent obstacle to appear in each rectangle of this grid. | 08-26-2010 |
Kevin N. Dalby, Cedar Park, TX US
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20130129812 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER - Provided herein are methods and compositions inter alia for treating diseases, including hyperproliferative diseases, migraine headaches, and depression. | 05-23-2013 |
20150306077 | Novel Compositions and Methods for Treating Cancer - Provided herein are methods and compositions inter alia for treating diseases, including hyperproliferative diseases, migraine headaches, and depression. | 10-29-2015 |
Paul Joseph Dalby, Colorado Springs, CO US
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20140081252 | TISSUE SLITTING METHODS AND SYSTEMS - Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures. | 03-20-2014 |
20140081303 | TISSUE SLITTING METHODS AND SYSTEMS - Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures. | 03-20-2014 |
20140081304 | TISSUE SLITTING METHODS AND SYSTEMS - Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures. | 03-20-2014 |
20140081306 | TISSUE SLITTING METHODS AND SYSTEMS - Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures. | 03-20-2014 |
Richard N. Dalby, Lutherville, MD US
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20110318277 | TACROLIMUS COMPOSITIONS FOR AEROSOL ADMINISTRATION - The present disclosure relates generally to highly concentrated macrolide solutions for aerosol administration, and related methods of producing and administering the same. In one aspect, provided herein is a receptacle containing a highly concentrated solution of a macrolide compound such as tacrolimus, where the solution exhibits long-term stability in a pMDI canister and achieves high respirable fractions when actuated, among, other features. In yet another aspect, provided is a composition suitable for aerosol administration comprising tacrolimus dissolved in an ethanol-liquified propellant mixture, characterized by a tacrolimus concentration of greater than 0.15 weight percent (w/w) and comprising no more than about 10 weight percent (w/w) ethanol. | 12-29-2011 |
Rolf Dalby, Engelsvik NO
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20150354743 | ARRANGEMENT AND METHOD FOR LINING PIPES - The invention relates to lining of pipes, whereby a liner ( | 12-10-2015 |
Rolf Ivar Dalby, Engelsviken NO
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20130156506 | Method for Renewal or Rehabilitation of Water Supply Pipelines and Plug Arrangement for use in Said Method - Method for renewal or rehabilitation of water supply pipelines without the need for excavation of the pipes or associated side inlets, manholes, etc., wherein plug arrangements are installed in side inlets, a flexible hose applied with adhesive is threaded into the water supply pipeline, and certain pressure is maintained for a predetermined period of time in order to get the adhesive material hardened and the hose glued to the inner pipe wall, and wherein the mounted plug arrangements are removed. A special plug arrangement for use in said method is also provided. | 06-20-2013 |
Timothy James Dalby, Edmonton CA
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20120284202 | SYSTEMS AND METHODS FOR DETERMINING SUITABILITY OF REAL ESTATE - Systems and methods relating to the determination of notable locations around a specific address. The notable locations within a predetermined radius of the specific address are mapped and noted. Each notable location within that radius contributes (either increases or decreases) a score for a particular category. Each category relates to a particular concern that might relate to a specific demographic or segment of the population. The score for each category is then presented to a user. The user may also enter a ranking of the various categories and specific addresses whose scores are in line with the user's ranking may also be presented to the user. The notable locations around a specific address may be found in a database supplied by the municipality or any other source or may be derived from a digital map of the area. | 11-08-2012 |