Patent application number | Description | Published |
20080214913 | Surface-Enhanced Spectroscopy with Implanted Biosensors - The present invention provides a spectroscopic apparatus, a method and a computer program product for determining the concentration of an analyte of a fluid that flows through a capillary vessel of a biological sample. The spectroscopic apparatus makes use of an imaging system for determining the position of at least one biosensing substrate that has been implanted into the biological sample in the proximity of the capillary vessel but outside the capillary vessel. The biosensing substrate is capable of inducing surface-enhanced spectroscopic effects and is preferably adapted to reversibly and selectively bind a certain analyte or molecule of the fluid, to which the vessel wall of the capillary vessel is at least semi-permeable. By performing a spectroscopic analysis not directly inside the capillary vessel but in close proximity to the capillary vessel, the signal-to-noise ratio of the spectroscopic signals obtained can be appreciably enhanced while disadvantageous scattering and interference effects can be minimized. | 09-04-2008 |
20080221519 | System for Guiding a Probe Over the Surface of the Skin of a Patient or an Animal - The invention relates to a system for guiding a probe over the surface of the skin of a patient. Performing measurements with ultrasound techniques for small structures such as blood vessels need well-defined spatial relationship between the measuring probe and the tissue which has to be examined. The invention seeks to ensure a movement of the measuring probe in a controlled and precise way over the skin. Therefore, a system | 09-11-2008 |
20080275396 | Cannula Inserting System - The present invention provides a highly automated puncture system for inserting a cannula or a needle into a blood vessel of a person or an animal. The puncture system has an acquisition module that allows for determining at least a location of a blood vessel underneath of the surface of a skin and is further enabled to determine an optimal puncture location that is well suitable for inserting a cannula into the blood vessel. Further, the puncture system has an actuator for moving and aligning the cannula to a determined position. The system is further adapted to autonomously insert the cannula into the blood vessel for multiple purposes, such as blood withdrawal, venous medication and infusions. | 11-06-2008 |
20080312532 | System and Method for Interacting With a Cell or Tissue in a Body | 12-18-2008 |
20090118670 | Cannula inserting system - The invention relates to a highly automated puncture system for inserting a cannula or a needle into a blood vessel of a person or an animal. The puncture system has an acquisition module that allows for determining at least a location of a blood vessel underneath of the surface of a skin and is further enabled to determine an optimal puncture location that is potentially suitable for inserting a cannula into the blood vessel. Further, the puncture system has tissue analysis means to analyse the skin surface in the proximity of the puncture location to check whether the skin is suitable for punctuation. This prevents puncturing the skin at locations where scars, wound and the like can be found. | 05-07-2009 |
20090131772 | MEDICAL DEVICE - A medical device ( | 05-21-2009 |
20090143774 | APPARATUS FOR DEPTH-RESOLVED MEASUREMENTS OF PROPERTIES OF TISSUE - The invention relates to an apparatus ( | 06-04-2009 |
20090170070 | INCREASED SPECIFICITY OF ANALYTE DETECTION BY MEASUREMENT OF BOUND AND UNBOUND LABELS - The present invention describes the provision of an internal control in analytical techniques involving labeling of analytes, such as SERRS, for detection of an analyte, particularly a biomolecule in a sample, with improved accuracy. | 07-02-2009 |
20090198113 | DEDICATED SPECTRAL ILLUMINATION SPECTROSCOPY - Apparatus and method for an analyte determination in blood, relying on spectroscopic techniques, in which sample is illuminated with light having dedicated spectral characteristics. The first light source ( | 08-06-2009 |
20090273778 | SURFACE ENHANCED RESONANT RAMAN SPECTROSCOPY - A method of performing surface-enhanced resonant Raman spectroscopy (SERRS) in respect of a sample ( | 11-05-2009 |
20090275823 | CANNULA INSERTING SYSTEM - The present invention provides a highly automated puncture system for inserting a cannula or a needle into a blood vessel of a person or an animal. The puncture system has an acquisition module that allows for determining at least one location of a blood vessel underneath the surface of a skin and that is further enabled to determine an optimal puncture location that is well suitable for inserting a cannula into the blood vessel. Further, the puncture system has an actuator for moving and aligning the cannula to a determined position. The system is further adapted to autonomously insert the cannula into the blood vessel for multiple purposes, such as blood withdrawal, venous medication and infusions. | 11-05-2009 |
20090318908 | SKIN MONITORING DEVICE, METHOD OF MONITORING THE SKIN, MONITORING DEVICE, METHOD OF IRRADIATING THE SKIN, AND USE OF AN OLED - Skin monitoring device for application near the skin, comprising a processing circuit connecting means and at least one photosensor configured to detect at least one approximate wavelength of light reflected and/or emitted by the skin, wherein a signal receiving circuit is provided for receiving signals from the at least one photosensor. | 12-24-2009 |
20100002223 | EXTERNAL MICROCONTROLLER FOR LED LIGHTING FIXTURE, LED LIGHTING FIXTURE WITH INTERNAL CONTROLLER, AND LED LIGHTING SYSTEM - A detector ( | 01-07-2010 |
20100087739 | APPARATUS FOR OPTICAL BODY ANALYSIS - An apparatus for optical body analysis is built with an illumination and detection head, and an optical coupler. The illumination and detection head comprises a light source for illuminating a body portion to analyze through the optical coupler and a detector for receiving light diffusely reflected by the body portion. The optical coupler is mechanically decoupled from the illumination and detection head and is adapted to be in contact with an outer surface of the body portion while the contact between the optical coupler and the body portion minimally affects physical properties of the body portion. The apparatus may further comprise a position unit adapted to adjust the position of the illumination and detection head relative to the optical coupler so that the detector receives through the optical coupler light generated by the light source and diffusely reflected by the body portion. | 04-08-2010 |
20100094385 | TEMPERATURE CONTROL OF PATIENTS DURING SURGERY - An infrared radiant heating system for raising or maintaining a uniform core temperature of the body of a patient during surgery, substantially without affecting the temperature of the area surrounding the patient's body, comprising: infrared radiant heating means which in use is located in an unobtrusive position near the patient to provide radiant heat to the entire body or one or more parts of the body of the patient; and control means in communication with the heating means for controlling the intensity level and distribution of intensity of the radiant heat on the patient's body such that in use the skin temperature of the patient's body is raised or maintained within a predetermined range resulting in the uniform core body temperature, substantially without affecting the temperature of the area surrounding the patient's body. | 04-15-2010 |
20100105020 | QUANTITATIVE MEASUREMENT OF GLYCATED HEMOGLOBIN - The invention relates to a method for quantitative measurement of glycated hemoglobin (HbAIc) in a blood sample containing hemoglobin molecules. In this method, the hemoglobin molecules are extracted from the blood sample, adsorbed onto a roughened metal surface and subjected to a Surface Enhanced Raman Scattering (SERS) measurement. The invention provides a universal method for the measurement of the HbAIc concentration in blood. | 04-29-2010 |
20130026367 | DETERMINATION OF A LIPID WATER RATIO - The present invention relates to an apparatus, a method and a computer program for determining a lipid-water ratio and a scattering parameter of a sample. In particular, the invention relates to an apparatus comprising a light source and a detector arranged to measure an optical parameter at various wavelengths, where the wavelengths are selected so that at two of the wavelengths the absorption coefficients for both water and lipids are substantially identical. This enables determination of a scattering parameter. A further measurement at a third wavelength enables determination of a water-lipid ratio. According to a specific embodiment, the light source and the detector are arranged in relation to an interventional device, so as to be able to examine a tissue in terms of lipid-water ratio and scattering during an intervention. | 01-31-2013 |
20130050683 | EXTENDING IMAGE INFORMATION - The present invention relates to a system for extending microscopy information, where the microscopy information is image information from a first region ( | 02-28-2013 |
20130217989 | SPLITTABLE NEEDLE WITH FIBER PROBE - A needle comprises an elongated first shaft element with a C-shaped cross section and an elongated second shaft element with a C-shaped cross section. The first shaft element and the second shaft element are adapted to be detachably connected to each other. This is achieved by an overlap of respective end sections of the first and second shaft elements. Within the channel formed by the shaft elements, an optical probe may be accommodated from which the shaft elements may be removed by separating the two shaft elements from each other. | 08-22-2013 |
20140046197 | CLASSIFICATION OF TUMOR TISSUE WITH A PERSONALIZED THRESHOLD - The present invention deals with discrimination of malignant tissue from normal and benign tissue in a single patient on the basis of optical spectroscopic measurements. Starting from spectroscopic measurements in normal tissue, reference values are obtained for the normal class. With spectroscopic measurements in other tissues data points can be assigned to new class(es) when the spectral characteristics fall outside a threshold defining the reference class. Thresholds between different classes can also be defined. Finding (the transition to) malignant tissue is based on comparing the spectroscopic values to the classification threshold discriminating normal and benign versus malignant tissue. Thus, the basis of normal spectroscopic measurements is tuned to the individual patient characteristic. Discriminating the normal plus benign and malignant from that reference is more efficient compared to the reference of the all patient database. | 02-13-2014 |
20140121538 | NEEDLE WITH AN OPTICAL FIBER INTEGRATED IN AN ELONGATED INSERT - A needle is proposed including a cannula or hollow shaft with a multilumen insert inside. The insert comprises at least two lumen. Both the insert as well as the cannula have bevelled ends. In the insert substantially straight cleaved fibers are present that may be connected at the proximal end to a console. At least one of the distal fiber ends in the insert may protrude more than half the fiber diameter out of the insert. Furthermore, the bevel angle of the insert is different from the bevel angle of the cannula such that combination cannula and insert is such that the fiber ends do not protrude the bevel surface of the cannula. | 05-01-2014 |
20140142563 | ENERGY APPLICATION PLANNING APPARATUS - The invention relates to an energy application planning apparatus for planning an application of energy to an object ( | 05-22-2014 |
20140200459 | APPARATUS FOR OPTICAL ANALYSIS OF AN ASSOCIATED TISSUE - The present invention relates to an apparatus | 07-17-2014 |
20140236024 | MEDICAL PROBE WITH MULTI-FIBER LUMEN - The present invention relates to a medical probe which consists of a cannula with a multilumen stylet inside. The multilumen contains at least two lumen. Both the multilumen as well as the cannula may have beveled ends. In the lumen straight optical fibers (i.e.no angle end face) are present that can be connected at the proximal end to a console. The cannula, multilumen, fiber system forming the medical probe comprises at least in one of the lumen of the multilumen more than one optical fiber. Preferably the source and detector fibers for the fluorescence detection are contained in one single lumen of the multilumen. | 08-21-2014 |
20140316280 | DETECTION APPARATUS FOR DETERMINING A STATE OF TISSUE - The invention relates to a detection apparatus ( | 10-23-2014 |
20140363063 | IMAGING APPARATUS - The invention relates to an imaging apparatus ( | 12-11-2014 |
20140378797 | APPARATUS FOR OPTICAL ANALYSIS OF AN ASSOCIATED TISSUE - The present invention relates to an apparatus | 12-25-2014 |
20150057530 | MEDICAL NEEDLE - The present invention relates to a medical needle which comprises a needle ( | 02-26-2015 |