Fitzgerald, GB
Daniel Fitzgerald, Wetherby GB
Patent application number | Description | Published |
---|---|---|
20130209386 | NEW USES - An antibacterial or anti-acne formulation containing (a) tropone or a substituted tropone and (b) a metal or metal salt selected from copper, copper salts, bismuth, bismuth salts, silver, silver salts, and mixtures thereof, for use in the treatment of either acne or body odour. The substituted tropone may be for example tropolone or hinokitiol. | 08-15-2013 |
Daniel James Fitzgerald, Lees GB
Patent application number | Description | Published |
---|---|---|
20100310478 | SUBSTITUTED BENZOQUINONES AND HYDROQUINONES IN THE TREATMENT OF PERIODONTAL DISEASES - An alkyl- or halo-substituted benzoquinone, hydroquinone or mixture thereof, for use in the treatment of a periodontal disease, and/or for use in the treatment of a condition which is caused by, transmitted by or exacerbated by | 12-09-2010 |
Daniel James Fitzgerald, Yorkshire GB
Patent application number | Description | Published |
---|---|---|
20130316016 | ANTIBACTERIAL OR ANTI-ACNE FORMULATIONS CONTAINING USNIC ACID OR AN USNATE AND A METAL SALT - An antibacterial or anti-acne formulation suitable for topical or local application to human skin containing (a) either usnic acid or an usnate and (b) a metal salt selected from copper salts, bismuth salts, and mixtures thereof, wherein if the component (a) is an usnate, the components (a) and (b) are not the same compound. | 11-28-2013 |
Daniel James Fitzgerald, Leeds GB
Patent application number | Description | Published |
---|---|---|
20080262097 | Formulations - An antimicrobial formulation containing (a) a peroxide selected from the group consisting of diacyl peroxides, alkyl hydroperoxides and metal peroxides and (b) a benzoquinone or hydroquinone. The formulation may in particular be used against staphylococci or propionibacteria, more particularly to treat skin and skin structure conditions such as acne. | 10-23-2008 |
20090030086 | ANTIMICROBIAL AGENTS - A benzoquinone or hydroquinone for use in the topical treatment of a condition which is caused, exacerbated or transmitted by bacterial, in particular staphylococcal or propionibacterial, activity. The condition may be a skin or skin structure condition such as acne. The invention also provides the use of a benzo- or hydroquinone in the manufacture of a medicament for the treatment of such a condition. | 01-29-2009 |
20090246292 | ANTIMICROBIAL FORMULATIONS COMPRISING A QUINONE AND A COPPER SALT - An antimicrobial formulation containing a quinone, such as a benzoquinone or hydroquinone, and a copper salt. The formulation may in particular be used against staphylococci or propionibacteria, more particularly to treat skin and skin structure conditions such as acne. | 10-01-2009 |
20090306218 | Antimicrobial formulations - An antimicrobial formulation containing a synergistic combination of a quinone, such as an optionally substituted benzoquinone or hydroquinone, and a bismuth salt. The formulation may in particular be used against propionibacteria, more particularly to treat skin and skin structure conditions such as acne, or against microbial infections within the oral cavity. | 12-10-2009 |
20100273876 | ANTIBACTERIAL FORMULATION COMPRISING A DIALKYL SULPHOSUCCINATE AND A CARBANILIDE ANTIBACTERIAL AGENT - Antibacterial formulation containing (a) a dialkyl sulphosuccinate (DAS) or derivative thereof and (b) a carbanilide antibacterial agent such as triclocarban (TCC). The formulation may be for use in the treatment of a bacterial condition, in particular acne, body odour or a condition affecting the oral cavity. It may contain, in addition to the DAS and the carbanilide, (i) a poly-oxyalkylene-based solubilising agent; (ii) an organic solvent; (iii) a thickening agent; and (iv) water. | 10-28-2010 |
Daniel T. Fitzgerald, Winchester GB
Patent application number | Description | Published |
---|---|---|
20150089356 | Text Selection - Mechanisms for selecting text within a displayed document comprises mechanisms for performing the operations of displaying a document comprising continuous text, receiving user input defining a single continuous area of the displayed document, the defined area covering text within the displayed document that is non-continuous, and capturing the text within the defined area. Objects can also be selected with the tool, and multiple areas can also be selected in the same way, all of which can be of any shape that the user desires. | 03-26-2015 |
Darren Paul Fitzgerald, Merseyside GB
Patent application number | Description | Published |
---|---|---|
20110256325 | COATED GLAZING - Coated Glazing comprising a pane of glass having an innermost surface and an outermost surface, and a coating layer (e.g. a titania coating and an underlying fluorine-doped tin oxide coating) on the outermost surface of the pane. The glazing has an emissivity of 0.7 or less and its outermost coated surface is both hydrophilic and photoactive (after any necessary initial activation period) with a water droplet contact angle of 30° or less, the glazing thereby having the capability of reducing or preventing the tendency for condensation to form on its outermost surface and the facility for maintaining the water droplet contact angle at or below 30°. Also disclosed is a method of reducing or preventing the tendency for condensation to form on the outermost surface of a glazing. | 10-20-2011 |
David Fitzgerald, London GB
Patent application number | Description | Published |
---|---|---|
20150049497 | Z-SHAPED LAMP PANEL - Disclosed is a Z-shaped lamp panel applied in a lamp and configured as a comb-shaped body. The Z-shaped lamp panel includes an installing portion disposed at a position corresponding to a comb-handle position and a plurality of carrying portions corresponding to comb-tooth positions respectively. The installing portion is coupled to a side of the carrying portions, and the carrying portions are arranged with an interval apart from each other and provided for installing a plurality of light emitting diodes. Therefore, the cost of the lamp panel can be reduced while the lamp can maintain the light emitting diodes in a matrix form to ensure a maximum illumination range. | 02-19-2015 |
Emma Fitzgerald, Clayton-Le-Woods GB
Patent application number | Description | Published |
---|---|---|
20130105839 | SEMICONDUCTOR NANOPARTICLE-BASED MATERIALS FOR USE IN LIGHT EMITTING DIODES, OPTOELECTRONIC DISPLAYS AND THE LIKE | 05-02-2013 |
Emma Fitzgerald, Leyland GB
Patent application number | Description | Published |
---|---|---|
20110241229 | ENCAPSULATED NANOPARTICLES - In various embodiments, the present invention relates to production of encapsulated nanoparticles by dispersing said nanoparticles and an encapsulating medium in a common solvent to form a first solution system and applying a stimulus to said first solution system to induce simultaneous aggregation of the nanoparticles and the encapsulating medium. | 10-06-2011 |
John Fitzgerald, Bushey, Watford, Hertfordshire GB
Patent application number | Description | Published |
---|---|---|
20150247786 | ON-DEMAND VAPOUR GENERATOR - An on-demand vapour generator includes a vapour chamber configured to produce a vapour and a vapour absorption assembly configured to receive flows of vapour from the vapour chamber. The vapour absorption assembly includes a first vapour-permeable passage having a passage outlet and at least one second vapour-permeable passage that is closed. When vapour absorption assembly receives a flow of vapour from the vapour chamber, the flow of vapour passes through the first vapour-permeable passage to the passage outlet at least substantially without absorption of vapour from the flow of vapour. However, when a flow of vapour is not received from the vapour chamber, vapour entering the vapour absorption assembly from the vapour chamber passes into the first vapour-permeable passage and the at least one second vapour-permeable passage and is at least substantially absorbed. | 09-03-2015 |
John Patrick Fitzgerald, Watford GB
Patent application number | Description | Published |
---|---|---|
20090133469 | Vapour Generators - A vapour generator system ( | 05-28-2009 |
20120175516 | VAPOUR GENERATORS - A vapour generator system ( | 07-12-2012 |
20150129756 | INTEGRATED CAPACITOR TRANSIMPEDANCE AMPLIFIER - Spectrometers including integrated capacitive detectors are described. An integrated capacitive detector integrates ion current from the collector ( | 05-14-2015 |
20150136965 | CAPACITIVE TRANSIMPEDANCE AMPLIFIER WITH OFFSET - Spectrometers including integrated capacitive detectors are described. An integrated capacitive detector integrates ion current from the collector ( | 05-21-2015 |
20150192209 | INLET CLOSURE MECHANISM - An inlet closure assembly includes a housing that defines an inlet configured to receive a fluid, such as airflow from the surrounding environment. The inlet closure assembly also includes a seal member that defines an inlet path in fluid communication with the inlet defined by the housing. The inlet closure assembly further includes a seat member configured to seat with respect to the seal member. The seat member is configured to obstruct the inlet path in its seated orientation. The inlet closure assembly also includes an actuation member configured to move the seat member into and out of seated engagement with the seal member. The inlet closure assembly further includes a biasing member for biasing the seat member into seated engagement with the seal member when the seat member is positioned to obstruct the inlet. The biasing member can be implemented using a magnet, a spring, and so forth. | 07-09-2015 |
Liam Fitzgerald, Wakefield GB
Patent application number | Description | Published |
---|---|---|
20110225879 | SEPARATION SYSTEM AND METHOD - A separation system and method for separating one or more solid fossil fuels from a contaminated source in a liquid medium, the system including primary separation means and secondary separation means, the primary and secondary separation means being arranged to operate with liquid media of differing specific gravities. | 09-22-2011 |
Mary Fitzgerald, Harlow GB
Patent application number | Description | Published |
---|---|---|
20080318912 | Medicaments for Treating Chronic Respiratory Disease - There is provided the use of a methylxanthine compound and a steroid in a synergistic combination for the treatment of a respiratory disease, wherein the methylxanthine compound is administered at a dose, which, in isolation, is not effective to treat said disease. | 12-25-2008 |
Mary Fitzgerald, Essex GB
Patent application number | Description | Published |
---|---|---|
20090191217 | Anti-IL-1R1 Single Domain Antibodies And Therapeutic Uses - Disclosed is the use of an antagonist of Interleukin 1 receptor type 1 (IL-1R1) for the manufacture of a medicament treating, preventing or suppressing lung inflammation or a respiratory disease. In some embodiments of the described invention, the medicament is for local administration to pulmonary tissue. Also disclosed are methods for treating lung inflammation or a respiratory disease. | 07-30-2009 |
Mary F. Fitzgerald, Harlow GB
Patent application number | Description | Published |
---|---|---|
20120114651 | METHODS FOR TARGETING PULMONARY DISEASES WITH AGENTS THAT BIND A TARGET IN PULMONARY TISSUE - Disclosed is the use of an agent (e.g., antibody fragment, antagonist, ligand, dAb monomer) that binds a target in pulmonary tissue for the manufacture of a long action or long therapeutic window formulation for local delivery to pulmonary tissue, and methods for administering an agent that binds a target in pulmonary tissue to a subject to produce a long therapeutic window in pulmonary tissue. The formulation is for, and the method comprises, administering locally to pulmonary tissue. Also disclosed is the use of antagonists of TNFR1 for the manufacture of a formulation or medicament for treating, preventing or suppressing lung inflammation or a respiratory disease, and methods of treating such diseases. Also disclosed are the use of agents a for the manufacture of a delivery device (e.g., inhaler, intranasal delivery device) for the treatment or prevention of lung inflammation or a respiratory disease, and a delivery device for the treatment or prevention of lung inflammation or a respiratory disease that contains an agent as described herein. | 05-10-2012 |
20130309227 | METHODS FOR TARGETING PULMONARY DISEASES WITH AGENTS THAT BIND A TARGET IN PULMONARY TISSUE - Disclosed is the use of an agent (e.g., antibody fragment, antagonist, ligand, dAb monomer) that binds a target in pulmonary tissue for the manufacture of a long action or long therapeutic window formulation for local delivery to pulmonary tissue, and methods for administering an agent that binds a target in pulmonary tissue to a subject to produce a long therapeutic window in pulmonary tissue. The formulation is for, and the method comprises, administering locally to pulmonary tissue. Also disclosed is the use of antagonists of TNFR1 for the manufacture of a formulation or medicament for treating, preventing or suppressing lung inflammation or a respiratory disease, and methods of treating such diseases. Also disclosed are the use of agents a for the manufacture of a delivery device (e.g., inhaler, intranasal delivery device) for the treatment or prevention of lung inflammation or a respiratory disease, and a delivery device for the treatment or prevention of lung inflammation or a respiratory disease that contains an agent as described herein. | 11-21-2013 |
Mary F. Fitzgerald, Oxford GB
Patent application number | Description | Published |
---|---|---|
20100022537 | I-PHENY 1-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE DERIVATIVES AND THEIR USE - This invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development. | 01-28-2010 |
Mary F. Fitzgerald, Essex GB
Patent application number | Description | Published |
---|---|---|
20090111795 | Multimers of Heterocyclic Compounds and Their Use - A compound of formula (I): M-L-M, wherein L is a linker and each M is independently a group of formula (II): is useful in therapy, e.g. of respiratory diseases. | 04-30-2009 |
20100034831 | Agents that Bind a Target in Pulmonary Tissue for Targeting Respiratory Diseases - Disclosed is the use of an agent (e.g., antibody fragment, antagonist, ligand, dAb monomer) that binds a target in pulmonary tissue for the manufacture of a long action or long therapeutic window formulation for local delivery to pulmonary tissue, and methods for administering an agent that binds a target in pulmonary tissue to a subject to produce a long therapeutic window in pulmonary tissue. The formulation is for, and the method comprises, administering locally to pulmonary tissue. Also disclosed is the use of antagonists of TNFR1 for the manufacture of a formulation or medicament for treating, preventing or suppressing lung inflammation or a respiratory disease, and methods of treating such diseases. Also disclosed are the use of agents a for the manufacture of a delivery device (e.g., inhaler, intranasal delivery device) for the treatment or prevention of lung inflammation or a respiratory disease, and a delivery device for the treatment or prevention of lung inflammation or a respiratory disease that contains an agent as described herein. | 02-11-2010 |
Mary Frances Fitzgerald, Harlow GB
Patent application number | Description | Published |
---|---|---|
20100324002 | Inhaled combination therapy - There is provided the use of a methylxanthine derivative such as theophylline and a steroid in a synergistic combination for the treatment of chronic obstructive pulmonary disease, wherein the combination is administered by the inhaled route for pulmonary delivery. | 12-23-2010 |
Mary Frances Fitzgerald, Essex GB
Patent application number | Description | Published |
---|---|---|
20080318913 | Combination of Methylxanthine Compounds and Steroids to Treat Chronic Respiratory Diseases - There is provided the use of a methylxanthine derivative such as theophylline and a steroid in a synergistic combination for the treatment of chronic obstructive pulmonary disease, wherein the combination is administered by the inhaled route for pulmonary delivery. | 12-25-2008 |
20090105268 | Dihydropyrimidone Multimers and Their Use as Human Neutrophil, Elastase Inhibitors - A compound of formula M-L-M (I) wherein L is a linker and each M is independently a group of formula (II) is useful in therapy, e.g. of respiratory diseases. | 04-23-2009 |
Mary Frances Fitzgerald, Buckinghamshire GB
Patent application number | Description | Published |
---|---|---|
20130203716 | Inhaled Combination Therapy - There is provided the use of a methylxanthine derivative such as theophylline and a steroid in a synergistic combination for the treatment of chronic obstructive pulmonary disease, wherein the combination is administered by the inhaled route for pulmonary delivery. | 08-08-2013 |
Peter Fitzgerald, Crumlin GB
Patent application number | Description | Published |
---|---|---|
20120003674 | Chloral Hydrate Detection - The invention relates to an immunoassay method and kit for the indirect detection of chloral hydrate. The invention is underpinned by a novel immunogen that produces an antibody that is specific for the chloral hydrate metabolite trichloroethanol glucuronide. Detection and quantification of trichloroethanol glucuronide has important applications in clinical toxicology, drug facilitated crime, water testing and solvent exposure. | 01-05-2012 |
20130210167 | IMMUNOASSAY FOR PYRROLIDINOPHENONES - The invention describes antibodies that bind molecules of the pyrrolidinophenone class of synthetic drugs. The antibodies are derived from novel chemical intermediates, haptens and immunogens and are used in methods and kits to detect and quantify pyrrolidinophenones. | 08-15-2013 |
20130224878 | BIOCHIP WELL, SEALED WELL ASSEMBLY, CARTRIDGE THEREFOR, AND APPARATUS AND METHODS FOR OPENING SEALED WELLS - A biochip well is disclosed, including a vessel containing a well therewithin, the vessel forming at least base and side walls of the well and defining at least one aperture giving access to the well, and further including retaining means for holding a biochip at a predetermined position within the well, the well including a laterally offset region into which the biochip does not protrude when held at the predetermined position by the retaining means. Also disclosed are sealed well assemblies and apparatus and methods for opening sealed wells. | 08-29-2013 |
20130224882 | Assay for the Detection of the Phenylpiperazine Family - The current invention describes novel immunogens which are used in the production of novel antibodies with unique binding properties in that they cross-react with a variety of phenylpiperazine derivatives. These antibodies enable methods and kits to detect and/or determine phenylpiperazine derivatives (for example mCPP, TFMPP and MeOPP) in an in vitro sample which are advantageous over currently available analytical methods in terms of cost, ease of use, speed and sensitivity. | 08-29-2013 |
20140099651 | IMMUNOASSAYS FOR MEPERIDINE AND METABOLITES - The invention provides novel haptens and immunogens for the preparation of novel monoclonal antibodies, which detect the synthetic opioid meperidine and its active metabolite normeperidine. These antibodies enable methods and kits, which are useful in an immunoassay for therapeutic drug monitoring (TDM) and in extending the window of detection for cases of abuse and drug-facilitated sexual assault (DFSA). | 04-10-2014 |
20140147859 | Venlafaxine Assay - The invention describes antibodies that bind venlafaxine and O-desmethylvenlafaxine. The antibodies are derived from novel haptens and immunogens and are used in methods and kits to detect and quantify venlafaxine and O-desmethylvenlafaxine. The invention also describes novel detecting agents which can be used in the methods and kits of the invention. | 05-29-2014 |
20140242617 | Immunoassay for Detecting Kratom, its Constituents and their Use - The invention relates to the field of drug detection and describes antibody-based components methods and kits for the detection and quantification of alkaloids of the plant kratom. The invention is underpinned by novel antibodies which specifically bind to mitragynine alkaloids found in the kratom plant and their metabolites. | 08-28-2014 |
20140242618 | Ritalinic Acid Immunoassay - The invention provides novel antibodies which specifically bind to the methylphenidate metabolite, ritalinic acid, enabling an immunoassay that can detect methyphenidate in biological samples for an extended period following its ingestion. The invention also describes novel conjugates and kits incorporating the antibodies. | 08-28-2014 |
20140287441 | IMMUNOASSAY FOR CYCLOPROPYLINDOLE BASED SYNTHETIC CANNABINOIDS, METABOLITES AND DERIVATIVES THEREOF - The invention relates to the detection and quantification of cyclopropylindole based synthetic cannabinoids UR-144 and XLR-11 by providing antibodies based on novel immunogens. These antibodies can be incorporated into methods and kits for the detection of UR-144, XLR-11 and their metabolites. | 09-25-2014 |
20140336283 | GENETIC FACTORS IN BLOOD PRESSURE - The invention describes epistatic interactions between single nucleotide polymorphisms on genes associated with blood pressure and provides an application for their use in a method to determine an individual's susceptibility to hypertension and hence whether anti-hypertensive treatment will be beneficial for said individual. In addition gene expression levels are also linked to blood pressure and may also be used to determine susceptibility to hypertension. | 11-13-2014 |
20150038366 | Immunoassay for Phenethylamines of the 2C and DO Sub-Families - Immunoassay methods and their requisite components for the detection and determination of phenethylamines of the 2C and DO sub-families are described. | 02-05-2015 |
20150269311 | DIAGNOSIS AND RISK STRATIFICATION OF BLADDER CANCER - The invention provides a method of defining the likelihood of a subject having bladder cancer, comprising the steps of: | 09-24-2015 |
20150346226 | IMMUNOASSAY FOR COMPOUNDS OF THE NBOMe FAMILY - An immunoassay method for detecting and determining ‘NBOMe’ family designer drugs is described. Also described are components for use in implementing the method, namely, antibodies, detection agents, solid state devices and kits as well as immunogens used to raise the antibodies. | 12-03-2015 |
20150346227 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE ADAMANTYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY - An immunoassay method for detecting and determining adamantane substituted indazole and indole synthetic cannabinoids is described. Also described are components for use in implementing the method, namely, antibodies, detection agents, solid state devices and kits as well as immunogens used to raise the antibodies. | 12-03-2015 |
20160084859 | DETECTION OF INDAZOLE SYNTHETIC CANNABINOIDS - Components for enabling immunodection of indazole synthetic cannabinoids are described including immunogens, haptens, antibodies, methods and kits. | 03-24-2016 |
20160097783 | IMMUNOASSAY FOR PYRROLIDINOPHENONES - The current invention provides an improved immunoassay for the detection and determination of pyrrolidinophenone based designer drugs in hair and biological fluids (urine, blood, and oral fluid). The generic immunoassay is underpinned by novel, sub-family-specific antibodies, which display surprising sensitivity. The invention further describes substrates comprising an antibody that is specific to compounds of the pyrrolidinophenone family. Also described are the novel immunogens from which the antibodies are derived and kits incorporating the antibodies of the current invention. | 04-07-2016 |
20160097784 | DETECTION OF POLYMYXINS - The present invention relates to antibodies for use in detecting polymyxins and tracers; and to a single-capture immunodetection method and kits, each utilising the antibodies of the invention, and disclosed tracers. | 04-07-2016 |
Peter Fitzgerald, Antrim GB
Patent application number | Description | Published |
---|---|---|
20140004623 | Assay for Benzylpiperazine and Metabolites | 01-02-2014 |
20150126385 | BIOMARKER-BASED METHODS AND BIOCHIPS FOR AIDING THE DIAGNOSIS OF STROKE - The present invention provides biomarker-based methods for diagnosing stroke in a patient suspected of having suffered a stroke, and also for discriminating between ischemic stroke and transient ischemic attack. Substrates comprising probes for specific combinations of biomarkers useful in the methods of the invention are also described. | 05-07-2015 |
20160097780 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE - The present invention relates to methods for the diagnosis of subjects that have or are at risk of having Alzheimer's disease (AD). In particular the present invention identifies individuals who have or are at risk of having AD through measurement of the levels of Afamin in combination with at least one other biomarker such as Alpha-1-antichymotrypsin, Alpha-2-macroglobulin, ApoB100, Complement C5, Serine threonine protein kinase TBK1 or Complement C3 in a fluid sample taken from a subject. Furthermore, genotype (Apolipoprotein E or glutathione S-transferase Omega) may also be taken into consideration and used within classification algorithms to determine the probability of a subject having or being at risk of having AD. | 04-07-2016 |
Peter Fitzgerald, Co Antrim GB
Patent application number | Description | Published |
---|---|---|
20160139147 | Method for Aiding Differential Diagnosis of Stroke - The present invention provides a method of aiding the differential diagnosis of haemorrhagic stroke, ischemic stroke and a transient ischemic attack in a patient who has suffered or is suffering a stroke. The method comprises: (i) determining the concentration of the biomarkers VCAM-1, GFAP and CRP in an ex vivo sample obtained from the patient; and (ii) establishing the statistical significance of the concentration of the biomarkers. Optionally, the method further comprises steps of (iii) determining the concentration of the biomarkers IL-6 and sTNFR1 in an ex vivo sample obtained from the patient; (iv) determining the gender of the patient; and (v) establishing the statistical significance of the concentration of the five biomarkers, in conjunction with the patient's gender. The present invention also provides substrates comprising probes for VCAM-1, GFAP and CRP for use in a method for aiding the differential diagnosis of stroke. | 05-19-2016 |
Peter Fitzgerald, Northern Ireland GB
Patent application number | Description | Published |
---|---|---|
20130121878 | REAGENT BOTTLES, VALVES THEREFOR, WASHING MODULES AND METHODS AND APPARATUS FOR DISPENSING REAGENTS - A valve for a reagent bottle is provided, the valve including a resilient membrane configured to extend across an opening in the reagent bottle, the resilient membrane having at least one slit extending therethrough. Also disclosed is a dispensing apparatus for dispensing a reagent from a reagent bottle, the dispensing apparatus comprising: a probe assembly having a probe adapted for insertion into the reagent bottle through the valve and an extraction mechanism for drawing reagent out of the reagent bottle through the probe. A valve opening assembly is provided, which is adapted to open the valve of the reagent bottle such that the probe can pass through the valve without contacting the valve. | 05-16-2013 |
Peter Stephen Fitzgerald, Antrim GB
Patent application number | Description | Published |
---|---|---|
20120237947 | Glutathione S-Transferase Omega 1 Wild Type Specific Antibody - The invention relates to a novel antibody which binds to wild type (wt) Glutathione S-transferase Omega 1 (wtGSTO1) but not to mutant (mut) GSTO1 and methods and uses based on the antibody. The antibody is based on novel haptens and immunogens. | 09-20-2012 |
Peter Stephen Fitzgerald, Ardmore GB
Patent application number | Description | Published |
---|---|---|
20120322089 | SENSITIVE AND GENERIC ANTIBODIES AND MULTIPLE APPLICATIONS - The invention relates to the detection and quantification of carbamazepine drugs and their metabolites. The invention is underpinned by novel polyclonal antibodies with unique binding properties which enable immunoassay methods and kits for various applications. | 12-20-2012 |
Peter Stephen Fitzgerald, Crumlin GB
Patent application number | Description | Published |
---|---|---|
20150185241 | Tilidine Immunodetection - An immunoassay for the detection of tilidine and nortilidine is described. The invention also describes antibodies and kits. | 07-02-2015 |
Rebecca C. Fitzgerald, Swindon GB
Patent application number | Description | Published |
---|---|---|
20130065785 | PROGNOSIS OF OESOPHAGEAL AND GASTRO-OESOPHAGEAL JUNCTIONAL CANCER - The present invention relates to a method of aiding in the prognosis of a subject with oesophageal and/or gastro-oesophageal junctional (GOJ) adenocarcinoma, the method comprising the steps of: (a) providing a sample from the subject, (b) determining the expression level of biomarkers TRIM44 and SIRT2 in said sample, and either (i) determining the expression level of biomarker PAPPS2 in said sample; or (ii) determining the expression level of biomarkers WT1 and EGFR in said sample; (c) comparing the expression level of each of said biomarkers to a corresponding reference standard, (d) determining the biomarkers of (b) whose expression is dysregulated compared to the reference standard, (e) inferring from the dysregulated biomarkers identified in (d) the prognosis of 5-year survival, wherein the greater the number of said biomarkers which are dysregulated, the greater the reduction in prognosis of 5-year survival. The invention also relates to kits, uses and devices. | 03-14-2013 |
Richard Fitzgerald, Surrey GB
Patent application number | Description | Published |
---|---|---|
20080320203 | Memory Management in a Computing Device - A computing device incorporating memory such as mobile SDRAM, which is capable of conserving energy by being operated in a low-power self-refresh mode, is enabled to identify those regions of memory which are allocated but inactive. These regions are collected into specific banks of memory so as to create banks of memory containing only inactive data and which can then be placed in self-refresh. This reduces the power consumed by the computing device, and improves the energy efficiency of the device. | 12-25-2008 |
Richard Fitzgerald, Edinburgh GB
Patent application number | Description | Published |
---|---|---|
20110004719 | Memory Element - Disclosed is memory apparatus ( | 01-06-2011 |
20110060775 | FILE STORAGE METHOD AND SYSTEM - A method and system for storing files in a computer readable format using a file allocation table wherein a storage device is formatted with a single file allocation table when accessed by a system which includes means for reconstituting the file allocation table in the event of a failure. Also provided is a method for determining how many file allocation tables to write to a storage device based on a number of characteristics of the storage device such as type, data structure previously provided on the device etc, and/or on user input. | 03-10-2011 |
Richard Fitzgerald, London GB
Patent application number | Description | Published |
---|---|---|
20100262638 | Computing Device Having a Merged Directory Hierarchy From Multiple Filesystems - A computing device comprises a plurality of data images for controlling operation of the device, wherein each image contains an independent filesystem containing a directory hierarchy and file list applicable to the contents of that image, and in which the computing device additionally contains a single directory hierarchy and file list applicable to the entire body of embedded software. | 10-14-2010 |
Ross J. Fitzgerald, Edinburgh GB
Patent application number | Description | Published |
---|---|---|
20120282289 | STAPHYLOCOCCAL ANTIGENS - The present invention provides novel sequences encoding | 11-08-2012 |
Simon Fitzgerald, Warwick GB
Patent application number | Description | Published |
---|---|---|
20110239859 | SEAL FOR A PISTON ROD - A piston arrangement includes, but is not limited to a hydraulically-actuated piston to move a piston rod within a cylinder to pivot a clutch actuating lever, the end of the cylinder being sealed by a boot-type seal having a central hole, though which the rod slides in a reciprocating manner. The seal is flexible to permit transverse movements of the piston rod and has a peripheral flange by means of which it is attached to the cylinder end. | 10-06-2011 |
Stephen P. Fitzgerald, Co Antrim GB
Patent application number | Description | Published |
---|---|---|
20120135886 | METHOD FOR DETECTION OF, OR THE RISK OF, BLADDER CANCER - The present invention provides a method for the detection of or the risk of bladder cancer in a patient, comprising the step of detecting the presence of a combination of at least two biomarkers selected from CEA, VEGF, IL-8, NGAL, NSE, IL-2, EGF, TM, d-Dimer, MMP-9, IL-6, IL-4, MMP-9/NGAL, FAS, CRP, TUP and NMP22 in one or more samples isolated from a patient wherein the presence of a combination of at least two biomarkers in the one or more samples indicates the presence or risk of bladder cancer. | 05-31-2012 |
Stephen P. Fitzgerald, Crumlin GB
Patent application number | Description | Published |
---|---|---|
20100291600 | Immunoassay - The present invention provides an immunoassay method for detecting or determining the amount of salvinorin A, salvinorin B and/or analogues thereof in an in vitro sample, an antibody for salvinorin A, salvinorin B and/or analogues thereof and a kit for detecting the presence of or determining the amount of salvinorin A, salvinorin B and its analogues thereof in a sample. | 11-18-2010 |
20140072987 | METHODS OF DETECING BLADDER CANCER - The disclosure relates to methods of detecting bladder cancer including assaying a patient sample for the levels of certain combinations of biomarkers. The disclosure also relates to methods for determining the efficacy of a drug for the treatment of bladder cancer. | 03-13-2014 |
Stephen P. Fitzgerald, Antrim GB
Patent application number | Description | Published |
---|---|---|
20120142548 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND PROGNOSIS OF ALZHEIMER'S DISEASE - The invention relates to methods of diagnosing Alzheimer's disease (AD) in a subject and methods of determining the prognosis in patients with AD. The adhesion molecules P-selectin and L-selectin are described for the first time for use as biomarkers to aid in the diagnosis of AD. The invention further describes the use of one or more of L-selectin, MCP-1, IL-1α, IL-8 and IFN-γ to aid in the prognosis of either accelerated cognitive decline (ACD) or slow cognitive decline (SCD) in patients with AD. | 06-07-2012 |
Stephen Peter Fitzgerald, Crumlin GB
Patent application number | Description | Published |
---|---|---|
20110189794 | IMMUNOASSAY WITH EXTENDED DETECTION WINDOW - The immunoassay method and kit are provided for the detection and/or the determination of zolpidem. The disclosure provides novel antibodies, derived from a novel immunogen, that are highly sensitive and bind to zolpidem and its main urinary metabolite [3-(2-N,N-dimethylamino-2-oxoethyl)-6-methylimidazo[1,2-a]pyridin-2-yl]benzoic acid, enabling an extension of the detection window of zolpidem in individuals who have abused the drug, or have been victim of its side-effects or its criminal misuse. | 08-04-2011 |
20120135434 | MCPP IMMUNOASSAY - The invention describes a practical and robust multi-antibody approach to the sensitive immunodetection and determination of the drug of abuse m-chlorophenyl piperazine (mCPP). The invention also describes methods and kits for mCPP detection in an in vitro sample. | 05-31-2012 |
20120164756 | ASPIRIN ASSAY - The invention describes a method for monitoring and detecting non-therapeutic, therapeutic and toxic concentrations of aspirin in individuals which uses the urinary salicylic acid to salicyluric acid ratio. | 06-28-2012 |
20120208213 | Detection of Synthetic Cannabinoids - The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits. | 08-16-2012 |
20130065323 | Detection of Synthetic Cannabinoids - The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the CP family. Unique antibodies derived from novel immunogens enable said methods and kits. | 03-14-2013 |
20130196354 | Detection of Synthetic Cannabinoids - The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and RCS families. Unique antibodies derived from novel immunogens enable said methods and kits. | 08-01-2013 |
20140007676 | CAPACITIVE LIQUID LEVEL SENSOR - A capacitive liquid level sensor is provided comprising a capacitive probe having a capacitance and comprising a sensing tip wherein the capacitive probe is configured such that the capacitance of the probe changes when the sensing tip is exposed to liquid. A signal generator operates to supply an electrical signal alternating between a high and low state to the capacitive probe, the electrical signal being configured such that the probe is alternately charged and discharged when the signal is high or low respectively. A comparator operates to detect the magnitude of an electrical signal across the capacitive probe and provides a first output signal value when the detected signal magnitude is greater than a predetermined threshold value and a second output signal value when the signal magnitude is less than the threshold value. A timer operates to receive an output signal from the comparator and measures a time period starting when the comparator output signal transitions to the first output signal value and ending when the comparator output signal transitions to the second output signal value. Liquid detection means also operate to utilise the time period measured by the timer to determine if the sensing tip is exposed to liquid. | 01-09-2014 |
20150118763 | DETECTION OF SYNTHETIC CANNABINOIDS - The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits. | 04-30-2015 |
Stephen Peter Fitzgerald, Crumlin Antrim GB
Patent application number | Description | Published |
---|---|---|
20120208294 | IMMUNODETECTION AND QUANTIFICATION OF PYRAZOLOPYRIMIDINE SEDATIVES - The invention relates to novel immunogens, antibodies, methods and kits for use in immunoassays to detect and quantify zaleplon, metabolites of zaleplon and indiplon. These are the first described immunoassays for these compounds and have greater sensitivity than alternative analytical techniques. | 08-16-2012 |
20130310277 | MULTI-ANALYTE MICROARRAYS USING TAG-SPECIFIC ANTIBODIES AND TAG-ANCHORED ANTIBODIES - The invention describes accurate and flexible methods and kits for conducting multi-analyte microarrays through the use of Tag-specific antibodies and analyte-specific Tag-anchored antibodies. | 11-21-2013 |
Stephen Peter Fitzgerald, Co. Antrim GB
Patent application number | Description | Published |
---|---|---|
20090311671 | Diagnosis of risk of breast cancer - A diagnostic method is disclosed which can he used to predict the risk of cancer, in particular breast cancer. The method comprises: (i) isolating a sample of the patient's genome: and (ii) detecting the presence or expression of the gene comprised within the sequence identified herein as SEQ ID No. 1, wherein the presence or expression of the gene indicates the presence of or the risk of cancer. | 12-17-2009 |
Stephen Peter Fitzgerald, Northern Ireland GB
Patent application number | Description | Published |
---|---|---|
20100047770 | Detection of Breast Cancer - A method for the detection of the presence or risk of cancer in a patient, comprises the steps of: (i) isolating a sample of the patient's genome; and (ii) detecting the presence or expression of the gene characterized by any of the nucleotide sequences identified as SEQ ID No 1, SEQ ID No. 10 and SEQ ID No. 13 wherein the presence or expression of the gene indicates the presence of or the risk of cancer. | 02-25-2010 |
20150219670 | KIDNEY DISEASE BIOMARKER - The present invention provides a method of stratifying a patient suffering from CKD into one of stages 1-3 of CKD, comprising determining the level of the biomarkers FABP1, γ-GT, AST, creatinine and cystatin C in a sample obtained from the patient and comparing the level of FABP1 in the sample to a control value and the levels of γ-GT, AST, creatinine and cystatin C in the sample to a range of control values for each biomarker, wherein an increased level of FABP1 compared to the control value and levels of γ-GT, AST, creatinine and cystatin C within the range of control values for each biomarker indicate that the patient suffers from stage 1 CKD or wherein an increased level of FABP1 compared to the control value, levels of γ-GT and AST within the range of control values for each biomarker, and increased levels of creatinine and cystatin C compared to an upper threshold of the control range for these biomarkers indicate that the patient suffers from stage 2 or stage 3 CKD. | 08-06-2015 |
Timothy Charles Andrew Fitzgerald, Godalming GB
Patent application number | Description | Published |
---|---|---|
20160050890 | Charging a Device Supported by an Animal - The charging of an electrical device ( | 02-25-2016 |