Dobbin
Caroline A. Dobbin, Queensland AU
Patent application number | Description | Published |
---|---|---|
20090047240 | CHAPERONIN 10-INDUCED IMMUNOMODULATION - The present invention relates to methods for modulating Toll-like receptor signalling in a subject, or in at least one cell, tissue or organ thereof, methods for treating or preventing a disease or condition in a subject, methods for modulating the production and/or secretion of one or more immunomodulators in a subject, or at least one cell, tissue or organ thereof, wherein said methods involve the administration of chaperonin 10, and wherein the chaperonin 10 associates with a Toll-like receptor in an activation cluster. Also contemplated are associated compositions and uses thereof. | 02-19-2009 |
Caroline Amanda Dobbin, Holland Park AU
Patent application number | Description | Published |
---|---|---|
20120014998 | MODIFIED CHAPERONIN 10 - The present invention relates to isolated Chaperonin 10 polypeptides possessing immunomodulatory activity, but lacking, or substantially lacking, protein folding activity. | 01-19-2012 |
20140093524 | MODIFIED CHAPERONIN 10 - The present invention relates to isolated Chaperonin 10 polypeptides possessing immunomodulatory activity, but lacking, or substantially lacking, protein folding activity. | 04-03-2014 |
Caroline Amanda Dobbin, Holland Park Qld AU
Patent application number | Description | Published |
---|---|---|
20090325882 | CHAPERONIN 10 MODULATION OF TOLL-LIKE RECEPTOR-INDUCIBLE CYTOKINE AND CHEMOKINE SECRETION - Methods of use of Chaperonin 10 (Cpn10) are provided for regulating Toll-like receptor signaling and/or Toll-like receptor inducible immunomodulator secretion. Cpn10 negatively regulates Toll-like receptor agonist-induced pro-inflammatory cytokine and chemokine secretion, examples being IL-6 and RANTES, respectively. Cpn10 positively regulates Toll-like receptor agonist-induced anti-inflammatory cytokine and chemokine secretion, an example being IL-10. These immunoregulatory activities of Cpn10 may be useful in the treatment of diseases, disorders and conditions resulting from excessive pro-inflammatory cytokine and chemokine secretion. This invention also relates to producing, designing and/or screening Cpn10 agonists and antagonists according to their ability to regulate Toll-like receptor signaling and/or Toll-like receptor inducible immunomodulator secretion. | 12-31-2009 |
Caroline Amanda Dobbin, Queensland AU
Patent application number | Description | Published |
---|---|---|
20090305400 | Modified chaperonin 10 - A novel granule dispersion composition which comprises water and, dispersed therein, a finely pulverized, sparingly water-soluble substance. The granule dispersion composition is prepared by dispersing in water a granular material which comprises a specific substance sparingly soluble in water, a polymer, and an oil and has an average particle diameter of 1 μm or smaller and in which the ratio of the total weight of the polymer and oil to the weight of the specific substance is 1.5 or higher. | 12-10-2009 |
Christopher John Brooke Dobbin, Calgary CA
Patent application number | Description | Published |
---|---|---|
20080281033 | Long fiber reinforced composites - A composite comprising from about 20 to 40 weight % of fiber reinforcing having a nominal length of not less than 1.25 cm, from about 1 to 10 weight % of a polar polymer and from 79 to 50 weight % of a polyolefin prepared using a single site catalyst has improved physical properties over comparable compositions made using polyolefins made using Ziegler Natta catalysts. The composites are suitable in many applications including construction and particularly in making concrete forms. | 11-13-2008 |
20080289274 | Half panel - The present invention provides a half panel having on its back ribs defining symmetrically complimentary closed wall open faced cells and ribs having spaces there between. The half panel may be placed in back to back relationship and rotated through a required degree of rotation so that the open faced closed wall cells and ribs having spaces there between interlock so the open faced closed wall cells have at least one diagonal cross member. This provides a rigid panel suitable for a number of applications including forms for pouring concrete. | 11-27-2008 |
Elizabeth Dobbin, San Francisco, CA US
Patent application number | Description | Published |
---|---|---|
20110238536 | METHODS AND SYSTEMS FOR REDUCING ITEM SELECTION ERROR IN AN E-COMMERCE ENVIRONMENT - Methods and systems for displaying, to a user interface, categories of items for the user to select from for querying the system, in order to enable the system to return to the user images of items of the type desired by the user for possible purchase. The items categories of items can be presented to the user interface visually in silhouette form so that the user can select brand and the silhouette image of the type of item desired. Upon selection of the silhouette image, a query is sent to the system and images of the desired type of item are returned to the user interface for presentation to the user, along with certain attributes of the items. | 09-29-2011 |
Geoffrey E. Dobbin, West Valley City, UT US
Patent application number | Description | Published |
---|---|---|
20110232176 | Modular Plant Support Structure - The present invention is a modular support for vine plants and tomato plants. It comprises a solid, cylindrical base with holes to accept posts and associate tier rings. A cover may also be provided to transform the base into a miniature hot house. Notches may be formed in the rim of the base to accommodate irrigation systems and stake ends may be provided for the posts to allow immediate securement of the posts to the ground rather than the base. The solid base contains water, mulch and other beneficial compounds for the plants and helps block the spread of weeds immediately around the plant. As the plant grows, additional tiers may be added to the support to increase its size. The parts are preferably made of a durable plastic so as to support larger plants and increase longevity of the support. | 09-29-2011 |
James Dobbin, Bath GB
Patent application number | Description | Published |
---|---|---|
20090126619 | Assembly for Deploying a Payload from a Submarine - A submarine ( | 05-21-2009 |
Kalon Dobbin, Palmerston North NZ
Patent application number | Description | Published |
---|---|---|
20100043254 | SPORTS SHOE - A sports shoe that has a shell provided with at least one reinforcing member in the form of a flexible hollow body. | 02-25-2010 |
Richard Dobbin, Bristol GB
Patent application number | Description | Published |
---|---|---|
20150300397 | CAP WITH CHANNELS FOR FORMING A SEALED CAVITY AROUND FASTENER - A cap for forming a sealed cavity around one end of a fastener, the cap having a two-piece construction comprising an outer cap member and an inner cap member. A quantity of sealant is provided between the inner and outer cap members which, upon installation of the cap, is urged to flow between the inner and outer cap members and collect at the base of the outer cap member, to form a bead of sealant around the circumference of the cap, sufficient to adhere the cap to the structure when the sealant cures. A plurality of channels are provided between the inner and outer cap members to facilitate the flow of sealant. | 10-22-2015 |
Richard Dobbin, Chepstow GB
Patent application number | Description | Published |
---|---|---|
20130322982 | CAP FOR FORMING SEALED CAVITY AROUND FASTENER - A joint comprising: a structure; and a fastener passing through the structure. The cap has a body portion with an annular base terminating at an edge, the body portion forming an enclosure around an end of the fastener. The cap also has an annular flange which extends outwardly from the body portion and is set back from the edge of the base so as to define a pocket between the flange and the base. A sealant is provided in the pocket between the flange and the base, the sealant bonding the cap to the structure via a sealant/cap interface with the cap and a sealant/structure interface with the structure. The surface area of the sealant/cap interface is greater than the surface area of the sealant/structure interface. | 12-05-2013 |
20140048198 | FLANGED CAP FOR FORMING SEALED CAVITY AROUND FASTENER - A cap has a body portion forming a central cavity, and an annular flange which extends outwardly from the body portion. The body portion is deformable between a first configuration in which the annular flange is inclined upwardly, and a second configuration in which the annular flange is inclined downwardly. A method includes applying a quantity of sealant to the annular flange in the first configuration; fitting the cap over the end of the fastener so that the fastener is enclosed by the cap; and turning down the annular flange such that the cap assumes the second configuration in which an annular pocket is formed between the flange and the base, and the sealant material fills the annular pocket; and bonding the cap to the structure with the sealant material. | 02-20-2014 |
20140341675 | INJECTABLE NUT CAP - The description provides a method of forming a seal around an end of a fastener protruding from a structure. The cap includes a cap body with a cavity; a sealing material inlet comprising an opening in the cap body; three or more ridges protruding from the cap body into the cavity; and three or more channels between the ridges. The method includes: installing the cap body over the end of the fastener so that it is enclosed within the cavity and contacted by the ridges; injecting sealing material into the cavity via the sealing material inlet so that the sealing material flows along the channels, fills the cavity, contacts the end of the fastener, and contacts the structure; and curing the sealing material to form the seal. | 11-20-2014 |
20150104270 | FASTENER FOR AIRCRAFT STRUCTURES - A fastener is provided for an aircraft structure, the fastener comprising a shaft and a bugle shaped head, in which the bugle head comprises a first region proximate the shaft, the first region having a first radius of curvature, and, a second region on the opposite side of the first region to the shaft, the second region having a second radius of curvature, in which the second radius of curvature is higher than the first radius of curvature. | 04-16-2015 |
20150184688 | INJECTABLE NUT CAP - The present invention proposes a cap for forming a sealed cavity around one end of a fastener to thereby contain out-gassing and sparking events in the event of a lightning strike to the fastener. The invention also proposes a joint comprising such a cap, and a kit of parts and method for installing such a cap. A cap according to the invention comprises: an inner cap member having an annular base terminating at an edge which surrounds an opening into an air cavity for enclosing the one end of a fastener; and an outer cap member having an annular skirt or flange which extends radially outwardly away from the annular base, the annular skirt or flange and annular base between them defining an annular sealing cavity. The cap also comprises a sealing material inlet comprising an opening in the outer cap member that is in fluid communication with the annular sealing cavity, the opening being arranged to interconnect with a sealing material injection device to provide a flow of curable sealing material from the sealing material inlet into the annular sealing cavity. | 07-02-2015 |
Sarah Dobbin, Ottawa CA
Patent application number | Description | Published |
---|---|---|
20100008079 | LED INSPECTION LAMP AND LED SPOTLIGHT - An LED inspection lamp has plurality of LED sources for emitting electromagnetic radiation at different peak wavelengths for causing visible fluorescence in different leak detection dyes. A lens is associated with each LED. Radiation passing through lenses is superimposed in target area at target distance. Another LED inspection lamp has plurality of LEDs emitting electromagnetic radiation at a peak wavelength. A lens adaptor has lens housing for attachment to LED inspection lamp with a single LED for causing visible fluorescence, and a lens. Substantially all of the radiation from the LED passes through the lens and is focused in a target area at a target distance from the lenses. LED spot lights have a similar configuration. The LEDs may produce white light from distinct LEDs or from white LEDs. The light may be a flashlight or fixed spot light. | 01-14-2010 |
20100008082 | LED work light - A light comprising an LED whose light intensity decreases as the angle from an axis of the LED increases, and a convex lens associated with the LED such that a beam width of the LED is concentrated by the lens into a narrower beam width, wherein the convex lens includes both a convex surface and a concave surface, and the concave surface is curved more sharply towards its edge than towards its center such that light is more evenly spread across the beam width of the lens. | 01-14-2010 |
Sarah Katherine Dobbin, Ottawa CA
Patent application number | Description | Published |
---|---|---|
20100228122 | MICROBUBBLE MEDICAL DEVICES - Method and medical devices for generating and stabilizing micro- or nano-bubbles, and systems and methods for therapeutic applications using the bubbles, are provided. The micro-bubbles may be used to enhance therapeutic benefits such as ultrasound-guided precision drug delivery and real-time verification, acoustic activation of large tumour masses, enhanced acoustic activation through longer retention of therapeutic agents at the point of interest, enhancement of high intensity focused ultrasound treatments, light activation of photodynamic drugs at a depth within a patient using extracorporeal light sources, probes, or sonoluminescence, and initiation of time reversal acoustics focused ultrasound to permit highly localized treatment. | 09-09-2010 |
20140148687 | MICROBUBBLE MEDICAL DEVICES - Method and medical devices for generating and stabilizing micro or nano bubbles, and systems and methods for therapeutic applications using the bubbles, is provided. Two novel bubble generating means are provided: in-line capillary tubes and mix chambers flow focusing, and cross flow bubble generation with optimized bubble detachment means. A method and medical device to stabilize bubble sizes and improve bubble size homogeneity through rectified diffusion is disclosed. A method and system to facilitate acoustic activation of therapeutic agents using ultrasound energy is provided. | 05-29-2014 |
Vincent William Dobbin, Gosport GB
Patent application number | Description | Published |
---|---|---|
20110287712 | System for wireless communications through sea vessel hull - The present invention discloses a system for wireless communications and/or data transfer through a sea-vessel hull by means of electric and/or magnetic coupling between first and second transducers located on opposing sides of the hull. Transmit and receive transducers located on opposing sides of the hull are clamped around cables which penetrate the hull and which are fed through pressure hull glands in the hull. The inductive transducers couple electric and/or magnetic signals through the sea vessel hull via paths through the pressure hull glands or via paths through the cables. The system for wireless communication and/or data transfer of the present invention is capable of operation through an electrically conductive sea vessel hull which would ordinarily present a physical barrier against the transmission of such signals. The system can be deployed on an ad ad-hoc basis and is capable of providing high data rate and high bandwidth communications and/or data transfer through the sea vessel hull. The system does not interfere with existing cabled systems penetrating the hull via the pressure hull glands. In particular, the system of the present invention requires no modification of existing hardware nor does it require any modification of the hull for operation. | 11-24-2011 |