Patent application number | Description | Published |
20080242722 | Combination Therapy for Treating Cyclooxygenase-2 Mediated Diseases or Conditions in Patients at Risk of Thrombotic Cardiovascular Events - The invention is directed to a method for treating a cyclooxygenase-2 mediated disease or condition in a mammalian patient at risk of a thrombotic cardiovascular event, wherein the patient is on aspirin therapy to reduce the risk of the thrombotic cardiovascular event, | 10-02-2008 |
20100022477 | FUSED AROMATIC PTP-1B INHIBITORS - The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown (Formula I) above and methods of treating or preventing PTP-1B mediated diseases, including diabetes. | 01-28-2010 |
20100137371 | Novel Pharmaceutical Compounds - The instant invention provides compounds of Formula (I) which are leukotriene biosynthesis inhibitors. Compounds of formula (I) are useful as anti-asthmatic, anti-allergic, anti-inflammatory, cytoprotective and anti-artherosclerotic agents. | 06-03-2010 |
20110275660 | BETA CARBOLINE SULPHONYLUREA DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS - The invention is directed to β-carboline sulphonylurea derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, inflammation, osteoarthritis, and rheumatoid arthritis. Pharmaceutical compositions and methods of use are also included. | 11-10-2011 |
20120178679 | FUSED AROMATIC PTP-IB INHIBITORS - The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown (Formula I) above and methods of treating or preventing PTP-1B mediated diseases, including diabetes. | 07-12-2012 |
20130281365 | FUSED AROMATIC PTP-1B INHIBITORS - The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown (Formula I) above and methods of treating or preventing PTP-1B mediated diseases, including diabetes. | 10-24-2013 |
20150045325 | FUSED AROMATIC PTP-1B INHIBITORS - The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown (Formula I) above and methods of treating or preventing PTP-1B mediated diseases, including diabetes. | 02-12-2015 |
Patent application number | Description | Published |
20100065423 | Capping Board Section and Assembly with Reinforced Mating Projection - The invention concerns a capping board assembly and its multiple connectable sections. Each pair of sections is connected with an interlocking joint, each of which comprises at least one projection and at least one recess that cooperate and prevent the longitudinal and lateral movement of the sections. Each interlocking joint is reinforced by a rod embedded within the section and extending within the projection. The rod has a tip that anchors the projection. The interlocking joints allow precision assembly of the sections of the capping board which greatly benefits strength, installation, replacement and transportation. | 03-18-2010 |
20140183057 | Contact Bar with Multiple Support Surfaces and Insulating Capping Board - The present invention related to a contact bar or contact bar segment, a contact bar and insulating capping board assembly and a method for operating an electrolytic cell including electrodes for refining metal. Embodiments of the contact bar include support sections with multiple support surfaces for lying against the insulating capping board, thereby distributing weight of the electrodes hanging on the contact bar; and contact sections for receiving the electrodes while providing good electrical contact and precise positioning thereof. While following the steps of the method for operating the electrolytic cell, lifetime of the contact bar and insulating capping board may be increased. | 07-03-2014 |
20140291471 | HOOK WITH HOLDING MEANS AND METHOD FOR HOLDING DOWN UNDERGROUND TANK WITH A STRAP - A hook, a hold down strap and a method for holding down an underground tank. The hook includes a base portion connectable to the hold down strap; a curved portion extending from the base portion and defining a concave receiving area having an entrance sized and configured for receiving an anchor element. The hook includes at least one hooking aid member being a flexible member or an extension member. The flexible member extends across the entrance of the concave receiving area and is sized and configured to bend from a closed position to an open position such that, when the anchor element traverses the entrance, the flexible member bends from the closed position toward the concave receiving area to the open position, thus allowing the anchor element to enter the concave receiving area. The extension member extends from the curved portion beyond the entrance of the concave receiving area. | 10-02-2014 |
Patent application number | Description | Published |
20100044451 | Insulating Anti-Corrosive Rail Clamp Integrally Made of Polymeric Composition - The invention relates to a rail clamp for fastening rail equipment, said rail clamp being integrally composed of a polymeric composition produced by pultrusion or molding, vacuum molding or compression molding. It has high mechanical strength. It is anticorrosive and insulating and is preferably composed of a resin and reinforcing fibers and/or a thermoplastic. It is advantageously formed as a one piece structure. The rail clamp is especially used to fasten rails to base slabs and has economic advantages compared to the rail clamps known in the art, which are made of steel coated with rubber. | 02-25-2010 |
20110132753 | Contact Bar for Capping Board - Disclosed is a contact bar for use on a capping board of a given length in order to electrically connect a plurality of anodes and cathodes extending in spaced apart, alternate positions in adjacent electrolytic cells all along the capping board. The contact bar extends over the length of the capping board and is of a given average cross-section. This contact bar comprises a central core that is made of an insulating material and extends all over its length. This contact bar also comprises a plurality of contact pieces that are made of an electrically conductive material and are positioned in spaced apart positions all along the core, each of the pieces defining a segment on which only a short number of the anodes and cathodes are connected. Due to such a division of the contact bar into segments formed by the contact pieces that are no more an electrical contact with each other thanks to the core made of insulating material, any short circuit that occurs by accident is no more “transferred” to all the electrodes of the cells. It is actually transmitted only to the few electrodes in contact with the segment(s) to which is connected the electrode that may cause the trouble. | 06-09-2011 |
20130032474 | Contact Bar for Capping Board - Disclosed is a segmented contact bar for use boarding an electrolytic cell. The segmented contact bar has contact pieces made of electrically conductive material and being in spaced apart relation along the capping board, each of the contact pieces defining a segment for supporting and electrically connecting an anode and a cathode in the electrolytic cell. The segmented contact bar also has connection members including an insulating material and provided in between pairs of adjacent segments for providing insulating interconnection of the segments. There is also an electrolytic refining apparatus including adjacent electrolytic cells; a capping board positioned on the adjacent electrolytic cells; anodes and cathodes extending in spaced apart alternate positions into the each of the adjacent electrolytic cells along the capping boards; and a segmented contact bar. | 02-07-2013 |
20150048172 | INSULATING ANTI-CORROSIVE RAIL CLAMP INTEGRALLY MADE OF POLYMERIC COMPOSITION - The invention relates to a rail clamp for fastening rail equipment, said rail clamp being integrally composed of a polymeric composition produced by pultrusion or molding, vacuum molding or compression molding. It has high mechanical strength. It is anticorrosive and insulating and is preferably composed of a resin and reinforcing fibers and/or a thermoplastic. It is advantageously formed as a one piece structure. The rail clamp is especially used to fasten rails to base slabs and has economic advantages compared to the rail clamps known in the art, which are made of steel coated with rubber. | 02-19-2015 |
Patent application number | Description | Published |
20110076192 | STERILIZATION METHOD AND APPARATUS - A method of sterilizing an article by sequentially exposing the article to hydrogen peroxide and ozone is disclosed. The article is exposed under vacuum first to an evaporated aqueous solution of hydrogen peroxide and subsequently to an ozone containing gas. The exposure is carried out without reducing the water vapor content of the sterilization atmosphere, the water vapor content being derived from the aqueous solvent of the hydrogen peroxide solution and from the decomposition of the hydrogen peroxide into water and oxygen. The complete sterilization process is carried out while the chamber remains sealed and without removal of any component of the sterilization atmosphere. For this purpose, the chamber is initially evacuated to a first vacuum pressure sufficient to cause evaporation of the aqueous hydrogen peroxide at the temperature of the chamber atmosphere. The chamber is then sealed for the remainder of the sterilization process and during all sterilant injection cycles. Keeping the chamber sealed and maintaining the hydrogen peroxide and its decomposition products in the chamber for the subsequent ozone sterilization step results in a synergistic increase in the sterilization efficiency and allows for the use of much lower sterilant amounts and sterilization cycle times than would be expected from using hydrogen peroxide and ozone in combination. | 03-31-2011 |
20130236355 | STERILIZATION METHOD AND APPARATUS - Disclosed is a method of sterilizing an article by sequentially exposing the article under vacuum first to a gaseous conditioning agent for forming radicals and then to a sterilant. The preferred conditioning agent is hydrogen peroxide and the preferred sterilant is ozone. The chamber is initially evacuated to a first vacuum pressure and then sealed for the remainder of the sterilization process and during all sterilant injection cycles, without removal of any component of the sterilization atmosphere, which means without any measures to reduce the water vapor content. Keeping the chamber sealed and maintaining the conditioning agent and the radicals generated thereby in the chamber for the sterilization with sterilant results in a synergistic increase in the sterilization efficiency and allows for the use of much lower sterilant amounts and sterilization cycle times than would be expected from using the conditioning agent and the sterilant in combination. | 09-12-2013 |
20130243649 | HYDROGEN PEROXIDE STERILIZATION METHOD - A method of controlling unwanted condensation of hydrogen peroxide in a sterilization chamber at a preselected temperature is disclosed. The method includes the steps of maintaining the sterilization chamber at a vacuum pressure below the pressure at which hydrogen peroxide will boil at the preselected temperature, evaporating successive pulses of hydrogen peroxide, and injecting the evaporated hydrogen peroxide into the chamber, whereby the volume of each pulse of hydrogen peroxide is less than 75 μL, preferably less than 35 μL, most preferably less than 20 μL. Sterilization results are improved by controlling unwanted condensation of hydrogen peroxide. | 09-19-2013 |