Patent application number | Description | Published |
20080306006 | MicroRna-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Solid Cancers - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provide methods of identifying inhibitors of tumorigenesis. | 12-11-2008 |
20080306018 | Micro-Rna Expression Abnormalities of Pancreatic, Endocrine and Acinar Tumors - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of pancreatic cancer. The invention also provides methods of identifying anti-pancreatic cancer agent. | 12-11-2008 |
20090209450 | MicroRNA Fingerprints During Human Megakaryocytopoiesis - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of cancer and myeloproliferative disorders. The invention also provides methods of identifying anti-cancer agents. | 08-20-2009 |
20100197774 | MicroRNA EXPRESSION ABNORMALITIES IN PANCREATIC ENDOCRINE AND ACINAR TUMORS - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of pancreatic cancer. The invention also provides methods of identifying anti-pancreatic cancer agent. | 08-05-2010 |
20110052502 | MicroRNA Signatures Associated with Human Chronic Lymphocytic Leukemia (CCL) and Uses Thereof - Methods and compositions for the diagnosis, prognosis and/or treatment of leukemia associated diseases are disclosed. | 03-03-2011 |
20110287970 | MICRORNA FINGERPRINTS DURING HUMAN MEGAKARYOCYTOPOIESIS - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of cancer and myeloproliferative disorders. The invention also provides methods of identifying anti-cancer agents. | 11-24-2011 |
20120214688 | Methods for Diagnosing Breast, Colon, Lung, Pancreatic and Prostate Cancer Using miR-21 and miR-17-5p - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214689 | Methods for Diagnosing Breast and Lung Cancer Using miR-210 and miR-213 - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214690 | Methods for Diagnosing Colon, Stomach, Prostate and Pancreas Cancer Using miR-223 - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214691 | Methods for Diagnosing Breast Cancer Using miR-21, miR-125-1, miR-125b-2 and miR-145 - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214692 | Methods for Diagnosing Pancreatic Cancer Using miR-103-1, miR-103-2, miR-24-2 and miR-107 - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214693 | Methods for Diagnosing Breast Cancer Using MicroRNAs - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214694 | Methods for Diagnosing Colon Cancer Using MicroRNAs - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214695 | Methods for Diagnosing Lung Cancer Using MicroRNAs - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214696 | Methods for Diagnosing Pancreatic Cancer Using MicroRNAs - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214697 | Methods for Diagnosing Prostate Cancer Using MicroRNAs - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214698 | Methods for Diagnosing Stomach Cancer Using MicroRNAs - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214699 | Methods for Diagnosing Breast Cancer Using MicroRNA Signatures - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214700 | Methods for Diagnosing Colon Cancer Using MicroRNA Signatures - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214701 | Methods for Diagnosing Lung Cancer Using MicroRNA Signatures - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214702 | Methods for Diagnosing Prostate Cancer Using MicroRNA Signatures - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120214703 | Methods for Diagnosing Stomach Cancer Using MicroRNA Signatures - The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. | 08-23-2012 |
20120283310 | MicroRNA Signatures Associated with Human Chronic Lymphocytic Leukemia (CLL) and Uses Thereof - Methods and compositions for the diagnosis, prognosis and/or treatment of leukemia associated diseases are disclosed. | 11-08-2012 |
20120322859 | MicroRNA Fingerprints During Human Megakaryocytopoiesis - Described herein is a method of decreasing expression of HOXA1 in a subject having a cancer and/or myeloproliferative disorder associated with overexpression of a HOXA1 gene product where an effective amount of at least one miR-10a gene product or an isolated variant or biologically-active fragment thereof is administered to the subject sufficient to decrease expression of the HOXA1 gene product in the subject. | 12-20-2012 |
20120329053 | MicroRNA Fingerprints During Human Megakaryocytopoiesis - Described herein is a method of decreasing expression of HOXA1 in a subject having a cancer and/or myeloproliferative disorder associated with overexpression of a HOXA1 gene product where an effective amount of at least one miR-10a gene product or an isolated variant or biologically-active fragment thereof is administered to the subject sufficient to decrease expression of the HOXA1 gene product in the subject. | 12-27-2012 |
20120329859 | MicroRNA Fingerprints During Human Megakaryocytopoiesis - Described herein is a method of decreasing expression of MAFB in a subject having a cancer and/or myeloproliferative disorder associated with overexpression of a MAFB gene product where an effective amount of at least one miR-130a gene product or an isolated variant or biologically-active fragment thereof is administered to the subject sufficient to decrease expression of the MAFB gene product in the subject. | 12-27-2012 |
20130137596 | MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of pancreatic cancer. The invention also provides methods of identifying anti-pancreatic cancer agent. | 05-30-2013 |
20130267580 | Compositions and Methods for the Diagnosis and Therapy of BCL2-Associated Cancers - Provided are methods and compositions for the treatment of cancers associated with overexpression of a BCL2 gene and/or gene product in a subject, and methods and compositions for the improvement of anti-cancer therapy, such as chemotherapy and radiation therapy. Also provided are methods for determining the efficacy of a cancer therapy in a subject, methods for diagnosing cancer, methods for assessing patient prognosis, and methods for inducing apoptosis of a cell. | 10-10-2013 |
20130273151 | MicroRNA Fingerprints During Human Megakaryocytopoiesis - Described herein is a pharmaceutical composition for treating a subject having a cancer and/or myeloproliferative disorder associated with overexpression of a HOXA1 gene product where an effective amount of at least one miR-10a gene product or an isolated variant or biologically-active fragment thereof is administered to the subject sufficient to decrease expression of the HOXA1 gene product in the subject. | 10-17-2013 |
20130274140 | MicroRNA Fingerprints During Human Megakaryocytopoiesis - Described herein are methods of diagnosing a cancer and/or myeloproliferative disorder using microRNAs. Also described are compositions and methods related to cancers and myeloproliferative disorders. | 10-17-2013 |
20130324589 | Methods for Diagnosing Pancreatic Cancer Using MicroRNAs - Described herein are methods for diagnosing pancreatic cancer using microRNAs. Also described are methods and compositions for the diagnosis and treatment of solid cancers. Methods of identifying inhibitors of tumorigenesis are also provided. | 12-05-2013 |
20130331439 | Methods for Diagnosing Stomach Cancer Using MicroRNAs - Described herein are methods for diagnosing stomach cancer using microRNAs. Also described are methods and compositions for the diagnosis and treatment of solid cancers. Methods of identifying inhibitors of tumorigenesis are also provided. | 12-12-2013 |
20140018411 | Methods for Diagnosing Prostate Cancer using MicroRNAs - Described herein are methods for diagnosing prostate cancer using microRNAs. Also described are methods and compositions for the diagnosis and treatment of solid cancers. Methods of identifying inhibitors of tumorigenesis are also provided. | 01-16-2014 |
20140018412 | Methods for Diagnosing Lung Cancer using MicroRNAs - Described herein are methods for diagnosing lung cancer using microRNAs. Also described are methods and compositions for the diagnosis and treatment of solid cancers. Methods of identifying inhibitors of tumorigenesis are also provided. | 01-16-2014 |
20140045709 | MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of pancreatic cancer. The invention also provides methods of identifying anti-pancreatic cancer agent. | 02-13-2014 |
20140100133 | Methods for Diagnosing Breast Cancer Using MicroRNAs - Described herein are methods for diagnosing breast cancer using microRNAs. Also described are methods and compositions for the diagnosis and treatment of solid cancers. Methods of identifying inhibitors of tumorigenesis are also provided. | 04-10-2014 |
20140147495 | MicroRNA-Based Methods and Compositions For the Diagnosis, Prognosis and Treatment of Breast Cancer - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of breast cancer. The invention also provides methods of identifying anti-breast cancer agents. | 05-29-2014 |
20140161869 | MicroRNA Fingerprints During Human Megakaryocytopoiesis - Described herein are compositions and methods of decreasing expression of MAFB in a subject having a cancer and/or myeloproliferative disorder associated with overexpression of a MAFB gene product where an effective amount of at least one miR-130a gene product or an isolated variant or biologically-active fragment thereof is administered to the subject sufficient to decrease expression of the MAFB gene product in the subject. | 06-12-2014 |
20140256040 | DIAGNOSIS AND TREATMENT OF CANCERS WITH MICRORNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES - MicroRNA genes are highly associated with chromosomal features involved in the etiology of different cancers. The perturbations in the genomic structure or chromosomal architecture of a cell caused by these cancer-associated chromosomal features can affect the expression of the miR gene(s) located in close proximity to that chromosomal feature. Evaluation of miR gene expression can therefore be used to indicate the presence of a cancer-causing chromosomal lesion in a subject. As the change in miR gene expression level caused by a cancer-associated chromosomal feature may also contribute to cancerigenesis, a given cancer can be treated by restoring the level of miR gene expression to normal. microRNA expression profiling can be used to diagnose cancer and predict whether a particular cancer is associated with an adverse prognosis. The identification of specific mutations associated with genomic regions that harbor miR genes in CLL patients provides a means for diagnosing CLL and possibly other cancers. | 09-11-2014 |
20140335161 | Compositions and Methods for the Diagnosis and Therapy of BCL2-Associated Cancers - Provided are methods and compositions for the treatment of cancers associated with overexpression of a BCL2 gene and/or gene product in a subject, and methods and compositions for the improvement of anti-cancer therapy, such as chemotherapy and radiation therapy. Also provided are methods for determining the efficacy of a cancer therapy in a subject, methods for diagnosing cancer, methods for assessing patient prognosis, and methods for inducing apoptosis of a cell. | 11-13-2014 |