Patent application number | Description | Published |
20080299541 | METHOD AND APPARATUS FOR MEASURING ENZYMATIC ACTIVITY BY USE OF LASER - A method of measuring an enzymatic activity, includes measuring the quantity of a substrate metabolite produced upon metabolism of a substrate by an enzyme, through detecting a radiant wave generated from a multiple photon excitation process of the substrate or the substrate metabolite. | 12-04-2008 |
20090275743 | METHOD OF PREPARING CARRIER TO SEPARATE NUCLEIC ACIDS, CARRIER AND MICRO CHANNEL TO SEPARATE NUCLEIC ACIDS, AND METHOD AND APPARATUS FOR SEPARATING NUCLEIC ACIDS - The present invention provides a method for producing a carrier for nucleic acid separation, the method including a step of: immobilizing capturing chains onto a porous carrier having cation-exchangeable groups thereon by ion exchange bonding, the capturing chains having a base sequence complementary to target nucleic acid chains and being modified with functional groups having positive charges. | 11-05-2009 |
20090324498 | METHOD OF MEASURING QUANTITY OF IN-VIVO SUBSTANCE BY USE OF COHERENT ANTI-STOKES RAMAN SCATTERED LIGHT - A method of measuring the quantity of an in-vivo substance includes the steps of: irradiating an in-vivo substance with two near infrared femtosecond laser beams of different frequencies; detecting coherent anti-Stokes Raman scattered light emitted from the in-vivo substance due to coincidence of the frequency difference between the two near infrared femtosecond laser beams with a natural frequency of the in-vivo substance; and determining the quantity of the in-vivo substance, based on a peak intensity of a Raman scattering spectrum obtained. | 12-31-2009 |
20110312036 | MICROCHIP FOR ISOTHERMAL NUCLEIC-ACID AMPLIFICATION REACTION, METHOD FOR PRODUCING THE SAME, AND ISOTHERMAL NUCLEIC-ACID AMPLIFICATION METHOD - A microchip for an isothermal nucleic-acid amplification reaction in which at least one of substances necessary for an isothermal amplification reaction of a nucleic acid is present in a reaction region functioning as a reaction field of the reaction, the at least one of the substances being covered with a thin film that melts at a temperature higher than room temperature and lower than a reaction temperature of the reaction. | 12-22-2011 |
20120010097 | MICROCHANNEL, AND NUCLEIC ACID HYBRIDIZATION MICROCHIP, COLUMN, SYSTEM AND METHOD - A microchannel capable of passing therethrough a solution with target nucleic acid strands contained therein includes: an agarose gel carrier having light transmission properties, supporting capture strands having a base sequence complementary to that of the target nucleic acid strands and immobilized on the agarose gel carrier, and packed in the microchannel; and a filter arranged in the microchannel on a downstream side as viewed in a passing direction of the solution and retaining the agarose gel carrier. | 01-12-2012 |
20120121484 | MICROCHIP - Disclosed herein is a microchip that allows a sample to be introduced into a region easily and accurately, and which makes it possible to obtain high analysis accuracy. The microchip includes an airtight region into which a solution is externally introduced; and positioning means for positioning a channel for injecting the solution into the region by penetrating a substrate layer forming the region with respect to a puncture part of the region. | 05-17-2012 |
20120149005 | REACTION TREATMENT DEVICE AND REACTION TREATMENT METHOD - Disclosed herein is a reaction treatment device including a temperature control section which includes a first temperature control section disposed at an outer peripheral edge part of a group of reaction regions and a planar second temperature control section, wherein the first temperature control section and the second temperature control section are disposed opposite to each other, with the reaction region group therebetween. | 06-14-2012 |
20120195796 | SAMPLE LIQUID SUPPLY DEVICE, SAMPLE LIQUID SUPPLY DEVICE SET, AND MICROCHIP SET - A sample liquid supply device includes a container tip into which the sample liquid is introduced, a hollow needle provided at one end of the container tip such that a hollow part thereof communicates with inside of the container tip, and a sealing member that covers an opening from which the sample liquid is introduced, wherein the sealing member has a puncture-sealing property achieved by elastic deformation. | 08-02-2012 |
20120295257 | METHOD, MICROCHIP AND MIXED REAGENT FOR ANALYSIS OF NUCLEIC ACID BASE SEQUENCE - A technology is provided for achieving high efficiency of nucleic acid amplification reaction and high precision of melting curve analysis when performing melting curve analysis in a nucleic acid amplification process of obtaining an amplification product in which the target nucleic acids are continuously arranged via a loop. A method for analysis of nucleic acid base sequence is provided, and includes: performing amplification reaction of target nucleic acid which is targeted for amplification, in presence of a probe nucleic acid that is capable of hybridizing with the target nucleic acid, to obtain an amplification product in which the target nucleic acids are continuously arranged via a loop site and employing as the probe nucleic acid, a probe nucleic acid having a melting temperature which is lower than the reaction temperature of the amplification reaction; and performing melting curve analysis of the amplification product and the probe nucleic acid. | 11-22-2012 |
20120301372 | MICROCHIP AND METHOD OF PRODUCING MICROCHIP - A microchip is provided. The microchip (A) includes a substrate structure including a fluid channel ( | 11-29-2012 |
20120309084 | MICROCHIP FOR NUCLEIC ACID AMPLIFICATION REACTION AND A METHOD OF MANUFACTURING THE SAME - To provide a microchip for a nucleic acid amplification reaction which allows high-precision analysis by a simple method. | 12-06-2012 |
20140134077 | SAMPLE LIQUID INJECTION TOOL AND SAMPLE LIQUID HEAT TREATMENT APPARATUS - There is provided a sample liquid injection tool including a reservoir section configured to store a sample liquid, a channel having one end protruding from an outer surface and configured to discharge the sample liquid therein from a protrusion end to an outside, and a heating unit and a filter installed between the reservoir section and the channel to enable passage of the liquid. | 05-15-2014 |
20140241955 | SAMPLE LIQUID INJECTION JIG SET - A liquid injecting jig is provided. The liquid injecting jig includes a jig configuration including a plurality of parts adapted to be in cooperative engagement so as to position a channel within the jig configuration, wherein the jig configuration is adapted to fit an opening through which the channel is adapted to be received so as to expose the channel from the jig configuration. A jig set, a microchip case, and a microchip set are also provided. | 08-28-2014 |
20140311910 | MICROCHIP AND METHOD OF MANUFACTURING MICROCHIP - Provided is a microchip including: an inlet part to which a liquid is injected; a plurality of analysis areas to which the liquid is supplied from the inlet part; and a flow channel which is formed to supply the liquid to the plurality of analysis areas at the same time. | 10-23-2014 |
20150017318 | METHOD FOR FABRICATING MICROCHIP FOR NUCLEIC ACID AMPLIFICATION REACTION - Provided is a method for fabricating a microchip for nucleic acid amplification reaction that is capable of simple and highly accurate analysis. Provided is a method for fabricating a microchip for nucleic acid amplification reaction, the method including a solidification step of drying a reagent solution including at least a part of substances required for a nucleic acid amplification reaction, and a containment step of arranging the reagent solution including the solidified substance in wells that serve as a reaction site for a nucleic acid amplification reaction. In the microchip for nucleic acid amplification reaction fabricated by the fabrication method, since substances required for the nucleic acid amplification reaction are contained by being solidified, non-specific amplification is suppressed in a nucleic acid amplification reaction, which enables highly accurate analysis. | 01-15-2015 |