Patent application number | Description | Published |
20120322078 | Production of Propanols, Alcohols, and Polyols in Consolidated Bioprocessing Organisms - The present invention provides for novel metabolic pathways leading to propanol, alcohol or polyol formation in a consolidated bioprocessing system (CBP), where lignocellulosic biomass is efficiently converted to such products. More specifically, the invention provides for a recombinant microorganism, where the microorganism expresses one or more native and/or heterologous enzymes; where the one or more enzymes function in one or more engineered metabolic pathways to achieve: (1) conversion of a carbohydrate source to 1,2-propanediol, isopropropanol, ethanol and/or glycerol; (2) conversion of a carbohydrate source to n-propanol and isopropanol; (3) conversion of a carbohydrate source to isopropanol and methanol; or (4) conversion of a carbohydrate source to propanediol and acetone; wherein the one or more native and/or heterologous enzymes is activated, up-regulated or down-regulated. | 12-20-2012 |
20130273555 | Detoxification of Biomass Derived Acetate Via Metabolic Conversion to Ethanol, Acetone, Isopropanol, or Ethyl Acetate - One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce lactate or acetate as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non-native gene encodes a first non-native enzyme involved in the metabolic production of lactate or acetate. Another aspect of the invention relates to a process for converting lignocellulosic biomass to lactate or acetate, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism. | 10-17-2013 |
20130323822 | Yeast Expressing Saccharolytic Enzymes for Consolidated Bioprocessing Using Starch and Cellulose - The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting strain, or strains can be used to hydrolyze starch and cellulose simultaneously. The resulting strain, or strains can be also metabolically engineered to produce less glycerol and uptake acetate. The resulting strain, or strains can also be used to produce ethanol from granular starch without liquefaction. The resulting strain, or strains, can be further used to reduce the amount of external enzyme needed to hydrolyze a biomass feedstock during an Simultaneous Saccharification and Fermentation (SSF) process, or to increase the yield of ethanol during SSF at current saccharolytic enzyme loadings. In addition, multiple enzymes of the present invention can be co-expressed in cells of the invention to provide synergistic digestive action on biomass feedstock. In some aspects, host cells expressing different heterologous saccharolytic enzymes can also be co-cultured together and used to produce ethanol from biomass feedstock. | 12-05-2013 |
20140308724 | Yeast Expressing Saccharolytic Enzymes for Consolidated Bioprocessing Using Starch and Cellulose - The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting strain, or strains can be used to hydrolyze starch and cellulose simultaneously. The resulting strain, or strains can be also metabolically engineered to produce less glycerol and uptake acetate. The resulting strain, or strains can also be used to produce ethanol from granular starch without liquefaction. The resulting strain, or strains, can be further used to reduce the amount of external enzyme needed to hydrolyze a biomass feedstock during an Simultaneous Saccharification and Fermentation (SSF) process, or to increase the yield of ethanol during SSF at current saccharolytic enzyme loadings. In addition, multiple enzymes of the present invention can be co-expressed in cells of the invention to provide synergistic digestive action on biomass feedstock. In some aspects, host cells expressing different heterologous saccharolytic enzymes can also be co-cultured together and used to produce ethanol from biomass feedstock. | 10-16-2014 |
20160068850 | YEAST EXPRESSING SACCHAROLYTIC ENZYMES FOR CONSOLIDATED BIOPROCESSING USING STARCH AND CELLULOSE - The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting strain, or strains can be used to hydrolyze starch and cellulose simultaneously. The resulting strain, or strains can be also metabolically engineered to produce less glycerol and uptake acetate. The resulting strain, or strains can also be used to produce ethanol from granular starch without liquefaction. The resulting strain, or strains, can be further used to reduce the amount of external enzyme needed to hydrolyze a biomass feedstock during an Simultaneous Saccharification and Fermentation (SSF) process, or to increase the yield of ethanol during SSF at current saccharolytic enzyme loadings. In addition, multiple enzymes of the present invention can be co-expressed in cells of the invention to provide synergistic digestive action on biomass feedstock. In some aspects, host cells expressing different heterologous saccharolytic enzymes can also be co-cultured together and used to produce ethanol from biomass feedstock. | 03-10-2016 |
Patent application number | Description | Published |
20120200694 | MULTI-MODALITY CONTRAST AND BRIGHTFIELD CONTEXT RENDERING FOR ENHANCED PATHOLOGY DETERMINATION AND MULTI-ANALYTE DETECTION IN TISSUE - Multiple modality contrast can be used to produce images that can be combined and rendered to produce images similar to those produced with wavelength absorbing stains viewed under transmitted white light illumination. Images obtained with other complementary contrast modalities can be presented using engineered color schemes based on classical contrast methods used to reveal the same anatomical structures and histochemistry, thereby providing relevance to medical training and experience. Dark-field contrast images derived from refractive index and fluorescent DAPI counterstain images are combined to produce images similar to those obtained with conventional H&E staining for pathology interpretation. Such multi-modal image data can be streamed for live navigation of histological samples, and can be combined with molecular localizations of genetic DNA probes (FISH), sites of mRNA expression (mRNA-ISH), and immunohistochemical (IHC) probes localized on the same tissue sections, used to evaluate and map tissue sections prepared for imaging mass spectrometry. | 08-09-2012 |
20130122516 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY - Particular disclosed embodiments disclosed herein concern using a one or more various mass tags, which can be specifically deposited at targets through direct or indirect enzymatic-catalyzed transformation, to provide a method for identifying targets in tissue samples. The mass tags may be labeled with stable isotopes to produce mass tags having the same chemical structure but different masses. Mass codes produced by ionizing the mass tags are detected and/or quantified using mass spectrometry. The method can be used for multiplexed detection of multiple targets in a particular sample. In some embodiments, a map divided into sections representing sections of the tissue sample may be prepared, with the map sections including data corresponding to quantification data wherein the size of a mass peak is determined and correlated with the amount of a target for the corresponding tissue sample section. | 05-16-2013 |
20160139143 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY - Particular disclosed embodiments disclosed herein concern using a one or more various mass tags, which can be specifically deposited at targets through direct or indirect enzymatic-catalyzed transformation, to provide a method for identifying targets in tissue samples. The mass tags may be labeled with stable isotopes to produce mass tags having the same chemical structure but different masses. Mass codes produced by ionizing the mass tags are detected and/or quantified using mass spectrometry. The method can be used for multiplexed detection of multiple targets in a particular sample. In some embodiments, a map divided into sections representing sections of the tissue sample may be prepared, with the map sections including data corresponding to quantification data wherein the size of a mass peak is determined and correlated with the amount of a target for the corresponding tissue sample section. | 05-19-2016 |
Patent application number | Description | Published |
20090066234 | LIGHT EMITTING DEVICES AND COMPOSITIONS - A light emitting composition includes a light-emitting iridium-functionalized nanoparticle, such as an organic-inorganic light-emitting iridium-functionalized nanoparticle. A light emitting device includes an anode, a cathode, and a layer containing such a light-emitting composition. In an embodiment, the light emitting device can emit white light. | 03-12-2009 |
20090179552 | LIGHT EMITTING DEVICES AND COMPOSITIONS - A light emitting composition includes a light-emitting lumophore-functionalized nanoparticle, such as an organic-inorganic light-emitting lumophore-functionalized nanoparticle. A light emitting device includes an anode, a cathode, and a layer containing such a light-emitting composition. In an embodiment, the light emitting device can emit white light. | 07-16-2009 |
20120273765 | LIGHT EMITTING DEVICES AND COMPOSITIONS - A light emitting composition includes a light-emitting lumophore-functionalized nanoparticle, such as an organic-inorganic light-emitting lumophore-functionalized nanoparticle. A light emitting device includes an anode, a cathode, and a layer containing such a light-emitting composition. In an embodiment, the light emitting device can emit white light. | 11-01-2012 |
20120305895 | LIGHT EMITTING DEVICES AND COMPOSITIONS - A light emitting composition includes a light-emitting iridium-functionalized nanoparticle, such as a compound of formula (I). The compound of formula (I) further comprises at least one host attached to the core. A light emitting device includes an anode, a cathode, and a layer containing such a light-emitting composition is also disclosed. In an embodiment, the light emitting device can emit white light. | 12-06-2012 |
Patent application number | Description | Published |
20090208398 | NANOPARTICLE SYNTHESIS BY SOLVOTHERMAL PROCESS - A solvothermal process for making inorganic nanoparticles is described. Inorganic nanoparticles can be produced by forming a suspension or solution comprising at least one group II-IV and lanthanide metal inorganic salt in a first medium, disposing the suspension or solution in a sealed chamber having an interior pressure, elevating the interior pressure of the sealed chamber to an initial interior pressure prior to the heating, heating the suspension or solution to a peak temperature higher than the normal boiling point of the first medium, optionally adding a second medium to the suspension or solution after the heating. | 08-20-2009 |
20100283377 | NANOPARTICLE SYNTHESIS BY SOLVOTHERMAL PROCESS - An optical film capable of converting blue light to yellow light and a while light emitting device comprising the optical film are described. The optical film comprises a layer of YAG nanoparticles, wherein the layer of YAG nanoparticles has a size distribution of between about 2 nm to about 200 nm | 11-11-2010 |
20110193075 | PRINTABLE LIGHT-EMITTING COMPOSITIONS - Disclosed herein are compositions comprising an electron transport compound, an emissive compound, and an organic solvent. The emissive compound comprises an organic indium complex attached to a nanoparticle core. These compositions are useful in fabricating light emitting devices and can be deposited on a substrate via a printing process. | 08-11-2011 |
20130087772 | EMISSIVE COMPOUNDS FOR ORGANIC LIGHT-EMITTING DIODES - Disclosed herein are compounds comprising an optionally substituted (2-phenylpyridinato-N,C2′)(2,4-pentanedionato)Pt(II). Some embodiments provide a light-emitting device, comprising: an anode layer; a cathode layer; and a light-emitting layer positioned between, and electrically connected to, the anode layer and the cathode layer, wherein the light-emitting layer comprises a compound disclosed herein. | 04-11-2013 |
Patent application number | Description | Published |
20100313958 | SENSING EVENTS AFFECTING LIQUID FLOW IN A LIQUID DISTRIBUTION SYSTEM - By monitoring pressure transients in a liquid within a liquid distribution system using only a single sensor, events such as the opening and closing of valves at specific fixtures are readily detected. The sensor, which can readily be coupled to a faucet bib, transmits an output signal to a computing device. Each such event can be identified by the device based by comparing characteristic features of the pressure transient waveform with previously observed characteristic features for events in the system. These characteristic features, which can include the varying pressure, derivative, and real Cepstrum of the pressure transient waveform, can be used to select a specific fixture where a valve open or close event has occurred. Flow to each fixture and leaks in the system can also be determined from the pressure transient signal. A second sensor disposed at a point disparate from the first sensor provides further event information. | 12-16-2010 |
20140026644 | Sensing Events Affecting Liquid Flow in a Liquid Distribution System - By monitoring pressure transients in a liquid within a liquid distribution system using only a single sensor, events such as the opening and closing of valves at specific fixtures are readily detected. The sensor, which can readily be coupled to a faucet bib, transmits an output signal to a computing device. Each such event can be identified by the device based by comparing characteristic features of the pressure transient waveform with previously observed characteristic features for events in the system. These characteristic features, which can include the varying pressure, derivative, and real Cepstrum of the pressure transient waveform, can be used to select a specific fixture where a valve open or close event has occurred. Flow to each fixture and leaks in the system can also be determined from the pressure transient signal. A second sensor disposed at a point disparate from the first sensor provides further event information. | 01-30-2014 |
Patent application number | Description | Published |
20140276766 | ABLATION SYSTEM, METHODS, AND CONTROLLERS - Multi-electrode ablation systems, methods, and controllers are described. In one example, a multi-electrode ablation system generally includes a power supply and a controller. The power supply is configured to be coupled to a plurality of electrodes for delivering power to the electrodes. The controller is operable to compare a measured temperature at each electrode to a desired temperature to thereby define a temperature difference for each electrode. The controller is operable to determine, based on the temperature difference, a desired power for each electrode, compare the desired power of one of the electrodes to an actual power delivered to the one of the electrodes to define a power difference, and adjust the actual power delivered by the power supply to the one of the electrodes based on the power difference. | 09-18-2014 |
20140276767 | ABLATION SYSTEM, METHODS, AND CONTROLLERS - In a multi-electrode ablation system, method, and controller, a power supply is configured to be coupled to a plurality of electrodes, and a controller is coupled to the power supply. The controller is configured to couple an output voltage of the power supply to the plurality of electrodes, and for each electrode of the plurality of electrodes, measure a temperature associated with the electrode, and determine a thermal gain of each electrode of the plurality of electrodes. | 09-18-2014 |
20140276773 | ABLATION SYSTEM, METHODS, AND CONTROLLERS - In a multi-electrode ablation system, method, and controller, the controller is configured to measure a first current through a common return path when a first voltage is applied by a power supply to a first electrode of a plurality of electrodes, measure a second current through the common return path when a second voltage is applied by the power supply to a second electrode of the plurality of electrodes, measure a third current through the common return path when a third voltage is applied by the power supply concurrently to the first electrode and the second electrode, and determine a common path impedance based at least in part on the first voltage and the first current, the second voltage and the second current, and the third voltage and the third current. | 09-18-2014 |
20140316400 | ABLATION SYSTEM, METHODS, AND CONTROLLERS - Multi-electrode ablation systems, methods, and controllers are described. In one example, a method of beginning an ablation procedure using a multi-electrode ablation system is described. The method includes selectively coupling the output of a power supply to a first electrode of a plurality of electrodes to increase a temperature at the first electrode to a first temperature set-point and limit a rate of increase of the temperature at the first electrode to a predetermined first rate. | 10-23-2014 |
Patent application number | Description | Published |
20100263734 | METHODS AND SYSTEM FOR COOLING A REACTION EFFLUENT GAS - In one embodiment, a method for cooling a reaction effluent gas includes feeding a sufficient amount of a suitable silicon source cooling gas into a stream of the reaction effluent gas, wherein the reaction effluent gas is produced by a thermal decomposition of at least one silicon source gas in a reactor, and wherein sufficient amount of the suitable silicon source cooling gas is defined based a concentration of the at least one chemical species in the reaction effluent gas; cooling the reaction effluent gas to a sufficient temperature so that: the cooled reaction effluent gas is capable of being handled by a material that is not suitable for handling the reaction effluent gas. | 10-21-2010 |
20100266466 | REACTOR WITH SILICIDE-COATED METAL SURFACES - In an embodiment, a reactor includes a section, wherein at least a portion of the section includes a base layer, wherein the base layer has a first composition that contains a silicide-forming metal element; and a silicide coating layer, wherein the silicide coating layer is formed by a process of exposing, at a first temperature above 600 degrees Celsius and a sufficient low pressure, the base layer having a sufficient amount of the silicide-forming metal element to a sufficient amount of a silicon source gas having a sufficient amount of silicon element, wherein the silicon source gas is capable of decomposing to produce the sufficient amount of silicon element at a second temperature below 1000 degrees Celsius; reacting the sufficient amount of the silicide-forming metal element with the sufficient amount of silicon element, and forming the silicide coating layer. | 10-21-2010 |
20100273010 | Silicide-coated metal surfaces and methods of utilizing same - In an embodiment, a surface of the present invention comprises of at least one base layer, wherein the at least one base layer contains at least one silicide-forming metal element; and at least one silicide coating layer, wherein the at least one silicide coating layer is formed by a process of: i) exposing the at least one base layer having a sufficient amount of the at least one silicide-forming metal element to a sufficient amount of at least one silicon source gas having a sufficient amount of silicon element, ii) reacting the sufficient amount of the at least one silicide-forming metal element with the sufficient amount of silicon element, and iii) forming the at least one silicide coating layer. | 10-28-2010 |
20120267441 | METHODS AND SYSTEM FOR COOLING A REACTION EFFLUENT GAS - In one embodiment, a method for cooling a reaction effluent gas includes feeding a sufficient amount of a suitable silicon source cooling gas into a stream of the reaction effluent gas, wherein the reaction effluent gas is produced by a thermal decomposition of at least one silicon source gas in a reactor, and wherein sufficient amount of the suitable silicon source cooling gas is defined based a concentration of the at least one chemical species in the reaction effluent gas; cooling the reaction effluent gas to a sufficient temperature so that: the cooled reaction effluent gas is capable of being handled by a material that is not suitable for handling the reaction effluent gas. | 10-25-2012 |
Patent application number | Description | Published |
20080235705 | Methods and Apparatus for Global Systems Management - Techniques for globally managing systems are provided. One or more measurable effects of at least one hypothetical action to achieve a management goal are determined at a first system manager. The one or more measurable effects are sent from the first system manager to a second system manager. At the second system manager, one or more procedural actions to achieve the management goal are determined in response to the one or more received measurable effects. The one or more procedural actions are executed to achieve the management goal. | 09-25-2008 |
20090276787 | PERFORMING DYNAMIC SIMULATIONS WITHIN VIRTUALIZED ENVIRONMENT - A method and apparatus for and article of manufacture for simulating workloads experienced by multiple partitions in a virtualized system are provided. A master workload driver initiates, coordinates and regulates one or more workload drivers that execute one or more workload simulation tasks in a logical partition. Further, each workload driver may be configured to report a measure of performance regarding the workload to the master control driver where results of many workload drivers may be correlated and analyzed. A configuration file specifies the characteristics of each simulation. Further, the rate and nature of workloads may be adjusted dynamically during a given simulation to model the performance under different real-world scenarios of different computational loads that may be experienced by the virtualized system. | 11-05-2009 |
20100094861 | SYSTEM AND METHOD FOR APPLICATION SESSION TRACKING - A system and method for application session tracking includes activating an application component for execution using an application session tracking facility (ASTF) and intercepting resource requests by the ASTF acting on behalf of this application. Resources are managed by allocating or releasing resources in accordance with resource usage profiles determined by system or application administrators of an application. The ASTF approach allows for controlling the usage of (potentially) distributed resources such as temporary space, database assets such as materialized views, directory services, shared memory segments among others during runtime and their return to their respective free pools and any necessary subsequent cleanup tasks upon a session termination. | 04-15-2010 |
20110106968 | Techniques For Improved Clock Offset Measuring - In an exemplary aspect, method, apparatus, and program products are disclosed suitable for clock offset determination. One method includes performing a number of exchanges of at least single bytes with another network node, where values of the single bytes are different for the exchanges. The method also includes capturing and storing timestamps for each of the number of exchanges performed on the network node. A second method includes capturing and saving arrival timestamps for each of a number of timing messages in a set of timing messages received from another network node. This second method also includes sending the timestamps to at least the another node in response to completion of the set of timing messages. | 05-05-2011 |