Frey, CH
Alexander-Daniel Frey, Olten CH
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20110207214 | NOVEL TOOLS FOR THE PRODUCTION OF GLYCOSYLATED PROTEINS IN HOST CELLS - The invention improves glycoprotein production and protein glycosylation engineering in eukaryotes, specifically the production of human-like complex or hybrid glycosylated proteins in lower eukaryotes such as yeasts. The invention provides glycosylation modified eukaryotic host cells capable of producing glycosylation optimized proteins useful as immunoglobulins and other therapeutic proteins, and provides cells capable of producing glycoproteins having glycan structures similar to glycoproteins produced in human cell. The invention further provides proteins with human-like glycan structures and novel compositions thereof producible by these cells. | 08-25-2011 |
Bernhard Frey, Schaffhusen CH
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20100119394 | CYLINDER PISTON ARRANGEMENT FOR A FLUID PUMP OR A FLUID MOTOR - The invention relates to a cylinder piston arrangement for an especially volumetric fluid pump or a fluid motor, preferably comprising at least one axial expansion tubular membrane piston defining at least one inner pulsating working chamber. A particular field of application for such pumps or motors is the operation thereof with fluids loaded with extraneous materials, especially abrasive granulated materials. Especially high-speed machines with high working pressures of between a few hundred to a thousand bar are required, the energetic and also volumetric degree of efficiency thus becoming highly important factors. The aim of the invention is therefore to create pumps or fluid motors which are characterised by high degrees of efficiency and long service lives. To this end, at least one clearance driving body (TK | 05-13-2010 |
Brigitte Frey, Bolligen CH
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20150190534 | COMPOUNDS FOR USE AS POSITRON EMISSION IMAGING AGENTS - The present invention relates generally to compounds according to formula I that bind more specifically to mutated androgen receptors than to the wild type androgen receptors and therefore are useful as imaging agents for positron emission tomography (PET) used in the diagnosis and monitoring of prostate cancer. | 07-09-2015 |
Christian Frey, Unteraegeri CH
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20140222329 | DYNAMIC EMERGENCY AID - Dynamic output of information for the evacuation of persons, in particular from buildings, is provided to a portable device based on current position data of the device as determined by a position determination system. The current usability of escape routes located in the building is determined by a sensor system. Evacuation information is determined by a control unit, based on the current usability of the escape routes and the current position of the device and output on the portable device. In emergency situations, dedicated evacuation information can thus be determined for a person as a function of the whereabouts of the person and the respective hazardous situation and output on the mobile device (e.g. smartphone, PDA) of the person. This enables, inter alia, a rapid and efficient evacuation of the building or a site. | 08-07-2014 |
Christian Frey, Niedergoesgen CH
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20100115279 | Method for pairing and authenticating one or more medical devices and one or more remote electronic devices - A method for authenticating a medical device and a remote electronic device may include generating a PIN code by one device, capturing the generated PIN code with the other device, checking authentication of the PIN code, which is based at least in part on the captured PIN code, by the one device, generating a strong key by the one device, sending the strong key encrypted to the other device, checking authentication of the sent strong key by the one device, and upon successful authentication, storing the strong key in a memory of the one device and the other device. The roles of the medical device and the remote electronic device may be reversed in the authenticating method. The authenticating method may be preceded by a pairing process and/or followed by a binding process. | 05-06-2010 |
Christof Frey, Hunzenschwil CH
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20110249787 | FILTER CHANGING ASSEMBLY FOR FILTERING A RADIATION BEAM - A filter changing assembly that can be used in, for example, a radiology system includes shape filters that can used to shape a radiation beam and that can be moved back-and-forth, for example. The filter changing assembly also includes beam hardening filters that can be used to change the energy spectrum of the radiation beam, and that also can be moved back-and-forth, for example. The filter changing assembly includes a control system that can be used to select at least one of the filters and automatically move the selected filter from one position to another position. | 10-13-2011 |
20130111668 | Couch Top Pitch and Roll Motion by Linear Wedge Kinematic and Universal Pivot - A couch top includes a top, a base, a universal joint coupling the top and the base, and actuators mounted on the base to pitch and roll the top. Feedback devices may be fitted on the rotating ends of the universal joint to provide feedback for a control loop. Each actuator has an actuated end that translates vertically to lift or lower the top. The vertical movement may be derived from a carriage riding in place on a translating inclined plane. When the actuated ends move in the same direction, they pitch the top. When the actuated ends move in the opposite directions, they roll the top. Feedback devices may be fitted on motors in the actuators to provide feedback for the control loop. | 05-09-2013 |
Ernst M. Frey, Sigriswil CH
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20100055309 | INTERNAL WELD SEAM PROTECTION FOR CANS - According to the invention, a continuous protective film ( | 03-04-2010 |
Felix Frey, Kriechenwil CH
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20110034852 | IMPLANTABLE ACCESS FOR REMOVAL AND/OR RETURN OF FLUIDS - Implantable access device for removal and/or return of fluids to a patient, comprising a casing attached to an internal conduit to be connected with a lumen of the patient; a connector attached at the casing and connected to an external conduit, and arranged for attachment of an extracorporeal lumen to the device; and an actuator unit within the casing to selectively allow or block the fluid communication between the internal conduit and the external conduit; the device further comprising a fixation unit integrated in or attached at the casing arranged for fixation of the device to a bone of the patient; wherein the fixation unit extends axially along the longitudinal axis of the device. The disclosed access device can be used for high volume removal and/or return of blood or other fluids from the patient. | 02-10-2011 |
20120116316 | METHOD FOR IMPLANTING AN ACCESS PORT - A transcutaneous access port to a user has a coupling member destined to be anchored in a bone of the user. A first valve system is removably connectable to the coupling member and a second valve system is removably connected to the first valve system. An internal conduit is connected at its proximal end to the access port and at its distal end to a vascular structure of the user. An external conduit is connected to the access port and to an extracorporeal device. A traversing cavity is formed in the bone at an implantation site of the user, passing the internal conduit. The internal conduit is routed through the traversing cavity to connect its distal end to the vascular structure of the user. The coupling member is anchored to the bone at the implantation site. The proximal end of the internal conduit is connected to the access port. | 05-10-2012 |
20120157924 | IMPLANTABLE VASCULAR ACCESS - A transcutaneous implantable access port for removal and/or return of fluids of a patient comprises a fixation unit adapted to be fixed to a bone of the patient; a valve unit comprising a sealing membrane at its distal end and one or more chambers; an internal conduit fluidly connectable to vascular structure of the patient and releasably connectable to the valve unit to establish fluidic communication between the internal conduit and said one or more chambers; and an extracorporeal connecting member having an end portion. The extracorporeal connecting member is connectable to the distal end of the valve unit, opening and closing a fluidic passage between the connecting member and said one or several chambers when the connecting member is respectively connected to the access port and withdrawn therefrom. The access port can be used for high volume removal and/or return of blood or other fluids from the patient. | 06-21-2012 |
20130072847 | IMPLANTED ACCESS PORT - Implantable access port for removal and/or return of fluids to a patient, comprising an internal conduit connectable at its proximal end to the access port and at its distal end to a vascular structure of the patient; an external conduit connectable at its proximal end to the access port and at its distal end to an extracorporeal device; and a transcutaneous coupling member destined to be anchored in a tissue of the patient and comprising a first valve system operable to be in an open or closed configuration; the coupling member further comprises a second valve system removably connectable to the first valve system and operable to be in an open or closed configuration, such as to establish fluid communication between the internal and external conduits when the first and second valve systems are connected and in open configuration. | 03-21-2013 |
Joachim Frey, Bern CH
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20090074817 | TYPE III SECRETION PATHWAY IN AEROMONAS SALMONICIDA, AND USES THEREFOR - Disclosed is a newly identified and characterized type III secretion system in | 03-19-2009 |
20100008895 | NOVEL EXOENZYME TOXIN OF AEROMONAS SALMONICIDA, AND USES THEREFOR - A protein toxin named | 01-14-2010 |
20110280900 | CLOSTRIDIUM CHAUVOEI POLYPEPTIDE, DNA ENCODING THE POLYPEPTIDE AND A VACCINE COMPRISING THE POLYPEPTIDE - The present invention pertains to the identification and initial characterization of CctA, a novel, secreted toxin of | 11-17-2011 |
Markus Frey, Rheinfelden CH
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20090069470 | Process for the synthesis of n-alkoxyamines - The present invention relates to novel processes for the preparation of a sterically hindered amine ethers by the transformation of a corresponding oxo-piperidin to a hydroxy or amino substituted sterically hindered amine ether and the preparation of a N-propoxy or N-propenoxy substituted sterically hindered amine and some novel compounds obtainable by these processes. The compounds made by these processes are particularly effective in the stabilization of polymer compositions against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers. | 03-12-2009 |
20090274947 | Imidazolidinone nitroxides as electrode materials for energy storage devices - The invention relates to a an electrical energy storage device, such as a capacitor or a secondary battery, utilizing as active element the oxidation and reduction cycle of a sterically hindered imidazolidinone nitroxide radical. Further aspects of the invention are a method for providing such an energy storage device, the use of the respective compounds as active elements in energy storage devices and selected novel imidazolidinone nitroxide compounds. | 11-05-2009 |
20090318592 | Process for the Synthesis of Amine Ethers - The present invention relates to novel processes for the preparation of a sterically hindered amine ether by reacting a corresponding sterically hindered amine oxide with a ketone or an aldehyde with at least one reactive H in the presence of a peroxydisulphate. Products obtained by this process may be hydrogenated. The compounds made by these processes are particularly effective in the stabilization of polymer compositions against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers. | 12-24-2009 |
20100143805 | NITROXIDES FOR LITHIUM-ION BATTERIES - This invention relates to overcharge protection and molecular redox shuttles in rechargeable lithium-ion cells. For this, specific nitroxyls or oxoammonium salts are used in the electrolyte. This invention also relates to a method of producing such lithium-ion cells and to a method of recharging such lithium-ion cells. This invention also pertains to some nitroxyls compounds and oxoammonium salts. | 06-10-2010 |
20100178512 | CHANGING SURFACE PROPERTIES BY FUNCTIONALIZED NANOPARTICLES - A process for modifying the surface of an inorganic or organic substrate with strongly adherent nanoparticles is described, providing to the surface modified substrate durable effects like hydrophobicity, hydrophilicity, electrical conductivity, magnetic properties, flame retardance, color, adhesion, roughness, scratch resistance, UV-absorbance, antimicrobial properties, antifouling properties, antiprotein properties, antistatic properties, antifog properties, release properties. In this process, an optional first step a) a low-temperature plasma, ozonization, high energy irradiation, corona discharge or a flame is caused to act on the inorganic or organic substrate, and in a second step b) one or more defined nanoparticles or mixtures of defined nanoparticles with monomers, containing at least one ethylenically unsaturated group, or solutions, suspensions or emulsions of the afore-mentioned substances, are applied, preferably at normal pressure, to the inorganic or organic substrate. In a third step c) suitable methods are applied to dry or cure those afore-mentioned substances and, optionally, in a fourth step d) a further coating is applied on the substrate so pretreated. | 07-15-2010 |
20110015315 | PROCESS FOR THE SYNTHESIS OF N-ALKOXYAMINES - The present invention relates to novel processes for the preparation of sterically hindered amine ethers by the transformation of a corresponding oxo-piperidin to a hydroxy or amino substituted sterically hindered amine ether and the preparation of a N-propoxy or N-propenoxy substituted sterically hindered amine and some novel compounds obtainable by these processes. The compounds made by these processes are particularly effective in the stabilization of polymer compositions against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers. | 01-20-2011 |
20120142793 | SILSESQUIOXANE PHOTOINITIATORS - Photoinitiator compounds comprising both a photoactive moiety and an amine functionality, bonded to a polyhedral oligomeric silsesquioxane, which photoinitiator is represented by formula (1) or (1′) wherein n is 2m; m is an integer of 2 to 30; the sum of n′+a is an integer 4-60; n′ is an even-numbered integer; a is an even- or uneven-numbered integer; and for example different A C | 06-07-2012 |
20120178844 | MACROPHOTOINITIATORS - The invention pertains to high-molecular photoinitiator compounds comprising a photoactive moiety Q and an amine functionality, preferably a tertiary amino group, where the photoactive moiety Q is a benzoyl photoactive moiety. | 07-12-2012 |
20130041148 | PROCESS FOR THE SYNTHESIS OF N-ALKOXYAMINES - The present invention relates to novel processes for the preparation of sterically hindered amine ethers by the transformation of a corresponding oxo-piperidin to a hydroxy or amino substituted sterically hindered amine ether and the preparation of a N-propoxy or N-propenoxy substituted sterically hindered amine and some novel compounds obtainable by these processes. The compounds made by these processes are particularly effective in the stabilization of polymer compositions against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers. | 02-14-2013 |
20130117941 | METAL FREE BLEACHING COMPOSITION - The present invention relates to the use of a composition comprising specific a-amino-ketones, H | 05-16-2013 |
20150031879 | PROCESS FOR THE SYNTHESIS OF N-ALKOXYAMINES - The present invention relates to novel processes for the preparation of sterically hindered amine ethers by the transformation of a corresponding oxo-piperidin to a hydroxy or amino substituted sterically hindered amine ether and the preparation of a N-propoxy or N-propenoxy substituted sterically hindered amine and some novel compounds obtainable by these processes. The compounds made by these processes are particularly effective in the stabilization of polymer compositions against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers. | 01-29-2015 |
Matthias O. Frey, Zurich CH
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20160092771 | ANALYSIS OF SOCIAL MEDIA MESSAGES - In a method for analyzing social media messages, the method includes one or more processors analyzing social media messages utilizing a set of topics and keywords associated with a brand. The method further includes one or more processors identifying social media messages that include information relating to the brand utilizing the analysis of social media messages utilizing the set of topics and keywords. The method further includes one or more processors determining relevancy scores for the identified social media messages that provide an indication of the percentage likelihood that a social media message is related to the brand. The method further includes one or more processors determining one or more recommendations of social media users associated with social media messages based on the determined relevancy scores. | 03-31-2016 |
Nicolas Frey, Lausanne CH
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20140215855 | Sports Boot - Sports boot comprising: an inner boot ( | 08-07-2014 |
Patrick Frey, Oberdiessbach CH
Philip Frey, Uerikon CH
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20110270943 | ZERO COPY DATA TRANSMISSION IN A SOFTWARE BASED RDMA NETWORK STACK - A method for data transmission on a device without intermediate buffering is provided. An application request is received to transmit data from the device to a second device over a network. The data from application memory is formatted for transmitting to the second device. The data are transmitted from the device to the second device without intermediate buffering. A send state is retrieved. The send state is compared to expected send state. If the send state meets the expected send state, a completion of the data transmit request is generated. | 11-03-2011 |
20120131124 | RDMA READ DESTINATION BUFFERS MAPPED ONTO A SINGLE REPRESENTATION - A computer-implemented method, system, and article of manufacture for data communication between a requester and a responder in a remote direct memory access (RDMA) network, where each of the requester and the responder is an RDMA-enabled host of the network. The method includes: sending a request for the responder to provide data, where the request includes a mapped steering tag that is obtained by mapping a set of memory buffers of the requester onto a single representation that allows for identifying each of the memory buffers of the set; and receiving the requested data together with the mapped steering tag and assigning the data being received to the memory buffers of the set consistently with the mapping. | 05-24-2012 |
Philip W. Frey, Rueschlikon CH
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20110106905 | DIRECT SENDING AND ASYNCHRONOUS TRANSMISSION FOR RDMA SOFTWARE IMPLEMENTATIONS - Exemplary embodiments include RDMA methods and systems for sending application data to a computer memory destination in a direct but non-blocking fashion. The method can include posting a new work request for an RDMA connection or association, determining if there is a prior work request for the same connection or association enqueued for processing, in response to a determination that no prior work request is enqueued for processing, processing the new work request directly by sending RDMA frames containing application data referred to by the work request to the computer memory destination, performing direct sending while there is sufficient send space to process the new work request, and delegating the new work request to asynchronous transmission if a prior work request is already enqueued for processing or lack of send space would block a subsequent transmission operation. | 05-05-2011 |
Rolf Frey, Ebikon CH
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20100028203 | Laboratory system for handling sample tube racks, an alignment element for sample tube racks and a rack tray receiver assembly - A laboratory system for handling sample tube racks, an alignment element for sample tube racks and a rack tray receiver assembly are disclosed. The laboratory system to handle laboratory sample tube racks comprises a robotic arm ( | 02-04-2010 |
20130017535 | INSTRUMENT AND PROCESS FOR THE AUTOMATED PROCESSING OF LIQUID SAMPLESAANM Frey; RolfAACI EbikonAACO CHAAGP Frey; Rolf Ebikon CHAANM Schacher; GottliebAACI KriensAACO CHAAGP Schacher; Gottlieb Kriens CH - An automated instrument and process for processing samples is presented. The instrument comprises a sampling area for receiving samples and reaction vessels; an analytical area with a first device resource comprising at least one analyzer; a reaction area comprising a conveyor for reagent containers; an incubator; a second device resource comprising first functional devices, the first functional devices having access to the sampling area and the incubator such as to transfer reaction vessels from the sampling area to the incubator and/or to pipette samples and/or reagents into the reaction vessels; a third device resource comprising second functional devices, the second functional devices having access to the incubator and the analytical area such as to transfer the reaction vessels from the incubator to the analytical area and/or to dispense liquids or withdraw liquids from the reaction vessels. | 01-17-2013 |
20140037420 | Laboratory system for handling sample tube racks, an alignment element for sample tube racks and a rack tray receiver assembly - A laboratory system for handling sample tube racks, an alignment element for sample tube racks and a rack tray receiver assembly are disclosed. The laboratory system to handle laboratory sample tube racks comprises a robotic arm ( | 02-06-2014 |
Urs Frey, Zurich CH
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20120230097 | DETERMINING CELL-STATE IN PHASE-CHANGE MEMORY - A method, an apparatus, and a device for determining the state of a phase-change memory cell. The method includes the steps of: biasing a cell with a time-varying read voltage (V | 09-13-2012 |
20120230098 | PROGRAMMING OF PHASE-CHANGE MEMORY CELLS - A method and apparatus for programming a phase-change memory cell. A bias voltage signal (V | 09-13-2012 |
20120307554 | DETERMINING CELL-STATE IN PHASE-CHANGE MEMORY - A method, an apparatus, and a device for determining the state of a phase-change memory cell. The method includes the steps of: biasing a cell with a time-varying read voltage (V | 12-06-2012 |
20120327709 | PROGRAMMING OF PHASE-CHANGE MEMORY CELLS - A method and apparatus for programming a phase-change memory cell. A bias voltage signal (V | 12-27-2012 |