Gubler, US
Brad Gubler, Atlanta, GA US
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20160071056 | PROGRAMMATICALLY EXECUTING TIME COMPRESSED DELIVERY - Computer program products, methods, systems, apparatus, and computing entities are provided for determining whether available and executing time compressed/sensitive delivery. In one exemplary embodiment, a method may comprise receiving an electronic notification comprising pick-up locations, delivery locations and a time window, determining whether the items can be picked up at the pick-up locations and delivered to one of the delivery locations within the time window based on available delivery vehicles, available delivery drivers, planned routes, physical vehicle capacity, planned sort capabilities, available meet points, and available pick-up times, and in an instance in which it is determined that the items can be picked up at one of the pick-up locations and delivered to one of the delivery locations within the time window, providing an affirmative response. | 03-10-2016 |
Duane J. Gubler, St. George, UT US
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20140141040 | AVIRULENT, IMMUNOGENIC FLAVIVIRUS CHIMERAS - Chimeric flaviviruses that are avirulent and immunogenic are provided. The chimeric viruses are constructed to contain amino acid mutations in the nonstructural viral proteins of a flavivirus. Chimeric viruses containing the attenuation-mutated nonstructural genes of the virus are used as a backbone into which the structural genes of a second flavivirus strain are inserted. These chimeric viruses elicit pronounced immunogenicity yet lack the accompanying clinical symptoms of viral disease. The attenuated chimeric viruses are effective as immunogens or vaccines and may be combined in a pharmaceutical composition to confer simultaneous immunity against several strains of pathogenic flaviviruses. | 05-22-2014 |
Duane J. Gubler, Fort Collins, CO US
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20090010961 | Avirulent, immunogenic flavivirus chimeras - Chimeric flaviviruses that are avirulent and immunogenic are provided. The chimeric viruses are constructed to contain amino acid mutations in the nonstructural proteins of a flavivirus. Chimeric viruses containing the attenuation-mutated nonstructural genes of the virus are used as a backbone into which the structural protein genes of a second | 01-08-2009 |
20100255030 | AVIRULENT, IMMUNOGENIC FLAVIVIRUS CHIMERAS - Chimeric flaviviruses that are avirulent and immunogenic are provided. The chimeric viruses are constructed to contain amino acid mutations in the nonstructural viral proteins of a flavivirus. Chimeric viruses containing the attenuation-mutated nonstructural genes of the virus are used as a backbone into which the structural genes of a second flavivirus strain are inserted. These chimeric viruses elicit pronounced immunogenicity yet lack the accompanying clinical symptoms of viral disease. The attenuated chimeric viruses are effective as immunogens or vaccines and may be combined in a pharmaceutical composition to confer simultaneous immunity against several strains of pathogenic flaviviruses. | 10-07-2010 |
20120014981 | AVIRULENT, IMMUNOGENIC FLAVIVIRUS CHIMERAS - Chimeric flaviviruses that are avirulent and immunogenic are provided. The chimeric viruses are constructed to contain amino acid mutations in the nonstructural viral proteins of a flavivirus. Chimeric viruses containing the attenuation-mutated nonstructural genes of the virus are used as a backbone into which the structural genes of a second flavivirus strain are inserted. These chimeric viruses elicit pronounced immunogenicity yet lack the accompanying clinical symptoms of viral disease. The attenuated chimeric viruses are effective as immunogens or vaccines and may be combined in a pharmaceutical composition to confer simultaneous immunity against several strains of pathogenic flaviviruses. | 01-19-2012 |
Jeffery V. Gubler, Springville, UT US
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20110048266 | Crafting Apparatus Including a Workpiece Feed Path Bypass Assembly and Workpiece Feed Path Analyzer - A method of operating a crafting apparatus. The method includes moving a workpiece along a first feed path for printing on the workpiece with a printer and moving the workpiece along a second feed path for cutting the workpiece with a cutter. The first feed path bypasses a workpiece mover of the cutter. | 03-03-2011 |
20110052301 | (Moab Omnibus-Apparatus) Crafting Apparatus Including a Workpiece Feed Path Bypass Assembly and Workpiece Feed Path Analyzer - A crafting apparatus that includes a body defining at least one passageway for receiving a workpiece, a cutter disposed along the at least one passageway, a printer disposed along the at least one passageway and spaced from the cutter, and a feed path bypass assembly disposed along the at least one passageway between the cutter and the printer. The feed path bypass assembly alters a feed path of the workpiece through the at least one passageway. | 03-03-2011 |
20110280999 | Foodstuff Crafting Apparatus, Components, Assembly, and Method for Utilizing the Same - A crafting apparatus that performs work on a workpiece is disclosed. The workpiece includes, for example, an edible foodstuff material. In an embodiment, the edible foodstuff material includes nutritional value and is consumable by, for example, human beings, animals or the like. | 11-17-2011 |
20140169855 | Crafting Apparatus Including a Workpiece Feed Path Bypass Assembly and Workpiece Feed Path Analyzer - A method of operating a crafting apparatus. The method includes moving a workpiece along a first feed path for printing on the workpiece with a printer and moving the workpiece along a second feed path for cutting the workpiece with a cutter. The first feed path bypasses a workpiece mover of the cutter. | 06-19-2014 |
20140170593 | PATCH FOR NON-INVASIVE PAIN RELIEF - Adhesive patches for non-invasive pain relief comprising a molded backing layer including first and second well portions. An adhesive composition (e.g., chitosan derived) is disposed within the first well composition, and a skin penetrating anesthetic composition is disposed within the second well portion. The first well portion surrounds the perimeter of the second well portion, creating a barrier to prevent or minimize migration of the anesthetic composition outside the perimeter of the second well portion, targeting delivery to the desired site. The skin penetrating anesthetic composition includes a skin penetrating carrier (e.g., DMSO with small fractions of water and ethanol), a primary adhesive component (e.g., hydroxypropyl cellulose) to render the anesthetic composition sticky to the person's tissue, and at least one anesthetic component (e.g., -caine based components). Where two anesthetic components are included, one may act more rapidly to anesthetize pain than the first anesthetic component. | 06-19-2014 |
20160026168 | Electronic Cutting Machine - An electronic cutting machine includes at least one housing to which a drive roller is coupled for moving a sheet to be cut in a first direction and a cutter assembly coupled to the housing and moveable in a second direction that is perpendicular to the first direction. | 01-28-2016 |
Jeffrey V. Gubler, Springville, UT US
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20100064911 | EMBOSSING DEVICE AND METHODS FOR USING AND MANUFACTURING THE SAME - An assembly is disclosed. The assembly includes an embossing device including a blank portion workpiece including a plurality of layers, wherein the blank portion workpiece is separated to include a first blank portion and a second blank portion, wherein each of the first and second blank portions include portions of at least two layers of the plurality of layers; and a blank portion retainer including a first flap and a second flap, wherein the first flap and the second flap are connected by a member consisting of a hinge, wherein the hinge and the first flap and the second flap define a folder, wherein each of the first and second flaps define an inner surface and an outer surface, wherein the first blank portion is attached to the inner surface of the first flap, wherein the second blank portion is attached to the inner surface of the second flap | 03-18-2010 |
20110073519 | Decorative Object Arrangement Device and Method for Utilizing the Same - An arrangement device is disclosed. The arrangement device includes a tray portion having a body that forms a plurality of passages. The arrangement device also includes a plurality of pattern adjustment plungers movably-secured to the tray portion within the plurality of passages. | 03-31-2011 |
Justin L. Gubler, Scottsdale, AZ US
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20140026188 | SYSTEMS, METHODS, AND DEVICES FOR RESTRICTING USE OF ELECTRONIC DEVICES BASED ON PROXIMITY TO WIRELESS DEVICES - Systems, kits, methods, and software are disclosed for securing access to an electronic device such as a smartphone, tablet, e-reader, portable media player, and the like. The electronic device includes a security application and a network interface. The network interface is configured to be paired with or otherwise communicatively connect to a separate security device. If the application determines that communication is possible or occurring, access to the electronic device may be enabled. If the application determines that communication is not possible, some, all, or substantially all features of the electronic device may be disabled. The disabled device may be re-enabled manually using an override code, or automatically be re-initiating communication with the security device. | 01-23-2014 |
Kenneth Bradley Gubler, Marietta, GA US
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20150142691 | CONCEPTS FOR ELECTRONIC DOOR HANGERS - Computer program products, methods, systems, apparatus, and computing entities are provided. In one embodiment, a connection between an electronic door hanger and a customer computing entity can be established at a customer's location. With a connection established, information about an attempted (e.g., successful/unsuccessful) pick-up or delivery can be automatically provided to the customer computing entity. | 05-21-2015 |
20150142692 | CONCEPTS FOR ELECTRONIC DOOR HANGERS - Computer program products, methods, systems, apparatus, and computing entities are provided. In one embodiment, a connection between an electronic door hanger and a customer computing entity can be established at a customer's location. With a connection established, information about an attempted (e.g., successful/unsuccessful) pick-up or delivery can be automatically provided to the customer computing entity. | 05-21-2015 |
20150154559 | SYSTEMS AND METHODS FOR DELIVERING AN ITEM TO A DYNAMIC LOCATION - Various embodiments of the present invention involve systems, methods, and computer program products utilized in facilitating alternative delivery options for customers. In certain embodiments, a consignee may meet a driver and receive an item at a location different from the delivery address associated with the item. The receipt of the item may be prior to the driver attempting to deliver the item to the designated shipping location or after an unsuccessful delivery attempt. The carrier, the driver, the carrier system, the mobile station, and/or the sensors located on the item may communicate with the consignee to arrange a mutually acceptable time and location to accomplish the delivery. In certain embodiments, the consignee may be responsible for arriving at a dynamic delivery location to retrieve the item while the driver is at the location performing other tasks. | 06-04-2015 |
Ulrich A. Gubler, Glen Ridge, NJ US
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20090298756 | FUNCTIONS AND USES OF GPR39 GENE IN MAMMALIAN CENTRAL NERVOUS SYSTEM - The present invention provides mammalian GPR39 gene, its coded products, and the uses in regulating appetite and pain sensitivity. A pharmaceutical composition and a health product comprising GPR39 protein are also provided. The health product and the pharmaceutical composition for suppressing appetite or decreasing pain sensitivity comprise a safe and efficient amount of antagonists of mammalian GPR39 protein (for example, 0.01-99%) and a bromatologically or pharmaceutically acceptable carrier in a suitable amount (for example 1-99.99 wt %). | 12-03-2009 |
Ulrich Andreas Gubler, Glen Ridge, NJ US
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20100261191 | STABLE CELL LINES EXPRESSING HERG - A stable eukaryotic cell line that expresses hERG and exhibits a stable current under electrophysiological test conditions is provided. | 10-14-2010 |
Walter D. Gubler, Davis, CA US
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20120264353 | METHOD FOR TRAINING HONEYBEES TO RESPOND TO OLFACTORY STIMULI AND ENHANCEMENT OF MEMORY RETENTION THEREIN - A specialized conditioning protocol for honeybees that is designed for use within a complex agricultural ecosystem. This method ensures that the conditioned bees will be less likely to exhibit a conditioned response to uninfected plants, a false positive response that would render such a biological sensor unreliable for agricultural decision support. Also described is a superboosting training regime that allows training without the aid of expensive equipment and protocols for training in out in the field. Also described is a memory enhancing cocktail that aids in long term memory retention of a vapor signature. This allows the bees to be used in the field for longer durations and with fewer bees trained overall. | 10-18-2012 |